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Journal articles on the topic 'CCAE'

Author: Grafiati

Published: 4 June 2021

Last updated: 19 February 2022

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1

GUAN, SHENG-UEI, and SHU ZHANG. "A FAMILY OF CONTROLLABLE CELLULAR AUTOMATA FOR PSEUDORANDOM NUMBER GENERATION." International Journal of Modern Physics C 13, no. 08 (2002): 1047–73. http://dx.doi.org/10.1142/s0129183102003863.

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In this paper, we present a family of novel Pseudorandom Number Generators (PRNGs) based on Controllable Cellular Automata (CCA) CCA0, CCA1, CCA2 (NCA), CCA3 (BCA), CCA4 (asymmetric NCA), CCA5, CCA6 and CCA7 PRNGs. The ENT and DIEHARD test suites are used to evaluate the randomness of these CCA PRNGs. The results show that their randomness is better than that of conventional CA and PCA PRNGs while they do not lose the structure simplicity of 1D CA. Moreover, their randomness can be comparable to that of 2D CA PRNGs. Furthermore, we integrate six different types of CCA PRNGs to form CCA PRNG gr

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Zanini, Fábio D., Everton S. Ameno, Sidney O. Magaldi, and Ruben A. Lamar. "Colesteatoma de conduto auditivo externo: relato de caso." Revista Brasileira de Otorrinolaringologia 71, no. 1 (2005): 91–93. http://dx.doi.org/10.1590/s0034-72992005000100016.

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Os autores apresentam um caso de colesteatoma de conduto auditivo externo (CCAE) com extensa invasão da mastóide, mas estando preservadas a membrana timpânica e a cadeia ossicular. Como único sintoma apresentava otorréia crônica. O diagnóstico da lesão foi clínico, sendo o seu estadiamento e planejamento cirúrgico realizados através da tomografia computadorizada. Como tratamento procedeu-se a mastoidectomia radical modificada associada à meatoplastia. O CCAE, por seu caráter insidioso e correlação topográfica com estruturas nobres, deve ser sempre lembrado no diagnóstico diferencial das lesões

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Cámara, Beatriz, Patricia Nikodem, Piotr Bielecki, Roberto Bobadilla, Howard Junca, and Dietmar H. Pieper. "Characterization of a Gene Cluster Involved in 4-Chlorocatechol Degradation by Pseudomonas reinekei MT1." Journal of Bacteriology 191, no. 15 (2009): 4905–15. http://dx.doi.org/10.1128/jb.00331-09.

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ABSTRACT Pseudomonas reinekei MT1 has previously been reported to degrade 4- and 5-chlorosalicylate by a pathway with 4-chlorocatechol, 3-chloromuconate, 4-chloromuconolactone, and maleylacetate as intermediates, and a gene cluster channeling various salicylates into an intradiol cleavage route has been reported. We now report that during growth on 5-chlorosalicylate, besides a novel (chloro)catechol 1,2-dioxygenase, C12OccaA, a novel (chloro)muconate cycloisomerase, MCIccaB, which showed features not yet reported, was induced. This cycloisomerase, which was practically inactive with muconate,

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Wang, Xin, Yuanyi Chen, Wei Ruan, Qiang Gao, Guode Ying, and Li Dong. "Intelligent Detection and Recovery of Missing Electric Load Data Based on Cascaded Convolutional Autoencoders." Scientific Programming 2020 (December 7, 2020): 1–20. http://dx.doi.org/10.1155/2020/8828745.

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Under the background of Energy Internet, the ever-growing scale of the electric power system has brought new challenges and opportunities. Numerous categories of measurement data, as the cornerstone of communication, play a crucial role in the security and stability of the system. However, the present sampling and transmission equipment inevitably suffers from data missing, which seriously degrades the stable operation and state estimation. Therefore, in this paper, we consider the load data as an example and first develop a missing detection algorithm in terms of the absolute difference seque

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Cotrado Flores, Dina Marlene. "Elaboración de curvas de fragilidad de muros de ductilidad limitada de 10 cm. de espesor, basados en ensayos experimentales; período 2011 - 2015." REVISTA VERITAS ET SCIENTIA - UPT 6, no. 1 (2017): 665–71. http://dx.doi.org/10.47796/ves.v6i1.199.

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La presente investigación tuvo por finalidad contribuir en el estudio de vulnerabilidad sísmica en edificios de muros de ductilidad limitada. Para ello, se ha elaboró curvas de fragilidad en muros de ductilidad limitada de 10 cm de espesor según PACT del FEMA P-58. Se recopiló información de 20 ensayos experimentales realizados en el laboratorio de estructuras del Centro Peruano Japonés de Investigaciones Sísmicas y Mitigación de Desastres de la Universidad Nacional de Ingeniería. Las curvas de fragilidad expresan la probabilidad de que un muro de ductilidad limitada alcance o exceda un estado

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Kern, David M., M. Soledad Cepeda, and Anthony G. Sena. "Oral Opioid Prescribing Trends in the United States, 2002–2018." Pain Medicine 21, no. 11 (2020): 3215–23. http://dx.doi.org/10.1093/pm/pnaa313.

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Abstract Objective To conduct a retrospective analysis of sequential cross-sectional data of opioid prescribing practices in patients with no prior history of opioid use. Methods Individuals filling an oral opioid prescription who had 1 year of prior observation were identified from four different administrative claims databases for the period between January 1, 2002, and December 31, 2018: IBM MarketScan® Commercial Database (CCAE), Multi-State Medicaid Database (MDCD), Medicare Supplemental Database (MDCR), and Optum© De-Identified Clinformatics® Data Mart Database. Outcomes included inciden

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Li, Youru, Zhenfeng Zhu, Haiyan Wu, Silu Ding, and Yao Zhao. "CCAE: Cross-field categorical attributes embedding for cancer clinical endpoint prediction." Artificial Intelligence in Medicine 107 (July 2020): 101915. http://dx.doi.org/10.1016/j.artmed.2020.101915.

