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1

Shah, Dipen. "Evolution of Force Sensing Technologies." Arrhythmia & Electrophysiology Review 6, no. 2 (2017): 75. http://dx.doi.org/10.15420/aer.2017.8.2.

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In order to improve the procedural success and long-term outcomes of catheter ablation techniques for atrial fibrillation (AF), an important unfulfilled requirement is to create durable electrophysiologically complete lesions. Measurement of contact force (CF) between the catheter tip and the target tissue can guide physicians to optimise both mapping and ablation procedures. Contact force can affect lesion size and clinical outcomes following catheter ablation of AF. Force sensing technologies have matured since their advent several years ago, and now allow the direct measurement of CF betwee
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Shah, Dipen. "Evolution of Force Sensing Technologies." Arrhythmia & Electrophysiology Review 6, no. 2 (2017): 75. http://dx.doi.org/10.15420/aer.2017:8:2.

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In order to improve the procedural success and long-term outcomes of catheter ablation techniques for atrial fibrillation (AF), an important unfulfilled requirement is to create durable electrophysiologically complete lesions. Measurement of contact force (CF) between the catheter tip and the target tissue can guide physicians to optimise both mapping and ablation procedures. Contact force can affect lesion size and clinical outcomes following catheter ablation of AF. Force sensing technologies have matured since their advent several years ago, and now allow the direct measurement of CF betwee
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3

Bickel, Karen, Thorsten Lewalter, Johannes Fischer, et al. "Value of Mini Electrodes for Mapping Myocardial Arrhythmogenic Substrate—The Influence of Tip-to-Tissue Angulation and Irrigation Flow on Signal Quality." Journal of Vascular Diseases 1, no. 1 (2022): 3–12. http://dx.doi.org/10.3390/jvd1010002.

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Background: The use of mini electrodes with a small surface and narrow electrode-to-electrode spacing is believed to lead to a higher electrical resolution. Until now, the effects of tip-to-tissue contact, angulation, and irrigation on signal quality and morphology are unknown. Methods: The beating heart of an open-chest pig was examined while controlling the angulation and contact between the catheter tip and myocardial tissue, as well as the irrigation of the catheter tip. The mini electrodes were mounted onto commercially available 8 mm non-irrigated and 4 mm irrigated tip catheters. Differ
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Page, Stephen P., and Mehul Dhinoja. "SmartTouch™ – The Emerging Role of Contact Force Technology in Complex Catheter Ablation." Arrhythmia & Electrophysiology Review 1 (2012): 59. http://dx.doi.org/10.15420/aer.2012.1.59.

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Novel technologies have been developed recently to assess contact between the ablation catheter and the underlying tissue in an attempt to improve safe and effective lesion delivery. The most recently developed technology is the SmartTouch™ catheter which is an open irrigated-tip catheter integrated within the CARTO 3 3D mapping system. In this review we consider the role of contact force technology, evaluate the published data and discuss the potential applications of this novel technology.
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Deubner, N., H. Greiss, E. Akkaya, et al. "Clinical experience with contact-force and flexible-tip ablation catheter designs." Journal of Interventional Cardiac Electrophysiology 47, no. 1 (2016): 75–82. http://dx.doi.org/10.1007/s10840-016-0128-3.

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Karkowski, Grzegorz, Marcin Kuniewicz, Andrzej Ząbek, et al. "Contact Force-Sensing versus Standard Catheters in Non-Fluoroscopic Radiofrequency Catheter Ablation of Idiopathic Outflow Tract Ventricular Arrhythmias." Journal of Clinical Medicine 11, no. 3 (2022): 593. http://dx.doi.org/10.3390/jcm11030593.

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Background: Adequate contact between the catheter tip and tissue is important for optimal lesion formation and, in some procedures, it has been associated with improved effectiveness and safety. We evaluated the potential benefits of contact force-sensing (CFS) catheters during non-fluoroscopic radiofrequency catheter ablation (NF-RFCA) of idiopathic ventricular arrhythmias (VAs) originating from outflow tracts (OTs). Methods: A group of 102 patients who underwent NF-RFCA (CARTO, Biosense Webster Inc., Irvine, CA, USA) of VAs from OTs between 2014 to 2018 was retrospectively analyzed. Results:
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Paulsen, Benjamin Alexander, Hannes Schwenke, Jakob Seemann, Peter Schramm, Georg Männel, and Philipp Rostalski. "Towards Test Bench for Aspiration Catheters in Realistic Evaluation Scenarios." Current Directions in Biomedical Engineering 8, no. 2 (2022): 185–88. http://dx.doi.org/10.1515/cdbme-2022-1048.

