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Journal articles on the topic 'Catheter-related blood stream infection (CRBSI)'

Author: Grafiati
Published: 11 December 2022
Last updated: 19 July 2025

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1

Khan, Mohammad Ashikur Rahman, Md Nizamuddin Chowdhury, Md Nazrul Islam, Mohammad Ehasun Uddin Khan, ASM Tanim Anwar, and Md Saidur Rahman. "Hemodialysis Catheter-Related Blood Stream Infection: Rates, Risk Factors And Pathogens." Journal of Dhaka Medical College 30, no. 1 (2023): 3–8. http://dx.doi.org/10.3329/jdmc.v30i1.56896.

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Background: Central venous catheters (CVC) are an important means of delivering hemodialysis (HD) to patients who require immediate initiation of dialysis. Haemodialysis (HD) catheter-related bloodstream infections (CRBSIs) are a major complication of long-term catheter use in HD. Aims: This study was conducted to identify the rates, risk factors and spectrum of infecting organisms of Hemodialysis catheter-related blood stream infection (CRBSI). Methods: This prospective Observational study was carried out in the Department of Nephrology, Dhaka Medical College Hospital, Dhaka during January 20
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2

Subramanyam, Tanuja Nambakam, and Girish P. Vakrani. "Hemodialysis catheter related blood stream infections." International Journal of Research in Medical Sciences 6, no. 2 (2018): 562. http://dx.doi.org/10.18203/2320-6012.ijrms20180298.

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Background: Hemodialysis catheter related blood stream infection (CRBSI) is common cause for sepsis in hemodialysis patients with high morbidity and mortality. It has to be diagnosed promptly for early treatment to avoid serious complications including catheter removal. This prospective study was undertaken to study clinical features, to validate use of cultures drawn from different sites for diagnosis and management of hemodialysis catheter related blood stream infection (CRBSI). As there is paucity of data regarding CRBSI, hence the study was undertaken.Methods: All hemodialysis patients wit
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Sawant, Ankita R., and Anita A. Paritekar. "Central venous catheter related blood stream infection in tertiary care hospital." International Journal of Research in Medical Sciences 12, no. 7 (2024): 2449–54. http://dx.doi.org/10.18203/2320-6012.ijrms20241896.

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Background: Central venous catheter-related bloodstream infections (CRBSIs) are associated with significant morbidity and mortality in hospitalized patients. Understanding the incidence and risk factors associated with CRBSIs is crucial for implementing effective preventive strategies. The study aimed to examine the incidence and risk factors associated with central venous CRBSIs in a tertiary care hospital setting. Methods: A prospective observational study was conducted at a tertiary care hospital to investigate the incidence and risk factors of CRBSIs. Patients aged >18 years with a cent
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4

George, Kristin, Soumyabrata Nag, K. L. Gupta, and Shefali Gupta. "CLINICO-MICROBIOLOGICAL SPECTRUM OF HEMODIALYSIS CATHETER-RELATED BLOOD STREAM INFECTIONS: A CONCISE REVIEW." International Journal of Advanced Research 11, no. 10 (2023): 123–29. http://dx.doi.org/10.21474/ijar01/17686.

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The disease burden of chronic kidney disease is increasing worldwide, and with the growing population of patients requiring hemodialysis, more patients are placed on central venous catheters (CVCs). Vascular access infections significantly cause hospitalization and mortality among end-stage renal disease (ESRD) patients. As per the data from the United States, Gram-positive organisms account for almost 56% of the total cases of catheter-related bloodstream infection (CRBSI), in stark contrast to Indian studies showing a dominance of Gram-negative organisms. The prolonged use of non-tunnelled c
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Butt, Dr Batool, Dr Farooq, Dr Naveed Sarwar, Dr Mohsin Qayyum, Dr Mujeeb, and Dr bilal. "Clinical And Microbiological Aspects Of Catheter Related Blood Stream Infection In Dialysis Population And Their Short-Term Outcome." Journal of Infectious Diseases 10, no. 1 (2025): 1–6. https://doi.org/10.52338/joid.2025.4598.

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Objective: To investigate the clinical and microbiological aspects of CRBSIs in the dialysis population of Pakistan and evaluate their short-term outcomes. Study Design: Quantitative, cross-sectional study Place and Duration of Study:Five different dialysis centers /clinics located in four different regions of Pakistan from December 2023-May 2024. Methodology: A multistage cluster sampling technique was employed to select a representative sample of dialysis centers from various provinces in Pakistan. Within each selected dialysis center, a systematic random sampling method was used to recruit
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6

Hallam, Carole, Tim Jackson, Anu Rajgopal, and Belinda Russell. "Establishing catheter-related bloodstream infection surveillance to drive improvement." Journal of Infection Prevention 19, no. 4 (2018): 160–66. http://dx.doi.org/10.1177/1757177418767759.