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Liu, Tian Mo, Yu Liu, Li Wei Lu, and Fu Sheng Pan. "Upper-Bound Analysis for Change-Channel Angular Extrusion." Materials Science Forum 610-613 (January 2009): 838–43. http://dx.doi.org/10.4028/www.scientific.net/msf.610-613.838.

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Deformation of the material during 90° change-channel angular extrusion (CCAE) process is analyzed using upper-bound theorem. The mathematical model was established which includes the effect of friction between the sample and inner surface of the die, radius of inner and outer corner of the die, and the dead metal zone on the deformation patterns during change-channel angular extrusion deformation process. The model of parameters is explored in relation to the deformation of the material during the change-channel angular extrusion process. Results showed that the extrusion force increased with

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Da Silva, Samuel Ferreira, Giovanni De Oliveira Garcia, Edvaldo Fialho Dos Reis, and Leandro Pin Dalvi. "USO AGRÍCOLA DA VINHAÇA PARA PRODUÇÃO DE FORRAGEM DE MILHO DURANTE TRÊS ANOS DE CULTIVO1." IRRIGA 1, no. 1 (2018): 59. http://dx.doi.org/10.15809/irriga.2016v1n1p59-69.

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USO AGRÍCOLA DA VINHAÇA PARA PRODUÇÃO DE FORRAGEM DE MILHO DURANTE TRÊS ANOS DE CULTIVO1 SAMUEL FERREIRA DA SILVA2; GIOVANNI DE OLIVEIRA GARCIA3; EDVALDO FIALHO DOS REIS3 E LEANDRO PIN DALVI4 1Trabalho extraído da Tese de Doutorado do primeiro autor, Bolsista da FAPES.2Doutorando em Produção Vegetal, Centro de Ciências Agrárias e Engenharias da Universidade Federal do Espírito Santo - CCAE-UFES, CEP: 29500-000, Alegre, ES. E-mail: samuelfd.silva@yahoo.com.br.3Prof. Doutor, Departamento de Engenharia Rural, CCAE-UFES, Alegre, ES. E-mail: giovanni.garcia@ufes.br; edreis@cca.ufes.br.4Prof. Doutor

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Teixeira, Célia Regina, Danieli Almeida de Araújo Rodrigues Bulhões, and Merian Aparecida Poluceno da Silva. "Memórias da avaliação da aprendizagem: o caderno de memórias como instrumento de reflexão e autoavaliação." Dialogia, no. 26 (June 7, 2017): 109–19. http://dx.doi.org/10.5585/dialogia.n26.7095.

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Este trabalho tem como objetivo ocasionar uma reflexo acerca da avaliao das aprendizagens, a partir dos registros nos cadernos de Memrias dos alunos do curso de pedagogia, para isto, destacamos as reflexes realizadas atravs das vivncias decorrentes da disciplina de Avaliao Educacional, ministrada no curso de Pedagogia, Centro de Cincias Aplicadas e Educao CCAE, da Universidade Federal da Paraba UFPB. A avaliao das aprendizagens vem sendo cada vez mais objeto de discusso entre estudiosos e profissionais da educao. E para demostrar esse interesse, foi proposto como avaliao da aprendizagem constr

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Anagnostis, Panagiotis, Christos V. Rizos, Ioannis Skoumas, et al. "Prevalence of Non-coronary Heart Disease in Patients with Familial Hypercholesterolemia: An Analysis from the HELLAS-FH." Current Pharmaceutical Design 27, no. 21 (2021): 2537–44. http://dx.doi.org/10.2174/1381612827666210216151645.

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Aims: Despite the established link between familial hypercholesterolemia (FH) and increased risk of coronary heart disease (CHD), its association with other common atherosclerotic and metabolic diseases has not been extensively studied. The aim of this study was to report the prevalence of peripheral arterial disease (PAD) [i.e., common carotid artery disease (CCAD) and lower extremity arterial disease (LEAD)], aortic valve stenosis, chronic kidney disease (CKD) and non-alcoholic fatty liver disease (NAFLD) in patients with FH. Materials & Methods: This was a cross-sectional study retrievi

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Isaia, Geraldo Cechella, Raúl Luis Zerbino, Antonio Luiz Guerra Gastaldini, and Gemma Rodrigues Sensale. "Viabilidade do emprego de cinza de casca de arroz natural em concreto estrutural (parte II): durabilidade." Ambiente Construído 17, no. 2 (2017): 233–52. http://dx.doi.org/10.1590/s1678-86212017000200155.

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Resumo Os resíduos incorporados aos materiais de construção devem ser usados, se possível, sem processamentos, para evitar o aumento dos impactos ambientais e custos adicionais. A cinza de casca de arroz (CCA) é uma pozolana que deve ser previamente moída, para aumentar a finura e a reatividade com o cimento, quando empregada como material cimentício. Este trabalho estuda cinza de casca de arroz natural (CCAN) sem processamento em substituição parcial de 15% de cimento, em massa, para uso em concreto estrutural, cominuída por moagem conjunta com os agregados no tambor da betoneira. Na parte I

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Hu, Tianyan, Eric Sarpong, Yan Song, et al. "1479. Incidence of Acute Otitis Media in Children in the United States before and after the introduction of Pneumococcal Conjugate Vaccines (PCV7 and PCV13) during 1998-2018." Open Forum Infectious Diseases 7, Supplement_1 (2020): S740—S741. http://dx.doi.org/10.1093/ofid/ofaa439.1660.

