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1

I. Sathish, Mr, and Mr Raja. V. "Green synthesis and optimization of Carissa carandas Linn. Silver nanoparticles for diabetic treatment." International Journal of Current Research in Medical Sciences 11, no. 6 (2025): 27–39. https://doi.org/10.22192/ijcrms.2025.11.06.003.

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Background: Green synthesis of silver nanoparticles (AgNPs) using medicinal plants has emerged as a promising, eco-friendly approach for therapeutic nanoparticle development. Carissa carandas L., traditionally known for its antidiabetic properties, was selected for the biosynthesis of AgNPs and subsequent in-vitro evaluation Methods: Aqueous root extract of Carissa carandas was used to synthesize AgNPs via microwave-assisted reduction of silver nitrate. The synthesis was optimized using Taguchi design (L9 orthogonal array). Nanoparticles were characterized using UV-Vis spectroscopy, FTIR, SEM,
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2

Durairajan, Sudha, Malarkodi Raja, Gokulakrishnan Adikesavan, and Liyakath ali Abdul Rahman. "Impact of Carissa carandas Linn. Fruit Extract on Streptozotocin-Induced Diabetes Mellitus." Biosciences Biotechnology Research Asia 22, no. 1 (2025): 299–312. https://doi.org/10.13005/bbra/3362.

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ABSTRACT: Carissa carandas is traditionally used as an herbal remedy in Asian countries for diabetes due to its multiple pharmacological activities. The potential activity of the ethanolic extract of C. carandas fruits as an anti-diabetic agent was investigated in this study. Rats with streptozotocin-induced (STZ) diabetes were used to evaluate the effects of the ethanolic extract of C. carandas fruit. Various parameters, including body weight, oral glucose tolerance test, blood glucose levels, biochemical and hematological parameters, antioxidant enzyme activities, DNA damage inhibition, and
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3

Itankar, Prakash R., Sarika J. Lokhande, Prashant R. Verma, Sumit K. Arora, Rajesh A. Sahu, and Arun T. Patil. "Antidiabetic potential of unripe Carissa carandas Linn. fruit extract." Journal of Ethnopharmacology 135, no. 2 (2011): 430–33. http://dx.doi.org/10.1016/j.jep.2011.03.036.

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4

Khatun, Marina, M. Rowshanul Habib, M. Ahasanur Rabbi, et al. "Antioxidant, cytotoxic and antineoplastic effects of Carissa carandas Linn. leaves." Experimental and Toxicologic Pathology 69, no. 7 (2017): 469–76. http://dx.doi.org/10.1016/j.etp.2017.03.008.

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Sharma, Kavita* Bhukele Dipak Patil Krutika Pingle Ashwini. "A Review On: Herbal Uses of Carissa Carandas." International Journal of Pharmaceutical Sciences 3, no. 1 (2025): 2345–56. https://doi.org/10.5281/zenodo.14754474.

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Carissa carandas Linn. (family: Apocynaceae) is a well-known tropical plant in India that is known as Karvand/Karanda. [1] This native berry fruit is prized for both its superior nutritional worth and its distinct sour flavor. The dearth of knowledge shows how underappreciated and ignored the fruit is in spite of its enormous nutritional potential. [2] The purpose of the study was to investigate the potential uses of fresh, dried fruit and leaf in Ayurvedic medicine for treating a wide range of illnesses. [18] Traditionally, the entire plant, including the fruit, root, and leaf, was used to tr
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6

Desai, Rutuja, Sameer Nadaf, Ashwini Gawade, and Ashwin Kuchekar. "Investigation of Anti-Angiogenic and Cytotoxic Properties of Carissa Carandas Linn. Extracts Using In Vivo and In Vitro Assays." Journal of Cancer Research and Reviews 1, no. 1 (2024): 30. http://dx.doi.org/10.5455/jcrr.20240512042153.

