Academic literature on the topic 'CD23'

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Journal articles on the topic "CD23"

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Lones, Mark, and Ivan Kirov. "Cell Surface Targets for Monoclonal Antibody Therapy in Lymphoid Neoplasms of Children and Adolescents." Blood 104, no. 11 (2004): 4544. http://dx.doi.org/10.1182/blood.v104.11.4544.4544.

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Abstract Recently, monoclonal antibodies have become available for treatment of lymphoid neoplasms in adults, but have not been studied in children and adolescents. These monoclonal antibodies are directed against cell surface antigens CD20 (Rituximab, Ibritumomab-Tiuxetan, Tositumomab), CD22 (Epratuzumab), CD52 (CAMPATH-1H), HLA-DR Beta-chain (Hu1D10), CD23 (IDEC-152), and CD33 (Gemtuzumab Ozogamicin). The objective of this study is to identify cell surface targets eligible for monoclonal antibody therapy in lymphoid neoplasms of children and adolescents. This is a retrospective analysis of l
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Geisler, CH, JK Larsen, NE Hansen, et al. "Prognostic importance of flow cytometric immunophenotyping of 540 consecutive patients with B-cell chronic lymphocytic leukemia." Blood 78, no. 7 (1991): 1795–802. http://dx.doi.org/10.1182/blood.v78.7.1795.1795.

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Abstract Blood mononuclear cells from 540 newly diagnosed, unselected patients with B-cell chronic lymphocytic leukemia (CLL) were examined by immunofluorescence flow cytometry for a panel of surface membrane markers, including IgM and IgD, the monoclonal antibodies anti-CD3, -5, -20, -21, -22, -FMC7, and, for the final 125 patients, anti-CD23. There were 503 CD5+ and 37 CD5- cases. In the CD5+ cases, the cells typically expressed IgM, IgD, CD20, CD21, CD22, and CD23. In univariate analysis, age, clinical stage, IgM-fluorescence intensity, CD23, and FMC7 had significant prognostic importance,
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Geisler, CH, JK Larsen, NE Hansen, et al. "Prognostic importance of flow cytometric immunophenotyping of 540 consecutive patients with B-cell chronic lymphocytic leukemia." Blood 78, no. 7 (1991): 1795–802. http://dx.doi.org/10.1182/blood.v78.7.1795.bloodjournal7871795.

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Blood mononuclear cells from 540 newly diagnosed, unselected patients with B-cell chronic lymphocytic leukemia (CLL) were examined by immunofluorescence flow cytometry for a panel of surface membrane markers, including IgM and IgD, the monoclonal antibodies anti-CD3, -5, -20, -21, -22, -FMC7, and, for the final 125 patients, anti-CD23. There were 503 CD5+ and 37 CD5- cases. In the CD5+ cases, the cells typically expressed IgM, IgD, CD20, CD21, CD22, and CD23. In univariate analysis, age, clinical stage, IgM-fluorescence intensity, CD23, and FMC7 had significant prognostic importance, with high
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Escribano, Luis, Alberto Orfao, Jesús Villarrubia, et al. "Immunophenotypic Characterization of Human Bone Marrow Mast Cells. A Flow Cytometric Study of Normal and Pathological Bone Marrow Samples." Analytical Cellular Pathology 16, no. 3 (1998): 151–59. http://dx.doi.org/10.1155/1998/341340.

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The goal of the present paper was to define the immunophenotype of bone marrow mast cells (BMMC) from healthy controls and patients with hematologic malignancies (HM) based on the use of multiple stainings with monoclonal antibodies analyzed by flow cytometry. Our results show that BMMC from both groups of individuals display a similar but heterogenous immunophenotype. The overall numbers of BMMC are higher in the HM group of individuals (p= 0.08). Three patterns of antigen expression were detected: (1) markers constantly positive in all cases analyzed (CD9, CD29, CD33, CD43, CD44, CD49d, CD49
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Polishchuk, Alyona, Michael Zavelevich, and Daniil Gluzman. "VILLOUS LYMPHOCYTES IN BLOOD AND BONE MARROW IN SOME FORMS OF B-CELL LYMPHOID MALIGNANCIES." EUREKA: Life Sciences, no. 5 (September 30, 2020): 29–33. http://dx.doi.org/10.21303/2504-5695.2020.001429.

