Relevant bibliographies by topics / CDA

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  2. Dissertations / Theses
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  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'CDA'

Author: Grafiati
Published: 4 June 2021
Last updated: 10 March 2023

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Journal articles on the topic "CDA"

1

Juliusson, G., R. Lenkei, and J. Liliemark. "Flow cytometry of blood and bone marrow cells from patients with hairy cell leukemia: phenotype of hairy cells and lymphocyte subsets after treatment with 2-chlorodeoxyadenosine." Blood 83, no. 12 (June 15, 1994): 3672–81. http://dx.doi.org/10.1182/blood.v83.12.3672.3672.

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Abstract By flow cytometry and an extensive set of markers, we characterized leukemic cells from the blood and bone marrow of 68 symptomatic patients with hairy cell leukemia (HCL). Hairy cells identified in the large cell gate always expressed CD19, CD20, HLA-DR, CD45RA, and B-ly 7. Other markers were occasionally expressed, such as CD38, CD45RO, CD23, CD15, CD4, CD5, and CD10 (expressed on more than 20% of the hairy cells in 44%, 25%, 21%, 18%, 12%, 10%, and 5% of evaluated cases, respectively). During treatment with 2-chlorodeoxyadenosine (CdA), the median lymphocyte counts decreased from 2,000/microL to 300/microL. Flow cytometry was repeated at the nadir (n = 24) of lymphocyte counts, at 3 months (n = 46), at 6 months (n = 50), at 1 year (n = 39), and at 2 years (n = 12) after treatment. The initial decrease of CD8+ and CD20+ cells was greater than that of CD4+ and natural killer (NK) cells, leading to an increasing CD4/CD8 ratio. Median nadir values of CD4+, CD8+, CD20+, and NK cells were 128/microL, 78/microL, 10/microL, and 13/microL, respectively. The subsequent recovery was quicker for CD8+ and NK cells, leading to a normalization within 3 months, whereas CD20+ and CD4+ cells required 1 or 2 years to enter the normal range. The CD4/CD8 ratio thus decreased after the nadir and remained less than 1. CD45RA+ CD4 cells and CD45RA+/CD45RO+ double-positive cells were less affected by CdA. Activated T cells, ie, HLA-DR+ cells, rarely decreased below the normal range and often recovered with an overshoot. CD10+ cells increased in the bone marrow posttreatment as an indication of normal B-cell regeneration in 16 of 36 (44%) patients. The quick regeneration of certain lymphoid subsets might explain the lack of late infections in CdA-treated HCL patients.
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2

Juliusson, G., R. Lenkei, and J. Liliemark. "Flow cytometry of blood and bone marrow cells from patients with hairy cell leukemia: phenotype of hairy cells and lymphocyte subsets after treatment with 2-chlorodeoxyadenosine." Blood 83, no. 12 (June 15, 1994): 3672–81. http://dx.doi.org/10.1182/blood.v83.12.3672.bloodjournal83123672.

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By flow cytometry and an extensive set of markers, we characterized leukemic cells from the blood and bone marrow of 68 symptomatic patients with hairy cell leukemia (HCL). Hairy cells identified in the large cell gate always expressed CD19, CD20, HLA-DR, CD45RA, and B-ly 7. Other markers were occasionally expressed, such as CD38, CD45RO, CD23, CD15, CD4, CD5, and CD10 (expressed on more than 20% of the hairy cells in 44%, 25%, 21%, 18%, 12%, 10%, and 5% of evaluated cases, respectively). During treatment with 2-chlorodeoxyadenosine (CdA), the median lymphocyte counts decreased from 2,000/microL to 300/microL. Flow cytometry was repeated at the nadir (n = 24) of lymphocyte counts, at 3 months (n = 46), at 6 months (n = 50), at 1 year (n = 39), and at 2 years (n = 12) after treatment. The initial decrease of CD8+ and CD20+ cells was greater than that of CD4+ and natural killer (NK) cells, leading to an increasing CD4/CD8 ratio. Median nadir values of CD4+, CD8+, CD20+, and NK cells were 128/microL, 78/microL, 10/microL, and 13/microL, respectively. The subsequent recovery was quicker for CD8+ and NK cells, leading to a normalization within 3 months, whereas CD20+ and CD4+ cells required 1 or 2 years to enter the normal range. The CD4/CD8 ratio thus decreased after the nadir and remained less than 1. CD45RA+ CD4 cells and CD45RA+/CD45RO+ double-positive cells were less affected by CdA. Activated T cells, ie, HLA-DR+ cells, rarely decreased below the normal range and often recovered with an overshoot. CD10+ cells increased in the bone marrow posttreatment as an indication of normal B-cell regeneration in 16 of 36 (44%) patients. The quick regeneration of certain lymphoid subsets might explain the lack of late infections in CdA-treated HCL patients.
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3

Chatila, T. A., and R. S. Geha. "Phosphorylation of T cell membrane proteins by activators of protein kinase C." Journal of Immunology 140, no. 12 (June 15, 1988): 4308–14. http://dx.doi.org/10.4049/jimmunol.140.12.4308.

