Log in

Relevant bibliographies by topics / CDC / Journal articles

To see the other types of publications on this topic, follow the link: CDC.

Journal articles on the topic 'CDC'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'CDC.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Idigbe, Emmanuel Oni, Rosemary A. Audu, Edna O. Iroha, et al. "T-Lymphocyte Subsets in Apparently Healthy Nigerian Children." International Journal of Pediatrics 2010 (2010): 1–7. http://dx.doi.org/10.1155/2010/474380.

Full text

Abstract:

Population studies showed that there are differences in T-lymphocytes subpopulation of normal children in different regions, and reference values in an area might be different from another. This study compared the values in our population with CDC and WHO reference values. Blood samples from 279 healthy, HIV-negative children<12 years of age were analysed for complete blood count, CD3+, CD4+, CD8+ counts and percentages. Except for CD8%, mean values for all parameters measured significantly decreased with age. CD4+ counts were higher in females than males,P<.05. Using the WHO criteria, 1

APA, Harvard, Vancouver, ISO, and other styles

2

Chatila, T. A., and R. S. Geha. "Phosphorylation of T cell membrane proteins by activators of protein kinase C." Journal of Immunology 140, no. 12 (1988): 4308–14. http://dx.doi.org/10.4049/jimmunol.140.12.4308.

Full text

Abstract:

Abstract Activation of the enzyme protein kinase C (PKC) plays an important role in T cell activation. We investigated the phosphorylation of CD2, CD3, CD4, CD5, CD7, CD8, CD28 (Tp44), CD43 (sialophorin, gp115), and LFA-1 after incubation of human PBMC with the (PKC) activator PMA. These proteins were chosen for their role in transmembrane signal transduction (CD2, CD3, CD5, CD28, CD43), cell-cell interaction and adhesion (CD2, CD4, CD8, and LFA-1), or involvement in immunodeficiency states (CD43, CD7). CD5, CD7, CD43, and the alpha-chain of LFA-1 were found to be constitutively phosphorylated

APA, Harvard, Vancouver, ISO, and other styles

3

Raimondi, SC, FG Behm, PK Roberson, et al. "Cytogenetics of childhood T-cell leukemia." Blood 72, no. 5 (1988): 1560–66. http://dx.doi.org/10.1182/blood.v72.5.1560.1560.

Full text

Abstract:

Abstract The karyotypes of 57 cases of childhood T-cell acute lymphoblastic leukemia (ALL) were analyzed to establish the cytogenetic profile in this disease. Three questions were of particular interest. Do the chromosomal changes in T-cell ALL preferentially affect bands where genes encoding the T-cell receptor for antigen (TCR) have been mapped? Do alterations involving the TCR gene regions appear with any notable frequency in B-progenitor ALL? Do chromosomal abnormalities in this disease relate to stage of T-cell ontogeny? A relatively high proportion of cases (65%) had a pseudodiploid kary

APA, Harvard, Vancouver, ISO, and other styles

4

Raimondi, SC, FG Behm, PK Roberson, et al. "Cytogenetics of childhood T-cell leukemia." Blood 72, no. 5 (1988): 1560–66. http://dx.doi.org/10.1182/blood.v72.5.1560.bloodjournal7251560.

Full text

Abstract:

The karyotypes of 57 cases of childhood T-cell acute lymphoblastic leukemia (ALL) were analyzed to establish the cytogenetic profile in this disease. Three questions were of particular interest. Do the chromosomal changes in T-cell ALL preferentially affect bands where genes encoding the T-cell receptor for antigen (TCR) have been mapped? Do alterations involving the TCR gene regions appear with any notable frequency in B-progenitor ALL? Do chromosomal abnormalities in this disease relate to stage of T-cell ontogeny? A relatively high proportion of cases (65%) had a pseudodiploid karyotype at

APA, Harvard, Vancouver, ISO, and other styles

5

Semchenkova, Alexandra, Ekaterina Mikhailova, Irina Demina, et al. "Analysis of Antigen Expression in T-Cell Acute Lymphoblastic Leukemia by Multicolor Flow Cytometry: Implications for the Detection of Measurable Residual Disease." International Journal of Molecular Sciences 26, no. 5 (2025): 2002. https://doi.org/10.3390/ijms26052002.

Full text

Abstract:

Multicolor flow cytometry (MFC) is a key method for assessing measurable residual disease (MRD) in acute lymphoblastic leukemia (ALL). However, very few approaches were developed for MRD in T-cell ALL (T-ALL). To identify MRD markers suitable for T-ALL, we analyzed the expression of CD2, CD3, CD4, CD5, CD7, CD8, CD10, CD34, CD45, CD48, CD56, CD99, and HLA-DR in T-ALL patients at diagnosis. The median fluorescence intensities (MFIs) of surface CD3, CD4, CD5, CD7, CD8, CD45, CD48, CD99, and CD16+CD56 were also evaluated at Day 15 and the end-of-induction (EOI). The MFC data from 198 pediatric T-

APA, Harvard, Vancouver, ISO, and other styles

6

Amalia, Fatya Alty, Arie Indra Gunawan, and Nono Wibisono. "Citra Destinasi Wisata Halal di Jepang: Wisatawan Dan Non-Wisatawan Muslim Dari Indonesia." Jurnal Bisnis dan Kewirausahaan 17, no. 1 (2021): 1–10. http://dx.doi.org/10.31940/jbk.v17i1.2473.