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Background: Catheter-related blood stream infections (CRBSI) are an important complication of central venous access devices but are often poorly measured. This article describes the journey of one hospital trust to set up a surveillance process for CRBSI across all specialties of the trust and to reduce CRBSI. Method: Using a locally adapted CRBSI criteria and root cause analysis (RCA) for investigation we identified a number of opportunities for a quality improvement programme. Findings: Over a 5-year period we saw a significant and sustained reduction in the rate of CRBSI from 5 per 1000 cat
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7

Zahra Zahid, Piracha, Mansha Sadia, Naeem Amna, et al. "Contemplating Catheter Induced Blood Stream Infections and Associated Risk Factors in Diverse Clinical Settings: A Comprehensive Review." Journal of Clinical Intensive Care and Medicine 8, no. 1 (2023): 014–23. http://dx.doi.org/10.29328/journal.jcicm.1001044.

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Catheter-Related Bloodstream Infections (CRBSIs) are severe healthcare-associated complication that occurs when bacteria enter the bloodstream through a catheter. The risk of CRBSIs is influenced by various factors. Prolonged catheter placement increases the risk, as each day increases the potential for bacterial colonization and bloodstream infection. Proper aseptic technique and a sterile environment during catheter insertion are essential to minimize infection risk. Stringent infection control measures during insertion, including sterile gloves, thorough hand hygiene, and appropriate skin d
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8

Walshe, Criona M., Kevin S. Boner, Jane Bourke, et al. "Catheter‐related blood stream infection (CRBSI) in TPN patients." Clinical Governance: An International Journal 15, no. 4 (2010): 292–301. http://dx.doi.org/10.1108/14777271011084064.

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9

Hadian, Babak, Azita Zafarmohtashami, and Mahdi Razani. "Catheter-related blood stream infections in hemodialysis patients." Journal of Renal Injury Prevention 9, no. 4 (2020): e34-e34. http://dx.doi.org/10.34172/jrip.2020.34.

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Introduction: Proper care of vascular access in hemodialysis patients is important. Catheter-related bloodstream infection (CRBSI), is a life-threatening complication of hemodialysis. Objectives: Sufficient data about microorganisms and their susceptibility to antibiotics in hemodialysis patients is necessary for handling of CRBSI; therefore, this study performed for better management of patients. Patients and Methods: All hemodialysis patients from March 2015 to March 2018 who had cultures of catheter and blood samples were studied. Clinical records of 122 patients were reviewed for variables
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10

Parameswaran, Ramanathan, Jatan Bahadur Sherchan, Muralidhar Varma D, Chiranjay Mukhopadhyay, and Sudha Vidyasagar. "Intravascular catheter-related infections in an Indian tertiary care hospital." Journal of Infection in Developing Countries 5, no. 06 (2010): 452–58. http://dx.doi.org/10.3855/jidc.1261.

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Introduction: This study had two objectives: 1) to determine the clinical and microbiological profiles of patients developing intravascular catheter-related local (localized catheter colonization and exit site) and systemic infections and their predisposing factors; 2) to study the antibiotic sensitivity patterns of the organisms isolated. Methodology: This case-control study was conducted over 19 months involving 232 patients at a tertiary care hospital. Non-tunneled central venous catheters and midline catheters were the two types studied. Catheter tips were processed using Maki's roll plate
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Dubey, Prachi, Sanjay Varma, Anupam Kujur, and Bhuwan Sharma. "Study of incidence of central line associated blood stream infections in patients admitted in intensive care unit." International Journal of Advances in Medicine 8, no. 9 (2021): 1350. http://dx.doi.org/10.18203/2349-3933.ijam20213167.

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Background: Central venous catheterization is a relatively common procedure in many branches of medicine particularly in anaesthesia and intensive care medicine. Central venous catheters give an easy access for giving drugs as well as for sampling of blood, but they can also be a cause of blood stream infection and sepsis.Methods: Patients who requiring central venous catheter were selected, relevant blood investigations were done before insertion of catheter and after 48 hours after insertion. With the suspicion of new infection, physical examination and laboratory work-ups were carried out t
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Cornacchiari, Marina, Maurizio Gallieni, Antonella Stasi, Maria Giuseppina Ponticelli, Barbara Gidaro, and Carlo Guastoni. "Prevention of Catheter-Related Blood Stream Infections (CRBSI)." Giornale di Tecniche Nefrologiche e Dialitiche 25, no. 3 (2013): 220–24. http://dx.doi.org/10.5301/gtnd.2013.11439.

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13

Piersigilli, Fiammetta, Cinzia Auriti, Andrea Dotta, et al. "Use of Meropenem and Other Antimicrobial Lock Therapy in the Treatment of Catheter-Related Blood Stream Infections in Neonates: A Retrospective Study." Children 9, no. 5 (2022): 614. http://dx.doi.org/10.3390/children9050614.