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Abstract Activation of the enzyme protein kinase C (PKC) plays an important role in T cell activation. We investigated the phosphorylation of CD2, CD3, CD4, CD5, CD7, CD8, CD28 (Tp44), CD43 (sialophorin, gp115), and LFA-1 after incubation of human PBMC with the (PKC) activator PMA. These proteins were chosen for their role in transmembrane signal transduction (CD2, CD3, CD5, CD28, CD43), cell-cell interaction and adhesion (CD2, CD4, CD8, and LFA-1), or involvement in immunodeficiency states (CD43, CD7). CD5, CD7, CD43, and the alpha-chain of LFA-1 were found to be constitutively phosphorylated. PMA induced rapid hyperphosphorylation of CD5, CD7, and CD43, but not of the LFA-1 alpha-chain, and induced the phosphorylation of CD3, CD4, CD8 and of the LFA-1 beta-chain. PMA did not cause the phosphorylation of CD2 and CD28. PMA-induced phosphorylation was partially inhibited by the PKC inhibitor 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine dihydrochloride. Finally, the T cell activator Con A, which binds to the CD3/TCR complex was shown to induce a profile of protein phosphorylation similar to that observed with PMA. We conclude that PKC-mediated phosphorylation of T cell Ag may represent an important regulatory mechanism that governs the process of T cell activation.
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Raimondi, SC, FG Behm, PK Roberson, CH Pui, GK Rivera, SB Murphy, and DL Williams. "Cytogenetics of childhood T-cell leukemia." Blood 72, no. 5 (November 1, 1988): 1560–66. http://dx.doi.org/10.1182/blood.v72.5.1560.1560.

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Abstract The karyotypes of 57 cases of childhood T-cell acute lymphoblastic leukemia (ALL) were analyzed to establish the cytogenetic profile in this disease. Three questions were of particular interest. Do the chromosomal changes in T-cell ALL preferentially affect bands where genes encoding the T-cell receptor for antigen (TCR) have been mapped? Do alterations involving the TCR gene regions appear with any notable frequency in B-progenitor ALL? Do chromosomal abnormalities in this disease relate to stage of T-cell ontogeny? A relatively high proportion of cases (65%) had a pseudodiploid karyotype at presentation, the majority (58%) characterized by a translocation. The overall frequency of translocations was 44%, comparable to that among all banded cases of ALL seen in our laboratory. Hypodiploidy and hyperdiploidy were exceedingly rare (only four of 57 cases); 16 cases (28%) had apparently normal karyotypes. In half the cases with a translocation (14 of 24), the breakpoints were in regions to which the alpha and beta chain TCR genes have been mapped. Chromosomal breakpoints that were consistently observed in the vicinity of TCR gene loci were 7q32-q36 (TCR beta chain; n = 8), 14q11-q13 (TCR alpha chain; n = 6); other frequent breakpoints were 9p13-pter (n = 8) and 6q15-qter (n = 9). Chromosomal alterations occurred near TCR gene loci significantly more often in T-cell cases than in a comparison group of 335 patients with B-cell precursor ALL (26% v 1.5%, P = .0001). Stage I thymocyte development (CD7+, CD2+, CD5+, CD1-, CD3-, CD4-, CD8-) was noted in 23 cases, stage II (CD7+, CD2+, CD5+, CD1+, CD3-, CD4 +/-, CD8 +/-) in 25 cases, and stage III (CD9+, CD2+, CD1-, CD5+, CD3+, and either CD4+ or CD8+) in nine cases. The only statistically significant associations between cytogenetic findings and T-cell ontogeny were a higher frequency of normal karyotypes in cases with stage I thymocytes, and of pseudodiploidy in stage II cases. There was no apparent relationship between particular translocations and level of thymocyte maturation. Our findings indicate that most children with T-cell ALL have pseudodiploid karyotypes, although a surprisingly high percentage lack demonstrable abnormal clones. Specific chromosomal changes do not appear to be related to discrete stages of T-cell ontogeny as defined in this study, but they occur preferentially in bands containing TCR genes.
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Raimondi, SC, FG Behm, PK Roberson, CH Pui, GK Rivera, SB Murphy, and DL Williams. "Cytogenetics of childhood T-cell leukemia." Blood 72, no. 5 (November 1, 1988): 1560–66. http://dx.doi.org/10.1182/blood.v72.5.1560.bloodjournal7251560.

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The karyotypes of 57 cases of childhood T-cell acute lymphoblastic leukemia (ALL) were analyzed to establish the cytogenetic profile in this disease. Three questions were of particular interest. Do the chromosomal changes in T-cell ALL preferentially affect bands where genes encoding the T-cell receptor for antigen (TCR) have been mapped? Do alterations involving the TCR gene regions appear with any notable frequency in B-progenitor ALL? Do chromosomal abnormalities in this disease relate to stage of T-cell ontogeny? A relatively high proportion of cases (65%) had a pseudodiploid karyotype at presentation, the majority (58%) characterized by a translocation. The overall frequency of translocations was 44%, comparable to that among all banded cases of ALL seen in our laboratory. Hypodiploidy and hyperdiploidy were exceedingly rare (only four of 57 cases); 16 cases (28%) had apparently normal karyotypes. In half the cases with a translocation (14 of 24), the breakpoints were in regions to which the alpha and beta chain TCR genes have been mapped. Chromosomal breakpoints that were consistently observed in the vicinity of TCR gene loci were 7q32-q36 (TCR beta chain; n = 8), 14q11-q13 (TCR alpha chain; n = 6); other frequent breakpoints were 9p13-pter (n = 8) and 6q15-qter (n = 9). Chromosomal alterations occurred near TCR gene loci significantly more often in T-cell cases than in a comparison group of 335 patients with B-cell precursor ALL (26% v 1.5%, P = .0001). Stage I thymocyte development (CD7+, CD2+, CD5+, CD1-, CD3-, CD4-, CD8-) was noted in 23 cases, stage II (CD7+, CD2+, CD5+, CD1+, CD3-, CD4 +/-, CD8 +/-) in 25 cases, and stage III (CD9+, CD2+, CD1-, CD5+, CD3+, and either CD4+ or CD8+) in nine cases. The only statistically significant associations between cytogenetic findings and T-cell ontogeny were a higher frequency of normal karyotypes in cases with stage I thymocytes, and of pseudodiploidy in stage II cases. There was no apparent relationship between particular translocations and level of thymocyte maturation. Our findings indicate that most children with T-cell ALL have pseudodiploid karyotypes, although a surprisingly high percentage lack demonstrable abnormal clones. Specific chromosomal changes do not appear to be related to discrete stages of T-cell ontogeny as defined in this study, but they occur preferentially in bands containing TCR genes.
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Barber, Kirk. "CDA Summer Highlights." Journal of Cutaneous Medicine and Surgery 23, no. 1 (January 2019): 18–19. http://dx.doi.org/10.1177/1203475418822495.

