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1

Furushima, Daisuke, Takuma Nishimura, Norikata Takuma, et al. "Prevention of Acute Upper Respiratory Infections by Consumption of Catechins in Healthcare Workers: A Randomized, Placebo-Controlled Trial." Nutrients 12, no. 1 (2019): 4. http://dx.doi.org/10.3390/nu12010004.

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Catechins, phytochemicals contained mainly in green tea, exhibit antiviral activity against various acute infectious diseases experimentally. Clinical evidence supporting these effects, however, is not conclusive. We performed a placebo-controlled, single-blind, randomized control trial to evaluate the clinical effectiveness of consumption of catechins-containing beverage for preventing acute upper respiratory tract infections (URTIs). Two hundred and seventy healthcare workers were randomly allocated to high-catechin (three daily doses of 57 mg catechins and 100 mg xanthan gum), low-catechin
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2

Ozato, Naoki, Tohru Yamaguchi, Tatsuya Kusaura, et al. "Effect of Catechins on Upper Respiratory Tract Infections in Winter: A Randomized, Placebo-Controlled, Double-Blinded Trial." Nutrients 14, no. 9 (2022): 1856. http://dx.doi.org/10.3390/nu14091856.

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Tea catechins are plant-derived compounds that improve immune functions. Previous randomized control trials have demonstrated the efficacy of primarily epi-type catechins against upper respiratory tract infections (URTIs). Green tea can be consumed in several ways, including popular bottled beverages. These beverages, however, require sterilization during manufacturing, which results in catechin isomerization. We conducted a randomized, double-blinded, placebo-controlled trial involving healthy Japanese participants to evaluate whether catechin consumption via bottled beverages has an alleviat
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3

Bashir, Khawaja Muhammad Imran, Hye-Ryeon An, Bertoka Fajar Surya Perwira Negara, et al. "Toxicity Assessment of Catechins on Representative Aquatic Organisms and Terrestrial Plant." Toxins 17, no. 5 (2025): 244. https://doi.org/10.3390/toxins17050244.

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Catechins, renowned for their health benefits, have unexamined environmental impacts. This study assessed the toxicity of crude catechin and catechin hydrate on invertebrate larvae, plant, and microalgae. The survival rates of Daphnia magna Straus and Artemia salina L. were monitored every 24 h over a three-day period. The germination rate and radicle length of Lactuca sativa L. was measured every 24 h for four days. Inhibitory effects were evaluated in both freshwater and seawater cultures of Chlorella vulgaris Beijerinck, with cell density recorded every 24 h and yield inhibition calculated
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4

Nandika, Dodi, Khaswar Syamsu, Arinana, Dina Tiara Kusumawardhani, and Yuni Fitriana. "Bioactivities of catechin from gambir (Uncaria gambir Roxb.) against wood-decaying fungi." BioResources 14, no. 3 (2019): 5646–56. http://dx.doi.org/10.15376/biores.14.3.5646-5656.

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Gambir is one of the most economically important natural products of Indonesia. Indonesia accounts for 80% of the global exports of this product. The product contains catechin, a phenolic compound of the flavonoid group, which has demonstrated bioactivity against horticulture-destroying fungi. However, its bioactivity in controlling wood-decaying fungi has not yet been reported. A laboratory study was conducted to examine the characteristics of the catechin of gambir and its bioactivity against the wood-decaying fungi Schizophylum commune Fr. Extraction of catechin from gambir was conducted vi
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5

Sasaki, Geoffrey Y., Yael Vodovotz, Zhongtang Yu, and Richard S. Bruno. "Catechin Bioavailability Following Consumption of a Green Tea Extract Confection Is Reduced in Obese Persons without Affecting Gut Microbial-Derived Valerolactones." Antioxidants 11, no. 12 (2022): 2490. http://dx.doi.org/10.3390/antiox11122490.

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Obesity-related cardiometabolic disorders are driven by inflammation, oxidative stress, and gut dysbiosis. Green tea catechins protect against cardiometabolic disorders by anti-inflammatory, antioxidant, and prebiotic activities. However, whether obesity alters catechin bioavailability remains unknown. We hypothesized that obesity would decrease catechin bioavailability due to altered gut microbiota composition. Obese and healthy persons completed a pharmacokinetics trial in which a confection formulated with green tea extract (GTE; 58% epigallocatechin gallate, 17% epigallocatechin, 8% epicat
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Osterc, G., M. Štefančič, A. Solar, and F. Štampar. "Potential involvement of flavonoids in the rooting response of chestnut hybrid (Castanea crenata × Castanea sativa) clones." Australian Journal of Experimental Agriculture 47, no. 1 (2007): 96. http://dx.doi.org/10.1071/ea05149.

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The involvement of different quercetins [quercetin-3-O-rhamnoside (quercitrin), quercetin-3-D-galactoside (hyperoside) and rutin] and catechins (catechin, catechol) in the rooting process of leafy cuttings was studied in two hybrid chestnut (Castanea crenata × Castanea sativa) clones, Maraval and Marsol. Both clones differed strongly in rooting results. The Maraval clone cuttings, which had a high rooting rate, contained, on average, higher amounts of all quercetins in different plant parts (leaves and basal cuttings) than the Marsol clone, which had a low rooting rate. There was a highly sign
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7

Ha, Lai Thi Ngoc, Tran Thi Hoai, Hoang Lan Phuong, and Nguyen Van Lam. "Exploitation of Catechin Extract from Pruned Tea Leaves as a Promising Food Preservative Against Lipid Oxidation." Vietnam Journal of Agricultural Sciences 7, no. 1 (2024): 2040–51. http://dx.doi.org/10.31817/vjas.2024.7.1.03.

