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1

Frederick, Ray Gomez* Lendl Israel Alunan Sherwin Paul Almazan John Martin Jarillas Maria Theresa De Leon Marc Rosales. "CURRENT-MODE INSTRUMENTATION AMPLIFIERS USING 0.25µM CMOS PROCESS FOR ECG SIGNALS." Global Journal of Engineering Science and Research Management 6, no. 2 (2019): 12–18. https://doi.org/10.5281/zenodo.2562032.

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Four monolithic current-mode instrumentation amplifier (in-amp) topologies implemented in a standard 0.25µm complementary metal-oxide semiconductor (CMOS) process, with positive second-generation current conveyors (CCII+) as building blocks are presented in this paper.  The in-amp topologies are designed to handle biomedical signals, specifically that of the electrocardiogram (ECG). Four types of CCII+ are characterized and realized using a rail-to-rail operational amplifier (op-amp) and different types of current mirrors.  The Op-Amp with Simple Current Mirror exhibits the hig
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SALEM, SAMIR BEN, DORRA SELLAMI MASMOUDI, and MOURAD LOULOU. "A NOVEL CCII-BASED TUNABLE INDUCTANCE AND HIGH FREQUENCY CURRENT-MODE BAND PASS FILTER APPLICATION." Journal of Circuits, Systems and Computers 15, no. 06 (2006): 849–60. http://dx.doi.org/10.1142/s0218126606003386.

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In this paper, we introduce an implementation of a CCII-based grounded inductance operating in class AB. In order to get tunable characteristics of the design, a translinear CCII configuration is used as a basic block for its high level of controllability. A frequency characterization of the translinear CCII is done. In order to optimize its static and dynamic characteristics, an algorithmic driven methodology is developed ending to the optimal transistor geometries. The optimized CCII has a current bandwidth of 1.28 GHz and a voltage bandwidth of 5.48 GHz. It is applied in the simulated induc
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3

Cabeza, Rafael, Alfonso Carlosena, and Arie Arbel. "Use of a CCII — as a universal building block." Microelectronics Journal 28, no. 5 (1997): 543–50. http://dx.doi.org/10.1016/s0026-2692(96)00100-0.

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4

SOLIMAN, AHMED M. "HISTORY AND PROGRESS OF THE TOW–THOMAS BIQUADRATIC FILTER PART II: OTRA, CCII, AND DVCC REALIZATIONS." Journal of Circuits, Systems and Computers 17, no. 05 (2008): 797–826. http://dx.doi.org/10.1142/s0218126608004691.

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The realization of the Tow–Thomas (TT) circuit using the Operational Transresistance Amplifier (OTRA) is reviewed. The circuit employs two OTRA, and all passive elements are floating as the original Tow–Thomas circuit. The Current Conveyor (CCII) TT circuits are reviewed next. The progress in the realization of the TT circuit using CCII is demonstrated clearly by summarizing eight different circuits. One of the circuits has the advantage of very high input impedance using all grounded resistors and capacitors. The Differential Voltage Current Conveyor (DVCC) as the active building block in rea
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Scarsella, Massimo, Gianluca Barile, Vincenzo Stornelli, Leila Safari, and Giuseppe Ferri. "A Survey on Current-Mode Interfaces for Bio Signals and Sensors." Sensors 23, no. 6 (2023): 3194. http://dx.doi.org/10.3390/s23063194.

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In this study, a review of second-generation voltage conveyor (VCII) and current conveyor (CCII) circuits for the conditioning of bio signals and sensors is presented. The CCII is the most known current-mode active block, able to overcome some of the limitations of the classical operational amplifier, which provides an output current instead of a voltage. The VCII is nothing more than the dual of the CCII, and for this reason it enjoys almost all the properties of the CCII but also provides an easy-to-read voltage as an output signal. A broad set of solutions for relevant sensors and biosensor
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GHALLAB, YEHYA H., WAEL BADAWY, MOHAMED ABOU EL-ELA, and MOHAMED H. EL-SAID. "THE OPERATIONAL FLOATING CURRENT CONVEYOR AND ITS APPLICATIONS." Journal of Circuits, Systems and Computers 15, no. 03 (2006): 351–72. http://dx.doi.org/10.1142/s0218126606003118.