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Peng, Yanhong, Yaping Wang, Xiaoyan Liu, Ronghua Zhou, Xianqing Liao, Yong Min, Lixin Ma, Ying Wang, and Ben Rao. "Expression and Surface Display of an Acidic Cold-Active Chitosanase in Pichia pastoris Using Multi-Copy Expression and High-Density Cultivation." Molecules 27, no. 3 (January 26, 2022): 800. http://dx.doi.org/10.3390/molecules27030800.

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Chitosanase hydrolyzes β-(1,4)-linked glycosidic bonds are used in chitosan chains to release oligosaccharide mixtures. Here, we cloned and expressed a cold-adapted chitosanase (CDA, Genbank: MW094131) using multi-copy expression plasmids (CDA1/2/3/4) in Pichia pastoris. We identified elevated CDA expression levels in multi-copy strains, with strain PCDA4 selected for high-density fermentation and enzyme-activity studies. The high-density fermentation approach generated a CDA yield of 20014.8 U/mL, with temperature and pH optimization experiments revealing the highest CDA activity at 20 °C and 5.0, respectively. CDA was stable at 10 °C and 20 °C. Thus, CDA could be used at low temperatures. CDA was then displayed on P. pastoris using multi-copy expression plasmids. Then, multi-copy strains were constructed and labelled as PCDA(1-3)-AGα1. Further studies showed that the expression of CDA(1-3)-AGα1 in multi-copy strains was increased, and that strain PCDA3-AGα1 was chosen for high-density fermentation and enzyme activity studies. By using a multi-copy expression and high-density fermentation approach, we observed CDA-AGα1 expression yields of 102415 U/g dry cell weight. These data showed that the displayed CDA exhibited improved thermostability and was more stable over wider temperature and pH ranges than free CDA. In addition, displayed CDA could be reused. Thus, the data showed that displaying enzymes on P. pastoris may have applications in industrial settings.
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Amalia, Fatya Alty, Arie Indra Gunawan, and Nono Wibisono. "Citra Destinasi Wisata Halal di Jepang: Wisatawan Dan Non-Wisatawan Muslim Dari Indonesia." Jurnal Bisnis dan Kewirausahaan 17, no. 1 (April 6, 2021): 1–10. http://dx.doi.org/10.31940/jbk.v17i1.2473.

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Wisata halal merupakan salah satu sektor bisnis halal yang masih berkembang karena banyaknya potensi wisatawan yang masih dapat dimanfaatkan lebih lanjut. Sebagai seorang wisatawan yang memiliki beberapa pilihan destinasi wisata halal, proses pengambilan keputusannya mengenai destinasi yang dipilih dapat sangat dipengaruhi oleh citra destinasi pada atribut wisata halal di destinasi tersebut. Penelitian ini bertujuan untuk mengkaji citra destinasi wisata halal di Jepang dari wisatawan dan non-wisatawan muslim Indonesia. Untuk pendataan dilakukan survey online (Mei-Juni 2020) terhadap umat Islam Indonesia dan menghasilkan 263 respon valid. Berdasarkan 12 atribut, 263 tanggapan tersebut dianalisis menggunakan uji Mann-Whitney U dan dilanjutkan untuk menguji ukuran efeknya. Hasil penelitian menunjukkan bahwa terdapat 3 dari 12 atribut (CD1, CD4, dan CD10) yang tidak berbeda nyata antara kelompok wisatawan dan non-wisatawan. Sedangkan atribut sisanya berbeda nyata antara kedua kelompok. Secara spesifik, gambaran CD3, CD5, dan CD12 pada wisatawan lebih kuat dibandingkan non-wisatawan. Di sisi lain, citra non-pengunjung dalam bentuk CD2, CD6, CD7, CD8, CD9, dan CD11 lebih kuat dari pada wisatawan. Berdasarkan temuan tersebut, Jepang sebaiknya menyesuaikan strategi promosinya berdasarkan sasarannya, baik wisatawan yang sudah memiliki pengalaman aktual maupun non-wisatawan yang hanya mengandalkan citra sekundernya.
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Ahn, Ji Young, and Bong Seok Choi. "Application of a Cold Dry Air Provocation Test in Pediatric Patients with Asthma." Children 9, no. 6 (June 19, 2022): 920. http://dx.doi.org/10.3390/children9060920.

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Asthma is a chronic inflammatory airway disease characterized by reversible airway obstruction and airway hyperreactivity. We proposed a cold dry air (CDA) provocation test and investigated its application in pediatric patients with asthma. We enrolled 72 children and adolescents older than 5 years who presented to our hospital with chronic cough, shortness of breath, and wheezing. We analyzed the results of allergy, pulmonary function, methacholine provocation, and CDA provocation tests. The FEV1 change 5 min after the provocation was recorded as CDA5 dFEV1; that after 15 min was recorded as CDA15 dFEV1. PT10 was the provocation time causing a 10% decrease in FEV1; a decrease of >10% in dFEV1 was considered a positive CDA test. Among the 72 subjects, 51 were diagnosed with asthma. A positive CDA test in patients with asthma correlated with non-eosinophilic asthma. In patients with asthma, sputum eosinophils and eosinophil cationic protein (ECP) levels of the patients with a positive CDA test were significantly lower than those of patients with a negative test. CDA5 dFEV1 correlated with PC20 and total immunoglobulin E. CDA15 dFEV1 correlated with PC20, sputum eosinophils, and ECP. PT10 became shorter as the peripheral blood eosinophil, FVC, FEV1, FEV1/FVC, and FEF25-75 decreased. The CDA provocation test showed airway hyperreactivity to non-specific stimuli, a high correlation with non-eosinophilic asthma, and the possibility of assessing asthma severity via PT10.
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Barber, Kirk. "CDA 2021 Conference Abstracts." Journal of Cutaneous Medicine and Surgery 25, no. 1_suppl (September 2021): 1S. http://dx.doi.org/10.1177/12034754211037088.