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In Vietnam, a tea-producing country, the tea buds and top three leaves are normally used for tea production while older leaves are pruned and discarded as agricultural waste in the winter. The present study aimed to exploit catechins from pruned tea leaves and use them as natural antioxidants for applications in the food industry. Catechins were analyzed using the guideline of ISO 14502-2-2005 by HPLC-MWD. The contents of catechins in pruned tea leaves of ten popular tea varieties were relatively high, ranging from 65.57 to 136.88 mg/g dry weight. The optimized conditions for catechin extracti
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8

Liu, Chao-Tzu, and Jason T. C. Tzen. "Exploring The Relative Astringency of Tea Catechins and Distinct Astringent Sensation of Catechins and Flavonol Glycosides via an In Vitro Assay Composed of Artificial Oil Bodies." Molecules 27, no. 17 (2022): 5679. http://dx.doi.org/10.3390/molecules27175679.

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Artificial oil bodies covered by a recombinant surface protein, caleosin fused with histatin 3 (a major human salivary peptide), were employed to explore the relative astringency of eight tea catechins. The results showed that gallate-type catechins were more astringent than non-gallate-type catechins, with an astringency order of epicatechin gallate > epigallocatechin gallate > gallocatechin gallate > catechin gallate > epigallocatechin > epicatechin > gallocatechin > catechin. As expected, the extension of brewing time led to an increase in catechin content in the tea in
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Kukushkina, Татьяна Абдулхаиловна, Vera Andreevna Kostikova, and Elena Petrovna Khramova. "CONTENT OF CATECHINS IN LEAVES AND ROOTS OF COMARUM SALESOVIANUM AND COMARUM PALUSTRE (ROSACEAE)." chemistry of plant raw material, no. 2 (May 22, 2024): First. http://dx.doi.org/10.14258/jcprm.20240212561.

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The search for additional sources of catechins among the local flora is relevant today. The method for determining the content of catechins by the spectrophotometric method in the leaves of the subshrub Zalesov's cinquefoil (Comarum salesovianum (Steph.) Asch. et Graebn.) from the Rosaceae Juss. family was validated. The content of catechins in terms of (±)-catechin in the leaves and rhizomes of two species of the genus Comarum ‒ C. salesovianum and C. palustre L. (marsh cinquefoil) was studied. The highest content of catechins was found in the roots of C. palustre (4%) and leaves of C. saleso
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Mita, Soraya Ratnawulan, Marline Abdassah, Unang Supratman, et al. "Nanoparticulate System for the Transdermal Delivery of Catechin as an Antihypercholesterol: In Vitro and In Vivo Evaluations." Pharmaceuticals 15, no. 9 (2022): 1142. http://dx.doi.org/10.3390/ph15091142.

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Gambir (Uncaria Gambir, Roxb.) contains catechins that is often empirically used to treat various diseases. Catechins can reduce cholesterol levels by inhibiting coenzyme HMG-CoA reductase that plays a role in cholesterol metabolism. Research has been carried out covering the optimization of transethosomal catechins, the formulation of Transethosomal Catechin Gel (TCG) and Non-Transethosomal Catechin Gel (NTCG), which were then tested for catechin permeation from these gel preparations in vitro using Franz’s diffusion cell with PTFE membranes. The anti-hypercholesterol activity test was carrie
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Hye, M. A., M. A. Taher, M. Y. Ali, M. U. Ali, and Shahed Zaman. "Isolation of (+)-Catechin from Acacia Catechu (Cutch Tree) by a Convenient Method." Journal of Scientific Research 1, no. 2 (2009): 300–305. http://dx.doi.org/10.3329/jsr.v1i2.1635.

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Biologically important polyphenol (+)-catechin was isolated from catechu, the extract of the red heartwood of Acacia Catechu tree (Khoiyer tree). The isolation procedure was developed to get better yield (25%) and to reduce the isolation cost and time. The structure of the isolated (+)-catechin was confirmed with several spectral analyses and chemical studies. Keywords: Acacia Catechu; (+)-catechin; Polyphenol. © 2009 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. DOI: 10.3329/jsr.v1i2.1635
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12

Furushima, Daisuke, Yu Otake, Natsumi Koike, et al. "Investigation of the Oral Retention of Tea Catechins in Humans: An Exploratory Interventional Study." Nutrients 13, no. 9 (2021): 3024. http://dx.doi.org/10.3390/nu13093024.

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Green tea catechin ingestion or gargling exhibit anti-viral activity against upper respiratory infection. We hypothesized that retention in the oral cavity could improve the anti-viral effects of catechins. The present study investigated the oral retention of catechins in humans and the effect of catechin beverage viscosity on oral retention. Two intervention studies with different test beverages, beverage-C (40 mL, containing 73.4 mg of catechins) and beverage-XT (40 mL, beverage-C containing 100 mg xanthan gum) were conducted in 20 healthy volunteers (mean age 38.7 years). Catechin concentra
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13

Nafisah, Umi, Aptika Oktaviana Trisna Dewi, and Anes Aisna Hana Lulu. "Determination of Catechin Content in Green and Black Tea (Camellia sinensis L.) by UV-Vis Spectrophotometric Method." Jurnal Sains dan Kesehatan 6, no. 1 (2024): 24–30. http://dx.doi.org/10.25026/jsk.v6i1.2166.

