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Journal articles on the topic 'Carlsbad Cave'

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Published: 7 June 2025

Last updated: 16 July 2025

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1

Duncan, Tammi, Margaret Werner-Washburne, and Diana Northup. "Diversity of siderophore-producing bacterial cultures from Carlsbad Caverns National Park caves, Carlsbad, New Mexico." Journal of Cave and Karst Studies 83, no. 1 (2021): 29–43. http://dx.doi.org/10.4311/2019es0118.

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Siderophores are microbially-produced ferric iron chelators. They are essential for microbial survival, but their presence and function for cave microorganisms have not been extensively studied. Siderophores are classified based on the common functional groups (catechols, hydroxamates, carboxylates, and mixed) that coordinate to ferric (Fe3+) iron. Cave environments are nutrient-limited and previous evidence suggests siderophore usage in carbonate caves. We hypothesize that siderophores are likely used as a mechanism in caves to obtain critical ferric iron. Cave bacteria were collected from lo

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2

Burger, Paul A. "Cave and karst management at Carlsbad Caverns National Park." Zeitschrift für Geomorphologie, Supplementary Issues 62, no. 3 (2021): 85–124. http://dx.doi.org/10.1127/zfg_suppl/2021/0692.

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3

Ingraham, Neil L., Jenny B. Chapman, and John W. Hess. "Stable isotopes in cave pool systems: Carlsbad Cavern, New Mexico, U.S.A." Chemical Geology: Isotope Geoscience section 86, no. 1 (1990): 65–74. http://dx.doi.org/10.1016/0168-9622(90)90006-x.

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4

Read, Kaitlin, Leslie Melim, Ara Winter, and Diana Northup. "Bacterial diversity in vadose cave pools: evidence for isolated ecosystems." Journal of Cave and Karst Studies 83, no. 4 (2021): 163–88. http://dx.doi.org/10.4311/2020mb0120.

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Microbial diversity of cave pools, especially vadose pools, has received relatively little attention. To help fill this gap, this study reports on the bacterial diversity of 17 pools in three New Mexican arid land caves: Carlsbad Cavern, Lechuguilla Cave, and Hell Below Cave. These pools are spread throughout the caves and, with two exceptions, are not connected. The pools share a basic water chemistry, with fresh water of the calcium-magnesium-bicarbonate type. These 17 pools have Chao1 values between 40 and 1738; the Shannon diversity averages 4.6 ± 1.1, ranging from 2.6 to 6.4; and the Simp

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Melim, Leslie A., and Michael N. Spilde. "A New Unified Model For Cave Pearls: Insights from Cave Pearls in Carlsbad Cavern, New Mexico, U.s.a." Journal of Sedimentary Research 88, no. 3 (2018): 344–64. http://dx.doi.org/10.2110/jsr.2018.21.

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6

Polyak, Victor J. "Alunite, Natroalunite and Hydrated Halloysite in Carlsbad Cavern and Lechuguilla Cave, New Mexico." Clays and Clay Minerals 44, no. 6 (1996): 843–50. http://dx.doi.org/10.1346/ccmn.1996.0440616.

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7

Cunningham, K. I., D. E. Northup, R. M. Pollastro, W. G. Wright, and E. J. LaRock. "Bacteria, fungi and biokarst in Lechuguilla Cave, Carlsbad Caverns National Park, New Mexico." Environmental Geology 25, no. 1 (1995): 2–8. http://dx.doi.org/10.1007/bf01061824.

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8

Calaforra, Jose-Maria, and Waele Jo De. "New peculiar cave ceiling forms from Carlsbad Caverns (New Mexico, USA): The zenithal ceiling tube-holes." Geomorphology 134, no. 1-2 (2011): 43–48. https://doi.org/10.5281/zenodo.13438801.

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(Uploaded by Plazi for the Bat Literature Project) During a trip to the Hall of the White Giant, Carlsbad Caverns (NM, USA) cigar-shaped vertically upward developing holes were observed on the ceiling at different heights of the passages. They have a circular crosssection with diameters of 1 to some centimetres and taper out towards their upper end. Their walls are smooth and their bottom edges are sharp, while their length can reach several decimetres. Sometimes gypsum can be found inside. They often occur randomly distributed in groups and their development is not necessarily controlled by f

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Calaforra, Jose-Maria, and Waele Jo De. "New peculiar cave ceiling forms from Carlsbad Caverns (New Mexico, USA): The zenithal ceiling tube-holes." Geomorphology 134, no. 1-2 (2011): 43–48. https://doi.org/10.5281/zenodo.13438801.

