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Relevant bibliographies by topics / Castor oil-induced gastric enteropooling

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Academic literature on the topic 'Castor oil-induced gastric enteropooling'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Castor oil-induced gastric enteropooling"

1

Ezeigbo, I.I, C.E.C.C. Ejike, M.I. Ezeja, and O. Eneh. "ANTIOXIDANT AND ANTIDIARRHOEAL ACTIVITY OF Manniophyton africanum LEAF EXTRACT IN MICE." Continental J. Animal and Veterinary Research 2 (June 16, 2010): 41–47. https://doi.org/10.5281/zenodo.818031.

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The antidiarrhoeic activity of the methanolic leaf extract of <em>Manniophyton africanum </em>(MEMA) has been evaluated out in mice using different models (Castor oil-induced diarrhoea, effects on gastrointestinal motility, and castor oil-induced gastric enteropooling). MEMA (200,400 and 600 mg/kg, p.o.) inhibited at 5% significance level, the frequency of defecation and reduced the wetness of faecal droppings in castor oil-induced diarrhoea, markedly inhibited the movement of charcoal meal plug through the gastrointestinal tract, in a dose dependent manner, comparable to diphenoxylate and atr

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2

Madubuike, K. G., M. I. Ezeja, and I. I. Ezeigbo. "ANTIDIARRHOEAL ACTIVITY OF Pterocarpus santalinoides LEAF EXTRACT IN MICE." Continental J. Animal and Veterinary Research 4, no. 1 (2012): 1–6. https://doi.org/10.5281/zenodo.818249.

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The antidiarrhoeal activity of the methanolic leaf extract of <em>Pterocarpus</em> <em>santalinoides</em> was evaluated in mice using different experimental models: castor oil – induced diarrhoea, gastrointestinal motility test and castor oil – induced enteropooling. The extract (200,400 and 800 mg/kg, p.o.) significantly (p < 0.05) reduced the number of wet faeces in the castor oil – induced diarrhoea, as well as inhibited the movement of charcoal meal plug through the gastrointestinal tract. Both actions were dose – dependent and comparable to those of Loperamide, used as the positive con

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3

Konate, Kiessoun, Meda Nag Tiero Roland, Diao Mamounata, et al. "ANTIMICROBIAL PROFILES, ANTIDIARRHEAL AND ANTIPYRETIC CAPACITIES OF PHENOL ACID RICH-FRACTIONS FROM XIMENIA AMERICA L., (OLACACEAE) IN WISTAR ALBINO RATS." International Journal of Pharmacy and Pharmaceutical Sciences 10, no. 10 (2018): 62. http://dx.doi.org/10.22159/ijpps.2018v10i10.25485.

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Objective: The present study aim to evaluate antimicrobial and antidiarrheal activities of phenol acid-rich fractions of roots from Ximenia americana L., in animal models in order to confirm the ethnomedicinal use of Ximenia Americana L., roots.Methods: In vitro antibacterial (Minimum inhibitory concentration (MIC), Minimum bactericidal concentration (MBC) and time-kill studies) of phenol-rich fractions of roots from Ximenia americana L., was assessed using eight bacteria strains (Gram-negative). The anti-diarrheal activity was evaluated using castor using castor oil induced diarrhea whereas A

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4

Ismail, H. A., H. S. Hassan, M. Ilyas, A. A. Sadam, and A. A. Sadam. "Evaluation of Phytochemical and Anti-diarrheal Activity of Methanol Stembark Extract of Combretum hypopilinum Diels (Combretaceae)." Nigerian Journal of Pharmaceutical Research 17, no. 1 (2021): 45–52. http://dx.doi.org/10.4314/njpr.v17i1.5.

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Introduction: The plant Combretum hypopilinum has many medicinal uses in Africa. Infusion of fresh or dry leaves are commonly taken as cholagogic, diuretic, and purgative and also to treat gastrointestinal disorders, including diarrhoea, dysentery, and stomach achesObjective: To carry out phytochemical and antidiarrheal studies on the methanol stembark extract of C. hypopilinum.Methods: The C. hypopilinum stembark (1kg) were extracted with methanol using cold maceration method for 9 days. The solvent was removed by rotary evaporator and the extract was partitioned with n-hexane, chloroform and

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5

Ansari, Sameen Fatima, Arif-ullah Khan, Neelum Gul Qazi, Fawad Ali Shah, and Komal Naeem. "Proteomic Analysis and In Vivo Studies Reveal the Potential Gastroprotective Effects of CHCl3 and Aqueous Extracts of Ficus palmata." Evidence-Based Complementary and Alternative Medicine 2021 (May 30, 2021): 1–11. http://dx.doi.org/10.1155/2021/6613140.