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Abstract Background Acute otitis media (AOM) leads to considerable healthcare resource utilization in children. Streptococcus pneumoniae is an important cause of AOM. Merck is developing V114, an investigational 15-valent PCV that contains PCV13 serotypes as well as 22F and 33F. To demonstrate the potential value of V114, it is important to estimate the remaining clinical burden associated with AOM. This study estimated AOM incidence rates (IRs) before and after the introduction of 7-valent and 13-valent pneumococcal conjugate vaccines (PCV7 and PCV13) in the US. Methods This was a retrospecti

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Carmona, L., J. Weaver, E. Burn, et al. "SAT0138 DRUG-RELATED PANCYTOPENIA AND LEUKOPENIA IN RHEUMATOID ARTHRITIS: ARE ALL CSDMARDS EQUAL?" Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1006–7. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4075.

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Background:Cytopenia is a known side-effect of conventional synthetic disease modifying anti-rheumatic drugs (csDMARDs) in rheumatoid arthritis (RA). There is a lack of data on the comparative risk of cytopenia with different csDMARDs.Objectives:To assess the comparative risk of leukopenia and pancytopenia for the most frequently used first-line csDMARDs: methotrexate (MTX), hydroxychloroquine (HCQ), sulphasalazine (SSZ), and leflunomide (LEF).Methods:The study used data from 7 databases from 4 countries: CCAE, MDCR, Optum, IQVIA Ambulatory EMR (US); IQVIA THIN IMRD EMR (UK); IQVIA Disease Ana

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Brito, José Raimundo Fraga de, Leandro Pin Dalvi, Leonardo Mardgan, Hugo José Gonçalves dos Santos Junior, Julielson Oliveira Ataide, and Hugo Bolsoni Zago. "Ureia tradicional e protegida no desenvolvimento e produção de forragem de milho." Revista Ibero-Americana de Ciências Ambientais 11, no. 3 (2020): 60–65. http://dx.doi.org/10.6008/cbpc2179-6858.2020.003.0006.

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O Brasil é destaque junto ao cenário mundial na produção de milho, entretanto o uso de cultivares pouco adaptadas as regiões produtoras, além do baixo uso de fertilizantes nitrogenados em cobertura, reduz o potencial produtivo das áreas cultivadas com o milho no Brasil. Dessa forma, objetivou-se avaliar o crescimento e produção do milho (Zea mays L.) híbrido RefúgioMax®, em função de fontes de adubos nitrogenados (N) (ureia tradicional, ureia protegida). O experimento foi conduzido em campo, na área experimental do CCAE (Centro de Ciências Agrárias e Engenharias da UFES), localizada no municíp

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Duarte-Salles, T., M. Recalde, J. Weaver, et al. "SAT0134 COMPARATIVE RISK OF CANCER ASSOCIATED WITH FIRST-LINE DMARDS USE IN RHEUMATOID ARTHRITIS: REAL WORLD EVIDENCE FROM THE OHDSI NETWORK." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1004.1–1004. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3866.

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Background:Conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) are recommended as first line treatment for rheumatoid arthritis (RA) patients, but limited information exists on the comparative risk of cancer associated with their use.Objectives:To compare the risk of incident overall (excluding non-melanoma skin) and site-specific cancers (colorectal, lung, lymphoma, leukaemia) associated with first-line use of csDMARDs in patients with RA.Methods:We conducted a multinational cohort study informed by data from 7 healthcare databases including claims and electronic medical r

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Prats-Uribe, A., B. Illingens, D. Vizcaya, et al. "SAT0131 CARDIO- AND CEREBROVASCULAR RISK WITH CONVENTIONAL SYNTHETIC DISEASE-MODIFYING ANTIRHEUMATIC DRUGS (CSDMARDS) IN RHEUMATOID ARTHRITIS (RA): A REAL-WORLD COMPARATIVE ASSESSMENT." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1002. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3463.

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Background:RA is associated with an increased cardiovascular (CV) risk. csDMARDs are first-line treatments for RA and can mitigate this risk, but limited data exist on their CV effects. Previous trials have reported protective effects for methotrexate (MTX) and hydroxychloroquine (HCQ), but no similar data exist on sulfasalazine (SSZ) or leflunomide (LEF).Objectives:To assess the comparative effect of csDMARDs on the risk of myocardial infarction (MI) and stroke in RA patientsMethods:Data from 6 claims/electronic health records databases across Germany, US, and UK, all mapped to the Observatio

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Patel, Sparsh, Po-Yin Cheung, Tze-Fun Lee, et al. "Asynchronous ventilation at 120 compared with 90 or 100 compressions per minute improves haemodynamic recovery in asphyxiated newborn piglets." Archives of Disease in Childhood - Fetal and Neonatal Edition 105, no. 4 (2019): 357–63. http://dx.doi.org/10.1136/archdischild-2018-316610.

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ObjectiveTo determine whether different chest compression (CC) rates during continuous CC with asynchronous ventilations (CCaV) reduce time to return of spontaneous circulation (ROSC) and improved haemodynamic recovery in piglets aged 24–72 hours with asphyxia-induced asystole.MethodsThirty piglets (aged 24–72 hours) were anaesthetised, intubated, instrumented and exposed to 30 min normocapnic hypoxia followed by asphyxia. Piglets were randomised into four groups: CCaV with CC rate of 90 (CCaV+90, n=8), 100 (CCaV+100, n=8) or 120 compressions per minute (CCaV+120, n=8), and a sham-operated gro

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Hiramatsu, Masafumi, Tomohito Hishikawa, Koji Tokunaga, et al. "Combined gene therapy with vascular endothelial growth factor plus apelin in a chronic cerebral hypoperfusion model in rats." Journal of Neurosurgery 127, no. 3 (2017): 679–86. http://dx.doi.org/10.3171/2016.8.jns16366.

