Dissertations / Theses on the topic 'Cashin'
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KIM, EUN KYUNG. "PATTERN ANALYSIS ON THE WORKS OF BONNIE CASHIN FROM THE 1960S TO THE 1970S." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1021996954.
Full textBute, Martha Jane. "Bonnie Cashin connecting the designer to the designed garment through a material culture analysis of five examples of her work, 1962-1975 /." [Ames, Iowa : Iowa State University], 2007.
Find full textWeng, Yi-Lan. "The Cytoplasmic Adaptor Protein Caskin Participates in LAR-Mediated Motor Axon Guidance." Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1301673851.
Full textPost, Antonie E. [Verfasser]. "Fractionation of bovine casein and enrichment of functional casein peptides / Antonie E. Post." München : Verlag Dr. Hut, 2012. http://d-nb.info/1023435446/34.
Full textPost, Antonie [Verfasser]. "Fractionation of bovine casein and enrichment of functional casein peptides / Antonie E. Post." München : Verlag Dr. Hut, 2012. http://d-nb.info/1023435446/34.
Full textShammet, Khalid M. "Proteolytic Activity of Some Milk-Clotting Enzymes on K-casein and K-casein Macropeptide." DigitalCommons@USU, 1989. https://digitalcommons.usu.edu/etd/5371.
Full textZhou, Shuting. "Casein-phenolic interactions in food." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103772.
Full textLes interactions protéine-phénols sont courantes dans les aliments. Les études rapportent que ces interactions affectent les propriétés nutritionnelles et fonctionnelles des aliments. Les objectifs de cette recherche étaient d'étudier les interactions caséine-acides phénols dans un système modèle et dans un produit transformé à base de chocolat. Les interactions caséine-acides phénols ont été induites par la chaleur suite à une incubation de la caséine avec de l'acide protocatéchique ou de l'acide p-coumarique à 55 ℃ (pH 7, 2 h); les caséines ont été isolés du chocolat au lait et chocolat blanc en précipitant les caséines à son point isoélectrique (pH 4,6). Les complexes à base de caséine-phénolique ont été identifiés par électrophorèse en gel de polyacrylamide (non dénaturante et SDS-PAGE) et par la chromatographie en phase liquide à haute performance en phase inversée (CLHP-PI). Le degré d'hydrolyse des complexes caséine-phénoliques a été étudié par hydrolyse tryptique; l'électrophorèse en gel de polyacrylamide contenant du laurylsulfate de sodium (SDS-PAGE) et la chromatographie en phase liquide à haute performance en phase inversée (CLHP-PI) ont servi à identifier les hydrolysats des complexes à base de caséine-phénolique. Le contenu en phénols totaux du chocolat au lait d'origine et sans gras et de la caséine isolée de chocolat au lait (1,905, 1,644 et 1,018 mg / g respectivement) était plus élevé que celui du chocolat blanc original et sans gras et de la caséine isolée de chocolat blanc (1.678, 0.723 et 0,000 mg / g respectivement), respectivement. Les résultats de la chromatographie non dénaturante et SDS-PAGE ont révélé que les interactions caséine-phénols ont été induites par une incubation à la chaleur et sont survenues pendant le procédé du chocolat au lait; des changements mineurs dans la migration des fractions de caséine et de l'agrégation de sous-unités de caséine ont été observés après une incubation à la chaleur de la caséine avec de l'acide protocatéchique et dans la caséine isolée de chocolat au lait; il n'y a pas de changement observé avec les électrophérogrammes non dénaturante et SDS-PAGE après que la caséine ait été incubée avec de l'acide p-coumarique ni avec la caséine isolée à partir de chocolat blanc. L'hydrolyse in vitro de la caséine de contrôle (C), du complexe caséine-acide protocatéchique (CPA), du complexe caséine-acide p-coumarique (CCA), de la caséine isolée du chocolat au lait (CMC) et de la caséine isolée du chocolat blanc (CWC) par la trypsine ont montré un degré d'hydrolyse de 19,3%, 18,6%, 17,7%, 10,4% et 17,8% respectivement; SDS-PAGE a révélé que les trois principales fractions de caséine α-, β- et κ-caséine dans la caséine contrôle, le complexe caséine-acide protocatéchique, le complexe caséine-acide p-coumarique et la caséine isolée du chocolat au lait et du chocolat blanc ont été hydrolysées. L'acide protocatéchique et l'acide p-coumarique ont affecté le profil en peptides de la caséine; le profil en peptides de la caséine isolée de chocolat au lait a été affecté par les composés phénoliques.
Oommen, Bonney S. "Casein Supramolecules: Structure and Coagulation Properties." DigitalCommons@USU, 2004. https://digitalcommons.usu.edu/etd/5518.
Full textNaressi, Bruna Cristina Machado. "Análise comparativa de genes das caseínas de búfalo /." Jaboticabal, 2015. http://hdl.handle.net/11449/123663.
Full textCoorientador: Nedenia Bonvinos Stafuzza
Banca: Rodrigo Pelicioni Savegnago
Banca: Paola Jocelan Scarin Provazzi
Resumo: Dentre as proteínas do leite, as caseínas (alfa-s1, alfa-s2, beta- e kapa-caseína) assumem papel de destaque devido ao alto valor nutritivo e às características físico-químicas que favorecem a fabricação de derivados do leite. Essas proteínas são codificadas pelos genes CSN1S1, CSN1S2, CSN2 e CSN3. A fim de realizar análise comparativa dos genes das caseínas de búfalo, o presente trabalho teve como objetivo a identificação, caracterização e sequenciamento de clones da biblioteca genômica de búfalo, visando analisar a estrutura molecular de genes das caseínas. Dentre os 33.792 clones avaliados, foram identificados dois clones positivos para genes das caseínas, um para o gene CSN1S1 (clone A/2) e outro para o gene CSN3 (clone L/8). Na sequência de DNA obtida a partir do clone A/2, foram identificados os genes CSN1S1 inteiro e CSN2 parcial, enquanto que nas sequências de DNA do clone L/8 identificou-se o gene CSN3 partial. O gene CSN1S1 apresentou 17.008 bp organizados em 19 éxons com tamanhos variando de 24 bp a 380 bp e 18 íntrons com tamanhos de 90 bp a 1.710 bp. As análises comparativas revelaram que os éxons e íntrons desse gene apresentaram conservação acima de 85% entre búfalo e boi. As porções do gene CSN2 identificadas incluíram o éxon 9 e parte do íntron 8, os quais mostraram conservação acima de 98% com as sequências correspondentes em boi. Já as sequências parciais do gene CSN3 abrangeram parte dos íntrons 2 e 3 e o íntron 4 completo, além dos éxons 3, 4 e 5. Estas sequências apresentaram conservação acima de 94% com as correspondentes em boi. As análises de identificação de sequências repetitivas mostraram que 43,83% e 44,98% das sequências de DNA do clone A/2 e L/8, respectivamente, são representadas por elementos retrotransposons. Nas análises comparativas, tanto o gene CSN1S1 quanto o gene CSN3 parcial apresentaram sequências repetitivas búfalo específicas. A sequência...