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A five-port general-purpose analog building block, termed as an Operational Floating Current Conveyor (OFCC), is described. The OFCC combines the features of current feedback operational amplifier, second-generation current conveyor and operational floating conveyor. An implementation scheme of the OFCC is described and its terminal operational characteristics are used to yield a working device. The OFCC is then used as a single block to realize the current conveyors (CCII+ and CCII-) as well as the four basic amplifiers (i.e., voltage, current, transconductance, and transresistance amplifiers
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SHAKTOUR, MAHMOUD AHMED, FATHI OMAR ABUBRIG, and AlAA YOUSEF OKASHA. "A NEW CMOS DESIGN AND ANALYSIS OF CURRENT CONVEYOR SECOND GENERATION (CCII)." مجلة الجامعة الأسمرية: العلوم التطبيقية 2, no. 2 (2017): 55–64. http://dx.doi.org/10.59743/aujas.v2i2.1109.

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This paper describes the current conveyors used as a basic building block in a variety of electronic circuit in instrumentation and communication systems. Today thesesystems are replacing the conventional Op-amp in so many applications such as active filters, analog signal processing. Current conveyors are unity gain active building block having high linearity, wide dynamic range and provide higher gain bandwidthThe proposed current conveyors are simulated using TSMC 0.18μm CMOS technology on Advanced Design System and the results are also tabulated for comparison. The main features of these c
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8

De Marcellis, A., G. Ferri, N. C. Guerrini, G. Scotti, V. Stornelli, and A. Trifiletti. "The VCG-CCII: a novel building block and its application to capacitance multiplication." Analog Integrated Circuits and Signal Processing 58, no. 1 (2008): 55–59. http://dx.doi.org/10.1007/s10470-008-9213-6.

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9

SOLIMAN, AHMED M. "ADJOINT NETWORK THEOREM AND FLOATING ELEMENTS IN THE NAM." Journal of Circuits, Systems and Computers 18, no. 03 (2009): 597–616. http://dx.doi.org/10.1142/s0218126609005307.

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Although the adjoint network theorem preserves all the circuit properties it does not, however, guarantee that the floating property of an element is maintained. In other words, the adjoint of a floating element may not be floating and vice-versa a nonfloating element may have an adjoint floating element as will be explained in this paper. An important and new property of the Nodal Admittance Matrix (NAM) is that it can identify any element as a floating or nonfloating. The four floating basic building blocks including the nullor are tabulated. It is shown that the nullor and the Voltage Mirro
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10

Sharifipoor, Ozra, and Arash Ahmadi. "An analog implementation of biologically plausible neurons using CCII building blocks." Neural Networks 36 (December 2012): 129–35. http://dx.doi.org/10.1016/j.neunet.2012.08.017.

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11

Ritu, Chaudhary*1 &. Sandeep Singh2. "ANALYSIS OF VARIOUS TOPOLOGIES OF FDCCII AND ITS APPLICATIONS." INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY 6, no. 7 (2017): 75–82. https://doi.org/10.5281/zenodo.822978.

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In this paper, various topologies of fully differential second-generation current conveyor (FDCCII) are presented. The proposed blocks are useful in mixed-mode applications where fully differential signal processing is required. The FDCCII combines the advantages of both second-generation current conveyor (CCII) and differential difference amplifier (DDA), which is further utilized to realize Universal Biquad filters. The circuit can operate from low supply voltages down to 1.65 V. The characteristics of the proposed circuits are verified by LTSPICE simulators using TSMC CMOS 0.35-µm technolog
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Soleimani, Hamid, Arash Ahmadi, Mohammad Bavandpour, and Ozra Sharifipoor. "A generalized analog implementation of piecewise linear neuron models using CCII building blocks." Neural Networks 51 (March 2014): 26–38. http://dx.doi.org/10.1016/j.neunet.2013.12.004.

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Soliman, Ahmed M. "The CCII+ and the ICCII as basic building blocks in low-pass filter realizations." International Journal of Circuit Theory and Applications 36, no. 4 (2008): 493–509. http://dx.doi.org/10.1002/cta.442.

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14

Ma, Jun, and Da Ming Wang. "A New Low Complexity Uplink Multiuser MIMO Detecting Algorithm." Applied Mechanics and Materials 380-384 (August 2013): 3866–69. http://dx.doi.org/10.4028/www.scientific.net/amm.380-384.3866.

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In multiuser MIMO uplink communications, it is necessary to design linear schemes that are able to suppress co-channel interferences (CCIs). In this paper, we propose a linear block QR decomposition (BQRD) which transforms the multiuser channel to a block upper triangular structure based on Gram-Schmidt orthonormalization and can obtain more diversity gain than traditional BD. And a optimal ordering criterion is proposed at last to do full study of BQRD scheme. Simulation results show that the BQRD with the optimal ordering proposed achieves much better performance than the non-ordering one.
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15

Šotner, Roman, Josef Slezák, Tomáš Dostál, and Jiří Petržela. "Universal Tunable Current-Mode Biquad Employing Distributed Feedback Structure with MO-CCCII." Journal of Electrical Engineering 61, no. 1 (2010): 52–56. http://dx.doi.org/10.2478/v10187-010-0007-6.

