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Dissertations / Theses on the topic 'CD52 antigen'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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1

Taylor, Vanessa Claire. "Biology of the CD52 antigen, a major glycoprotein of human lymphocytes." Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242883.

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2

Rowan, Wendy Caroline. "Characterisation of function and regulation of the CD52 antigen on T and B lymphocytes." Thesis, Imperial College London, 1999. http://hdl.handle.net/10044/1/7566.

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3

Shao, Ning. "SYNTHETIC STUDIES OF GLYCOPEPTIDES AND GLYCOCONJUGATES." Case Western Reserve University School of Graduate Studies / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=case1105557527.

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4

Navenot, Jean-Marc. "Diagnostic et suivi biologique de l'hemoglobinurie nocturne paroxystique : contribution a l'etude de la physiopathologie." Nantes, 1996. http://www.theses.fr/1996NANT15VS.

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5

Otipoby, Kevin L. "CD22 regulates B cell fate via two signaling domains within its cytoplasmic tail /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/8335.

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6

Haas, Karen Marie. "Induction and regulation of bovine B lymphocyte responses /." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9999290.

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7

Brown, Marion Hanbury. "Physical interactions of the CD2 antigen." Thesis, Open University, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277634.

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8

Haas, Karen M. "Induction and regulation of bovine B lymphocyte responses." free to MU campus, to others for purchase, 2000. http://wwwlib.umi.com/cr/mo/fullcit?p9999290.

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9

Klein, Jörg. "Verwendung von Gene-Targeting-Techniken zur Etablierung neuer Mauslinien mit Mutationen in B-Zell-Signalwegen." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=976107953.

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10

Mischke, Dirk. "Generierung regulatorischer T-Zellen aus naiven CD4+-CD45RA+-T-Zellen durch Anti-CD4-Interaktion." Berlin wvb, Wiss. Verl, 2007. http://www.wvberlin.de/data/inhalt/mischke_dirk.html.

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11

Suzuki-Jaecks, Ivy. "Fas ligand-mediated costimulation in peripheral T lymphocytes /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/8319.

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12

Krishnan, Ammu Kutty Chandrika. "The CD2 antigen as a target for immunosuppression." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309852.

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13

Lundin, Jeanette. "Targeted CD52 therapy in lymphoid malignancies : a clinical and immunological study /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-441-0/.

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14

Davies, Alexandra. "CD59 antigen, a novel inhibitor of the complement membrane attack complex." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385380.

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15

Schmitz, Paul. "Mechanismen immunologischer Toleranz nach Lebertransplantation : Untersuchungen zum Zytokinmuster intrahepatischer CD4+ CD45RCpos und CD4+ CD45RCneg T-Lymphozyten." Doctoral thesis, kostenfrei, 2007. http://nbn-resolving.de/urn/resolver.pl?urn=nbn:de:bvb:20-opus-26703.

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16

Law, Deborah Ann. "The role of the CD2 antigen in T-lymphocyte interactions." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236192.

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17

Gerlach, Judith. "Der inhibitorische Einfluss von CD22 auf das B-Zellrezeptor-Signal nach Stimulation der B-Zelle." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=970413645.

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18

Secker, Stuart John. "A study of the molecular requirements for CD22-mediated inhibition of antigen receptor signalling." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624231.

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19

Tomlinson, Michael Graham. "Structure and function of the leukocyte and surface antigens CD53 and CD37." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.308502.

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20

Axtell, Robert C. "The role of CD5 in experimental autoimmune encephalitomyelitis." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2007. http://www.mhsl.uab.edu/dt/2007p/axtell.pdf.

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21

Arévalo, Suárez Fernando, Sabino Portugal, Carlos Barreda, et al. "Enfermedad celíaca vs. atrofia villositaria serológicamente negativa: similitudes y diferencias histológicas y en el perfil inmunohistoquímico de linfocitos CD3, CD4, CD8 y CD56." Sociedad de Gastroenterología del Perú (SGP), 2016. http://hdl.handle.net/10757/617280.