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Abstract Aspiration catheters play an important role in mechanical thrombectomy in interventional neuroradiology as they provide support for stent retrievers or are increasingly used separately for contact aspiration. To evaluate the performance of different aspiration catheters in terms of suction force, most current studies rely on manual measurement methods or the suction force is not measured close to the aspiration catheter tip. Moreover, there is currently no standardized method that records measurements digitally and with high temporal resolution. To overcome these challenges, we propos
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8

Bunch, T. Jared. "Excessive contact force can overcome irrigated tip catheter benefits during atrial fibrillation ablation." Journal of Cardiovascular Electrophysiology 29, no. 2 (2017): 236–38. http://dx.doi.org/10.1111/jce.13391.

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9

Perna, Francesco, E. Kevin Heist, Stephan B. Danik, Conor D. Barrett, Jeremy N. Ruskin, and Moussa Mansour. "Assessment of Catheter Tip Contact Force Resulting in Cardiac Perforation in Swine Atria Using Force Sensing Technology." Circulation: Arrhythmia and Electrophysiology 4, no. 2 (2011): 218–24. http://dx.doi.org/10.1161/circep.110.959429.

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10

Kluzik, Anna, Hanna Tomczak, Marek Nowicki, et al. "Atomic force microscopy and scanning electron microscopy as alternative methods of early identification of pathogens causing catheter-related bloodstream infections of patients in ICU." Postępy Higieny i Medycyny Doświadczalnej 76, no. 1 (2022): 157–64. http://dx.doi.org/10.2478/ahem-2022-0010.

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Abstract Introduction Vascular catheters are an indispensable element of the therapy of patients in intensive care. Their use is associated with the possibility of complications, including infectious. According to various sources, the incidence of catheter-related bloodstream infections (CRBSIs) ranges from 0.1 to 22.7 per 1,000 catheter days. Materials and Methods The central venous catheter tip culture samples were collected from 24 patients with suspected catheter-related bloodstream infection, from three intensive care units (ICUs). The results of microscopic examinations: atomic force mic
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Cercenelli, Laura, Barbara Bortolani, and Emanuela Marcelli. "CathROB: A Highly Compact and Versatile Remote Catheter Navigation System." Applied Bionics and Biomechanics 2017 (2017): 1–13. http://dx.doi.org/10.1155/2017/2712453.

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Several remote catheter navigation systems have been developed and are now commercially available. However, these systems typically require specialized catheters or equipment, as well as time-consuming operations for the system set-up. In this paper, we present CathROB, a highly compact and versatile robotic system for remote navigation of standard tip-steerable electrophysiology (EP) catheters. Key features of CathROB include an extremely compact design that minimizes encumbrance and time for system set-up in a standard cath lab, a force-sensing mechanism, an intuitive command interface, and
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12

Khoshnam, Mahta, Allan C. Skanes, and Rajni V. Patel. "Modeling and Estimation of Tip Contact Force for Steerable Ablation Catheters." IEEE Transactions on Biomedical Engineering 62, no. 5 (2015): 1404–15. http://dx.doi.org/10.1109/tbme.2015.2389615.

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Yip, Michael C., Jake A. Sganga, and David B. Camarillo. "Autonomous Control of Continuum Robot Manipulators for Complex Cardiac Ablation Tasks." Journal of Medical Robotics Research 02, no. 01 (2017): 1750002. http://dx.doi.org/10.1142/s2424905x17500027.

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Continuum manipulators enable minimally-invasive surgery on the beating heart, but the challenges involved in manually controlling the manipulator’s tip position and contact force with the tissue result in failed procedures and complications. The objective of this work is to achieve autonomous robotic control of a continuum manipulator’s position and force in a beating heart model. We present a model-less hybrid control approach that regulates the tip position/force of manipulators with unknown kinematics/mechanics, under unknown constraints along the manipulator’s body. The algorithms estimat
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Pak, Hui‐Nam, Je‐Wook Park, Song‐Yi Yang, et al. "A mesh‐type flexible tip catheter vs a contact force catheter for catheter ablation of atrial fibrillation: A prospective nonrandomized 1:1 matched study." Journal of Cardiovascular Electrophysiology 31, no. 6 (2020): 1279–88. http://dx.doi.org/10.1111/jce.14484.