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Dissertations / Theses on the topic "CDA"

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Hayes, Angela Elizabeth. "Production of the calcium-dependent antibiotic (CDA) by Streptromyces coelicolor and Streptomyces lividans : molecular biology of cdaR and other genes from the cda cluster." Thesis, University of Manchester, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506567.

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The calcium-dependent antibiotic (CDA) is a non-ribosomally synthesised lipopeptide produced by Streptomyces coelicolor A3(2). The cda biosynthesis gene cluster occupies approximately 83 kb at the 10 o'clock region of the chromosome. A gene encoding a positive regulator of CDA production, designated cdaR, had been previously identified. Sequence similarly suggests that CdaR is a member of the Streptomyces antibiotic regulatory protein (SARP) family. CdaR is predicted to be 638 amino acid residues in size with a putative ATP/GTP-binding site motif A located in its C-terminal region. Mapping of the transcription start point of cdaR found that it possesses an unusually long untranslated leader sequence of 358 nt. cdaR transcripts were easily detectable at the earliest time point examined (24 h) and decreased over time. A 0.75 kb in-frame deletion in cdaR abolished CDA production. Nuclease protection experiments, using RNA isolated from a S. coelicolor cdaR deletion mutant, indicated that CdaR is required for transcription of some of the genes within the cda cluster, including itself. His6-tagged CdaR was produced in E. coli. Preliminary evidence from mobility shift assays suggested that CdaR binds directly to the 5' end of cdaR and also possibly to the promoter region of cdaPSI (peptide synthetase 1). Unexpectedly, introducing multiple copies of cdaR (approximately 50 copies/chromosome) into S. coelicolor 2377 and MT1110 did not detectably increase CDA production. Correspondingly cdaR transcripts only increased by ~ 30% in S. coelicolor MT1110 containing multiple copies of cdaR; this result suggests that transcription of cdaR is very tightly regulated.
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Kulkarni, Dattatraya H. "CDA, computation decomposition and alignment." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0008/NQ27983.pdf.

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Gaeta, Maria Maddalena. "Il procedimento deliberativo del cda di s.r.l." Thesis, Universita' degli Studi di Catania, 2011. http://hdl.handle.net/10761/339.

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La tesi, intitolata, e' Il procedimento deliberativo del cda di s.r.l. ha ad oggetto la verifica circa la sussistenza della eadem ratio per l'applicazione alla s.r.l. delle norme previste per il consiglio di amministrazione della societa' azionaria. Nel mutato quadro della societa' a responsabilita' limitata, infatti, le regole del procedimento deliberativo del cda, sulle quali il nuovo art. 2475 non interviene espressamente, devono individuarsi e ricostruirsi previa verifica della sussistenza dell'eadem ratio per l'applicazione analogica delle norme che regolano il procedimento deliberativo del consiglio di amministrazione della s.p.a. (artt. 2381-2388) e, dunque, nello specifico, verificando la sussistenza della eadem ratio della collegialita' nell'una e nell'altra societa' anche, ad esempio, rispetto alla logica dei flussi informativi pre-consiliari, necessari nella s.p.a. ma non indispensabili nei modelli convenzionali di s.r.l. piu' aderenti ad una versione, per cosi' dire, personalistica
the thesis, entitled, "The deliberative procedure of the cda of s.r.l." has to object the verification around the subsistence of the eadem ratio for the application to the s.r.l. of the anticipated norms for the board of directors of the stock society. In the changed picture of the responsibility limited society, in fact, the rules of the deliberative procedure of the cda, on which the new art. 2475 don't expressly intervene, you/they must individualize him and to reconstruct him previous verification of the subsistence of the eadem ratio for the analogical application of the norms that you/they regulate the deliberative procedure of the board of directors of the s.p.to. (artt. 2381-2388) and, therefore, in the specific one, also verifying the subsistence of the eadem ratio of the collegiality in the one and in the other society, for instance, in comparison to the logic of the informative flows pre-consiliari, necessary in the s.p.to. but not essential in the conventional models of s.r.l. more adherent to a version, for so to say, personalistica.
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George, Stephen J. "Community of Inquiry Meets Critical Discourse Analysis (CDA): A CDA of Asynchronous Computer-Conference Discourse with Seminary Students in India." Thesis, University of North Texas, 2017. https://digital.library.unt.edu/ark:/67531/metadc1011816/.

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The purpose of this study was to better understand student learning in asynchronous computer-conference discourse (ASD) for non-native speakers of English in India through the Community of Inquiry (COI) framework. The study looked at ASD from an online course taught in the fall of 2015 to 25 students in a seminary in South India. All but one of the students were non-native speakers of English. The class consisted of 22 men and 3 women. Eight students spoke languages from the Dravidian family of languages (Malayalam, Tamil, Telegu and Kannada). Eight students were from the Northeastern states of Manipur, Nagaland and Tripura, where most languages are from the Sino-Tibetan family. Three students were native speakers of Indo-Aryan languages (Odiya and Assamese). Five students were from Myanmar representing several Sino-Tibetan languages. The COI is a framework used to understand learning in ASD, often used in online learning. To study the ASD of this group, critical discourse analysis (CDA) was used with the COI to capture the unique socio-cultural and linguistic conditions of this group. The study revealed that non-native speakers of English often reach the Exploration phase of learning but rarely show evidence of reaching the Resolution phase. This phenomenon was also observed in native English speakers as reported in the literature. Also, the structure of ASD showed that students took an examination approach to discussion shaped in part by their epistemology. This examination approach shaped how knowledge was constructed. CDA also showed that the discourse acquired an instructor-centered structure in which Resolution and Repair were initiated and finalized by the instructor. The study advances the COI framework by undergirding it with a theory of asynchronous discourse using critical discourse analysis and capturing cognitive, social and teaching presence phenomena for non-native speakers that were not observed through the traditional COI framework. These phenomena were driven by cultural, epistemological, and linguistic forces and require a rethinking of the COI for contexts outside of North America. The study also demonstrates that learning for non-native speakers in ASD is challenged by these very same forces. Therefore, design for online learning should account for these phenomena.
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Ellece, Sibonile Edith. "Gendered Marrige Discourses in Botawana : A CDA Approach." Thesis, Lancaster University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.507051.