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Existe un grupo de enteropatía conocidas como AVSN que pueden simular enfermedad celíaca. Objetivo: El objetivo de este estudio es describir los hallazgos histológicos y de inmunohistoquímica en pacientes con enfermedad celíaca y AVSN. Material y métodos: 15 biopsias de pacientes con enfermedad celíaca y 19 biopsias con AVSN fueron reexaminados. Se estudió características histológicas tales como atrofia severa, hiperplasia de criptas, número de células plasmáticas, número de eosinófilos y presencia de neutrófilos. Asimismo, a través de inmunohistoquímica se estudió la presencia de linfocitos C

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22

Nishimura, Eiji. "Induction of antigen-specific immunologic tolerance by in vivo and in vitro antigen-specific expansion of naturally arising Foxp3[+]CD25[+]CD4[+] regulatory T cells." Kyoto University, 2004. http://hdl.handle.net/2433/145292.

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23

Reinhardt, Julia. "Multidimensional assessment of heterogeneity of human CD4+CD25+ T cells in health and Type 1 Diabetes." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-234017.

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Background Regulatory T cells (Treg) are a subpopulation of CD4+ T cells that play an important role in the peripheral tolerance mechanisms of the immune system. Their suppressive function on autoreactive T cells can prevent autoimmunity. In type 1 diabetes (T1D), Treg have been inconsistently reported to be impaired in their capability to suppress autoreactive T cells (Tan, et al., 2014; Zhang, et al., 2012). Treg can be thymus derived (tTreg) or generated from naïve CD4+ CD25- T cells in the periphery (pTreg), which exhibit similar suppressive qualities as tTreg. They have also been reported

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24

Barreau, Nathalie. "Etude des anticorps anti-gal et anti-hla en xenotransplantation (doctorat : immunologie)." Nantes, 2000. http://www.theses.fr/2000NANT04VS.

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25

Writer, Michele. "Molecular analysis of the recognition of the tumour associated antigen CD55 by the mouse monoclonal antibody 791T/36." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342476.

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26

Marguti, Ivo. "Efeito das células dendríticas na geração de células T CD4+CD25+Foxp3+." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-18102007-154828/.

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As células dendríticas (DCs) são as principais células apresentadoras de antígeno do sistema imune. No entanto, trabalhos têm demonstrado seu envolvimento na manutenção da tolerância imunológica. As células T CD4+CD25+Foxp3+ possuem a capacidade de suprimir respostas imunes. Neste estudo avaliamos as alterações ocorridas na população de células T CD4+CD25+Foxp3+ após co-cultura de células de linfonodo com DCs. Nossos resultados demonstram que após a co-cultura há um aumento da população de células CD4+CD25+Foxp3+ de maneira independente do estado de ativação das DCs ou da presença de antígenos

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27

Vilà, de las Heras Josep M. "Cinasas intracelulares y señalización mediada por CD5." Doctoral thesis, Universitat de Barcelona, 2001. http://hdl.handle.net/10803/853.

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El receptor linfocitario CD5 es una glicoproteína monomérica de membrana de 67KDa. Funcionalmente, es una molécula accesoria, implicada en la modulación de los procesos de activación y diferenciación mediados por el receptor antigénico en células T y B. Su región citoplasmática no contiene ninguna actividad catalítica intrínseca, pero en cambio presenta diversos motivos potenciales de fosforilación para serin/treonin y tirosincinasas, y otros motivos estructurales compatibles con una función señalizadora intracelular. Se ha demostrado que esta región se encuentra constitutivamente fosforilada

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28

Shao, Mei. "Optimize the generation and depletion of alloreactive T cells for cellular therapy." Columbus, Ohio : Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1135261379.

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29

Heitz-Calatayud, Sabine. "Traitement des fausses couches spontanées à répétition par les immunoglobulines intraveineuses : études immunologiques et rôle potentiel des grands lymphocytes granuleux déciduaux." Lyon 1, 1997. http://www.theses.fr/1997LYO1T234.

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30

Hu, Jian. "L'etude de la regulation de l'activation de clones de lymphocytes t humains helpers et cytotoxiques par les molecules cd2." Paris 7, 1988. http://www.theses.fr/1988PA077078.

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31

Leprince, Corinne. "Regulation de la fonction des lymphocytes b humains : interactions entre proteines membranaires et facteurs solubles." Paris 6, 1988. http://www.theses.fr/1988PA066361.

