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1

Schebesta, Michael, Ching-Ling Lien, Felix B. Engel, and Mark T. Keating. "Transcriptional Profiling of Caudal Fin Regeneration in Zebrafish." Scientific World JOURNAL 6 (2006): 38–54. http://dx.doi.org/10.1100/tsw.2006.326.

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Regeneration of severed limbs in adult animals is restricted to urodele amphibians. Mammals, including humans, have very limited regenerative capabilities and even with proper treatment, only the tips of our digits can grow back. Teleost fish can regenerate amputated fins, the evolutionary ancestors of limbs. To elucidate the principles of limb-fin regeneration, we performed an Affymetrix microarray screen on regenerating caudal fins 12, 24, 48, and 72 h post amputation. Approximately 15,000 zebrafish transcripts were analyzed, identifying 829 transcripts as differentially expressed during reg
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2

Thummel, Ryan, Christopher T. Burket, and David R. Hyde. "Two Different Transgenes to Study Gene Silencing and Re-Expression During Zebrafish Caudal Fin and Retinal Regeneration." Scientific World JOURNAL 6 (2006): 65–81. http://dx.doi.org/10.1100/tsw.2006.328.

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We used the 500-bpXenopusef1-α promoter and the 2-kb zebrafish histone2A.F/Zpromoter to generate several independent transgenic zebrafish lines expressing EGFP. While both promoters drive ubiquitous EGFP expression in early zebrafish development, they are systematically silenced in several adult tissues, including the retina and caudal fin. However, EGFP expression is temporarily renewed in the adult during either caudal fin or retinal regeneration. In the Tg(H2A.F/Z:EGFP)ntline, EGFP is moderately expressed in both the wound epithelium and blastema of the regenerating caudal fin. In the Tg(ef
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3

Nakajima, Wataru, Soya Nakanishi, Ryosuke Hosoya, Toshiaki Uemoto, Shiro Ohgo, and Naoyuki Wada. "Regenerative Polarity of the Fin Ray in Zebrafish Caudal Fin and Related Tissue Formation on the Cut Surface." Journal of Developmental Biology 9, no. 4 (2021): 50. http://dx.doi.org/10.3390/jdb9040050.

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Zebrafish caudal fin rays are used as a model system for regeneration because of their high regenerative ability, but studies on the regeneration polarity of the fin ray are limited. To investigate this regeneration polarity, we made a hole to excise part of the fin ray and analyzed the regeneration process. We confirmed that the fin rays always regenerated from the proximal margin toward the distal margin, as previously reported; however, regeneration-related genes were expressed at both the proximal and distal edges of the hole in the early stage of regeneration, suggesting that the regenera
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4

Hou, Yiran, Hyung Joo Lee, Yujie Chen, et al. "Cellular diversity of the regenerating caudal fin." Science Advances 6, no. 33 (2020): eaba2084. http://dx.doi.org/10.1126/sciadv.aba2084.

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Zebrafish faithfully regenerate their caudal fin after amputation. During this process, both differentiated cells and resident progenitors migrate to the wound site and undergo lineage-restricted, programmed cellular state transitions to populate the new regenerate. Until now, systematic characterizations of cells comprising the new regenerate and molecular definitions of their state transitions have been lacking. We hereby characterize the dynamics of gene regulatory programs during fin regeneration by creating single-cell transcriptome maps of both preinjury and regenerating fin tissues at 1
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Nguyen-Chi, Mai, Béryl Laplace-Builhé, Jana Travnickova, et al. "TNF signaling and macrophages govern fin regeneration in zebrafish larvae." Cell Death & Disease 8, no. 8 (2017): e2979-e2979. http://dx.doi.org/10.1038/cddis.2017.374.

