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1

Wang, Hong-Zhan, and Richard D. Veenstra. "Monovalent Ion Selectivity Sequences of the Rat Connexin43 Gap Junction Channel." Journal of General Physiology 109, no. 4 (1997): 491–507. http://dx.doi.org/10.1085/jgp.109.4.491.

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The relative permeability sequences of the rat connexin 43 (rCx43) gap junction channel to seven cations and chloride were examined by double whole cell patch clamp recording of single gap junction channel currents in rCx43 transfected neuroblastoma 2A (N2A) cell pairs. The measured maximal single channel slope conductances (γj, in pS) of the junctional current-voltage relationships in 115 mM XCl were RbCl (103) ≥ CsCl (102) > KCl (97) > NaCl (79) ≥ LiCl (78) > TMACl (65) > TEACl (53) and for 115 mM KY were KBr (105) > KCl (97) > Kacetate (77) >
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2

Tsunenari, T., Y. Hayashi, M. Orita, T. Kurahashi, A. Kaneko, and T. Mori. "A quinine-activated cationic conductance in vertebrate taste receptor cells." Journal of General Physiology 108, no. 6 (1996): 515–23. http://dx.doi.org/10.1085/jgp.108.6.515.

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The chincona alkaloid quinine is known to be a bitter tasting substance for various vertebrates. We examined the effects of quinine on isolated taste receptor cells from the bullfrog (Rana catesbeiana). Membrane currents were recorded by whole-cell recording, while quinine hydrochloride was applied extracellularly from a puffer pipette. At the resting potential (-77 +/- 9 mV, mean +/- SD, n = 49 cells), taste cells generated inward currents in response to quinine stimulation (> 1 mM), indicating a depolarizing response in the taste cells. Two types of current responses were observed; a
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3

Tzan, C. J., J. R. Berg, and S. A. Lewis. "Modification of epithelial permeability by cationic polypeptides." American Journal of Physiology-Cell Physiology 265, no. 6 (1993): C1637—C1647. http://dx.doi.org/10.1152/ajpcell.1993.265.6.c1637.

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It has been demonstrated that protamine sulfate (PS; a cationic polypeptide composed of 70% arginine) increases the apical membrane conductance of the mammalian urinary bladder. In this report, synthetic cationic polypeptides (CpP; e.g., polyarginine) were used to determine whether the response of the bladder to PS was due to its cationic nature (i.e., its arginine content). We demonstrate that CpP induce a large increase in the cation and anion conductance of the apical membrane of the rabbit urinary bladder epithelium. The modulation of the membrane conductance by CpP is dependent upon a num
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4

Tzan, C. J., J. R. Berg, and S. A. Lewis. "Mammalian urinary bladder permeability is altered by cationic proteins: modulation by divalent cations." American Journal of Physiology-Cell Physiology 267, no. 4 (1994): C1013—C1026. http://dx.doi.org/10.1152/ajpcell.1994.267.4.c1013.

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It was previously demonstrated that protamine sulfate (PS, a cationic polypeptide) as well as synthetic cationic polypeptides (CpP, e.g., polylysine and polyarginine) caused an increase in the apical membrane conductance of the mammalian urinary bladder epithelium that was voltage dependent. The membrane conductance induced by these CpP was mediated by a saturable binding site and was partially blocked by CpP (self-inhibition). The PS-induced membrane conductance can be modified by polyvalent cations at three sites. The first site was to competitively inhibit the interaction of PS with an apic
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5

Fologea, Daniel, Eric Krueger, Steve Rossland, Sheenah Bryant, Wylie Foss, and Tyler Clark. "Cationic Polymers Inhibit the Conductance of Lysenin Channels." Scientific World Journal 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/316758.

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The pore-forming toxin lysenin self-assembles large and stable conductance channels in natural and artificial lipid membranes. The lysenin channels exhibit unique regulation capabilities, which open unexplored possibilities to control the transport of ions and molecules through artificial and natural lipid membranes. Our investigations demonstrate that the positively charged polymers polyethyleneimine and chitosan inhibit the conducting properties of lysenin channels inserted into planar lipid membranes. The preservation of the inhibitory effect following addition of charged polymers on either
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6

Zholos, A. V., and T. B. Bolton. "Effects of protons on muscarinic receptor cationic current in single visceral smooth muscle cells." American Journal of Physiology-Gastrointestinal and Liver Physiology 272, no. 2 (1997): G215—G223. http://dx.doi.org/10.1152/ajpgi.1997.272.2.g215.

