Academic literature on the topic 'CATHETER ABLATION/methods'
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Journal articles on the topic "CATHETER ABLATION/methods"
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FONTAINE, G. "Cardiac Arrhythmias Treated by Catheter Ablation Methods." Annals of Internal Medicine 103, no. 5 (November 1, 1985): 803. http://dx.doi.org/10.7326/0003-4819-103-5-803_1.
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Calkins, Hugh, Andrea Natale, Tara Gomez, Alex Etlin, and Moe Bishara. "Comparing rates of atrioesophageal fistula with contact force-sensing and non-contact force-sensing catheters: analysis of post-market safety surveillance data." Journal of Interventional Cardiac Electrophysiology 59, no. 1 (November 22, 2019): 49–55. http://dx.doi.org/10.1007/s10840-019-00653-5.
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Abstract Purpose There is limited data on the specific incidence of serious adverse events, such as atrioesophageal fistula (AEF), associated with either contact force (CF) or non-CF ablation catheters. Since the actual number of procedures performed with each type of catheter is unknown, making direct comparisons is difficult. The purpose of this study was to assess the incidence of AEF associated with the use of CF and non-CF catheters. Additionally, we aimed to understand the workflow present in confirmed AEF cases voluntarily provided by physicians. Methods The number of AEFs for 2014–2017 associated with each type of catheter was extracted from an ablation device manufacturer’s complaint database. Proprietary device sales data, a proxy for the total number of procedures, were used as the denominator to calculate the incidence rates. Additional survey and workflow data were systematically reviewed. Results Both CF and non-CF ablation catheters have comparably low incidence of AEF (0.006 ± 0.003% and 0.005 ± 0.003%, respectively, p = 0.69). CF catheters are the catheter of choice for left atrium (LA) procedures which pose the greatest risk for AEF injury. Retrospective analysis of seven AEF cases demonstrated that high power and force and long RF duration were delivered on the posterior wall of the left atrium in all cases. Conclusions CF and non-CF ablation catheters were found to have similar AEF incidence, despite CF catheters being the catheter of choice for LA procedures. More investigation is needed to understand the range of parameters which may create risk for AEF.
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Haanschoten, Danielle M., Ahmet Adiyaman, Jaap Jan J. Smit, Peter Paul H. M. Delnoy, Anand R. Ramdat Misier, Fabiano Porta, Robert P. H. Storm van Leeuwen, and Arif Elvan. "Hybrid Ventricular Tachycardia Ablation after Failed Percutaneous Endocardial and Epicardial Ablation." Cardiology 145, no. 2 (November 8, 2019): 88–94. http://dx.doi.org/10.1159/000503251.
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Introduction: Recurrent ventricular tachycardia (VT) after percutaneous ablation is associated with a high morbidity and mortality. We assessed the feasibility of open chest extracorporeal circulation (ECC)-supported 3D multielectrode mapping and targeted VT substrate ablation in patients with previously failed percutaneous endocardial and epicardial VT ablations. Methods: In patients with previously failed percutaneous endocardial and epicardial VT ablations and a high risk of hemodynamic collapse during the procedure, open chest ECC-supported mapping and ablation were performed in a hybrid EP lab setting. Electro-anatomic maps (3D) were acquired during sinus rhythm and VT using a multielectrode mapping catheter (HD grid; Abbott or Pentaray, Biosense Webster). Irrigated radiofrequency ablations of all inducible VT were performed with a contact force ablation catheter. Results: Hybrid VT ablation was performed in 5 patients with structural heart disease (i.e., 3 with previous old myocardial infarction and 2 with nonischemic cardiomyopathy) and recurrent VT. Acute procedural success was achieved in all patients. Four patients were successfully weaned off the ECC. In 1 patient with a severely reduced LVEF (16%), damage to the venous graft occurred after sternotomy and that patient died after 1 month. Four patients (80%) remained VT free after a median follow-up of 6 (IQR 4–10) months. Conclusion: In high-risk patients with previously failed percutaneous endocardial and epicardial VT ablations, open chest ECC-supported multielectrode epicardial mapping revealed a VT substrate in all of the patients, and targeted epicardial ablation abolished VT substrate in these patients.
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Gupta, Dhiraj, Tom De Potter, Tim Disher, Kiefer Eaton, Laura Goldstein, Leena Patel, Daniel Grima, Maria Velleca, and Graça Costa. "Comparative effectiveness of catheter ablation devices in the treatment of atrial fibrillation: a network meta-analysis." Journal of Comparative Effectiveness Research 9, no. 2 (January 2020): 115–26. http://dx.doi.org/10.2217/cer-2019-0165.
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Atrial fibrillation (AF) ablation is most commonly performed using radiofrequency (RF) and cryoballoon (CB) catheters. Ablation Index is a novel lesion-quality marker associated with improved outcomes in RF ablation. Due to lack of direct comparative evidence between the latest generations of technologies, there is uncertainty regarding the best treatment option. Aim: To conduct a network meta-analysis to evaluate the comparative effectiveness of RF with Ablation Index to other catheter ablation devices in the treatment of AF. Methods: Searches for randomized and nonrandomized prospective comparative studies of ablation catheters were conducted in multiple databases. The outcome of interest was 12-month freedom from atrial arrhythmias after a single ablation procedure. Studies were grouped as high-, low- and unclear-quality based on study design and balanced baseline patient characteristics. Bayesian hierarchical network meta-analysis was conducted and results presented as relative risk ratios with 95% credible intervals (CrIs). Results: 12 studies evaluating five different catheter ablation devices were included. Radiofrequency ablation with Ablation Index was associated with statistically significantly greater probability of 12-month freedom from atrial arrhythmias than Arctic Front (relative risk: 1.77; 95% CrI: 1.21–2.87), Arctic Front Advance™ (1.41; 1.06–2.47), THERMOCOOL™ (1.34; 1.17–1.48) and THERMOCOOL SMARTTOUCH™ (1.09; 1–1.3). Results were robust in multiple sensitivity analyses. Conclusion: Radiofrequency catheter with Ablation Index is superior to currently available options for 12-month freedom from atrial arrhythmias after AF ablation. This study provides decision-makers with robust, pooled, comparative evidence of the latest ablation technologies.
