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Relevant bibliographies by topics / Carvedilol phosphate

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Academic literature on the topic 'Carvedilol phosphate'

Author: Grafiati

Published: 4 June 2025

Last updated: 15 July 2025

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Journal articles on the topic "Carvedilol phosphate"

1

Vishakha, Dhananjay Jagtap. "Development and Evaluation of Buccal Film of Carvedilol Phosphate." International Journal of Research and Review 7, no. 5 (2020): 277–87. https://doi.org/10.5281/zenodo.3938707.

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The present study was undertaken to develop and evaluate buccal films of Carvedilol phosphate with an aim of improving patient compliance. Ease of administration with fast release of the drug was anticipated as the buccal films were prepared by using novel film forming agent obtained from natural source. Carvedilol phosphate buccal films were prepared by natural film former obtained from mucilage of Plantago ovata husk by solvent casting method. The films were evaluated for thickness uniformity, weight variation, surface pH, folding endurance, drug content uniformity, swelling index, disintegr

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2

Sopyan, Iyan, Wuri Ariestika Sari, Sandra Megantara, and Taofik Rusdiana. "Solubility enhancement of carvedilol by multicomponent crystal approach using glycine and arginine as coformers." Pharmacia 70, no. 4 (2023): 1479–86. http://dx.doi.org/10.3897/pharmacia.70.e112271.

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A Carvedilol is a member of BCS class II, it has a low solubility and bioavailability. This work intends to increase the solubility of carvedilol using a multicomponent crystal method. Based on in silico investigations showed that carvedilol-arginine formed one hydrogen bond and carvedilol-glycine formed two hydrogen bonds. Compared to the solubility of pure carvedilol, CVD: GLY multicomponent crystal ratios of 1:1, 1:2, and 2:1 resulted in increases in solubility of 1.9 times, 2.6 times, and 2.5 times respectively. The solubility of the multicomponent crystals in the CVD:ARG however, did not

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3

Sopyan, Iyan, Sari Wuri Ariestika, Sandra Megantara, and Taofik Rusdiana. "Solubility enhancement of carvedilol by multicomponent crystal approach using glycine and arginine as coformers." Pharmacia 70, no. (4) (2023): 1479–86. https://doi.org/10.3897/pharmacia.70.e112271.

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Abstract:

A Carvedilol is a member of BCS class II, it has a low solubility and bioavailability. This work intends to increase the solubility of carvedilol using a multicomponent crystal method. Based on in silico investigations showed that carvedilol-arginine formed one hydrogen bond and carvedilol-glycine formed two hydrogen bonds. Compared to the solubility of pure carvedilol, CVD: GLY multicomponent crystal ratios of 1:1, 1:2, and 2:1 resulted in increases in solubility of 1.9 times, 2.6 times, and 2.5 times respectively. The solubility of the multicomponent crystals in the CVD:ARG however, did not

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4

Chernyshev, Vladimir V., Alexandre A. Machula, Sergei Yu Kukushkin, and Yurii A. Velikodny. "Carvedilol dihydrogen phosphate hemihydrate: a powder study." Acta Crystallographica Section E Structure Reports Online 65, no. 8 (2009): o2020—o2021. http://dx.doi.org/10.1107/s1600536809029353.

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5

Shah, Ritesh, Sachin Patel, Hetal Patel, Sonia Pandey, Shailesh Shah, and Dinesh Shah. "Development and validation of dissolution method for carvedilol compression-coated tablets." Brazilian Journal of Pharmaceutical Sciences 47, no. 4 (2011): 899–906. http://dx.doi.org/10.1590/s1984-82502011000400027.

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The present study describes the development and validation of a dissolution method for carvedilol compression-coated tablets. Dissolution test was performed using a TDT-06T dissolution apparatus. Based on the physiological conditions of the body, 0.1N hydrochloric acid was used as dissolution medium and release was monitored for 2 hours to verify the immediate release pattern of the drug in acidic pH, followed by pH 6.8 in citric-phosphate buffer for 22 hours, to simulate a sustained release pattern in the intestine. Influences of rotation speed and surfactant concentration in medium were eval

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6

Ashok, Kumar J., S. Ramkanth, Prabu S. Lakshmana, and V. Gopal. "Enhancement of Saturation Solubility and In Vitro Dissolution of Carvedilol Nanoparticles by High Pressure Homogenization Technique." International Journal of Current Pharmaceutical Review and Research 6, no. 6 (2015): 269–73. https://doi.org/10.5281/zenodo.12685687.