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FARINA, VINCENZO. "Ruoli ed efficacia del Cda degli intermediari finanziari." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2009. http://hdl.handle.net/2108/1041.

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Un sistema di governance può essere definito come un sistema coerente ed articolato di regole, di strutture e di processi, che assicura la direzione, il controllo e l’accountability delle imprese. Negli ultimi anni il miglioramento dei sistemi di governance è divenuto un obiettivo prioritario nella convinzione che essi possano contribuire ad aumentare la performance aziendale e che l’efficacia della governance dipenda in buona misura dalla qualità della struttura e dei meccanismi decisionali dei Cda. Le impostazioni prevalenti negli studi sui Cda riconoscono la necessità di contemperare le esigenze di composizione e rappresentazione degli interessi dei diversi stakeholder, enfatizzando la possibilità di ridurre i costi di agenzia. Una prospettiva complementare considera l’acquisizione ed il controllo delle risorse critiche strettamente correlati all’attivazione di relazioni con gli attori più influenti del proprio network. All’interno di questa prospettiva si afferma l’elevato potere istituzionale degli intermediari finanziari in virtù del maggiore controllo della risorsa critica rappresentata dal capitale. Il lavoro si pone l’obiettivo di verificare l’ipotesi di una relazione positiva fra potere istituzionale e performance degli intermediari finanziari e si inserisce all’interno dell’ultima prospettiva di ricerca contribuendo al suo arricchimento, sia sul piano dei contenuti sia su quello degli strumenti utilizzabili. Sul piano dei contenuti, sono ancora limitati gli studi che analizzano i legami fra potere istituzionale e performance nella prospettiva delle relazioni (Cotter, Shivdasani, Zenner 1997; Brown, Maloney 1999; Davis, Mizruchi 1999; Miwa, Ramseyer 2000; Ferris, Jagannathan, Pritchard 2003) e solo pochi fra questi prendono in considerazione gli intermediari finanziari. Sul piano degli strumenti, il lavoro si distingue per l’applicazione della social network analysis (Mitchell 1969; Wasserman, Faust 1994) per la misurazione del potere istituzionale degli intermediari finanziari, inteso come la centralità nel network degli interlocking directorates, ossia i legami tra società quando una stessa persona è membro dei rispettivi Consigli di amministrazione. A livello di risultati emergono due evidenze: i) gli intermediari finanziari sono effettivamente gli attori che detengono il maggior potere istituzionale nel network degli interlocking directorates che essi formano con le imprese del campione analizzato e costituito da 255 società quotate su Borsa Italiana Spa nel 2006; ii) il contributo dato dalla qualità delle relazioni (misurata attraverso l’indicatore della betweenness o centralità) alla performance è positivo e significativo.
Corporate governance can be defined as an articulated system of rules, structures and processes aimed to assure the management, the control and the accountability of firms. During the last few years the improvement of governance systems has become a priority objective due to the conviction that these systems can contribute to increase performance which is firstly based on the effective functioning of boards of directors (BoDs). Main studies on the BoDs recognize the necessity to represent the interests of stakeholders, emphasizing the possibility to reduce agency costs. A complementary perspective considers the acquisition and the control of the critical resources closely related to the activation of relations with the more influential actors of the network. In this view, financial intermediaries have the greater institutional power due to their larger control of capital flows. This work’s purpose is to verify the hypothesis of a positive relationship between institutional power and performance of financial intermediaries, taking into consideration the last perspective, contributing to its enrichment, both on contents and tools of analysis levels. Regarding the contents, studies that analyze the relationships between institutional power and performance in the perspective of governance relations are still limited (Cotter, Shivdasani, Zenner 1997; Brown, Maloney 1999; Davis, Mizruchi 1999; Miwa, Ramseyer 2000; Ferris, Jagannathan, Pritchard 2003) and only few of these take into consideration the financial intermediaries. Regarding the tools of analysis, this work is distinguished for the application of social network analysis (Mitchell 1969; Wasserman, Faust 1994) for the measurement of the institutional power of the financial intermediaries (i.e. the centrality in the network of the interlocking directorates). From results emerge two evidences: i) financial intermediaries are effectively the actors with the greater institutional power in the network of the interlocking directorates referred to a sample of 255 firms listed on Borsa Italiana Spa in 2006; ii) the contribution given from the quality of the relationships to the performance is positive and significant.
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Aldadah, Yasmin. "CDA analysis of Jerusalem Conflict in BBC and AJE." Thesis, Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-67498.