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OBJECTIVEThe aim of this study was to evaluate whether combined gene therapy with vascular endothelial growth factor (VEGF) plus apelin during indirect vasoreconstructive surgery enhances brain angiogenesis in a chronic cerebral hypoperfusion model in rats.METHODSA chronic cerebral hypoperfusion model induced by the permanent ligation of bilateral common carotid arteries (CCAs; a procedure herein referred to as “CCA occlusion” [CCAO]) in rats was employed in this study. Seven days after the CCAO procedure, the authors performed encephalo-myo-synangiosis (EMS) and injected plasmid(s) into each

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Zhou, Da-Kai, Xi-Wang Yang, Huining Li, Yongbo Yang, Zhen-Jun Zhu, and Na Wu. "Up-Regulation of Long Noncoding RNA CCAL Predicts Poor Patient Prognosis and Promotes Tumor Metastasis in Osteosarcoma." International Journal of Biological Markers 32, no. 1 (2017): 108–12. http://dx.doi.org/10.5301/jbm.5000240.

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Background Long noncoding RNAs (IncRNAs) play essential roles in tumor progression. Aberrant colorectal cancer-associated IncRNA (CCAL) has been found in colorectal cancer. However, the function of IncRNA CCAL in osteosarcoma (OS) remains unclear. Methods Quantitative real-time PCR (qRT-PCR) was performed to measure CCAL expression in OS tissues and adjacent nontumor tissues. The correlation betweent CCAL expression and clinicopathological features and prognosis was also analyzed. In addition, the function of CCAL was further evaluated by cell proliferation, migration and invasion assays. Resu

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Yaftian, Ali, Soheila Mirshekary, and Dessalegn Getie Mihret. "Learning commercial computerised accounting programmes." Accounting Research Journal 30, no. 3 (2017): 312–32. http://dx.doi.org/10.1108/arj-08-2015-0107.

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Purpose Practical accountving skills such as the ability to use commercial computerised accounting programmes (CCAP) is increasingly becoming expected of accounting graduates. To understand the impact of CCAP on learning, this paper aims to examine students’ motivations for and perceptions about learning CCAP in two accounting subjects trialled in an Australian university. Design/methodology/approach A survey of students who completed the course was conducted twice, before training and assessment using CCAP and after completing the CCAP-based learning activity and the associated assessment tas

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Jenks, Scott A., Chungwen Wei, Regina Bugrovsky, et al. "B cell subset composition segments clinically and serologically distinct groups in chronic cutaneous lupus erythematosus." Annals of the Rheumatic Diseases 80, no. 9 (2021): 1190–200. http://dx.doi.org/10.1136/annrheumdis-2021-220349.

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ObjectiveWhile the contribution of B-cells to SLE is well established, its role in chronic cutaneous lupus erythematosus (CCLE) remains unclear. Here, we compare B-cell and serum auto-antibody profiles between patients with systemic lupus erythematosus (SLE), CCLE, and overlap conditions.MethodsB-cells were compared by flow cytometry amongst healthy controls, CCLE without systemic lupus (CCLE+/SLE−) and SLE patients with (SLE+/CCLE+) or without CCLE (SLE+/CCLE−). Serum was analyed for autoreactive 9G4+, anti-double-stranded DNA, anti-chromatin and anti-RNA antibodies by ELISA and for anti-RNA

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Peng, Hao, and Michael M. Neff. "CIRCADIAN CLOCK ASSOCIATED 1 and ATAF2 differentially suppress cytochrome P450-mediated brassinosteroid inactivation." Journal of Experimental Botany 71, no. 3 (2019): 970–85. http://dx.doi.org/10.1093/jxb/erz468.

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Abstract Brassinosteroids (BRs) are a group of steroid hormones regulating plant growth and development. Since BRs do not undergo transport among plant tissues, their metabolism is tightly regulated by transcription factors (TFs) and feedback loops. BAS1 (CYP734A1, formerly CYP72B1) and SOB7 (CYP72C1) are two BR-inactivating cytochrome P450s identified in Arabidopsis thaliana. We previously found that a TF ATAF2 (ANAC081) suppresses BAS1 and SOB7 expression by binding to the Evening Element (EE) and CIRCADIAN CLOCK ASSOCIATED 1 (CCA1)-binding site (CBS) on their promoters. Both the EE and CBS

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Santamarta, Irene, Antonio Rodríguez-García, Rosario Pérez-Redondo, Juan F. Martín, and Paloma Liras. "CcaR Is an Autoregulatory Protein That Binds to the ccaR and cefD-cmcI Promoters of the Cephamycin C-Clavulanic Acid Cluster in Streptomyces clavuligerus." Journal of Bacteriology 184, no. 11 (2002): 3106–13. http://dx.doi.org/10.1128/jb.184.11.3106-3113.2002.

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ABSTRACT The putative regulatory CcaR protein, which is encoded in the β-lactam supercluster of Streptomyces clavuligerus, has been partially purified by ammonium sulfate precipitation and heparin affinity chromatography. In addition, it was expressed in Escherichia coli, purified as a His-tagged recombinant protein (rCcaR), and used to raise anti-rCcaR antibodies. The partially purified CcaR protein from S. clavuligerus was able to bind DNA fragments containing the promoter regions of the ccaR gene itself and the bidirectional cefD-cmcI promoter region. In contrast, CcaR did not bind to DNA f

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Vargas, Sara O., Esther Korpershoek, Harry P. W. Kozakewich, Ronald R. de Krijger, Jonathan A. Fletcher, and Antonio R. Perez-Atayde. "Cytogenetic and p53 Profiles in Congenital Cystic Adenomatoid Malformation: Insights into its Relationship with Pleuropulmonary Blastoma." Pediatric and Developmental Pathology 9, no. 3 (2006): 190–95. http://dx.doi.org/10.2350/06-01-0025.1.