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MORI, Koji, Kazuto TAKASHIMA, Shinji KANEMURA, et al. "2F47 Study on catheter and guidewire simulation for intravacular surgery : Estimation for contact force of guidewire tip." Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2014.26 (2014): 519–20. http://dx.doi.org/10.1299/jsmebio.2014.26.519.

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Duytschaever, Mattias, Mark O’Neill, and Martin Martinek. "Increasing the Single-Procedure Success Rate of Pulmonary Vein Isolation." Arrhythmia & Electrophysiology Review 6, no. 4 (2017): 217. http://dx.doi.org/10.15420/aer.2017.38/1.

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To improve the single-procedural success and long-term outcomes of catheter ablation techniques for AF, there is a need for durable, contiguous and transmural lesions encircling the pulmonary veins (PV). Measurement of contact force (CF) between the catheter tip and the target tissue can optimise ablation procedures. A new approach to obtain single-procedure durable PV isolation (PVI) using the latest CF technology combined with the CARTO VISITAG™ Module with Ablation Index (Biosense Webster) has been shown in small studies to almost eliminate recurrence of paroxysmal AF at 1-year follow up an
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17

Zaltieri, Martina, Greta Allegretti, Carlo Massaroni, Emiliano Schena, and Filippo Maria Cauti. "Fiber Bragg Grating Sensors for Millimetric-Scale Temperature Monitoring of Cardiac Tissue Undergoing Radiofrequency Ablation: A Feasibility Assessment." Sensors 20, no. 22 (2020): 6490. http://dx.doi.org/10.3390/s20226490.

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Radiofrequency ablation (RFA) is the most widely used technique for the treatment of cardiac arrhythmias. A variety of factors, such as the electrode tip shape, the force exerted on the tissue by the catheter and the delivered power, combine to determine the temperature distribution, and as consequence, the lesion shape and size. In this context, being able to know the temperature reached in the myocardium during the RFA can be helpful for predicting the lesion dimensions to prevent the occurrence of undesired tissue damage. The catheters used so far in such procedures provide single-point tem
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18

Meshkova, M., and A. Doronin. "Analysis of Complications in 1000 Consecutive Radiofrequency Catheter Ablations of Atrial Fibrillation." Ukrainian Journal of Cardiovascular Surgery, no. 2 (43) (June 18, 2021): 67–71. http://dx.doi.org/10.30702/ujcvs/21.4306/m009067-071/844-037-08.

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Introduction. In patients with drug-refractory symptomatic atrial fibrillation (AF), radiofrequency catheter ablation has become the main treatment option. Despite advances in technology and experience, the incidence of complications for this procedure reported by researchers still varies. In the USA, irrigated catheters are used nearly always, mostly with contact force sensing. We used conventional catheters.
 The aim. To analyze the complications in 1000 consecutive radiofrequency catheter ablations of atrial fibrillation.
 Results and discussion. Non-irrigated 4 mm tip ablation ca
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19

Costea, Alexandru, Laura Goldstein, Sonia Maccioni, Iftekhar Kalsekar, and Rahul Khanna. "Real-world outcomes comparison among adults with atrial fibrillation undergoing catheter ablation with a contact force porous tip catheter versus a second-generation cryoballoon catheter: a retrospective analysis of multihospital US database." BMJ Open 10, no. 8 (2020): e035499. http://dx.doi.org/10.1136/bmjopen-2019-035499.

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ObjectiveTo compare real-world clinical and economic outcomes among atrial fibrillation (AF) patients undergoing cardiac ablation with the contact force-sensing porous tip THERMOCOOL SMARTTOUCH SF (STSF) catheter versus the Arctic Front Advance Cryoballoon (AFA-CB) catheter.DesignRetrospective, observational cohort study.SettingPremier Healthcare Database (PHD), between 1 September 2016 and 30 June 2018.ParticipantsPatients with AF (≥18 years) were included if they had an index ablation procedure performed using the STSF catheter or AFA-CB catheter at a US hospital that consistently provided i
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20

Cha, Hyo-Jeong, Byung-Ju Yi, and Jong Yun Won. "An assembly-type master–slave catheter and guidewire driving system for vascular intervention." Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 231, no. 1 (2016): 69–79. http://dx.doi.org/10.1177/0954411916679328.