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Abstract Macrophages are essential for appendage regeneration after amputation in regenerative species. The molecular mechanisms through which macrophages orchestrate blastema formation and regeneration are still unclear. Here, we use the genetically tractable and transparent zebrafish larvae to study the functions of polarized macrophage subsets during caudal fin regeneration. After caudal fin amputation, we show an early and transient accumulation of pro-inflammatory macrophages concomitant with the accumulation of non-inflammatory macrophages which, in contrast to pro-inflammatory macrophag
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6

White, J. A., M. B. Boffa, B. Jones, and M. Petkovich. "A zebrafish retinoic acid receptor expressed in the regenerating caudal fin." Development 120, no. 7 (1994): 1861–72. http://dx.doi.org/10.1242/dev.120.7.1861.

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Retinoic acid (RA) is an important signalling molecule in vertebrate pattern formation both in developing and regenerating tissues. The effects of RA are due largely to regulation of gene transcription, mediated by retinoic acid receptors (RAR-alpha, RAR-beta, RAR-gamma) and retinoid X receptors (RXR-alpha, RXR-beta, RXR-gamma). We have been using zebrafish as a model of regeneration to study the role of retinoic acid and its receptors in vertebrate pattern formation. In this report, we describe the molecular cloning and characterization of one of the zebrafish RARs that is the predominant rec
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7

Sarmah, Swapnalee, Courtney Curtis, Jennifer Mahin та ін. "The Glycogen Synthase Kinase-3β Inhibitor LSN 2105786 Promotes Zebrafish Fin Regeneration". Biomedicines 7, № 2 (2019): 30. http://dx.doi.org/10.3390/biomedicines7020030.

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The Wnt pathway has been shown to regulate bone homeostasis and to influence some bone disease states. We utilized a zebrafish model system to study the effects of a synthetic, orally bioavailable glycogen synthase kinase-3β (GSK3β) inhibitor LSN 2105786, which activates Wnt signaling during bone healing and embryogenesis. GSK3β inhibitor treatment was used to phenocopy GSK3β morpholino oligonucleotide (MO) knockdown in zebrafish embryos. Human and zebrafish synthetic mRNA injection were similarly effective at rescue of GSK3β MO knockdown. During caudal fin regeneration, bony rays are the firs
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8

Li, Jing, Wenjun Wen, Shuqiang Zhang, Chune Zhou, Yiyi Feng, and Xiaoyu Li. "The Expression and Function of lincRNA-154324 and the Adjoining Protein-Coding Gene vmp1 in the Caudal Fin Regeneration of Zebrafish." International Journal of Molecular Sciences 23, no. 16 (2022): 8944. http://dx.doi.org/10.3390/ijms23168944.

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Caudal fin regeneration is regulated by a variety of mechanisms, but the role of long non-coding RNA (lncRNA) has rarely been studied. The present study aimed to describe the landscape of lncRNAs during caudal fin regeneration using whole transcriptome sequencing, and then to conduct a functional study on the target lncRNAs using real-time fluorescent quantitative PCR (RT-qPCR), in situ hybridization, and the CRISPR/Cas9 method for lncRNA gene knockout. The results of the transcriptome sequencing showed that a total of 381 lncRNAs were differentially expressed, among which ENSDART00000154324 (
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9

Nurkhasanah, Lia, Farida Hayati, and Rochmy Istikharah. "Zebrafish as a model for the study of wound healing in hyperglycemia." Pharmacy Education 24, no. 3 (2024): 111–15. http://dx.doi.org/10.46542/pe.2024.243.111115.

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Background: For preclinical studies of diabetic wound therapy, zebrafish have many orthologous signalling pathways that play essential roles in wound healing and regeneration. Objectives: This study compares the expression of four essential wound-healing genes and caudal fin regeneration in hyperglycemic zebrafish (Danio rerio) to normal zebrafish. Methods: Hyperglycemia was induced by using the intraperitoneal injection method with 350 mg/BW streptozotocin on days one, three, and five. The regeneration of the zebrafish's caudal fin was observed on day 5 after amputation using a stereomicrosco
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10

Johnson, S. L., and J. A. Weston. "Temperature-sensitive mutations that cause stage-specific defects in Zebrafish fin regeneration." Genetics 141, no. 4 (1995): 1583–95. http://dx.doi.org/10.1093/genetics/141.4.1583.