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The cytological and immunocytochemical features of the lymphocytes with villous morphology in peripheral blood and bone marrow in some B-lymphoproliferative disorders were studied. The diagnosis of hairy cell leukemia, a hairy cell leukemia variant, splenic marginal zone lymphoma and splenic diffuse red pulp small B-cell lymphoma was ascertained in accordance with the new revision of the WHO classification (2016). The neoplastic cells of hairy cell leukemia were determined by the presence of high tartrate resistant acid phosphatase (TRAP) activity. Cell surface expression of CD19, CD20 and CD2
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Galtseva, I. V., Yu A. Tsoy, A. E. Grachev, et al. "Multicolor flow cytometry in the diagnosis of Waldenstrom macroglobulinemia." Oncohematology 20, no. 1 (2025): 128–38. https://doi.org/10.17650/1818-8346-2025-20-1-128-138.

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Waldenstrom macroglobulinemia is a lymphoplasmacytic lymphoma, the morphological substrates of which are b‑lymphocytes, proplasmocytes, and plasma cells. The world Health Organization recommends multicolor flow cytometry with analysis of markers such as IgM, Cd19, Cd20, Cd22, Cd25, Cd10, Cd23, Cd103, Cd138, for diagnosing this disease. Based on international and our own experience, we recommend that tumor b‑lymphocytes and plasma cells be analyzed separately for the diagnosis of waldenstrom macroglobulinemia, since the immunophenotypic profile of these populations differs. In diagnostics, this
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Alyona, Polishchuk, Zavelevich Michael, and Gluzman Daniil. "VILLOUS LYMPHOCYTES IN BLOOD AND BONE MARROW IN SOME FORMS OF B-CELL LYMPHOID MALIGNANCIES." EUREKA: Life Sciences, no. 5 (September 30, 2020): 29–33. https://doi.org/10.21303/2504-5695.2020.001429.

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The cytological and immunocytochemical features of the lymphocytes with villous morphology in peripheral blood and bone marrow in some B-lymphoproliferative disorders were studied. The diagnosis of hairy cell leukemia, a hairy cell leukemia variant, splenic marginal zone lymphoma and splenic diffuse red pulp small B-cell lymphoma was ascertained in accordance with the new revision of the WHO classification (2016). The neoplastic cells of hairy cell leukemia were determined by the presence of high tartrate resistant acid phosphatase (TRAP) activity. Cell surface expression of CD19, CD20 and CD2
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Paiva, Aldair Sousa, Alessandra Suelen Jardim Silva, Victor lima Soares, et al. "Importance of Flow Cytometry in the Differential Diagnosis of Hairy Cell Leukemia in the State of Rio Grande Do Norte, Brazil." Blood 136, Supplement 1 (2020): 14–15. http://dx.doi.org/10.1182/blood-2020-143225.

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Introduction:Hairy Cell Leukemia (HCL) is a B-cell non-Hodgkin's Lymphoma (B-NHL) representing about 2% of chronic leukemias, is manifested in adults with an average age of 55 years old or more and the ratio of male: female is 5:1, being more common among white people. It is characterized by the presence of neoplastic lymphocytes with cytoplasmic projections (villous cells), a characteristic commonly observed in other DLPCs such as variant HCL (HCL-v) and splenic villous cell lymphoma (SVCL), being the immunophenotyping by flow cytometry determinant in the differential diagnosis of these neopl
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Rousset, F., R. W. Malefijt, B. Slierendregt, et al. "Regulation of Fc receptor for IgE (CD23) and class II MHC antigen expression on Burkitt's lymphoma cell lines by human IL-4 and IFN-gamma." Journal of Immunology 140, no. 8 (1988): 2625–32. http://dx.doi.org/10.4049/jimmunol.140.8.2625.

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Abstract The effect of rIL-4 on the expression of low affinity receptor for the Fc part of IgE (Fc epsilon R2/CD23) and class II MHC antigens on Burkitt's lymphoma (BL) cell lines was investigated. Some of the BL lines contained low percentages of CD23 and HLA-DQ-positive cells, but virtually all cells expressed HLA-DR. IL-4 induced CD23 and class II MHC Ag expression on 7 of 9 BL. Optimal CD23 and class II MHC expression was observed after 48-72 h of incubation. Induction of CD23 and class II MHC Ag in the BL cell line BL2 by IL-4 was confirmed at the specific mRNA level. Significant activati
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Matutes, E., R. Morilla, K. Owusu-Ankomah, A. Houlihan, and D. Catovsky. "The immunophenotype of splenic lymphoma with villous lymphocytes and its relevance to the differential diagnosis with other B-cell disorders." Blood 83, no. 6 (1994): 1558–62. http://dx.doi.org/10.1182/blood.v83.6.1558.1558.