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Current vascular intervention inevitably exposes a large amount of X-ray to both an operator and a patient during the procedure. The purpose of this study is to propose a new catheter driving system which assists the operator in aspects of less X-ray exposure and convenient user interface. For this, an assembly-type 4-degree-of-freedom master–slave system was designed and tested to verify the efficiency. First, current vascular intervention procedures are analyzed to develop a new robotic procedure that enables us to use conventional vascular intervention devices such as catheter and guidewire
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Plenge, Tobias, Jan-Hendrik van den Bruck, Jakob Lüker, Arian Sultan, and Daniel Steven. "Porous tip contact force–sensing catheters for pulmonary vein isolation: performance in a clinical routine setting." Journal of Interventional Cardiac Electrophysiology 57, no. 2 (2019): 251–59. http://dx.doi.org/10.1007/s10840-019-00591-2.

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22

Takigawa, Masateru, Masahiko Goya, Junji Yamaguchi, et al. "PO-04-199 CHARACTERISTICS AND SAFETY OF A NOVEL CONTACT-FORCE SENSING IRRIGATED CATHETER WITH A FLEXIBLE TIP WITH LASER-CUT KERFS." Heart Rhythm 20, no. 5 (2023): S572—S573. http://dx.doi.org/10.1016/j.hrthm.2023.03.1215.

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23

Chinitz, Larry A., Daniel P. Melby, Francis E. Marchlinski, et al. "Safety and efficiency of porous-tip contact-force catheter for drug-refractory symptomatic paroxysmal atrial fibrillation ablation: results from the SMART SF trial." EP Europace 20, FI_3 (2017): f392—f400. http://dx.doi.org/10.1093/europace/eux264.

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Nair, Devi G., Martin Martinek, Byron J. Colley, et al. "MP-453081-1 PAROXYSMAL ATRIAL FIBRILLATION ABLATION WITH THE FIRST FLEXIBLE TIP RADIOFREQUENCY CATHETER INCORPORATING CONTACT FORCE SENSING: TACTIFLEX AF IDE TRIAL RESULTS." Heart Rhythm 20, no. 5 (2023): S126. http://dx.doi.org/10.1016/j.hrthm.2023.03.459.

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OKUMURA, YASUO, SUSAN B. JOHNSON, T. JARED BUNCH, BENHUR D. HENZ, CHRISTINE J. O'BRIEN, and DOUGLAS L. PACKER. "A Systematical Analysis ofIn VivoContact Forces on Virtual Catheter Tip/Tissue Surface Contact during Cardiac Mapping and Intervention." Journal of Cardiovascular Electrophysiology 19, no. 6 (2008): 632–40. http://dx.doi.org/10.1111/j.1540-8167.2008.01135.x.

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Maurer, Tilman, Laura Rottner, Hisaki Makimoto, et al. "The best of two worlds? Pulmonary vein isolation using a novel radiofrequency ablation catheter incorporating contact force sensing technology and 56-hole porous tip irrigation." Clinical Research in Cardiology 107, no. 11 (2018): 1003–12. http://dx.doi.org/10.1007/s00392-018-1270-y.

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Anjo, Naofumi, Shiro Nakahara, Yasuo Okumura, et al. "Impact of catheter tip-tissue contact on three-dimensional left atrial geometries: Relationship between the external structures and anatomic distortion of 3D fast anatomical mapping and high contact force guided images." International Journal of Cardiology 222 (November 2016): 202–8. http://dx.doi.org/10.1016/j.ijcard.2016.07.186.

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Fichtner, Stephanie, Tilko Reents, Sonia Ammar, et al. "Pulmonary vein isolation using new technologies to improve ablation lesion formation: Initial results comparing enhanced catheter tip irrigation (Surround Flow®) with contact force measurement (Smarttouch®)." Indian Pacing and Electrophysiology Journal 15, no. 3 (2015): 152–57. http://dx.doi.org/10.1016/j.ipej.2015.07.004.

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Shuang, Tian, Lingcong Kong, Fuyu Cheng, and Xinhua Wang. "Prevalence, Predictors and Mechanisms of Steam Pops in Ablation Index-Guided High-Power Pulmonary Vein Isolation." Journal of Cardiovascular Development and Disease 9, no. 12 (2022): 441. http://dx.doi.org/10.3390/jcdd9120441.