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This research aims at finding how BBC and AJE media represented the Israeli-Palestinian conflict. The study examines the news website, which reported the recent escalation of Jerusalem conflict in December 2017, where US President Trump have recognized Jerusalem as Israeli capital, and declared to move the US embassy from Tel-Aviv to Jerusalem. The study uses qualitative research, where it investigated the impact of ideology on media discourse by means of critical discourse analysis (DHA, Topoi, and Social actor’s representation). CDA was carried out for a sample of 8 news articles published on the websites of two networks: the British Broadcasting Corporation World news "BBCWN" and the Middle Eastern Qatari owned "Al Jazeera English". The articles were chosen within the month of December 2017. Articles were analyzed by means of the two-level analysis method, including the thematic and in-depth analysis. On the first, entry-level analysis, I focus on contents of texts and outline the discourse topics. While in the second phase I analyze the means of discursive strategies and the representation of social actors utilized throughout the text. The thematic analysis revealed that, both BBC and AJE have covered the incident similarly in general look. However, in-depth analysis showed that each network had portrayed the images of Israelis and Palestinians differently. On contrast of AJE, BBC tends to perceive Palestinians as a threat and the Israeli one as victims of the Palestinian violation. Moreover, the analysis revealed that each network had different ideologies and aims. The study concludes that AJE articles was biased pro-Palestinians, while BBC articles was biased pro-Israelis.
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Matuschek, Andreas [Verfasser]. "Epidemiologie der Kongenitalen Dyserythropoietischen Anämie (CDA) in Europa / Andreas Matuschek." Ulm : Universität Ulm. Medizinische Fakultät, 2013. http://d-nb.info/1032243716/34.

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Napel, Hans-Martien Thijs Dominique ten. "Een eigen weg : de totstandkoming van het CDA (1952-1980) /." [S.l. : s.n], 1992. http://catalogue.bnf.fr/ark:/12148/cb37147399r.

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Liljeholm, Maria. "Congenital Dyserythropoietic Anemia type III (CDA III) : diagnostics, genetics and morbidity." Doctoral thesis, Umeå universitet, Institutionen för strålningsvetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-117454.

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The Congenital Dyserythropoietic Anemias (CDA) are rare hereditary hemolytic disorders with large bi- to multi-nucleated erythroblasts in the bone marrow. Hemolysis is negative in a direct antiglobulin test (DAT). Based on morphology and clinical picture, three major forms of CDAs, type I, II, and III have been defined. CDA III, dominantly inherited, constitutes the rarest type with a majority of cases belonging to a family in Västerbotten, Sweden. The genetic background of CDA I and CDA II has been linked to mutations in CDAN1 and SEC23B respectively. The mutation of CDA III has been linked to 15q22 in earlier studies. In this project we have defined the causative genetic lesion in two families with CDA III. The novel mutation KIF23 c.2747C>G (p.P916R) was shown to segregate with CDA III in the Swedish and American CDA III families and was absent in 356 healthy controls. KIF23 encodes mitotic kinesin-like protein 1 (MKLP1), which plays a central role in the last step of cytokinesis. RNAi-based knock-down and rescue experiments demonstrated that the p.P916R mutation causes cytokinesis failure in HeLa cells, resulting in increasing number of bi-nuclear cells, consistent with appearance of large multinucleated erythroblasts in CDA III patients. We conclude that CDA III is caused by a mutation in KIF23, encoding MKLP1, a conserved mitotic kinesin crucial for cytokinesis. Flow cytometry with eosin-5´-maleimide (EMA), anti-CD55 and anti-CD59 is commonly used when investigating non-autoimmune hemolytic anemias. Reduced fluorescence of EMA, typically detected in hereditary spherocytosis, is also seen in CDA II, while reduction of CD55 and CD59 characterizes paroxysmal nocturnal hemoglobinuria (PNH). We studied the flow cytometric profile of EMA, CD55, and CD59 on erythrocytes in CDA III. We found no abnormality of the erythrocyte membrane in CDA III and concluded that standard flow cytometry cannot be used to discriminate between CDA III and normal controls. In CDA I and CDA II a majority of patients, including those who are not transfusion dependent, suffer from iron overload, which, according to earlier studies, is not the case in CDA III. We found that individuals of the Västerbotten CDA III family carry mutations in the hemochromatosis (HFE) gene. Three CDA III patients with heterozygous or compound HFE mutations need treatment with phlebotomy due to iron overload. One of them carries heterozygous H63D mutation, which is not reported to lead to iron overload by itself in otherwise healthy individuals. We propose that molecular genetic testing of the HFE gene is indicated in all patients with CDA, including CDA III.
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Books on the topic "CDA"

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Association, Colour Dimensions. CDA directory. London (44 Rockley Rd, London, W14 0BT): Colour Dimensions Association, 1995.

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Boone, Keith W. The CDA TM book. London: Springer London, 2011. http://dx.doi.org/10.1007/978-0-85729-336-7.

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1957-, Schummer Uwe, ed. CDA, 1945 bis 1995. Königswinter: CDA-Verlagsgesellschaft, 1995.

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Kulkarni, Dattatraya H. CDA: Computation decomposition and alignment. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1997.

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United States. National Aeronautics and Space Administration., ed. System critical design audit (CDA). [Cleveland, Ohio]: TRW, 1995.

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Stewart, Brenda. Victorian decorative painting with Brenda Stewart, CDA. Cincinnati, Ohio: North Light Books, 1999.

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van, Ark Rijk, ed. 25 jaar CDA: Tussen macht en inhoud. Baarn: Tirion, 2005.

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Metze, Marcel. De stranding: Het CDA van hoogtepunt naar catastrofe. Nijmegen: SUN, 1995.

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Committee, Canadian Dental Association Third Party Dental Plans. CDA uniform system of coding & list of services. Ottawa: Canadian Dental Association, 1992.

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CDA: Il mito della commedia dell'arte nell'Ottocento francese. Roma: Bulzoni, 1999.

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Book chapters on the topic "CDA"

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Chavez, Edgar, Ubaldo Ruiz, and Eric Tellez. "CDA: Succinct Spaghetti." In Similarity Search and Applications, 54–64. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-25087-8_5.

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Kulkarni, Dattatraya, and Michael Stumm. "CDA Loop Transformations." In Languages, Compilers and Run-Time Systems for Scalable Computers, 29–42. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4615-2315-4_3.

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Schenkel-Brunner, Helmut. "HEMPAS (CDA-II)." In Human Blood Groups, 606–14. Vienna: Springer Vienna, 2000. http://dx.doi.org/10.1007/978-3-7091-6294-1_32.