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Abstract Splenic lymphoma with villous lymphocytes (SLVL) is a low-grade disorder that regularly presents with peripheral blood involvement. We describe the immunophenotype of the circulating cells from 100 SLVL patients whose disease has been characterized on clinical, morphologic, and histologic grounds. Cells from all cases expressed B-cell antigens (CD19 and CD37) and/or HLA-Dr and showed light chain restriction (kappa/lambda: 1.5/1) with moderate to strong intensity of membrane Ig staining. Cells from most cases (> 80%) were CD24+, FMC7+, and expressed strongly membrane CD22. The monoc
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Dissertations / Theses on the topic "CD23"

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Shi, Jianguo. "Interaction of human CD23 with IgE and CD21." Thesis, King's College London (University of London), 1997. https://kclpure.kcl.ac.uk/portal/en/theses/interaction-of-human-cd23-with-ige-and-cd21(373685f2-b918-4cae-9404-c10d226ff134).html.

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Van, Zyl Dwain George. "Production of recombinant human CD21 and CD23 : towards a better understanding of their interaction." Thesis, Nelson Mandela Metropolitan University, 2013. http://hdl.handle.net/10948/d10211135.

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The prevalence of allergic diseases has dramatically increased over the last three decades. Presently, it is estimated that 20-30 per cent of the developed world suffers from allergic diseases. The majority of allergic diseases are rooted in the activities of IgE; an immunoglobulin which exerts its effector functions by interacting with a network of proteins. This network includes its low affinity receptor CD23. Cross linking of membrane IgE and CD21 by soluble CD23 results in an increase in IgE synthesis. This marks the interaction between CD23 and CD21 as an attractive therapeutic target. Ho
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Karagiannis, Sophia. "The process of endocytosis of CD23." Thesis, King's College London (University of London), 1995. https://kclpure.kcl.ac.uk/portal/en/theses/the-process-of-endocytosis-of-cd23(553202e7-a9c8-444e-b0a5-f7561d1e6297).html.

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Yahya, Mohd Norhakim. "Analysis of the IgE network : inhibition of CD23-mediated IgE upregulation and CD21/C3d interaction." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:bc5ff165-2d2c-4e4f-a0e9-5651cacd2ddf.

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Allergic reactions are mainly mediated by the interactions between the IgE and its ligands, amongst them CD23 and CD21 in what is termed the IgE network. CD23 is involved in upregulating IgE expression by forming a trimolecular complex with CD21 and IgE on the B-cell surface, resulting in the specific activation of IgE-positive B cells. CD21 also interacts with C3d and is a bridge between the innate and the immune system. A crystal structure of the interaction has been solved (Szakonyi et al., 2001) but was controversial because it contradicted previous biochemical analyses. The aims of this t
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Ford, Jill Wallace. "CD23's Role as a Negative Regulator of Allergic Disease: in vivo Effects of Murine CD23 Destabilization and Allelic Mutations." VCU Scholars Compass, 2007. http://hdl.handle.net/10156/2104.

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Ferreira, Lauren. "Cytokine properties of CD23 on human Eosinophilic cells." Thesis, Nelson Mandela Metropolitan University, 2007. http://hdl.handle.net/10948/503.

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CD23, the low affinity IgE receptor, is expressed by various cell types and has numerous functions depending on the form of the protein, its interaction with various ligands and the type of cell involved. CD23 is pivotal in the regulation of IgE, with the soluble form involved in up-regulation, while the membrane bound form is involved in the down-regulation. It is clear why it is believed to be a central molecule in allergic responses, and a therapeutic target for the treatment of allergic disease. In this study a recombinant form of the entire extracellular domain of the protein, exCD23, was
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Grundy, Gabrielle Jane. "The structure and function of human soluble CD23." Thesis, King's College London (University of London), 2001. https://kclpure.kcl.ac.uk/portal/en/theses/the-structure-and-function-of-human-soluble-cd23(1c2f66b1-b335-4192-892f-bbbf3afde432).html.