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Universal Tunable Current-Mode Biquad Employing Distributed Feedback Structure with MO-CCCIIOne possible application of the multiple-output electronically-tunable active building block as a universal filter with distributed feedback structure is presented. The suggested structure is less conventional than the well-known state-variable Kerwin-Huelsman-Newcomb but allows the same filter configurations with the similar properties. The major current-mode design approach disadvantage,ie, the necessity of multiple current outputs, is demonstrated. To date even a rather big line of the commercially a
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16

Eke, Uzoamaka A., Katie Wasserstein, Carolyn Susman, et al. "The Performance of a New Multidimensional Frailty Index in Comparison to the Frailty Phenotype to Assess Frailty in People Living with HIV 50 Years of Age and Older in an Urban HIV Clinic." Journal of AIDS and HIV Treatment 7, no. 1 (2025): 27–37. https://doi.org/10.33696/aids.7.058.

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Background: Frailty is increasingly recognized in older people living with HIV (PLWH), but optimal diagnostics are yet to be determined. Frailty indices (FI) represent an accumulation of health deficits shown to correlate better with mortality and adverse effects of aging than the frailty phenotype or chronological age. Methods: This is a retrospective cohort study of frailty assessments in PLWH aged ≥ 50 years in a multidisciplinary urban HIV clinic. Frailty was assessed using Frailty Phenotype (FP) and a new 40-variable clinical composite FI derived from routine clinical and laboratory data
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17

KIM, KYUNG-SAENG, and KWYRO LEE. "LOW-POWER 2D MOTION ESTIMATION ARCHITECTURE WITH COMPLEMENTARY EMBEDDED MEMORY BANKS." Journal of Circuits, Systems and Computers 10, no. 05n06 (2000): 229–37. http://dx.doi.org/10.1142/s0218126600000184.

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This letter describes a motion estimation architecture with complementary access types of memory banks, one for column vector access and the other for row vector access. It handles 2D image very efficiently for full-search block matching algorithm and maximizes a useful data transfer rate by reducing the overhead clocks for extra data reading and alignment. The results show that power saving is improved by using complementary access types of memory banks and amounts to 27.3% when the full-search block matching algorithm is applied for the CCIR-601 format compared to an identical design without
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18

Maheshwari, Sudhanshu, and Deepak Agrawal. "Cascadable and Tunable Analog Building Blocks Using EX-CCCII." Journal of Circuits, Systems and Computers 26, no. 06 (2017): 1750093. http://dx.doi.org/10.1142/s0218126617500931.

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A new cascadable voltage-input, current-output first-order all-pass filter and its applications in second-order filter and oscillator are presented. The proposed circuit employs a single active element namely extra-X current-controlled current conveyor (EX-CCCII) and only a single grounded capacitor. The circuit exhibits high input and high output impedances, so that the filter can be cascaded without additional buffers. The pole frequency is electronically tunable and the circuit requires no component matching constraints. Effects of nonidealities and parasitics are also discussed. As applica
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Tan, Zebin, Yong Zuo, Hongwei Cao, and Jiahao Huang. "Design of Smart Card Chip Reader Based on STM32." Journal of Networking and Telecommunications 2, no. 1 (2020): 7. http://dx.doi.org/10.18282/jnt.v2i1.838.

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<p>This paper designs a smart card chip reader based on STM32, and gives a block diagram of the overall design of the system. It introduces the design of the peripheral hardware circuit of the main control chip STM32F103CBT6 and the RF processing chip THM3070, and the format of data communication between each part and flow chart. The communication between the host computer and the reader adopts the USB CCID protocol, which supports the USB full-speed communication rate of 12Mbps, improves the interrupt response, and overcomes the shortcomings of the traditional serial port-based readers
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20

Said, Lobna A., Ahmed G. Radwan, Ahmed H. Madian, and Ahmed M. Soliman. "Three Fractional-Order-Capacitors-Based Oscillators with Controllable Phase and Frequency." Journal of Circuits, Systems and Computers 26, no. 10 (2017): 1750160. http://dx.doi.org/10.1142/s0218126617501602.