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Despite the good cooling effect of the contact-force porous catheter, the risk of steam pops (SP) remains one of the major concerns in high-power circumferential pulmonary vein isolation (CPVI). This study aimed to investigate the prevalence, predictors and possible mechanisms of SPs in CPVI. Patients experiencing SPs in de novo high-power CPVI were 1:3 matched by non-SP patients with gender, age (±5 years) and left atrial diameter (LAD) (±5 mm) to compare the ablation parameters of SP and non-SP lesions. Catheter tip displacement (Tipdisp) was compared between “edge-of-ridge” and “PV-side-of-
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Masnok, Kriengsak, and Nobuo Watanabe. "Relationship of Catheter Contact Angle and Contact Force with Contact Area on the Surface of Heart Muscle Tissue in Cardiac Catheter Ablation." Cardiovascular Engineering and Technology 12, no. 4 (2021): 407–17. http://dx.doi.org/10.1007/s13239-021-00529-8.

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Abstract Purpose The aims of this study were to develop an experimental procedure for setting the catheter angle with respect to the surface of the heart muscle and the catheter contact force and to investigate the catheter contact area on the heart muscle as a function of catheter contact angle and force. Methods Visualization tests were performed for 5 contact angles (0°, 30°, 45°, 60°, and 90°) and 8 contact forces (2, 4, 6, 10, 15, 20, 30, and 40 gf). Each experiment was repeated 6 times with 2 different commercially available catheter tips. Results The morphology of the contact area was c
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Cheng, Guo Dong, and Xiao Jing Yang. "Nano-Contact Force Calculation Method of Different Tip Radius of Curvature and the Specimen Surface of AFM." Applied Mechanics and Materials 723 (January 2015): 952–57. http://dx.doi.org/10.4028/www.scientific.net/amm.723.952.

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Atomic Force Microscope (AFM) works by the force between the probe tip and specimen surface. The nanocontact force between the probe tip and specimen surface has an important influence on the detection surface. Base on the analysis of the working principle of the AFM and nanocontact force calculation model, according to Hamaker assumptions, using continuum method established the theoretical contact force model of the AFM tip. the contact force calculation methods of contact pressure in process has been obtained. The variation of the force between the probe tip and specimen surface has been fou
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Yaeger, Kurt, Annabelle Iserson, Paul Singh, et al. "A technical comparison of thrombectomy vacuum aspiration systems." Journal of NeuroInterventional Surgery 12, no. 1 (2019): 72–76. http://dx.doi.org/10.1136/neurintsurg-2019-014929.

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IntroductionImproved functional outcomes after mechanical thrombectomy for emergent large vessel occlusion depend on expedient reperfusion after clinical presentation. Device technology has improved substantially over the years, and several commercial options exist for both large-bore aspiration catheters and suction pump systems.ObjectiveTo compare various vacuum pumps and examine the aspiration forces they generate as well as the force of catheter tip detachment from an artificial thrombus.MethodsUsing an artificial thrombus made from polyvinyl alcohol gel, we tested various mechanical chara
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Lally, Frank, Mitra Soorani, Timothy Woo, et al. "In vitro experiments of cerebral blood flow during aspiration thrombectomy: potential effects on cerebral perfusion pressure and collateral flow." Journal of NeuroInterventional Surgery 8, no. 9 (2015): 969–72. http://dx.doi.org/10.1136/neurintsurg-2015-011909.

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BackgroundMechanical thrombectomy with stent retriever devices is associated with significantly better outcomes than thrombolysis alone in the treatment of acute ischemic stroke. Thrombus aspiration achieves high patency rates, but clinical outcomes are variable. The aim of this study was to examine the effect of different suction conditions on perfusate flow during aspiration thrombectomy.MethodsA computational fluid dynamics model of an aspiration device within a patent and occluded blood vessel was used to simulate flow characteristics using fluid flow solver software. A physical particulat
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Natale, Andrea, Vivek Y. Reddy, George Monir, et al. "Paroxysmal AF Catheter Ablation With a Contact Force Sensing Catheter." Journal of the American College of Cardiology 64, no. 7 (2014): 647–56. http://dx.doi.org/10.1016/j.jacc.2014.04.072.