Full text

Abstract:

Wisata halal merupakan salah satu sektor bisnis halal yang masih berkembang karena banyaknya potensi wisatawan yang masih dapat dimanfaatkan lebih lanjut. Sebagai seorang wisatawan yang memiliki beberapa pilihan destinasi wisata halal, proses pengambilan keputusannya mengenai destinasi yang dipilih dapat sangat dipengaruhi oleh citra destinasi pada atribut wisata halal di destinasi tersebut. Penelitian ini bertujuan untuk mengkaji citra destinasi wisata halal di Jepang dari wisatawan dan non-wisatawan muslim Indonesia. Untuk pendataan dilakukan survey online (Mei-Juni 2020) terhadap umat Islam

APA, Harvard, Vancouver, ISO, and other styles

7

Takamatsu, Hiroyuki, Yoshihiro Yakushijin, Koji Miyazaki, et al. "C-Terminal Defect of CD20 on T-Cell Leukemia/Lymphoma Cells: Implications for Resistance to Rituximab." Blood 112, no. 11 (2008): 5267. http://dx.doi.org/10.1182/blood.v112.11.5267.5267.

Full text

Abstract:

Abstract Rituximab is commonly used for treatment of B-cell leukemia/lymphoma and its efficiency on CD20+ B-cell malignancies has been established. On the other hand, the effect of rituximab on CD20+ T cell leukemia/lymphoma is unclear. Two patients CD20+ T-cell malignancy (1 with T-cell prolymphocytic leukemia (T-PLL) and 1 with peripheral T-cell lymphoma, unspecified (PTCL-u)) were recently treated with rituximab without appreciable effects. The treatment failure prompted a study of the mechanisms underlying the resistance to rituximab therapy using leukemia/lymphoma cells of these patients

APA, Harvard, Vancouver, ISO, and other styles

8

Abbott, Daniel, Steven Kroft, Maria Hintzke, et al. "Immunophenotypic Analysis of Peripheral T-Cell Lymphomas: A Single-Center Retrospective Review of Flow Cytometric Analysis." American Journal of Clinical Pathology 152, Supplement_1 (2019): S109. http://dx.doi.org/10.1093/ajcp/aqz121.012.

Full text

Abstract:

Abstract Background Peripheral T-cell lymphomas (PTCLs) are heterogenous, mature T-cell neoplasms that are a diagnostic challenge, requiring a combination of morphologic assessment and ancillary studies. Flow cytometry (FC) is a tool used routinely in lymphoma diagnosis; however, most analyses are limited to B-cell evaluation and pathologists generally lack experience evaluating for PTCL. We aimed to describe the immunophenotypic aberrancies observed by FC in PTCL. Design PTCLs with FC were collected, excluding primary leukemic processes. Four- and eight-color FC data were reanalyzed with the

APA, Harvard, Vancouver, ISO, and other styles

9

Tjønnfjord, G. E., O. P. Veiby, R. Steen, and T. Egeland. "T lymphocyte differentiation in vitro from adult human prethymic CD34+ bone marrow cells." Journal of Experimental Medicine 177, no. 6 (1993): 1531–39. http://dx.doi.org/10.1084/jem.177.6.1531.

Full text

Abstract:

Pluripotent lymphohematopoietic stem cells are probably confined to bone marrow cells expressing CD34 surface molecules. To investigate the capacity of adult human CD34+ bone marrow cells to differentiate along the T lymphoid lineage, we plated purified CD34+ cells from healthy adults in liquid culture on adherent thymic stromal cells prepared from HLA- or blood group-mismatched postnatal thymic tissue. We show that purified CD34+CD3-CD4-CD8- bone marrow cells contained progenitors with the ability to differentiate into CD4+ and CD8+ T lymphocytes expressing surface (s)CD3 and T cell receptor

APA, Harvard, Vancouver, ISO, and other styles

10

Lukens, Michaël V., Debby Kruijsen, Frank E. J. Coenjaerts, Jan L. L. Kimpen, and Grada M. van Bleek. "Respiratory Syncytial Virus-Induced Activation and Migration of Respiratory Dendritic Cells and Subsequent Antigen Presentation in the Lung-Draining Lymph Node." Journal of Virology 83, no. 14 (2009): 7235–43. http://dx.doi.org/10.1128/jvi.00452-09.

Full text

Abstract:

ABSTRACT In the respiratory tract, different dendritic cell (DC) populations guard a tight balance between tolerance and immunity to infectious or harmless materials to which the airways are continuously exposed. For infectious and noninfectious antigens administered via different routes, different subsets of DC might contribute during the induction of T-cell tolerance and immunity. We studied the impact of primary respiratory syncytial virus (RSV) infection on respiratory DC composition in C57BL/6 mice. We also tracked the migration of respiratory DC to the lymph nodes and studied antigen pre

APA, Harvard, Vancouver, ISO, and other styles

11

Teoh, Jeffrey, Michael Stadnisky, Timothy Bullock, and Michael Brown. "Licensed NK-mediated response to murine cytomegalovirus specifically upregulates dendritic cell co-stimulatory ligands required in T cell priming (VIR1P.963)." Journal of Immunology 192, no. 1_Supplement (2014): 74.5. http://dx.doi.org/10.4049/jimmunol.192.supp.74.5.

Full text

Abstract:

Abstract Ly49G2+ (G2+) NK cells mediate murine (M)CMV resistance in mice with the self-MHC Dk ligand expressed. A prior study showed that G2+ NK-mediated MCMV resistance resulted in increased numbers of conventional dendritic cells (cDC) and virus-specific CD8 T cells after infection, independent of CD4 T cells. However, the molecular basis underlying licensed NK-mediated enhancement of T-cell immunity is unknown. Here we examined the role of co-stimulatory ligands expressed in splenic cDC after MCMV infection. An increase in the intracellular expression of both CD86 and CD70 was observed by 7

APA, Harvard, Vancouver, ISO, and other styles

12

Barcena, A., MO Muench, AH Galy, et al. "Phenotypic and functional analysis of T-cell precursors in the human fetal liver and thymus: CD7 expression in the early stages of T- and myeloid-cell development." Blood 82, no. 11 (1993): 3401–14. http://dx.doi.org/10.1182/blood.v82.11.3401.3401.