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(1) Background: Newborns admitted to Neonatal Intensive Care Units (NICUs) often require the placement of central vascular catheters (CVC), which are a major risk factor for hospital infection. Numerous strategies exist to prevent central line-associated blood stream infections (CLABSIs) and catheter-related bloodstream infections (CRBSIs), with only a few offering options to save the catheter when it is impossible to replace. CRBSIs continue to be a major problem for neonates in NICUs. Most CRBSIs are resistant to systemic antibiotics due to the presence of intraluminal bacterial biofilm. The
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Piersigilli, Fiammetta, Cinzia Auriti, Andrea Dotta, et al. "Use of Meropenem and Other Antimicrobial Lock Therapy in the Treatment of Catheter-Related Blood Stream Infections in Neonates: A Retrospective Study." Children 9, no. 5 (2022): 614. http://dx.doi.org/10.3390/children9050614.

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(1) Background: Newborns admitted to Neonatal Intensive Care Units (NICUs) often require the placement of central vascular catheters (CVC), which are a major risk factor for hospital infection. Numerous strategies exist to prevent central line-associated blood stream infections (CLABSIs) and catheter-related bloodstream infections (CRBSIs), with only a few offering options to save the catheter when it is impossible to replace. CRBSIs continue to be a major problem for neonates in NICUs. Most CRBSIs are resistant to systemic antibiotics due to the presence of intraluminal bacterial biofilm. The
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15

Hamada Imam, Mahmoud, and Eman Gamal. "Procalcitonin Level as a Surrogate for Catheter-Related Blood Stream Infection among Hemodialysis Patients." Journal of Vascular Access 18, no. 6 (2017): 498–502. http://dx.doi.org/10.5301/jva.5000765.

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Introduction Catheter-related bloodstream infection (CRBSI) is a frequent complication among hemodialysis patients who usually are presented with nonspecific signs such as fever, rigors, and hypotension. Blood culture will take up to 5 days and antimicrobials will be started. Procalcitonin (PCT) is a valid marker in sepsis. Our goal in this study is to evaluate its usefulness as a diagnostic marker in detecting CRBSI among hemodialysis patients who present with suspected CRBSI. Patients and methods Thirty-one hemodialysis patients with suspected CRBSI were enrolled in this study. PCT level was
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16

Prakash, Richa, Alpana Ohri, Amish Udani, and Uma Sankari Ali. "Survival of Tunneled Double Lumen-Cuffed Catheters in Children on Maintenance Hemodialysis – A Retrospective Cohort Study." Indian Journal of Nephrology 33, no. 5 (2023): 348–55. http://dx.doi.org/10.4103/ijn.ijn_37_22.

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Introduction: Survival of tunneled cuffed catheters (TCC), used widely in children, is complicated by infections and catheter dysfunction. In resource limited settings, where risk of complications could be higher and waiting period for transplantation longer, catheter survival determines patient survival. This study was conducted to determine infection free catheter survival rates, incidence of catheter failure and associated risk factors. Methods: Children <18 years of age receiving maintenance hemodialysis through TCC at nephrology division of a pediatric hospital, over a period of 6 year
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17

Sucy, Sandra C., Dennis Hupka, and Ruth Curchoe. "The Effect of Nursing Interventions on Catheter-related Bloodstream Infections in Patients Receiving Total Parenteral Nutrition Through Peripherally Inserted Central Catheter Lines." Journal of the Association for Vascular Access 10, no. 4 (2005): 199–203. http://dx.doi.org/10.2309/java.10-4-12.

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Abstract Background: Catheter-related blood-stream infection (CRBSI) is a serious and costly complication associated with central venous catheters. Nursing interventions that focus on decreasing bacterial colonization at the insertion site could decrease infection rates. Method: This retrospective study examined CRBSI in patients requiring peripherally inserted central catheters (PICCs) for total parenteral nutrition. One hundred and ninety-two patients with 235 catheters and an average dwell time of 11.5 days participated. Nursing interventions included a chlorhexidine-impregnated sponge dres
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Boonma, Paithoon, Sonchai Hiranniramol, Wilai Aiumpatoomsak, Poonrut Leeyatikun, and Arisara Suwanarit. "Infection control for the Reduction of Catheter Related Blood Stream Infection (CRBSI)." Bangkok Medical Journal 03, no. 01 (2012): 1–6. http://dx.doi.org/10.31524/bkkmedj.2012.02.001.

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19

O'Grady, Naomi P., Mary Alexander, E. Patchen Dellinger, et al. "Guidelines for the Prevention of Intravascular Catheter–Related Infections." Infection Control & Hospital Epidemiology 23, no. 12 (2002): 759–69. http://dx.doi.org/10.1086/502007.

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Background:Although many catheter-related blood-stream infections (CRBSIs) are preventable, measures to reduce these infections are not uniformly implemented.Objective:To update an existing evidenced-based guideline that promotes strategies to prevent CRBSIs.Data Sources:The MEDLINE database, conference proceedings, and bibliographies of review articles and book chapters were searched for relevant articles.Studies Included:Laboratory-based studies, controlled clinical trials, prospective interventional trials, and epidemiologic investigations.Outcome Measures:Reduction in CRBSI, catheter colon
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O'Grady, Naomi P., Mary Alexander, E. Patchen Dellinger, et al. "Guidelines for the Prevention of Intravascular Catheter–Related Infections." Infection Control & Hospital Epidemiology 23, no. 12 (2002): 759–69. http://dx.doi.org/10.1017/s0195941700080577.