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Meshkova, M., and A. Doronin. "Analysis of Complications in 1000 Consecutive Radiofrequency Catheter Ablations of Atrial Fibrillation." Ukrainian Journal of Cardiovascular Surgery, no. 2 (43) (June 18, 2021): 67–71. http://dx.doi.org/10.30702/ujcvs/21.4306/m009067-071/844-037-08.
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Introduction. In patients with drug-refractory symptomatic atrial fibrillation (AF), radiofrequency catheter ablation has become the main treatment option. Despite advances in technology and experience, the incidence of complications for this procedure reported by researchers still varies. In the USA, irrigated catheters are used nearly always, mostly with contact force sensing. We used conventional catheters.
The aim. To analyze the complications in 1000 consecutive radiofrequency catheter ablations of atrial fibrillation.
Results and discussion. Non-irrigated 4 mm tip ablation catheters and two venous punctures were used. In total, 32 (3.2%) complications were observed. Pericardial tamponade was observed in 6 cases (0.6%), pericardial effusion in 7 (0.7%), pericardial puncture without effusion in 1 (0.1%), pericarditis in 1 (0.1%), complete atrioventricular (AV) block in 2 (0.2%), transient AV block in 1 (0.1%), stroke in 2 (0.2%), diaphragm paresis with pneumonia in 1 (0.1%), femoral artery aneurysm in 6 (0.6%), femoral hematoma requiring blood transfusion in 2 (0.2%), arteriovenous fistula in 2 (0.2%), hematuria in 1 (0.1%).
Similar frequency of iatrogenic AV block was reported in the literature.
There were 26 (3.4%) complications during 794 primary procedures. After 206 repeated procedures, we observed 2 femoral hematomas, 2 femoral artery aneurysms, 1 arteriovenous fistula and 1 complete AV block – a total of 6 (2.9%) complications.
In several reports the incidence of life-threatening complications was lower than that in our study. However, the total number of complications in our group is at the level of the best results, despite the fact that we do not use irrigated catheters, esophageal temperature probes and endovascular ultrasound probes.
Conclusions. The technique that we use is as safe as other methods of AF radiofrequency catheter ablation.
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Suorsa, Veijo T. "Ultrasound-guided ablation catheter and methods of use." Journal of the Acoustical Society of America 114, no. 1 (2003): 36. http://dx.doi.org/10.1121/1.1601114.
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Kim, Sang Hyun, Jae Min Lee, Kang Won Lee, Sang Hoon Kim, Se Hyun Jang, Han Jo Jeon, Seong Ji Choi, et al. "Irreversible electroporation of the bile duct in swine: A pilot study." Journal of Clinical Oncology 38, no. 4_suppl (February 1, 2020): 541. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.541.
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541 Background: Irreversible electroporation (IRE) is a relatively new ablative method. However, the application of IRE ablation has not been attempted for the treatment of biliary disease. Minimally invasive approach using endoscopic retrograde cholangio-pancreatography (ERCP) can be a novel therapeutic modality for IRE ablation. In this study, we investigated the feasibility and effect of endoscopic IRE for biliary tract in animal model. Methods: A new catheter electrode was developed for endoscopic IRE ablation of biliary tract. The electrode for IRE ablation has two band-shaped electrodes on catheter tip. We performed ERCP and endoscopic IRE ablations on normal common bile duct in 6 Yorkshire pigs. Experimental parameters of IRE were 500V/cm, 1000V/cm and 2000V/cm (under 50 pulses, 100 µs length). Animals were sacrificed after 24 hours and ablated bile duct were collected. H & E stain, immunohistochemistry and western blot were performed. Results: Well-demarcated focal color changes were observed on the mucosa of the common bile duct under all experimental parameters. After IRE ablation, bile duct epithelium was disappeared around ablated area and it showed fibrotic change in H&E stain. Depth of change after IRE was different between each experimental parameters. Apoptotic change of bile duct was localized around mucosa in 500V. Diffuse transmural fibrosis of bile duct was shown after IRE ablation with 2000V. TUNEL immunohistochemistry showed the cell death of bile duct mucosa and submucosa along the electrode. Within 24 hours, no complication was observed in pigs after endoscopic IRE ablation. Conclusions: Endoscopic IRE ablation using ERCP was successfully performed on common bile duct by using catheter-shaped electrode. It can be a potential therapeutic option as minimally invasive ablation for treatment of biliary tumors.
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Wehsener, Sandra, Matthias Heinke, Robin Müssig, Johannes Hörth, Stefan Junk, and Steffen Schrock. "3d print of heart rhythm model with cryoballoon catheter ablation of pulmonary vein." Current Directions in Biomedical Engineering 5, no. 1 (September 1, 2019): 235–38. http://dx.doi.org/10.1515/cdbme-2019-0060.