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(Uploaded by Plazi for the Bat Literature Project) During a trip to the Hall of the White Giant, Carlsbad Caverns (NM, USA) cigar-shaped vertically upward developing holes were observed on the ceiling at different heights of the passages. They have a circular crosssection with diameters of 1 to some centimetres and taper out towards their upper end. Their walls are smooth and their bottom edges are sharp, while their length can reach several decimetres. Sometimes gypsum can be found inside. They often occur randomly distributed in groups and their development is not necessarily controlled by f

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10

Calaforra, Jose-Maria, and Waele Jo De. "New peculiar cave ceiling forms from Carlsbad Caverns (New Mexico, USA): The zenithal ceiling tube-holes." Geomorphology 134, no. 1-2 (2011): 43–48. https://doi.org/10.5281/zenodo.13438801.

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(Uploaded by Plazi for the Bat Literature Project) During a trip to the Hall of the White Giant, Carlsbad Caverns (NM, USA) cigar-shaped vertically upward developing holes were observed on the ceiling at different heights of the passages. They have a circular crosssection with diameters of 1 to some centimetres and taper out towards their upper end. Their walls are smooth and their bottom edges are sharp, while their length can reach several decimetres. Sometimes gypsum can be found inside. They often occur randomly distributed in groups and their development is not necessarily controlled by f

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11

Calaforra, Jose-Maria, and Waele Jo De. "New peculiar cave ceiling forms from Carlsbad Caverns (New Mexico, USA): The zenithal ceiling tube-holes." Geomorphology 134, no. 1-2 (2011): 43–48. https://doi.org/10.5281/zenodo.13438801.

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(Uploaded by Plazi for the Bat Literature Project) During a trip to the Hall of the White Giant, Carlsbad Caverns (NM, USA) cigar-shaped vertically upward developing holes were observed on the ceiling at different heights of the passages. They have a circular crosssection with diameters of 1 to some centimetres and taper out towards their upper end. Their walls are smooth and their bottom edges are sharp, while their length can reach several decimetres. Sometimes gypsum can be found inside. They often occur randomly distributed in groups and their development is not necessarily controlled by f

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12

Cunningham, K. I., and E. J. LaRock. "Recognition of Microclimate Zones Through Radon Mapping, Lechuguilla Cave, Carlsbad Caverns National Park, New Mexico." Health Physics 61, no. 4 (1991): 493–500. http://dx.doi.org/10.1097/00004032-199110000-00004.

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13

Turin, H. J., Mitchell A. Plummer, and Fred M. Phillips. "Tritium, Chlorine-36, and water isotopologue profiles from Lechuguilla Cave and Carlsbad Cavern, New Mexico, USA." Applied Geochemistry 138 (March 2022): 105212. http://dx.doi.org/10.1016/j.apgeochem.2022.105212.

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14

Calaforra, Jose-Maria, and Jo De Waele. "New peculiar cave ceiling forms from Carlsbad Caverns (New Mexico, USA): The zenithal ceiling tube-holes." Geomorphology 134, no. 1-2 (2011): 43–48. http://dx.doi.org/10.1016/j.geomorph.2011.02.032.

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15

Geluso, Keith. "Winter Activity of Brazilian Free-Tailed Bats (Tadarida brasiliensis) at Carlsbad Cavern, New Mexico." Southwestern Naturalist 53, no. 2 (2008): 243–47. https://doi.org/10.5281/zenodo.14815151.

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(Uploaded by Plazi for the Bat Literature Project) The Brazilian free-tailed bat (Tadarida brasiliensis) generally is considered a migratory species in western North America. Throughout the southwestern United States, however, winter records are known from many scattered locations. Here I report on T. brasiliensis exiting and entering a cave in southern New Mexico from November to March. I observed that a winter colony of Brazilian free-tailed bats at Carlsbad Cavern was comprised of males and females of different ages, and in February and March, I documented that numbers of individuals inhabi

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Shapiro, Hannah G., Adam S. Willcox, Emma V. Willcox, and Michelle L. Verant. "U.S. National Park visitor perceptions and behavioral intentions towards actions to prevent white-nose syndrome." PLOS ONE 17, no. 11 (2022): e0278024. http://dx.doi.org/10.1371/journal.pone.0278024.