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Abstract When amputated, the fins of adult zebrafish rapidly regenerate the missing tissue. Fin regeneration proceeds through several stages, including wound healing, establishment of the wound epithelium, recruitment of the blastema from mesenchymal cells underlying the wound epithelium, and differentiation and outgrowth of the regenerate. We screened for temperature-sensitive mutations that affect the regeneration of the fin. Seven mutations were identified, including five that fail to regenerate their fins, one that causes slow growth during regeneration, and one that causes dysmorphic bump
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11

Saxena, Sandeep, Sachin K. Singh, Mula G. Meena Lakshmi, et al. "Proteomic Analysis of Zebrafish Caudal Fin Regeneration." Molecular & Cellular Proteomics 11, no. 6 (2012): M111.014118. http://dx.doi.org/10.1074/mcp.m111.014118.

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12

Hayati, Farida. "Centella asiatica (L.) Fraction Increases the Caudal Fin Regeneration of Zebra Fish (Danio rerio) through the Modulation of Superoxide Dismutase (SOD) Antioxidant Enzyme." Tropical Journal of Natural Product Research 9, no. 4 (2025): 1813. https://doi.org/10.26538/tjnpr/v9i4.54.

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Centella asiatica is a herbal plant with established wound-healing properties. This study aimed to assess the asiaticoside content in different fractions of C. asiatica and examine its effects on zebrafish caudal fin regeneration, with an emphasis on the enhancement of the Superoxide Dismutase (SOD) antioxidant enzyme. The C. asiatica leaves were extracted by maceration using 96% ethanol and fractionated with vacuum liquid chromatography using ethyl acetate and 96% ethanol. Reversed-phase HPLC was used to determine the asiaticoside. Zebrafish were divided into 3 groups (n = 20 fish/group): the
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13

Darniwa, Adisty Virakawugi, Tri Cahyanto, and Savira Ngesti Rahayu. "Effect of Light Intensity on Zebra Fish (Danio rerio) Cell Regeneration." Jurnal Pijar Mipa 19, no. 2 (2024): 260–64. http://dx.doi.org/10.29303/jpm.v19i2.4364.

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Zebrafish (Danio rerio) is one of the model animals in cell regeneration studies because it has a high ability to regenerate tissue structures, one of which is its caudal fin. This study was conducted to determine the different light interventions on the regeneration of the caudal fin of zebrafish. The research method used is an experimental study with the observed parameters, including specific growth, absolute weight gain, length increase, and survival. A total of 28 male wild-type zebrafish were used in this study at the age of 3 months. The amputated zebrafish on its caudal fin was placed
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14

Ullah, Kalim, Rakhshanda Rani, Fouzia Shaheen, and Faisal Tasleem. "Teleost Caudal Fin Development and Regeneration: Mechanisms, Models, and Therapeutic Potential." Asian Journal of Fisheries and Aquatic Research 26, no. 12 (2024): 1–11. http://dx.doi.org/10.9734/ajfar/2024/v26i12840.

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The caudal fin of teleost fish, a fundamental locomotive structure, has received considerable attention due to its extraordinary capacity for regeneration. Teleosts' ability to regenerate their caudal fins involves complex interactions between various signaling pathways, growth factors, and transcription factors that organize wound healing, cell proliferation, and tissue redevelopment. Key pathways implicated in these processes include Wnt/β-catenin, Hedgehog, FGF, and Notch signaling, which not only regulate the proliferation and differentiation of resident stem cells but also ensure the spat
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15

Derron Ricardo Taite and Mohammad Kutub Ali. "Impact of green and black tea extracts on swimming performance and caudal fin regeneration in adult zebrafish (Danio rerio) following amputation." World Journal of Advanced Pharmaceutical and Life Sciences 7, no. 2 (2024): 001–8. http://dx.doi.org/10.53346/wjapls.2024.7.2.0037.