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AbstractThe visualization of heart rhythm disturbance and atrial fibrillation therapy allows the optimization of new cardiac catheter ablations. With the simulation software CST (Computer Simulation Technology, Darmstadt) electromagnetic and thermal simulations can be carried out to analyze and optimize different heart rhythm disturbance and cardiac catheters for pulmonary vein isolation. Another form of visualization is provided by haptic, three-dimensional print models. These models can be produced using an additive manufacturing method, such as a 3d printer. The aim of the study was to produce a 3d print of the Offenburg heart rhythm model with a representation of an atrial fibrillation ablation procedure to improve the visualization of simulation of cardiac catheter ablation. The basis of 3d printing was the Offenburg heart rhythm model and the associated simulation of cryoablation of the pulmonary vein. The thermal simulation shows the pulmonary vein isolation of the left inferior pulmonary vein with the cryoballoon catheter Arctic Front AdvanceTM from Medtronic. After running through the simulation, the thermal propagation during the procedure was shown in the form of different colors. The three-dimensional print models were constructed on the base of the described simulation in a CAD program. Four different 3d printers are available for this purpose in a rapid prototyping laboratory at the University of Applied Science Offenburg. Two different printing processes were used and a final print model with additional representation of the esophagus and internal esophagus catheter was also prepared for printing. With the help of the thermal simulation results and the subsequent evaluation, it was possible to draw a conclusion about the propagation of the cold emanating from the catheter in the myocardium and the surrounding tissue. It was measured that just 3 mm from the balloon surface into the myocardium the temperature dropped to 25 °C. The simulation model was printed using two 3d printing methods. Both methods, as well as the different printing materials offer different advantages and disadvantages. All relevant parts, especially the balloon catheter and the conduction, are realistically represented. Only the thermal propagation in the form of different colors is not shown on this model. Three-dimensional heart rhythm models as well as virtual simulations allow very clear visualization of complex cardiac rhythm therapy and atrial fibrillation treatment methods. The printed models can be used for optimization and demonstration of cryoballoon catheter ablation in patients with atrial fibrillation.
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Hafez, Mm, Mm Abu-Elkheir, M. Shokier, Hf Al-Marsafawy, Hm Abo-Haded, and M. Abo El-Maaty. "Radiofrequency Catheter Ablation in Children with Supraventricular Tachycardias: Intermediate Term Follow up Results." Clinical Medicine Insights: Cardiology 6 (January 2012): CMC.S8578. http://dx.doi.org/10.4137/cmc.s8578.
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The Purpose of the Study Radiofrequency (RF) catheter ablation represents an important advance in the management of children with cardiac arrhythmias and has rapidly become the standard and effective line of therapy for supraventricular tachycardias (SVTs) in pediatrics. The purpose of this study was to evaluate the intermediate term follow up results of radiofrequency catheter ablation in treatment of SVT in pediatric age group. Methods A total of 60 pediatric patients (mean age = 12.4 ± 5.3 years, ranged from 3 years to 18 years; male: female = 37:23; mean body weight was 32.02 ± 12.3 kg, ranged from 14 kg to 60 kg) with clinically documented SVT underwent an electrophysiologic study (EPS) and RF catheter ablation at Children's Hospital Mansoura University, Mansoura, Egypt during the period from January 2008 to December 2009 and they were followed up until October 2011. Results The arrhythmias included atrioventricular reentrant tachycardia (AVRT; n = 45, 75%), atrioventricular nodal reentrant tachycardia (AVNRT; n = 6, 10%), and atrial tachycardia (AT; n = 9, 15%). The success rate of the RF catheter ablation was 93.3% for AVRT, 66.7% for AVNRT, and 77.8% for AT, respectively. Procedure-related complications were infrequent (7/60, 11.7%), (atrial flutter during RF catheter ablation (4/60, 6.6%); ventricular fibrillation during RF catheter ablation (1/60, 1.6%); transient complete heart block during RF catheter ablation (2/60, 3.3%)). The recurrence rate was 8.3% (5/60) during a follow-up period of 34 ± 12 months. Conclusion RF catheter ablation is an effective and safe method to manage children with SVT.
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Reynolds, Matthew R., Guy David, Candace Gunnarsson, Jamie L. March, and Steven C. Hao. "The Effects of Catheter Ablation Therapy on Medication Use and Expenditures in Patients with Atrial Fibrillation." Journal of Health Economics and Outcomes Research 2, no. 1 (October 1, 2014): 15–28. http://dx.doi.org/10.36469/9881.
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Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia encountered in clinical practice. Catheter ablation has become an important treatment option for many AF patients. Catheter ablation has been hypothesized to reduce the need for continued medical therapy for patients with AF, but there are few empirical data which demonstrate this. Objective: The objective of this study was to estimate the impact of catheter ablation on antiarrhythmic drug (AAD) utilization and total drug expenditures among AF patients. Methods: A retrospective analysis using the Truven Health Analytics MarketScan® Research Database was performed. Patients with AF and a catheter ablation procedure who had continuous enrollment in the database 6 months prior to their first ablation and a minimum of 1-year follow-up post first ablation were compared to AF patients who were treated with AADs and not ablation. Propensity matching was used to account for baseline differences between groups, and multivariable regression models adjusted for patient characteristics and baseline healthcare resource utilization. Sub-analyses were performed for patients age ≥65. Results: AF patients treated with catheter ablation had significantly lower AAD utilization and total prescription drug costs than those treated with AADs only. These results persisted for the subset of patients age ≥65. The effects were strongest in the matched sample, where approximately 30% of ablation patients discontinued use of rhythm medication after receiving catheter ablation. Per-patient total medication expenditures were reduced by $800 to $1,200 per year in the matched sample. Conclusion: Catheter ablation for AF reduced AAD utilization and total prescription drug expenditures in a sustainable fashion up to 3 years post ablation. This reduction was consistent and significant in both the non-Medicare and Medicare populations.