Abstract: Among milk proteins, the caseins (alpha-s1, alpha-s2, beta- and kappa-casein) play a crucial role considering their high nutritional value and physicochemical characteristics which contribute to the manufacture of dairy products. These proteins are encoded by the CSN1S1, CSN1S2, CSN2 and CSN3 genes, respectively. In order to analyze the buffalo casein genes and compare the sequences with other species, the goal of the present study was to identify, characterize and sequence clones from a buffalo genomic library. A total of 33,792 clones were evaluated, and two clones were identified as positive, one for the CSN1S1 gene (clone A/2) and other for the CSN3 gene (clone L/8). The DNA sequence from clone A/2 identified the whole CSN1S1 and a partial sequence from the CSN2 genes. The DNA sequence from clone L/8 revealed a partial sequence from the CSN3 gene. The CSN1S1 gene presented a total of 17,008 bp organized in 19 exons ranging from 24 bp to 380 bp and 18 introns ranging from 90 bp to 1,710 bp. Comparative analysis showed sequence conservation higher than 85% on exons and introns of the CSN1S1 gene when compared with the cattle gene sequence. The partial sequence from the CSN2 gene included exon 9 and part of intron 8, with conservation higher than 98% when compared with the cattle sequence. The partial sequences of the CSN3 gene included parts of the introns 2 and 3, the whole sequence of intron 4 and exons 3, 4 and 5. These sequences showed conservation higher than 94% with cattle. The identification of repetitive sequences showed that 43.83% of DNA sequence from clone A/2 and 44,98% from clone L/8 were represented by retrotransposable elements. Further comparative analysis showed buffalo specific repetitive sequences in the CSN1S1 gene and the partial CSN3 gene with when compared with other bovids species. The coding sequence of the buffalo CSN1S1 gene showed 98%, 93%, and 90% of identity with the correspondent sequences in cattle ...
Mestre
Naressi, Bruna Cristina Machado [UNESP]. "Análise comparativa de genes das caseínas de búfalo." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/123663.
Full textDentre as proteínas do leite, as caseínas (alfa-s1, alfa-s2, beta- e kapa-caseína) assumem papel de destaque devido ao alto valor nutritivo e às características físico-químicas que favorecem a fabricação de derivados do leite. Essas proteínas são codificadas pelos genes CSN1S1, CSN1S2, CSN2 e CSN3. A fim de realizar análise comparativa dos genes das caseínas de búfalo, o presente trabalho teve como objetivo a identificação, caracterização e sequenciamento de clones da biblioteca genômica de búfalo, visando analisar a estrutura molecular de genes das caseínas. Dentre os 33.792 clones avaliados, foram identificados dois clones positivos para genes das caseínas, um para o gene CSN1S1 (clone A/2) e outro para o gene CSN3 (clone L/8). Na sequência de DNA obtida a partir do clone A/2, foram identificados os genes CSN1S1 inteiro e CSN2 parcial, enquanto que nas sequências de DNA do clone L/8 identificou-se o gene CSN3 partial. O gene CSN1S1 apresentou 17.008 bp organizados em 19 éxons com tamanhos variando de 24 bp a 380 bp e 18 íntrons com tamanhos de 90 bp a 1.710 bp. As análises comparativas revelaram que os éxons e íntrons desse gene apresentaram conservação acima de 85% entre búfalo e boi. As porções do gene CSN2 identificadas incluíram o éxon 9 e parte do íntron 8, os quais mostraram conservação acima de 98% com as sequências correspondentes em boi. Já as sequências parciais do gene CSN3 abrangeram parte dos íntrons 2 e 3 e o íntron 4 completo, além dos éxons 3, 4 e 5. Estas sequências apresentaram conservação acima de 94% com as correspondentes em boi. As análises de identificação de sequências repetitivas mostraram que 43,83% e 44,98% das sequências de DNA do clone A/2 e L/8, respectivamente, são representadas por elementos retrotransposons. Nas análises comparativas, tanto o gene CSN1S1 quanto o gene CSN3 parcial apresentaram sequências repetitivas búfalo específicas. A sequência ...
Among milk proteins, the caseins (alpha-s1, alpha-s2, beta- and kappa-casein) play a crucial role considering their high nutritional value and physicochemical characteristics which contribute to the manufacture of dairy products. These proteins are encoded by the CSN1S1, CSN1S2, CSN2 and CSN3 genes, respectively. In order to analyze the buffalo casein genes and compare the sequences with other species, the goal of the present study was to identify, characterize and sequence clones from a buffalo genomic library. A total of 33,792 clones were evaluated, and two clones were identified as positive, one for the CSN1S1 gene (clone A/2) and other for the CSN3 gene (clone L/8). The DNA sequence from clone A/2 identified the whole CSN1S1 and a partial sequence from the CSN2 genes. The DNA sequence from clone L/8 revealed a partial sequence from the CSN3 gene. The CSN1S1 gene presented a total of 17,008 bp organized in 19 exons ranging from 24 bp to 380 bp and 18 introns ranging from 90 bp to 1,710 bp. Comparative analysis showed sequence conservation higher than 85% on exons and introns of the CSN1S1 gene when compared with the cattle gene sequence. The partial sequence from the CSN2 gene included exon 9 and part of intron 8, with conservation higher than 98% when compared with the cattle sequence. The partial sequences of the CSN3 gene included parts of the introns 2 and 3, the whole sequence of intron 4 and exons 3, 4 and 5. These sequences showed conservation higher than 94% with cattle. The identification of repetitive sequences showed that 43.83% of DNA sequence from clone A/2 and 44,98% from clone L/8 were represented by retrotransposable elements. Further comparative analysis showed buffalo specific repetitive sequences in the CSN1S1 gene and the partial CSN3 gene with when compared with other bovids species. The coding sequence of the buffalo CSN1S1 gene showed 98%, 93%, and 90% of identity with the correspondent sequences in cattle ...