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Froehler, Michael T. "Comparison of Vacuum Pressures and Forces Generated by Different Catheters and Pumps for Aspiration Thrombectomy in Acute Ischemic Stroke." Interventional Neurology 6, no. 3-4 (2017): 199–206. http://dx.doi.org/10.1159/000475478.

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Background: Direct aspiration thrombectomy is an increasingly utilized technique in endovascular stroke treatment that relies on vacuum and suction force to remove the clot. This report assesses the pressures and forces generated by different catheters and pumps. Methods: Vacuum pressures were measured using a vacuum gauge for several catheters (Stryker Catalyst6, Penumbra Ace 064, Medtronic Arc 061, and Penumbra 041) and pumps (Penumbra pump, 60-mL syringe, and the ASPIRE device). Suction forces were calculated based on pressure and catheter tip size (force = area × pressure). Vacuum pressure
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Bessière, Francis, Christopher Zikry, Lena Rivard, Katia Dyrda, and Paul Khairy. "Contact force with magnetic-guided catheter ablation." EP Europace 20, suppl_2 (2018): ii1—ii4. http://dx.doi.org/10.1093/europace/euy006.

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Sweetman, Adam, Nicolas Goubet, Ioannis Lekkas, Marie Paule Pileni, and Philip Moriarty. "Nano-contact microscopy of supracrystals." Beilstein Journal of Nanotechnology 6 (May 29, 2015): 1229–36. http://dx.doi.org/10.3762/bjnano.6.126.

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Background: Highly ordered three-dimensional colloidal crystals (supracrystals) comprised of 7.4 nm diameter Au nanocrystals (with a 5% size dispersion) have been imaged and analysed using a combination of scanning tunnelling microscopy and dynamic force microscopy. Results: By exploring the evolution of both the force and tunnel current with respect to tip–sample separation, we arrive at the surprising finding that single nanocrystal resolution is readily obtained in tunnelling microscopy images acquired more than 1 nm into the repulsive (i.e., positive force) regime of the probe–nanocrystal
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Beltrán, F. J. Espinoza, J. Muñoz-Saldaña, D. Torres-Torres, R. Torres-Martínez, and G. A. Schneider. "Atomic force microscopy cantilever simulation by finite element methods for quantitative atomic force acoustic microscopy measurements." Journal of Materials Research 21, no. 12 (2006): 3072–79. http://dx.doi.org/10.1557/jmr.2006.0379.

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Measurements of vibrational spectra of atomic force microscopy (AFM) microprobes in contact with a sample allow a good correlation between resonance frequencies shifts and the effective elastic modulus of the tip-sample system. In this work we use finite element methods for modeling the AFM microprobe vibration considering actual features of the cantilever geometry. This allowed us to predict the behavior of the cantilevers in contact with any sample for a wide range of effective tip-sample stiffness. Experimental spectra for glass and chromium were well reproduced for the numerical model, and
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Dong, Mei, Mei Li, and Yan Zhang. "The Effect of Tip Materials on the Nanotribology with Atomic Force Microscope Technique." Applied Mechanics and Materials 723 (January 2015): 763–68. http://dx.doi.org/10.4028/www.scientific.net/amm.723.763.

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The effect of tip materials on the friction properties of silicon substrate was investigated by using atomic force microcopy (AFM). The roughness of the silicon wafer surface was characterized with silicon tip at tapping mode, and then the relationship between the friction force and normal force was obtained by silicon tip and silicon nitride tip at contact mode. The experimental results show that when the load exceeds a critical value, the friction coefficient with silicon tip increases from 0.17 to 0.37, which is due to the wear of the silicon tip; the friction coefficient with a hard silico
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Al-Ahmad, Omar, Mouloud Ourak, Johan Vlekken, Eric Lindner, and Emmanuel Vander Poorten. "Three-dimensional catheter tip force sensing using multi-core fiber Bragg gratings." Frontiers in Robotics and AI 10 (March 9, 2023). http://dx.doi.org/10.3389/frobt.2023.1154494.