Dissertations / Theses on the topic "CATHETER ABLATION/methods"
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Santos, André Meirelles dos. "Análise do efeito do resfriamento da via excretora durante termoablação com radiofreqüência em rim de porco." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5153/tde-14032007-194455/.
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A ablação de tumores renais com radiofreqüência tem se tornado uma alternativa cada vez mais atraente dentro do arsenal de procedimentos minimamente invasivos. Uma das raras complicações desta forma de tratamento é a lesão térmica do urotélio, desencadeando fístulas urinárias, hidronefrose, estenose ureteral e estenose de junção ureteropiélica, em alguns casos, com necessidade de nefrectomia do órgão acometido. Em lesões hepáticas, ablação tumoral muito perto da via biliar pode evoluir com estenose, a menos que haja um resfriamento dos dutos biliares concomitante à aplicação da radiofreqüência. Desta forma, o objetivo deste estudo foi o de propor um processo semelhante no trato urinário, comparando ablações renais próximas ao urotélio, com e sem irrigação do sistema coletor, com soro fisiológico a 2°C, analisando a integridade da via excretora e a eficácia da ablação. Métodos: Oito suínos do sexo feminino foram submetidos à laparotomia, com abertura da bexiga e cateterização de um dos meatos ureterais com cateter de duplo-lúmen, conforme sorteio realizado antes do início do procedimento. Foi realizada aplicação de radiofreqüência com um ciclo de oito minutos, regulada para atingir uma temperatura média de 100°C e aplicada com uma agulha deflagrada com um centímetro de exposição, sendo produzida uma lesão superficial no terço médio do rim. O grau de profundidade da agulha foi monitorado pelo uso de ultra-som intra-operatório. No total, foram realizadas duas lesões em cada animal, uma no rim sem cateter ureteral, e outra em um rim exposto ao resfriamento da via excretora com soro fisiológico a 2°C, circulando a 30 ml/min. Os animais foram sacrificados no décimo-quarto dia de pósoperatório. Resultados: Os maiores diâmetros da lesão criada pela radiofreqüência e o aspecto radiológico da via excretora, obtido por meio de pielografia ascendente bilateral, foram comparados e não houve diferença significativa entre os rins tratados, estando ou não expostos ao resfriamento da via excretora. Conclusão: O resfriamento da via excretora durante ablação com radiofreqüência não alterou a necrose de coagulação gerada, tampouco afetou a integridade da via excretoraRenal tumor ablation has become quite an attractive alternative among minimally invasive procedures. One of the few complications of this new technology is thermal damage to the urothelium, causing urinary fistula, hydronephrosis and ureteral and ureteropelvic junction obstruction. Some cases required a nephrectomy. In hepatic lesions, tumoral ablation near biliary ducts may cause stenosis, unless intraductal cooling of the main ducts is done simultaneously with radiofrequency ablation. This study proposed using a similar process in the urinary tract, comparing renal ablation near the urothelium, with and without cooling the collecting system with 2°C 0.9% saline, and analyzing the excretory ducts\' integrity and the ablation efficiency. Methods: Eight female porcines were submitted to laparotomy and bladder opening, having one of the ureteral meatus catheterized with a double-lumen catheter according to a random selection made prior to the procedure. An eight minute radiofrequency cycle, planned to achieve a mean temperature of 100°C, was done using a needle with one centimeter of exposition, creating a superficial lesion in the renal cortex. The needle depth was monitored by ultrasound during surgery. Two lesions were made in each animal, one in a kidney without a catheter and the other in a kidney cooled with 2°C 0.9% saline circulating at 30 ml/ min. The pigs were put to death two weeks after the procedure. Results: The largest diameters were determined for each lesion and bilateral retrograde pielography was done to check the radiological aspect of the urinary ducts. No significant difference between the kidneys was observed, regardless of whether the urinary system had been cooled or not. Conclusion: Cooling the excretory ducts during radiofrequency ablation did not alter the coagulation necrosis, nor did it affect the integrity of the urinary collecting system.
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Melo, Sissy Lara. "Ablação do istmo cavo-tricuspídeo para controle do flutter atrial: estudo prospectivo e randomizado comparando eficácia e segurança de cateter irrigado com cateter de 8 mm." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-20102005-150207/.
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O cateter irrigado foi comparado com o de 8 mm para ablação com radiofrequência do istmo cavo-tricuspídeo(Ist-CT). Foram randomizados 52 pacientes portadores de flutter atrial típico para ablação com cateter irrigado(grupoI) ou com cateter de 8 mm(grupo II). O bloqueio do Ist-CT foi obtido em 51 pacientes. Não houve diferença estatística em relação aos parâmetros de aplicação de RF entre os dois grupos. A ablação do Ist-CT com cateter irrigado versus cateter de 8mm foi igualmente eficaz e segura no controle do flutter atrial típico.A 4-mm cooled tip catheter was compared to an 8-mm tip catheter to cavotricuspid isthmus(CTI) ablation. This prospective study enrolled 52 patients with typical atrial flutter to ablation with a closed cooled-tip catheter(group1) or an 8-mm tip catheter. Radiofrequency(RF) applications were performed to achieve complete CTI block wich was achieved in 51 patients. No significant differences were found in the procedure parameters. CTI ablation with an irrigated tip catheter versus an 8-mm tip catheter was equally effective and satisfactorily safe for ablation of typical atrial flutter.