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In the United States, the discovery and spread of white-nose syndrome (WNS) has drastically changed how bats and caves are managed. The U.S. National Park Service has been instrumental in the national response to WNS, as it manages extensive cave resources and has a close relationship with the public. However, managers lack information on visitor support for disease prevention measures designed to slow the spread of WNS and minimize human disturbance of vulnerable bat populations. This study utilized the Theory of Planned Behavior to determine how visitor attitudes, subjective norms, and perce

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17

Hristov, Nickolay I., Margrit Betke, Diane E. H. Theriault, Angshuman Bagchi, and Thomas H. Kunz. "Seasonal variation in colony size of Brazilian free-tailed bats at Carlsbad Cavern based on thermal imaging." Journal of Mammalogy 91, no. 1 (2010): 183–92. https://doi.org/10.5281/zenodo.14815741.

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(Uploaded by Plazi for the Bat Literature Project) The colony of Brazilian free-tailed bats (Tadarida brasiliensis) at Carlsbad Cavern, New Mexico, is a wellknown example of this highly gregarious and conspicuous species in North America. For nearly a century researchers have tried to estimate the size of this colony, but different census methods and lack of repeatability have resulted in questionable estimates that have given rise to poorly understood but highly popularized, longterm population trends for this migratory species. In this study we present accurate seasonal estimates of colony s

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Lyles, J. T. M., and D. G. Davis. "A brief history of exploration in Lechuguilla Cave in New Mexico, USA." Boletín Geológico y Minero 127, no. 1 (2016): 111–29. http://dx.doi.org/10.21701/bolgeomin.127.1.008.

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Lechuguilla Cave, a complex three-dimensional cave with a single known entrance, is located in remote desert terrain in Carlsbad Caverns National Park, in southeastern New Mexico, USA. The Guadalupe Mountains there contain uplifted limestone and dolomite rock in the Permian-age Capitan Reef complex. Hundreds of caves have been found in this region, but Lechuguilla Cave greatly exceeds the size of all others known. It was only a small pit mined for bat guano in the early twentieth century. In the 1970s the Cave Research Foundation performed digs at the bottom, where profuse air movement had bee

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19

Rigby, J. Keith, and Baba Senowbari-Daryan. "Gigantospongia, new genus, the largest known Permian sponge, Capitan limestone, Guadalupe Mountains, New Mexico." Journal of Paleontology 70, no. 3 (1996): 347–55. http://dx.doi.org/10.1017/s0022336000038294.

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Several specimens of the large, discoidal, new inozoid genus and species, Gigantospongia discoforma, have been discovered in the Upper Permian, Upper Capitan Limestone in the northern Guadalupe Mountains of New Mexico, near Carlsbad Caverns. The holotype is nearly 2.5 meters across, as exposed, and ranges from 8-20 mm thick, with numerous canals transverse and parallel to the principal plane. These canals are approximately 1 mm in diameter and separated by tracts 1-2 mm thick. Thickened dermal and gastral layers, each approximately 1 mm thick, occur at tops and bases of both the holotype and a

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20

Metzler, Eric, and Edward Knudson. "A new species of Elasmia Möschler from New Mexico and Texas, and a new subspecies of Elasmia mandela (Druce) from Texas and Oklahoma (Lepidoptera, Notodontidae, Nystaleinae)." ZooKeys 149 (November 24, 2011): 51–67. https://doi.org/10.3897/zookeys.149.1519.

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<i>Hippia packardii</i> (Morrison) and <i>Hippia insularis</i> (Grote) are moved to the genus <i>Elasmia</i> Möschler as <b>comb. n.</b> <i>Elasmia cave </i>Metzler<i>, </i><b>sp. n.</b> is described from New Mexico and Texas, and <i>Elasmia mandela santaana </i>Metzler & Knudson<i>, </i><b>ssp. n.</b> is described from Texas and Oklahoma. A key to the species of <i>Elasmia</i> of southwestern U.S. is provided. Adult male and female moths of <i>Elasmia</i> from southwestern U.S. and their genitalia are illustrated.

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21

VOGEL, JAKOB. "Locality and circulation in the Habsburg Empire: disputing the Carlsbad medical salt, 1763–1784." British Journal for the History of Science 43, no. 4 (2010): 589–606. http://dx.doi.org/10.1017/s0007087410001263.

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AbstractBy looking at the fierce debates in the city of Carlsbad in Bohemia around the fabrication of medical salt by a local doctor, David Becher, from 1763 to 1784, the paper examines the interactions between different spheres or levels of circulation of knowledge in the Habsburg Empire. The dispute crystallized around the definition of the product, about its medical qualities and its relation with the water of the local mineral spring. The city's inhabitants contested the vision of the medical experts, fearing that the extraction of the medical salt from the spring water and its sale outsid

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22

Jr., D. R. Clark. "DDT and the Decline of Free-Tailed Bats ( Tadarida brasiliensis ) at Carlsbad Cavern, New Mexico." Archives of Environmental Contamination and Toxicology 40, no. 4 (2001): 537–43. https://doi.org/10.5281/zenodo.14815777.