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Aim: The study aims to evaluate the anti-angiogenic and cytotoxic properties of Carissa carandas Linn., a medicinal plant traditionally used in India for various ailments. Method: The plant's leaf extracts were prepared using methanol and n-hexane solvents and subjected to phytochemical analysis, revealing the presence of compounds like tannins, triterpenoids, and flavonoids. The antioxidant potential of the extracts was assessed, with the fruit extract showing remarkable scavenging activity against free radicals. The anti-angiogenic activity was examined using the Chorioallantoic Membrane (CA
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7

Parvin, Most Nazma. "Phytochemical screening, antinociceptive, anthelmintic and cytotoxicity studies of the leaves of Carissa carandas Linn. (Family: Apocynaceae)." International Journal of Scientific Reports 4, no. 5 (2018): 119. http://dx.doi.org/10.18203/issn.2454-2156.intjscirep20181849.

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<em><em></em></em><p class="abstract"><strong>Background:</strong> <em>Carissa carandas </em>Linn. (Bengali name- Karamya, Karancha, Karamcha, English name-Karaunda) commonly known as Karanda is a widly used medicinal plants belongs to apocynaceae family<em>. </em>The various plant parts of <em>C. carandas </em>have been used for ethnomedicine in the treatment of human diseases, such as diarrhea, stomachic, anorexia, intermittent fever, mouth ulcer and sore throat, syphilitic pain, burning sensation, scabies and epil
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8

Khuanekkaphan, Monsicha, Warachate Khobjai, Chanai Noysang, Nakuntwalai Wisidsri, and Suradwadee Thungmungmee. "Bioactivities of karanda (Carissa carandas Linn.) fruit extracts for novel cosmeceutical applications." Journal of Advanced Pharmaceutical Technology & Research 12, no. 2 (2021): 162. http://dx.doi.org/10.4103/japtr.japtr_254_20.

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Neimkhum, Waranya, Songyot Anuchapreeda, Wei-Chao Lin, Shang-Chian Lue, Kuan-Han Lee, and Wantida Chaiyana. "Effects of Carissa carandas Linn. Fruit, Pulp, Leaf, and Seed on Oxidation, Inflammation, Tyrosinase, Matrix Metalloproteinase, Elastase, and Hyaluronidase Inhibition." Antioxidants 10, no. 9 (2021): 1345. http://dx.doi.org/10.3390/antiox10091345.

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In this study, the potential of Carissa carandas Linn. as a natural anti-aging, antioxidant, and skin whitening agent was studied. Various parts of C. carandas, including fruit, leaf, seed, and pulp were sequentially extracted by maceration using n-hexane, ethyl acetate, and ethanol, respectively. High-performance liquid chromatography, Folin–Ciocalteu, and Dowd method were used to investigate their chemical compositions. The inhibitory activities of oxidation process, matrix metalloproteinases (MMPs), elastase, hyaluronidase, and tyrosinase were analyzed. Cytotoxicity was determined by 3-(4,5
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10

Madathala Sreekanth, Veerasamy Hari Baskar, and Nunna Bheema Lingeswara Prasad. "Assessment of potential antiurolithiatic property of Carissa carandas Linn. leaves on zinc disc insertion - incited urolithiasis in wistar male albino rats." International Journal of Research in Pharmaceutical Sciences 11, no. 2 (2020): 2684–94. http://dx.doi.org/10.26452/ijrps.v11i2.2285.

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The goal of the research was to assess the antiurolithiatic property of Carissa carandas Linn. leaf extract in rats. The rats were segregated into 6 groups of 6 rats each. Calcium oxalate urolithiasis was surgically incited by insertions of pre-weighed and sterile zinc disc in bladders of animals. This was also followed by supplementing 0.75% v/v ethane-1, 2-diol (Ethylene glycol) in quaffing water ad libitum for 28 days. Upon postsurgical recovery period (3 days), Cystone (750 mg/kg) and three doses of EELCC (Ethanolic extract of leaves of Carissa carandas Linn.) namely 100, 200, and 400 mg/k
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11

Pattarith, Kongsak. "Dye-Sensitized Solar Cells Using Carissa carandas Linn. Fruits Extract as Dye Sensitizer." Asian Journal of Chemistry 27, no. 11 (2015): 4190–92. http://dx.doi.org/10.14233/ajchem.2015.19485.

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12

Ekalu, Abiche, Rachael Gbekele-Oluwa Ayo, James Dama Habila, and Ibrahim Hamisu. "A mini-review on the phytochemistry and biological activities of selected Apocynaceae plants." Journal of Herbmed Pharmacology 8, no. 4 (2019): 269–73. http://dx.doi.org/10.15171/jhp.2019.39.