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Effects of extracellular protons on muscarinic receptor-evoked cationic current (Icat) in single guinea pig ileal smooth muscle cells were studied by use of patch-clamp techniques: intracellular pH and pCa were buffered to 7.4 and 7.0, respectively, symmetrical 124 mM Cs+ solutions were used, and divalent cations were removed from the bathing solution. Increasing extracellular pH (pHo) from 7.4 to 8.4 caused a 16-mV parallel negative shift of the activation curve for Icat evoked by guanosine 5'-O-(3-thiotriphosphate) (GTPgammaS) with an increase in the maximal conductance and slowed Icat relax
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7

Kleine, T. J., A. Gladfelter, P. N. Lewis, and S. A. Lewis. "Histone-induced damage of a mammalian epithelium: the conductive effect." American Journal of Physiology-Cell Physiology 268, no. 5 (1995): C1114—C1125. http://dx.doi.org/10.1152/ajpcell.1995.268.5.c1114.

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Human semen has been reported to be cytotoxic to rat descending colon by a mechanism involving polyamines (cationic molecules) and collagenase. In this study, we report that histones, cationic proteins found in human semen, can contribute to semen's cytotoxicity. Histones H1, H4, and H5, when added to the mucosal side of rabbit urinary bladder epithelium, were found to alter the transepithelial conductance (Gt) in a voltage-sensitive manner. When the cell interior was negative, the conductance rapidly increased and plateaued. When the cell interior was positive, the induced conductance decreas
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8

Queiroga, Claudiene M. de, Geovani S. de Lima, Rafaela A. F. Torres, Francisco J. da S. Paiva, Lauriane A. dos A. Soares, and Hans R. Gheyi. "Formation of guava seedlings under irrigation with water of different cationic natures and salicylic acid." Revista Caatinga 36, no. 3 (2023): 650–62. http://dx.doi.org/10.1590/1983-21252023v36n318rc.

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ABSTRACT The objective of this study was to evaluate gas exchange, biomass, and quality of guava seedlings as a function of the cationic nature of the water used in irrigation and foliar application of salicylic acid. The experiment was carried out in a greenhouse in Pombal, PB, Brazil, using a randomized block design, in a 6 × 4 factorial scheme with six cationic compositions of irrigation water [S1 - Control (supply water); S2 - Na+; S3 - Ca2+; S4 - Na++Ca2+; S5 - Mg2+, and S6 - Na++Ca2++Mg2+], associated with four concentrations of salicylic acid (0, 1.3, 2.6, and 3.9 mM), with 3 replicates
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9

Dobosh, A. Yu, I. A. Sokolov, and N. N. Khimich. "Mixed-Alkali Effect in Glasses of Different Classes in the Framework of a Microinhomogeneous-Glass-Structure Model." Èlektrohimiâ 60, no. 6 (2024): 415–29. http://dx.doi.org/10.31857/s0424857024060044.

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By example of the silicate glasses with the compositions (33.3 – x) Li2O · xNa2O · 66.7SiO2 and (33.3 – x) K2O · xNa2O · 66.7SiO2 with purely cationic conductance and chalcogenide glasses (Ag–Cu)0.33AsSe1.5 and (Ag–Cu)0.61AsSe1.5 with mixed ionic-electronic conductance, consideration has been given to the describing of the mixed-alkali effect in bimetallic glasses in the framework of a microinhomogeneous-glassstructure model using additive schemes involving concentration dependences of conductivity of monometallic glasses with the monovalent metal content equal to that in the mixed glass. A sa
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10

Lee, H. K., C. W. Shuttleworth, and K. M. Sanders. "Tachykinins activate nonselective cation currents in canine colonic myocytes." American Journal of Physiology-Cell Physiology 269, no. 6 (1995): C1394—C1401. http://dx.doi.org/10.1152/ajpcell.1995.269.6.c1394.

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The mechanism of tachykinin-induced excitation was studied in isolated colonic muscle cells and intact muscle strips. In whole cell voltage-clamp studies performed at 33 degrees C, neurokinin A (NKA) and substance P (SP) reduced L-type Ca2+ current. NKA and SP activated a cationic current that reversed near 0 mV. This current (INKA or ISP, respectively) had properties similar to the acetylcholine (ACh)-activated nonselective cation conductance (IACh), activated by muscarinic stimulation in other gastrointestinal smooth muscle cells. INKA and ISP were decreased when external Na+ was reduced. In
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11

Jin, Nan Ge, Sang Don Koh, and Kenton M. Sanders. "Caffeine inhibits nonselective cationic currents in interstitial cells of Cajal from the murine jejunum." American Journal of Physiology-Cell Physiology 297, no. 4 (2009): C971—C978. http://dx.doi.org/10.1152/ajpcell.00155.2009.

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Interstitial cells of Cajal (ICC) discharge unitary potentials in gastrointestinal muscles that constitute the basis for pacemaker activity. Caffeine has been used to block unitary potentials, but the ionic conductance responsible for unitary potentials is controversial. We investigated currents in cultured ICC from murine jejunum that may underlie unitary potentials and studied the effects of caffeine. Networks of ICC generated slow wave events under current clamp, and these events were blocked by caffeine in a concentration-dependent manner. Single ICC generated spontaneous transient inward
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12

Yadav, Ram Nath Prasad. "Synthesis, characterisation and reactions of cationic complexes of Arylantimony (III) chlorides ArnSbCl3-n with perchlorate and tetrafluoroborate anions." International Journal of Applied Sciences and Biotechnology 1, no. 2 (2013): 42–48. http://dx.doi.org/10.3126/ijasbt.v1i2.8204.

