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1

Schaller, Bernhard J., ed. Imaging of Carotid Artery Stenosis. Vienna: Springer Vienna, 2007. http://dx.doi.org/10.1007/978-3-211-32509-4.

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2

Seemant, Chaturvedi, and Rothwell Peter M, eds. Carotid artery stenosis: Current and emerging treatments. Boca Raton: Taylor & Francis, 2005.

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3

Moussa, Issam. Asymptomatic Carotid Artery Stenosis: A Primer on Risk Stratification and Management. New York: Taylor & Francis Ltd., 2007.

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4

Jacqueline, Saw, ed. Handbook of complex percutaneous carotid intervention. Totowa, N.J: Humana Press, 2007.

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5

MD, Henry Michel, ed. Angioplasty and stenting of the carotid and supra-aortic trunks. London: Martin Dunitz, 2004.

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6

T, Meenan Richard, United States. Agency for Healthcare Research and Quality., and Oregon Health & Science University. Evidence-based Practice Center., eds. Effectiveness and cost-effectiveness of echocardiography and carotid imaging in the management of stroke. Rockville, MD: U.S. Dept. of Health and Human Services, Public Health Service, Agency for Healthcare Research and Quality, 2002.

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7

Thomas, Meenan Richard, United States. Agency for Healthcare Research and Quality., and Oregon Health & Science University. Evidence-based Practice Center., eds. Effectiveness and cost-effectiveness of echocardiography and carotid imaging in the management of stroke. Rockville, MD: U.S. Dept. of Health and Human Services, Public Health Service, Agency for Healthcare Research and Quality, 2002.

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8

Eugene, Zierler R., ed. Surgical management of cerebrovascular disease. New York: McGraw-Hill, Health Professions Division, 1995.

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9

Nadim, Al-Mubarak, ed. Carotid artery stenting: Current practice and techniques. Philadelphia: Lippincott Williams & Wilkins, 2004.

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10

E, Berry, National Co-ordinating Centre for HTA (Great Britain), and Health Technology Assessment Programme, eds. The cost-effectiveness of magnetic resonance angiography for carotid artery stenosis and peripheral vascular disease: A systematic review. Alton: Core Research on behalf of the NCCHTA, 2002.

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11

Chaturvedi, Seemant, and Peter Rothwell, eds. Carotid Artery Stenosis. CRC Press, 2005. http://dx.doi.org/10.1201/b14239.

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12

Chaturvedi, Seemant, and Peter M. Rothwell, eds. Carotid Artery Stenosis. CRC Press, 2005. http://dx.doi.org/10.3109/9780203025970.

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13

Rothwell, Peter M., and Seemant Chaturvedi. Carotid Artery Stenosis. Taylor & Francis Group, 2019.

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14

Green, Lori. Carotid Stenosis Assessment. Gulfcoast Ultrasound Institute, 2002.

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15

Hochman, Michael E. Carotid Endarterectomy for Asymptomatic Carotid Stenosis. Edited by SreyRam Kuy, Wayne Zhang, and Tze-Woei Tan. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199384075.003.0005.

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This chapter provides a summary of the landmark surgical study known as the ACST trial, which compared surgical versus nonsurgical treatment for asymptomatic carotid stenosis. Is carotid endarterectomy (CEA) beneficial in asymptomatic patients with severe carotid stenosis? Starting with that question, the chapter describes the basics of the study, including funding, year study began, year study was published, study location, who was studied, who was excluded, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, gives a summary and discusses implications, and concludes with a relevant clinical case involving vascular surgery.
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16

Amin, Hardik A. Carotid Endarterectomy for Symptomatic Carotid Stenosis. Edited by SreyRam Kuy, Wayne Zhang, and Tze-Woei Tan. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199384075.003.0006.

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This chapter provides a summary of the landmark surgical study known as the NASCET trial, which compared surgical versus nonsurgical treatment for patients with symptomatic carotid stenosis. The chapter describes the basics of the study, including funding, year study began, year study was published, study location, who was studied, who was excluded, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, gives a summary and discusses implications, and concludes with a relevant clinical case regarding vascular surgery.
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17

Moussa, Issam D., Tatjana Rundek, and JP Mohr, eds. Asymptomatic Carotid Artery Stenosis. CRC Press, 2007. http://dx.doi.org/10.3109/9780203089859.

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18

Lee, Christoph I. Carotid Artery Stenosis Screening. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190223700.003.0008.

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This chapter, found in the headache section of the book, provides a succinct synopsis of a key study examining the use of ultrasound for carotid artery stenosis screening in asymptomatic adults. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. Researchers reported that there is little evidence that the benefits of carotid endarterectomy, stenting, or intensification of medical therapy outweigh the risks among patients with asymptomatic carotid artery stenosis; the low prevalence of the disease and known harms associated with intervention limit the benefits of screening. In addition to outlining the most salient features of the study, a clinical vignette and imaging example are included in order to provide relevant clinical context.
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19

Yadav, Jay S., and Samir Kamedia. Carotid and Intracranial Stenosis. Informa Healthcare, 2007.