Silva, Fernando Evaristo da. "Efeito da adição de caseinato de sódio sobre a viabilidade do sêmen bubalino criopreservado." Botucatu, 2019. http://hdl.handle.net/11449/190848.
Full textResumo: O uso do sêmen refrigerado proporciona maiores taxas de prenhez se comparado ao do sêmen congelado. Essa diferença parece estar relacionada às lesões mais severas das membranas espermáticas desencadeadas pelo processo de congelação. Por sua habilidade de se ligar às proteínas ligadoras de espermatozoides e ao íon cálcio, o caseinato de sódio vem sendo estudado como uma substância capaz de inibir a capacitação espermática precoce, uma importante causa de diminuição da taxa de prenhez quando do uso de sêmen congelado. O primeiro objetivo deste estudo foi avaliar a possibilidade de um diluente comercial a base de gema de ovo, destinado à congelação de sêmen bovino, ser empregado para a criopreservação de sêmen bubalino; o segundo objetivo foi investigar o efeito do uso desse diluente, suplementado com caseinato de sódio, na criopreservação de espermatozoides bubalinos, por meio da avaliação dos espermatozoides, por citometria de fluxo, e da cinética espermática, empregando-se o sistema CASA. Na primeira parte do estudo, quando comparados os resultados das avaliações da cinética espermática e integridade das membranas plasmática e acrossomal, observou-se que o processo de congelação seminal promoveu mais danos celulares que o processo de refrigeração. Na segunda parte do estudo, não foram observados efeitos da adição do caseinato de sódio ao diluente a base de gema de ovo. A partir dos resultados do presente estudo foi possível concluir que o diluente a base de gema de ovo testad... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: The use of cooled semen results in higher pregnancy rates compared than the use of frozen semen. This result seems to be related to the more severe damages triggered by the freezing process, when compared to those observed during the refrigeration. Due to its ability to bind to sperm-binding proteins and calcium ions, sodium caseinate has been studied as a ubstance capable to prevent early sperm capacitation, a major cause of decreased pregnancy rate after using frozen semen. The first objective of this study was to evaluate if a commercial egg yolk diluent developed for freezing bovine semen could be used for buffalo semen cryopreservation; the second objective was to investigate the effect of this diluent, added with sodium caseinate, during the procedures of buffalo sperm cryopreservation, using flow cytometry and computer-assisted sperm analysis. In the first part of the study, comparing the results of spermatic kinetics and plasma and acrosomal membranes integrity, it was observed that the freezing process resulted in more cell damage than the cooling process. In the second part of the study, no effects of the addition of sodium caseinate to the egg yolk diluent were observed. From the results of the present study it was possible to conclude that the egg yolk-based diluent was suitable for buffalo semen cryopreservation and that the addition of sodium caseinate did not decrease the deleterious effects related to seminal cryopreservation.
Mestre
Seymour, William Matthew. "Responses to abomasal infusion of casein, hydrolyzed casein or methionine-lysine and dietary protein degradability in lactating cows." Diss., Virginia Polytechnic Institute and State University, 1987. http://hdl.handle.net/10919/49892.
Full textPh. D.
incomplete_metadata
Gingras, Denis. "René Cassin et les droits de l'homme." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq25238.pdf.
Full textGallagher, Jacqueline. "Hydrolysis of casein by food grade enzymes." Thesis, Cardiff University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320181.
Full textKannanayakal, Theresa Joseph. "Casein kinase 1 isoforms in degenerative disorders." Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1094264800.
Full textDocument formatted into pages; contains 150 p. Includes bibliographical references. Abstract available online via OhioLINK's ETD Center; full text release delayed at author's request until 2005 Sept. 7.
George, Sisilamma. "Physical mapping of the murine casein locus." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/13892.
Full textRios, Karina Ribeiro. "Efeito da remoção da fonte de zinco da mistura salina da dieta sobre o ganho de peso de ratos wistar e o valor nutritivo da caseina : influencia de adições crescentes de acido fitico." [s.n.], 2003. http://repositorio.unicamp.br/jspui/handle/REPOSIP/256230.