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Several hitherto unreported cationic complexes of the general formula [Ar2SbL][Y] and [ArSbL2][Y]2 [ Where, Ar = C6H5, L = α-Picoline, Pyridine, Ph3AsO, hexamethyl phosphoramide (HMPA), thiourea (TU) and Y = ClO4− BF4− ] have been synthesized and characterized by solid state IR, 1H NMR, elemental analysis, conductance and molecular weight measurements. The physico-chemical data, cations [Ar2SbL]+1 and[ArSbL2]+2 are assigned a pyramidal structure.DOI: http://dx.doi.org/10.3126/ijasbt.v1i2.8204 Int J Appl Sci Biotechnol, Vol. 1(2): 42-49
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13

Oliet, S. H., and C. W. Bourque. "Steady-state osmotic modulation of cationic conductance in neurons of rat supraoptic nucleus." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 265, no. 6 (1993): R1475—R1479. http://dx.doi.org/10.1152/ajpregu.1993.265.6.r1475.

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Whole cell patch-clamp recordings were obtained from isolated rat supraoptic nucleus magnocellular neurosecretory cells (MNCs). Under current clamping, hyperosmolality produced by the addition of 10-30 mM mannitol depolarized each of 25 cells tested. In contrast, reducing fluid osmolality from 295 to 265 mosmol/kgH2O had the reverse effect, hyperpolarizing 18 of 21 MNCs. Voltage-clamp recordings in 43 cells revealed that the effects of hypo- and hyperosmolality, respectively, were caused by decreases and increases in a nonselective cation conductance reversing near -41 mV. Current-voltage anal
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14

Lunko, Olesia, Oleksii Lunko, and J. Kevin Foskett. "BPS2025 - Kinetic modeling of nuclear large-conductance cationic channels." Biophysical Journal 124, no. 3 (2025): 130a—131a. https://doi.org/10.1016/j.bpj.2024.11.736.

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15

Smith, J. S., T. Imagawa, J. Ma, M. Fill, K. P. Campbell, and R. Coronado. "Purified ryanodine receptor from rabbit skeletal muscle is the calcium-release channel of sarcoplasmic reticulum." Journal of General Physiology 92, no. 1 (1988): 1–26. http://dx.doi.org/10.1085/jgp.92.1.1.

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The ryanodine receptor of rabbit skeletal muscle sarcoplasmic reticulum was purified as a single 450,000-dalton polypeptide from CHAPS-solubilized triads using immunoaffinity chromatography. The purified receptor had a [3H]ryanodine-binding capacity (Bmax) of 490 pmol/mg and a binding affinity (Kd) of 7.0 nM. Using planar bilayer recording techniques, we show that the purified receptor forms cationic channels selective for divalent ions. Ryanodine receptor channels were identical to the Ca-release channels described in native sarcoplasmic reticulum using the same techniques. In the present wor
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16

Palepu, Ramamurthy, and Vincent C. Reinsborough. "Surfactant–cyclodextrin interactions by conductance measurements." Canadian Journal of Chemistry 66, no. 2 (1988): 325–28. http://dx.doi.org/10.1139/v88-056.

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Conductance measurements were used to identify and to obtain association constants for the complexes formed between cyclodextrins (CD) with emphasis on β-cyclodextrin (βCD), and surfactants such as sodium dodecylsulfate (SDS) and tetradecyltrimethyl ammonium bromide. With both anionic and cationic surfactants, αCD forms predominantly a 2:1 CD/surfactant complex while with both βCD and γCD the main species is 1:1. γCD binds much less strongly with surfactants than both αCD and βCD. Cyclodextrins destroy micelles by complexing the surfactant monomers more strongly than they are bound in self-ass
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17

Amarillo, Yimy, Edward Zagha, German Mato, Bernardo Rudy, and Marcela S. Nadal. "The interplay of seven subthreshold conductances controls the resting membrane potential and the oscillatory behavior of thalamocortical neurons." Journal of Neurophysiology 112, no. 2 (2014): 393–410. http://dx.doi.org/10.1152/jn.00647.2013.