Full text

Abstract:

Abstract It has been proposed that the CD7 molecule is the first antigen expressed on the membrane of cells committed to the T-cell lineage during human fetal T-cell ontogeny. To further identify the pre-T cell subpopulation that migrates to the thymus early in ontogeny, we analyzed the phenotypic and functional characteristics of the fetal liver populations separated on the basis of CD7 expression. Three populations expressing different levels of CD7 were observed: CD7bright, CD7dull, and CD7-. A CD7bright population depleted of mature T, B, and myeloid cells (lineage negative, lin-) and most

APA, Harvard, Vancouver, ISO, and other styles

13

Barcena, A., MO Muench, AH Galy, et al. "Phenotypic and functional analysis of T-cell precursors in the human fetal liver and thymus: CD7 expression in the early stages of T- and myeloid-cell development." Blood 82, no. 11 (1993): 3401–14. http://dx.doi.org/10.1182/blood.v82.11.3401.bloodjournal82113401.

Full text

Abstract:

It has been proposed that the CD7 molecule is the first antigen expressed on the membrane of cells committed to the T-cell lineage during human fetal T-cell ontogeny. To further identify the pre-T cell subpopulation that migrates to the thymus early in ontogeny, we analyzed the phenotypic and functional characteristics of the fetal liver populations separated on the basis of CD7 expression. Three populations expressing different levels of CD7 were observed: CD7bright, CD7dull, and CD7-. A CD7bright population depleted of mature T, B, and myeloid cells (lineage negative, lin-) and mostly compos

APA, Harvard, Vancouver, ISO, and other styles

14

Delgado-Arévalo, C., M. Calvet-Mirabent, A. Triguero-Martinez та ін. "POS0367 NLRC4 AND FC-γ-R CROSSTALK ON CD1C+ DENDRITIC CELLS DIFFERENTIALLY CONTRIBUTES TO RHEUMATOID ARTHRITIS IMMUNOPATHOLOGY". Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 413.2–413. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3192.

Full text

Abstract:

Background:Rheumatoid arthritis (RA) is an autoimmune disorder in which Th17 cells, B cells and inflammatory cytokines (1-3) contribute to joint tissue damage, however the role of specific myeloid populations to immunopathogenesis of RA remains unclear.Objectives:To address this question, we studied transcriptional, phenotypical and functional characteristics of monocytes (Mo), CD1c+ and CD141+ conventional dendritic cells (cDC) from RA patients.Methods:Frequencies and maturation patterns of Lin-CD14-HLADR+ plasmacytoid (CD11c-), CD1c+ and CD141+ cDC (CD11c+) subsets and CD14+ Mo from n=25 RA

APA, Harvard, Vancouver, ISO, and other styles

15

Weimer, R., V. Daniel, R. Zimmermann, K. Schimpf, and G. Opelz. "Autoantibodies against CD4 cells are associated with CD4 helper defects in human immunodeficiency virus-infected patients." Blood 77, no. 1 (1991): 133–40. http://dx.doi.org/10.1182/blood.v77.1.133.133.

Full text

Abstract:

Abstract To investigate whether autoantibodies against CD4-positive lymphocytes might induce helper dysfunction, autoantibody formation and T-cell function was examined simultaneously in 61 hemophilia patients. Twenty patients were human immunodeficiency virus (HIV)-negative, 26 HIV- positive stage CDC II or III, and 15 were HIV-positive stage CDC IV. T lymphocytes, CD4-positive, or CD8-positive T subsets were cocultured with B lymphocytes and pokeweed mitogen (PWM) for 6 days and Ig- secreting cells were assessed in a reverse hemolytic plaque assay. The presence of IgM, IgG, C3d, or gp120 on

APA, Harvard, Vancouver, ISO, and other styles

16

Weimer, R., V. Daniel, R. Zimmermann, K. Schimpf, and G. Opelz. "Autoantibodies against CD4 cells are associated with CD4 helper defects in human immunodeficiency virus-infected patients." Blood 77, no. 1 (1991): 133–40. http://dx.doi.org/10.1182/blood.v77.1.133.bloodjournal771133.

Full text

Abstract:

To investigate whether autoantibodies against CD4-positive lymphocytes might induce helper dysfunction, autoantibody formation and T-cell function was examined simultaneously in 61 hemophilia patients. Twenty patients were human immunodeficiency virus (HIV)-negative, 26 HIV- positive stage CDC II or III, and 15 were HIV-positive stage CDC IV. T lymphocytes, CD4-positive, or CD8-positive T subsets were cocultured with B lymphocytes and pokeweed mitogen (PWM) for 6 days and Ig- secreting cells were assessed in a reverse hemolytic plaque assay. The presence of IgM, IgG, C3d, or gp120 on the surfa

APA, Harvard, Vancouver, ISO, and other styles

17

Oshi, Masanori, Stephanie Newman, Yoshihisa Tokumaru, et al. "Plasmacytoid Dendritic Cell (pDC) Infiltration Correlate with Tumor Infiltrating Lymphocytes, Cancer Immunity, and Better Survival in Triple Negative Breast Cancer (TNBC) More Strongly than Conventional Dendritic Cell (cDC)." Cancers 12, no. 11 (2020): 3342. http://dx.doi.org/10.3390/cancers12113342.

Full text

Abstract:

Dendritic cells (DC) represent a major antigen-presenting cell type in the tumor immune microenvironment (TIME) and play an essential role in cancer immunity. Conventional DC (cDC) and plasmacytoid DC (pDC) were defined by the xCell algorithm and a total of 2968 breast cancer patients (TCGA and METABRIC) were analyzed. We found that triple-negative breast cancer (TNBC) had a high fraction of cDC and pDC compared to the other subtypes. In contrast to cDC, high pDC in TNBC was significantly associated with better disease-specific and disease-free survival consistently in both cohorts. High cDC T

APA, Harvard, Vancouver, ISO, and other styles

18

Greenberg, JM, and JH Kersey. "Terminal deoxynucleotidyl transferase expression can precede T cell receptor beta chain and gamma chain rearrangement in T cell acute lymphoblastic leukemia." Blood 69, no. 1 (1987): 356–60. http://dx.doi.org/10.1182/blood.v69.1.356.356.