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This study investigates the effects of green tea and black tea extracts on swimming performance and caudal fin regeneration in adult zebrafish (Danio rerio) following caudal fin amputation. Zebrafish were treated with either tea extract for 14 days, with applications administered three times daily. Swimming performance was assessed against water currents. Results indicated that green tea-treated fish exhibited the greatest resistance to water flow, primarily occupying the high-force zone during a 15-minute exercise session, while black tea-treated fish were mostly found in middle and lower zon
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16

Ochandio, BS, IJ Bechara, and PP Parise-Maltempi. "Dexamethasone action on caudal fin regeneration of carp Cyprinus carpio (Linnaeus, 1758)." Brazilian Journal of Biology 75, no. 2 (2015): 442–50. http://dx.doi.org/10.1590/1519-6984.16813.

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Studies have demonstrated that the prolonged use of corticoids can delay the healing process, affecting re-epithelialization, neovascularization and collagen synthesis. As the fins of teleost fish contain a large amount of collagen, the aim of the present study was to investigate the effect of dexamethasone (anti-inflammatory and glucocorticoid steroid widely used in the treatment of rheumatic diseases) during the regeneration process in the caudal fin of specimens of carp (Cyprinus carpio). For such, two glass aquaria were used – one for a group of fish treated with dexamethasone (Henrifarma)
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17

Wang, Wei, Chi-Kuo Hu, An Zeng, et al. "Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates." Science 369, no. 6508 (2020): eaaz3090. http://dx.doi.org/10.1126/science.aaz3090.

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Vertebrates vary in their ability to regenerate, and the genetic mechanisms underlying such disparity remain elusive. Comparative epigenomic profiling and single-cell sequencing of two related teleost fish uncovered species-specific and evolutionarily conserved genomic responses to regeneration. The conserved response revealed several regeneration-responsive enhancers (RREs), including an element upstream to inhibin beta A (inhba), a known effector of vertebrate regeneration. This element activated expression in regenerating transgenic fish, and its genomic deletion perturbed caudal fin regene
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18

Varga, M., M. Sass, D. Papp, et al. "Autophagy is required for zebrafish caudal fin regeneration." Cell Death & Differentiation 21, no. 4 (2013): 547–56. http://dx.doi.org/10.1038/cdd.2013.175.

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19

Schebesta, Michael, Ching-Ling Lien, Felix B. Engel, and Mark T. Keating. "Transcriptional Profiling of Caudal Fin Regeneration in Zebrafish." TSW Development & Embryology 1 (June 2, 2006): 38–54. http://dx.doi.org/10.1100/tswde2006.124.

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20

Cao, Zigang, Chen Guo, Guilan Chen, et al. "Shikonin Inhibits Fin Regeneration in Zebrafish Larvae." Cells 11, no. 20 (2022): 3187. http://dx.doi.org/10.3390/cells11203187.

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Shikonin is a naphthoquinone compound extracted from Chinese comfrey for treating cancer. However, there are few reports on its research on vertebrate tissue regeneration. Zebrafish is an ideal model for studying organ regeneration. In this study, we found that 3-dpf of zebrafish larvae exposed to shikonin at concentrations of 0.2, 0.3, and 0.4 mg/L showed increasingly inhibited regeneration of the tail fin. Immunohistochemical staining showed that shikonin exposure from 6 to 12 hpa increased the number of apoptotic cells in the caudal fin wound of larvae and decreased the number of proliferat
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21

Li, Junyan, Xin Yao, and Hangchen Liu. "Identifying the role of circular RNA in zebrafish fin regeneration." Theoretical and Natural Science 72, no. 1 (2025): 151–57. https://doi.org/10.54254/2753-8818/2024.19365.