Full textDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia de Alimentos
Made available in DSpace on 2018-08-03T16:25:47Z (GMT). No. of bitstreams: 1 Rios_KarinaRibeiro_M.pdf: 519085 bytes, checksum: 22eba3b1a8c6784f7067751a10db8f1c (MD5) Previous issue date: 2003
Resumo: O zinco é um mineral que desempenha inúmeras funções biológicas, como catalisador para a atividade de mais de 300 enzimas, constituinte estrutural de muitas proteínas e como regulador na prevenção da formação de radicais livres. Dado a esta multiplicidade funcional, a deficiência de zinco é especialmente crítica em estádios de rápido crescimento e desenvolvimento onde seu requerimento é aumentado, na ingestão alimentar deficiente ou quando ocorre baixa biodisponibilidade do zinco. Com a descoberta da deficiência do mineral em humanos na década de 60 devido ao elevado consumo de ácido fítico por populações do Oriente Médio, os estudiosos acreditavam ser este um fato isolado, até que na década de 90 foi reconhecido como um problema de carência nutricional de ocorrência freqüente em países desenvolvidos. Com vistas a determinar a influência da fonte de zinco da mistura mineral da dieta AIN-93G e de adições de ácido fítico no crescimento e estado nutricional de zinco em ratos Wistar, estudou-se o efeito da suplementação com carbonato de zinco (56 % Zn) e ácido fítico na forma de hexafosfato de mioinositol (IP6), utilizando-se adições crescentes na dieta de caseína. Os resultados mostraram que apesar de o carbonato de zinco (56 % Zn) ter sido removido por 32 dias, não foi observada diferença estatística (p>0,05) para os índices de crescimento (consumo de dieta e ganho de peso) e valor nutritivo da caseína, determinado pelo Quociente de Eficiência da Caseína (PER). A concentração sérica de zinco não diferiu entre os animais do grupo Controle (dieta AIN-93G, 12,2 % de caseína) e os animais do grupo com dieta basal, sem a fonte de zinco da mistura mineral (ZnC03, 56% Zn), sendo a zincemia assegurada pelos 4,2 mg Zn I kg de caseína. Adições crescentes de ZnC03, 56% Zn, até 129,2 mg de zinco I kg de dieta basal durante 8 dias, após a remoção do mineral por 32 dias, resultaram em valores maiores para ganho de peso, porém até o limite de 86,7 mg Zn I kg dieta, correspondendo a um valor máximo de 98,6 gramas de ganho pondera!. A eficiência alimentar apresentou valores maiores a partir de 33,1 mg Zn I kg dieta e a concentração de zinco no soro dos animais, valores maiores para as adições de 65,4 e 129,2 mg Zn/kg dieta. Adições crescentes de ácido fítico à dieta basal, sem o ZnC03, 56 % Zn, da mistura mineral, num período de 32 dias, ocasionaram redução constante nos índices de crescimento (consumo de dieta e ganho de peso), no valor nutritivo da caseína determinado pelo Quociente de Eficiência Líquida da Caseína (NPR) e Quociente de Eficiência da Caseína (PER), no valor nutritivo dietético, determinado pelo Quociente de Conversão Alimentar (QCA) e na concentração sérica de zinco dos ratos. Os valores das digestibilidades (Aparente e Corrigida pela Dieta Aprotéica) não foram comprometidos pelas adições crescentes de fitato. Pelo exposto, pôde ser inferido que o baixo teor de zinco da dieta basal (1,1 mg Zn I kg dieta) praticamente não afetou o crescimento dos ratos, enquanto a influência de adições crescente de ácido fítico teve um efeito de notável redução dos índices determinados, com exceção da digestibilidade da caseína, num período experimental de 32 dias
Abstract: Zinc is a mineral with a variety of biological functions such as catalyzing the activity of more than 300 enzymes, being a structural constituent of many proteins and as a regulator in the prevention of free radical formation. Due to this functional multiplicity, a deficiency of zinc becomes especially critical during rapid growth and development stages where the requirement is even greater, in cases of deficient feeding or in cases of low zinc bioavailability. In the sixties, when deficiency of this mineral was first discovered in humans, due to the high ingestion of phytic acid by Middle Eastern populations, researchers believed this to be an isolated case. However, in the nineties it was recognized as a malnutritional problem, occurring mainly in large countries. With the objective of determining the influence of the zinc source in the mineral mixture of the AIN-93G diet, and of additions of phytic acid on the growth and nutritional state of zinc in Wistar rats, the effect of supplementation with zinc carbonate (56% Zn) was studied, and also the addition of phytic acid in the form of myoinositol hexaphosphate (IP6), adding increasing amounts to the casein diet. The results show that despite the zinc carbonate (56% Zn) having been removed from the diet for 32 days, no significant (p>0.05) difference was observed with respect to the growth indexes (diet consumption and weight gain) or nutritive value of the casein, as determined from the Protein Efficiency Ratio (PER). There was no difference in serum zinc concentration between that of the Control group of animals (AIN-93G diet, 12.2% casein) and that of the animals on the basal diet, without the source of zinc in the mineral mixture (ZnCO3, 56% Zn), zincemia being guaranteed by the 4.2 mg Zn I kg casein. Increasing additions of ZnCO3, 56% Zn, up to 129.2 mg zinc I kg basal diet for 8 days, after removing the mineral for 32 days, resulted in an increased weight gain, although only up to a limit of 86.7 mg Zn I kg diet, corresponding to a maximum pondered weight gain of 98.6 grams. Higher values for food efficiency were shown as from 33.1 mg Zn I kg diet, and higher values for the concentration of zinc in the animal serum were shown with additions of from 65.4 to 129.2 mg Zn I kg diet. Increasing additions of phytic acid to the basal diet containing no ZnCO3, 56% Zn in the mineral mixture, for a period of 32 days, led to constant reductions in the growth indexes (diet consumption and weight gain), in the nutritive value of the casein as determined by the net protein ratio (NPR) and protein efficiency ratio (PER), in the dietary nutrition value as determined by the food conversion ratio (FCR) and in the serum zinc concentration of the rats. The values for digestibility (apparent and corrected according to the aproteic diet) were unaffected by the increasing additions of phytate. From the results, it can be inferred that the low level of zinc in the basal diet (1.1 mg Zn I kg diet) showed practically no influence on the growth of the rats, whereas in an experimental period of 32 days, there was a notable effect in the reduction of the indexes determined, with the exception of that of casein digestibility, with increasing additions of phytic acid
Mestrado
Mestre em Alimentos e Nutrição
Molina, Urtubia Paula. "Casino Rancagua." Tesis, Universidad de Chile, 2006. http://repositorio.uchile.cl/handle/2250/100854.
Full textRychlík, Adam. "Casino Galaxy." Master's thesis, Vysoké učení technické v Brně. Fakulta stavební, 2017. http://www.nusl.cz/ntk/nusl-265370.
Full textEikås, Inger Kamilla. "Influence of Casing Shoe Depth on Sustained Casing Pressure." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for petroleumsteknologi og anvendt geofysikk, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-18650.
Full textKoch, Juliane. "Untersuchungen zur Hydrolyse von beta-Casein in Modellsystemen und in ausgewählten Käsesorten." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2004. http://nbn-resolving.de/urn:nbn:de:swb:14-1104851833062-82870.