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Venancio, Ana Claudia. "Avaliação da viabilidade da técnica de acesso ao espaço epicárdico por punção transatrial para ablação epicárdica por catete." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-18022011-152822/.
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Fundamentos O acesso percutâneo ao espaço pericárdico pela via transatrial poderia ser uma alternativa ao acesso subxifóide para o mapeamento e ablação de fibras miocárdicas subepicárdicas. O objetivo deste estudo foi avaliar a viabilidade de alcançar o espaço pericárdico normal através do apêndice auricular direito (AAD) por acesso transvenoso. Métodos e Resultados - Um sistema Mullins (8F), originalmente desenvolvido para alcançar o átrio esquerdo (AE) por punção transeptal foi utilizado neste estudo para transfixar o AAD (16) ou AE (1) em 17 suínos, com uma média de 26,9 ± 2,6 kg, e alcançar o espaço pericárdico normal. Um cateter 7F quadripolar com eletrodo distal com 4 ou 8 mm foi introduzido no espaço pericárdico para aplicações de radiofrequência. Em 15 (88%) animais o procedimento foi realizado sem instabilidade hemodinâmica (PA média inicial = 80,4 ± 11.7 mmHg; PA média final = 86,8 ± 9.7 mmHg, p = 0,11). Foi identificado e aspirado derrame pericárdico discreto (28,9 ± 27.6 ml/animal) durante o procedimento. O espaço pericárdico foi acidentalmente acessado por punção do ventrículo direito (VD) em um animal e por punção do anel da valva tricúspide em outro. Ambos apresentaram sangramento xii pericárdico importante e tamponamento cardíaco. Um dispositivo para oclusão do orifício de perfuração foi testado com sucesso em três porcos, dois no AD e um no VD, sem ocorrência de derrame pericárdico significativo. Conclusões O acesso transatrial ao espaço pericárdico pode ser potencialmente útil para mapeamento e ablação de arritmias cardíacas, bem como para drenagem imediata de um tamponamento cardíaco agudoBackground A transvenous access to the pericardial space could provide a convenient route to map and ablate subepicardial myocardial fibers. The aim of this study was to evaluate the feasibility of reaching the normal pericardial space through the right atrial appendage (RAA) by transvenous access. Methods and Results An 8F Mullins system was used to transfix the right atrium (16) and left atrium (1) in 17 pigs with a mean of 26.9 ± 2.6 kg. A 7F quadripolar catheter with 4 or 8 mm distal tip electrode was introduced into the pericardial space to perform epicardial radiofrequency lesions. The pericardial space was successfully reached in 15 (88%) animals without hemodynamic instability (initial mean BP 80.4 ± 11.7 mmHg; final 86.8 ± 9.7 mmHg, p= 0,11). However, a mild pericardial serohemorrhagic effusion was identified and aspirated in all the animals (28.9 ± 27.6 ml/pig) during the procedure. The pericardial space was accidentally accessed through the right ventricle (RV) in one animal and through the tricuspid annulus in another, which presented important pericardial bleeding and cardiac tamponade. The hypothesis that an occlusion device could be useful to close the created atrial xiv orifice was tested successfully in thee pigs (two at RAA and one at RV) and without significant pericardial bleeding. Conclusions The right atrial appendage route might be potentially useful to access the normal pericardial space for mapping and ablating cardiac arrhythmias as well as to drain promptly an acute tamponade
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Filho, Carlos Alberto Cordeiro de Abreu. ""Avaliação dos resultados a médio prazo da ablação cirúrgica por radiofreqüência da fibrilação atrial permanente em pacientes portadores de valvopatia mitral reumática"." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5156/tde-17082005-113744/.
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A ablação cirúrgica por radiofreqüência (RF) é uma nova técnica para tratar a fibrilação atrial (FA) permanente. O objetivo deste estudo é avaliar a eficácia da ablação cirúrgica por RF da FA permanente em pacientes com valvopatia mitral reumática (VMR). Entre Fevereiro de 2002 e Abril de 2003, 70 pacientes com FA permanente e VMR foram submetidos à operação da valva mitral associada à ablação por RF da FA (Grupo A); ou à operação da valva mitral isolada (Grupo B). No seguimento pós-operatório foram avaliados: a reversão para o ritmo sinusal (RS) e a contratilidade atrial. Após 12 meses de seguimento, os índices de reversão para o RS e de restabelecimento da contratilidade atrial foram significativamente superiores no Grupo A. A ablação cirúrgica por RF é eficaz para o tratamento da FA permanente em pacientes com VMRRadiofrequency ablation is a new surgical technique to treat permanent atrial fibrillation. The aim of this study was to evaluate the effectiveness of the (RF) ablation for the treatment of permanent AF in patients with rheumatic mitral valve (MV) disease. Between February 2002 and April 2003, 70 patients with permanent AF and rheumatic MV disease were assigned to undergo a MV surgery associated with RF ablation (Group A), or MV surgery alone (Group B). After 12 months of follow-up, the cumulative rates of sinus rhythm conversion and atrial transport function restoration were higher in Group A.The RF ablation is effective for treating permanent AF associated with rheumatic MV disease
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"Candida albicans agglutinin-like sequence (ALS) gene expression in an in vitro dynamic catheter adhesion model." 2010. http://library.cuhk.edu.hk/record=b5896661.
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Jin, Dawei.Thesis (M.Phil.)--Chinese University of Hong Kong, 2010.
Includes bibliographical references (leaves 83-93).
Abstracts in English and Chinese.