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The signaling properties of thalamocortical (TC) neurons depend on the diversity of ion conductance mechanisms that underlie their rich membrane behavior at subthreshold potentials. Using patch-clamp recordings of TC neurons in brain slices from mice and a realistic conductance-based computational model, we characterized seven subthreshold ion currents of TC neurons and quantified their individual contributions to the total steady-state conductance at levels below tonic firing threshold. We then used the TC neuron model to show that the resting membrane potential results from the interplay of
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18

Amarillo, Yimy, Angela I. Tissone, Germán Mato, and Marcela S. Nadal. "Inward rectifier potassium current IKir promotes intrinsic pacemaker activity of thalamocortical neurons." Journal of Neurophysiology 119, no. 6 (2018): 2358–72. http://dx.doi.org/10.1152/jn.00867.2017.

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Slow repetitive burst firing by hyperpolarized thalamocortical (TC) neurons correlates with global slow rhythms (<4 Hz), which are the physiological oscillations during non-rapid eye movement sleep or pathological oscillations during idiopathic epilepsy. The pacemaker activity of TC neurons depends on the expression of several subthreshold conductances, which are modulated in a behaviorally dependent manner. Here we show that upregulation of the small and neglected inward rectifier potassium current IKir induces repetitive burst firing at slow and delta frequency bands. We demonstrate this
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19

Arellano, R. O., R. M. Woodward, and R. Miledi. "A monovalent cationic conductance that is blocked by extracellular divalent cations in Xenopus oocytes." Journal of Physiology 484, no. 3 (1995): 593–604. http://dx.doi.org/10.1113/jphysiol.1995.sp020689.

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20

Kallol, K. Ghosh, and Pandey Alka. "Kinetics of alkaline hydrolysis of hydroxamic acid in mixed micelles of binary surfactant systems." Journal of Indian Chemical Society Vol. 76, Apr 1999 (1999): 191–94. https://doi.org/10.5281/zenodo.5848190.

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School of Studies in Chemistry, Pt. Ravishankar&#39;Shukla University, Raipur-492 010, India <em>Manuscript received 16 March 1998, revised 7 December 1998, accepted 23 December 1998</em> The alkaline hydrolysis of <em>N</em>-phenylbenzohydroxamic acid has been studied in binary combinations of cationic-cationic, cationic-non ionic and anionic-nonionic surfactant systems at 55&ordm;. The experimental results obtained from conductance and kinetic measurements allowed us to achieve significant information about the systems. Addition of cationic surfactant to nonionic surfactant accelerates the r
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21

Kleine, Teri J., Gerald J. Gleich, and Simon A. Lewis. "Eosinophil peroxidase increases membrane permeability in mammalian urinary bladder epithelium." American Journal of Physiology-Cell Physiology 276, no. 3 (1999): C638—C647. http://dx.doi.org/10.1152/ajpcell.1999.276.3.c638.

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Eosinophil peroxidase (EPO), a cationic protein found in eosinophils, has been reported to be cytotoxic independent of its peroxidase activity. This study investigated with electrophysiological methods whether EPO is toxic to mammalian urinary bladder epithelium. Results indicate that EPO, when added to the mucosal solution, increases apical membrane conductance of urinary bladder epithelium only when the apical membrane potential is cell interior negative. The EPO-induced conductance was concentration dependent, with a maximum conductance of 411 μS/cm2 and a Michaelis-Menten constant of 113 n
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22

Wang, Junjie, David George Jackson, and Gerhard Dahl. "Cationic control of Panx1 channel function." American Journal of Physiology-Cell Physiology 315, no. 3 (2018): C279—C289. http://dx.doi.org/10.1152/ajpcell.00303.2017.

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The sequence and predicted membrane topology of pannexin1 (Panx1) places it in the family of gap junction proteins. However, rather than forming gap junction channels, Panx1 forms channels in the nonjunctional membrane. Panx1 operates in two distinct open states, depending on the mode of stimulation. The exclusively voltage-gated channel has a small conductance (&lt;100 pS) and is highly selective for the flux of chloride ions. The Panx1 channel activated by various physiological stimuli or by increased concentrations of extracellular potassium ions has a large conductance (~500 pS, however, w
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23

Khanal, Manoj. "Study of Methyl Orange-Cetyltrimethyl Ammonium Bromide Interaction by Conductivity Method in Methanol-Water Mixed Solvent Media." International Journal of Applied Sciences and Biotechnology 5, no. 2 (2017): 172–79. http://dx.doi.org/10.3126/ijasbt.v5i2.17622.

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The interaction of an anionic dye (Methyl Orange) with cationic surfactant (Cetyltrimethylammonium Bromide, CTAB) in the series of solvent containing variable compositions of methanol-water mixture (10%, 20%, 30% and 40%) was studied at room temperature (31±2oC). Conductivity measurements were done for the investigation of interaction of dyes. The specific conductance of 6.58x10-5 M to 59.22x10-5M surfactant (CTAB) and these surfactants with 1.008x10-3M dye (MO) mixtures were noted at room temperature. A theoretical model was used to calculate conductance ratio from the data of measured specif
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24

Bolívar, Juan J., Dagoberto Tapia, Gabina Arenas, Mauricio Castañón-Arreola, Haydee Torres, and Elvira Galarraga. "A hyperpolarization-activated, cyclic nucleotide-gated, (Ih-like) cationic current and HCN gene expression in renal inner medullary collecting duct cells." American Journal of Physiology-Cell Physiology 294, no. 4 (2008): C893—C906. http://dx.doi.org/10.1152/ajpcell.00616.2006.