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Awareness of catheter tip interaction forces is a crucial aspect during cardiac ablation procedures. The most important contact forces are the ones that originate between the catheter tip and the beating cardiac tissue. Clinical studies have shown that effective ablation occurs when contact forces are in the proximity of 0.2 N. Lower contact forces lead to ineffective ablation, while higher contact forces may result in complications such as cardiac perforation. Accurate and high resolution force sensing is therefore indispensable in such critical situations. Accordingly, this work presents the
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Blumfield, Amit, Jay Chudow, John D. Fisher, Luigi DiBiase, Kevin J. Ferrick, and andrew krumerman. "Abstract 15612: Force, Power, and Temperature Settings in Slow Pathway Modification Utilizing an Irrigated Force Sensing Ablation Catheter." Circulation 142, Suppl_3 (2020). http://dx.doi.org/10.1161/circ.142.suppl_3.15612.

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Introduction: Atrioventricular node reentry tachycardia (AVNRT) ablation is typically performed with solid tip catheters set to temperature control (TC) mode. Radiofrequency (RF) output, tip temperature (T), and junctional rhythm response (JRR) during RF application have been well defined. JRR in an intermittent burst, sinus-junction-junction, or sinus-junction-sinus pattern is associated with successful modification of the AV nodal slow pathway (SP). Irrigated force-sensing catheters (IFSC) are often utilized for mapping and ablation of the SP. Despite this, parameters for IFSC used in TC mod
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Gorantla, A., M. Alsaiqali, S. Sivakumar, et al. "Effectiveness of various radiofrequency ablation catheters in the treatment of typical atrial flutter." European Heart Journal 43, Supplement_2 (2022). http://dx.doi.org/10.1093/eurheartj/ehac544.458.

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Abstract Introduction Although ablation of typical atrial flutter (AFL) can be easily achieved with radiofrequency energy (RF), there are no studies that compare effectiveness of different ablation catheters. Our study aimed to compare the effectiveness of various types of ablation catheters in the treatment of AFL. Methods We analysed patients with AFL who underwent RF ablation by a single operator at our institution. Successful ablation was evidenced by presence of bidirectional conduction block (trans-isthmus conduction time ≥130 ms, or doubling of baseline conduction time, or presence of d
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Petras, A., M. Echeverria Ferrero, M. Leoni, J. M. Guerra, J. Jansson, and L. Gerardo-Giorda. "P2431Stay on the safe side: in-silico assessment of ablation protocols to prevent steam pops during radiofrequency ablation." European Heart Journal 40, Supplement_1 (2019). http://dx.doi.org/10.1093/eurheartj/ehz748.0764.

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Abstract Background Steam pops (SP) are among the most serious complications of radiofrequency ablation (RFA) due to its potential to cause myocardial tear or tamponade. SP occur when the tissue overheats, causing its water content to transform into steam and explode. Ablation parameters are critical in order to obtain an optimal lesion size while avoiding the occurrence of SP. However, the interaction between ablation settings and the physical parameters that predispose to SP occurrence during irrigated RFA are not fully understood. Purpose To characterize regularly used ablation protocols by
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Nair, D., M. Martinek, J. Colley, et al. "Acute results of a novel flexible tip radiofrequency catheter incorporating contact force sensing." EP Europace 24, Supplement_1 (2022). http://dx.doi.org/10.1093/europace/euac053.077.

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Abstract Funding Acknowledgements Type of funding sources: Private company. Main funding source(s): Abbott Background Catheter ablation is an established therapy for paroxysmal atrial fibrillation (PAF). The TactiFlex Ablation Catheter, Sensor-Enabled (TactiFlex SE) is a next-generation radiofrequency ablation catheter incorporating highly accurate fiber optics-based contact force sensing technology with a flexible, laser-cut tip. This is the first report of results from the TactiFlex IDE clinical study. Purpose To demonstrate that ablation with TactiFlex SE is safe and effective for the treat
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Alfalahi, Hessa, Federico Renda, Conor Messer, and Cesare Stefanini. "Exploiting the instability of eccentric tube robots for distal force control in minimally invasive cardiac ablation." Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science, May 18, 2021, 095440622110075. http://dx.doi.org/10.1177/09544062211007524.

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While the dilemma of motion tracking and force control in beating-heart surgery is previously addressed using active control architectures and rigid robotic actuators, this work leverages the highly controllable mechanical properties of concentric tube robots for intelligent, design-based force control in minimally invasive cardiac ablation. Briefly, cardiac ablation is the conventional procedure for treating arrhythmia patients, by which exposing the diseased cardiac tissue to Radio-Frequency (RF) energy restores the normal heart rhythm. Yet, the procedure suffers low success rate due to the
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Ramanna, H., J. L. Lloret, F. Zahwe, et al. "P981Comparison of automark utilization and lesion metric target during paroxysmal atrial fibrillation ablation with a contact force-sensing ablation catheter: European and U.S. multicenter Experiences." EP Europace 22, Supplement_1 (2020). http://dx.doi.org/10.1093/europace/euaa162.004.