ABSTRACT (IN CHINESE) --- p.ii
ABSTRACT (IN ENGLISH) --- p.iv
ACKNOWLEDGEMENTS --- p.vii
CONTENTS --- p.ix
LIST OF TABLES --- p.vxiii
LIST OF FIGURES --- p.xiv
LIST OF ABBREVIATIONS --- p.xvi
Chapter CHAPTER I --- INTRODUCTION --- p.1
Chapter 1.1 --- Biology of C. albicans --- p.2
Chapter 1.1.1 --- Taxonomy --- p.2
Chapter 1.1.2 --- Basic cell biology --- p.2
Chapter 1.1.2.1 --- Cell cycle and phenotypic switch --- p.2
Chapter 1.1.2.2 --- Cell wall --- p.3
Chapter 1.1.3 --- "Morphological, culture and biochemical characteristics" --- p.4
Chapter 1.1.4 --- Genomics --- p.5
Chapter 1.1.5 --- Pathogenecity --- p.6
Chapter 1.2 --- Catheter-related bloodstream infections (CRBSI) caused by C. albicans --- p.7
Chapter 1.2.1 --- Intravenous catheter type --- p.7
Chapter 1.2.2 --- Epidemiology of CRBSI caused by C. albicans --- p.8
Chapter 1.2.3 --- Pathogenesis of intravascular catheter-related infections --- p.9
Chapter 1.2.4 --- Diagnosis of catheter-related infections --- p.10
Chapter 1.2.5 --- Prevention and control --- p.11
Chapter 1.3 --- Mechanism of C. albicans adhesion to catheters --- p.12
Chapter 1.3.1 --- The definition of microbial adhesion --- p.12
Chapter 1.3.2 --- Relationship between microbial adhesion and biofilm formation --- p.12
Chapter 1.4 --- Agglutinin-like sequence (ALS) gene family of C. albicans --- p.14
Chapter 1.4.1 --- Members of ALS gene family --- p.14
Chapter 1.4.2 --- Chromosomal location of ALS genes --- p.14
Chapter 1.4.3 --- ALS gene organization --- p.14
Chapter 1.4.3.1 --- Three-domain structure of ALS genes --- p.15
Chapter 1.4.3.2 --- Characterization of ALS genes. --- p.15
Chapter 1.4.4 --- ALS gene allelic variation --- p.17
Chapter 1.5 --- Experimental models for catheter adhesion study of C. albicans --- p.17
Chapter 1.5.1 --- "Static adhesion model for C, albicans" --- p.18
Chapter 1.5.1.1 --- Advantage of static adhesion model --- p.19
Chapter 1.5.1.2 --- Limitation of static adhesion model --- p.19
Chapter 1.5.2 --- Dynamic adhesion model for C. albicans --- p.19
Chapter 1.5.2.1 --- Advantage of dynamic adhesion model --- p.20
Chapter 1.5.2.2 --- Limitation of dynamic adhesion model --- p.20
Chapter 1.5.3 --- Quantification methods of adherent cells --- p.21
Chapter 1.5.4 --- ALS gene expression study in the in vitro model --- p.22
Chapter 1.6 --- Aim of study --- p.22
Chapter CHAPTER II --- MATERIALS & METHODS --- p.24
Chapter 2.1 --- Strains used in this study --- p.25
Chapter 2.2 --- Design of an in vitro dynamic adhesion model for C. albicans --- p.26
Chapter 2.2.1 --- Flask --- p.26
Chapter 2.2.2 --- Peristaltic pump --- p.26
Chapter 2.2.3 --- Glass tube and vascular catheters. --- p.27
Chapter 2.2.4 --- Sterility check of in vitro dynamic adhesion model --- p.27
Chapter 2.3 --- Construction of C. albicans growth curve --- p.27
Chapter 2.4 --- Measurement of C. albicans adhesion to catheters --- p.29
Chapter 2.5 --- Detection of C. albicans ALS genes --- p.30
Chapter 2.5.1 --- DNA extraction of C. albicans --- p.30
Chapter 2.5.2 --- ALS primers design --- p.31
Chapter 2.5.3 --- PCR reaction --- p.32
Chapter 2.5.4 --- Gel electrophoresis --- p.32
Chapter 2.5.5 --- Purification of PCR products --- p.33
Chapter 2.6 --- Construction of E. coli plasmid containing gene --- p.34
Chapter 2.6.1 --- Ligation using the pGEM®-T Easy Vector --- p.34
Chapter 2.6.2 --- Preparation of E. coli DH5a electro-competent cells --- p.35
Chapter 2.6.3 --- Clean up of DNA ligation reaction for electro-transformation --- p.36
Chapter 2.6.4 --- Electro-transformation of E. coli DH5a electro-competent cells --- p.37
Chapter 2.6.5 --- Blue / white screening for positive transformation of E. coli DH5a. --- p.37
Chapter 2.6.6 --- Extraction of plasmid containing ALS1 gene --- p.39
Chapter 2.6.7 --- Plasmid validation by PCR and gel electrophoresis --- p.39
Chapter 2.6.8 --- Serial dilution of plasmid solutions for ALS1 standard curve construction --- p.40
Chapter 2.7 --- C. albicans ALS1 gene expression in dynamic adhesion model --- p.41
Chapter 2.7.1 --- Design of real-time PCR primers specific for C. albicans ALS1 --- p.41
Chapter 2.7.2 --- Validation of primers specificity --- p.42
Chapter 2.7.3 --- RNA extraction of C. albicans cells adhered on catheters --- p.43
Chapter 2.7.4 --- Complementary DNA (cDNA) synthesis --- p.45
Chapter 2.7.5 --- Quantitative real-time RT-PCR --- p.46
Chapter 2.8 --- Statistical analyses --- p.48
Chapter CHAPTER III --- RESULTS --- p.49
Chapter 3.1. --- Validation of the in vitro dynamic adhesion model for C. albicans --- p.50
Chapter 3.2. --- C. albicans growth curve construction --- p.50
Chapter 3.3. --- Measurement of C. albicans adhesion on catheters --- p.50
Chapter 3.4. --- Detection of C. albicans SC5314 ALS genes --- p.52
Chapter 3.5. --- Validation of E. coli plasmid containing ALS1 gene --- p.54
Chapter 3.6. --- C. albicans ALS 1 gene expression in dynamic adhesion model --- p.54
Chapter 3.6.1. --- Specificity validation of ALS1 real-time primers --- p.55