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This paper presents a generalization of six well-known quadrature third-order oscillators into the fractional-order domain. The generalization process involves replacement of three integer-order capacitors with fractional-order ones. The employment of fractional-order capacitors allows a complete tunability of oscillator frequency and phase. The presented oscillators are implemented with three active building blocks which are op-amp, current feedback operational amplifier (CFOA) and second generation current conveyor (CCII). The general state matrix, oscillation frequency and condition are ded
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21

Kajihara, Jun-ichi, Ye Guoji, Kazuo Kato, and Yasuo Suzuki. "Sulfatide, a Specific Sugar Ligand for L-Selectin, Blocks CCI4-induced Liver Inflammation in Rats." Bioscience, Biotechnology, and Biochemistry 59, no. 1 (1995): 155–57. http://dx.doi.org/10.1271/bbb.59.155.

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22

Pandiev, Ivaylo. "Design and Implementation of Self-Limiting Two-Stage LC Oscillators Using Cascade Structure of Monolithic CCIIs as Active Elements." Energies 16, no. 17 (2023): 6226. http://dx.doi.org/10.3390/en16176226.

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This paper presents the structure and principle of operation of two circuit configurations of self-limiting LC oscillators using monolithic positive second-generation current conveyors (CCII+s), that are implemented using Current-Feedback Operational Amplifiers (CFOAs) with an available compensation pin (Z). The proposed LC oscillators are synthesized using a systematic approach in the design of analog electronic circuits and can be considered as variants of the basic three-point oscillators, implemented using transistors (BJTs or FETs). Based on the analysis of the structure and electrical pa
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Thitimahatthanagusol, Phatsagul, Charinsak Saetiaw, Thanaset Thosdeekoraphat, Chanchai Thongsopa, and Saksit Summart. "CCCIIs-Based First-Order All-Pass Filter and Quadrature Oscillators." Journal of Circuits, Systems and Computers 26, no. 06 (2017): 1750094. http://dx.doi.org/10.1142/s0218126617500943.

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This paper introduces a current-mode first-order all-pass filter (APF) and its application in quadrature oscillator (QO) based on CCCII. The proposed filter can provide inverting and noninverting all-pass functions with a same circuit topology, it uses two CCCIIs and one grounded capacitor. Moreover, the first-order all-pass filter was applied in current-mode sinusoidal quadrature oscillators with the design based on block diagrams. The introduced oscillators can provide four phase-quadrature signals which independently control the condition of oscillation (CO) and frequency of oscillation (FO
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Máximo, Cristina, Manuela Lageiro, Ana Duarte, Alberto Reis, and Maria Costa-Ferreira. "Different bioreactor configurations for the decolourisation of the azo dye reactive black 5 byGeotrichumsp. CCMI 1019." Biocatalysis and Biotransformation 22, no. 5-6 (2004): 307–13. http://dx.doi.org/10.1080/10242420400024516.

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Guerard, Emily, Andrew B. Dodge, Jennifer G. Le-Rademacher, et al. "Electronic Geriatric Assessment: Is It Feasible in a Multi-Institutional Study That Included a Notable Proportion of Older African American Patients? (Alliance A171603)." JCO Clinical Cancer Informatics, no. 5 (April 2021): 435–41. http://dx.doi.org/10.1200/cci.20.00163.

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PURPOSE This study determined whether an electronic version of the geriatric assessment is feasible in a multi-institutional, diverse setting. METHODs Ten sites within the Alliance for Clinical Trials in Oncology participated. Patients who had active cancer or a history of cancer and were 65 years of age or older were eligible. The geriatric assessment was completed with an electronic data capture system that had been loaded onto iPads. Feasibility was defined a priori as completion in at least 70% of patients either with or without help. To enhance racial diversity, the original sample size w
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Oliwa, Tomasz, Steven B. Maron, Leah M. Chase, et al. "Obtaining Knowledge in Pathology Reports Through a Natural Language Processing Approach With Classification, Named-Entity Recognition, and Relation-Extraction Heuristics." JCO Clinical Cancer Informatics, no. 3 (December 2019): 1–8. http://dx.doi.org/10.1200/cci.19.00008.

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PURPOSE Robust institutional tumor banks depend on continuous sample curation or else subsequent biopsy or resection specimens are overlooked after initial enrollment. Curation automation is hindered by semistructured free-text clinical pathology notes, which complicate data abstraction. Our motivation is to develop a natural language processing method that dynamically identifies existing pathology specimen elements necessary for locating specimens for future use in a manner that can be re-implemented by other institutions. PATIENTS AND METHODS Pathology reports from patients with gastroesopha
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El-Refai, Sherif M., Joshua D. Brown, Susanne M. Arnold, Esther P. Black, Markos Leggas, and Jeffery C. Talbert. "Epidemiologic Analysis Along the Mevalonate Pathway Reveals Improved Cancer Survival in Patients Who Receive Statins Alone and in Combination With Bisphosphonates." JCO Clinical Cancer Informatics, no. 1 (November 2017): 1–12. http://dx.doi.org/10.1200/cci.17.00010.