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This review aims at studying the phytochemistry and biological activities of some selected Apocynaceae plants. Eleven members of this family were reviewed for their phytochemistry and biological activities. Interestingly, the commonly isolated compounds reported from Mondia whitei (Hook.f.) Skeels, Secondatia floribunda A. DC, Carissa carandas, Tabernaemontana divaricate, Nerium oleander, Wrightia tinctoria, Tabernaemontana divaricate, Alstonia scholaris, Carrisa spinarum Linn, Thevetia peruviana and Caralluma lasiantha were triterpenoids, flavonoids, phytosterols, cardiac glycosides and ligna
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,, Elidarni, Husnarika Febriani, and Rahmadina ,. "Pengaruh Ekstrak Daun Samarinda (Carissa carandas Linn.) Terhadap Histopatologi Aorta Tikus (Rattus norvegicus) Hiperkolesterolemia." BEST Journal (Biology Education, Sains and Technology) 4, no. 2 (2021): 332–38. http://dx.doi.org/10.30743/best.v4i2.4548.

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Hiperkolesterolemia merupakan suatu kondisi tubuh yang mengalami penurunan estrogen yang menyebabkan kadar Low Density Lipoprotein (LDL) meningkat. Daun Samarinda adalah jenis tanaman dari Famili Apocynaceae yang umumnya digunakan sebagai tanaman obat karena mengandung senyawa berkhasiat obat yaitu flavonoid. Senyawa flavonoid dapat memperbaiki kerusakan sel endotel dinding aorta jantung tikus hiperkolesterolemia. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak daun samarinda (Carissa carandas Linn.) dalam memperbaiki ketebalan dinding aorta jantung tikus putih (Rattus nor
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14

Lekhika, Bansal. "CARISSA CARANDAS AS A NATURAL COLOURANT AND ITS EFFECT ON PHYSICAL AND FASTNESS PROPERTIES OF SILK." Biolife 2, no. 2 (2022): 470–74. https://doi.org/10.5281/zenodo.7204937.

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<strong>ABSTRACT</strong> &nbsp; The present work was focussed to determine the effect of degumming on physical and fastness properties of silk. Study was also aimed to determine the effect of&nbsp; <em>Termenalia</em> <em>bellerica</em> Roxb. and <em>Punica</em> <em>granatum</em> Linn. as a natural mordant and Stannous chloride<em> ,</em>Potash alum as metal mordants<em>. Carissa carandas </em>Linn. has imparted range of brown colour on silk. <em>Termenalia bellerica </em>Roxb.<em> and Punica granatum </em>Linn. as natural mordants showed increase in physical properties with good to very good
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15

K Amaranath, Swathi, Dr Nagarathna Amresh, and Dr Kiruthika Balasubramanian. "Radical Scavenging, Preliminary Phytochemical Screening and DNA Protective Effect of Carissa Carandas Linn Plant Leaves." International Journal of pharma and Bio Sciences 12, no. 1 (2021): 1–8. http://dx.doi.org/10.22376/ijpbs.2021.12.1.b1-8.

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16

Devi, Nirmala, Ajay Kumar Gupta, and Sunil Kumar Prajapati. "Comparative Antiproliferative activity of aerial parts of few Apocynaceae plants in HepG2, HT29 and SK-OV3 Human cancer cell lines." Journal of Drug Delivery and Therapeutics 9, no. 4-s (2019): 1195–202. http://dx.doi.org/10.22270/jddt.v9i4-s.3906.

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Aims: Apocynaceae family is the 5th largest medicinal plant family rich in potent secondary metabolites such as Alkaloids, Cardiac glycosides,Terpenoids, irridoid/secoirridoids, flavonoids and Phenolic contents. The present study was aimed to evaluate and compare in-vitroantiproliferative activity of three plants of this family.Methods: Aerial parts of Carissa carandas Linn. (C), Nerium indicum Mill. (N) and Wrightia tinctoria RBr. (W), were collected and dried. Thepowdered drugs were extracted in Ethanol (1), 60% Ethanol (2) and Water (3). Estimation of Phytoconstituents performed using stand
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Lailerd, Manaschanok, Thiri Wai Linn, Narissara Lailerd, Duangporn Amornlerdpison, and Arisa Imsumran. "Assessment of Antidiabetic and Anti-Inflammatory Activities of Carissa carandas Linn Extract: In Vitro and In Vivo Study." Applied Sciences 13, no. 11 (2023): 6454. http://dx.doi.org/10.3390/app13116454.