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Abstract Background Accurate delivery of transmural lesion is associated with improved durability of pulmonary vein isolation and reduced reconduction. Lesion quality depends on multiple parameters such as radiofrequency power, tissue-catheter contact, duration of energy application, and catheter tip temperature. Consequently, energy delivery parameters vary based on individual operators’ preferences and procedural needs. Purpose To characterize and compare the utilization of automated lesion marking feature and lesion delivery parameters used during paroxysmal atrial fibrillation ablation per
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Wintgens, Lisette I. S., Martijn N. Klaver, Moniek Maarse, et al. "Efficacy and safety of the GOLD FORCE multicentre randomized clinical trial: multielectrode phased radiofrequency vs. irrigated radiofrequency single-tip catheter with contact force ablation for treatment of symptomatic paroxysmal atrial fibrillation." EP Europace, July 19, 2021. http://dx.doi.org/10.1093/europace/euab168.

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Abstract Aims Pulmonary vein isolation (PVI) for atrial fibrillation (AF) has become increasingly safe and effective with the evolution of single-tip ablation catheters aided by contact force sensing (ST-CF) and single-shot devices such as the second-generation pulmonary vein ablation catheter (PVAC) Gold multi-electrode array. The multicentre randomized GOLD FORCE trial was conducted to evaluate non-inferiority of safety and efficacy of PVAC Gold PVI compared to ST-CF ablation for paroxysmal AF. Methods and results The primary efficacy endpoint documented AF recurrence ≥30 s was assessed by t
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Alken, Fares-Alexander, Katharina Scherschel, Ann-Kathrin Kahle, Mustafa Masjedi, and Christian Meyer. "Combined contact force and local impedance dynamics during repeat atrial fibrillation catheter ablation." Frontiers in Physiology 13 (October 13, 2022). http://dx.doi.org/10.3389/fphys.2022.1001719.

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Background: Optimal lesion formation during catheter-based radiofrequency current (RFC) ablation depends on electro-mechanical tip-tissue coupling measurable via contact force (CF) and local impedance (LI) monitoring. We aimed to investigate CF and LI dynamics in patients with previous atrial fibrillation (AF) ablation who frequently present with heterogenous arrhythmia substrate.Methods: Data from consecutive patients presenting for repeat AF or atrial tachycardia ablation using a novel open-irrigated single-tip ablation catheter were studied. RFC applications were investigated regarding CF,
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Sairaku, Akinori, Yukiko Nakano, Kazuyoshi Suenari, and Yasuki Kihara. "Abstract 15618: Anatomy Does Matter: The Relationship Between Catheter-Tissue Contact Force and Anatomical Variations of Left Atrium." Circulation 132, suppl_3 (2015). http://dx.doi.org/10.1161/circ.132.suppl_3.15618.

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Background: Adequate catheter-to-myocardial contact force (CF) and catheter stability are important to create transmural lesions during catheter ablation of atrial fibrillation (AF). It is known that there are anatomical variations in left atrium (LA) and it is related to the outcome after the ablation. We tested any relationship between the CF and LA anatomical variations. Methods: Consecutive patients undergoing radiofrequency-based extensive encircling pulmonary vein (PV) isolation for the treatment of paroxysmal AF were dichotomized according to the LA anatomical variations; patients who h
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van de Sande, Werner W. P. J., Awaz Ali, and Giuseppe Radaelli. "Design and Evaluation of a Passive Constant Force Mechanism for a Cardiac Ablation Catheter." Journal of Medical Devices 15, no. 2 (2020). http://dx.doi.org/10.1115/1.4048911.

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Abstract Contact force management has been proven to have a positive effect on the outcome of cardiac ablation procedures. However, no method exists that allows maintaining a constant contact force within a required and effective range. This work aims to develop and evaluate such a constant force mechanism for use in an ablation catheter. A passive constant force mechanism was designed based on a tape loop. The tape loop consists of two tapered springs that work in parallel. A finite element analysis was carried out to verify the behavior and performance of the design. A design based on requir
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