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20

Schaller, Bernhard. Imaging of Carotid Artery Stenosis. Springer Wien, 2014.

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21

Imaging of Carotid Artery Stenosis. Springer, 2007.

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22

Schaller, Bernhard. Imaging of Carotid Artery Stenosis. Springer London, Limited, 2007.

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23

Rothwell, Peter M., and Seemant Chaturvedi. Carotid Artery Stenosis: Current and Emerging Treatments. Taylor & Francis Group, 2005.

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24

Rothwell, Peter M., and Seemant Chaturvedi. Carotid Artery Stenosis: Current and Emerging Treatments. Taylor & Francis Group, 2005.

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25

Rothwell, Peter M., and Seemant Chaturvedi. Carotid Artery Stenosis: Current and Emerging Treatments. Taylor & Francis Group, 2005.

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26

Rothwell, Peter M., and Seemant Chaturvedi. Carotid Artery Stenosis: Current and Emerging Treatments. Taylor & Francis Group, 2005.

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27

Rothwell, Peter M., and Seemant Chaturvedi. Carotid Artery Stenosis: Current and Emerging Treatments. Taylor & Francis Group, 2005.

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28

Lee, Christoph I. Imaging Tests for Diagnosis of Carotid Artery Stenosis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190223700.003.0007.

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This chapter, found in the headache section of the book, provides a succinct synopsis of a key study examining the use of duplex ultrasound (DUS), magnetic resonance angiography (MRA), and digital subtraction angiography for diagnosing carotid artery stenosis. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. The study showed that both DUS and MRA are very accurate for detecting carotid artery occlusion; however, MRA is more accurate than DUS in diagnosing 70%–99% carotid artery stenosis. In addition to outlining the most salient features of the study, a clinical vignette and imaging example are included in order to provide relevant clinical context.
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29

S, Lee David, Jacqueline Saw, Sanjay Yadav, and Jose Exaire. Handbook of Complex Percutaneous Carotid Intervention. Humana, 2016.

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30

Schoolfield, Clint S., Wayne W. Zhang, and Tze-Woei Tan. Stenting versus Endarterectomy for Treatment of Carotid-Artery Stenosis. Edited by SreyRam Kuy, Wayne Zhang, and Tze-Woei Tan. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199384075.003.0007.

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This chapter provides a summary of the landmark CREST study that compared carotid endarterectomy (CEA) and carotid artery stenting (CAS) for patients with symptomatic or asymptomatic carotid artery stenosis. The study found that the combined overall rate of stroke, myocardial infarction (MI) or death between CEA and CAS did not differ significantly in symptomatic or asymptomatic patients. However, during the perioperative period, CAS was associated with an increased risk of stroke and CEA was associated with an increased risk of MI. The chapter describes the basics of the study, including funding, year study began, year study was published, study location, who was studied, who was excluded, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, gives a summary and discusses implications, and concludes with a relevant clinical case.
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31

(Editor), Issam Moussa, Tatjana Rundek (Editor), and Jay Preston Mohr (Editor), eds. Asymptomatic Carotid Artery Stenosis: A Primer on Risk Stratification and Management. Informa Healthcare, 2007.

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32

Mohr, J. P., Issam D. Moussa, and Tatjana Rundek. Asymptomatic Carotid Artery Stenosis: A Primer on Risk Stratification and Management. Taylor & Francis Group, 2007.

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33

Chaturvedi, Seemant, Christopher Bladin, Hege Ihle-Hansen, and Peter Kelly, eds. Emerging Areas in Extracranial Carotid Stenosis Evaluation and Management. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88976-036-7.

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34

Diethrich, Edward B., Michel Henry, and Antonios Polydorou. Carotid and Supra-Aortic Trunks: Diagnosis, Angioplasty and Stenting. Wiley & Sons, Incorporated, John, 2011.

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35

Diethrich, Edward B., Michel Henry, and Antonios Polydorou. Carotid and Supra-Aortic Trunks: Diagnosis, Angioplasty and Stenting. Wiley & Sons, Incorporated, John, 2011.

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36

Diethrich, Edward B., Michel Henry, and Antonios Polydorou. Carotid and Supra-Aortic Trunks: Diagnosis, Angioplasty and Stenting. Wiley & Sons, Limited, John, 2011.

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37

Diethrich, Edward B., Michel Henry, and Antonios Polydorou. Carotid and Supra-Aortic Trunks: Diagnosis, Angioplasty and Stenting. Wiley & Sons, Incorporated, John, 2011.

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38

The Carotid and Supra-Aortic Trunks: Diagnosis, Angioplasty and Stenting. Wiley-Interscience, 2011.