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Ficus palmata is rich in several phytochemicals such as chromone, isoflavones, terpenes, lignans, coumarins, glycosides, and furanocoumarins and have been traditionally used for the management of different gastrointestinal disorders. This research reveals the effects of Ficus palmata fruit extracts—Ficus palmata chloroform (Fp.CHCl3) and Ficus palmata aqueous (Fp.Aq)—on gut activity through in vivo and in vitro analyses. Antidiarrheal and enteropooling assays were analyzed with castor oil-induced diarrhea and intestinal fluid accumulation. Jejunum tissues of rabbits were isolated (antispasmodi

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6

Shah, Rushabh S., Jeet Ravat, Misbah A. Momin, and Alka P. Mukne. "Antidiarrheal activity of aqueous extract of leaves of Euphorbia hirta L." Journal of Pharmacy & Pharmacognosy Research 9, no. 5 (2021): 716–29. http://dx.doi.org/10.56499/jppres21.1054_9.5.716.

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Context: Euphorbia hirta L. is widely distributed in the Indian subcontinent and has many ethnomedicinal uses. Traditionally, the leaves of E. hirta have been used as antidiarrheal agents, for bronchial and respiratory diseases and against conjunctivitis. Aims: To evaluate the antidiarrheal activity of the aqueous extract of leaves of Euphorbia hirta. Methods: Steam and aqueous extracts of leaves of E. hirta were evaluated for their antidiarrheal activity by in vitro antiprotozoal and antimicrobial activity testing, in vivo evaluation of % protection against diarrhea in castor-oil induced rat

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7

A., Nwabunike I., Okoli C. O., Ezeugwu P., et al. "ANTIDIARRHEAL POTENTIALS OF SCHWENCKIA AMERICANA L. (SOLANACEAE): A COMPARATIVE STUDY OF THE AERIAL PART AND ROOT EXTRACTS." International Journal of Pharmacy and Pharmaceutical Sciences 10, no. 1 (2018): 195. http://dx.doi.org/10.22159/ijpps.2018v10i1.21928.

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Objective: Schwenckia americana L. (Solanaceae) is employed as a decoction of either the leaves, roots or the whole plant in the treatment of diarrhoea in most West African countries. Using a comparative study approach, the antidiarrheal potentials of its aerial part and root extracts were evaluated to substantiate its local use in diarrhoea management.Methods: In vivo effects of the extracts on rodent models of diarrhea, enteropooling and gastric motility induced by castor oil were investigated as well as their effects on acetylcholine and histamine-induced guinea pig ileal contractions in vi

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8

Joseph Olanrewaju Oyindamola, Godwin Christian Akuodor, Malachy Ifeanyi Obi, Evelyn Ogochukwu Nwachukwu, Kingsley Chimsorom Chilaka, and Omo Eric Irinmwinuwa. "Comparative assessment of the anti-diarrhoeal effects of the ethanol leaf and stem extracts of lantana camara in Wistar rats." Magna Scientia Advanced Research and Reviews 3, no. 1 (2021): 035–45. http://dx.doi.org/10.30574/msarr.2021.3.1.0059.

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The antidiarrhoeal effects of Lantana camara ethanol leaf and stem extracts were compared in Wistar rats. The phytochemical and acute toxicity tests were also determined. The extracts were evaluated for castor oil- induced diarrhoea and enteropooling as well as intestinal transit in rats. The ethanol stem extract produced significant (P < 0.05), while the ethanol leaf extract produced significant (P < 0.01) dose dependent protection on rats against castor oil induced diarrhoea. The stem extract inhibited intestinal transit time and caused significant (P < 0.05), while leaf extract cau

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9

Kamadyaapa, Davie Rexon, Mavuto Masopera Gondwe, Mathulo Shauli, Constance Sewani Rusike, and Jehu Iputo. "EVALUATION OF ANTIDIARRHEAL ACTIVITY OF ETHANOLIC LEAF EXTRACT OF ERIOBOTRYA JAPONICA LINDL." Asian Journal of Pharmaceutical and Clinical Research 11, no. 9 (2018): 502. http://dx.doi.org/10.22159/ajpcr.2018.v11i9.27256.

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Objective: The study was carried out to investigate the antidiarrheal activity of ethanolic leaf extract of Eriobotrya japonica (EEJ) using various models of experimental diarrhea.Methods: Antidiarrheal property of EEJ at 100, 200, and 400 mg/kg/bwt was evaluated using castor oil-induced diarrhea, castor oil-induced enteropooling, and gastrointestinal propulsive models of experimental diarrhea in Sprague Dawley rats of both sexes, weighing 200–250 g. Cytotoxicity test of EEJ was performed using brine shrimp bioassay.Results: Toxicity assay of EEJ showed a lethal concentration value of 1225 μg/

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10

Akuodor, Godwin Christian, Grace Akanimo Essiet, John Azubuike Ekenjoku, et al. "Antidiarrhoael and antimicrobial effects of ethanol root bark extract from Salacia lehmbachii." Journal of Herbmed Pharmacology 10, no. 2 (2021): 188–93. http://dx.doi.org/10.34172/jhp.2021.20.

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Introduction: The roots of Salacia lehmbachii are used in Nigerian folklore medicine without scientific basis. The present study was aimed to investigate the antidiarrheal and antimicrobial activities of the ethanol extract of S. lehmbachii root bark. Methods: The antidiarrheal activity was examined using castor oil induced diarrhoea method. The ethanol root bark extract effects on intestinal transit time and enteropooling were also evaluated in rats, while antimicrobial activity was conducted on selected microorganisms. The acute toxicity test and phytochemical screening of the extract were a

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