Full text

Abstract:

Abstract The nuclear enzyme terminal deoxynucleotidyl transferase (TdT) is thought to contribute to the diversity of certain immunoglobulin and T cell receptor gene rearrangements through the addition of random nucleotides at their variable (V)-joining (J) region junctions. An acute lymphoblastic leukemia (ALL) with an immature T cell phenotype (CD7+, CD5+, CD1+/-, CD2+/-, CD3-, CD4-, CD8-) was found to be TdT+ with germline immunoglobulin heavy chain, T cell receptor beta chain, and T cell gamma chain genes. The data indicate that TdT expression can precede T gamma and T beta rearrangement du

APA, Harvard, Vancouver, ISO, and other styles

19

Greenberg, JM, and JH Kersey. "Terminal deoxynucleotidyl transferase expression can precede T cell receptor beta chain and gamma chain rearrangement in T cell acute lymphoblastic leukemia." Blood 69, no. 1 (1987): 356–60. http://dx.doi.org/10.1182/blood.v69.1.356.bloodjournal691356.

Full text

Abstract:

The nuclear enzyme terminal deoxynucleotidyl transferase (TdT) is thought to contribute to the diversity of certain immunoglobulin and T cell receptor gene rearrangements through the addition of random nucleotides at their variable (V)-joining (J) region junctions. An acute lymphoblastic leukemia (ALL) with an immature T cell phenotype (CD7+, CD5+, CD1+/-, CD2+/-, CD3-, CD4-, CD8-) was found to be TdT+ with germline immunoglobulin heavy chain, T cell receptor beta chain, and T cell gamma chain genes. The data indicate that TdT expression can precede T gamma and T beta rearrangement during T ly

APA, Harvard, Vancouver, ISO, and other styles

20

Candon, Sophie, Blandine Rammaert, Anne Perrine Foray, et al. "Chronic Disseminated Candidiasis During Hematological Malignancies: An Immune Reconstitution Inflammatory Syndrome With Expansion of Pathogen-Specific T Helper Type 1 Cells." Journal of Infectious Diseases 221, no. 11 (2019): 1907–16. http://dx.doi.org/10.1093/infdis/jiz688.

Full text

Abstract:

Abstract Background Chronic disseminated candidiasis (CDC) is a rare disease that mostly occurs after chemotherapy-induced prolonged neutropenia in patients with hematological malignancies. It is believed to ensue from Candida colonization, breach of the intestinal epithelial barrier, and venous translocation to organs. Fungal blood or liver biopsy cultures are generally negative, suggesting the absence of an ongoing invasive fungal disease. Methods To unravel the contribution of the immune system to CDC pathogenesis, we undertook a prospective multicentric exploratory study in 44 CDC patients

APA, Harvard, Vancouver, ISO, and other styles

21

Terstappen, LW, S. Huang, and LJ Picker. "Flow cytometric assessment of human T-cell differentiation in thymus and bone marrow." Blood 79, no. 3 (1992): 666–77. http://dx.doi.org/10.1182/blood.v79.3.666.bloodjournal793666.

Full text

Abstract:

Using multidimensional flow cytometry we have defined and quantified the human T-cell differentiation pathway, focusing on those events occurring among the most immature thymocytes and putative bone marrow (BM) T-precursors. Early thymocytes were found to express the CD34 antigen and consisted of a mean 1.2% of cells within human pediatric (n = 9) and 2.0% in fetal thymi (n = 4). All CD34+ thymocytes were atypical blast by morphology, expressed intracytoplasmatic, but not cell surface, CD3, and were cell surface CD2+, CD5+, CD7+, CD38+, CD45+, CD45RA+, CD49d+, and LECAM-1(Leu8)high. CD34high t

APA, Harvard, Vancouver, ISO, and other styles

22

Meng, Chuang, Jun Liu, Xilong Kang, et al. "Discrepancy in Response of Mouse Dendritic Cells against BCG: Weak Immune Effects of Plasmacytoid Dendritic Cells Compared to Classical Dendritic Cells despite the Uptake of Bacilli." Tropical Medicine and Infectious Disease 8, no. 3 (2023): 140. http://dx.doi.org/10.3390/tropicalmed8030140.

Full text

Abstract:

Tuberculosis (TB), a zoonosis characterized by chronic respiratory infections, is mainly caused by Mycobacterium tuberculosis and is associated with one of the heaviest disease burdens in the world. Dendritic cells (DCs) play a key role and act as a bridge between innate and adaptive immune responses against TB. DCs are divided into distinct subsets. Currently, the response of DCs to mycobacterial infections is poorly understood. Herein, we aimed to evaluate the responses of splenic conventional DCs (cDC) and plasmacytoid DCs (pDC), subsets to Bacillus Calmette–Guérin (BCG) infection in mice.

APA, Harvard, Vancouver, ISO, and other styles

23

Maroof, Asher, and Paul M. Kaye. "Temporal Regulation of Interleukin-12p70 (IL-12p70) and IL-12-Related Cytokines in Splenic Dendritic Cell Subsets during Leishmania donovani Infection." Infection and Immunity 76, no. 1 (2007): 239–49. http://dx.doi.org/10.1128/iai.00643-07.

Full text

Abstract:

ABSTRACT Dendritic cells (DC) play an essential role in initiating and directing T-cell responses, in part by production of interleukin-12p70 (IL-12p70), IL-23, and IL-27. However, comparative studies on the capacity for cytokine production of DC subsets are rare. Here, we compare splenic CD8α+, CD4+, and double-negative (DN) DC, isolated 5 h to 28 days after Leishmania donovani infection, for (i) production of IL-12p70, (ii) accumulation of IL-12/23p40, IL-12p35, IL-23p19, and IL-27p28 mRNAs, and (iii) their capacity to direct CD4+ T-cell differentiation. At 5 h, conventional DC (cDC) accumul

APA, Harvard, Vancouver, ISO, and other styles

24

Nicolau, José Eduardo, Gil Benard, Luis Augusto Marcondes Fonseca, et al. "HIV heterosexual transmission to stable sexual partners of HIV-infected Brazilian hemophiliacs." Sao Paulo Medical Journal 114, no. 3 (1996): 1186–89. http://dx.doi.org/10.1590/s1516-31801996000300008.