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Circular RNA (circRNA) is a class of RNA with circular structures and diverse functions. In recent years, they have emerged as a key regulatory molecule with abilities to regulate stem cell differentiation and other components of the cell cycle including tumor suppression and cell cycle progression. Yet their functions in regeneration are under-investigated. We chose zebrafish as a model organism due to their remarkable regenerative capabilities, and susceptibility to genetic modifications. This study aims to explore the role of circRNAs in zebrafish caudal fin regeneration, with a specific fo
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22

Rabinowitz, Jeremy S., Aaron M. Robitaille, Yuliang Wang, et al. "Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish." Proceedings of the National Academy of Sciences 114, no. 5 (2017): E717—E726. http://dx.doi.org/10.1073/pnas.1620755114.

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Regeneration requires cells to regulate proliferation and patterning according to their spatial position. Positional memory is a property that enables regenerating cells to recall spatial information from the uninjured tissue. Positional memory is hypothesized to rely on gradients of molecules, few of which have been identified. Here, we quantified the global abundance of transcripts, proteins, and metabolites along the proximodistal axis of caudal fins of uninjured and regenerating adult zebrafish. Using this approach, we uncovered complex overlapping expression patterns for hundreds of molec
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23

Zodrow, J. M. "2,3,7,8-Tetrachlorodibenzo-p-dioxin Inhibits Zebrafish Caudal Fin Regeneration." Toxicological Sciences 76, no. 1 (2003): 151–61. http://dx.doi.org/10.1093/toxsci/kfg205.

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24

SARRASJR, M., R. THUMMEL, and A. GODMAN. "Role of Hox genes in zebrafish caudal fin regeneration." Matrix Biology 25 (November 2006): S25. http://dx.doi.org/10.1016/j.matbio.2006.08.071.

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25

Darniwa, Adisty Virakawugi, Tri Cahyanto, and Siti Nurul Hidayah. "Effect of Mango Leaf Shoot Extract (Mangifera indica L.) on Zebrafish (Danio rerio) Cell Regeneration Induced by Hyperglicemia." Jurnal Ilmu Hayat 5, no. 2 (2022): 43. http://dx.doi.org/10.17977/um061v5i22021p43-57.

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Abstract. In many cases, diabetics often have difficulty in wound healing and lead to amputation. Hyperglycemia is an early symptom of diabetic which is characterized by high blood glucose levels. Cell regeneration is one of part by wound healing process. Mango plants have benefits as medicinal plants because they have secondary metabolites that can help heal wounds. The purpose of this study was to determine the effect of mango leaf shoot extract on blood glucose levels of zebrafish (Danio rerio) hyperglycemia due to alloxan and glucose induction and role of mango leaf shoot extract on zebraf
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Derron Ricardo Taite, Imani Natasia Hewitt, and Mohammad Kutub Ali. "The effect of resveratrol and alcohol on zebrafish caudal fin regeneration." World Journal of Advanced Pharmaceutical and Life Sciences 6, no. 2 (2024): 017–20. http://dx.doi.org/10.53346/wjapls.2024.6.2.0031.

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Introduction: Wine, an alcoholic beverage derived from the fermentation of fruit juices, typically grapes, has been a popular drink since ancient times. Resveratrol, a polyphenol found in grapes, is associated with growth inhibition. There are conflicting reports on the overall health benefits of regular wine consumption, with some sources suggesting positive effects on growth, while others claim inhibitory effects. This study investigates the effects of red wine, grape juice, and resveratrol on growth and wound healing using adult zebrafish. Method: The study assessed growth through the regen
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27

Sakthivel, Selvakumar, and Annadurai Gurusamy. "Evaluation of Bacterial Infections on Caudal Fin Regeneration in Zebrafish and Effect of Restorative Plants." International Journal of Current Pharmaceutical Review and Research 8, no. 2 (2017): 198–205. https://doi.org/10.5281/zenodo.12677988.