Full textTomlinson, Anthony M. "Long range analysis of the mammalian casein locus." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/14550.
Full textParente, Aragão Ticiana. "CASSIA VIRGÍNICA® (Cassia occidentalis L.): abordagem farmacológica e toxicológica." Universidade Federal de Pernambuco, 2008. https://repositorio.ufpe.br/handle/123456789/3235.
Full textCassia occidentalis L., conhecida popularmente como Fedegoso, é amplamente utilizada como medicamento natural em regiões de florestas e outras áreas tropicais ao redor do mundo, para o tratamento de cólicas intestinais e uterinas, estados febris, processos inflamatórios e como diurético, laxante, expectorante e abortivo. O fitoterápico CASSIA VIRGÍNICA®, comercializado pelo Laboratório Pernambucano (LAPERLI), preparado a partir de caules e folhas de Cassia occidentalis, tem sido indicado para o tratamento de gripes, febres, úlceras varicosas e erisipelas. O presente trabalho teve como objetivo avaliar a presença de efeitos antiinflamatório, analgésico, antipirético e antiulcerogênico, bem como o potencial toxicológico reprodutivo do fitoterápico CASSIA VIRGÍNICA®. Foram usados ratos Wistar e camundongos, de ambos os sexos, adultos, tratados oralmente com o extrato seco de CASSIA VIRGÍNICA® em diferentes doses, 50, 100, 200, 250, 400 e 500mg/kg, na dependência do ensaio realizado. O estudo farmacológico foi realizado utilizando o modelo de edema de pata induzido por injeção subplantar de carragenina, dextrana e histamina, para avaliar a atividade antiinflamatória aguda; o modelo de analgesia utilizando o ácido acético para indução de contorções abdominais; o modelo de febre induzida por levedura de cerveja e o modelo de úlcera induzida pela administração de etanol. Para avaliar a toxicidade reprodutiva, ratas Wistar prenhes foram tratadas oralmente, durante os períodos de pré-implantação (1º ao 6º dia de gestação) e organogênese (7º ao 14º dia de gestação), nas doses de 250mg/kg e 500mg/kg. No 20º dia de gestação, as ratas foram sacrificadas, laparotomizadas e avaliadas quanto a parâmetros reprodutivos (número de fetos vivos e mortos, relação feto/mãe, massa dos fetos, das placentas e dos ovários, número de corpos lúteos, relação corpo lúteo/mãe, número de sítios de implantação, índice de implantação, número de sítios de reabsorção, perda pré e pósimplantação). Os resultados obtidos mostraram que o extrato seco de CASSIA VIRGÍNICA® produziu uma redução máxima aproximada de 55% e 41% no edema de pata induzido pela carragenina e dextrana, respectivamente, porém não, no edema induzido pela histamina. Houve diminuição significativa das contorções abdominais nos animais tratados com o fitoterápico de 71, 60 e 62%, respectivamente nas doses de 100, 200 e 400mg/kg. Com relação à atividade antipirética, o fitoterápico na dose de 400mg/kg produziu redução significativa da temperatura, maior do que 1°C (36,58±0,19 para 35,32±0,48), a partir da primeira hora de administração, de maneira semelhante à produzida pela dipirona (35,23±0,23). O extrato protegeu a mucosa gástrica contra lesões induzidas por etanol nas doses de 100 e 200mg/kg com percentual de área ulcerada igual a 8,52±1,34% e 11,62±1,24% correspondendo a uma redução em relação ao controle (19,73±2,41), de 56 e 41% da área ulcerada. Os resultados mostraram que não ocorreram diferenças estatisticamente significantes quanto aos parâmetros reprodutivos avaliados. Porém, foi constatada a presença de feto morto, tanto na dose de 250 quanto de 500mg/kg do extrato seco de CASSIA VIRGÍNICA®. Os resultados indicam que o fitoterápico possui atividades antiedematogênica, analgésica e antipirética, porém, mais estudos são necessários para esclarecer os mecanismos envolvidos nestas atividades. A vantagem do fitoterápico em relação aos antiinflamatórios atuais é que esta não apresenta propriedade irritante de mucosa gástrica, pelo contrário, possui um efeito gastroprotetor. A constatação de feto morto sugere que os estudos devem ser ampliados para melhor caracterizar os efeitos tóxicos do fitoterápico e seu uso não deve ser recomendado durante o período de gestação
Khandka, Rupak Kumar. "Leakage behind casing." Thesis, Norwegian University of Science and Technology, Department of Petroleum Engineering and Applied Geophysics, 2007. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-1633.
Full textAchieving zonal isolation by cementing annulus space between casing and well bore is an important job in many oil wells. Gas leakage in the annulus has been recognised as a major completion problem in the oil well. A successful cement job results in complete zonal isolation on a permanent basis. To achieve these goals, various factors such as well security, casing centralization, effective mud removal, and gas migration must be considered in the design. The design of the cement must be such that it prevents micro-annuli formation, stress cracking, corrosive fluid invasion, fluid migration, and annular gas pressure. However, permanent solutions to gas leakage has not emerged and gas leaks during and after the cement is set.
In this thesis work attempt has been made to deal the fluid leakage behind casing in two levels, firstly, revealed gas migration mechanism and, secondly, analytical modeling of cement sheath failure by internal and rising temperature. Several theories have been proposed regarding gas migration. In chaper 2 some probable physio-mechanical phenomena responsible for fluid migration in the cemented casing have been described. During cement setting and hardening gas migration is attributed to ineffective hydrostatic head, fluid loss during cementing, and the differential pressure occurrence due to the gelation. Micro annulus is attributed to the cement inability to form a good bond with the casing. Cyclic pressure and temperature variations during production also lead to the debonding or tensile failure or stress crushing of the cement causing gas migration. Gas leakage may occur years after production has ceased and well has been plugged and abandoned (P&A). Explanatory mechanism includes channeling, poor mud removal, shrinkage, and high cement permeability.