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Etude de la regulation de la reponse immune due aux lymphocytes b a travers leur sensibilite a des signaux regulateurs solubles (interleukines et facteurs bcgf) et l'expression de deux molecules de surface, les antigenes cd5 et b8. 7

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32

Aichelin, Katharina [Verfasser], and Peter [Akademischer Betreuer] Angel. "Development of a CD22-specific chimeric antigen receptor (CAR) for the adoptive T cell therapy of leukemia and lymphoma / Katharina Aichelin ; Betreuer: Peter Angel." Heidelberg : Universitätsbibliothek Heidelberg, 2020. http://d-nb.info/1211090434/34.

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33

Leroy, Elisabeth. "Etude de la signification fonctionnelle des lymphocytes t cd8+/cd57+ après greffe de moelle osseuse allogènique chez l'homme." Paris 7, 1991. http://www.theses.fr/1991PA077054.

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Les lymphocytes de certains receveurs d'une moelle osseuse allogènique, testés à long terme, exercent une fonction suppressive sur la production d'immunoglobulines induite in vitro par le pokeweed mitogen. Les cellules responsables de ce phénomène sont de petits lymphocytes t de forte densité, portant les marqueurs cd8 et cd57 mais non pas les marqueurs d'activation cd25 et hla-dr. Les lymphocytes t cd8, cd57 positifs sont également capables de supprimer la prolifération de lymphocytes du sang périphérique induite par le pokeweed mitogen mais non pas par les antigènes spécifiques. En fait, sti

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34

Allory, Yves. "Expression dans le rein humain de la molécule d'adhérence cellulaire L1CAM : marqueur en pathologie tumorale et non tumorale, et épitope HNK-1." Paris 6, 2005. http://www.theses.fr/2005PA066178.

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35

Yeh, Ming-Hsin. "Identification of CD8+ T cell-stimulating shared antigens that are uncovered in CT26 vaccinated mice in the absence of CD25+ regulatory T cells." Thesis, University of Southampton, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431953.

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36

Simões, Inês Tadeu dos Anjos. "Characterization of the in vivo immunomodulatory properties of CD5 and CD6." Doctoral thesis, Universitat de Barcelona, 2017. http://hdl.handle.net/10803/593499.

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Our goal in this doctoral thesis was to study the immunomodulatory effects of CD5 and CD6, two proteins expressed on the lymphocytes membrane. These two proteins belong to the Scavenger Receptors Cystein- Rich superfamily, characterized by the presence of one or more cysteine rich domains. The interaction between CD6 and ALCAM, its principal ligand, is well established but recently more ligands of CD6 have been described. On the other hand, to date there is no consensus about the CD5 ligand/s, although several candidates have been proposed. Previous work carried out with CD5 and CD6-deficient

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37

Weber, Erich. "Biochemical, immunological and functional characterization of the human small cell lung cancer related cell surface antigens cluster-1 (N-CAM CD56), cluster-4 (CD24) and cluster-5/5A /." [S.l.] : [s.n.], 1994. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=10735.

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38

Benghiat, Fleur. "Contrôle de la réaction allogénique par les lymphocytes T régulateurs naturels." Doctoral thesis, Universite Libre de Bruxelles, 2007. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/216587.

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Le polymorphisme et le polygénisme des complexes majeurs d’histocompatibilité (CMH) limitent les succès de la transplantation. En effet, les disparités, tant d’antigènes mineurs que majeurs, exposent le patient transplanté au risque de rejet et imposent l’administration d’un traitement immunosuppresseur. Ce dernier affecte de façon non spécifique l’ensemble des réponses immunitaires et augmente le risque d’infections mortelles et de cancers. En outre, ce traitement ne semble pas prévenir le rejet chronique. <p>Des découvertes récentes ont confirmé l’existence de lymphocytes appelés régulateurs

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39

Buquet-Fagot, Christine. "Régulation de la prolifération cellulaire et de l'expression génique liée à la phase G1 du cycle de la division cellulaire." Paris 11, 1994. http://www.theses.fr/1994PA11T001.

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40

Mejías, Luque Raquel. "Regulatory effects of pro-inflammatory cytokines on genes associated with gastric carcinogenesis." Doctoral thesis, Universitat Pompeu Fabra, 2009. http://hdl.handle.net/10803/7156.