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(Uploaded by Plazi for the Bat Literature Project) DDT is believed to have caused the population of Brazilian free-tailed bats (Tadarida brasiliensis mexicana) at Carlsbad Cavern to decline severely after 1936. Nevertheless, previous data supporting this hypothesis are limited to a single study from 1974, which indicated that 20% of young free-tails from the cavern may have died of DDE poisoning during their first southward migration. In this study I compared organochlorine residues among samples of free-tails collected in Carlsbad Cavern in 1930, 1956, 1965, 1973, and 1988. Samples of skin cu

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23

Griffin, Dale W., Michael A. Gray, Mark B. Lyles, and Diana E. Northup. "The Transport of Nonindigenous Microorganisms Into Caves by Human Visitation: A Case Study at Carlsbad Caverns National Park." Geomicrobiology Journal 31, no. 3 (2014): 175–85. http://dx.doi.org/10.1080/01490451.2013.815294.

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Polyak, V. J. "Age and Origin of Carlsbad Cavern and Related Caves from 40Ar/39Ar of Alunite." Science 279, no. 5358 (1998): 1919–22. http://dx.doi.org/10.1126/science.279.5358.1919.

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Hieromonk (Denis V. Khmyrov), NIKODIM. "CLAIMS TO ORTHODOX CHURCHES AND CHURCH PROPERTY IN CZECHOSLOVAKIA IN 1920s–1930s. ON HISTORY OF “RESORT” CHURCHES IN CARLSBAD, MARIENBAD AND FRANZENSBAD." Memoirs of NovSU, no. 1 (2025): 138–46. https://doi.org/10.34680/2411-7951.2025.1(56).138-146.

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The paper discusses the so-called resort churches in Czechoslovakia, which before the First World War served Russians who came for treatment to Carlsbad (Karlovy Vary), Marienbad (Mariánské Lázně) and Franzensbad (Františkovy Lázně), and after the war formed parishes of representatives of the Russian Orthodox emigration. The property of the Orthodox Russian Church Abroad after 1918 in all countries of the Russian diaspora was subject to various claims from local government structures or the Soviet government (through representatives of the Renovated Church). New political and religious organiz

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Kolisko, Petr, Milada Sárová, Michele Oliviano, Jakub Krejčí, and Petr Uhlíř. "Influence of carlsbad thermo-mineral water on the autonomic nervous system." Acta Salus Vitae 12, no. 1 (2024): 13–21. http://dx.doi.org/10.58743/asv2024vol12no1.334.

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The drinking cure is an essential part of Karlovy Vary spa treatment. The effect of Karlovy Vary mineral water on the autonomic nervous system has not yet been investigated. Based on case analyses, we hypothesized that the effects of the drinking cure have an effect on the functional activity of the autonomic nervous system. The prospective research study had the character of an experiment in clinical conditions. Research file: Health women n = 15, age 40-50 years. Methodology: Before and 30 min after the experimental sequence, the functional state of the autonomic nervous system was examined

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Polyak, Victor James. "Authigenesis of Trioctahedral Smectite in Magnesium-Rich Carbonate Speleothems in Carlsbad Cavern and Other Caves of the Guadalupe Mountains, New Mexico." Clays and Clay Minerals 48, no. 3 (2000): 317–21. http://dx.doi.org/10.1346/ccmn.2000.0480302.

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28

Henry Onyeka Eleweuwa, Nathan Oghenesuvwe Udele, Taiwo Bakare-Abidola, Chetachukwu Goodness Ezeifegbu, Godstime Destiny Okejevwa, and Jelil Olaoye. "Analysis of energy efficiency in water treatment plants: Present conditions and future directions." World Journal of Advanced Research and Reviews 25, no. 3 (2025): 1717–23. https://doi.org/10.30574/wjarr.2025.25.3.0893.

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Water treatment plants (WTPs) are critical infrastructure for ensuring access to clean and safe water, but they are also significant consumers of energy, contributing to greenhouse gas emissions and operational costs. This study explores the current state of energy efficiency in WTPs, identifying key factors influencing energy consumption, such as treatment technologies, plant design, and operational practices. Through a comprehensive review of literature and case studies, the research highlights the energy-intensive nature of advanced treatment processes like reverse osmosis (RO) and ultravio

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Pérez-Cambrodí, Rafael J., and Pedro Ruiz-Fortes. "Reverse Geometry Hybrid Contact Lens Fitting in a Case of Donor-Host Misalignment after Keratoplasty." International Journal of Keratoconus and Ectatic Corneal Diseases 2, no. 2 (2013): 69–72. http://dx.doi.org/10.5005/jp-journals-10025-1054.