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This study investigated the effects of aqueous fruit extracts of Carissa carandas (CCA) on inflammation and insulin resistance using an in vitro cellular model, in vivo high-fat diets, and a streptozotocin-induced type 2 diabetic (T2DM) rat model. CCA significantly ameliorated inflammation by decreasing nitric oxide production in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages. Interestingly, CCA showed anti-insulin resistance activities, as it significantly improved glucose uptake and decreased glycerol release in LPS-induced 3T3-L1 adipocytes. In vivo studies showed that a high dose o
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18

Dhodi, Jayesh B., Deepavali R. Thanekar, Snehal N. Mestry, and Archana R. Juvekar. "Carissa carandas Linn. fruit extract ameliorates gentamicin–induced nephrotoxicity in rats via attenuation of oxidative stress." Journal of Acute Disease 4, no. 2 (2015): 135–40. http://dx.doi.org/10.1016/s2221-6189(15)30023-8.

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Kaban, Vera Estefania, Nasri Nasri, Hariyadi Dharmawan Syahputra, Muhammad Fauzan Lubis, and Denny Satria. "Uji Aktivitas Antibakteri Ekstrak Daun Karenda (Carissa carandas Linn.) Terhadap Bakteri Propionibacterium acne dan Staphylococcus epidermidis." Journal of Pharmaceutical and Health Research 4, no. 1 (2023): 91–96. http://dx.doi.org/10.47065/jharma.v4i1.3181.

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Karenda leaves contain flavonoids, steroids or triterpenoids, saponins, and tannins that act as antimicrobial compounds. The aim of the study was to determine the antibacterial activity of the ethanol extract of Karenda leaves against several acne-causing bacteria. The research method involved characterizing the simplicia of karenda leaves and extract preparation by maceration using 96% ethanol as a solvent. and test the antibacterial activity of the ethanol extract of Karenda leaves using the agar diffusion method. The bacteria used were Propionibacterium acnes and Staphylococcus epidermis. T
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Anjali, Deshmukh, and Bansa Lekhika. "SAPINDUS EMARGINATUS VAHL AS A NATURAL SCOURUNG AGENT IN DYEING OF COTTON WITH CARISSA CARANDAS LEAF EXTRACT." Biolife 2, no. 2 (2022): 599–604. https://doi.org/10.5281/zenodo.7214322.

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&nbsp; <strong>ABSTRACT</strong> &nbsp; Comparative study of <em>Sapindus</em> <em>emarginatus</em> vahl as natural soap and synthetic soap for scouring of cotton was carried out. Scoured samples were tested for physical properties expressed as cotton scoured with <em>Sapindus emarginatus</em> vahl. showed high tearing strength.&nbsp; Scoured cotton samples were mordanted with <em>Terminalia</em> <em>chebula</em> Linn, <em>Punica</em> <em>granatum</em> Linn as natural mordants and stannous chloride, potash alum as metal mordants.&nbsp; Physical and fastnesss properties of mordanted and dyed co
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Madari, Steffi S., Pratik P. Dhavan, and Nisha J. Shah. "BIOGENIC SYNTHESIS, CHARACTERIZATION OF SILVER NANOPARTICLES FROM CARISSA CARANDAS LEAF EXTRACT AND ITS PHARMACOLOGICAL ACTIVITIES." International Research Journal of Pharmacy 11, no. 12 (2020): 46–52. http://dx.doi.org/10.7897/2230-8407.1112107.