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Background:Although many catheter-related blood-stream infections (CRBSIs) are preventable, measures to reduce these infections are not uniformly implemented.Objective:To update an existing evidenced-based guideline that promotes strategies to prevent CRBSIs.Data Sources:The MEDLINE database, conference proceedings, and bibliographies of review articles and book chapters were searched for relevant articles.Studies Included:Laboratory-based studies, controlled clinical trials, prospective interventional trials, and epidemiologic investigations.Outcome Measures:Reduction in CRBSI, catheter colon
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21

Ren, Wei, Jun Jiang, Yan Wang, Yan Jin, Yuan Fang, and Chen Zhao. "Analysis of pathogenic distribution and drug resistance of catheter-related blood stream infection in hemodialysis patients with vein tunneled cuffed catheter." European Journal of Inflammation 19 (January 2021): 205873922110008. http://dx.doi.org/10.1177/20587392211000887.

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The catheter related blood stream infections (CRBSI) in hemodialysis (HD) patients with vein tunneled cuffed catheter (TCC) and misuse of antibiotic in clinical practice seriously affected the prognosis of MHD patients. The present study aimed to investigate the pathogen distribution and drug resistance of CRBSI in HD patients with TCC to guide clinical empirical pharmacy. The clinical data of 75 HD patients with TCC diagnosed with CRBSI between January 2011 and March 2015 were retrospectively collected, and the distribution and drug resistance of pathogens were analyzed. In 75 HD patients wit
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Harnage, Sophie A. "Achieving Zero Catheter Related Blood Stream Infections: 15 Months Success in a Community Based Medical Center." Journal of the Association for Vascular Access 12, no. 4 (2007): 218–24. http://dx.doi.org/10.2309/java.12-4-8.

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Abstract Achieving Zero Catheter Related Blood Stream Infections: 15 Month Success In A Community Based Medical Center. Background and Purpose: Catheter related blood stream infection (CRBSI) is a major cause of patient morbidity, mortality, and cost. Lower CRBSI rates would decrease inpatient length of stay. Project: An innovative central line bundle was developed to reduce CRBSI. An innovative combination of focused nursing practice and product technologies were selected for the bundle and implemented through a defined educational program. Data was collected from thirty-two critical care bed
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Wathanavasin, Wannasit, Jeerath Phannajit, Manorom Poosoonthornsri, et al. "A Randomized Controlled Trial of Comparative Efficacy between Sodium Bicarbonate and Heparin as A Locking Solution for Tunneled Central Venous Catheters Among Patients Requiring Maintenance Hemodialysis." Canadian Journal of Kidney Health and Disease 8 (January 2021): 205435812110460. http://dx.doi.org/10.1177/20543581211046077.

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Background: Sodium bicarbonate (NaHCO3) is one of the promising solutions that has good safety profile and theoretical advantages regarding antimicrobial and antithrombotic properties but there are still limited reports. Objective: To compare the efficacy in lowering rate of catheter loss due to catheter-related thrombosis (CRT) or catheter-related blood stream infection (CRBSI) between sodium bicarbonate and heparin lock in prevalent chronic hemodialysis (HD) patients. Design: A multicenter, randomized, open-label study Setting: In a developing country, Thailand Patients: Chronic HD patients
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Vanholder, R., B. Canaud, R. Fluck, et al. "Catheter-related blood stream infections (CRBSI): a European view." Nephrology Dialysis Transplantation 25, no. 6 (2010): 1753–56. http://dx.doi.org/10.1093/ndt/gfq205.

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Abu Sa'aleek, Mohammad Ali. "The effect of silver-impregnated catheters on catheter colonization and catheter-related bloodstream infection: a comparison between silver-impregnated and standard catheter." International Journal of Research in Medical Sciences 5, no. 5 (2017): 1737. http://dx.doi.org/10.18203/2320-6012.ijrms20171804.

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The use of antimicrobial central catheter is common in clinical practice to prevent catheter colonization, therefore preventing catheter-related blood stream infection (CRBSI). This paper aims to evaluate evidence from the literature in order to illustrate the effectiveness of one of the most common antimicrobial central catheters, chlorhexidine/silver sulfadiazine central venous catheter, in the prevention of bacterial colonization and CRBSI. Several studies have been selected including randomized control trails (RCTs), meta-analysis and systematic review. The seven RCTs included a total numb
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Khan, Saif Ullah, Muhammad Amir, Ali Javed, et al. "COMPARISION OF FREQUENCY OF INFECTION BETWEEN INTERNAL JUGULAR AND FEMORAL VEIN DOUBLE LUMEN HEMODIALYSIS CATHETER IN CHRONIC KIDNEY DISEASE (CKD) PATIENTS." PAFMJ 71, no. 3 (2021): 993–95. http://dx.doi.org/10.51253/pafmj.v71i3.5200.