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Purpose Cohort studies report associations between statin use and improved survival in patients with cancer. We used pharmacoepidemiologic methods to evaluate the survival of patients with cancer who received statins alone or in ostensibly synergistic drug combinations. Materials and Methods Patients with cancer who were diagnosed from 2010 to 2013 were identified in a large health care claims database. The rate of all-cause death up to 1 year after diagnosis was compared by Cox proportional hazard regression. Sensitivity analyses included age stratification, statin type and intensity, and com
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Shakirov, Z. S., К. S. Mamanazarova, A. G. Sherembetov, and N. S. Azimova. "Antifungal properties of rhizobacterial strains in relation to fungi of agricultural crops." Biosystems Diversity 30, no. 4 (2022): 430–35. http://dx.doi.org/10.15421/012242.

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On earth, pathogenic fungal infections are considered one of the most common crop problems, accounting for more than 80% of all plant diseases. The production of biologics and the fight against pathogens are highly relevant priorities. In this article, rhizosphere cultures isolated from wheat root tubers have been studied in detail for the development of pathogenic fungi. In the course of research, the inhibitory properties of rhizobacteria against common pathogenic fungi were studied. The main mechanism of antagonism is that bacteria directly affect phytopathogens or increase plant resistance
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Pho, Kelvin K., Rong Lu, Samantha Gates, et al. "Mobile Device Applications for Electronic Patient Portals in Oncology." JCO Clinical Cancer Informatics, no. 3 (December 2019): 1–8. http://dx.doi.org/10.1200/cci.18.00094.

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PURPOSE Mobile devices provide individuals with rapid and frequent access to electronic patient portals. We investigated how oncology patients use this technology to review test results and communicate with providers. PATIENTS AND METHODS We performed a retrospective study of patients enrolled in the MyChart electronic health portal associated with the Epic electronic medical record at the Harold C. Simmons Comprehensive Cancer Center from 2012 to 2017. We recorded type of portal access according to year and patient characteristics. Associations among patient characteristics and types of porta
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Holt, Marilyn E., Kathleen F. Mittendorf, Michele LeNoue-Newton, et al. "My Cancer Genome: Coevolution of Precision Oncology and a Molecular Oncology Knowledgebase." JCO Clinical Cancer Informatics, no. 5 (September 2021): 995–1004. http://dx.doi.org/10.1200/cci.21.00084.

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PURPOSE The My Cancer Genome (MCG) knowledgebase and resulting website were launched in 2011 with the purpose of guiding clinicians in the application of genomic testing results for treatment of patients with cancer. Both knowledgebase and website were originally developed using a wiki-style approach that relied on manual evidence curation and synthesis of that evidence into cancer-related biomarker, disease, and pathway pages on the website that summarized the literature for a clinical audience. This approach required significant time investment for each page, which limited website scalabilit
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Wan, Qiuzhen, Jiong Liu, and Simiao Chen. "An Inductorless Gain-Controllable Wideband LNA Based on CCCIIs." Micromachines 13, no. 11 (2022): 1832. http://dx.doi.org/10.3390/mi13111832.

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In this paper, an inductorless and gain-controllable 0.5~2.5 GHz wideband low noise amplifier (LNA) based on second generation current controlled current conveyors (CCCIIs) is presented. The proposed wideband LNA utilizes CCCIIs as building blocks to implement the amplifier stage and impedance matching stage. By varying the DC biasing current of the CCCII, the voltage gain of the proposed LNA is controllable in the range of 1~18 dB. In the frequency range of 0.5~2.5 GHz, the post-layout simulation results show that the proposed LNA has a typical voltage gain S21 of 12.6 dB with a gain ripple o
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Cummings, Cadan, Yuxin Miao, Gabriel Dias Paiao, Shujiang Kang, and Fabián G. Fernández. "Corn Nitrogen Status Diagnosis with an Innovative Multi-Parameter Crop Circle Phenom Sensing System." Remote Sensing 13, no. 3 (2021): 401. http://dx.doi.org/10.3390/rs13030401.

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Accurate and non-destructive in-season crop nitrogen (N) status diagnosis is important for the success of precision N management (PNM). Several active canopy sensors (ACS) with two or three spectral wavebands have been used for this purpose. The Crop Circle Phenom sensor is a new integrated multi-parameter proximal ACS system for in-field plant phenomics with the capability to measure reflectance, structural, and climatic attributes. The objective of this study was to evaluate this multi-parameter Crop Circle Phenom sensing system for in-season diagnosis of corn (Zea mays L.) N status across d
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Peterson, Dylan J., Nicolai P. Ostberg, Douglas W. Blayney, James D. Brooks, and Tina Hernandez-Boussard. "Machine Learning Applied to Electronic Health Records: Identification of Chemotherapy Patients at High Risk for Preventable Emergency Department Visits and Hospital Admissions." JCO Clinical Cancer Informatics, no. 5 (October 2021): 1106–26. http://dx.doi.org/10.1200/cci.21.00116.