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A Plant-mediated synthesis of nanoparticles is considered as a representative approach to environment benignity in material synthesis to avoid chemical toxicity. In this present study, we report an eco-friendly technique for the preparation of silver nanoparticles (AgNPs) from aqueous leaves extract of Carissa carandas Linn, and the evaluation of their pharmacological activities. The formation of AgNPs is confirmed by UV-Visible spectrum which peak highest at 436nm that corresponds to surface plasmon resonance of AgNPs. The shape and size of synthesized AgNPs were determined by HR-TEM and FEG-
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Faizan, Mohd, Tanzeela Khan, Yusra Qureshi, and Naseem Akhtar Khan. "Clinical Study on the Management of Uterine Fibroid (Sal‘āt- al-Raḥim) with an Unani Polyherbal Formulation: A Case Report." International Journal of AYUSH Case Reports 9, no. 2 (2025): 358–67. https://doi.org/10.70805/ija-care.v9i2.706.

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In the Unani system of medicine, uterine fibroids are referred to as Sal'āt-al-Raḥim. Also known as leiomyomas, these benign tumors are composed of smooth muscle and connective tissue within the myometrium. Uterine fibroids are a major health concern, with their prevalence varying across ethnic groups. Studies suggest that over 50% of women above the age of 45 are affected. This paper presents a case report demonstrating significant symptomatic improvement and normalization of myometrial thickness following Unani treatment. A female patient who presented with lower abdominal pain, lower back
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Zubair, Momina, Muhammad Imran Tousif, Naheed Riaz, et al. "In vitro antioxidant and in silico enzyme inhibition studies of Carissa carandas Linn.: potential ingredient for nutraceutical development." International Journal of Food Properties 27, no. 1 (2024): 1–26. http://dx.doi.org/10.1080/10942912.2024.2409122.

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Monika S, Thirumal M, Kumar P R. "Identification Of Bioactive Phytochemicals By GC-MS Profiling, Phytochemical Screening, And TLC Using Methanolic Extract Of Carissa Carandas Linn Leaf." Journal of Pharmaceutical Negative Results, December 5, 2022, 4439–44. http://dx.doi.org/10.47750/pnr.2022.13.s08.568.

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Background Carissa carandas (Apocynaceae) is a thorny evergreen shrub known as Karonda. It has small berry-shaped fruits, used as an additive in many pickles or spices in northern India. Objective The objective was to identify the phytochemical constituents, gas chromatography-mass spectrometry (GC-MS), and TLC screening by using a methanolic extract from the leaves of Carissa carandas. Methods and materials Leaves of C. carandas were collected, shade dried, pulverized, and extracted successively with methanol by the Soxhlet technique. The crude extracts were later exposed to phytochemical scr
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"PHARMACOGNOSTICAL STUDIES OF Carissa carandas Linn Leaves." International Journal of Biology, Pharmacy and Allied Sciences 13, no. 1 (2024). http://dx.doi.org/10.31032/ijbpas/2024/13.1.7563.

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Swathi, K. Amaranath Dr Nagarathna Amresh and Kiruthika Balasubramanian*. "ANTIOXIDANT ANALYSIS OF CARISSA CARANDAS LINN PLANT LEAVES." May 3, 2020. https://doi.org/10.5281/zenodo.3783521.

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<em>Many chemical species are involved in the control of oxidative chemical processes in all biological systems, and these are often referred to as an antioxidant.</em><em> Oxygen is an essential component for all living organism. A part of oxygen taken into living cells is converted into a severe harmful reactive oxygen species(ROS) and free radicals. The excessive production of free radicals or deficiencies in antioxidant defenses leads to the appearance of &quot;oxidative stress&rdquo;</em><em>.</em><em> These harmful effects are balanced by the action of enzymic and non-enzymic antioxidant
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Singh, Sonia, Meenakshi Bajpai, and Pradeep Mishra. "Pharmacognostical evaluation of indigenous herbal drug: Carissa carandas Linn. fruit." Annals of Phytomedicine: An International Journal 9, no. 2 (2020). http://dx.doi.org/10.21276/ap.2020.9.2.25.

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Kapoor, S. L., P. C. Sharma, V. Chandra, and L. D. Kapoor. "Epidermal and Venation Studies in Apocynaceae-II." Nelumbo, May 20, 2024, 372–76. http://dx.doi.org/10.20324/nelumbo/v11/1969/76004.