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Objective: To compare the frequency of infection between internal jugular and femoral vein double lumen haemodialysis catheter in chronic kidney disease (CKD) patients.
 Study Design: Comparative prospective study. Place and Duration of Study: Department of Medicine, Combined Military Hospital, Peshawar, from Jan to Jun 2018.
 Methodology: A total of 400 patients (200 patients in each group) were included in this study. After insertion of catheter the patients were divided into 2 groups, group-A (jugular) and group-B (femoral) by lottery method and followed for development of cathete
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El-Hennawy, Adel S., Elena Frolova, and Wesley A. Romney. "Sodium bicarbonate catheter lock solution reduces hemodialysis catheter loss due to catheter-related thrombosis and blood stream infection: an open-label clinical trial." Nephrology Dialysis Transplantation 34, no. 10 (2019): 1739–45. http://dx.doi.org/10.1093/ndt/gfy388.

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AbstractBackgroundThere is no ideal lock solution that prevents hemodialysis (HD) catheter loss due to catheter-related thrombosis (CRT) and catheter-related bloodstream infection (CRBSI). Catheter loss is associated with increased hospitalization and high inpatient costs. Sodium bicarbonate (NaHCO3) demonstrates anti-infective and anticoagulation properties with a good safety profile, making it an ideal lock solution development target.The objective of this study was to determine the safety and efficacy of using sodium bicarbonate catheter lock solution (SBCLS) as a means of preventing HD cat
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Uchida, Shumpei, Osamu Imataki, Mami Shimatani, Shigeyuki Yokokura, Makiko Uemura, and Norimitsu Kadowaki. "Ultrasound-Guided Catheter Insertion Did Not Decrease Catheter-Related Blood Stream Infection in Hematological Oncology Care Unit." Blood 128, no. 22 (2016): 2394. http://dx.doi.org/10.1182/blood.v128.22.2394.2394.

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Abstract Background: Central venous catheters (CVCs) are necessary for critically ill patients requiring intravenous pharmacological intervention and subsequent parenteral nutritional support. Although CVCs allow delivery of medications and nutritional support that cannot be administered safely through central venous, their use is inevitably associated with adverse events, mechanical complication and catheter-related infection. While ultrasound guide has already been proven to decrease mechanical complications, it is not fully elucidated whether ultrasound guide decrease the risk of catheter-r
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Shintani, Takamichi, Osamu Imataki, Hiroaki Ohnishi, et al. "Incidence of Blood Stream Infection Influenced by Dressing and Clinical Skin Care in a Patient with Neutropenia." Blood 112, no. 11 (2008): 4368. http://dx.doi.org/10.1182/blood.v112.11.4368.4368.

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Abstract Purpose For cancer-bearing patients, especially for patients with hematological malignancies, blood access is a ‘lifeline’ during chemotherapy, in three senses: administration of chemotherapy for the cancer treatment, intravenous supply of nutrients when a patient’s oral intake is decreased, and injection of many agents for supportive care including antibiotics and G-CSF. For these purposes, we usually use a central venous catheter (CVC) at the subclavian portion. Dressing and skin care of the CVC are critical factors influencing the incidence of catheter-related blood stream infectio
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Majewska, K., J. Pałuba, D. Kociszewska, et al. "PP205-SUN CATHETER MANAGEMENT IN HPN PATIENTS WITH CATHETER RELATED BLOOD STREAM INFECTION (CRBSI)." Clinical Nutrition 32 (September 2013): S100. http://dx.doi.org/10.1016/s0261-5614(13)60250-2.

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Sabir, Omer, Nauman Tarif, Sheikh Rizwan, Kashif Rafique, Nabiha Rizvi, and Amanullah Khan. "TEMPORARY HEMODIALYSIS." Professional Medical Journal 22, no. 03 (2015): 287–92. http://dx.doi.org/10.29309/tpmj/2015.22.03.1342.

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Catheter related blood stream infections (CRBSI) in patients undergoinghemodialysis frequently results in significant morbidity and mortality. Attempts at prevention ofCRBSI by catheter lock antibiotics, antibiotic combinations or solutions including Taurolidinehave emerged over years. Objectives: To determine the role of taurolidine lock in presentationof Catheter related infection in hemodialysis. Design: Multicentre un-builded, randomizedcontrolled, non-inferiority trail. Period: Jul 2012 to Dec 2013. Setting: Department of Nephrology,Fatima Memorial Hospital UHS Lahore. Methods: It was a m
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Pillai, Subhash, Aneeta Jacob, Sandhya Prathapan, et al. "Microbiology and clinical outcomes of central venous catheter-related blood stream infections in patients on maintenance hemodialysis." Journal of Medical and Allied Sciences 12, no. 2 (2022): 70. http://dx.doi.org/10.5455/jmas.27564.