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Yuan, Daopeng. "Structural studies of human CD23 and its complexes." Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/structural-studies-of-human-cd23-and-its-complexes(b8946602-66b9-4b39-a02e-4cda67c1c26d).html.

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IgE plays a central role in the pathogenesis of immediate hypersensitivity reactions through interacting with its receptors, in particular the high affinity receptor FcεRI. The low-affinity IgE receptor, CD23, affects IgE-dependent immune responses by regulating the synthesis of IgE, facilitating allergen presentation to the immune system, and influencing the activation and differentiation of B- and T-cells. Surprisingly, CD23 is different from other Ig receptors and belongs to the C-type (calcium-dependent) lectin family. Calcium binding to CD23 affects IgE binding to CD23, but previous NMR a
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Ilkow, Veronica Franciszka. "Engineering IgE antibodies and CD23 for therapeutic discovery." Thesis, King's College London (University of London), 2018. https://kclpure.kcl.ac.uk/portal/en/theses/engineering-ige-antibodies-and-cd23-for-therapeutic-discovery(54f73d64-5c16-42c4-9dea-42855873eeb6).html.

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Immunoglobulin E (IgE) is fundamental to the allergic response and the functions of IgE are mediated by its Fc region binding to two receptors, FcεRI and CD23 (FcεRII). The interaction of IgE with other proteins have complicated our investigations of the unique role each receptor plays. To solve this, a small-scale library of IgE-Fc proteins was designed with two key positions, one at each receptor-binding site mutated. The unpredictable allosteric nature of IgE prevents rational engineering approaches, thus the design of a membrane-bound IgE-Fc-GFP-tagged protein allowed for the generation of
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Bansal, Amolak Singh. "The influence of HLA DR on soluble CD23 secretion and serum soluble CD23 as a marker of immune dysregulation in human disease." Thesis, University of Southampton, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266381.

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Books on the topic "CD23"

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Deavin, Andrew James. The heterogeneous nature of CD23. University of Birmingham, 1994.

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Roussou, Euthalia P. Soluble CD23 in connective tissue diseases. University of Birmingham, 1995.

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1953-, Gordon J., ed. CD23--a novel multifunctional regulator of the immune system that binds IgE. Karger, 1991.

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Ghaderi, Abbas Ali. Functional study of the low affinity IgE receptor (Fc[epsilon]RII/CD23) on human B lymphocytes. University of Birmingham, 1990.

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name, No. Ectopeptidases: CD13/aminopeptidase N and CD26/dipeptidylpeptidase IV in medicine and biology. Kluwer Academic/Plenum, 2003.

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Lieping, Chen, ed. The B7-CD28 family molecules. Landes Bioscience/Eurekah.com, 2003.

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Martin, Hildebrandt, ed. Dipeptidyl aminopeptidases in health and disease. Kluwer Academic / Plenum Publishers, 2003.

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Chen, Haoqian. Spatial Organization of CD28 Modulates T-cell Activation. [publisher not identified], 2016.

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Compans, R. W., M. D. Cooper, T. Honjo, et al., eds. CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential. Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/3-540-27702-1.

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Saoulli, Catherine. CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand. National Library of Canada, 1998.

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Book chapters on the topic "CD23"

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Conrad, Daniel H. "CD23." In New Drugs for Asthma, Allergy and COPD. KARGER, 2001. http://dx.doi.org/10.1159/000062190.

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Wang, F., H. Kikutani, S. Tsang, T. Kishimoto, and E. Kieff. "EBNA-2 Transactivation of CD23." In Epstein-Barr Virus and Human Disease • 1990. Humana Press, 1991. http://dx.doi.org/10.1007/978-1-4612-0405-3_5.

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Conrad, D. H. "Structure and function of CD23." In The Immunoglobulin Receptors and their Physiological and Pathological Roles in Immunity. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5018-7_18.

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Sarfati, M., S. Fournier, H. Ishihara, M. Armant, and G. Delespesse. "The CD23 Multifunctional Molecule and its Soluble Fragments (IgE-Binding Factors or Soluble CD23)." In Progress in Immunology Vol. VIII. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-51479-1_61.

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Swendeman, S. L., and D. Thorley-Lawson. "Soluble CD23/BLAST-2 (S-CD23/Blast-2) and Its Role in B Cell Proliferation." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-74006-0_21.