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El patró específic d'expressió de glicosiltransferases i antígens Lewis observat a la mucosa gàstrica normal es perd durant el procés de la carcinogènesi gàstrica. Aquí descrivim que canvis en l'expressió dels antígens Lewis en cèl·lules HT-29/M3 de càncer de còlon induïts per la transfecció del cDNA de FUT1 resulten en un fenotip menys invasiu i menys metastàtic.<br/>La gastritis crònica produïda per la infecció per Helicobacter pylori és un dels principals determinants en la patogènesi del càncer gàstric, i comporta nivells elevats de citoquines proinflamatòries com TNF-α, IL-1β o

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41

Aubrit, Françoise. "Étude de la molécule E2, produit du gène pseudoautosomal MIC2 et de son rôle dans les phénomènes d'adhésion cellulaire." Compiègne, 1990. http://www.theses.fr/1990COMPD253.

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A l'aide de 4 anticorps monoclonaux sélectionnés pour leur capacité à bloquer la formation des rosettes spontanées entre cellules T humaines et érythrocytes, nous avons montré qu'une molécule différente de CD2 présente à la surface de la cellule T, participe aussi au phénomène des rosettes. Cette molécule que nous avons appelé E2 est détectée aussi bien à la surface des cellules T que des monocytes ou des cellules non hématologiques. E2 est une glycoprotéine de 32 kDa qui possède uniquement des chaînes oligosaccharidiques de types 0-liées, représentant la moitié de son poids moléculaire appare

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42

Berger, Cédric. "Relation entre les Escherichia coli exprimant les adhésines Afa/Dr et les cellules de l'hôte : rôle des rafts lipidiques et des molécules d'adhésion cellulaire reliées à l'antigène carcino-embryonnaire (CEACAM) dans la pathogenèse de l'infection." Paris 11, 2005. http://www.theses.fr/2005PA114818.

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Les E. Coli d'adhésion diffuse (DAEC) sont impliqués dans les infections urinaires et dans les diarrhées. Le seul facteur de virulence identifié est une famille d'adhésines, Afa/Dr, liant le Decay Accelerating Factor (DAF) et le Carcinoembryonic Antigen (CEA) qui appartient à la famille des CEACAM. Notre objectif a été d'étudier les interactions entre les CEACAMs et les DAEC Afa/Dr. Nous avons montré que le le CEACAM1 et le CEACAM6 sont des récepteurs pour les DAEC Afa/Dr et sont recrutés autour des bactéries comme le GM1 et la cavéoline, marqueurs de rafts lipidiques. L'adhésion aux DAF, CEA

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43

Danzer, Claus-Peter. "Generierung von chimären Mäusen mit Mutationen in der Signalleitungs-Domäne von CD22 und Untersuchungen zur Funktion von CD22 in Knockout-Mäusen." Doctoral thesis, 2002. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-4966.

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Gegenstand dieser Arbeit ist die Untersuchung von Aspekten der Funktion von CD22, einem B-Zell spezifischen Transmembran-Rezeptor der Siglec-Familie (Sialinsäure-bindende Immunglobulin-ähnliche Lectine). Mit der äußersten der 7 extrazellulären Ig-ähnlichen Domänen kann CD22 spezifisch mit a2,6-Sialinsäure interagieren. In der cytoplasmatischen Domäne von CD22 befinden sich 6 konservierte Tyrosine, 3 davon in ITIMs (Immunrezeptor tyrosinhaltige inhibitorischen Motiven). Nach Kreuzvernetzung des B-Zell Rezeptors wird CD22 tyrosinphosphoryliert. Die cytosolische Tyrosin-Phosphatase SHP-1 bindet i

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44

Klein, Jörg. "Verwendung von Gene-Targeting-Techniken zur Etablierung neuer Mauslinien mit Mutationen in B-Zell-Signalwegen." Doctoral thesis, 2005. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-13615.