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ABSTRACT Purpose To report the successful outcome obtained after fitting a new hybrid contact lens in a cornea with an area of donor-host misalignment and significant levels of irregular astigmatism after penetrating keratoplasty (PKP). Materials and methods A 41-year-old female with bilateral asymmetric keratoconus underwent PKP in her left eye due to the advanced status of the disease. One year after surgery, the patient referred a poor visual acuity and quality in this eye. The fitting of different types of rigid gas permeable contact lenses was performed, but with an unsuccessful outcome d

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Desmet, S., J. Maertens, K. Bueselinck, and K. Lagrou. "Broad-Range PCR Coupled with Electrospray Ionization Time of Flight Mass Spectrometry for Detection of Bacteremia and Fungemia in Patients with Neutropenic Fever." Journal of Clinical Microbiology 54, no. 10 (2016): 2513–20. http://dx.doi.org/10.1128/jcm.01066-16.

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Infection is an important complication in patients with hematologic malignancies or solid tumors undergoing intensive cytotoxic chemotherapy. In only 20 to 30% of the febrile neutropenic episodes, an infectious agent is detected by conventional cultures. In this prospective study, the performance of broad-range PCR coupled with electrospray ionization time of flight mass spectrometry (PCR/ESI-MS) technology was compared to conventional blood cultures (BC) in a consecutive series of samples from high-risk hematology patients. In 74 patients, BC and a whole-blood sample for PCR/ESI-MS (Iridica B

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Driver, Brandon R., Bryce P. Portier, Dina R. Mody, et al. "Next-Generation Sequencing of a Cohort of Pulmonary Large Cell Carcinomas Reclassified by World Health Organization 2015 Criteria." Archives of Pathology & Laboratory Medicine 140, no. 4 (2015): 312–17. http://dx.doi.org/10.5858/arpa.2015-0361-oa.

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The classification of pulmonary large cell carcinoma has undergone a major revision with the recent World Health Organization (WHO) 2015 Classification. Many large cell carcinomas are now reassigned to either adenocarcinoma with solid pattern or nonkeratinizing squamous cell carcinoma based on immunopositivity for adenocarcinoma markers or squamous cell carcinoma markers, respectively. Large cell carcinomas that are negative for adenocarcinoma and squamous cell carcinoma immunomarkers are now classified as large cell carcinoma with null immunohistochemical features (LCC-N). Although a few stud

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Zheng, Ruifang, Zhiwei Yin, Albert Alhatem, et al. "Epidemiologic Features of NSCLC Gene Alterations in Hispanic Patients from Puerto Rico." Cancers 12, no. 12 (2020): 3492. http://dx.doi.org/10.3390/cancers12123492.

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Targeted therapy has changed the paradigm of advanced NSCLC management by improving the survival rate of patients carrying actionable gene alterations using specific inhibitors. The epidemiologic features of these alterations vary among races. Understanding the racial differences benefits drug development, clinical trial design, and health resource allocation. Compared to Caucasian and Asian populations, current knowledge on Hispanic patients is less and no data of Hispanic patients from Puerto Rico have been reported. We retrieved and analyzed the demographic, clinical, and molecular data of

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33

Zancan, Matelda, Francesca Galdi, Fulvio Di Tonno, et al. "Evaluation of Cell-free DNA in Urine as a Marker for Bladder Cancer Diagnosis." International Journal of Biological Markers 24, no. 3 (2009): 147–55. http://dx.doi.org/10.1177/172460080902400304.

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The diagnosis and follow-up of bladder cancer are mainly based on cystoscopy, an invasive method which could be negative in case of flat malignancies such as carcinoma in situ. Other noninvasive diagnostic methods have not yet given satisfactory results. There is a need for a reliable yet noninvasive method for the detection of bladder cancer. Our aim was to investigate whether cell-free DNA quantified in urine (ucf-DNA) could be a useful marker for the diagnosis of bladder cancer. A standard urine test was performed in 150 naturally voided morning urine samples that were processed to obtain a

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Hogan, Catherine, Anthony T. Le, Justin Mak, Malaya Kumar. Sahoo, Tina Cowan, and Benjamin A. Pinksy. "1791. Novel Metabolomics Approach for the Diagnosis of Respiratory Viruses Directly from Nasopharyngeal Specimens." Open Forum Infectious Diseases 6, Supplement_2 (2019): S660. http://dx.doi.org/10.1093/ofid/ofz360.1654.