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Reisigl, Martin, and Friedemann Vogel. "Kritische Diskursanalyse/CDA." In Handbuch Sprachkritik, 189–95. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-04852-3_24.

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Benson, Tim, and Grahame Grieve. "CDA – Clinical Document Architecture." In Principles of Health Interoperability, 283–301. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-30370-3_15.

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Nahler, Gerhard. "confidential disclosure agreement (CDA)." In Dictionary of Pharmaceutical Medicine, 37. Vienna: Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_271.

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Benson, Tim, and Grahame Grieve. "CDA—Clinical Document Architecture." In Principles of Health Interoperability, 233–54. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-56883-2_13.

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Boone, Keith W. "The CDA™ Header." In The CDA TM book, 133–69. London: Springer London, 2011. http://dx.doi.org/10.1007/978-0-85729-336-7_14.

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Boone, Keith W. "The CDA™ Body." In The CDA TM book, 171–87. London: Springer London, 2011. http://dx.doi.org/10.1007/978-0-85729-336-7_15.

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Boone, Keith W. "Organization of This Book." In The CDA TM book, 1–7. London: Springer London, 2011. http://dx.doi.org/10.1007/978-0-85729-336-7_1.

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Conference papers on the topic "CDA"

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Jung, Sungwon, and Jinwook Choi. "Generation of Level 3 CDA Document Using CDA Studio." In 2007 International Conference on Convergence Information Technology (ICCIT 2007). IEEE, 2007. http://dx.doi.org/10.1109/iccit.2007.248.

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Jung, Sungwon, and Jinwook Choi. "Generation of Level 3 CDA Document Using CDA Studio." In 2007 International Conference on Convergence Information Technology (ICCIT 2007). IEEE, 2007. http://dx.doi.org/10.1109/iccit.2007.4420445.

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Zheng Liang, P. Bodorik, and M. Shepherd. "Storage model for CDA documents." In 36th Annual Hawaii International Conference on System Sciences, 2003. Proceedings of the. IEEE, 2003. http://dx.doi.org/10.1109/hicss.2003.1174352.

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Yuwen, Shuli, and Xiaoping Yang. "Conversion between SNOMED and CDA." In 2010 International Conference on Biomedical Engineering and Computer Science (ICBECS). IEEE, 2010. http://dx.doi.org/10.1109/icbecs.2010.5462502.

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Huang, Zhengxing, Xudong Lu, Huilong Duan, and Haomin Li. "Enhanced CDA with Electronic Signature." In 2007 1st International Conference on Bioinformatics and Biomedical Engineering. IEEE, 2007. http://dx.doi.org/10.1109/icbbe.2007.300.

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Purushothaman, Yuvaraj, Hoon Choi, Narayan Yoganandan, Jamie Baisden, Deepak Rajasekaran, and Davidson Jebaseelan. "Biomechanical Study of Cervical Disc Arthroplasty Devices Using Finite Element Models." In ASME 2020 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/imece2020-24123.

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Abstract Various types and designs of artificial discs for cervical disc arthroplasty (CDA) have been introduced to overcome the disadvantages of the conventional anterior cervical discectomy and fusion (ACDF). The purpose of this study was to evaluate the effects of different CDA designs on the range of motion (ROM), intradiscal pressure (IDP), and facet force variables with different types of FDA-approved CDA devices under normal physiological loading conditions. A validated three-dimensional finite element model (FEM) of the intact cervical spinal column (C2-T1) was used in the present study. The intact spine model was modified and used for postoperative FE models simulating CDAs implanted at the C5-C6 intervertebral disc space. The normal surgical procedures were used in the simulations. The hybrid loading protocol (intact spine loading: 2 Nm) with a compressive follower force of 75 N was applied at the superior end of the spine. The inferior endplate of C7 vertebra was constrained in all directions. Flexion, extension, and lateral bending loading conditions were simulated in all models: intact spine and models with different CDA devices. At the index level, all CDAs except the Bryan disc showed an increase in motion, and the range of motions at the adjacent levels decreased in flexion, extension, and lateral bending modes. The largest increase in motion occurred during lateral bending. The Bryan disc reduced the segmental motion at the index level under flexion, extension, and lateral bending, and had compensatory increases in motion at the adjacent levels. The intradiscal pressure reduced at the adjacent levels with Mobi-C and Secure-C devices. The Bryan and Prestige LP devices showed increases in the intradiscal pressure at the adjacent levels due to the reduced index level motion (Bryan disc) and the metal-on-metal design (Prestige LP). The facet force increased at the index level in all CDAs, with the highest force with Mobi-C, and this was attributed to its unrestrained design. The facet force generally decreased at the adjacent levels with CDAs, except for the Bryan disc, due to reduced index level motion, and the Prestige LP in lateral bending, likely due to its metal-on-metal design. The present study demonstrates the influence of different CDA designs on the anterior and posterior loading patterns at the index and adjacent levels. In addition, the study validates key clinical observations: CDA procedure is contraindicated in cases of facet arthropathy; and CDA may be protective against adjacent segment degeneration.
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Jackson, Michael R. C. "CDA with RTA in a mixed environment." In 2009 IEEE/AIAA 28th Digital Avionics Systems Conference (DASC). IEEE, 2009. http://dx.doi.org/10.1109/dasc.2009.5347545.

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Li, Haomin, Huilong Duan, Xudong Lu, and Zhengxing Huang. "A Clinical Document Repository for CDA Documents." In 2007 1st International Conference on Bioinformatics and Biomedical Engineering. IEEE, 2007. http://dx.doi.org/10.1109/icbbe.2007.280.

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Yun, Ji Hyun, and Il Kon Kim. "Processing HL7-CDA Entry for Semantic Interoperability." In 2007 International Conference on Convergence Information Technology (ICCIT 2007). IEEE, 2007. http://dx.doi.org/10.1109/iccit.2007.102.