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Tea is one of the most commonly consumed beverages around the world. The chemical compounds contained in tea have a good effect on health because they contain polyphenolic compounds, catechins. This study examined the catechin compound content of black tea and green tea from Karanganyar (A) and Malang (B). This research aims to determine the differences in catechin levels in black and green tea types in Malang, East Java, and Karanganyar, Central Java plantations. The research method used was experimental. Identification of catechin content was done using UV-Vis Spectrophotometry method. Tea i
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14

Sasaki, Geoffrey, Yael Vodovotz, Zhongtang Yu, and Richard Bruno. "Catechin Bioavailability Is Reduced in Obese Persons Without Altering Gut Microbial-Derived Valerolactones Following Consumption of a Green Tea Extract Confection." Current Developments in Nutrition 4, Supplement_2 (2020): 468. http://dx.doi.org/10.1093/cdn/nzaa045_101.

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Abstract Objectives Green tea extract (GTE) protects against obesity in rodents by reducing gut permeability that otherwise provokes endotoxemia-mediated inflammation. However, whether obesity affects catechin bioavailability and microbial metabolism is unknown. We hypothesized that obesity will reduce catechin bioavailability by increasing microbial biotransformation of catechins. Methods Obese persons (n = 10 M/7F; 33.5 ± 0.7 kg/m2) and age-matched healthy persons (n = 10 M/9F; 21.7 ± 0.4 kg/m2) completed a pharmacokinetics (PK) trial in which a GTE confection [290 mg epigallocatechin gallat
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15

Syukri, Daimon. "Optimization of Cathechin Extraction for Development of Liquid Hand Soap Made From Gambier." Andalasian International Journal of Agriculture and Natural Sciences (AIJANS) 4, no. 01 (2023): 31–36. http://dx.doi.org/10.25077/aijans.v4.i01.31-36.2023.

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This study has aimed to determine the potential use of catechins derived from gambier as an anti-microbial raw material in the manufacture of hand washing liquid soap. The study started from the purification process of catechins from gambier and continued with the addition of gambier to the soap formula looking for hand washing. In this study, there were some difficulties in obtaining catechin extracts that could dissolve in water due to the character of catechins that did not dissolve completely in water. Therefore, the optimization of the catechin extraction process is optimized first. The c
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Kumar, G. Sravan, Ilahi Shaik, Hepzibah Rani Singh, et al. "Catechin as Natural Product Antifouling Agent against Biofilm Forming Bacteria from Visakhapatnam Coast, Andhra Pradesh, India." UTTAR PRADESH JOURNAL OF ZOOLOGY 44, no. 23 (2023): 1–10. http://dx.doi.org/10.56557/upjoz/2023/v44i233755.

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The aim of this work was to evaluate the effectiveness of Catechin as natural product antifoulants (NPAs) by inhibiting bacterial growth. 10 different medicinal plants namely Pongamia pinnata, Mucuna pruriens, Garcinia cambogia, Acacia catechu, Curcuma longa, Curcuma xanthorrhiza, Coffea arabica, Griffonia simplicifolia, Bacopa monnieri and Piper nigrum extracts were evaluated for potential natural product antifouling agent. Of which Acacia catechu and Curcuma longa showed best results, a significant zone of inhibition of bacteria was achieved by aqueous catechin. The secondary metabolite cate
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Wang, Yiru, Yujing Suo, Huawei Li, et al. "Diversity of Catechin Content in the Leaves of Persimmon Germplasms." Horticulturae 9, no. 4 (2023): 464. http://dx.doi.org/10.3390/horticulturae9040464.

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Catechins are essential phenolic compounds in persimmon. However, the catechin content in the leaves of persimmon germplasms has not been systematically and comprehensively evaluated. To systematically assess catechin variation in different growth stages and astringency types of persimmon leaves, the young and adult leaves catechin content of 249 persimmon germplasms from Korea, Japan, and 16 provinces in China was quantified using an HPLC method. The results showed that the content of (−)-epicatechin (EC) and (−)-gallocatechin gallate (GCG) had higher coefficient of variation (CV) values in p
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Mohd Zin, Zamzahaila, Nursyafiqah Mohamad, Chong Kah Hui, Nurul Izwanie Majid, and Mohd Khairi Zainol. "Effect of Acidified Ethanol on Antioxidant Properties of Morinda citrifolia Leaf Extract and Its Catechin Derivatives." Current Research in Nutrition and Food Science Journal 9, no. 1 (2021): 172–83. http://dx.doi.org/10.12944/crnfsj.9.1.17.