Chapter 3.6.2. --- Quantitative real-time RT-PCR --- p.55
Chapter CHAPTER IV --- DISCUSSION --- p.57
Chapter 4.1 --- Experimental design of the in vitro dynamic adhesion model --- p.58
Chapter 4.1.1 --- Advantages of this in vitro dynamic adhesion model --- p.58
Chapter 4.1.2 --- Limitation of this in vitro dynamic adhesion model --- p.58
Chapter 4.1.3 --- Catheter arrangement inside the glass tube --- p.60
Chapter 4.1.4 --- Reproducibility of experiments in the model --- p.62
Chapter 4.1.5 --- Identification of potential contamination in the model --- p.63
Chapter 4.1.6 --- Advantages of removing method for C. albicans adherent cells --- p.64
Chapter 4.1.7 --- Limitation of removing method for C. albicans adherent cells --- p.64
Chapter 4.1.8 --- Limitation of statistical analysis --- p.66
Chapter 4.1.9 --- Primers design --- p.67
Chapter 4.1.9.1 --- Primers of C. albicans ALS gene detection --- p.67
Chapter 4.1.9.2 --- Validation of ALS 1 real-time primers specificity --- p.69
Chapter 4.2 --- C. albicans adhesion to catheters --- p.70
Chapter 4.2.1 --- Theoretical explanation of C. albicans adhesion to different catheters --- p.71
Chapter 4.3 --- C. albicans ALS gene expression --- p.74
Chapter 4.3.1 --- Functions of Als proteins --- p.75
Chapter 4.3.1.1 --- Adhesive functions --- p.75
Chapter 4.3.1.2 --- Other functions in C. albicans pathogenesis --- p.75
Chapter 4.3.2 --- Analysis of ALS1 gene expression pattern in the in vitro model --- p.76
Chapter 4.4 --- Clinical application of our study --- p.78
Chapter 4.5 --- Future study --- p.80
Chapter 4.6 --- Conclusion --- p.81
REFERENCES --- p.83
Books on the topic "CATHETER ABLATION/methods"
1
Huang, Shoei K., and Mark A. Wood. Catheter ablation of cardiac arrhythmias. 2nd ed. Philadelphia, PA: Elsevier Saunders, 2011.
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2
Rider), Betts Tim (Tim, and Rajappan Kim, eds. Cardiac electrophysiology and catheter ablation. Oxford: Oxford University Press, 2010.
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3
Practical guide to catheter ablation of atrial fibrillation. Chichester, West Sussex: John Wiley and Sons, Inc., 2016.
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4
Hong, Kelvin. Percutaneous tumor ablation: Strategies and techniques. New York: Thieme, 2011.
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5
Borggrefe, Martin. Catheter ablation of ventricular tachycardia in patients with structural heart disease. Armonk, N.Y: Futura Pub. Co., 2000.
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6
L, Levine R., ed. A practical manual of hysteroscopy and endometrial ablation techniques: A clinical cookbook. London: Taylor & Francis, 2004.
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8
P, Zipes Douglas, ed. Catheter ablation of arrhythmias. Armonk, NY: Futura Pub. Co., 1994.
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9
Michel, Haissaguerre, and Zipes Douglas P, eds. Catheter ablation of arrhythmias. 2nd ed. Armonk, NY: Futura Pub. Co., 2002.
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10
Catheter ablation of cardiac arrhythmias. Philadelphia, PA: Saunders Elsevier, 2005.
Find full textBook chapters on the topic "CATHETER ABLATION/methods"
1
Klein, Andres C., Riccardo Proietti, and Félix Ayala-Paredes. "Complications of Radiofrequency Catheter Ablation and Prevention Methods." In Cardiac Electrophysiology Without Fluoroscopy, 191–98. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-16992-3_15.
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2
Andrade, J. G., M. W. Deyell, and L. Macle. "Catheter Ablation for Atrial Fibrillation (Methods)." In Encyclopedia of Cardiovascular Research and Medicine, 553–65. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-12-809657-4.99784-9.
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3
Andrade, J. G. "OBSOLETE: Catheter Ablation for Atrial Fibrillation (Methods)." In Reference Module in Biomedical Sciences. Elsevier, 2018. http://dx.doi.org/10.1016/b978-0-12-801238-3.99784-8.
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Deisenhofer, Isabel. "Management of specific supraventricular tachycardias." In ESC CardioMed, 2063–66. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0482.
Full textAbstract:
Therapy of specific supraventricular tachycardias requires a treatment strategy which is adjusted to the particular supraventricular tachycardia. The choice exists between rhythm control, and here more specifically between medical rhythm control, which might be of relative efficacy only and is hampered by side effects of antiarrhythmic drugs, and catheter ablation. Catheter ablation is nowadays a very effective and safe method of definitive cure from many arrhythmias—and thus is the gold standard of treatment. For rate control, which is less attractive in supraventricular tachycardias, the same choice between medical therapy and catheter ablation exists, this time, however, involving catheter ablation of the atrioventricular node only.