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Abstract Background Respiratory virus infections are important causes of morbidity and mortality among pediatric and adult patients. These viruses infect respiratory epithelial cells, where they may induce specific metabolite alterations. As a proof-of-concept, we investigate the novel use of liquid chromatography (LC) combined with quadrupole time-of-flight mass spectrometry (Q-TOF) for the study of host cell metabolite alterations to diagnose and differentiate respiratory viruses. Methods We studied nasopharyngeal swab samples positive for respiratory viruses by the eSensor Respiratory Viral

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35

Moniruzzaman, Mohammad, Mousumi Karmaker, Sadia Tasnim, et al. "Procalcitonin: A unique marker to evaluate the severity of sepsis among diabetic patients." Bangladesh Critical Care Journal 10, no. 1 (2022): 38–42. http://dx.doi.org/10.3329/bccj.v10i1.59202.

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Introduction: Diabetes mellitus (DM) is considered one of the largest emerging threats to health and bacterial infections are more frequent in diabetic patients causing sepsis. Several indicators have been proposed as new diagnostic tests to assess sepsis in hospitalized patients. Aim: This study aims was to compare the efficacy of Procalcitonin (PCT) and high sensitive C-reactive protein (hs-CRP) in the diagnosis of sepsis in diabetic patients. Methods: In this cross-sectional study total of 60 age and sex-matched diabetic patients above 18 years were randomly chosen with at least 2 SIRS (Sys

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Moniruzzaman, Mohammad, Mousumi Karmaker, Sadia Tasnim, et al. "Procalcitonin: A unique marker to evaluate the severity of sepsis among diabetic patients." Bangladesh Critical Care Journal 10, no. 1 (2022): 38–42. http://dx.doi.org/10.3329/bccj.v10i1.59202.

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Introduction: Diabetes mellitus (DM) is considered one of the largest emerging threats to health and bacterial infections are more frequent in diabetic patients causing sepsis. Several indicators have been proposed as new diagnostic tests to assess sepsis in hospitalized patients. Aim: This study aims was to compare the efficacy of Procalcitonin (PCT) and high sensitive C-reactive protein (hs-CRP) in the diagnosis of sepsis in diabetic patients. Methods: In this cross-sectional study total of 60 age and sex-matched diabetic patients above 18 years were randomly chosen with at least 2 SIRS (Sys

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Greaves, Wesley O., Shalini Verma, Tigist Bisrat, et al. "TP53 Mutation Is Rare In Primary Myelofibrosis." Blood 118, no. 21 (2011): 5241. http://dx.doi.org/10.1182/blood.v118.21.5241.5241.

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Abstract Abstract 5241 Introduction TP53 is the most frequently mutated tumor suppressor gene in human cancers and is usually associated with an aggressive disease course. TP53 mutation has been described in a variety of hematopoietic neoplasms, and has been suggested to play a role in leukemic transformation of myeloproliferative neoplasms (MPN). However, the incidence as well as the clinical and pathogenetic implications of TP53 mutation in each sub-category of MPN, including primary myelofibrosis, have not been described. In this study, we investigated the presence and potential clinical si

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Tancos, Z., J. Kobolak, A. Baji Gal, and A. Dinnyes. "266 IDENTIFICATION OF Oct-4 AND Nanog, THE TWO PLURIPOTENCY MARKER GENES IN RABBIT PRE-IMPLANTATION-STAGE EMBRYOS." Reproduction, Fertility and Development 18, no. 2 (2006): 240. http://dx.doi.org/10.1071/rdv18n2ab266.

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Several genes, including Oct-4 and Nanog, coordinate the embryogenesis of mammalian embryos. Whereas Oct-4 has an activator effect, the Nanog protein blocks the transcription of several genes in early stages; however, the product of these two genes appears parallel and directs early embryogenesis. The goal of this work was to isolate the Oct-4 and Nanog genes from rabbit, based on the sequences of other species published so far. The sequence of known genes has been analyzed, and primers have been designed based on similarity of sequences. Oocyte-to-blastocyt-stage embryos were collected from s

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Lijfering, Willem M., Irene D. Bezemer, Sverre C. Christiansen, et al. "A Replication Study of Gene Variants Associated with Venous Thrombosis. Results From a Population-Based Nested Case-Cohort Study." Blood 114, no. 22 (2009): 3985. http://dx.doi.org/10.1182/blood.v114.22.3985.3985.