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Peter Rieber, E., Gerti Rank, Ingrid Köhler, and Susanne Krauss. "Membrane Expression of Fc∈RII/CD23 and Release of Soluble CD23 by Follicular Dendritic Cells." In Advances in Experimental Medicine and Biology. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2930-9_66.

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Ozgur, Yasemin, and Leylagul Kaynar. "Immunotherapy in Acute Leukemias." In Immunotherapy in Human Cancers. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359388.6.

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Immunotherapeutic agents have made remarkable progress in the treatment of acute leukemia. CAR T cell therapy, particularly CD19 and BCMA-targeted CAR-T cells, has shown promising results with high response rates and long remission durations. However, these therapies can be challenging to manage and may present serious toxicities, requiring careful monitoring. Despite the challenges in AML CAR-T cell therapy, new approaches targeting CD33, CD123, and other antigens hold potential for effective treatment options in these patients. In ALL, anti-CD19, anti-CD22 agents, and even CAR-T cell therapi
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Yasui, Teruhito, Hiroshi Fujiwara, Masato Kamanaka, et al. "The Roles Of CD40 And CD23 In IgE Regulation." In Advances in Experimental Medicine and Biology. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4615-5855-2_49.

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Yodoi, J., M. Hosoda, Y. Maeda, S. Sato, M. Takami, and T. Kawabe. "FcεR2/CD23: Regulation and Functional Roles in Cell Activation." In Progress in Immunology. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-83755-5_98.

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Waldschmidt, Thomas J., and Lorraine T. Tygrett. "The Low Affinity IgE Fc Receptor (CD23) Participates in B Cell Activation." In Advances in Experimental Medicine and Biology. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3396-2_19.

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Conference papers on the topic "CD23"

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Hardwick, R. Alan, Bruce L. Levine, Carl H. June, et al. "Development of Closed Systems for Ex Vivo Cell Processing: Utility in Cell and Gene Therapy." In ASME 1997 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1997. http://dx.doi.org/10.1115/imece1997-1316.

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Abstract Two examples are described in which cells were processed in a closed sterile fluid path by using custom-designed instruments, plastic bags and tubing sets, and a sterile connection device. In the first example, nucleated blood cells were collected from HIV+ patients. These cells were enriched for CD4+ cells and the CD4+ cells were expanded in the presence of immobilized CD3 and CD28 antibodies. The cells were then concentrated, washed, and re-infused. For the largest batches this resulted in 2.20 × 1010 cells with 86% viability and a CD4+ cell purity ≥ 95%. In two out of three re-infu
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Theodoro, Flávia Cristine M., Luiz Eduardo Nazario Mendes, Lucas de Oliveira Costa, et al. "Estudo de caso: citometria de fluxo no diagnóstico de leucemia de células vilosas." In Resumos do 56º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2024. https://doi.org/10.5327/1516-3180.142s1.12213.

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Objetivo: A leucemia de células vilosas (LCV), também conhecida como hairy cell leukemia (HCL), compreende uma doença linfoproliferativa maligna de células B maduras, clonal, caracterizada pela presença de linfócitos anômalos com projeções citoplasmáticas semelhantes a fios de cabelo. O comportamento clínico dessa doença está relacionado à infiltração da medula óssea (MO), baço, entre outros tecidos linfoides, podendo acometer o sangue periférico (SP). Os achados laboratoriais da LCV compreendem a citopenia periférica e medular com presença de leucopenia, trombocitopenia e anemia na maioria do
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Barreto, BO, DRP Santos, CE Reis, IO Moura, LFA Nery, and CM Araújo. "LEUCEMIA MIELOIDE AGUDA NA INFÂNCIA: RELATO DE CASO." In Resumos do 55º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2023. http://dx.doi.org/10.5327/1516-3180.141s2.7549.

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Objetivo: Relatar o caso de uma criança com leucemia mieloide aguda (LMA). Método: Os dados foram obtidos de um banco de dados sem identificação individual, com dispensa de tramitação do sistema CEP/CONEP (Art.1º, item V, Resolução 510/2016). O exame de imunofenotipagem de células hematopoiéticas, feito com uma amostra de sangue da medula óssea, é fundamental para a conclusão do caso. É um exame de alta complexidade que permite a determinação da linhagem celular com análise da maturação das células. Coletou-se uma amostra de medula óssea de um paciente de 7 anos para exame de imunofenotipagem
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Soares, Rossy-Eric Pereira, Isys Santos Silva, and Silma Regina Ferreira Pereira. "Expressão aberrante de antígenos de células T na leucemia promielocítica aguda: um imunofenótipo raro." In Resumos do 56º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2024. https://doi.org/10.5327/1516-3180.142s1.13405.

