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1

Ford, Megan. The role and mechanism of B6/1pr TCR[alpha beta]+CD4-CD8- T cells in immune response regulation. Ottawa: National Library of Canada, 2001.

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2

Kay, Lyndsey Sara. Anti-B-cell lymphoma activity mediated by CD3+CD4-CD8- T cells activated in vitro or in vivo. Ottawa: National Library of Canada, 2003.

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3

G, Janossy, Autran B, Miedema F, Commission of the European Communities., European Federation of AIDS Research., and Medical Research Council (Great Britain), eds. Immunodeficiency in HIV infection and AIDS. Basel: Karger, 1992.

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4

Littman, Dan R., ed. The CD4 Molecule. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-79798-9.

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5

Bunce, Campbell. CD45 isoform expression and CD4 T cell memory. Manchester: University of Manchester, 1996.

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6

Flynn, Sarah. Regulation of CD4 T cell differentiation by OX40L. Birmingham: University of Birmingham, 1999.

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7

George, Sophia Heather L. Effect on HIV-Tat on human hemotopoietic (CD34+) stem cell differentiation. Sudbury, Ont: Laurentian University, Department of Biology, 2001.

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8

Randle, Eliot James. Analysis of CDC4 function during the cell cycle of budding yeast. Manchester: University of Manchester, 1995.

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9

Na, Songqing, and Chandrasekar Venkataraman Iyer. Effector CD4+ T cells in health and disease 2007. Kerala, India: Transworld Research Network, 2007.

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10

McDonagh, Mark Christian. An investigation of CD8 T lymphocyte development and function. Manchester: University of Manchester, 1994.

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11

Compans, R. W., M. D. Cooper, T. Honjo, H. Koprowski, F. Melchers, M. B. A. Oldstone, S. Olsnes, et al., eds. CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential. Berlin, Heidelberg: Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/3-540-27702-1.

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12

Bonneau, Angélique M. HIV-1 Tat: Its effects on CD34+ hematopoietic human stem cell differentiation and survival. Sudbury, Ont: Laurentian University, School of Graduate Studies, 2003.

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13

Owh, Phillip. Myelin basic protein up-regulates CD44 levels in an astrocytoma cell line in vitro. Ottawa: National Library of Canada, 1996.

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14

Roger, Knowles. Better by design?: A contractor's guide to the JCT standard form of buildingcontract with contractor's design (CD81). Knutsford: Knowles, 1990.

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15

Aversa, Franco, Nicolaus M. Kröger, and J. Anguita Velasco. Selected CD34+ stem cells for graft engineering: 34 case reports in hematopoietic stem cell transplantation, October, 2014. Stuttgart: Georg Thieme Verlag, 2015.

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16

David, Chappell, and Smith Mark, eds. Better by design?: A contractor's guide to the JCT standard form of building contract with contractor's design (CD81). 2nd ed. Knutsford: Knowles Publications, 1994.

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17

Meding, Sally Joanna. CD4(plus) T cell effector mechanisms in the protective immune response to Plasmodium chabaudi chabaudi. Uxbridge: Brunel University, 1991.

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18

Cheng, Gordon W. Functions of CD45 in TCR signaling in CD4p+sCD8p+s double-positive thymocytes. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1999.

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19

Rahelu, Manjit. Characterisation of human CD4[superior plus] cytolytic T lymphocytes, with special reference to mycobacterial antigens. Birmingham: University of Birmingham, 1992.

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20

Paiwand, Frouz Frozan. RHAMM, CD44 expression and erk activation are linked in malignant human breast cancer cells and are associated with cell motility. Ottawa: National Library of Canada, 1999.

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21

Khan, Qasim. Regulation of apoptosis in CD4p-sCD8p-s gasgbsp+s T cells. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1999.

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22

Wills, Georgina Anne. An examination of psychological minimisation and mediating personality variables in theinterpretation of CD4 cell counts by HIV positive men. Manchester: University of Manchester, 1996.

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23

Workshop on Mechanisms and Specificity of HIV Entry into Host Cells (1989 San Francisco, Calif.). Mechanisms and specificity of HIV entry into host cells. New York: Plenum Press, 1991.

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24

Koh, Dow-Rhoon. The role of CD4+, CD8+ and CD4-8-T cells in murine experimental allergic encephalomyelitis and lupus. 1993.

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25

Young, Kevin J. The role and mechanisms of CD3+CD4-CD8-regulatory T cells in the suppression of allogeneic immune responses. 2003.

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26

Bhargava, Ashish, and Pranatharthi H. Chandrasekar. Idiopathic CD4+ Lymphocytopenia. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199938568.003.0057.

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These case studies illustrate infections encountered in hospitals among patients with compromised immune systems. As a result of immunocompromise, the patients are vulnerable to common and uncommon infections. These cases are carefully chosen to reflect the most frequently encountered infections in the patient population, with an emphasis on illustrations and lucid presentations to explain state-of-the-art approaches in diagnosis and treatment. Common and uncommon presentations of infections are presented while the rare ones are not emphasized. The cases are written and edited by clinicians and experts in the field. Each of these cases highlight the immune dysfunction that uniquely predisposed the patient to the specific infection, and the cases deal with infections in the cancer patient, infections in the solid organ transplant recipient, infections in the stem cell recipient, infections in patients who receive immunosuppressive drugs, and infections in patients with immunocompromise that is caused by miscellaneous conditions.
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27

S, Jack Robert, ed. CD14 in the inflammatory response. Basel: Karger, 2000.