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This study was conducted to investigate the effect of ethanol acidification on the antioxidant properties of Morinda citrifolia leaf (MCL) extract and its catechin derivatives. Four different ethanol (100%, 99.5%, 70%, 50%) with or without 0.5% acetic acid were used for extraction. The antioxidant profile was studied with DPPH radical scavenging activity, FRAP and TPC. The quantification of catechins in MCL was performed using HPLC, and the identification of catechins derivatives was performed with Ultra UPLC-TWIMS-QTOF. The results showed that an extraction solvent composed of 70% ethanol: 29
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Naparlo, Katarzyna, Grzegorz Bartosz, Ireneusz Stefaniuk, Bogumil Cieniek, Miroslaw Soszynski, and Izabela Sadowska-Bartosz. "Interaction of Catechins with Human Erythrocytes." Molecules 25, no. 6 (2020): 1456. http://dx.doi.org/10.3390/molecules25061456.

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The aim of this study was to characterize the interaction of chosen catechins ((+)-catechin, (−)-epigallocatechin (EGC), and (−)-epigallocatechin gallate (EGCG)) with human erythrocytes and their protective effects against oxidative damage of erythrocytes. Uptake of the catechins by erythrocytes was studied by fluorimetry, their interaction with erythrocyte membrane was probed by changes in erythrocyte osmotic fragility and in membrane fluidity evaluated with spin labels, while protection against oxidative damage was assessed by protection against hemolysis induced by permanganate and protecti
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Sun, Haiyan, Meichen Yin, Danqing Hao, and Yixiao Shen. "Anti-Cancer Activity of Catechin against A549 Lung Carcinoma Cells by Induction of Cyclin Kinase Inhibitor p21 and Suppression of Cyclin E1 and P–AKT." Applied Sciences 10, no. 6 (2020): 2065. http://dx.doi.org/10.3390/app10062065.

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Catechin is one of the major polyphenols in teas, beans, and berry fruits. A number of studies have confirmed that catechins extract possesses health benefits in the prevention of various chronic diseases. In this study, the anti-cancer activity and mechanism of catechin against non-small cell lung cancer A549 cells were investigated. The inhibitory rate of catechin on the proliferation of A549 cells reached 19.76% at a concentration of 600 μmol·L−1 with 24 h incubation. The results demonstrated that catechin inhibits A549 cells by increasing the expressions of p21 and p27 in the cancer cells.
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Mabe, Katsuhiro, Masami Yamada, Itaro Oguni, and Tsuneo Takahashi. "In Vitro and In Vivo Activities of Tea Catechins against Helicobacter pylori." Antimicrobial Agents and Chemotherapy 43, no. 7 (1999): 1788–91. http://dx.doi.org/10.1128/aac.43.7.1788.

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ABSTRACT The catechin epigallocatechin gallate showed the strongest activity of the six tea catechins tested against Helicobacter pylori(MIC for 50% of the strains tested, 8 μg/ml). It had bactericidal activity at pH 7 but not at pH ≤5.0. In infected Mongolian gerbils,H. pylori was eradicated in 10 to 36% of the catechin-treated animals, with significant decreases in mucosal hemorrhage and erosion. Tea catechins, therefore, may have therapeutic effects on H. pylori infection.
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Ai, Zeyi, Shuyuan Liu, Fengfeng Qu, Haojie Zhang, Yuqiong Chen, and Dejiang Ni. "Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers." Molecules 24, no. 6 (2019): 1185. http://dx.doi.org/10.3390/molecules24061185.

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The transcellular transport and metabolism of eight green tea catechins (GTCs) were studied in Caco-2 monolayers, with the aim of investigating the effect of cis–trans isomerism on the membrane permeability and biotransformation of GTCs. The results showed that the catechin stereochemistry significantly affects the efflux transport rather than the absorption transport in the Caco-2 monolayers. The trans catechins showed a better transcellular permeability than their corresponding cis (epi) catechins in the efflux transport, as the efflux amount of trans catechins were all significantly higher
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Suprahman, Nisa Yulianti, Bulan Rosita Sari, Riri Fauziyya, and Fatimah. "Investigation of catechin’s anti-inflammatory activity: A bioinformatics and molecular docking study." Acta Biochimica Indonesiana 7, no. 2 (2024): 199. https://doi.org/10.32889/actabioina.199.

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Background: Inflammation plays a key role in the progression of many chronic diseases. As a country with rich biodiversity, Indonesia offers numerous phytochemicals with potential for drug development, including catechin, a natural compound with anti-inflammatory properties. Objective: This study aimed to identify potential anti-inflammatory targets of catechin and evaluate its inhibitory potency through molecular docking simulations. Methods: Data acquisition and refinement were conducted using the NCBI, STRING, and STITCH databases, with intersections identified through Venn diagrams. Molecu
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Kharisma, Viol Dhea, Muhammad Hermawan Widyananda, Arif Nur Muhammad Ansori, Aondohemba Samuel Nege, Sin War Naw, and Alexander Patera Nugraha. "Tea catechin as antiviral agent via apoptosis agonist and triple inhibitor mechanism against HIV-1 infection: A bioinformatics approach." Journal of Pharmacy & Pharmacognosy Research 9, no. 4 (2021): 435–45. http://dx.doi.org/10.56499/jppres21.1009_9.4.435.

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Context: Human immunodeficiency virus (HIV) antiretrovirals that target the binding of viral enzyme are chosen as the lead solution in the treatment of HIV-1 infection, such as non-catalytic site integrase inhibitor (NCINI), nevirapine, and darunavir. There are natural compounds from specific plants that can be effective in treating HIV-1 infection such as tea catechin. Tea catechin administration causes a decrease in viral load and inhibition of entry mechanisms and an increased effect of apoptosis in infected cells. Aims: To identify the triple inhibitor mechanism in tea catechins against th
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Zheng, Kaiwen, Kai Guo, Jing Xu, et al. "Study on the interaction between catechin and cholesterol by the density functional theory." Open Chemistry 18, no. 1 (2020): 357–68. http://dx.doi.org/10.1515/chem-2020-0038.