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Congenital cystic adenomatoid malformation (CCAM), a developmental anomaly of lung, shares many features with the pediatric tumor pleuropulmonary blastoma (PPB). Both may show benign epithelium-lined cysts and mesenchymal proliferation, often with skeletal muscle differentiation. Before its recognition as a distinct entity, PPB was described in several reports as “rhabdomyosarcoma arising in CCAM.” Abnormal karyotypes in PPB often show excess material from chromosome 8. It has also been suggested that PPB may harbor p53 mutations. We examined the karyotype and searched for p53 mutations (via i

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Sarkar, Rhitajit, Bibhabasu Hazra, and Nripendranath Mandal. "Hepatoprotective Potential ofCaesalpinia cristaagainst Iron-Overload-Induced Liver Toxicity in Mice." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/896341.

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The present study was carried out to evaluate the ameliorating effect ofCaesalpinia cristaLinn. (CCME) extract on iron-overload-induced liver injury. Iron overload was induced by intraperitoneal administration of iron dextran into mice. CCME attenuated the percentage increase in liver iron and serum ferritin levels when compared to control group. CCME also showed a dose-dependent inhibition of lipid peroxidation, protein oxidation, and liver fibrosis. The serum enzyme markers were found to be less, whereas enhanced levels of liver antioxidant enzymes were detected in CCME-treated group. In pre

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LOI, P. K., S. A. EMMAL, Y. PARK, and N. J. TUBLITZ. "IDENTIFICATION, SEQUENCE AND EXPRESSION OF A CRUSTACEAN CARDIOACTIVE PEPTIDE (CCAP) GENE IN THE MOTHMANDUCA SEXTA." Journal of Experimental Biology 204, no. 16 (2001): 2803–16. http://dx.doi.org/10.1242/jeb.204.16.2803.

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SUMMARYThe crustacean cardioactive peptide (CCAP) gene was isolated from the tobacco hawkmoth Manduca sexta. The gene has an open reading frame of 125 amino acid residues containing a single, complete copy of CCAP. Analysis of the gene structure revealed three introns interrupting the coding region. A comparison of the M. sexta CCAP gene with the Drosophila melanogaster genome database reveals significant similarities in sequence and gene structure.The spatial and temporal expression patterns of the CCAP gene in the M. sexta central nervous system were determined in all major post-embryonic st

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Ishiyama, Ken, Yukio Kondo, Eric D. Wieder, Sijie Lu, and Jeffrey J. Molldrem. "Aberrantly Expressed Neutrophil Elastase (ELA2) Cleaves Cyclin E (CCNE) in the Nucleus and Cytoplasm of Acute Lymphocytic Leukemia Yielding Novel Leukemia-Associated Antigens." Blood 108, no. 11 (2006): 4429. http://dx.doi.org/10.1182/blood.v108.11.4429.4429.

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Abstract We have shown that donor-derived cytotoxic T lymphocytes (CTL) are specific for two HLA-A2-restricted peptides derived from CCNE (CCNE1144–152, ILLDWLMEV and CCNE2144–152, ILLDWLLEV) specifically lyse lymphoid and myeloid leukemia cells that aberrantly express CCNE. The CCNE protein is overexpressed in AML, ALL, and CML, and in solid tumors such as breast, lung, and gastric cancers. Furthermore, five low molecular weight forms (LMWFs) of CCNE, which are constitutively active to promote cell division, are found only in malignant cells, though it is not known how LMWFs are formed in leu

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McMULLIN, Richard Troy, Lindsay L. BENNETT, Owen J. BJORGAN, et al. "Relationships between air pollution, population density, and lichen biodiversity in the Niagara Escarpment World Biosphere Reserve." Lichenologist 48, no. 5 (2016): 593–605. http://dx.doi.org/10.1017/s0024282916000402.

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AbstractThe fragmented ecosystems along the Niagara Escarpment World Biosphere Reserve provide important habitats for biota including lichens. Nonetheless, the Reserve is disturbed by dense human populations and associated air pollution. Here we investigated patterns of lichen diversity within urban and rural sites at three different locations (Niagara, Hamilton, and Owen Sound) along the Niagara Escarpment in Ontario, Canada. Our results indicate that both lichen species richness and community composition are negatively correlated with increasing human population density and air pollution. Ho

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Wu, Yifei, Hui Lin, Weizhao Yin, Sicheng Shao, Sihao Lv, and Yongyou Hu. "Water Quality and Microbial Community Changes in an Urban River after Micro-Nano Bubble Technology in Situ Treatment." Water 11, no. 1 (2019): 66. http://dx.doi.org/10.3390/w11010066.

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Currently, black-odor river has received great attention in China. In this study, the micro-nano bubble technology (MBT) was used to mitigate the water pollution rapidly and continuously by increasing the concentration of dissolved oxygen (DO) in water. During treatment, the concentration of DO increased from 0.60 mg/L to over 5.00 mg/L, and the oxidation reduction potential (ORP) also changed from a negative value to over 100.00 mV after only five days aeration. High throughput pyrosequencing technology was employed to identify the microbial community structure. At genus level, the dominant b

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Mittendorf, Elizabeth, Gheath Alatrash, Na Qiao, et al. "Cellular Uptake of Soluble Neutrophil Elastase Increases Cyclin E (CCNE) Isoform Expression and Significantly Augments Susceptibility of Breast Cancer Cells to Cytolysis by CCNE-Specific Cytotoxic T Lymphocytes." Blood 116, no. 21 (2010): 2090. http://dx.doi.org/10.1182/blood.v116.21.2090.2090.