Full text

Abstract:

Nineteen Brazilian HIV-infected hemophiliacs and their stable heterosexual sexual partners were studied with the aim of assessing the rate of HIV transmission in this at risk group. The mean length of relationship between couples was 7.4 years. The hemophiliac men were Class II (n=6), III (n=11) and IVa (n=2) of the CDC classification. They had decreased CD4+ and elevated CD8+ cell numbers; five had p24 antigenemia. We found 3 HIV-infected women (15.8 percent) by routine and confirmatory tests, a prevalence similar to that seen in other countries. They were asymptomatic and had no detectable p

APA, Harvard, Vancouver, ISO, and other styles

25

Balasubramaniam, Thara, Clive Carter, Marie von Lilienfeld-Toal, Paul Evans, Maria Helena Gilleece, and Gordon Cook. "Delayed Donor B-Cell Reconstitution After Allogeneic Stem Cell Transplantation Is Associated with Increased Risk of Relapse but Protects From Chronic Graft Versus Host Disease." Blood 114, no. 22 (2009): 2228. http://dx.doi.org/10.1182/blood.v114.22.2228.2228.

Full text

Abstract:

Abstract Abstract 2228 Poster Board II-205 B lymphocyte homeostasis may have a role in regulating the immune response, both stimulatory & regulatory/tolerogenic, in Allogeneic Stem Cell Transplantation (AlloSCT). The predictive relationship of donor B-cell reconstitution with relapse risk, chronic Graft versus Host Disease (cGvHD) & overall survival (OS) was investigated. We performed prospective comprehensive immune reconstitution studies in 71 patients undergoing AlloSCT (Matched Related Donor=33, Matched Unrelated Donor =34, Umbilical Cord Blood =3, Haplo-identical Related Donor =1)

APA, Harvard, Vancouver, ISO, and other styles

26

Von Stackelberg, A., and K. I. Romanova. "Role of monoclonal antibodies in therapy of lymphoproliferative disorders." Pediatric Hematology/Oncology and Immunopathology 14, no. 2 (2015): 20–37. https://doi.org/10.24287/1726-1708-2015-14-2-20-37.

Full text

Abstract:

The development of monoclonal antibodies (mAbs) for the treatment of hematological malignancies is in the focus of modern research. Several antibodies (Abs) effective in the treatment of acute lymphoblastic leukemia (ALL) in children are used at present. Nonconjugated humanized Abs are well tolerated and can be combined with chemotherapy, while immunoconjugats (with a second molecule - toxin, radioisotope, or label), delivering toxic compounds directly to the target cells, are fraught with serious side effects. Antigens with high selective expression on pathological cells are the ideal targets

APA, Harvard, Vancouver, ISO, and other styles

27

Hori, T., and H. Spits. "Clonal analysis of human CD4-CD8-CD3- thymocytes highly purified from postnatal thymus." Journal of Immunology 146, no. 7 (1991): 2116–21. http://dx.doi.org/10.4049/jimmunol.146.7.2116.

Full text

Abstract:

Abstract Human triple-negative (CD4-CD8-CD3-) thymocytes purified from postnatal thymus by the use of magnetic bead columns and cell sorting were cultured in bulk or cloned with a feeder cell mixture of irradiated PBL, irradiated JY cells, and PHA. Triple-negative thymocytes proliferated well under these culture conditions, and after 12 days in bulk culture they remained triple negative. Limiting dilution experiments revealed that the frequency of clonogenic cells in fresh triple-negative thymocytes was less than 1%. Of 40 clones obtained in a representative experiment, 37 were triple negative

APA, Harvard, Vancouver, ISO, and other styles

28

Park, Sang Chul, Tae-Gyun Kim, Hyung-Ju Cho, Chang-Hoon Kim, and Joo-Heon Yoon. "Reduced BDCA3+ dendritic cells in nasal mucosa induce severe inflammation in patients with allergic rhinitis and chronic rhinosinusitis." Journal of Immunology 204, no. 1_Supplement (2020): 147.12. http://dx.doi.org/10.4049/jimmunol.204.supp.147.12.

Full text

Abstract:

Abstract Dendritic cells (DCs) are specialized antigen-presenting cells that play a crucial role in T helper (Th) cell differentiation. DCs of human airway comprise conventional DCs (cDCs) and plasmacytoid DCs (pDCs), of which the cDCs lineage consists of cDC type 1 (cDC1) and cDC type 2 (cDC2). These DCs subsets differ in ontogeny and functional properties in immune response. Thus, we aimed to evaluate the expression of different dendritic cell subsets in nasal mucosa of patients with allergic rhinitis (AR) and chronic rhinosinusitis (CRS). Nasal polyp tissues or ethmoid mucosa from patients

APA, Harvard, Vancouver, ISO, and other styles

29

Terstappen, LW, S. Huang, and LJ Picker. "Flow cytometric assessment of human T-cell differentiation in thymus and bone marrow." Blood 79, no. 3 (1992): 666–77. http://dx.doi.org/10.1182/blood.v79.3.666.666.

Full text

Abstract:

Abstract Using multidimensional flow cytometry we have defined and quantified the human T-cell differentiation pathway, focusing on those events occurring among the most immature thymocytes and putative bone marrow (BM) T-precursors. Early thymocytes were found to express the CD34 antigen and consisted of a mean 1.2% of cells within human pediatric (n = 9) and 2.0% in fetal thymi (n = 4). All CD34+ thymocytes were atypical blast by morphology, expressed intracytoplasmatic, but not cell surface, CD3, and were cell surface CD2+, CD5+, CD7+, CD38+, CD45+, CD45RA+, CD49d+, and LECAM-1(Leu8)high. C

APA, Harvard, Vancouver, ISO, and other styles

30

Tessari, Anna, Isabella Testa, Elena Verzoni, et al. "Gene-expression profiling of collecting duct carcinoma of the kidney." Journal of Clinical Oncology 34, no. 2_suppl (2016): 540. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.540.