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AbstractCatechin – a natural polyphenol substance – has excellent antioxidant properties for the treatment of diseases, especially for cholesterol lowering. Catechin can reduce cholesterol content in micelles by forming insoluble precipitation with cholesterol, thereby reducing the absorption of cholesterol in the intestine. In this study, to better understand the molecular mechanism of catechin and cholesterol, we studied the interaction between typical catechins and cholesterol by the density functional theory. Results show that the adsorption energies between the four catechins and choleste
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Patel, Snehal, and Vinit Patel. "Inhibitory effects of catechin isolated from Acacia catechu on ovalbumin induced allergic asthma model." Nutrition & Food Science 49, no. 1 (2019): 18–31. http://dx.doi.org/10.1108/nfs-01-2018-0016.

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Purpose Polyphenols possess anti-allergic activities. Catechin is one of the polyphenols that are abundantly present in the Acacia catechu. In this study, the authors investigated the effect of catechin isolated from A. catechu in an experimental mouse model of ovalbumin (OVA)-induced allergic asthma. Design/methodology/approach Catechin was isolated from A. catechu, and phytochemical analysis was carried out by ultraviolet visible and thin-layer chromatography (TLC), high pressure thin-layer chromatography was used for the determination of an amount of catechin present. In a first set of an e
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Tarahovsky, Yu S., S. G. Gaidin, and Yu A. Kim. "Effects of Catechins on the Formation of Collagen Fibrils in vitro." Biofizika 69, no. 4 (2024): 707–14. http://dx.doi.org/10.31857/s0006302924040038.

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Some aspects of therapeutic action of catechins are associated with their effects on the deposition of collagen fibrils in tissues. It is assumed that this process is controlled through signaling and regulatory pathways in cells that catechins affect, however, the direct interactions of polyphenols with structural proteins cannot be excluded. The present work investigates the direct effect of (+)-catechin and epigallocatechin gallate on the formation of collagen fibrils in vitro. Turbidimetty, differential scanning calorimetry and transmission electron microscope data showed that (+)-catechin
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Mhya, Daniel Hassan, Abdulrashid Mohammed, and Theophilus Tagun Dawus. "Investigation of NADPH-Oxidase’s Binding Subunit(s) for Catechin Compounds Induce Inhibition." European Journal of Advanced Chemistry Research 4, no. 3 (2023): 10–18. http://dx.doi.org/10.24018/ejchem.2023.4.3.140.

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Catechins are natural polyphenolic compounds with ability to minimize excess free radicals through different mechanisms including inhibition of NADPH oxidase (NOX) activity. NOX is a complex enzyme made-up of several subunits, where molecules including catechins binds to exert their effect. Hence, the attempt to probe the NOX enzyme’s binding subunit of catechins-induce effect. Several in-silico techniques were deployed in probing the NOX enzyme’s binding subunit of the catechins. The catechins were downloaded from PubChem database in SDF files. The five NOX subunits with PDB ID: 3A1F, 1OV3, 1
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Gomes, Jessica Santos, Érica Abadia da Costa, Rodrigo Alejandro Abarza Munoz, Alberto de Oliveira, and Raquel Maria Ferreira Sousa. "Selective Electrochemical Detection of Catechin Compounds in Herbal Medicines." Journal of The Electrochemical Society 169, no. 1 (2022): 017516. http://dx.doi.org/10.1149/1945-7111/ac4bbf.

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Most electrochemical sensors reported for catechin determination in herbal medicines actually involve the detection of not only catechins but also other flavonoids. This work proposes a strategy to selectively detect and quantify flavan-3-ol, known as catechins, in the presence of other flavonoids by complexation with AlCl3. Flavonoids (e.g., rutin, quercetin) form stable complex with AlCl3 which affect the electrooxidation of these molecules. Hence, the electrochemical oxidation of catechin is free from the interference of other flavonoids as shown by differential-pulse voltammetry using glas
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Chairunisa, Ully, Hafiva Ulyanti, and Muthia Fadhila. "IN SILICO TEST AND CHARACTERIZATION TEST OF THE NANOEMULSION FORMULA OF CATECHIN COMPOUNDS AS ANTI ACNE." International Journal of Pharmaceutical Sciences and Medicine 9, no. 5 (2024): 23–29. http://dx.doi.org/10.47760/ijpsm.2024.v09i05.003.

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Catechin is a polyphenolic compound produced by green tea and gambier plants with catechin activity as an antibacterial. The method that can be used to predict the activity of catechin compounds as anti-acne is by using the in silico method and catechins are unstable because they are difficult to dissolve in water, making transdermal delivery inefficient. As a drug delivery system, nanoemulsions can increase the effectiveness of drug therapy by reducing the particle size to the nanometer range. The aim of this research is to find out how to test in silico protein (1VJY) with catechin compounds
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Ndacyayisenga, Joseph, Esther Maina, Lilian Ngeny, Fred Wamunyokoli, and Festus Tolo. "Purple tea catechins exhibit high antiproliferative activity and synergism with cisplatin against the triple-negative breast cancer cell line 4T1." Archives of Biological Sciences, no. 00 (2023): 39. http://dx.doi.org/10.2298/abs230816039n.