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Abstract Abstract 2090 We have shown that cytotoxic T lymphocytes (CTL) with specificity for the cyclin E (CCNE) derived HLA-A2-restricted peptide CCNE144-152 (ILLDWLMEV) specifically lyse myeloid and lymphoid leukemia in proportion to CCNE overexpression. Full length (FL) CCNE is also overexpressed in most solid tumors, including breast cancer where it is a poor prognostic factor. In addition, leukemia and many breast cancers express tumor-specific low molecular weight (LMW) isoforms of CCNE that result from post-translational processing of the FL protein. Neutrophil elastase (NE), derived fr

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Patel, Sparsh, Po-Yin Cheung, Tze-Fun Lee, Matteo Pasquin, Megan O’Reilly, and Georg Schmolzer. "USING CHEST COMPRESSIONS WITH ASYNCHRONOUS VENTILATION AT VARIOUS CHEST COMPRESSION RATES (90, 100, 120/MIN) – A RANDOMIZED CONTROLLED ANIMAL TRIAL." Paediatrics & Child Health 23, suppl_1 (2018): e27-e28. http://dx.doi.org/10.1093/pch/pxy054.071.

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Abstract BACKGROUND The current Pediatric Advanced Life Support guidelines recommends that newborns who require cardiopulmonary resuscitation (CPR) in settings (e.g., prehospital, Emergency department, or paediatric intensive care unit, etc.) should receive continuous chest compressions with asynchronous ventilations (CCaV) if an advanced airway is in place. However, this has never been examined in a newborn model of neonatal asphyxia. OBJECTIVES To determine if CCaV at rates of 90/min or 120/min compared to current standard of 100/min will reduce the time to return of spontaneous circulation

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Williams, Michael J., Mehwish Akram, Deimante Barkauskaite, et al. "CCAP regulates feeding behavior via the NPF pathway in Drosophila adults." Proceedings of the National Academy of Sciences 117, no. 13 (2020): 7401–8. http://dx.doi.org/10.1073/pnas.1914037117.

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The intake of macronutrients is crucial for the fitness of any animal and is mainly regulated by peripheral signals to the brain. How the brain receives and translates these peripheral signals or how these interactions lead to changes in feeding behavior is not well-understood. We discovered that 2 crustacean cardioactive peptide (CCAP)-expressing neurons in Drosophila adults regulate feeding behavior and metabolism. Notably, loss of CCAP, or knocking down the CCAP receptor (CCAP-R) in 2 dorsal median neurons, inhibits the release of neuropeptide F (NPF), which regulates feeding behavior. Furt

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Alehaideb, Zeyad, Saleh AlGhamdi, Wesam Bin Yahya, et al. "Anti-Proliferative and Pro-Apoptotic Effects of Calligonum comosum (L’Her.) Methanolic Extract in Human Triple-Negative MDA-MB-231 Breast Cancer Cells." Journal of Evidence-Based Integrative Medicine 25 (January 1, 2020): 2515690X2097839. http://dx.doi.org/10.1177/2515690x20978391.

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Triple-negative breast cancer (TNBC), the most aggressive subtype, does not respond to targeted therapy due to the lack of hormone receptors. There is an urgent need for alternative therapies, including natural product-based anti-cancer drugs, at lower cost. We investigated the impact of a Calligonum comosum L’Hér. methanolic extract (CcME) on the TNBC MDA-MB-231 cell line proliferation and related cell death mechanisms performing cell viability and cytotoxicity assays, flow cytometry to detect apoptosis and cell cycle analysis. The apoptosis-related protein array and cellular reactive oxygen

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Nurhayati, Betty, Ira Gustira Rahayu, Sonny Feisal Rinaldi, et al. "The Antioxidant and Cytotoxic Effects of Cosmos caudatus Ethanolic Extract on Cervical Cancer." Indonesian Biomedical Journal 10, no. 3 (2018): 243–9. http://dx.doi.org/10.18585/inabj.v10i3.441.

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BACKGROUND: Oxidative stress is closely related to all aspects of cancer. Cosmos caudatus ethanolic extract (CCEE) has been proved to have antioxidant effect that inhibited cancer cell growth due to its bioactive compounds such as catechin, quercetin and chlorogenic acid. This study aimed to evaluate antioxidant and anticancer activity of CCEE and its compounds.METHODS: Total phenol was measured according to the Folin-Ciocalteu method. Catechin, quercetin and chlorogenic acid contained in CCEE were identified by high-performance liquid chromatography (HPLC). Antioxidant activity was evaluated

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Blanco-Alvarez, Victor Manuel, Guadalupe Soto-Rodriguez, Juan Antonio Gonzalez-Barrios, et al. "Prophylactic Subacute Administration of Zinc Increases CCL2, CCR2, FGF2, and IGF-1 Expression and Prevents the Long-Term Memory Loss in a Rat Model of Cerebral Hypoxia-Ischemia." Neural Plasticity 2015 (2015): 1–15. http://dx.doi.org/10.1155/2015/375391.

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Prophylactic subacute administration of zinc decreases lipoperoxidation and cell death following a transient cerebral hypoxia-ischemia, thus suggesting neuroprotective and preconditioning effects. Chemokines and growth factors are also involved in the neuroprotective effect in hypoxia-ischemia. We explored whether zinc prevents the cerebral cortex-hippocampus injury through regulation of CCL2, CCR2, FGF2, and IGF-1 expression following a 10 min of common carotid artery occlusion (CCAO). Male rats were grouped as follows: (1) Zn96h, rats injected with ZnCl2(one dose every 24 h during four days)

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Ye, Ying, Yanan Song, Juhua Zhuang, Saifei He, Jing Ni, and Wei Xia. "Long Noncoding RNA CCAL Promotes Papillary Thyroid Cancer Progression by Activation of NOTCH1 Pathway." Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 26, no. 9 (2018): 1383–90. http://dx.doi.org/10.3727/096504018x15188340975709.