In chapter 3 efforts have been made to describe the case studies regarding zonal isolation. Case 1 describes the specialized cement design and placement procedures to mitigate casing vent flows (type: improve plan to avoid problem). Case 2 depicts a new cementing approach to improve and provide long term zonal isolation. Case 3 is related to the development of a methodology to evaluate the gas migration in cement slurries (type: predicting problem before it arises).
The stress in the cement is strongly connected with temperature and pressure, as well as lithology and in-situ stress. In chapter 4 an attempt has been made to quantify the cement failure as a function of down hole conditions and geometry and to define optimum mechanical properties to sustain the induced stresses. Analytical modeling has been done on the basis of plane strain in thin wall condition. Expressions for total stresses (hoop stress in casing, hoop stress in cement, and far field stress) are used to analyzed the cement integrity based on the case study well parameters of the Kristin Oil Field of Norway, Well R-3H (chapter 5). As this oil field is HTHP type, conventional cement is found not withstanding the stresses. In most of the situation tensile failure is the mode of failure, in some cases stress crushing and debonding. Improving the elasticity of cement or it’s flexural and tensile strength appeared to be an elegant solution to prevent cement failure (debonding, radial craking, and stress crushing). In addition, improvement can be made using high grade casing pipe (high Young’s modulus, low Poisson’s ratio). In reality a thick wall high grade (Q-125, SM-125) casing program has been selected in the Kristin Oil Field. The results of this study show the relevant dependency of stress principles with differential well temperature, pressure and field stress, Young’s modulus, thickness, and diameter of casing and cement sheath are also important.
Collins, Matthew C. J. "Casing effusion cooling." Thesis, University of Oxford, 2014. https://ora.ox.ac.uk/objects/uuid:8a7204f5-9436-4c11-b6d6-25aef0bff8f7.
Full textChakina, Marina. "Trolley for casino." Thesis, Blekinge Tekniska Högskola, Institutionen för maskinteknik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-11798.
Full textTezcucano, Molino Aline C. "Effects of enzymatic dephosphorylation on properties of bovine casein." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=102736.
Full textBovine whole casein, alpha-casein and beta-casein were dephosphorylated with potato acid phosphatase; optimum dephosphorylation conditions were 37°C, pH 5.8 for 6 h. The extents of dephosphorylation accounted for 71.6, 89.2 and 73.7% for whole casein, alpha-casein and beta-casein, respectively. The apparent Vmax and apparent K m for dephosphorylation of whole casein were 0.283 mumol P/mg casein min and 9.951 mg casein/l, respectively. SDS-alphaPAGE, urea-PAGE, RP-HPLC and ESI-MS demonstrated effects of dephosphorylation on the caseins. Urea-PAGE and ESI-MS confirmed the identities of the individual fractions. ESI-MS established (a) the molecular weight for alpha-casein and beta-casein as 23, 612 and 24, 017 Da, respectively; (b) random removal of 1, 2, 4, 6, 7 and 8 phosphate groups from alpha-casein and 1, 2, 3, 4 and 5 phosphate groups from beta-casein and (c) effects of incubation conditions. The effects of dephosphorylation of alpha-casein and beta-casein on the action of pepsin and trypsin were evaluated. Peptide mapping by RP-HPLC indicated that both proteases generated a complex mixture of peptides, with dephosphorylated peptides showing an increase in retention time. LC-ESI-MS and MS/MS in conjunction with the use of advanced bioinformatics software resulted in the identification of the peptides generated. Dephosphorylated alpha-casein and beta-casein showed the presence of peptides in which phosphate groups were removed, and were not observed in peptides from the corresponding native protein. Several of the peptides identified contained sequences that have been reported to be biologically active. Residual allergenicity of dephosphorylated whole casein, alpha-casein and beta-casein as well as peptic and tryptic products of these caseins was determined by an ELISA technique. The results demonstrated that removal of phosphate groups from whole casein, alpha-casein and beta-casein reduced allergenicity by 33, 31.2 and 24.4%, respectively. Proteolysis and dephosphorylation resulted in a significantly (p < 0.05) higher reduction in the antigen-antibody binding capacity compared to non-hydrolyzed and non-dephosphorylated caseins, particularly in the highly allergenic alpha-casein.
Büeler, Thomas. "Casein-Polymorphismus und gerinnungsrelevante Eigenschaften von Milch Schweizerischer Ziegenrassen /." [S.l.] : [s.n.], 2002. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=14876.
Full textMorris, Andrew Richard. "Characterisation of casein kinase 1 enzymes from Leishmania mexicana." Thesis, Keele University, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.510728.
Full textMorris, Gordon Alistair. "Hydrodynamic investigation of polysaccharides and their interactions with casein." Thesis, University of Nottingham, 2001. http://eprints.nottingham.ac.uk/13877/.
Full textWhyman, R. H. "Electrophoretic and stability studies of casein coated colloidal particles." Thesis, University of Leeds, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379647.
Full textAbbasi, Soleiman. "High pressure induced gelation of micellar casein + polysaccharide mixtures." Thesis, University of Leeds, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275631.
Full textAgnew, E. C. "The effects of casein on healing and plaque formation." Thesis, [Hong Kong] : University of Hong Kong, 1986. http://sunzi.lib.hku.hk/hkuto/record.jsp?B1232629X.
Full textScheepers, Robyn Clair. "Genetic variation of Kappa-casein in South African goats." Diss., University of Pretoria, 2009. http://hdl.handle.net/2263/28891.
Full textDissertation (MSc(Agric))--University of Pretoria, 2009.
Animal and Wildlife Sciences
unrestricted
Quinkenstein, Stephan. "Lymphoproliferation und Antigenspezifität von Lymphozyten frisch manifestierter Typ-I-Diabetiker gegen die Proteine bovines Serum-Albumin und [beta]-Casein [Beta-Casein] sowie Insulin." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969257120.
Full textLight, Christopher D. "Caspian Sea energy oil, politics and development in the Caspian Sea region." Thesis, Monterey, California. Naval Postgraduate School, 2004. http://hdl.handle.net/10945/1205.