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Epidermal characters and venation pattern of the leaves of nine species of Apocynaceae, viz. Acokanthera oppositifolia (Lam.) Codd (A. venenata G. Don), Allamanda cathartica Linn. (2 cultivars), Alstonia scholaris R. Br., Carissa carandas Linn., Cerbera manghas Linn., Ervatamia coronaria Stapf (2 cultivars-single and double flower forms), Mascarenhasia variegata Britt. &amp; Renole (M. elastica K. Schum.), Thevetia peruviana (Pers.) Schum. and Wrightia coccinea Sims., have been described.
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Kapoor, S. L., and R. Mitra. "Epidermal and Venation Studies in Apocynaceae-VI." Nelumbo, May 21, 2024, 68–80. http://dx.doi.org/10.20324/nelumbo/v21/1979/75394.

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The papa describes and evaluates the taxonomic value of the epidermal features and venation pattern of the leaves of 11 species of Apocynaceae viz., Carissa carandas Linn., C. congesta Wight, C. hirsuta Roth, C. inemis Vahl, C. opaca Stapf ex Parker, C. paucinervia A. DC., C. spinarum Linn., C. suavissima Bedd. ex Hook.f., Trachelospermum lucidum (D. Don) K. Schum., Vinca major Linn. and Willoughbeia edulis Roxb.
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Rajesham, V. V., Hima Sowmya Kandoti, Mitta Raghavendra, P. Roshan Ali, and T. Rama Rao. "Nephroprotective Activity of Ethanolic Extract of Carissa carandas Leaves against Gentamicin-Induced Acute Kidney Injury in Wistar Albino Rats." Journal of Pharmaceutical Research International, December 15, 2021, 279–86. http://dx.doi.org/10.9734/jpri/2021/v33i58a34117.

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The present study was aimed to evaluate the nephroprotective activity of ethanolic extract of Carissa carandas Linn. Leaves (EECC) in Gentamicin-induced nephrotoxicity in Wistar albino rats. The renal damage was induced by Gentamicin (80mg/kg body weight, i.p.). Nephroprotective activity was investigated by the administration of EECC at two different doses (100 and 200mg/kg body weight, p.o) for 28 days and by assessing serum parameters, renal oxidative stress markers and histopathological studies. Gentamicin-treated animals showed an increase in serum creatinine, uric acid, urea, and malondia
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Hegde, K., SP Thakker, AB Joshi, CS Shastry, and KS Chandrashekhar. "Anticonvulsant Activity of Carissa carandas Linn. Root Extract in Experimental Mice." Tropical Journal of Pharmaceutical Research 8, no. 2 (2009). http://dx.doi.org/10.4314/tjpr.v8i2.44519.

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SUDHA, D., R. MALARKODI, A. GOKULAKRISHNAN, and A. R. LIYAKATH ALI. "LC-MS/MS AND GC-MS PROFILING AND THE ANTIOXIDANT ACTIVITY OF CARISSA CARANDAS LINN. FRUIT EXTRACTS." International Journal of Pharmacy and Pharmaceutical Sciences, June 1, 2024, 39–45. http://dx.doi.org/10.22159/ijpps.2024v16i6.50818.

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Objective: The present study was carried out with three varieties (green, pink, and sweet) of Carissa carandas fruit extract for the identification of phytochemical constituents in C. carandas fruit extracts using Liquid Chromatography-Mass Spectrometry (LC-MS/MS) and Gas Chromatography-Mass Spectrometry (GCMS) Methods: LC MS/MS and GCMS analysis were adopted to study three varieties of C. carandas fruit, namely green, pink, and sweet, using different solvent extractions such as ethanol, methanol, and aqueous. Results: High levels of phenolic acids and flavonoids in the green variety were bene
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Tesfaye, Tamrat, and Yesudass Dominic Ravichadran. "Traditional Uses, Pharmacological Action and Phytochemical Analysis of Carissa carandas Linn.: A Review." Natural Products Chemistry & Research 06, no. 05 (2018). http://dx.doi.org/10.4172/2329-6836.1000334.

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Anunthawan, Thitiporn, and Thipwarin Rimlumduan. "Antioxidant activity, anti-tyrosinase activity, and lipstick pigments of Oryza sativa Linn. and Carissa carandas Linn. extracts." Journal of Applied Pharmaceutical Science, 2023. http://dx.doi.org/10.7324/japs.2023.145623.