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PURPOSE Acute care use (ACU) is a major driver of oncologic costs and is penalized by a Centers for Medicare & Medicaid Services quality measure, OP-35. Targeted interventions reduce preventable ACU; however, identifying which patients might benefit remains challenging. Prior predictive models have made use of a limited subset of the data in the electronic health record (EHR). We aimed to predict risk of preventable ACU after starting chemotherapy using machine learning (ML) algorithms trained on comprehensive EHR data. METHODS Chemotherapy patients treated at an academic institution and a
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Cotner, Cody E., Mohan Balachandran, David Do, et al. "Automated Text-Based Symptom Monitoring With Rapid Clinician Triage for Patients With Cancer and Suspected or Confirmed COVID-19." JCO Clinical Cancer Informatics, no. 5 (October 2021): 1134–40. http://dx.doi.org/10.1200/cci.21.00069.

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PURPOSE Patients with cancer are at greater risk of developing severe symptoms from COVID-19 than the general population. We developed and tested an automated text-based remote symptom-monitoring program to facilitate early detection of worsening symptoms and rapid assessment for patients with cancer and suspected or confirmed COVID-19. METHODS We conducted a feasibility study of Cancer COVID Watch, an automated COVID-19 symptom-monitoring program with oncology nurse practitioner (NP)-led triage among patients with cancer between April 23 and June 30, 2020. Twenty-six patients with cancer and
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Hershman, Dawn L., Cathee Till, Jason D. Wright, Scott Ramsey, William E. Barlow, and Joseph M. Unger. "History of Diabetes and Survival Outcome Among Participants 65 Years or Older in SWOG Clinical Trials." JCO Clinical Cancer Informatics, no. 1 (November 2017): 1–12. http://dx.doi.org/10.1200/cci.17.00040.

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Purpose Diabetes is common, increases with age, and may affect outcomes among people with cancer. Understanding the association between diabetes and cancer outcome is challenging, because patients with diabetes have increased all-cause mortality compared with patients without diabetes. Methods We systematically examined the phase III trial database of SWOG to identify patients enrolled in trials during the period from 1999 to 2011. We linked the SWOG clinical records to Medicare claims data according to Social Security number, sex, and date of birth. Medicare claims were used to identify diabe
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Galsky, Matthew D., Michael Diefenbach, Nihal Mohamed, et al. "Web-Based Tool to Facilitate Shared Decision Making With Regard to Neoadjuvant Chemotherapy Use in Muscle-Invasive Bladder Cancer." JCO Clinical Cancer Informatics, no. 1 (November 2017): 1–12. http://dx.doi.org/10.1200/cci.17.00116.

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Purpose Level 1 evidence supports the use of neoadjuvant chemotherapy (NAC) for the treatment of muscle-invasive bladder cancer (MIBC), but observational data demonstrate that this approach is underused. A barrier to shared decision making is difficulty in predicting and communicating survival estimates after cystectomy with or without NAC. Methods We included patients with MIBC from the National Cancer Database treated with cystectomy. A state-transition model was constructed for calculating 5-year death risk using baseline patient-, tumor-, and facility-level variables. Internal-external cro
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Trask, Peter C., Debanjali Mitra, Shrividya Iyer, Sean D. Candrilli, and James A. Kaye. "Treatment Response Patterns and Related Prognostic Indicators in Chronic Myeloid Leukemia (CML) Patients: A Multi-Country Medical Record Review Study." Blood 118, no. 21 (2011): 3131. http://dx.doi.org/10.1182/blood.v118.21.3131.3131.

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Abstract Abstract 3131 Objective: To assess treatment responses and prognostic indicators of response among patients with chronic myeloid leukemia (CML) in multiple countries. Methods: Physicians in United States (N=60), United Kingdom (N=45), Germany (N=49), and Japan (N=60) were recruited to abstract data retrospectively from medical records of patients diagnosed with CML between 1/1/2005 and 12/31/2009. Patients selected were age ≥18 years and in chronic phase at the time of diagnosis and were Philadelphia chromosome and/or BCR-ABL positive. Patients were also required to have received 1st-
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Romanova, S., E. Krupa, A. Serikova, and S. Alekseev. "MODERN HYDROCHEMICAL CHARACTERISTICS OF WATER BODIES IN THE KAZAKHSTAN PART OF THE BASIN R. IRTYSH." Hydrometeorology and Ecology 112, no. 1 (2024): 121–32. http://dx.doi.org/10.54668/2789-6323-2024-112-1-121-132.