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Long noncoding RNA CCAL has been reported to promote tumor progression in various human cancers, including hepatocellular carcinoma, osteosarcoma, and colorectal cancer. However, the role of CCAL in papillary thyroid cancer remains largely unknown. In the present study, we found that the expression of CCAL was upregulated in papillary thyroid tumor tissues compared to adjacent normal tissues. Moreover, the expression of CCAL was positively related with papillary thyroid cancer severity and TNM stage and predicated poor prognosis. Besides, we found that knockdown of CCAL significantly inhibited

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Enggist, Elisabeth, and Linda Thöny-Meyer. "The C-Terminal Flexible Domain of the Heme Chaperone CcmE Is Important but Not Essential for Its Function." Journal of Bacteriology 185, no. 13 (2003): 3821–27. http://dx.doi.org/10.1128/jb.185.13.3821-3827.2003.

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ABSTRACT CcmE is a heme chaperone active in the cytochrome c maturation pathway of Escherichia coli. It first binds heme covalently to strictly conserved histidine H130 and subsequently delivers it to apo-cytochrome c. The recently solved structure of soluble CcmE revealed a compact core consisting of a β-barrel and a flexible C-terminal domain with a short α-helical turn. In order to elucidate the function of this poorly conserved domain, CcmE was truncated stepwise from the C terminus. Removal of all 29 amino acids up to crucial histidine 130 did not abolish heme binding completely. For dete

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Morotti, Raffaella A., Maria C. Gutierrez, Fred Askin, et al. "Expression of Thyroid Transcription Factor-1 in Congenital Cystic Adenomatoid Malformation of the Lung." Pediatric and Developmental Pathology 3, no. 5 (2000): 455–61. http://dx.doi.org/10.1007/s100240010092.

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Congenital cystic adenomatoid malformation (CCAM) is an abnormality of branching morphogenesis of the lung. CCAM types 1, 2, and 3 exhibit a cellular composition that is different from that of CCAM type 4 when evaluated with bronchiolar and alveolar cell markers. Thyroid transcription factor 1 (TTF-1) regulates early lung development. To evaluate the potential role of TTF-1 in the development of CCAM, TTF-1 expression in CCAM was compared to that of fetal lungs at varying gestational ages. Twenty-three CCAM cases (17 type 1, two type 2, two type 3, and two type 4) and 11 fetal lungs (3 pseudog

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Tran, Hoang-Anh, Jessica B. O'Connell, Urie K. Lee, John C. Polanco, Tina I. Chang, and Arthur H. Friedlander. "Relationship between symptomatic lower limb peripheral artery disease and calcified carotid artery plaque detected on panoramic images of neurologically asymptomatic males." Dentomaxillofacial Radiology 48, no. 5 (2019): 20180432. http://dx.doi.org/10.1259/dmfr.20180432.

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Objective: Males with peripheral arterial disease (PAD) are at high risk of ischaemic stroke given that atherogenic risk factors for both diseases are similar. We hypothesized that neurologically asymptomatic males diagnosed with PAD would demonstrate calcified carotid artery plaques (CCAP) on panoramic images (PI) significantly more often than similarly aged males not having PAD. Methods: Investigators implemented a retrospective cross-sectional study. Subjects were male patients over age 50 diagnosed with PAD by ankle-brachial systolic pressure index results of [Formula: see text]0.9. Contro

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Frei, E., C. Visco, Z. Y. Xu-Monette, et al. "Addition of rituximab to chemotherapy overcomes the negative prognostic impact of cyclin E expression in diffuse large B-cell lymphoma." Journal of Clinical Pathology 66, no. 11 (2013): 956–61. http://dx.doi.org/10.1136/jclinpath-2013-201619.

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BackgroundHigh levels of cyclin E (CCNE) are accompanied by shorter survival in cyclophosphamide, hydroxydaunorubicin, oncovin and prednisone (CHOP)-treated diffuse large B-cell lymphomas (DLBCL), independent of the international prognostic index (IPI). Data on the prognostic role of CCNE in the ‘rituximab (R)-era’ are lacking.MethodsTo test reproducibility and applicability of observations from the ‘pre-R era’ to the ‘R era’, we examined the prognostic role of CCNE expression by immunohistochemistry in 1579 DLBCL on tissue microarrays (TMA); 339 patients were treated by CHOP and 635 by R-CHOP

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Klare, Kerstin, John R. Weir, Federica Basilico, et al. "CENP-C is a blueprint for constitutive centromere–associated network assembly within human kinetochores." Journal of Cell Biology 210, no. 1 (2015): 11–22. http://dx.doi.org/10.1083/jcb.201412028.

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Kinetochores are multisubunit complexes that assemble on centromeres to bind spindle microtubules and promote faithful chromosome segregation during cell division. A 16-subunit complex named the constitutive centromere–associated network (CCAN) creates the centromere–kinetochore interface. CENP-C, a CCAN subunit, is crucial for kinetochore assembly because it links centromeres with the microtubule-binding interface of kinetochores. The role of CENP-C in CCAN organization, on the other hand, had been incompletely understood. In this paper, we combined biochemical reconstitution and cellular inv

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Patel, Toral C., Jodie V. Malhotra, and Joseph J. Saseen. "Advancing Pharm. D. Training in Egypt through a Structured Preceptor Development Program." Pharmacy 8, no. 3 (2020): 135. http://dx.doi.org/10.3390/pharmacy8030135.

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The Children’s Cancer Hospital of Egypt (CCHE) and the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences (SSPPS) collaborate to offer a Doctor of Pharmacy (Pharm.D.) degree to international pharmacists holding a bachelor’s degree in pharmacy. The experiential training is provided by CCHE’s clinical pharmacist preceptors at CCHE. Clinical pharmacists at CCHE had prior experience precepting baccalaureate pharmacy students, but not Pharm.D. students when this program commenced. Therefore, the SSPPS faculty provided a live preceptor development program for select CCHE cl

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Rhode, Michael, Tim Richter, Dirk Schroepfer, Anna Maria Manzoni, Mike Schneider, and Guillaume Laplanche. "Welding of high-entropy alloys and compositionally complex alloys—an overview." Welding in the World 65, no. 8 (2021): 1645–59. http://dx.doi.org/10.1007/s40194-021-01110-6.