Full text

Abstract:

540 Background: Collecting duct carcinoma (CDC) of the kidney is a rare tumor, originating from renal medulla, characterized by younger age at diagnosis and poor prognosis. Since targeted therapies are currently not available for CDC, we aimed to identify the most deregulated pathways in this type of cancer to gain insights into new molecular targets. Methods: Total RNA was extracted from FFPE samples of primary CDC (n=9), clear cell carcinoma (CCC, n=7) and healthy normal (n=7) adjacent renal tissues (23 total samples). Gene expression profile was performed by GeneChip Human Transcriptome Arr

APA, Harvard, Vancouver, ISO, and other styles

31

Tamiolakis, Demetrio, Ioannis Venizelos, Athanasia Kotini, Sylva Nikolaidou, and Nikolaos Papadopoulos. "Prevalence of CD8/CD4 Ratio in the Fetal Thymic Parenchyme in Down’s Syndrome." Acta Medica (Hradec Kralove, Czech Republic) 46, no. 4 (2003): 179–82. http://dx.doi.org/10.14712/18059694.2019.30.

Full text

Abstract:

Aim: The maturation of most T- lymphocyte precursors takes place within the meshwork of thymic epithelial cells. Different steps of this process can be defined by immunologic phenotyping. The prothymocytes are positive for the terminal deoxynucleotidyl transferase (TdT) and give rise to cortical thymocytes, which express CD1, CD2, CD3, CD5, and both CD4 and CD8. These CD4 and CD8 double-positive cortical thymocytes differentiate into two lineages: CD4+ or CD8+ lymphocytes of the thymic medulla, by the tenth week of gestation. Our study points towards the determination of the CD8 cytotoxic/supp

APA, Harvard, Vancouver, ISO, and other styles

32

Stadnisky, Michael, Xuefang Xie, Ebony Coats, Timothy Bullock, and Michael Brown. "Self MHC class I licensed NK cells enhance adaptive CD8 T cell viral immunity (154.5)." Journal of Immunology 186, no. 1_Supplement (2011): 154.5. http://dx.doi.org/10.4049/jimmunol.186.supp.154.5.

Full text

Abstract:

Abstract MHC class I (MHC I) is essential to NK and T cell effector and surveillance functions. However, it is unknown if MHC I polymorphism influences adaptive immunity through NK cells. Previously, we found that MHC I Dk, a cognate ligand for the Ly49G2 inhibitory receptor, was essential to NK control of murine (M)CMV infection. Here we assessed the significance of NK inhibitory receptor recognition of MCMV on CD8 T cells in genetically defined MHC I Dk disparate mice. We observed that Dk-licensed Ly49G2+ NK cells stabilized and then enhanced conventional dendritic cells (cDC) recovery follo

APA, Harvard, Vancouver, ISO, and other styles

33

Miranda, Paulo Sérgio C., Andrés Marco, Joan Arthur Caylà, Hernando Galdós-Tangüis, and Patricia García de Olalla. "Validation of four AIDS-case definitions in HIV-infected intravenous drug users in Barcelona, Spain." Revista Brasileira de Epidemiologia 1, no. 2 (1998): 170–76. http://dx.doi.org/10.1590/s1415-790x1998000200007.

Full text

Abstract:

The objective of the study is to assess the sensitivity and specificity of four epidemiological AIDS-Case Definitions (CDC-87, CDC-93, Europe-93 and Revised Caracas) in HIV-infected intravenous drug users (IDU). The authors carried out a cross-sectional study with 136 IDUs, HIV-infected from a Men Penitentiary Center and from a drug addiction treatment center of Barcelona, Spain, between October/93 and April/94. A protocol, including demographic, clinical and laboratory variables was used by one doctor and the laboratory tests were done in the same institution. After that, the patients were cl

APA, Harvard, Vancouver, ISO, and other styles

34

Ribeiro, Camila Bastos, Jéssica Cristina dos Santos, Jacyelle Medeiros Silva та ін. "Crotalus durissus collilineatus Venom Induces TNF-α and IL-10 Production in Human Peripheral Blood Mononuclear Cells". ISRN Inflammation 2014 (19 січня 2014): 1–7. http://dx.doi.org/10.1155/2014/563628.

Full text

Abstract:

Snake venom has been the subject of numerous studies in an attempt to find properties and biological effects that may be beneficial to man. In this study we evaluated in vitro the effects of Crotalus durissus terrificus (Cdt) and Crotalus durissus collilineatus (Cdc) venom in human peripheral blood mononuclear cells (PBMCs). At 24 h, a significant decrease of viable cells was observed in cells stimulated with the Cdc venom at 0.0005 mg/mL and 0.005 mg/mL compared to the negative control. At 48 h, a significant decrease of viable cells was observed only in cells stimulated with Cdc venom at 0.0

APA, Harvard, Vancouver, ISO, and other styles

35

Reddy, A. C., and K. S. Reddy. "Pediatric Patient With Neurological And Leukemic Peripheral Blood Involvement By Small Cell Variant Of ALK- Positive Anaplastic Large Cell Lymphoma (ALCL): Case Study." American Journal of Clinical Pathology 154, Supplement_1 (2020): S113—S114. http://dx.doi.org/10.1093/ajcp/aqaa161.248.