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The article presents materials from our own research on the study of the distribution of the mineralization, ionic composition, hardness, dissolved gases and pH values in various components of the river ecosystem of the Kazakhstan part of the Ertis river basin in the summer of 2023. It has been established that the water of the Black Ertis river is ranked in terms of mineralization to ultra-fresh, the value of total hardness – to soft, the content and ratio of the main ions - to the carbonate class, calcium group, the second type. Within the Pavlodar region, the concentration of the main salt-
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Ohshiro, Kazufumi, Xiyan Xiang, Xiaochun Yang, Krishanu Bhowmick, and Lopa Mishra. "Abstract 5181: SPTBN1D1089Y/+ aggravates liver carcinogenesis via activating SIRT6 and TGF-beta signaling." Cancer Research 85, no. 8_Supplement_1 (2025): 5181. https://doi.org/10.1158/1538-7445.am2025-5181.

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Abstract Background: Obese-driven liver cancer (HCC) is alarmingly rising in the US. Yet, key signaling mechanisms underlying this obesity-driven HCC remain unclear. SIRT6 is a NAD+-dependent deacetylase that limits the activity of the lipogenic transcription factors SREBP1/2 and TGF-β signaling. Reduced SIRT6 is associated with human fatty liver and HCC. We found that TGF-β/SMAD3 signaling pathway and SREBP1/2 are modulated by βII-spectrin (encoded by SPTBN1), and a mutation in human HCC, D1089Y abrogates SMAD3 binding (Gastro 2018; 154:195-210). In stressed hepatocytes, βII-spectrin promotes
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Ressurreição, Sandrine Da, Sónia Pedreiro, Maria Teresa Batista, and Artur Figueirinha. "Effect of Phenolic Compounds from Cymbopogon citratus (DC) Stapf. Leaves on Micellar Solubility of Cholesterol." Molecules 27, no. 21 (2022): 7338. http://dx.doi.org/10.3390/molecules27217338.

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Dyslipidemias are one of the risk factors for cardiovascular diseases, the leading cause of death and hospitalization worldwide. One way to control cholesterol levels is to control the exogenous cholesterol intake in the body. Natural polyphenolic compounds, namely theaflavins from plant extracts such as black tea, showed the ability to inhibit the formation of the micellar structure, essential for the absorption of cholesterol in the intestine. There are several methodologies to determine this effect, many of which are expensive and time-consuming. Due to these facts, the main purposes of thi
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Morini, Andrea, Massimiliano Fabozzi, Magda Zanelli, et al. "Transanal Irrigation in Patients with Low Anterior Resection Syndrome After Rectal-Sphincter-Preserving Surgery for Oncological and Non-Oncological Disease: A Systematic Review." Surgical Techniques Development 13, no. 4 (2024): 409–25. https://doi.org/10.3390/std13040033.

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Background/Objectives: Transanal irrigation (TAI) has been recognized as a safe and effective treatment for neurological bowel dysfunction, chronic constipation or fecal incontinence and has also been proposed for patients with low anterior resection syndrome (LARS). The aim of the present systematic review was to evaluate the feasibility and effectiveness of TAI in patients with significant LARS symptoms. Methods: We performed a systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and guidelines in addition to the Cochrane Ha
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42

Sunil, Kumar Guru, and Behera Rajesh. "Changes in some haematological parameters induced on exposure to a sub-lethal dose of fluoride (NaF) in the freshwater fish, Channa punctatus (BLOCH)." Biolife 3, no. 4 (2022): 778–82. https://doi.org/10.5281/zenodo.7302605.

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<strong>ABSTRACT</strong> Alterations in some haemato-biochemical parameters of a freshwater, air breathing fish, <em>Channa punctatus</em> under the stress of chronic, sub-lethal dose (10ppm) of fluoride (NaF) for 75 days were studied. The TEC, haemoglobin % and PCV steadily and significantly decreased, whereas the TLC was noted to increase significantly with an increase in the duration of exposure time. The MCV, MCH and MCHC decreased significantly with an increase in the exposure period. The plasma protein, lipid and glucose decreased progressively and significantly whereas the plasma chole
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Himansu, Bhusan Mahananda. "Alterations in some haemato-bio-chemical parameters of a fresh water, air breathing fish, Channa punctatus (Bloch) under the stress of chronic, sub-lethal dose of nickel." Biolife 2, no. 4 (2022): 1392–97. https://doi.org/10.5281/zenodo.7238181.