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In this present work to exploring how the recovery limit in the time of the caudal balance recovery of ordinary and bacterialdisease (Pseudomonas aeruginosa, Flexibacter columnaris and Aeromonas hydrophila) in zebra fish and relativeexamination of focusing on tainting microorganisms by the the plants (Azadirachta indica, Moringa oleifera and Cynodondactylon) extracts and antimicrobials. Intraperitoneal infusion and water dissolving strategy were utilizing for bacterialdisease in zebrafish followed by standard protocol. Four distinctive plant extracts utilizing for biocidal movement. In theintr
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28

Akimenko, M. A., S. L. Johnson, M. Westerfield, and M. Ekker. "Differential induction of four msx homeobox genes during fin development and regeneration in zebrafish." Development 121, no. 2 (1995): 347–57. http://dx.doi.org/10.1242/dev.121.2.347.

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To study the genetic regulation of growth control and pattern formation during fin development and regeneration, we have analysed the expression of four homeobox genes, msxA, msxB, msxC and msxD in zebrafish fins. The median fin fold, which gives rise to the unpaired fins, expresses these four msx genes during development. Transcripts of the genes are also present in cells of the presumptive pectoral fin buds. The most distal cells, the apical ectodermal ridge of the paired fins and the cleft and flanking cells of the median fin fold express all these msx genes with the exception of msxC. Mese
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29

Parasuraman, Rajeshwari, and Sathya Narayanan Govindarajulu. "Enhancement of caudal fin regeneration in diabetic zebrafish: An insight into proangiogenic potential of bromelain." Indian Journal of Physiology and Pharmacology 67 (March 29, 2023): 3–7. http://dx.doi.org/10.25259/ijpp_90_2022.

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Objectives: Diabetes mellitus is a chronic metabolic disease that is characterised by hyperglycaemia, altered lipids, carbohydrates and protein metabolism, and in the long-term, with eye, kidney, cardiovascular and neurological complications. Poor wound healing is one of the major complications faced by diabetes mellitus patients. Angiogenesis is critical for tissue regeneration and wound healing. Impaired angiogenesis may lead to poor blood flow to the wound and hence delayed wound healing. Hence, it is important to find an antidote to speed up wound healing. Hence, this study focuses on the
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30

Sousa, Sara, Nuno Afonso, Mariana Fonseca, and António Jacinto. "19-P025 Bone dynamics during adult zebrafish caudal fin regeneration." Mechanisms of Development 126 (August 2009): S298. http://dx.doi.org/10.1016/j.mod.2009.06.813.

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31

Shi, Xiujuan, Neng Yan, Guangle Niu, et al. "In vivo monitoring of tissue regeneration using a ratiometric lysosomal AIE probe." Chemical Science 11, no. 12 (2020): 3152–63. http://dx.doi.org/10.1039/c9sc06226b.

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32

Thompson, John D., Jianhong Ou, Nutishia Lee, et al. "Identification and requirements of enhancers that direct gene expression during zebrafish fin regeneration." Development 147, no. 14 (2020): dev191262. http://dx.doi.org/10.1242/dev.191262.

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ABSTRACTTo identify candidate tissue regeneration enhancer elements (TREEs) important for zebrafish fin regeneration, we performed ATAC-seq from bulk tissue or purified fibroblasts of uninjured and regenerating caudal fins. We identified tens of thousands of DNA regions from each sample type with dynamic accessibility during regeneration, and assigned these regions to proximal genes with corresponding expression changes by RNA-seq. To determine whether these profiles reveal bona fide TREEs, we tested the sufficiency and requirements of several sequences in stable transgenic lines and mutant li
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Shao, Jinping, Dongyan Chen, Qijun Ye, Jianlin Cui, Yuhao Li, and Lei Li. "Tissue regeneration after injury in adult zebrafish: The regenerative potential of the caudal fin." Developmental Dynamics 240, no. 5 (2011): 1271–77. http://dx.doi.org/10.1002/dvdy.22603.