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35

Singh, Sonia, and Nitin Agarwal. "Study the Pharmacognostic profile, Antiradical and Hepatoprotective potential of Carissacarandas Linn. fruit extract." Recent Patents on Food, Nutrition & Agriculture 12 (March 2, 2022). http://dx.doi.org/10.2174/2212798412666220302163553.

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Aims: Carissa carandas Linn. is a thorny shrub (Family: Apocynaceae), commonly called as Karonda. The shrub can be grown in tropical and subtropical climate region. Methods and Material: The objective of the experimental work was to analyse the efficacy of fruit extract of C. carandas Linn. with respect to hepatoprotective property using supportive evidence of in vitro and in vivo antiradical activity. The antioxidant activity of ethanolic fruit extract was determined by 2, 2-diphenyl-1-picrylhydrazyl (DPPH), hydrogen peroxide and nitric oxide free radical scavenging assay, using Ascorbic acid
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"Antidiabetic activity (In vitro alpha amylase inhibitory) of ethanol extract of Carissa carandas Linn. roots." International Journal of Pharmaceutical Research 12, no. 03 (2020). http://dx.doi.org/10.31838/ijpr/2020.12.03.002.

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Neimkhum, Waranya, Songyot Anuchapreeda, Wei-Chao Lin, Shang-Chian Lue, Kuan-Han Lee, and Wantida Chaiyana. "Enhancement of stability and dermal delivery of Carissa carandas Linn. leaf extract by liquid crystals." Journal of Drug Delivery Science and Technology, February 2023, 104258. http://dx.doi.org/10.1016/j.jddst.2023.104258.

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Pewlong, Wachiraporn, Surasak Sajjabut, Jaruratana Eamsiri, and Sirilak Chookaew. "Evaluation of Antioxidant activities, Anthocyanins, Total Phenolic Content, Vitamin C Content and Cytotoxicity of Carissa carandas Linn." Chiang Mai University Journal of Natural Sciences 13, no. 1 (2014). http://dx.doi.org/10.12982/cmujns.2014.0053.

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Thitilertdecha, N., and P. Pintathong. "The Antioxidant and Anti-Tyrosinase Activities of Carissa carandas Linn. Fruit Extracts and their Applications in Cosmetics." Indian Journal of Pharmaceutical Sciences 84, no. 5 (2022). http://dx.doi.org/10.36468/pharmaceutical-sciences.1017.

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Mukadam, S. J., and P. M. Haldankar. "Effect of Paclobutrazol and Post Flowering Foliar Sprays of Nutrients for Accelerating Harvesting of Karonda (Carissa carandas Linn.)." Journal of Plant Studies 2, no. 1 (2012). http://dx.doi.org/10.5539/jps.v2n1p145.

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Fartyal, Meenakshi. "Comparative study of antifungal potential of various extracts of leaves of Carissa carandas Linn., Nerium oleander Linn. and Allamanda cathartica Linn. against human fungal pathogen Candida albicans." Vegetos, October 27, 2023. http://dx.doi.org/10.1007/s42535-023-00756-5.

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Bons, Harsimrat K., Gurpreet Kaur Dhillon, Jagdish Grover, and Richa Arora. "Bioprospecting Augmented Production of Neutraceutically Rich Karonda (<i>Carissa carandus</i> Linn) by Osmotic Dehydration using Response Surface Methodology." Indian Journal of Nutrition and Dietetics, December 10, 2021, 481–88. http://dx.doi.org/10.21048/ijnd.2021.58.4.27996.

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Abstract:
Karonda (Carissa carandus Linn) is hardy, indigenous shrub with spines, generally used as bio fence around orchards. It bears small berry like edible fruits with higher nutraceutical value. Mature fruits of karonda are sour and astringent with immense bioactive compounds. Optimization was carried out with Central Composite Design (CCD) for standardizing processing conditions of osmotically dehydrated karonda fruit with respect to three variables viz. sugar concentration (50-70 °Brix), immersion time (1-4 hours) and temperature (35-45 °C) for three responses viz. rehydration ratio, water loss a
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