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<strong>ABSTRACT</strong> Alterations in some haemato-bio-chemical parameters of a freshwater, air birthing fish, Chnna punctatus under the stress of chronic, sub-lethal dose (10ppm) of nickel for 60 days were studied. The TEC, haemoglobin% and PCV progressively and significantly decreased, whereas the TLC exhibited a steady and significant increase with an increase in the duration of exposure time. The plasma protein, cholesterol, lipid, glucose and iron decreased steadily and significantly with an increase in the duration of exposure time. But the plasma triglyceride significantly increased
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Surakampontorn, Wanlop, and Khanittha Kaewdang. "Development of Differential Amplifier Based the Second Generation Current Conveyors." ECTI Transactions on Electrical Engineering, Electronics, and Communications 10, no. 2 (2012). http://dx.doi.org/10.37936/ecti-eec.2012102.170345.

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In this article, developments of Second Generation Current Conveyors (CCII) that are realized by based on the use of a differential amplifier (diff-amp) as a circuit building block are reviewed. The basic concepts of current conveyor are firstly outlined. One of the first CMOS-based promising techniques to implement CCII that proposed by Surakampontorn et al. is reviewed [9-11]. The applications of Surakampontorn’s CCII as basic circuit building blocks to realize analog circuits and systems and the modifications methods to provide multiple outputs CCIIs are outlined and discussed. Based on fee
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Athokpam, Bidhanshel Singh, Ashish Ranjan, Sumita Banerjee, Vivek Bhatt, Mamata Maisnam, and Saikat Mukherjee. "Active block EX-CCII based electrical circuit for practical impedance data of OSCC." Analog Integrated Circuits and Signal Processing, July 2, 2024. http://dx.doi.org/10.1007/s10470-024-02273-0.

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Tian, Yi, Qi Mao, wenfeng Wang, and Yan Zhang. "Hierarchical Agent Transformer Network for COVID-19 Infection Segmentation." Biomedical Physics & Engineering Express, February 27, 2025. https://doi.org/10.1088/2057-1976/adbafa.

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Abstract Accurate and timely segmentation of COVID-19 infection regions is critical for effective diagnosis and treatment. While convolutional neural networks (CNNs) exhibit strong performance in medical image segmentation, they face challenges in handling complex lesion morphologies with irregular boundaries. Transformer-based approaches, though demonstrating superior capability in capturing global context, suffer from high computational costs and suboptimal multi-scale feature integration. To address these limitations, we proposed Hierarchical Agent Transformer Network (HATNet), a hierarchic
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Sun, Weiwei, Jungang Chen, Li Yan, Jinzhao Lin, Yu Pang, and Guo Zhang. "COVID-19 CT image segmentation method based on swin transformer." Frontiers in Physiology 13 (August 22, 2022). http://dx.doi.org/10.3389/fphys.2022.981463.

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Owing to its significant contagion and mutation, the new crown pneumonia epidemic has caused more than 520 million infections worldwide and has brought irreversible effects on the society. Computed tomography (CT) images can clearly demonstrate lung lesions of patients. This study used deep learning techniques to assist doctors in the screening and quantitative analysis of this disease. Consequently, this study will help to improve the diagnostic efficiency and reduce the risk of infection. In this study, we propose a new method to improve U-Net for lesion segmentation in the chest CT images o
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Shannon, Kevin. "The CCDI Comes Out of the Starting Block." Journal of Clinical Oncology, June 15, 2023. http://dx.doi.org/10.1200/jco.23.00652.

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Sobande, Francesca, David Hesmondhalgh, and Anamik Saha. "Black, Brown and Asian cultural workers, creativity and activism: The ambivalence of digital self-branding practices." Sociological Review, April 23, 2023, 003802612311639. http://dx.doi.org/10.1177/00380261231163952.

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How do cultural and creative workers respond to racism and the politics of representation and respectability in the digital age? In what ways do they engage in forms of community-building and solidarity-making, while managing pressures to build digital presence and personal brands? This article seeks to address these questions via 30 in-depth interviews with Black, Brown and Asian (BBA) workers in the UK cultural and creative industries (CCIs). Focusing on the ambivalence of digital self-branding practices, our work builds on scholarship on inequalities in the CCIs, and on platformization and
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Alaybeyoglu, E., and F. Ugranli. "Analog Building Blocks Optimization for Low Pass Filter of IEEE 802.11n Wireless LAN: OTA and CCII." IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems, 2020, 1. http://dx.doi.org/10.1109/tcad.2020.3044851.

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