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Objetivo: A leucemia promielocítica aguda, em 90% dos casos, apresenta t(15;17)(q22; q12), células com morfologia hipergranular ou hipogranular e perfil imunofenotípico apresentando expressão de mieloperoxidase, CD13 heterogêneo, CD33 homogêneo e negativo para CD34 , CD15 e HLA-DR. A expressão de CD2, CD7 e CD56 também pode ser observada em alguns casos, mas a expressão de CD3 no citoplasma é um evento muito raro. Nosso objetivo aqui foi descrever um caso atípico de leucemia promielocítica aguda com expressão aberrante de marcadores de células T. Conclusão: Nosso relato é de uma mulher de 25 a
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Theodoro, Flavia Cristine Medeiros, Luiz Eduardo Nazario Mendes, Lucas de Oliveira Costa, et al. "Identificação dos casos de doenças linfoproliferativas de células T em pacientes de Natal, Rio Grande do Norte, entre 2020 e 2022." In Resumos do 56º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2024. https://doi.org/10.5327/1516-3180.142s1.12275.

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Objetivo: As doenças linfoproliferativas crônicas (DLPC) pertencem a um grupo de neoplasias linfoides caracterizadas pela expansão monoclonal e pelo acúmulo de linfócitos maduros, podendo ser de células B, T e células natural Killer (NK). As doenças linfoproliferativas crônicas de células T (DLPC-T) são menos frequentes e têm o diagnóstico estabelecido pela detecção de fenótipos aberrantes, tais como alterações da relação CD4/CD8, presença de células T CD4+/CD8+ e ausência de antígenos Pam-T, como CD3 e CD7. A caracterização dessas entidades é, na maioria das vezes, mais difícil quando compara
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Chichkova, Nathalia, Vladimir Fisenko, and Evgenii Gitel. "Asthma and chronic rhinosinusitis: comparative evaluation of IgE plasma level, CD23+ and blood eosinophils." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa663.

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Harris, Sarah, James Woodworth, Julie Ranuio-Kelley, et al. "Abstract LB-305: Soluble CD23 levels increase following lumiliximab dosing in relapsed chronic lymphocytic leukemia patients." In AACR Annual Meeting--Apr 12-16, 2008; San Diego, CA. American Association for Cancer Research, 2008. http://dx.doi.org/10.1158/1538-7445.am2008-lb-305.

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Rana, Seema, and Rajiv Tangri. "Anaplastic large cell lymphoma ALK negative vs. peripheral T cell lymphoma (NOS) - diagnostic dilemma." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685354.

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Middle aged female presented with generalised lymphadenopathy and fever for last one month. Peripheral blood findings were within normal limits. There was no extra nodal involvement. FNAC performed initially from a cervical node suggested possibility of Hodgkin’s lymphoma and a whole node biopsy was performed. Histopathogical examination revealed effaced nodal architecture and a polymorphous population of lymphocytes, plasma cells, neutrophils and scattered large mononuclear cells with prominent nucleolus. An initial panel of CD3, CD20, LCA, CD15, CD30 and PAX5 was performed. The large atypica
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Theodoro, Flavia Cristine Medeiros, Luiz Eduardo Nazario Mendes, Lucas de Oliveira Costa, et al. "A relevância dos marcadores intracelulares no diagnóstico de leucemias agudas por citometria de fluxo." In Resumos do 56º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2024. https://doi.org/10.5327/1516-3180.142s1.13327.