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The cation conductancein primary cultures of rat renal inner medullary collecting duct was studied using perforated-patch and conventional whole cell clamp techniques. Hyperpolarizations beyond −60 mV induced a time-dependent inward nonselective cationic current ( Ivti) that resembles the well-known hyperpolarization-activated, cyclic nucleotide-gated Ih and If currents. Ivti showed a half-maximal activation around −102 mV with a slope factor of 25 mV. It had a higher conductance (but, at its reversal potential, not a higher permeability) for K+ than for Na+ ( gK+/ gNa+ = 1.5), was modulated b
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25

Jones, Leslie Sargent, and Darrell V. Lewis. "A calcium-activated, nonselective cationic conductance in Aplysia silent neurons." Brain Research Bulletin 20, no. 5 (1988): 607–9. http://dx.doi.org/10.1016/0361-9230(88)90220-1.

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26

Madrid, Rodolfo, Ricardo Delgado, and Juan Bacigalupo. "Cyclic AMP Cascade Mediates the Inhibitory Odor Response of Isolated Toad Olfactory Receptor Neurons." Journal of Neurophysiology 94, no. 3 (2005): 1781–88. http://dx.doi.org/10.1152/jn.01253.2004.

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Odor stimulation may excite or inhibit olfactory receptor neurons (ORNs). It is well established that the excitatory response involves a cyclic AMP (cAMP) transduction mechanism that activates a nonselective cationic cyclic nucleotide-gated (CNG) conductance, accompanied by the activation of a Ca2+-dependent Cl− conductance, both causing a depolarizing receptor potential. In contrast, odor inhibition is attributed to a hyperpolarizing receptor potential. It has been proposed that a Ca2+-dependent K+ (KCa) conductance plays a key role in odor inhibition, both in toad and rat isolated olfactory
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27

Goraczniak, R. M., T. Duda, A. Sitaramayya, and R. K. Sharma. "Structural and functional characterization of the rod outer segment membrane guanylate cyclase." Biochemical Journal 302, no. 2 (1994): 455–61. http://dx.doi.org/10.1042/bj3020455.

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In the vertebrate photoreceptor cell, rod outer segment (ROS) is the site of visual signal-transduction process, and a pivotal molecule that regulates this process is cyclic GMP. Cyclic GMP controls the cationic conductance into the ROS, and light causes a decrease in the conductance by activating hydrolysis of the cyclic nucleotide. The identity of the granylate cyclase (ROS-GC) that synthesizes this pool of cyclic GMP is unknown. We now report the cloning, expression and functional characterization of a DNA from bovine retina that encodes ROS-GC.
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28

Achard, J. M., J. K. Bubien, D. J. Benos, and D. G. Warnock. "Stretch modulates amiloride sensitivity and cation selectivity of sodium channels in human B lymphocytes." American Journal of Physiology-Cell Physiology 270, no. 1 (1996): C224—C234. http://dx.doi.org/10.1152/ajpcell.1996.270.1.c224.

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Stretch-mediated regulation of amiloride-sensitive Na+ channels was examined in Epstein-Barr virus-transformed human B lymphocytes. Cation conductances were measured using whole cell patch-clamp techniques. Stretch activation, induced by increasing the hydrostatic pressure of the bath solution, immediately and reversibly increased both inward and outward ionic conductances once a threshold of 2-5 mmH2O was reached. Ionic substitutions confirmed that stretch enhanced membrane conductivity for both Na+ and K+. Amiloride (2 microM) completely prevented the response to elevated hydrostatic pressur
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Swandulla, D. "Cationic membrane conductances induced by intracellularly elevated cAMP and Ca2+: measurements with ion-selective microelectrodes." Canadian Journal of Physiology and Pharmacology 65, no. 5 (1987): 898–903. http://dx.doi.org/10.1139/y87-145.

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Adenosine 3′,5′-cyclic monophosphate (cAMP) and CaCl2 were injected by a fast and quantitative pressure injection technique into voltage-clamped, identified Helix neurons. Intracellular elevation of cAMP as well as of Ca2+ activated an inward current (IcAMP and IN). To identify the ionic fluxes during IcAMP and IN changes in [Na+]i, [K+]o, [H+]i, and [Cl−]i were measured with ion-selective microelectrodes (ISMs). Near resting potential, Na+ was the main carrier of IcAMP. K+, and less effectively Ca2+, could substitute for Na+ in carrying IcAMp. H+ and Cl− were excluded as current carriers for
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30

Berg, Jamie R., Christian M. Spilker, and Simon A. Lewis. "Modulation of polymyxin B effects on mammalian urinary bladder." American Journal of Physiology-Renal Physiology 275, no. 2 (1998): F204—F215. http://dx.doi.org/10.1152/ajprenal.1998.275.2.f204.