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The objectives of this study were the selection of the best tea clones with high catechin content among the known tea clones in Rwanda and Kenya, the examination of their antiproliferative effects on the triple-negative breast cancer (TNBC) cell line (4T1), and an evaluation of their combination index with cisplatin. The quantification of catechin contents in 14 different tea clones and 5 different processed teas was performed by high-performance liquid chromatography (HPLC). A comparative study of antiproliferative activities of catechin extracts from purple, TRFK306, and BB35 tea clones on t
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Krishnamoorthy, Rajapandiyan, Abdulraheem R. Adisa, Vaiyapuri Subbarayan Periasamy, Jegan Athinarayanan, Subash-Babu Pandurangan, and Ali A. Alshatwi. "Colonic Bacteria-Transformed Catechin Metabolite Response to Cytokine Production by Human Peripheral Blood Mononuclear Cells." Biomolecules 9, no. 12 (2019): 830. http://dx.doi.org/10.3390/biom9120830.

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Human gut microbes are a profitable tool for the modification of food compounds into biologically active metabolites. The biological properties of catechins have been extensively investigated. However, the bioavailability of catechin in human blood plasma is very low. This study aimed to determine the biotransformed catechin metabolites and their bioactive potentials for modulating the immune response of human peripheral blood mononuclear cells (PBMCs). Biotransformation of catechin was carried out using in-vitro gut microbial biotransformation method, the transformed metabolites were identifi
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33

M., Y. Ali, U. Ali M. та A. Hye M. "Studies on catechu : Isolation of (+)-catechin from different parts of Acαciα cαtechu". Journal of Indian Chemical Society Vol. 84, Dec 2007 (2007): 1258–60. https://doi.org/10.5281/zenodo.5826724.

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Green University of Bangladesh, Farmgate, Dhaka-1215, Bangladesh <em>E-mail</em>: aliyusuffm@yahoo.com Department of Chemistry, Rajshahi University, Rajshahi-6205, Bangladesh <em>Manuscript received 23 April 2007, revised 28 August 2007, accepted 6 September 2007</em> A convenient method for isolation of (+)-catechin from A. <em>catechu</em> Willd. has been suggested. (+)-Catechin content of different&nbsp;parts of the tree and effect of storage time on (+)-catechin content has also been reported.
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Yang, Meei-Ju, Shwu-Yuan Lee, Chieh-I. Liu, et al. "Catechin Photolysis Suppression by Aluminum Chloride under Alkaline Conditions and Assessment with Liquid Chromatography–Mass Spectrometry." Molecules 25, no. 24 (2020): 5985. http://dx.doi.org/10.3390/molecules25245985.

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Tea is rich in catechins and aluminum. In this study, the process of catechin photolysis was applied as a model for examining the effects of aluminum chloride (AlCl3) on the structural changes of catechin and the alteration of aluminum complexes under blue light irradiation (BLI) at pH 8 using liquid chromatography and mass spectrometry techniques. Additionally, the effects of anions on catechin upon the addition of AlCl3 and treatment with BLI were also studied. In this study, when 1 mM catechin was treated with BLI, a superoxide anion radical (O2•−) was generated in an air-saturated aqueous
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Yu, Kwang-Won. "Catechin-Polymer Production Using (+)-Catechin Substrate by Laccase." Journal of Biotechnology and Bioindustry 10 (December 2022): 44–52. http://dx.doi.org/10.37503/jbb.2022.10.44.

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Isemura, Mamoru. "Catechin in Human Health and Disease." Molecules 24, no. 3 (2019): 528. http://dx.doi.org/10.3390/molecules24030528.

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Jiang, Yongcheng, Zhenming Zhang, and Jiachun Zhang. "Quality Characteristics of Karst Plateau Tea (Niaowang) in Southwest China and Their Relationship with Trace Elements." Toxics 11, no. 6 (2023): 502. http://dx.doi.org/10.3390/toxics11060502.

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This study investigated the relationship between the characteristics of quality components and trace elements of Niaowang tea from Guizhou Province in mountainous plateau areas. The contents of catechin monomers and eight other trace elements were measured using high-performance liquid chromatography (HPLC) and inductively coupled plasma mass spectrometry (ICP-MS), respectively. The results showed that the tender summer leaves of Niaowang tea in Guizhou Province had the highest content of catechins at 3558.15~2226.52 μg·g−1. The content of ester catechins was the highest in summer, amounting t
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Wedy Nasrul. "PENYUSUNAN STANDAR OPERASIONAL PROSEDUR (SOP) PRODUKSI KATEKIN DAN TANIN DARI GAMBIR." Jurnal Pengabdian UntukMu NegeRI 8, no. 3 (2024): 313–18. http://dx.doi.org/10.37859/jpumri.v8i3.7757.