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Objetivo: A citometria de fluxo é uma ferramenta crucial para diagnóstico em leucemias agudas, usando marcadores intracelulares específicos. Entre esses, a mieloperoxidase (MPO) e cCD13 identificam linhagens mieloides, enquanto cCD79a e cCD22 identificam linhagens linfoides B, e cCD3, linhagens linfoides T. A Transferase Terminal Deoxinucleotidil (TdT) é um marcador valioso para células precursoras linfoides e para o diagnóstico de leucemia/linfoma linfoblástico agudo. Este estudo visou demonstrar a importância desses marcadores no diagnóstico diferencial de leucemias agudas. Método: Foram uti
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Santos, Diego Rodrigues Pena dos, Lídia Freire Abdalla Nery, Cyra Mesquita de Araujo, Bruno Oliveira Barreto, and Isabela de Oliveira Moura. "Leucemia linfoblástica B: relato de caso de paciente masculino de 62 anos atendido em um laboratório de análises clínicas em Uberaba, Minas Gerais." In Resumos do 56º Congresso Brasileiro de Patologia Clínica/Medicina Laboratorial. Zeppelini Editorial e Comunicação, 2024. https://doi.org/10.5327/1516-3180.142s1.10422.

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Objetivo: As leucemias agudas são neoplasias de células precursoras linfo-hematopoiéticas que resultam no acúmulo de precursores mieloides ou linfoides primitivos na medula óssea, no sangue e em outros tecidos. As leucemias linfoblásticas agudas são classificadas na categoria de neoplasias de linhagem B ou T. As leucemias linfoblásticas agudas do tipo B são classificadas em pró-B, B comum, pré-B, B madura, de acordo com o grau de maturação da célula. O objetivo dest studo foi relatar o caso de um paciente do sexo masculino, 62 anos, com leucemia linfoblástica B. Método: Foram obtidos de um ban
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Reports on the topic "CD23"

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Mekova, Ralitsa V., Spaska S. Lesichkova, Adelina D. Tsakova, Julieta Z. Bakalova, Deniz Bakalov, and Mihail Boyanov. Circulating CD3(+)CD4(+)CD28(‒) T Lymphocytes in Patients with Autoimmune Thyroiditis. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2020. http://dx.doi.org/10.7546/crabs.2020.05.14.

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Fitzgerald, David. Anti-CDR3 Therapy for B-Cell Malignancies. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada590597.

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Fitzgerald, David. Anti-CDR3 Therapy for B-Cell Malignancies. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada619137.

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Zheng, Pan. CD24 as a Potential Therapeutic Target in Prostate Cancer. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada508268.

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Shelley, Carl S. Determination of the Molecular Mechanisms Responsible for Abnormal CD43 Expression in Breast Cancer. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada396321.

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Wu, Xin. The efficacy and safety of anti-CD20 antibody treatments in relapsing multiple sclerosis: a systematic review and network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.6.0075.

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Review question / Objective: The objectives of this systematic review were to evaluate the efficacy and safety of the three existing anti-CD20 antibodies for the treatment of relapsing multiple sclerosis and to aid clinicians in choosing medications. Eligibility criteria: We set the inclusion criteria as follows: (1) study type: RCT; (2) language restriction: only available in English; (3) participants: patients ≥18 years of age diagnosed with relapsing MS, whether with a relapsing–remitting course or a secondary progressive course; (4) intervention: anti-CD20 antibody treatments including ocr
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Lin, Zhijuan, Xing Chen, Long Liu, Zhifeng Li, and Bing Xu. Chemo-Free Treatments in Relapsed and/or Refractory Follicular Lymphoma: A Network Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.11.0111.

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Review question / Objective: FL is the most common indolent B cell lymphoma worldwide and patients with FL always have long term survival. However, advanced FL remains incurable and there is no universal agreement on optimal regimen to manage relapsed FL. Condition being studied: The efficacy of chemo-free regimens, including CD20 antibodies and targeted agents, in relapsed and/or refractory Follicular lymphoma. Information sources: We used the MEDLINE, Embase, and Cochrane Library databases to search the RCTs met our selection criteria. We also searched clinicalTrials.gov and the internationa
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Palaga, Tanapat, Nattiya Hirankarn, and Hathaipat Phuwapirom. Level of IL-17 in Thai SLE patients. Chulalongkorn University, 2009. https://doi.org/10.58837/chula.res.2009.30.

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Systemic Lupus Erythematosus (SLE) is an autoimmune disorder which affects various systems. Currently, the etiology of this disease has not been fully elucidated. One of potential causes which may play an important role is the defects in cytokine network and the functions of T lymphocytes. Previously, it was reported that SLE patients showed elevated elevated level of various cytokines such as IL-1β IL-6 IL-23. The aim of this study was to investigate the level of cytokine IL-17 which could be produced by various cell types including T lymphocytes CD4+ T lymphocytes mainly producing IL-17 form
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