Academic literature on the topic 'Carrageenan-induced paw edema'

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Journal articles on the topic "Carrageenan-induced paw edema"

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Liang, Jia-Li, Jia-Zhen Wu, Yu-Hong Liu та ін. "Patchoulene Epoxide Isolated from Patchouli Oil Suppresses Acute Inflammation through Inhibition of NF-κB and Downregulation of COX-2/iNOS". Mediators of Inflammation 2017 (2017): 1–14. http://dx.doi.org/10.1155/2017/1089028.

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According to the GC-MS analysis, compositional variation was observed between samples of patchouli oil, of which an unknown compound identified as patchoulene epoxide (PAO) was found only in the long-stored oil, whose biological activity still remains unknown. Therefore, the present study aimed to evaluate the potential anti-inflammatory activity with three in vivo inflammatory models: xylene-induced ear edema, acetic acid-induced vascular permeability, and carrageenan-induced paw edema. Further investigation into its underlying mechanism on carrageenan-induced paw edema was conducted. Results
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Li, Chu-Wen, Xiao-Li Wu, Xiao-Ning Zhao, et al. "Anti-Inflammatory Property of the Ethanol Extract of the Root and Rhizome ofPogostemon cablin(Blanco) Benth." Scientific World Journal 2013 (2013): 1–12. http://dx.doi.org/10.1155/2013/434151.

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The aim of this study was to investigate the anti-inflammatory property of the ethanol extract of the root and rhizome ofPogostemon cablin(ERP). The anti-inflammatory effect was evaluated using four animal models including xylene-induced mouse ear edema, acetic acid-induced mouse vascular permeability, carrageenan-induced mouse pleurisy, and carrageenan-induced mouse hind paw edema. Results indicated that oral administration of ERP (120, 240, and 480 mg/kg) significantly attenuated xylene-induced ear edema, decreased acetic acid-induced capillary permeability, inhibited carrageenan-induced neu
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Beloeil, Hélène, Zaid Ababneh, Richard Chung, David Zurakowski, Robert V. Mulkern, and Charles B. Berde. "Effects of Bupivacaine and Tetrodotoxin on Carrageenan-induced Hind Paw Inflammation in Rats (Part 1)." Anesthesiology 105, no. 1 (2006): 128–38. http://dx.doi.org/10.1097/00000542-200607000-00022.

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Background Local anesthetics exert antiinflammatory actions. To elucidate potential mechanisms, the authors examined effects of bupivacaine or tetrodotoxin, administered to rats by ipsilateral or contralateral sciatic blockade or systemically, on carrageenan-induced hind paw hyperalgesia, edema, and stimulated cytokine production in circulating blood cells. Methods Twelve groups of rats (n = 9-12) received injections in three sites: (1) right or left hind paw (carrageenan or saline), (2) left sciatic block, and (3) systemically (subcutaneously in the upper back). Sciatic and systemic injection
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Yanti, D. Sabella, A. W. Gunawan, and B. W. Lay. "Clitoria ternatea anthocyanin extract suppresses inflammation in carrageenaninduced rat paw edema via down-regulating genes of phosphoinositide 3-kinase signaling pathway." Food Research 4, no. 4 (2020): 1357–62. http://dx.doi.org/10.26656/fr.2017.4(4).028.

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Inflammation is characterized by an increase in vascular permeability leading to edema formation. Phosphoinositide 3-kinase (PI3K) signaling pathway plays the main role to regulate several key events in the inflammatory response to damage and infection. Our previous in silico study showed that anthocyanin and ternatin flavonoids may offer antiinflammatory potential via molecular docking model. Here, we explored whether Clitoria ternatea anthocyanin extract (CTA) had protective activity against inflammation via regulating gene expression related to PI3Ks in rat edema. CTA was extracted in metha
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Cordaro, Marika, Rosalba Siracusa, Roberta Fusco, et al. "Cashew (Anacardium occidentale L.) Nuts Counteract Oxidative Stress and Inflammation in an Acute Experimental Model of Carrageenan-Induced Paw Edema." Antioxidants 9, no. 8 (2020): 660. http://dx.doi.org/10.3390/antiox9080660.

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Background: Anacardium occidentale L. is a medicinal plant with powerful anti-oxidative and anti-inflammatory properties. Acute inflammatory events cause tissue alterations, decrease of anti-oxidative endogenous enzymes such as superoxide dismutase, catalase and glutathione, neutrophils infiltration, increase in the activities of myeloperoxidase, malondialdehyde, and pro-inflammatory release. Methods: Paw edema was induced by subplantar injection of carrageenan into the right hind paw in rats, but 30 min before a group of animals were orally treated with 100 mg/kg of cashew nuts to evaluate th
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Wu, Xiao-Li, Chu-Wen Li, Hai-Ming Chen, et al. "Anti-Inflammatory Effect of Supercritical-Carbon Dioxide Fluid Extract from Flowers and Buds ofChrysanthemum indicumLinnén." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–13. http://dx.doi.org/10.1155/2013/413237.