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Central venous catheter-related blood stream infection (CRBSI) is a major cause of morbidity and mortality in patients on maintenance hemodialysis. The objective of the study was to assess the microbiology and clinical outcomes of CRBSI in patients on maintenance hemodialysis. This was a retrospective observational study of all the patients with Stage 5 chronic kidney disease on maintenance hemodialysis at Pushpagiri Medical College Hospital who developed CRBSI between 1st January 2019 and 31st December 2020. Out of the 105 CRBSI patients included in the study, 75% had diabetes mellitus while
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Shrestha, Sagar KD, and K. B. Raut. "Role of Ethanol Lock Therapy Vs Heparin Lock In Preventing Infections in Non-Tunneled Hemodialysis Catheters." Journal of Universal College of Medical Sciences 3, no. 4 (2015): 30–36. http://dx.doi.org/10.3126/jucms.v3i4.24266.

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INTRODUCTION: This study aims to determine the rate of catheter related bloodstream infection using intraluminal 70% ethanol lock 20 min prior to initiation of hemodialysis in comparison with heparin lock and also to study adverse events with the use of locks.
 MATERIAL AND METHODS: Out of 196 patients, eligible 128 patients who under went hemodialysis in Tribhuwan University Teaching Hospital, were randomly allocated to 68 jugular catheterization with ethanol lock or heparin lock and 60 femoral catheterization with ethanol lock or heparin lock. 5 patients with jugular catheter with ethan
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Sedhain, Arun, Abja Sapkota, and Narayan B. Mahotra. "Hemodialysis Catheter-Related Infection in a Teaching Hospital of Central Nepal." Journal of Institute of Medicine Nepal 41, no. 2 (2019): 11–16. http://dx.doi.org/10.3126/jiom.v41i2.26541.

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Introduction: Infection of the central venous catheter (CVC) is a major complication seen among patients undergoing hemodialysis. Identifying CVC related infection (CRI) and its risk factors and causative organisms is important for better implementation of preventive strategies.
 Methods: A prospective study was conducted at Chitwan Medical College for duration of 2 years from January 2017to December 2018 among the patients undergoing hemodialysis via CVC. The data collected were related to patients’ demographics, site of catheter insertion, and duration, microbiological data including cu
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Sedhain, Arun, Abja Sapkota, and Narayan B. Mahotra. "Hemodialysis Catheter-Related Infection in a Teaching Hospital of Central Nepal." Journal of Institute of Medicine Nepal 41, no. 2 (2019): 11–16. http://dx.doi.org/10.59779/jiomnepal.1036.

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Introduction: Infection of the central venous catheter (CVC) is a major complication seen among patients undergoing hemodialysis. Identifying CVC related infection (CRI) and its risk factors and causative organisms is important for better implementation of preventive strategies. Methods: A prospective study was conducted at Chitwan Medical College for a duration of 2 years from January 2017 to December 2018 among the patients undergoing hemodialysis via CVC. The data collected were related to patients’ demographics, site of catheter insertion, and duration, microbiological data including cultu
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Labriola, Laura, and Jean-Michel Pochet. "Any use for alternative lock solutions in the prevention of catheter-related blood stream infections?" Journal of Vascular Access 18, no. 1_suppl (2017): S34—S38. http://dx.doi.org/10.5301/jva.5000681.

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The prevention of catheter-related blood stream infections (CRBSI) in hemodialysis (HD) patients remains a challenge because of high morbidity and mortality associated to CRBSI. Alternative locking solutions (ALS) containing an antithrombotic substance with additional antimicrobial or antibiofilm properties (citrate, ethylenediaminetetraacetic acid [EDTA], 70% ethanol, thrombolytics) with or without the addition of molecules with specific antimicrobial activity (antibiotics, taurolidine, paraben-methylene-blue) has been proposed with the aim to prevent or eradicate intraluminal biofilm coloniz
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Öksüz, Lütfiye, N. Gurler, M. Muftuoglu, FD Sargin, and SK Besisik. "Bacillus Cereus catheter related bloodstream infection in a patient in a patient with acute lymphblastic leukemia." Mediterranean Journal of Hematology and Infectious Diseases 4, no. 1 (2012): e2012004. http://dx.doi.org/10.4084/mjhid.2012.004.

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Bacillus cereus infection is rarely associated with actual infection and for this reason single positive blood culture is usually regarded as contamination . However it may cause a number of infections, such catheter-related blood stream infections. Significant catheter-related bloodstream infections (CRBSI) caused by Bacillus spp. are mainly due to B.cereus and have been predominantly reported in immunocompromised hosts1 . Catheter removal is generally advised for management of infection. In this report, catheter-related bacteremia caused by B.cereus in a patient with acute lymphoblastıc leuk
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Dmytriev, Dmytro, Oleksandr Nazarchuk, and Yuliana Babina. "Study of the effectiveness of antimicrobial dressings with chlorhexidine bigluconate in the prevention of catheter-related blood-stream infections in pediatric intensive care units." Perioperaciina Medicina 5, no. 2 (2023): 19–25. http://dx.doi.org/10.31636/prmd.v5i2.3.