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Duarte da Silva, Kiara Cândido, William Franco Carneiro, Bárbara do Carmo Rodrigues Virote, et al. "Evaluation of the Anti-Inflammatory and Antioxidant Potential of Cymbopogon citratus Essential Oil in Zebrafish." Animals 14, no. 4 (2024): 581. http://dx.doi.org/10.3390/ani14040581.

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This study explored the protective capacity of the essential oil (EO) of Cymbopogon citratus against oxidative stress induced by hydrogen peroxide (H2O2) and the inflammatory potential in zebrafish. Using five concentrations of EO (0.39, 0.78, 1.56, 3.12, and 6.25 μg/mL) in the presence of 7.5 mM H2O2, we analyzed the effects on neutrophil migration, caudal fin regeneration, cellular apoptosis, production of reactive oxygen species (ROS), and activities of the antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione S-transferase (GST) after 96 h of exposure. A significa
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35

Ge, Chenkai, Zhijun Ye, Weitao Hu, et al. "Effects of pyrazosulfuron-ethyl on caudal fin regeneration in zebrafish larvae." Ecotoxicology and Environmental Safety 290 (January 2025): 117552. https://doi.org/10.1016/j.ecoenv.2024.117552.

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Zarnescu, Otilia, Simona Stavri, and Lucia Moldovan. "Inhibition of caudal fin regeneration in Corydoras aeneus by lithium chloride." Micron 46 (March 2013): 66–75. http://dx.doi.org/10.1016/j.micron.2012.12.009.

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37

Azevedo, Ana, Rita Mateus, Sara Sousa, Miguel Ferreira, António Jacinto, and Leonor Saúde. "19-P038 Regeneration in zebrafish caudal fin: The role of telomerase." Mechanisms of Development 126 (August 2009): S302. http://dx.doi.org/10.1016/j.mod.2009.06.826.

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Sun, Liwei, Linqi Gu, Hana Tan та ін. "Effects of 17α‑ethinylestradiol on caudal fin regeneration in zebrafish larvae". Science of The Total Environment 653 (лютий 2019): 10–22. http://dx.doi.org/10.1016/j.scitotenv.2018.10.275.

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Park, Hyung-Geun, and Min-Kyeong Yeo. "Effects of TiO2 nanoparticles and nanotubes on zebrafish caudal fin regeneration." Molecular & Cellular Toxicology 9, no. 4 (2013): 375–83. http://dx.doi.org/10.1007/s13273-013-0046-8.

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40

Li, Jing, Yousef Sultan, Yaoyi Sun, Shuqiang Zhang, Yang Liu та Xiaoyu Li. "Expression analysis of Hsp90α and cytokines in zebrafish caudal fin regeneration". Developmental & Comparative Immunology 116 (березень 2021): 103922. http://dx.doi.org/10.1016/j.dci.2020.103922.

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41

Hou, Tingting, Zaizhao Wang, Kui Tang, et al. "The Fin-Improving Effects of Fucosylated Chondroitin Sulfate from Green and Purple Apostichopus japonicus on Caudal Fin Regeneration of Zebrafish Larvae." Aquaculture Research 2023 (February 11, 2023): 1–11. http://dx.doi.org/10.1155/2023/9258423.

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This study investigated the capability for fin regeneration in zebrafish larvae with the mechanism of FCS isolated from green and purple sea cucumbers Apostichopus japonicus (G-FCS and P-FCS). HPGPC determined that mean molecular weight of purified G-FCS and P-FCS is 19.5 and 18.8 kDa, and the FT-IR spectrum displayed similar characteristic absorption peaks. AFM images presented that G-FCS was shown as a spherical polysaccharide, while P-FCS molecules exhibited elongated chains. For the regeneration examination, FCS increased the regrowth area of the larval fin at 48 hours postamputation with
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Kizil, Caghan, Georg W. Otto, Robert Geisler, Christiane Nüsslein-Volhard, and Christopher L. Antos. "Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration." Developmental Biology 325, no. 2 (2009): 329–40. http://dx.doi.org/10.1016/j.ydbio.2008.09.032.