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Abstract Abstract 3985 Poster Board III-921 Background Venous thrombosis has genetic and acquired risk factors, and it has been proposed that several risk factors are needed for the occurrence of the disease. The identification of common gene variants associated with venous thrombosis may improve the ability to predict the risk and understanding of this disease. In a recent study, we aimed to identify genetic variants that are associated with deep vein thrombosis in individuals aged younger than 70 years (JAMA 2008; 299:1306-14). Of nearly 20000 single nucleotide polymorphisms (SNPs) that were

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Peña, E., E. Olate, R. A. Chorbadjian, and I. M. Rosales. "First Report of Alfalfa mosaic virus Infection in Viburnum tinus in Chile." Plant Disease 95, no. 9 (2011): 1198. http://dx.doi.org/10.1094/pdis-05-11-0414.

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Viburnum tinus L., commonly known as laurustinus, is an ornamental shrub that is widely used as a garden plant and flower crop. V. tinus is popular because of its desirable characteristics such as evergreen foliage, tolerance to pruning, winter blooms, and its adaptation to cold temperate zones. It is also relatively easy to grow and is commonly used as a windbreak. Infection of this ornamental species by Alfalfa mosaic virus (AMV) has been associated with yellow mottling or variegated leaf coloring, including light green and white, and has been referred to as the “Viburnum Calico” (1,4). In A

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Coelho, L. A., R. Peres, F. G. Amaral, and J. Cipolla-Neto. "197 EXPRESSION OF MELATONIN-RELATED GENES IN RAT CUMULUS–OOCYTE COMPLEXES." Reproduction, Fertility and Development 25, no. 1 (2013): 247. http://dx.doi.org/10.1071/rdv25n1ab197.

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Melatonin is a hormone usually associated with the modulation of circadian rhythms and the regulation of seasonal reproductive function. There is evidence that melatonin acts directly on the regulation of ovary function. The mRNA expression of melatonin membrane receptors genes was detected in mammalian and non-mammalian ovaries. In spite of melatonin receptors and Asmt (limiting enzyme in melatonin biosynthesis) genes being present in cattle cumulus–oocyte complexes (COC), no information regarding rat COC has been reported. The aim of this study was to investigate the expression of melatonin

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Testen, A. L., E. K. Walsh, C. G. Taylor, S. A. Miller, and H. D. Lopez-Nicora. "First Report of Bloat Nematode (Ditylenchus dipsaci) Infecting Garlic in Ohio." Plant Disease 98, no. 6 (2014): 859. http://dx.doi.org/10.1094/pdis-11-13-1121-pdn.

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Bloat nematode, Ditylenchus dipsaci (Kühn) Filipjev (also known as stem and bulb nematode), is a key pest of garlic (Allium sativum) globally (1) as heavy infestations can lead to complete crop loss. Although not a major crop in Ohio, garlic is grown in diversified vegetable production systems. In July 2013, diseased garlic bulbs were received from a grower in Lorain County, OH, from a field with wide symptom distribution. Bulbs were discolored, exhibited splitting, and had basal plate damage including reduced roots. Nematodes were extracted for examination by placing bulb slices in water. Rec

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Stein, Robert C., Janet A. Dunn, John MS Bartlett, et al. "OPTIMA prelim: a randomised feasibility study of personalised care in the treatment of women with early breast cancer." Health Technology Assessment 20, no. 10 (2016): 1–202. http://dx.doi.org/10.3310/hta20100.

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BackgroundThere is uncertainty about the chemotherapy sensitivity of some oestrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancers. Multiparameter assays that measure the expression of several tumour genes simultaneously have been developed to guide the use of adjuvant chemotherapy for this breast cancer subtype. The assays provide prognostic information and have been claimed to predict chemotherapy sensitivity. There is a dearth of prospective validation studies. The Optimal Personalised Treatment of early breast cancer usIng Multiparameter Ana

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Širca, S., B. Geric Stare, P. Strajnar, G. Urek, and I. Miklic Lautar. "First Report of the Pale Potato Cyst Nematode Globodera pallida from Slovenia." Plant Disease 96, no. 5 (2012): 773. http://dx.doi.org/10.1094/pdis-01-12-0066-pdn.