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The objective of the work was to enhance the saturation solubility and in vitro dissolution of poorly soluble (BCS Class II)drug, Carvedilol by high pressure homogenization technique. Carvedilol nanoparticles were prepared by emulsiondiffusion followed by high pressure homogenization (HPH) technique with stabilizers. The prepared nanoparticle evaluatedfor its physicochemical properties, morphology, saturation solubility and in vitro dissolution study. The Carvedilolnanoparticles were prepared in a spherical shape and the size range of 120 nm to 300 nm. Carvedilol nanoparticles observedmaximum

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7

Abdel kawy, Hala Salah. "Low-dose carvedilol protects against acute septic renal injury in rats during the early and late phases." Canadian Journal of Physiology and Pharmacology 93, no. 6 (2015): 443–50. http://dx.doi.org/10.1139/cjpp-2014-0516.

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Recent findings from septic acute renal injury studies have implicated the mitochondrion as an important factor in kidney injury, and that increased sympathetic nerve activity may contribute to the induction of organ failure. This study investigated the impact of a nondepressor dose of carvedilol, which is a beta-adrenoreceptor antagonist with antioxidant activity, on septic renal injury induced in rats with cecal ligation and puncture (CLP). Three groups of rats were studied. The first group was the sham-operated control. The other 2 groups of rats underwent CLP, and were administered either

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8

M C, Sreekanth, Anusha Ajayakumar, and K. Santhi. "FORMULATION AND EVALUATION OF BUCCAL PATCHES OF CARVEDILOL PHOSPHATE." International Research Journal of Pharmacy 7, no. 8 (2016): 22–27. http://dx.doi.org/10.7897/2230-8407.07892.

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9

Ye, Li, Takayuki Furuishi, Takefumi Yamashita, and Etsuo Yonemochi. "Characterization and Crystal Structural Analysis of Novel Carvedilol Adipate and Succinate Ethanol-Solvated Salts." Molecules 29, no. 19 (2024): 4704. http://dx.doi.org/10.3390/molecules29194704.

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Two ethanol-solvated adipate and succinate salts of carvedilol (CVD), a Biopharmaceutics Classification System class 2 drug, were synthesized by crystallizing ethanol with adipic acid (ADP) and succinic acid (SUA). Proton transfer from ADP and SUA to CVD and the presence of ethanol in the two novel compounds were confirmed using powder X-ray diffraction, Fourier transform infrared spectroscopy, differential scanning calorimetry, thermogravimetric analysis, and single-crystal X-ray diffraction measurements. The two novel ethanol-solvated salts exhibited enhanced solubility and dissolution rates

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10

Sip, Szymon, Natalia Rosiak, Andrzej Miklaszewski, Patrycja Talarska, Ewa Dudziec, and Judyta Cielecka-Piontek. "Amorphous Form of Carvedilol Phosphate—The Case of Divergent Properties." Molecules 26, no. 17 (2021): 5318. http://dx.doi.org/10.3390/molecules26175318.

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The amorphous form of carvedilol phosphate (CVD) was obtained as a result of grinding. The identity of the obtained amorphous form was confirmed by powder X-ray diffraction (PXRD), different scanning calorimetry (DSC), and FT-IR spectroscopy. The process was optimized in order to obtain the appropriate efficiency and time. The crystalline form of CVD was used as the reference standard. Solid dispersions of crystalline and amorphous CVD forms with hydrophilic polymers (hydroxypropyl-β-cyclodextrin, Pluronic® F-127, and Soluplus®) were obtained. Their solubility at pH 1.2 and 6.8 was carried out

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Books on the topic "Carvedilol phosphate"

1

Blokdijk, G. J. Carvedilol Phosphate; A Complete Guide. CreateSpace Independent Publishing Platform, 2018.

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