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Das Hauptthema der hier vorliegenden Arbeit befaßt sich mit dem B-Zell spezifischen Oberflächenprotein CD22, einem Mitglied der Siglec (Sialinsäure bindende Igähnliche Lektine) Proteinfamilie. Dieses Transmembranprotein besitzt sieben extrazelluläre Immunoglobulin-ähnliche Domänen und kann über die äußerste V-set Domäne seine Liganden: α2,6 verknüpfte Sialinsäuren binden. CD22 hat eine Transmembrandomäne und eine cytoplasmatische Domäne mit sechs potentiellen Tyrosin Phosphorylierungsstellen, von denen drei eine ITIM-Sequenz (engl. immunoreceptor tyrosine-based inhibitory motif) aufweisen

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45

Gerlach, Judith. "Der inhibitorische Einfluss von CD22 auf das B-Zellrezeptorsignal nach Stimulation der B-Zelle." Doctoral thesis, 2003. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-7207.

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CD22 ist ein B-zellspezifisches Transmembranprotein der Immunglobulin (Ig)-Superfamilie. Es übernimmt zwei unterschiedliche Aufgaben. Zum einen hat CD22 eine inhibitorische Wirkung auf das BZR-Signal. Nach BZR-Ligation lagert sich die Tyrosin-Phosphatase SHP-1 an die cytoplasmatische Domäne von CD22 an, wodurch SHP-1 aktiviert wird. Durch die dephosphorylierende Aktivität der Phosphatase moduliert sie das BZR-Signal. Zum anderen ist CD22 ein Adhäsionsmolekül, das in die Gruppe der Siglecs (Sialic acid-binding Ig-like lectin) gehört. Die N-terminale Ig-Domäne von CD22 weist die Bindungseigensch

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46

Cunha, Ana Margarida Delindro Ferreira da. "Study of CDC5 and CDC6 expression on human iNKT cells." Master's thesis, 2018. http://hdl.handle.net/10773/25182.

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Invariant Natural Killer (iNKT) cells are T lymphocytes that recognize lipid antigens presented by CD1d molecules and have a semi-invariant T cell receptor. iNKT cells produce high quantities of cytokines after antigen recognition or activation. The regulation of iNKT cell activation is crucial for its role in infection and tumor control. CD5 and CD6 are transmembrane surface glycoproteins expressed by conventional T cells that regulate the activation of these cells, but their expression on human iNKTs has not been investigated yet. Here, we studied the basal expression of both CD5 and CD6 on

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47

Procházková, Irena. "Detekce exprese antigenu CD56 u pacientů s morfologickým nálezem LGL v periferní krvi." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-322168.

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Author: Bc. Irena Procházková Job title: Detekce exprese antigenu CD56 u pacientů s morfologickým nálezem LGL v periferní krvi Diploma work Charles Univerzity in Prague, Faculty of Pharmacy in Hradec Králové, Biological and medical department Field of study: Expert of specialized methods Abstract The goal of this diploma work was gathering evidence to support the theory, that LGL cells, large granular lymphocytes, are identical to the population of NK cells, that are detectable by antigen CD56. Numbers of the CD56+ cells were gained by flow cytometry measuring the expression of antigen CD56 la

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48

Reinhardt, Julia. "Multidimensional assessment of heterogeneity of human CD4+CD25+ T cells in health and Type 1 Diabetes." Doctoral thesis, 2017. https://tud.qucosa.de/id/qucosa%3A30854.

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Background Regulatory T cells (Treg) are a subpopulation of CD4+ T cells that play an important role in the peripheral tolerance mechanisms of the immune system. Their suppressive function on autoreactive T cells can prevent autoimmunity. In type 1 diabetes (T1D), Treg have been inconsistently reported to be impaired in their capability to suppress autoreactive T cells (Tan, et al., 2014; Zhang, et al., 2012). Treg can be thymus derived (tTreg) or generated from naïve CD4+ CD25- T cells in the periphery (pTreg), which exhibit similar suppressive qualities as tTreg. They have also been reported

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49

Kohl, Sonja. "Immunzytologische Auswertung zur CD19- und CD56-Antigen-Expression bei Patienten mit Plasmozytom, benigner monoklonaler Gammopathie und reaktiven Plasmazellvermehrungen." 2005. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=014732260&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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50

Limaye, Nisha. "Common alleles of the SLAM/CD2 family are associated with murine lupus." 2005. http://edissertations.library.swmed.edu/pdf/LimayeN042905/LimayeNisha.pdf.

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