Conference papers on the topic "CATHETER ABLATION/methods"
1
NOGAMI, AKIHIKO. "CATHETER ABLATION OF PRIMARY VENTRICULAR FIBRILLATION: MAPPING METHODS AND THE MECHANISM OF CATHETER ABLATION." In Proceedings of the 31st International Congress on Electrocardiology. WORLD SCIENTIFIC, 2005. http://dx.doi.org/10.1142/9789812702234_0220.
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2
Yu, Kaihong, Ren Takahashi, and Makoto Ohta. "Development of the Working Fluid With Blood Viscosity for Evaluating Ablation Catheter in In Vitro System." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-65975.
Full textAbstract:
The purpose of this study was to develop a working fluid with the proper viscosity to mimic blood flow to evaluate an ablation catheter. We proposed a working fluid that matches the blood viscosity, using glycerol-saline solution or xanthan gum (XG)-saline solution. We compared the two solution mixtures at various concentrations (for glycerol-saline solution, 10%, 30%, and 50%; for XG-saline solution, 0.10%, 0.11%, 0.12%, and 0.13%) by measuring their temperature dependence on viscosity. To test the developed working fluids, RF ablations were performed with both solutions, and the flow around the catheter during ablation was observed by particle image velocimetry (PIV) method. In addition, to test the efficacy of the solution mixtures, myocardium was observed after it was soaked separately in the two solution mixtures. The viscosity of both kinds of solution mixtures increased at higher concentrations and decreased with increasing temperatures. At 37°C, the viscosities of 50% glycerol-saline solution and 0.11%–0.13% XG-saline solution were 3–4 mPa·s, a value that is similar to the viscosity of blood. The upward flow resulting from heat convection by ablation was observed around the catheter in the PIV analysis using an in vitro model without flow. The solution mixture with the higher viscosity flowed at a lower velocity around the catheter, and the myocardium soaked in 50% glycerol-saline solution shrunk into a black and tough tissue. On the other hand, the myocardium soaked in XG-saline solution showed no change in color or shape. In conclusion, the XG-saline solution is a superior option for evaluating ablation catheters.
3
Hu, Zhenkai, Jongseok Won, Youngjin Moon, Sanghoon Park, and Jaesoon Choi. "Design of a Robotic Catheterization Platform With Use of Commercial Ablation Catheter." In 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3347.
Full textAbstract:
Cardiovascular diseases including atherosclerosis, thrombosis, aneurysm and arrhythmia remain the major cause of mortality in developed countries, accounting for 34% of deaths each year [1]. Commonly used minimally invasive vascular intervention with using catheters leads to higher success rate than open surgery [2]. Integrating robotic technologies into active control of catheters in teleoperation manner has promised to reduce radiation exposure to surgeons and improve accuracy during electro-physiological (EP) procedures [1]. Common used commercial robotic EP catheter platforms such as Sensei (Hansen Medical Inc., USA) and Niobe (Stereotaxis Inc., USA) are usually composed of a catheter driver (slave side) which can be remotely controlled by a console operator (master side). However, the Sensei catheters are more rigid and bigger than standard catheters because of their two-layer-sheath structure; and Magnetic Niobe systems are huge and expensive. In this paper, we propose a mechanism of remote-driving catheterization platforms in which a commercial tip-steerable ablation catheter (St. Jude Medical Inc., USA) (Fig. 1) is manipulated by a catheter driver in three degree of freedoms (DOF) (insertion/withdrawal, rotation and tip deflection). In addition, we also present the design of the control software based on Object-Oriented Programming (OOP) method which is expected to give the other researchers a guide line during robotic catheter design.
4
Crews, John H., and Gregory D. Buckner. "Multi-Objective Design Optimization of a Shape Memory Alloy Actuated Robotic Catheter." In ASME 2011 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. ASMEDC, 2011. http://dx.doi.org/10.1115/smasis2011-5037.
Full textAbstract:
In this paper, we present a method for optimizing the design of a shape memory alloy (SMA) actuated robotic catheter. The robotic catheter is designed for use in endocardial ablation procedures, where “trackability” (bending flexibility) and “pushability” are desirable but conflicting catheter traits, leading to a multi-objective optimization problem. The catheter uses SMA tendons for internal actuation, which create a bending moment about a central structure. The design of SMA actuators is often non-intuitive and complicated due to the material’s hysteretic dependence on stress and temperature. The modeling and design difficulties increase when considering antagonistic SMA actuation, which is the case for the robotic catheter. The catheter is optimized using a genetic algorithm coupled with COMSOL Multiphysics Modeling and Simulation software. The objective functions are formulated in order to improve bending flexibility and pushability. Bending flexibility is quantified by radius of curvature. Pushability is a more subjective characteristic that depends on axial stiffness and friction, but for optimization purposes, it is quantified using axial stiffness and the surface area of the catheter. Several design variables that affect the catheter behavior are considered; these include the SMA tendon diameter and its pre-strain, the offset of the SMA tendon from the neutral axis of the central structure, and the central structure’s diameter and elastic modulus.
5
Sun, Deyu, Maryam E. Rettmann, Douglas Packer, Richard A. Robb, and David R. Holmes. "Simulated evaluation of an intraoperative surface modeling method for catheter ablation by a real phantom simulation experiment." In SPIE Medical Imaging, edited by Robert J. Webster and Ziv R. Yaniv. SPIE, 2015. http://dx.doi.org/10.1117/12.2082478.
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