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AbstractHigh-entropy alloys (HEAs) and compositionally complex alloys (CCAs) represent new classes of materials containing five or more alloying elements (concentration of each element ranging from 5 to 35 at. %). In the present study, HEAs are defined as single-phase solid solutions; CCAs contain at least two phases. The alloy concept of HEAs/CCAs is fundamentally different from most conventional alloys and promises interesting properties for industrial applications (e.g., to overcome the strength-ductility trade-off). To date, little attention has been paid to the weldability of HEAs/CCAs en

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Pabst, D. A., S. A. Rommel, W. A. McLellan, T. M. Williams, and T. K. Rowles. "Thermoregulation of the intra-abdominal testes of the bottlenose dolphin (Tursiops truncatus) during exercise." Journal of Experimental Biology 198, no. 1 (1995): 221–26. http://dx.doi.org/10.1242/jeb.198.1.221.

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Dolphins possess a vascular countercurrent heat exchanger (CCHE) that functions to cool their intra-abdominal testes. Spermatic arteries in the posterior abdomen are juxtaposed to veins returning cooled blood from the surfaces of the dorsal fin and tail flukes. In this study, we investigated the effect of exercise on CCHE function in the bottlenose dolphin. The CCHE flanks a region of the bowel in the posterior abdomen and influences colonic temperatures. A rectal probe housing a linear array of seven copper-constantan thermocouples was designed to measure colonic temperatures simultaneously a

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Gustafsson, N., J. Ahlqvist, U. Näslund, et al. "Associations among Periodontitis, Calcified Carotid Artery Atheromas, and Risk of Myocardial Infarction." Journal of Dental Research 99, no. 1 (2019): 60–68. http://dx.doi.org/10.1177/0022034519885362.

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Cardiovascular disease is a common cause of morbidity and premature mortality. Cardiovascular disease can be prevented when risk factors are identified early. Calcified carotid artery atheromas (CCAAs), detected in panoramic radiographs, and periodontitis have both been associated with increased risk of cardiovascular disease. This case-control study aimed to 1) investigate associations between periodontitis and CCAA detected in panoramic radiographs and 2) determine the risk of future myocardial infarctions due to CCAA combined with periodontitis. We evaluated 1,482 participants (738 cases an

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Souto Queiroz de Lima, Kamilla Rebeca. "Comportamento de busca e uso da informação de universitários indígenas do Campus IV – UFPB." Biblionline 16, no. 3/4 (2021): 96–97. http://dx.doi.org/10.22478/ufpb.1809-4775.2020v16n3/4.57716.

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Nos últimos anos, as políticas públicas de educação no ensino superior têm contribuído para inclusão de indígenas nas universidades. Entretanto, os universitários indígenas como usuários de informação enfrentam dificuldades ao longo da graduação que podem interferir no desenvolvimento acadêmico dos mesmos. O acesso e uso da informação são primordiais para inclusão intelectual e social das classes menos favorecidas, onde a intervenção da Ciência da Informação busca mediar junto aos universitários indígenas na superação de suas lacunas informacionais. Buscando entender como se configura o compor

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So, Anthony K. C., Swan S. W. Cot, and George S. Espie. "Characterization of the C-terminal extension of carboxysomal carbonic anhydrase from Synechocystis sp. PCC6803." Functional Plant Biology 29, no. 3 (2002): 183. http://dx.doi.org/10.1071/pp01179.

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Sequence analysis of the carboxysomal carbonic anhydrase (CcaA) from Synechocystis PCC6803, Synechococcus PCC7942 and Nostoc ATCC29133, indicated high sequence identity to the β class of plant and bacterial carbonic anhydrases (CA), and conservation of the active site region. However, the cyanobacterial enzyme has a C-terminal extension of about 75 amino acids (aa) not found in the plant enzymes, and largely absent from other bacterial enzymes. Using recombinant DNA technology, genes encoding C-terminal truncation products of up to 127 aa were overexpressed in E. coli, and partially purified l

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Elliott, George C. "Imbibition of Water by Rockwool-Peat Container Media Amended with Hydrophilic Gel or Wetting Agent." Journal of the American Society for Horticultural Science 117, no. 5 (1992): 757–61. http://dx.doi.org/10.21273/jashs.117.5.757.

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Water retention at effective water-holding capacity (EWHC) and container capacity (CCAP) were measured in four rockwool-peat potting media amended with a wetting agent and/or a hydrophilic gel in pots 12 cm tall containing 445 cm3 medium, and irrigated by capillary mat, flood-and-drain, trickle emitter, or overhead sprinkler. Water retention was measured by weighing. Irrigation was continued until EWHC (i.e., net water retention when no weight increase could be obtained by further irrigation) was reached. CCAP (i.e., net water retention following saturation and free drainage) was measured at t

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Simon, Eléanor, Sergio Fernández de la Puebla, and Isabel Guerrero. "Drosophila Zic family member odd-paired is needed for adult post-ecdysis maturation." Open Biology 9, no. 12 (2019): 190245. http://dx.doi.org/10.1098/rsob.190245.

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Specific neuropeptides regulate in arthropods the shedding of the old cuticle (ecdysis) followed by maturation of the new cuticle. In Drosophila melanogaster , the last ecdysis occurs at eclosion from the pupal case, with a post-eclosion behavioural sequence that leads to wing extension, cuticle stretching and tanning. These events are highly stereotyped and are controlled by a subset of crustacean cardioactive peptide (CCAP) neurons through the expression of the neuropeptide Bursicon (Burs). We have studied the role of the transcription factor Odd-paired (Opa) during the post-eclosion period.

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