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28

Jack, R. S., ed. CD14 in the Inflammatory Response. S. Karger AG, 1999. http://dx.doi.org/10.1159/isbn.978-3-318-00463-2.

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29

Kilbey, Liz. Friends 2 Class CD4. Longman, 2003.

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30

Rahemtulla, Aminmohamed. Targeted-disruption of the CD4 gene to study the role of CD4 in T cell development. 1994.

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31

Lakshman, Minalini. CD44 is anti-apoptotic in the murine colonic epithelium. 2006.

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32

Nguyen, Thuy-Linh Thi. CD8+ cytotoxic T lymphocyte tolerance and immunity. 2002.

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33

Jack, Robert S., ed. Cd14 In The Inflammatory Response (CHEMICAL IMMUNOLOGY (FORMERLY PROGRESS ALLERGY)). Karger, 2000.

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34

Durchflusszytometrische Analyse Cd34-Exprimierender Hamatopoetischer Zellen in Blut Und Zytaphereseprodukten. S Karger Pub, 1996.

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35

Bonnard, Madeleine. Novel roles for CD4 in T cell activation. 1999.

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36

Wilson, John W., and Lynn L. Estes. Antiretroviral Therapy for HIV Infection. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199797783.003.0134.

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• Obtain confirmatory human immunodeficiency virus (HIV) testing by rapid test or enzyme-linked immunosorbent assay (ELISA); optimally repeat HIV viral load (VL) and CD4 T-cell (CD4) count 2 times before initiation of therapy; a substantial change in CD4 count is generally >30%• Perform VL immediately before treatment initiation (or change in therapy) and again 2–8 weeks later; for the latter, the optimal decrease would be at least 1 log...
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37

Littman, D. R. Cd4 Molecule: Roles in T Lymphocytes & in HIV Disease. Edited by D. R. Littman. SPRINGER-VERLAG, 1996.

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38

The Cd4 Molecule Current Topics in Microbiology and Immmunology. Springer, 2012.

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39

Girgrah, Nigel. Characterization of surface antigen CD44 on astrocytes in normal and diseased brain. 1993.

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40

Kyewski, B., and Elisabeth Suri-Payer. CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential. Springer, 2010.

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41

McKisic, Maureen Denise. Characterization of ova-reactive and alloreactive CD4+ T cell subsets. 1992.

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42

Ghaffar-Sedeh, Maryam. The role of CD8+ T cell recognition pathways in platelet alloimmunity. 2004.

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43

National AIDS Control Organization (India), ed. Guidelines for collection, handling, and transport of specimens for CD4 testing. [New Delhi]: National AIDS Control Organisation, Ministry of Health and Family Welfare, 2007.

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44

Guidelines for collection, handling and transport of specimens for CD4 testing. [New Delhi]: National AIDS Control Organisation, 2007.

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45

Rangachari, Manu, Nathalie Arbour, Steven M. Kerfoot, and Jorge I. Alvarez, eds. Lymphocytes in MS and EAE: More than just a CD4+ World. Frontiers Media SA, 2017. http://dx.doi.org/10.3389/978-2-88945-302-3.

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46

National AIDS Control Organization (India), ed. Guidelines for collection, handling, and transport of specimens for CD4 testing. [New Delhi]: National AIDS Control Organisation, Ministry of Health and Family Welfare, 2007.

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47

Hartigan-O’Connor, Dennis J., and Christian Brander. Immunology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190493097.003.0005.

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The key factor in HIV pathogenesis is the decline in CD4+ T cells with resultant immunodeficiency and chronic inflammation. Depletion of CD4+ T cells from the gastrointestinal mucosa followed by microbial translocation and subsequent immune activation are components of disease progression in untreated patients. Symptomatic and occult opportunistic infections including cytomegalovirus contribute to chronic inflammation in persons infected with HIV. Antiretroviral therapy (ART) results in immune reconstitution, with increases in peripheral CD4+ T cell lymphocytes in most persons infected with HIV, although immune recovery is quite variable. A subset of patients with AIDS will develop immune reconstitution inflammatory syndromes after initiation of ART. Approximately 1% of persons with HIV are able to control infection without the need for ART (“elite” controllers). A variety of immune-based therapies, including hydroxyurea, growth hormone, and statins, are being studied in clinical trials and may ultimately play a role in treating persons with HIV infection.
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48

Jankovic, Dragana, and Carl G. Feng, eds. CD4+ T cell differentiation in infection: amendments to the Th1/Th2 axiom. Frontiers Media SA, 2015. http://dx.doi.org/10.3389/978-2-88919-565-7.

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49

(Editor), Hari G. Garg, and Charles A. Hales (Editor), eds. Chemistry and Biology of Hyaluronan. Elsevier Science, 2004.

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50

(Editor), Hari G. Garg, and Charles A. Hales (Editor), eds. Chemistry and Biology of Hyaluronan. Elsevier Science, 2004.

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