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Yun, Ji Hyun, and Il Kon Kim. "Processing HL7-CDA Entry for Semantic Interoperability." In 2007 International Conference on Convergence Information Technology (ICCIT 2007). IEEE, 2007. http://dx.doi.org/10.1109/iccit.2007.4420535.

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Reports on the topic "CDA"

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Trujillo, Gabrielle. FY20Q3 CDA. Office of Scientific and Technical Information (OSTI), June 2020. http://dx.doi.org/10.2172/1763582.

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Wheelock, Margaret. Expression of Inappropriate Cadherins in Human Breast Carcinomas-CDA. Fort Belvoir, VA: Defense Technical Information Center, October 1999. http://dx.doi.org/10.21236/ada382945.

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Gómez Ortega, Luis Fernando, Leonardo Yunda Perlaza, and Myriam Leonor Torres Pérez. Selección de documento para mapeo a formato HL7 -CDA. Universidad Nacional Abierta y a Distancia - UNAD, 2020. http://dx.doi.org/10.22490/ecisa.4764.

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El presente documento de trabajo se centra en el proceso de selección de un documento clínico para hacer el mapeo a HL7 CDA en el marco del proyecto denominado “Diseño y construcción de un documento HL7 CDA para historia clínica colombiana”. En Colombia existe diversidad de documentos clínicos susceptibles mapear a documento CDA, sin embargo, para el proyecto se seleccionó un documento que permite integrar la mayor cantidad de orígenes de datos, para que los estudiantes de los cursos Sistemas de información y calidad en salud, interoperabilidad de los sistemas de información en salud y Telesalud, puedan utilizarlos y reconocer la relación entre los diferentes sistemas de gestión. En adelante se procede a explicar el proceso de selección del documento clínico y su respectiva justificación de acuerdo con las necesidades del proyecto.
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Gómez Ortega, Luis Fernando, Leonardo Yunda Perlaza, Myriam Leonor Torres Pérez, and Claudio Camilo González Clavijo. Diseño de software de simulación para generar un documento clínico XML - CDA. Universidad Nacional Abierta y a Distancia - UNAD, 2020. http://dx.doi.org/10.22490/ecisa.4754.

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El presente documento de trabajo se centra en el proceso de diseño de un simulador que permita llenar un documento denominado epicrisis y generar un documento XML-CDA y PDF, en el marco del proyecto denominado “Diseño y construcción de un documento HL7 CDA para historia clínica colombiana”. En el proyecto “Diseño y construcción de un documento HL7 CDA para historia clínica colombiana”, se plantea el mapeo de un documento clínico al estándar HL7 CDA, sin embargo, el equipo de investigadores decidió llevar el proyecto mas allá de lo esperado y para la generación del CDA se propuso la creación de un simulador software, para que los estudiantes puedan interactuar con el y tener una experiencia mucho más completa que solo recibir la explicación del mapeo. En el diseño del software se tuvieron en cuenta los requerimientos encontrados haciendo el cruce de las temáticas abordadas por cursos académicos afines y las áreas de cobertura del simulador. Para realizar el diseño se utilizaron diagramas del lenguaje de modelado unificado UML además del modelo relacional de bases de datos. En adelante se procede a explicar el proceso de diseño del simulador y su respectiva justificación de acuerdo con las necesidades del proyecto.
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Gómez Ortega, Luis Fernando, Leonardo Yunda Perlaza, Myriam Leonor Torres Pérez, and Claudio Camilo González Clavijo. Desarrollo de software de simulación para generar un documento clínico XML - CDA. Universidad Nacional Abierta y a Distancia - UNAD, 2021. http://dx.doi.org/10.22490/ecisa.4753.

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El presente documento de trabajo se centra en el proceso de desarrollo de un simulador que permita llenar los campos de un documento denominado epicrisis y generar un documento XML-CDA y PDF, en el marco del proyecto denominado “Diseño y construcción de un documento HL7 CDA para historia clínica colombiana”. En el proyecto “Diseño y construcción de un documento HL7 CDA para historia clínica colombiana”, se plantea el desarrollo de un simulador basado en software para ser usado en la formación de estudiantes de la escuela de ciencias de la salud de la Universidad Nacional Abierta y a Distancia. El propósito del software es poder brindar a los estudiantes una experiencia mucho más completa que la actual, a través del diligenciamiento del documento epicrisis que incluye aspectos legislativos, conjuntos estandarizados de datos y el uso de estándares como Loinc y HL7. En adelante se procede a explicar el proceso de desarrollo del simulador y su respectiva justificación de acuerdo con las necesidades del proyecto.
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Mekova, Ralitsa V., Spaska S. Lesichkova, Adelina D. Tsakova, Julieta Z. Bakalova, Deniz Bakalov, and Mihail Boyanov. Circulating CD3(+)CD4(+)CD28(‒) T Lymphocytes in Patients with Autoimmune Thyroiditis. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, May 2020. http://dx.doi.org/10.7546/crabs.2020.05.14.

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Medof, M. E. Augmentation of Antitumor T-Cell Responses by Increasing APC T-Cell C5a/C3a-C5aR/C3aR Interactions. Fort Belvoir, VA: Defense Technical Information Center, March 2013. http://dx.doi.org/10.21236/ada585489.

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Ames, A. L. Immersive CAD. Office of Scientific and Technical Information (OSTI), February 1999. http://dx.doi.org/10.2172/3674.

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Langeveld, Willy G. J. The CAD-EGS Project: Using CAD Geometrics in EGS4. Office of Scientific and Technical Information (OSTI), March 2002. http://dx.doi.org/10.2172/799112.

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AMES, ARLO L. Cloud to CAD. Office of Scientific and Technical Information (OSTI), May 2001. http://dx.doi.org/10.2172/782599.

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