Full text

Abstract:

Abstract Casestudy Anaplastic large cell lymphoma (ALCL), is a T-cell lymphoma typically consisting of large lymphoid cells including characteristic horseshoe- shaped hallmark cells. The rare small cell morphological variant of ALCL may pose a challenge in diagnosis, especially when the initial presentation is unusual. Results Our patient, a 7-year-old girl presented with a headache. A complete blood count showed leukocytosis and anemia. The smear was reported to have segmented neutrophils, reactive lymphocytes, and monocytes. A spinal tap was performed and flow analysis identified a minute ab

APA, Harvard, Vancouver, ISO, and other styles

36

Bertho, JM, MD Mossalayi, AH Dalloul, G. Mouterde, and P. Debre. "Isolation of an early T-cell precursor (CFU-TL) from human bone marrow." Blood 75, no. 5 (1990): 1064–68. http://dx.doi.org/10.1182/blood.v75.5.1064.1064.

Full text

Abstract:

Abstract CD2-CD3-CD4-CD8- human bone marrow (BM) cells were previously shown to generate T-cell clones in vitro. This capacity was abolished after treatment of this population with anti-CD7 monoclonal antibody and complement. In this study, using rosetting with sheep erythrocytes, complement-dependent cytotoxicity, and specific immunoadherence method, we isolated a minor BM subset that contained more than 80% CD7+CD2-CD3- CD4-CD8- cells with small lymphoid cell morphology. They comprised most early T-cell precursors (CFU-TL) as they displayed high capacity to generate T-cell clones when cultur

APA, Harvard, Vancouver, ISO, and other styles

37

Bertho, JM, MD Mossalayi, AH Dalloul, G. Mouterde, and P. Debre. "Isolation of an early T-cell precursor (CFU-TL) from human bone marrow." Blood 75, no. 5 (1990): 1064–68. http://dx.doi.org/10.1182/blood.v75.5.1064.bloodjournal7551064.

Full text

Abstract:

CD2-CD3-CD4-CD8- human bone marrow (BM) cells were previously shown to generate T-cell clones in vitro. This capacity was abolished after treatment of this population with anti-CD7 monoclonal antibody and complement. In this study, using rosetting with sheep erythrocytes, complement-dependent cytotoxicity, and specific immunoadherence method, we isolated a minor BM subset that contained more than 80% CD7+CD2-CD3- CD4-CD8- cells with small lymphoid cell morphology. They comprised most early T-cell precursors (CFU-TL) as they displayed high capacity to generate T-cell clones when cultured in lim

APA, Harvard, Vancouver, ISO, and other styles

38

&NA;. "CDC." Oncology Times 25, no. 12 (2003): 20–21. http://dx.doi.org/10.1097/01.cot.0000289827.16457.1d.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

STUMP, ELIZABETH. "CDC." Neurology Today 8, no. 16 (2008): 20. http://dx.doi.org/10.1097/01.nt.0000337662.75151.23.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Ellis, Fay. "CDC." Neurology Today 12, no. 22 (2012): 13. http://dx.doi.org/10.1097/01.nt.0000423167.85335.bf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Shaheen, M., L. Warmke, and M. Nassiri. "Focal Myositis with CD8+T-Cell predominance: an Inflammatory Myositis Mimicking a Soft Tissue Neoplasm." American Journal of Clinical Pathology 158, Supplement_1 (2022): S109. http://dx.doi.org/10.1093/ajcp/aqac126.231.

Full text

Abstract:

Abstract Introduction/Objective FM is a rare self-limiting T-cell rich lesion arising within muscles of young adults as a solitary lesion and can be confused with a variety of neoplastic/inflammatory conditions or lymphoma. Here we describe a rare T-cell rich variant of FM with CD8 predominance. Methods/Case Report A 51-year-old female presented with two-month history of left trapezius swelling. MRI showed an enhancing tumor within the muscle, suspicious of sarcoma, less likely myeloma. Results (if a Case Study enter NA) Biopsy showed diffuse infiltration of small lymphocytes in a fibrotic bac

APA, Harvard, Vancouver, ISO, and other styles

42

Komolafe, O. O., M. B. Adewole, and O. J. Matthew. "Assessment of Different Biochar and Composted Cow Dung on Soil Properties, Growth and Cob Weight of Maize." Journal of Tropical Crop Science 9, no. 02 (2022): 124–36. http://dx.doi.org/10.29244/jtcs.9.02.124-136.

Full text

Abstract:

Crop production in tropical soils is constrained by low fertility. The scarcity and high prices of chemical fertilizers have added to the existing challenges. This study examined the influence of different types of biochar and cow dung compost (CDC) on soil properties, growth and cob weight of maize. A polythene pot experiment was conducted at the screen house of the Institute of Ecology, Obafemi Awolowo University, Ile-Ife, Nigeria. The experiment was laid out in a completely randomized design. Amendments used were: cow dung compost, cow dung biochar and maize cob biochar, which were applied

APA, Harvard, Vancouver, ISO, and other styles

43

Araujo, Maria das Graças Pereira, Victor lima Soares, Alessandra Suelen Jardim Silva, et al. "Importance of Flow Cytometry in the Diagnosis of Sezary Syndrome in the State of Rio Grande Do Norte, Brazil." Blood 136, Supplement 1 (2020): 39–40. http://dx.doi.org/10.1182/blood-2020-143378.

Full text

Abstract:

Introduction:Sézary Syndrome (SS) is a leukemic form of Fungal Mycosis (FM), a rare form of T-cell lymphoma, characterized by erythroderma, generalized lymphadenopathy and infiltration of neoplastic T cells (Sézary cells) with cerebriform nucleus on the skin, lymph nodes and peripheral blood, being observed predominantly in men and individuals over the age of 60 and black. In the diagnosis of SS / FM, at least one of the criteria must be observed: minimum absolute Sézary cells count of 1000/mm3, expansion of TCD4+ cells with a ratio CD4/CD8 &gt;10, loss of at least one mature T cell antige

APA, Harvard, Vancouver, ISO, and other styles

44

Diao, Jun, Jun Zhao, Anastassia Mikhailova, and Mark Cattral. "Identification of a novel immunosuppressive DC subpopulation in tolerized heart allografts (145.23)." Journal of Immunology 184, no. 1_Supplement (2010): 145.23. http://dx.doi.org/10.4049/jimmunol.184.supp.145.23.