Full textDinc, Havva. "Genotyping Of Beta-casein, Kappa-casein And Beta-lactoglobulin Genes In Turkish Native Cattle Breeds And Efforts To Delineate Bcm-7 On Human Pbmc." Phd thesis, METU, 2009. http://etd.lib.metu.edu.tr/upload/3/12611173/index.pdf.
Full textHansson, Malin. "Cherry Casino : - en kommunikationsgranskning." Thesis, Uppsala University, Department of Information Science, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6770.
Full textAbstract
Purpose/Aim: The purpose of this paper was to identify the communication process at the company Cherry casino and see what opinions the employees had about it. Moreover, an evaluation of the used strategies was done and an analysis about what perhaps could be done to improve the attitude, communication and in the end the result for the company.
Material/Method: The empirical material was gathered through qualitative interviews and theory application.
Main results: The transmission of information regarding the regular work related information works just fine and the channels used are well chosen. But more large-scale information that deals with the company’s plans, strategies and targets is not handled in the right way. Neither is the respond. Many express a lack of dialogue. Therefore my main conclusions is to develop a more friendly touch within the company, create a dialogue and let people at the bottom of the hierarchy know what is happening. The best way to do this is through the Intranet and the increase of positive feedback.
Keywords: Organizational communication, internal communication, casino, communication audit
TALEB, EINOLLAHI NASTARAN. "Design project : Caspian Land." Thesis, KTH, Urbana och regionala studier, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-233805.
Full textVong, Tze-ngai, and 黃子毅. "Casino boom in Macau: exploring casino liberalization's impact on Macau residents' sense of place and theirsatisfaction and support for casino development." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B49858798.
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Geography
Doctoral
Doctor of Philosophy
Ayers, Carolyn. "Effect of k-casein glycosylation on the properties of milk." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=26234.
Full textMatia-Meringo, Lara. "Interactions in acid casein gels and emulsion gels containing sugar." Thesis, University of Leeds, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396942.
Full textTsioulpas, Alexandros. "Role of minerals on casein micelle stability of bovine milk." Thesis, University of Reading, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429228.
Full textFang, Zih-Hua. "The genetic background of bovine αs1- and αs2-casein phosphorylation." Thesis, Paris, Institut agronomique, vétérinaire et forestier de France, 2017. http://www.theses.fr/2017IAVF0020.
Full textPhosphorylation of caseins (CN) is a crucial post-translational modification allowing caseins to aggregate as micelles. The formation and stability of casein micelles are important for transporting abundant minerals to the neonate and manufacturing of dairy products. Therefore, it is of great interest to explore variation in degrees of phosphorylation of caseins and study to what extent genetic and other factors contribute to this variation. This thesis aimed to investigate the genetic background of bovine milk protein composition with a focus on phosphorylation of αs1- and αs2-CN. Thus, two studies were conducted to quantify phosphorylation levels of αs1- and αs2-CN: one in French Montbéliarde (FM) using liquid chromatography coupled with electrospray ionization mass spectrometry and the other in Dutch Holstein Friesian (DHF) using capillary zone electrophoresis. In FM, in addition to the known isoforms αs1-CN-8P and-9P and αs2-CN-10P to -13P, three new phosphorylation isoforms were detected, namely αs2-CN-9P, αs2-CN-14P, and αs2-CN-15P. Relative concentrations of the phosphorylation isoforms varied considerably among cows. Phenotypic correlations showed that isoforms phosphorylated at higher degrees (αs1-CN-9P and αs2-CN-12P to -14P) correlated negatively with isoforms phosphorylated at lower degrees (αs1-CN-8P, αs2-CN-10P, and -11P). Furthermore, it was shown that αs1- and αs2-CN phosphorylation profiles changed across parity and lactation, and exploitable genetic variation for the phosphorylation degrees of αs1- and αs2-CN (defined as the proportion of higher-degree isoforms in αs1- and αs2-CN, respectively) exists in FM. In DHF, three αs2-CN isoforms, namely αs2-CN-10P to -12P, and the phosphorylation degrees of αs1- and αs2-CN were quantified. High intra-herd heritabilities were estimated for individual αs2-CN phosphorylation isoforms and the phosphorylation degrees of αs1- and αs2-CN (ranging from 0.54 to 0.89). This suggests that genetic factors contribute substantially to observed differences in αs1- and αs2-CN phosphorylation profiles. The correlation between the phosphorylation degrees of αs1- and αs2-CN was 0.94. Additionally, a total of 10 regions, distributed across Bos taurus autosomes (BTA) 1, 2, 6, 9, 11, 14, 15, 18, 24 and 28, were detected to be associated with individual αs1- and αs2-CN phosphorylation isoforms and their phosphorylation degrees in DHF. Regions on BTA1, 6, 11 and 14 were associated with multiple traits studied. Two quantitative trait loci (QTL) regions were detected on BTA1: one affecting αs2-CN production, and the other affecting αs1-CN PD and αs2-CN PD. The QTL region on BTA6 affected only individual αs2-CN isoforms. The QTL region on BTA11 and 14 affected relative concentrations of αs2-CN-10P and αs2-CN-11P, αs1-CN PD and αs2-CN PD. Results suggested that effects of identified genomic regions on αs1-CN PD and αs2-CN PD are probably due to changes in milk synthesis and phosphorus secretion in milk. Finally, differences among studies due to factors such as analytical methods, trait definitions, and breed on genetic parameters and correlations are discussed using the two dataset from this thesis. It is concluded that differences in heritability estimates for αs1-CN-8P and -9P, αs2-CN-10P, -11P and -12P, and αs1-CN PD between FM and DHF were mainly due to genetic differences between breeds. As for αs2-CN PD, it was defined differently in FM and DHF due to analytical methods used. It is shown that both trait definitions successfully quantified the proportion of isoforms with higher degrees of phosphorylation because of similar estimated correlations using both definitions on the FM dataset. Additionally, it is hypothesized that a two-casein-kinase system is involved in the phosphorylation of αs1- and αs2-CN based on results in this thesis
Du, Hongwen. "Microstructural Changes in Casein Micelles during Acidification of Skim Milk." DigitalCommons@USU, 1994. https://digitalcommons.usu.edu/etd/5408.