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43

Tawk, Marcel, Catherine Joulie, and Sophie Vriz. "Zebrafish Hsp40 and Hsc70 genes are both induced during caudal fin regeneration." Mechanisms of Development 99, no. 1-2 (2000): 183–86. http://dx.doi.org/10.1016/s0925-4773(00)00478-0.

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Lee, Yunkyoung, Dohee Kim, and Chang-Joong Lee. "Suppressive effects of valproic acid on caudal fin regeneration in adult zebrafish." Animal Cells and Systems 24, no. 6 (2020): 349–58. http://dx.doi.org/10.1080/19768354.2020.1860126.

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Saxena, Sandeep, Sruthi Purushothaman, Vuppalapaty Meghah, et al. "Role of annexin gene and its regulation during zebrafish caudal fin regeneration." Wound Repair and Regeneration 24, no. 3 (2016): 551–59. http://dx.doi.org/10.1111/wrr.12429.

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Gu, Linqi, Li Tian, Gan Gao, et al. "Inhibitory effects of polystyrene microplastics on caudal fin regeneration in zebrafish larvae." Environmental Pollution 266 (November 2020): 114664. http://dx.doi.org/10.1016/j.envpol.2020.114664.

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Padhi, Bhaja K., Lucille Joly, Patricia Tellis, et al. "Screen for genes differentially expressed during regeneration of the zebrafish caudal fin." Developmental Dynamics 231, no. 3 (2004): 527–41. http://dx.doi.org/10.1002/dvdy.20153.

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48

Quoseena, Mir, Sowmya Vuppaladadium, Shahid Hussain, Sarena Banu, Swarna Bharathi, and Mohammed M. Idris. "Functional role of annexins in zebrafish caudal fin regeneration – A gene knockdown approach in regenerating tissue." Biochimie 175 (August 2020): 125–31. http://dx.doi.org/10.1016/j.biochi.2020.05.014.

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49

Audira, Gilbert, Michael Edbert Suryanto, Kelvin H. C. Chen, et al. "Acute and Chronic Effects of Fin Amputation on Behavior Performance of Adult Zebrafish in 3D Locomotion Test Assessed with Fractal Dimension and Entropy Analyses and Their Relationship to Fin Regeneration." Biology 11, no. 7 (2022): 969. http://dx.doi.org/10.3390/biology11070969.

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Abstract:
The fin is known to play an important role in swimming for many adult fish, including zebrafish. Zebrafish fins consist of paired pectoral and pelvic with unpaired dorsal, anal, and caudal tail fins with specific functions in fish locomotion. However, there was no study comparing the behavior effects caused by the absence of each fin. We amputated each fin of zebrafish and evaluated their behavior performance in the 3D locomotion test using fractal dimension and entropy analyses. Afterward, the behavior recovery after the tail fin amputation was also evaluated, together with the fin regenerati
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Vijayakumar, Parameswaran, M. Leonor Cancela, and Vincent Laizé. "Isolation, Culture, and Differentiation of Blastema Cells from the Regenerating Caudal Fin of Zebrafish." Fishes 5, no. 1 (2020): 6. http://dx.doi.org/10.3390/fishes5010006.

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Abstract:
The caudal fin of teleost fish has become an excellent system for investigating the mechanisms of epimorphic regeneration. Upon amputation of the caudal fin, a mass of undifferentiated cells, called blastema, proliferate beneath the wound-epidermis and differentiate into various cell types to faithfully restore the missing fin structures. Here we describe a protocol that can be used to isolate and culture blastema cells from zebrafish. Primary cultures were initiated from 36 h post-amputation (hpa) blastema and optimal cell growth was achieved using L-15 medium supplemented with 5% fetal bovin
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