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The aim of this study was to analyze the chemical composition and investigate the anti-inflammatory property of the supercritical-carbon dioxide extract from flowers and buds ofC. indicum(CISCFE). The anti-inflammatory effect was evaluated in four animal models including xylene-induced mouse ear edema, acetic acid-induced mouse vascular permeability, carrageenan-induced mouse hind paw edema, and cotton pellet-induced rat granuloma formation. The results indicated that CISCFEsignificantly attenuated xylene-induced ear edema, decreased acetic acid-induced capillary permeability, reduced carragee
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Wan, Yu-Jui Yvonne, and Mostafa Z. Badr. "Inhibition of Carrageenan-Induced Cutaneous Inflammation by PPAR Agonists Is Dependent on Hepatocyte-Specific Retinoid X ReceptorAlpha." PPAR Research 2006 (2006): 1–6. http://dx.doi.org/10.1155/ppar/2006/96341.

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It has been proposed that PPAR-dependent, accelerated catabolism of proinflammatory mediators may contribute to the fast resolution of inflammation. Because retinoid X receptors are obligate heterodimer partners of PPARs, we investigated the impact of deleting hepatocyte-specific RXRαon the antiedema effect of PPAR agonists. In wild-type mice (WT), pretreatment with the PPARαagonist perfluorooctanoic acid diminished carrageenan-induced paw edema by66±10%. This effect was essentially absent (13±8%) in hepatocyte-specific RXRα-deficient mice. Similarly, pretreatment of WT mice with the PPARδagon
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Vandana, Jyoti, Gupta A. K, and Alok Mukerjee. "PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF AERIAL PART EXTRACTS OF PLANTAGO MAJOR L." Asian Journal of Pharmaceutical and Clinical Research 10, no. 9 (2017): 307. http://dx.doi.org/10.22159/ajpcr.2017.v10i9.20031.

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Objective: This study aims to perform phytochemical screening and investigate anti-inflammatory activity of extract from aerial part of the plant Plantago major L.Methods: Preliminary phytochemical screening of plant extract was carried out using standard qualitative procedures and anti-inflammatory activity was evaluated using carrageenan-induced paw edema model in male Wistar albino rats using plethysmometer. Diclofenac sodium (10 mg/kg, b.w.) was used as standard drug.Results: Preliminary phytochemical screening of the different extracts revealed that they were rich in secondary metabolite
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Lai, Shang-Chih, Wen-Huang Peng, Shun-Chieh Huang, et al. "Analgesic and Anti-Inflammatory Activities of Methanol Extract fromDesmodium triflorumDC in Mice." American Journal of Chinese Medicine 37, no. 03 (2009): 573–88. http://dx.doi.org/10.1142/s0192415x09007065.

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In this study, we evaluated the analgesic effect of methanol extract from Desmodium triflorum DC (MDT) by using animal models of acetic acid-induced writhing response and formalin test. The anti-inflammatory effect of MDT was investigated by λ-carrageenan-induced paw edema in mice. In order to study the anti-inflammatory mechanism of MDT, we detected the activities of glutathione peroxidase (GPx) and glutathione reductase (GRd) in the liver, the levels of interleukin-1β (IL-1β), tumor necrosis factor (TNF-α), malondialdehyde (MDA) and nitric oxide (NO) in the edema paw tissue. In the analgesic
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Ko, Yu-Jen, Tsung-Chun Lu, Susumu Kitanaka, et al. "Analgesic and Anti-Inflammatory Activities of the Aqueous Extracts from Three Flemingia Species." American Journal of Chinese Medicine 38, no. 03 (2010): 625–38. http://dx.doi.org/10.1142/s0192415x1000810x.

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I-Tiao-Gung has long been used in the Kinmen area of Taiwan as an anti-inflammatory agent for the treatment of rheumatic illness. The roots of Flemingia lineata (FL), Flemingia macrophylla (FM) and Flemingia prostrata (FP) are also used as I-Tiao-Gung in the Taiwan markets. In the present study, we investigated the analgesic effect of aqueous extracts of Flemingia lineata (FL), Flemingia macrophylla (FM), and Flemingia prostrata (FP) by acetic acid-induced writhing response, formalin test, and the anti-inflammatory effect of FM, FL and FP by λ-carrageenan-induced paw edema in mice. We also det
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Dissertations / Theses on the topic "Carrageenan-induced paw edema"

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Wipa, Tanasomwang Jutamaad Satayavivad. "The screening of anti-inflammatory action of Clinacanthus nutans (Burm. f.) Lindau : a critical evaluation of carrageenan-induced hind paw edema model /." Abstract, 1986. http://mulinet3.li.mahidol.ac.th/thesis/2529/29E-Wipa-T.pdf.

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CHLASTÁKOVÁ, Adéla. "Zavedení a optimalizace \kur{in vivo} modelů zánětu a jejich využití pro funkční analýzu inhibitorů proteáz z klíštěcích slin." Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-262676.

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Two murine models of acute inflammation, namely thioglycollate-induced peritonitis and carrageenan-induced paw edema, were optimized using non-steroidal anti-inflammatory drug indomethacin and corticosteroid dexamethasone. During the optimization phase, the presence of neutrophils, monocytes, macrophages, eosinophils, B cells and T cells in the peritoneal cavity at various time points after injection of thioglycollate medium was assessed via multicolor flow cytometry. Moreover, two different thioglycollate media (suppliers BD and Sigma-Aldrich) were compared for their ability to induce an infl
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