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The potato cyst nematodes (PCN) Globodera rostochiensis (Woll.) Behrens and G. pallida (Stone) Behrens are considered the most important nematode threat to potato production worldwide, and they are subject to strict quarantine regulations in many countries. The first report of the PCN in Slovenia dates back to 1971, when a single cyst of G. rostochiensis was detected (3). In the last decade, G. rostochiensis was detected several times, mainly in the central and northern parts of the country (2). Interceptions of G. pallida in imported consignments of ware potato were made several times, but ha

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Moore, K., E. Wroclawska, J. M. Kramer, and S. L. Goicoa. "67 CELL TYPE AND CULTURE OVER TIME EFFECT DNA METHYLTRANSFERASE 1 EXPRESSION IN BOVINE DONOR FIBROBLAST CELLS." Reproduction, Fertility and Development 19, no. 1 (2007): 151. http://dx.doi.org/10.1071/rdv19n1ab67.

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Aberrant chromatin remodeling has been implicated in the low success rates achieved from cloned embryos. Following fertilization, DNA methylation within a normal embryo is rapidly reduced to a very low level and remains low until the 8–16 cell stage when DNA methylation once again increases. In contrast, the majority of cloned embryos fail to exhibit a similar methylation pattern. This may be due to somatic cell-associated DNMT1s keeping methylation high. However, attempts to chemically modify methylation patterns of donor cells prior to cloning have proven problematic. The objective of this s

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Eastwell, K. C., J. R. Glass, L. M. Seymour, and K. J. Druffel. "First Report of Infection of Poison Hemlock and Celery by Apium virus Y in Washington State." Plant Disease 92, no. 12 (2008): 1710. http://dx.doi.org/10.1094/pdis-92-12-1710c.

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A commercial field of celery (Apium graveolens var. dulce) cvs. Conquistador and Sabroso was planted with sets between 1 June and 10 July 2004 in Pierce County in western Washington (WA). In late August, many plants were stunted and showed chlorotic line patterns. One symptomatic plant and five nonsymptomatic plants were transferred to a greenhouse and grown at 22°C with supplemental lighting to extend day length to 16 h; foliage was trimmed back. The symptomatic plant and three nonsymptomatic plants developed a distinctive chlorotic line pattern when new foliage emerged in February. Two plant

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Kieft, Thomas L., Devyn Del Curto, Zoë Havlena, et al. "Potential for Mitigation of Cave Lampenflora Using Benzalkonium Chloride or UV-C." Geoheritage 15, no. 2 (2023). http://dx.doi.org/10.1007/s12371-023-00839-4.

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AbstractArtificial illumination in caves visited by tourists (“show caves”) gives rise to growth of photosynthetic biofilms, termed “lampenflora.” Besides being unsightly, these biofilms can damage speleothems, and thus finding a safe and effective means of controlling lampenflora is an important consideration in cave management. A variety of different physical and chemical means of biofilm mitigation have been proposed and tested. Here we tested benzalkonium chloride (BAC), a quaternary ammonium cationic detergent commonly used in pharmaceuticals and cosmetics, and germicidal UV light (UV-C)

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DuCHENE, HARVEY R. "Abstract: Origin and Mineralogy of Lechuguilla Cave, Carlsbad Caverns National Park, New Mexico." AAPG Bulletin 83 (1999) (1999). http://dx.doi.org/10.1306/00aa9b38-1730-11d7-8645000102c1865d.

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Ulbrich, Joseph, Nathaniel E. Jobe, Daniel S. Jones, and Thomas L. Kieft. "Cave Pools in Carlsbad Caverns National Park Contain Diverse Bacteriophage Communities and Novel Viral Sequences." Microbial Ecology 87, no. 1 (2024). https://doi.org/10.1007/s00248-024-02479-9.

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Abstract Viruses are the most abundant biological entities on Earth, and they play a critical role in the environment and biosphere where they regulate microbial populations and contribute to nutrient cycling. Environmental viruses have been the most studied in the ocean, but viral investigations have now spread to other environments. Here, viral communities were characterized in four cave pools in Carlsbad Caverns National Park to test the hypotheses that (i) viral abundance is ten-fold higher than prokaryotic cell abundance in cavern pools, (ii) cavern pools contain novel viral sequences, an

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Havlena, Zoë, Thomas L. Kieft, George Veni, Rodney D. Horrocks, and Daniel S. Jones. "Lighting Effects on the Development and Diversity of Photosynthetic Biofilm Communities in Carlsbad Cavern, New Mexico." Applied and Environmental Microbiology 87, no. 6 (2021). http://dx.doi.org/10.1128/aem.02695-20.

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Artificial lighting in caves visited by tourists (“show caves”) can stimulate photosynthetic algae and cyanobacteria, called “lampenflora,” which are unsightly and damage speleothems and other cave surfaces. The most common mitigation strategy employs bleach, but altering intensities and wavelengths of light might be effective and less harsh.

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