Full textBecerril, Diez Azucena. "Influence of chelating agents on proteolysis of micellar casein slurries." DigitalCommons@CalPoly, 2016. https://digitalcommons.calpoly.edu/theses/1635.
Full textChevalier, Elodie. "Développement et caractérisation de matériaux antimicrobiens extrudés à base de caséines : mise au point d'étiquettes bio-résistantes pour l'optimisation de la traçabilité en fromagerie." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSES042/document.
Full textDevelopment of innovative biodegradable, edible and functionalized material comes from a triple socio-economic expectation in the field of sustainable development (decrease in synthetic non-biodegradable polymers), of natural solutions for food preservation (trend of “clean label” by food protection through active and smart packaging to avoid over-use of food additives) and of food safety (microbiological safety and traceability). Development in that field, started few decades ago is slowed down by production process (wet process), which is not an easy scale up process. However, a few years ago industrial process technique as extrusion started developing. In the present work, the twin-screw extrusion process was successfully applied to produce polymer based on protein raw material: acid casein, rennet casein and sodium caseinate. Extracted from caw milk, these three caseins own different characteristics, which affect material properties (mechanical, water sensitive properties). Matrix functionalization through organic acid addition bring an interesting antimicrobial response against Escherichia coli. Blending hydrophobic molecules as waxes (beeswax, candelilla wax and carnauba wax) creates a complex composite material which increases the range of available properties as improved water vapor barrier allowed by beeswax addition. Water sensitive properties are key points to consider at each step of material development and to understand relationships between the different ingredients (protein, plasticizer, waxes, antimicrobial agents). This manuscript shows the feasibility in the development of casein based material as biodegradable, edible and antimicrobial material, to apply and use in the food packaging industry or other industries
Qian, Xi. "Regulation of β-Casein Gene Expression by Octamer Transcription Factors and Utilization of β-Casein Gene Promoter to Produce Recombinant Human Proinsulin in the Transgenic Milk." ScholarWorks @ UVM, 2014. http://scholarworks.uvm.edu/graddis/316.
Full textGonçalves, Barbosa da Silva Mirtes. "Avaliação toxicológica pré-clínica do extrato seco de Cassia occidentalis L. (CASSIA VIRGÍNICA®)." Universidade Federal de Pernambuco, 2009. https://repositorio.ufpe.br/handle/123456789/3269.
Full textCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
Cassia occidentalis L. (Leguminosae) popularmente conhecida como fedegoso é geralmente encontrada em regiões de florestas e em outras áreas tropicais ao redor do mundo. Na medicina tradicional, raízes, folhas e caules são usados como laxante, antiinflamatório, analgésico, antipirético, diurético, hepatoprotetor, vermicida e abortivo. Baseado principalmente no largo uso popular, a Cassia occidentalis é comercializada por alguns laboratórios farmacêuticos entre eles o Laboratório Pernambucano Ltda. (LAPERLI) com o nome comercial de CASSIA VIRGÍNICA®. O fitoterápico CASSIA VIRGÍNICA®, preparado a partir de caules e folhas de Cassia occidentalis (CO), tem sido indicado para o tratamento de gripes, febres, úlceras varicosas e erisipelas. Apesar do amplo uso desta espécie, poucos são os trabalhos disponíveis na literatura sobre seu potencial toxicológico. A maioria dos estudos toxicológicos utilizando Cassia occidentalis, refere-se à toxicidade de suas sementes. Neste sentido, o objetivo deste trabalho foi avaliar a segurança da administração oral do extrato seco de caules e folhas de Cassia occidentalis (CASSIA VIRGÍNICA®) em ratos Wistar de ambos os sexos. Para isto, foram realizados testes de toxicidade aguda nas doses de 0.625 a 5.0 g/kg, de toxicidade subcrônica e de toxicidade reprodutiva nas doses de 0.10, 0.50 e 2.5 g/kg/dia. Os resultados demonstraram que, nos estudos de toxicidade aguda, CO não produziu morte ou sinais de toxicidade em doses de até 5.0 g/kg. A administração por 30 dias de CO não alterou os parâmetros bioquímicos e hematológicos dos animais tratados, que se mantiveram dentro dos valores de referência para espécie. Entretanto, foi constatada uma discreta diarréia durante o período de tratamento. Não foram observadas alterações significativas na massa corporal nem no consumo de água e ração. Também não foram registradas alterações significativas nas massas, absoluta e relativa, e nem na morfologia macroscópica externa ou microscópica dos principais órgãos. Nos estudos que avaliaram a capacidade reprodutiva em machos, o tratamento durante 60 dias com CO não produziu efeitos tóxicos sobre os parâmetros reprodutivos ou sobre os conceptos. Além disso, não houve alteração significativa nas massas dos órgãos reprodutivos (epidídimo, vesícula seminal, ducto deferente, testículos, próstata) nem no número de espermatozóides. Desta forma, conclui-se que extrato seco de caules e folhas de Cassia occidentalis (CASSIA VIRGÍNICA®) é seguro por via oral, uma vez que apresentou baixa toxicidade aguda e subcrônica e não interferiu na capacidade reprodutiva dos ratos Wistar
Böhm, Anke. "Untersuchungen zur Proteolyse von para-k-Casein: vom Modell zum Käse." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2003. http://nbn-resolving.de/urn:nbn:de:swb:14-1055498240843-26828.
Full textK-casein is one of the original casein components in milk. Model-experiments under cheese ripening conditions demonstrate the hydrolysis of para-k-Casein, which is the hydrophobic part of kappa-casein, by rennet and rennet substitutes fromase and suparen. Different water contents influences the dimension of hydrolysis of para-k-Casein. A water content of 60 % usual found in cheese results in a great number of hydrolysis products from para-k-Casein with molecular weights between 400-1400 Da. The hydrolyses was investigated for a time period of 15 weeks by several analytical methods (i.e RP-HPLC, ESI-MS, electrophoretic methods, and others). Investigations by electrophoresis of the ripening process of acid curd cheese demonstrated that para-k-Casein is also hydrolysed in this type of cheese, but the detection is quite difficult