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Introduction. Nosocomial infections are risk factors associated with in-hospital mortality. Among other factors, these infections are strongly associated with invasive devices. In pediatric patients, a central venous catheter (CVC) is one of the most common causes of catheter-related bloodstream infection (CRBSI).
 Background. To investigate the effectiveness of antimicrobial chlorhexidine dressings compared with standard dressings in the prevention of central venous catheter-related bloodstream infections.
 Methods. 20 children who were treated in the intensive care unit were random
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39

Zanwar, Saurabh, Anant Ganesh Gokarn, Santhosh Devdas, et al. "Use of Antibiotic Lock for Salvage of Tunneled Central Venous Catheters with Catheter Colonisation and Catheter Related Blood Stream Infection in a Tertiary Care Hematopoietic Stem Cell Transplantation Unit- a Strategy Revisited." Blood 126, no. 23 (2015): 3116. http://dx.doi.org/10.1182/blood.v126.23.3116.3116.

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Abstract Background: Catheter Related Blood Stream Infection (CRBSI ) and catheter colonization (CC) represent a significant problem encountered in hematopoietic stem cell transplantation (HSCT) setting adding to the morbidity, mortality and cost of healthcare in such patients. Unlike non-tunneled central venous catheters (CVCs), the higher complication rates and added cost associated with reinsertion of a tunneled CVC makes it important to devise effective strategies for catheter salvage.We report the incidence of CRBSI and CC of tunneled CVCs in our patients and use of antibiotic locks to sa
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40

Yakasai, Ahmad M., Hamza Muhammad, Garba Iliyasu, et al. "Efficacy of antimicrobial lock solutions in preventing catheter-related blood stream infection in haemodialysis patients: a systematic review and meta-analysis of prospective randomised controlled trials." Southern African Journal of Infectious Diseases 31, no. 3 (2016): 95–102. http://dx.doi.org/10.4102/sajid.v31i3.80.

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Background: Catheter-related blood stream infection (CRBSI) contributes to morbidity and mortality among patients on haemodialysis (HD). We carried out a systematic review and meta-analysis to assess the efficacy of antimicrobial lock solutions (ALS) in preventing CRBSI.Method: Electronic search of randomised controlled trials (RCTs) comparing ALS with other agents was performed up to January 2013. DerSimonian and Laird meta-analysis was performed to obtain pooled relative risk (RR) from which efficacy of ALS and numbers needed to treat (NNT) were calculated. In a restricted analysis, pooled R
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Wang, Jiayi, Xiaofei Peng, Wenqing Yin, Youming Peng, Hong Liu, and Liyu He. "Eradication of Microorganisms Embedding in Biofilm by a Dose-Dependent Urokinase-Based Catheter Lock Solution in Chronic Hemodialysis Patients." Blood Purification 49, no. 5 (2020): 586–96. http://dx.doi.org/10.1159/000505566.

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Introduction: Catheter-related blood stream infection (CRBSI), the most common complication of central vein catheter (CVC), was closely associated with high morbidity and mortality in hemodialysis (HD) patients. Conjunction with systemic antibiotic, antibiotic lock (ABL) is an important therapeutic option to salvage the catheter. With extra antimicrobial and biofilm removing properties, urokinase plasminogen activator (uPA)-based ABL could have a potential role in the treatment of CRBSI. Objective: In this study, we aimed to explore effectiveness of uPA-based (ABL) on microorganisms embedded i
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Rundjan, Lily. "Skin antiseptic choice to reduce catheter-related bloodstream infections." Paediatrica Indonesiana 51, no. 6 (2011): 345. http://dx.doi.org/10.14238/pi51.6.2011.345-50.

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Background The use of vascular access devices (VADs) may put patients at risk for bloodstream infections. Despite infection control prevention methods used in our neonatal unit, mean catheter-related blood stream infection (CRBSI) rates are quite high. One contributing factor for these high infection rates may be the skin antiseptic preparation procedure undertaken prior to intravenous line insertion.Objectives We aimed to reduce CRBRBSI rates by changing to octenidine hydrochloride antiseptic solutions for skin preparation in the neonatal unit at Cipto Mangunkusumo Hospital.Methods Antiseptic
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Mateo-Lobo, Raquel, Javier Riveiro, Belén Vega-Piñero, and José I. Botella-Carretero. "Infectious Complications in Home Parenteral Nutrition: A Systematic Review and Meta-Analysis Comparing Peripherally-Inserted Central Catheters with Other Central Catheters." Nutrients 11, no. 9 (2019): 2083. http://dx.doi.org/10.3390/nu11092083.

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Background: Home parenteral nutrition (HPN) has become a common therapy. There is still controversy regarding the possibility that peripherally inserted central catheters (PICCs) may diminish catheter-related blood stream infection (CRBSI) rates. Methods: We searched the PubMed database for studies reporting the rates of CRBSI with HPN. Study selection was performed independently by three investigators. Disagreements were discussed and resolved by consensus or by arbitration by an author not involved in the search. The National Institutes of Health Quality Assessment Tools was used to assess t
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Majewska, K., D. Kociszewska, J. Pałuba, et al. "PP182-MON CATHETER RELATED BLOOD STREAM INFECTIONS (CRBSI) IN HPN PATIENTS – OCCURRENCE AND OUTCOME." Clinical Nutrition 32 (September 2013): S190. http://dx.doi.org/10.1016/s0261-5614(13)60493-8.