Full text

Abstract:

Abstract The role of dendritic cells (DC) in the maintenance of allograft tolerance is unclear. We analyzed the composition and function of DC infiltrates in tolerized murine heart allografts. Methods. B6 donor splenocytes (Day -7) plus anti-CD4 antibody (Day -1, 2 5 and 7) were injected into BALB/c recipients of B6 heart allografts; mice with heart grafts beating &gt; 80 days were considered tolerant. Syngenic heart grafts (B6 to B6) were used as control. Results: We found that graft-infiltrating Lin-CD11c+MHCII+ cDC contained a novel Gr-1+ cDC subpopulation. B220+CD11c+MHCII+ plasmacytoi

APA, Harvard, Vancouver, ISO, and other styles

45

Rasmussen, R. A., S. L. Counts, J. F. Daley, and S. F. Schlossman. "Isolation and characterization of CD6- T cells from peripheral blood." Journal of Immunology 152, no. 2 (1994): 527–36. http://dx.doi.org/10.4049/jimmunol.152.2.527.

Full text

Abstract:

Abstract Antibodies to the CD6 Ag have been described as having pan-T cell reactivity. We have recently demonstrated, however, that after treatment of PBL with an anti-CD6-blocked ricin-conjugated immunotoxin, clonal populations of CD3+, CD6- cells can be identified. Herein we show that through dual parameter staining of freshly isolated E-rosette+ cells, an average of 5 to 6% of either CD3+ or CD5+ cells express little or no CD6 on their surface. After negative selection by antibody-coated paramagnetic bead depletion, expanded CD6- T cells were shown to be CD1a-, CD2+, CD3+, CD5+, CD16-, CD56

APA, Harvard, Vancouver, ISO, and other styles

46

Smolyannikova, V. A., A. E. Karamova, A. A. Vorontsova, L. F. Znamenskaya, M. A. Nefedova, and K. M. Aulova. "Problems in differential diagnosis of mycosis fungoides and psoriasis: comparison of clinical and morphological features." CLINICAL AND EXPERIMENTAL MORPHOLOGY 11, no. 3 (2022): 73–80. http://dx.doi.org/10.31088/cem2022.11.3.73-80.

Full text

Abstract:

Mycosis fungoides is an epidermotropic primary cutaneous T-cell lymphoma, represented com-posed of small and medium-sized lymphocytes with cerebriform nuclei. Differential diagnosis of cutaneous T-cell lymphoma and chronic autoimmune dermatoses, including psoriasis, may present significant chal-lenges in some cases. We analyzed three clinical cases of mycosis fungoides, in which psoriasis was initially diagnosed. Histological and immunohistochemical studies with a wide panel of antibodies (CD4 CD8, CD2, CD5, CD7, CD3) were performed, and monoclonal T-lymphocyte populations were determined with

APA, Harvard, Vancouver, ISO, and other styles

47

Hucl, Pierre, and Maria Matus-Cádiz. "CDC EMDR-4, CDC EMDR-9, and CDC EMDR-14 spring wheats." Canadian Journal of Plant Science 82, no. 2 (2002): 411–13. http://dx.doi.org/10.4141/p01-114.

Full text

Abstract:

Early-maturing spring wheat germplasm lines CDC EMDR-4, CDC EMDR-9, and CDC EMDR-14 have high levels of seed dormancy. Their agronomic performance is comparable to that of the cultivar Columbus. These three lines had similar grain protein concentration and kernel hardness relative to the check cultivars, except CDC EMDR-4, which had a soft endosperm texture. Key words: Triticum aestivum L., germplasm, seed dormancy, pre-harvest sprouting resistance

APA, Harvard, Vancouver, ISO, and other styles

48

Gao, Y., W. Wang, and L. Chen. "Uncommon Variant of CD4+ T-cell Large Granular Lymphocytic Leukemia." American Journal of Clinical Pathology 158, Supplement_1 (2022): S103—S104. http://dx.doi.org/10.1093/ajcp/aqac126.218.

Full text

Abstract:

Abstract Introduction/Objective T-cell large granular lymphocytic leukemia (T-LGL) is a T-cell lymphoma with persistently increased large granular lymphocytes in peripheral blood. The majority of T-LGL is associated with CD8+ T-cells. However, the CD4+ variant is uncommonly seen. Methods/Case Report The patient is a 49-year-old female with a history of diabetes mellites and anemia who presented with shortness of breath, lower extremities edema, and fatigue. Physical examination showed a significantly distended abdomen. CBC results showed hemoglobin 6.9 g/dL, WBC 18.2 × 109/L with 88% lymphocyt

APA, Harvard, Vancouver, ISO, and other styles

49

Granichin, O. N. "48th and 49th international conferences “decision and control” (IEEE CDC/CCC 2009 and CDC 2010)." Automation and Remote Control 72, no. 12 (2011): 2578–82. http://dx.doi.org/10.1134/s0005117911120125.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Damle, N. K., and L. V. Doyle. "Stimulation via the CD3 and CD28 molecules induces responsiveness to IL-4 in CD4+CD29+CD45R- memory T lymphocytes." Journal of Immunology 143, no. 6 (1989): 1761–67. http://dx.doi.org/10.4049/jimmunol.143.6.1761.

Full text

Abstract:

Abstract Although both IL-2 and IL-4 can promote the growth of activated T cells, IL-4 appears to selectively promote the growth of those helper/inducer and cytolytic T cells which have been activated via their CD3/TCR complex. The present study examines the participation of CD28 and certain other T cell-surface molecules in inducing T cell responsiveness to IL-4. Purified small high density T cells were cultured in the absence of accessory cells with various soluble anti-human T cell mAb with or without soluble anti-CD3 mAb and their responsiveness to IL-4 was studied. None of the soluble ant

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!