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This report demonstrates that Ca2+, Mg2+, and protons alter the ability of polymyxin B (PX, a cationic antibiotic used clinically as a bactericidal agent) to increase the apical membrane conductance of the rabbit urinary bladder. Using electrophysiological methods, we determine that these alterations occur by two mechanisms. First, they blocked the PX-induced conductance in a rapid and reversible manner; second, they competed with PX for a membrane binding site. In addition, Ca2+(but not Mg2+or protons) altered the rate at which the induced conductance could be reversed. When solution pH was g
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31

Fedorenko, E. A., O. V. Semenova, and S. M. Marchenko. "Properties of Large-Conductance Cationic Channels in the Neuronal Nuclear Envelope." Neurophysiology 43, no. 3 (2011): 192–94. http://dx.doi.org/10.1007/s11062-011-9202-8.

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32

Schweitzer, Paul, Samuel G. Madamba, and George R. Siggins. "Somatostatin Increases a Voltage-Insensitive K+ Conductance in Rat CA1 Hippocampal Neurons." Journal of Neurophysiology 79, no. 3 (1998): 1230–38. http://dx.doi.org/10.1152/jn.1998.79.3.1230.

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Schweitzer, Paul, Samuel G. Madamba, and George R. Siggins. Somatostatin increases a voltage-insensitive K+ conductance in rat CA1 hippocampal neurons. J. Neurophysiol. 79: 1230–1238, 1998. Somatostatin (SST) is a neuropeptide involved in several central processes. In hippocampus, SST hyperpolarizes CA1 pyramidal neurons and augments the K+ M current ( I M). However, the limited involvement of I M at resting potential in these cells suggests that the peptide also may modulate another channel to hyperpolarize hippocampal pyramidal neurons (HPNs). We studied the effect of SST on noninactivating
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33

I., P. PANDEY. "Effect of Temperature on the Conductance of Oil/Oil Emulsions Stabilised by Cationic and Nonionic Surfactants." Journal of Indian Chemical Society Vol. 65, Mar 1988 (1988): 222–23. https://doi.org/10.5281/zenodo.6077078.

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Department of Chemistry, D. A. V. (P. G.) College, Dehra Dun-248 001 <em>Manuscript received 10 December 1986, revised 23 February 1987, accepted 21 April 1987</em> THE conductance of the oil/water emulsions have been measured by various workers to study the effect of concentration<sup>1</sup> , emulsification time and temperature, phase-volume ratio, temperature<sup>2</sup>, ageing effect<sup>3</sup> etc. A survey of literature reveals that oil/oil emulsions have been investigated to a very limited extent<sup>4</sup>. Hence, it was thought worthwhile to prepare kerosene oil/ethylene glycol an
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34

Bera, Achinta, Ajay Mandal, Keka Ojha, and T. Kumar. "Water Solubilization Capacity and Conductance Behaviors of Anionic and Cationic Microemulsion Systems." Journal of Chemical & Engineering Data 56, no. 12 (2011): 4422–29. http://dx.doi.org/10.1021/je200291v.

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35

Wu, Tony, and Hung-Li Wang. "CCK-8 excites substantia nigra dopaminergic neurons by increasing a cationic conductance." Neuroscience Letters 170, no. 2 (1994): 229–32. http://dx.doi.org/10.1016/0304-3940(94)90325-5.

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36

Hamilton, K. L., and D. C. Eaton. "Single-channel recordings from amiloride-sensitive epithelial sodium channel." American Journal of Physiology-Cell Physiology 249, no. 3 (1985): C200—C207. http://dx.doi.org/10.1152/ajpcell.1985.249.3.c200.

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We report here the first evidence in intact epithelial cells of unit conductance events from an amiloride-sensitive Na+ channel. The events were observed when patch-clamp recordings were made from the apical surface of cultured epithelial kidney cells (A6). The channel characteristics are as follows. Single-channel conductance ranged between 7 and 10 pS (mean = 8.4 +/- 1.3), the current-voltage (I-V) relationship displayed little if any nonlinearity over a range of +/- 80 mV (with respect to the patch pipette), and the channel Na+/K+ selectivity was approximately 3-4:1. Amiloride, a cationic b
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37

Li, Allen H., Hwa-Min Hwang, Peter P. Tan, Tony Wu, and Hung-Li Wang. "Neurotensin Excites Periaqueductal Gray Neurons Projecting to the Rostral Ventromedial Medulla." Journal of Neurophysiology 85, no. 4 (2001): 1479–88. http://dx.doi.org/10.1152/jn.2001.85.4.1479.