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Standard Operating Procedures (SOP) for production are documents that contain step-by-step instructions to guide workers on how to carry out repetitive production processes for a job to achieve production goals. Production SOP function to guide workers in the production process and maintain the quality of the products produced. The Sharia Producer Cooperative "Gambir Anam Koto Mandiri" which produces catechins and tannins does not yet have a production SOP. So it is important to prepare SOP for catechin production and gambier farming to help workers in the production process and maintain the q
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Coșarcă, Sanda, Corneliu Tanase, and Daniela Lucia Muntean. "Therapeutic Aspects of Catechin and Its Derivatives – An Update." Acta Biologica Marisiensis 2, no. 1 (2019): 21–29. http://dx.doi.org/10.2478/abmj-2019-0003.

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Abstract Catechin and its derivatives are polyphenolic benzopyran compounds. The condensation of catechin units leads to the formation of condensed tannins. It is found in appreciable amount in green tea leaves, cocoa, red wines, beer, chocolate, etc. It possesses important antioxidant, antibacterial, antifungal, antidiabetic, anti-inflammatory, antiproliferative and antitumor properties. The present review outlines recent updates and perspectives of the effects of catechins and the pharmacodynamic mechanisms involved.
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Syamsu Nur, Andi Nur Aisyah, Alfat Fadri, Sharfianty, Amriani Sapra, and Fitriyanti Jumaetri Sami. "Comparative study of catechin levels from green tea, oolong tea and black tea product with various treatments." GSC Biological and Pharmaceutical Sciences 14, no. 1 (2021): 001–10. http://dx.doi.org/10.30574/gscbps.2021.14.1.0416.

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Background: Tea is a refreshing drink that contains polyphenol compounds, namely catechins that are used for medicine and cosmetics. This study was to assess the content of catechin compounds in green tea, oolong and black tea products from Indonesia, China and Taiwan. Methods: Some tea products are brewed at varying temperatures (75±2; 85±2 and 95±20 C) and times (5; 10 and 15 minutes). Identification of catechin compounds was carried out using chemical reagents and UV spectrophotometry. The level of cathecin in tea products were analyzed by spectrophotometer at 280 nm wavelength. Results: Th
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Suhail, Mohd, Asma parveen, Amjad Husain та Mohd Rehan. "Exploring Inhibitory Mechanisms of Green Tea Catechins as Inhibitors of a Cancer Therapeutic Target, Nuclear Factor-κB (NF-κB)". Biosciences, Biotechnology Research Asia 16, № 04 (2019): 715–23. http://dx.doi.org/10.13005/bbra/2787.

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Nuclear factor kappa B (NF-κB), a transcription factor is a well-established cancer therapeutic target. NF-κB’s linkage with cancer is known through the constitutive activation of NF-κB in several cancer types. The most important role of NF-κB as a transcription factor is its ability to promote cell survival through the induction of transcription of target pro-survival genes and thus inhibition of programmed cell death (PCD) by resulting proteins in both malignant and normal cells. Current findings have unveiled that green tea catechins exert anticancer effect by inhibiting the activity of var
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Cibikkarthik,, T. "Protein targets in red complex pathogens for catechin." Bioinformation 17, no. 12 (2021): 1105–8. http://dx.doi.org/10.6026/973206300171105.

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The development of antimicrobial drug resistance has encouraged scientists to develop alternate methods to combat infectious pathogens associated with dental diseases. Therefore, it is of interest to predict interactions for catechin (a plant derived compound) with protein targets in the red complex pathogens using computer aided network tools. However, in vitro and in vivo studies are warranted to confirm the antimicrobial effect of catechin (gallocatechin, epicatechin, epigallactocatechin (EGC) and gallolyl catechins) on the dental pathogens.
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Takahashi, Masaki, Masashi Miyashita, Katsuhiko Suzuki, et al. "Acute ingestion of catechin-rich green tea improves postprandial glucose status and increases serum thioredoxin concentrations in postmenopausal women." British Journal of Nutrition 112, no. 9 (2014): 1542–50. http://dx.doi.org/10.1017/s0007114514002530.

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Elevated postprandial hyperglycaemia and oxidative stress increase the risks of type 2 diabetes and CVD. Green tea catechin possesses antidiabetic properties and antioxidant capacity. In the present study, we examined the acute and continuous effects of ingestion of catechin-rich green tea on postprandial hyperglycaemia and oxidative stress in healthy postmenopausal women. Participants were randomly assigned into the placebo (P,n11) or green tea (GT,n11) group. The GT group consumed a catechin-rich green tea (catechins 615 mg/350 ml) beverage per d for 4 weeks. The P group consumed a placebo (
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Unno, Keiko, Monira Pervin, Kyoko Taguchi, Tomokazu Konishi, and Yoriyuki Nakamura. "Green Tea Catechins Trigger Immediate-Early Genes in the Hippocampus and Prevent Cognitive Decline and Lifespan Shortening." Molecules 25, no. 7 (2020): 1484. http://dx.doi.org/10.3390/molecules25071484.

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Senescence-accelerated mouse prone 10 (SAMP10) mice, after ingesting green tea catechins (GT-catechin, 60 mg/kg), were found to have suppressed aging-related decline in brain function. The dose dependence of brain function on GT-catechin indicated that intake of 1 mg/kg or more suppressed cognitive decline and a shortened lifespan. Mice that ingested 1 mg/kg GT-catechin had the longest median survival, but the dose was less effective at suppressing cognitive decline. The optimal dose for improving memory acquisition was 60 mg/kg, and memory retention was higher in mice that ingested 30 mg/kg o
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Li, Qiqiong, Florence Van Herreweghen, Marjan De Mey, Geert Goeminne, and Tom Van de Wiele. "The Donor-Dependent and Colon-Region-Dependent Metabolism of (+)-Catechin by Colonic Microbiota in the Simulator of the Human Intestinal Microbial Ecosystem." Molecules 27, no. 1 (2021): 73. http://dx.doi.org/10.3390/molecules27010073.