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45

Poletti, Nicola. "Catetere venoso centrale a breve termine e infezioni locali: ancoraggio chirurgico versus 2-octil ciano acrilato." Scenario® - Il Nursing nella sopravvivenza 29, no. 2 (2018): 19–26. http://dx.doi.org/10.4081/scenario.2012.165.

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Introduzione: i Cateteri Venosi Centrali (CVC), forniscono un accesso indispensabile, ma purtroppo il loro uso determina per i pazienti, tra gli altri, un rischio di complicanze infettive locali e sistemiche Catheter Related Blood Stream Infections (CRBSI). In Terapia Intensiva (TI), il rischio è correlato alla gestione asettica del sito cutaneo e al tipo di fissaggio che determina la colonizzazione e la conseguente contaminazione del catetere vascolare da parte di agenti patogeni esterni.
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Choron, Rachel L., Andrew Wang, Kathryn Van Orden, Lisa Capano-Wehrle, and Mark J. Seamon. "Emergency Central Venous Catheterization during Trauma Resuscitation: A Safety Analysis by Site." American Surgeon 81, no. 5 (2015): 527–31. http://dx.doi.org/10.1177/000313481508100538.

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Central venous catheterization (CVC) is often necessary during initial trauma resuscitations, but may cause complications including catheter-related blood stream infection (CRBSI), deep venous thrombosis (DVT), pulmonary emboli (PE), arterial injury, or pneumothoraces. Our primary objective compared subclavian versus femoral CVC complications during initial trauma resuscitations. A retrospective review (2010–2011) at an urban, Level-I Trauma Center reviewed CVCs during initial trauma resuscitations. Demographics, clinical characteristics, and complications including: CRBSIs, DVTs, arterial inj
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Haller, S. M., M. Bevans, E. S. Curnow, and D. Gutierrez. "Suspected catheter related blood stream infection (CRBSI) in hematology stem cell transplant patients: tracking rates and outcomes." Biology of Blood and Marrow Transplantation 10 (February 2004): 100. http://dx.doi.org/10.1016/j.bbmt.2003.12.261.

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48

Tomar, Rampal Singh, Ashish Kr Gupta, and I. D. Khan. "Incidence of catheter-related bloodstream infections after removal of peripherally inserted central catheters in preterm neonates." International Journal of Contemporary Pediatrics 7, no. 2 (2020): 282. http://dx.doi.org/10.18203/2349-3291.ijcp20200018.

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Background: Peripherally inserted central catheter (PICC) have become essential for a safe and reliable long term venous access in all neonatal intensive care units (NICU) for providing long term intravenous fluids and medications. However, they associated with central line blood stream infections (CRBSI) infections and it is postulated that this risk is more on during their removal but the true incidence is not known. The objective was to evaluate the incidence and identify risk factors associated with CRBSI following the PICC removal in preterm neonates.Methods: This was a retrospective coho
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Yousif Salem, Hussein, Maseer Ahmed, Kashif Gulzar, Fakhriya Alalawi, and Amna Alhadari. "Hemodialysis Catheter-related Infections: Incidence, Microbiology and Outcome 5 years of Dubai Hospital Experience." European Journal of Clinical Medicine 2, no. 3 (2021): 111–15. http://dx.doi.org/10.24018/clinicmed.2021.2.3.97.

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Background: The central venous catheters (CVC) has recently become a worldwide commonest technique for vascular access, however; prone to infection and associated with other complications more than other vascular access techniques, such as fistula or graft.
 Objective: To investigate the incidence, the types of micro-organism, the most sensitive and suitable antibiotics, the outcomes associated with CVC infection in chronic hemodialysis patients treated through tunneled CVC.in a single-center population.
 Methods: The records of hemodialysis patients from January 2012 to December 201
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Amy, Tustin, Hartley Karen, Derry David, and Thomas Julian. "P10 Evaluation of existing line-locking practice in central venous catheters of paediatric patients on home parenteral nutrition." Archives of Disease in Childhood 103, no. 2 (2018): e1.14-e1. http://dx.doi.org/10.1136/archdischild-2017-314584.21.

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AimTo review current line-locking practice of central venous catheters (CVCs) to reduce catheter related blood stream infections (CRBSIs) and preserve line integrity in paediatric patients on home parenteral nutrition (HPN), with the secondary aim of producing a concise, evidence-based guideline for use in this cohort and inpatient PN patients as well.MethodAll 19 paediatric HPN patients were reviewed retrospectively over 6 months (January–June 2017). Data was collected from clinic letters, HPN prescriptions and blood cultures. Information gathered per patient:Line lock(s)Infective episode(s)C
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