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Microinjection of neurotensin into the midbrain periaqueductal gray (PAG) produces a potent and naloxone-insensitive analgesic effect. To test the hypothesis that neurotensin induces the analgesic effect by activating the PAG-rostral ventromedial medulla (RVM) descending antinociceptive pathway, PAG neurons that project to RVM (PAG-RVM) were identified by microinjecting DiIC18, a retrograde tracing dye, into the rat RVM. Subsequently, fluorescently labeled PAG-RVM projection neurons were acutely dissociated and selected for whole cell patch-clamp recordings. During current-clamp recordings, ne
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38

Tissone, Angela Isabel, Varinia Beatriz Vidal, Marcela Silvia Nadal, German Mato, and Yimy Amarillo. "Differential contribution of the subthreshold operating currents IT, Ih, and IKir to the resonance of thalamocortical neurons." Journal of Neurophysiology 126, no. 2 (2021): 561–74. http://dx.doi.org/10.1152/jn.00147.2021.

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Our study expands the repertoire of ionic mechanisms known to be involved in the generation and control of resonance and provides the first experimental proof of previous theoretical predictions on resonance amplification mediated by regenerative hyperpolarizing currents. In thalamocortical neurons, we confirmed that the calcium current IT generates resonance, determined that the large steady conductance of the cationic current Ih curtails resonance, and demonstrated that the inward rectifier potassium current IKir amplifies resonance.
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39

Yang, Bo, Martin Goulet, Richard Boismenu, and Alastair V. Ferguson. "Secretin depolarizes nucleus tractus solitarius neurons through activation of a nonselective cationic conductance." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 286, no. 5 (2004): R927—R934. http://dx.doi.org/10.1152/ajpregu.00600.2003.

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The recent suggestion that secretin may be useful in treating autism and schizophrenia has begun to focus attention on the mechanisms underlying this gut-brain peptide's actions in the central nervous system (CNS). In vitro autoradiographic localization of 125I-secretin binding sites in rat brain shows the highest binding density in the nucleus tractus solitarius (NTS). Recent evidence suggests that intravenous infusion of secretin causes fos activation in NTS, a relay station playing important roles in the central regulation of autonomic functions. In this study, whole cell patch-clamp record
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Hlavac, Nora, Fernanda Guilhaume-Corrêa, and Pamela J. VandeVord. "Mechano-stimulation initiated by extracellular adhesion and cationic conductance pathways influence astrocyte activation." Neuroscience Letters 739 (November 2020): 135405. http://dx.doi.org/10.1016/j.neulet.2020.135405.

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41

Shan, Yuping, Namuna Panday, Yong Myoung, et al. "Scanning Ion Conductance Microscopic Study for Cellular Uptake of Cationic Conjugated Polymer Nanoparticles." Macromolecular Bioscience 16, no. 4 (2016): 599–607. http://dx.doi.org/10.1002/mabi.201500320.

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42

Thieffry, M., J. F. Chich, D. Goldschmidt, and J. P. Henry. "Incorporation in lipid bilayers of a large conductance cationic channel from mitochondrial membranes." EMBO Journal 7, no. 5 (1988): 1449–54. http://dx.doi.org/10.1002/j.1460-2075.1988.tb02962.x.

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43

Lima, Geovani S. de, Hans R. Gheyi, Reginaldo G. Nobre, et al. "Physiological Indices and Growth of Castor Bean Irrigated With Waters of Different Cationic Nature." Journal of Agricultural Science 10, no. 10 (2018): 405. http://dx.doi.org/10.5539/jas.v10n10p405.

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It was proposed, in the present study, to evaluate the gas exchange and the growth of the castor bean cv. BRS Energia due to the isolated or mixed cationic nature of irrigation water. The study was conducted in drainage lysimeters under greenhouse conditions, using an Eutrophic Greyish Argissolo with a sandy-loam texture in the municipality of Campina Grande, Brazil. A randomized block design was used with six cationic composition of irrigation water (S1-control, S2-Na+, S3-Ca2+, S4-Na++Ca2+, S5-K+ and S6-Na++Ca2++Mg2+ with four replicates, each composed of five plants. The plants under the co
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Santa Cruz, Ana, Gülistan Meşe, Laima Valiuniene, Peter R. Brink, Thomas W. White, and Virginijus Valiunas. "Altered conductance and permeability of Cx40 mutations associated with atrial fibrillation." Journal of General Physiology 146, no. 5 (2015): 387–98. http://dx.doi.org/10.1085/jgp.201511475.