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The intestinal absorption of dietary catechins is quite low, resulting in most of them being metabolized by gut microbiota in the colon. It has been hypothesized that microbiota-derived metabolites may be partly responsible for the association between catechin consumption and beneficial cardiometabolic effects. Given the profound differences in gut microbiota composition and microbial load between individuals and across different colon regions, this study examined how microbial (+)-catechin metabolite profiles differ between colon regions and individuals. Batch exploration of the interindividu
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Kasyanenko, N., V. Rolich, and D. Nikitin. "COMPLEXES OF IRON (III) WITH CATECHIN AND THEIR INTERACTION WITH DNA." Russian Journal of Biological Physics and Chemisrty 8, no. 3 (2024): 265–70. http://dx.doi.org/10.29039/rusjbpc.2023.0619.

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Modern anticancer drugs have increased toxicity to the human body. There are also cases when tumor cells show resistance to certain classes of drugs. Therefore, the search and study of new compounds with antitumor properties remains an urgent task. In recent years, interest has arisen in the antioxidant and antitumor activity of catechins, which belong to plant flavonoids, and therefore their use in therapy, as well as their combined use with more toxic compounds, can reduce the negative impact of treatment on the body as a whole. Typically, antitumor activity is determined by the ability of c
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Syukri, Daimon, Fauzan Azima, and Rivan Aprialdho. "STUDY ON THE UTILIZATION OF CATECHINS FROM GAMBIR (UNCARIA GAMBIR ROXB) LEAVES AS ANTIOXIDANTS COOKING OIL." Andalasian International Journal of Agriculture and Natural Sciences (AIJANS) 3, no. 01 (2022): 12–25. http://dx.doi.org/10.25077/aijans.v3.i01.12-25.2022.

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Catechins are flavonoid molecules that act as antioxidants in the body. The degradation of palm oil with catechin treatment (400, 200, 100, 50, 0) was investigated in this work (ppm). The goal of this study was to see how efficient catechins are as antioxidants in cooking oil and what the optimal treatment would be for the amount of catechins added. Catechin concentration, antioxidant IC50, free fatty acid, peroxide value, water content, color, and fatty acid profile are all analyzed using GC-MS. Treatment E (400 ppm) was found to be the most effective, with free fatty acid values of 0.45 perc
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Li, Hongxu, Qiaomei Wang, Houqiao Wang, et al. "LCLN-CA: A Survival Regression Analysis-Based Prediction Method for Catechin Content in Yunnan Sun-Dried Tea." Horticulturae 10, no. 12 (2024): 1321. https://doi.org/10.3390/horticulturae10121321.

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Catechins are pivotal determinants of tea quality, with soil environmental factors playing a crucial role in the synthesis and accumulation of these compounds. To investigate the impact of changes in tea garden soil environments on the catechin content in sun-dried tea, this study measured the catechin content in soil samples and corresponding tea leaves from Nanhua, Yunnan, China. By integrating the variations in catechin content with those of 17 soil factors and employing COX regression factor analysis, it was found that pH, organic matter (OM), fluoride, arsenic (As), and chromium (Cr) were
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Dubey, Nidhi, Nitin Dubey, Rajendra Mehta, and Ajay Saluja. "Estimation of Catechin in Ayurvedic Oil Formulations Containing Acacia catechu." Journal of AOAC INTERNATIONAL 92, no. 4 (2009): 1021–26. http://dx.doi.org/10.1093/jaoac/92.4.1021.

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Abstract A sensitive, simple, rapid, and efficient HPTLC method was developed and validated for the analysis of catechin in marketed Ayurvedic oil formulations containing Acacia catechu. Chromatography of methanolic0.1 formic acid (7:3, v/v) extracts of these formulations was performed on silica gel 60 F254 aluminum-backed TLC plates of 0.2 mm layer thickness. The plate was developed up to 85 mm with the ternarymobile phase chloroformacetone0.1 formic acid (7.7 + 1.5 + 0.8, v/v/v) at 22 2C with 20 min of chamber saturation. The system produced compact spots of catechin at an Rf value of 0.36.
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Kubicova, Lenka, Gert Bachmann, Wolfram Weckwerth, and Vladimir Chobot. "(±)-Catechin—A Mass-Spectrometry-Based Exploration Coordination Complex Formation with FeII and FeIII." Cells 11, no. 6 (2022): 958. http://dx.doi.org/10.3390/cells11060958.

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Catechin is an extensively investigated plant flavan-3-ol with a beneficial impact on human health that is often associated with antioxidant activities and iron coordination complex formation. The aim of this study was to explore these properties with FeII and FeIII using a combination of nanoelectrospray-mass spectrometry, differential pulse voltammetry, site-specific deoxyribose degradation assay, FeII autoxidation assay, and brine shrimp mortality assay. Catechin primarily favored coordination complex formation with Fe ions of the stoichiometry catechin:Fe in the ratio of 1:1 or 2:1. In the
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