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39

(Editor), Seemant Chaturvedi, and Peter M. Rothwell (Editor), eds. Carotid Artery Stenosis: Current and Emerging Treatments (Neurological Disease and Therapy). Informa Healthcare, 2005.

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40

Ellis, Jason A., and E. Sander Connolly. Vascular Biology of Cerebral Ischemia. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0107.

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Carotid stenosis may be treated by carotid endarterectomy (CEA) or carotid artery stenting (CAS). Moderate asymptomatic carotid stenosis (50%-70%) is associated with a low risk of ischemic stroke and does not warrant treatment. The severe stenosis (>70%) population sees a marginal benefit in seen with CEA. In the Asymptomatic Carotid Atherosclerosis Study, authors concluded that for patients with less than 60% stenosis, a 5.9% absolute risk reduction was obtained over 5 years with CEA compared with maximum medical management (11 vs. 5.1%).
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41

Current Status of Carotid Bifurcation Angioplasty and Stenting. Informa Healthcare, 2001.

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42

Practical Carotid Artery Stenting. Springer, 2008.

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43

(Editor), Michel Henry, Takao Ohki (Editor), Antonio Polydorou (Editor), Kyriakos Strigaris (Editor), and Dimitrios Kiskinis (Editor), eds. Angioplasty and Stenting of the Carotid and Supra Aortic Trunks. Informa Healthcare, 2004.

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44

Chong, Ji Y., and Michael P. Lerario. Detected Bruit. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190495541.003.0009.

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Carotid stenosis is a risk factor for stroke. Revascularization of high-grade asymptomatic carotid stenosis in select patients can lower the risk of incident stroke. Endarterectomy and stenting are both associated with periprocedural risk. Risks and benefits need to be evaluated carefully before proceeding with any intervention. Certain patient demographic and clinical characteristics, such as female gender, may reduce the benefits of surgery and influence treatment decisions.
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45

Chong, Ji Y., and Michael P. Lerario. Obstructed Flow. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190495541.003.0011.

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Patients with symptomatic carotid stenosis benefit from revascularization. The risk of recurrent stroke is highest during the early period after a transient ischemic attack or stroke. Carotid endarterectomy and carotid stenting are options for treatment and should be considered within the first 2 weeks if feasible.
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46

Al-Mubarak, Nadim, Gary S. Roubin, Sriram S. Iyer, and Jiri J. Vitek. Carotid Artery Stenting: Current Practice and Techniques. Lippincott Williams & Wilkins, 2004.

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47

Markus, Hugh, Anthony Pereira, and Geoffrey Cloud. Vascular anatomy and stroke syndromes. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198737889.003.0003.

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Determining the arterial territory in which a stroke occurs is important in diagnosis. It also has major implications for management; for example, treatment of a symptomatic carotid stenosis differs greatly to that of an incidental stenosis in a patient with posterior circulation stroke. This chapter describes the arterial supply of the brain and links it to stroke syndromes that present acutely to the stroke clinician. It also covers the venous supply which is important in understanding cerebral venous thrombosis.
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48

U.S. Department of Health and Human Services. Screening for Asymptomatic Carotid Artery Stenosis: A Systematic Review and Meta-Analysis for the U.S. Preventive Services Task Force. CreateSpace Independent Publishing Platform, 2015.

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49

Chong, Ji Y., and Michael P. Lerario. Puff of Smoke. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190495541.003.0023.

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Moyamoya is a rare cause of stroke caused by progressive distal carotid occlusion. Children and adults may be affected, but it is more common in Asian populations, particularly in patients presenting with intracranial hemorrhage. Angiographic findings of distal internal carotid artery stenosis with lenticulostriate or choroidal neocollaterals are important in the diagnosis of moyamoya disease. A similar pathophysiological state to moyamoya disease is associated with several clinical conditions, some of which are acquired and some of which have a genetic etiology. Treatment is with surgical revascularization, which can reduce both ischemic and hemorrhagic complications.
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50

Markus, Hugh, Anthony Pereira, and Geoffrey Cloud. Secondary prevention of stroke. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198737889.003.0010.

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In the secondary prevention of stroke chapter the case is made for preventing recurrent stroke by targeted evidence-based intervention based on the aetiological cause of stroke. Lifestyle measures such as smoking cessation as well as pharmacological prevention strategies are discussed. Blood pressure treatment, lipid lowering, and antiplatelet therapy are all examined. Since the last edition there has been a major advance in the stroke prevention treatment of atrial fibrillation with the licensing of new anticoagulant agents and the evidence for their use is reviewed. Surgical and endovascular interventions for extracranial and intracranial stenosis are also outlined, including carotid endarterectomy, carotid stenting, extracranial-intracranial bypass, and intervention for vertebral artery disease.
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