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Gap junctions ensure the rapid propagation of the action potential throughout the myocardium. Three mutant forms of connexin40 (Cx40; A96S, M163V, and G38D), the primary component of the atrial gap junction channel, are associated with atrial fibrillation and retain the ability to form functional channels. We determined the biophysical properties of these mutant gap junctions in transiently transfected HeLa and N2A cells. All three mutants showed macroscopic junctional conductances over the range of 0.5 to 40 nS, and voltage dependences comparable to those of wild-type (WT) Cx40. However, the
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Klink, R., and A. Alonso. "Ionic mechanisms for the subthreshold oscillations and differential electroresponsiveness of medial entorhinal cortex layer II neurons." Journal of Neurophysiology 70, no. 1 (1993): 144–57. http://dx.doi.org/10.1152/jn.1993.70.1.144.

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1. Layer II of the medial entorhinal cortex is composed of two electrophysiologically and morphologically distinct types of projection neurons: stellate cells (SCs), which are distinguished by rhythmic subthreshold oscillatory activity, and non-SCs. The ionic mechanisms underlying their differential electroresponsiveness, particularly in the subthreshold range of membrane potentials, were investigated in an "in vitro" slice preparation. 2. In both SCs and non-SCs, the apparent membrane input resistance was markedly voltage dependent, respectively decreasing or increasing at hyperpolarized or s
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46

Van Driessche, W., and D. Erlij. "Activation of K+ conductance in basolateral membrane of toad urinary bladder by oxytocin and cAMP." American Journal of Physiology-Cell Physiology 254, no. 6 (1988): C816—C821. http://dx.doi.org/10.1152/ajpcell.1988.254.6.c816.

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We incubated toad urinary bladders with Na+-free, isotonic K+ solutions on the apical side and increased the cationic conductance of the apical membrane with nystatin (150 U/ml). Under these conditions, the short-circuit current is mostly carried by K+ flowing from mucosa to serosa. Impedance measurements showed that in nystatin-treated preparations, the electrical behavior of the tissue is dominated by the basolateral membrane properties. Oxytocin (0.1 U/ml) produced an increase of the current and the conductance of the basolateral membrane. Both the resting and the oxytocin-stimulated curren
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47

Yang, Bo, and Alastair V. Ferguson. "Orexin-A Depolarizes Nucleus Tractus Solitarius Neurons Through Effects on Nonselective Cationic and K+ Conductances." Journal of Neurophysiology 89, no. 4 (2003): 2167–75. http://dx.doi.org/10.1152/jn.01088.2002.

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The nucleus tractus solitarius (NTS) plays central roles in a number of autonomic functions including cardiovascular control. Orexin (ORX)-A is a 33-amino-acid peptide implicated in the central regulation of energy metabolism, sleep, and the cardiovascular system. Studies demonstrate the presence of ORX-immunoreactive axons and both OX1R (orexin receptor) and OX2R mRNA within NTS. In this study, whole cell patch-clamp recordings were obtained from NTS neurons in rat medullary slices. Current-clamp studies showed that bath application of various concentrations of ORX-A depolarized 90.7% (78 of
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48

Herness, M. Scott, and Xiao-Dong Sun. "Characterization of Chloride Currents and Their Noradrenergic Modulation in Rat Taste Receptor Cells." Journal of Neurophysiology 82, no. 1 (1999): 260–71. http://dx.doi.org/10.1152/jn.1999.82.1.260.

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Taste receptor cells contain a heterogeneous array of voltage-dependent ion conductances that are essential components for the transduction of gustatory stimuli. Although mechanistic roles have been proposed for several cationic conductances, the understanding of anionic currents is rudimentary. This study characterizes biophysical and pharmacological properties of chloride currents in rat posterior taste cells using whole cell patch-clamp recording technique. Taste cells express a heterogeneous array of chloride currents that displayed strong outward rectification, contained both calcium–depe
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Balleza, Daniel, Froylán Gómez-Lagunas, Federico Sánchez, and Carmen Quinto. "A high conductance cationic channel from Phaseolus vulgaris roots incorporated into planar lipid bilayers." Archives of Biochemistry and Biophysics 438, no. 1 (2005): 88–92. http://dx.doi.org/10.1016/j.abb.2005.04.007.

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50

Navarro, Franz E. C., José A. Santos Júnior, Juliana B. Martins, Ruana I. F. Cruz, Manassés M. da Silva, and Salomão de S. Medeiros. "Physiological aspects and production of coriander using nutrient solutions prepared in different brackish waters." Revista Brasileira de Engenharia Agrícola e Ambiental 26, no. 11 (2022): 831–39. http://dx.doi.org/10.1590/1807-1929/agriambi.v26n11p831-839.

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ABSTRACT The analysis of chlorophyll fluorescence is one of many ways to quantify the salt damage to photosynthetic performance and crop production. Thus, the present study aimed to evaluate the photochemical efficiency and production of coriander, cultivar ‘Verdão’, as a function of the electrical conductivity levels of the nutrient solution and the cationic nature. The experimental design was in randomized blocks, in a 4 × 3 factorial scheme, with four replicates. The treatments consisted of four electrical conductivities of the nutrient solutions (ECns = 1.6, 3.2, 4.8, and 6.4 dS m-1) and t
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