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Journal articles on the topic 'Cedar resin'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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1

Ramzy, Hamed, Kazzi Yolla, and Awada Houssein. "Phenolic Foam Reinforced by Cedar's Resin." Chemical Science International Journal 19, no. 1 (2017): 1–6. https://doi.org/10.9734/CSIJ/2017/33377.

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Recently phenolic foams have been received much attention because of their excellent properties including flame resistance, low density, high thermal stability over a broad temperature range and low generation of toxic gases during combustion. Cedar resin was used as a toughening agent to modify the brittleness of phenolic foam. The cedar resin was first introduced to the phenol formaldehyde resin. The mixture was successfully used to prepare phenolic foam using appropriate combinations of flowing agent. Benzene Sulfonic acid was employed as a curing agent. Orthophosphoric acid and nonionic su
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2

De Moraes Gomes Pereira, Maria Aparecida, Maria José Alves de Oliveira, Larissa Otubo, Vagner Fernandes, and Pablo Antônio Salvador Vasquez. "Restoration of culturally significant wooden artifacts using gamma radiation curable polyester resins." Brazilian Journal of Radiation Sciences 12, no. 4A (Suppl.) (2025): e2653. https://doi.org/10.15392/2319-0612.2024.2653.

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The preservation of cultural artifacts, particularly those made of wood, is a significant concern for conservators due to their susceptibility to damage from xylophagous organisms, fungi, and bacteria. This study investigates the use of gamma radiation to cure polymeric resins for the consolidation of three wood species: cedar (Cedrela spp.), canafistula (Peltophorum dubium), and ivorywood (Balfourodendron riedelianum). Various resins, including polyester LP 8847® combined with styrene, were subjected to gamma radiation to induce cross-linking without the need for catalysts. The results demons
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3

Скаковский, Е. Д., Л. Ю. Тычинская, Е. Г. Попов та ін. "ЯМР-анализ состава живицы кедровых сосен". Известия СПбЛТА, № 253 (18 червня 2025): 260–81. https://doi.org/10.21266/2079-4304.2025.253.260-281.

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Кедровые сосны относятся к подроду Strobus и являются особо хозяйственно ценной группой хвойных растений не только из-за древесины, но также благодаря полезным компонентам их живиц, химический состав которых изучен далеко не достаточно. Нами проведен сравнительный количественный анализ состава живиц кедровых сосен, взятых от разных деревьев сосны кедровой корейской (Pinus koraiensis Siebold & Zucc.), кедровых сосен европейской (P. cembra L.) и сибирской (P. sibirica Du Tour), а также сосны кедровой стланиковой (Pinus pumila (Pall.) Regel). Для этого мы использовали метод ЯМР-спектроско
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4

Messier, Christian, and James P. Kimmins. "Growth of western red cedar seedlings in relation to microtopography, forest floor nutrient status, and fireweed and salal on clear-cut sites in coastal British Columbia." Canadian Journal of Forest Research 22, no. 3 (1992): 273–78. http://dx.doi.org/10.1139/x92-036.

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The growth of western red cedar (Thujaplicata Donn) seedlings was studied in relation to microtopography, to forest floor nutrient status, and to fireweed (Epilobiumangustifolium L.) and salal (Gaultheriashallon Pursh) abundance on 4-year-old logged and burned sites dominated by salal on northern Vancouver Island, British Columbia. These relationships were sought to determine some possible factors at the microsite level that influence the growth of western red cedar on recently clear-cut sites. Western red cedar growth and fireweed abundance and height were significantly greater in depressions
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Tillman-Sutela, Eila, and Anneli Kauppi. "Structures restricting passage of water in the mature seeds of yellow-cedar (Chamaecyparis nootkatensis)." Canadian Journal of Botany 76, no. 8 (1998): 1458–66. http://dx.doi.org/10.1139/b98-135.

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Anatomical structures of seed surface layers and their role in impeding passage of water were studied for mature yellow-cedar (Chamaecyparis nootkatensis D. Don) seeds. The structures of the seed coat, nucellar layers, and megagametophyte of both dry and moistened, sectioned seeds were examined with a field emission scanning electron microscope. The anatomical details of resin-embedded seeds were studied by light or fluorescence microscopy using stained and unstained sections. The permeability of the structures exterior to the megagametophyte was analyzed by placing seeds in a Methylene Blue s
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6

Ono, Kenta, Osamu Tanaike, Ryo Ishii, et al. "Solvent-Free Fabrication of an Elastomeric Epoxy Resin Using Glycol Lignin from Japanese Cedar." ACS Omega 4, no. 17 (2019): 17251–56. http://dx.doi.org/10.1021/acsomega.9b01884.

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7

Bhardwaj, Vibha. "Deodar Cedar (Cedrus Deodara): Efficacy for Potential of Secondary Metabolites and Antibacterial Activity." Biomedical Research and Clinical Reviews 6, no. 5 (2022): 01–09. http://dx.doi.org/10.31579/2692-9406/111.

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The setback of microbial resistance is growing and the use of antimicrobial drugs in the future is still uncertain. Infectious diseases are accountable for millions of global deaths annually. Therefore, necessary steps need to be taken to reduce this problem. In the present study, crude extracts of leaves, bark and resins of Cedrus deodara in methanol was investigated for secondary metabolites (flavonoids, glycosides, phenols, saponins, tannins, terpenoids) and antibacterial effect of Cedrus deodara was evaluated on multidrug resistant (MDR) strains of Bacillus subtilis (ATCC 6633), E. coli (A
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8

Lee, Yun-Yun, Wen-Jau Lee, Ling-Ying Hsu, and Han-Min Hsieh. "Properties of molding plates made with various matrices impregnated with PF and liquefied wood-based PF resins." Holzforschung 68, no. 1 (2014): 37–43. http://dx.doi.org/10.1515/hf-2013-0029.

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Abstract Phenol (P) and phenol-liquefied wood (LW; Cryptomeria japonica, Japanese cedar) have been reacted with formalin and ammonium hydroxide as a catalyst to prepare alcohol-soluble phenol-formaldehyde (PF) resins named PF and LWPF, respectively. The resins prepared were dehydrated, diluted with ethanol, and impregnated into wood powders, filter papers, and cloths. The PF resin-impregnated matrix materials were then hot-pressed to form molding plates (MP) and their properties were tested. Differential scanning calorimetric (DSC) analysis shows that both PF and LWPF behave as hot-melting res
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9

KURIMOTO, Yasuji, Hidefumi YAMAUCHI, Takanobu SASAKI, and Satoru KANETAKA. "PRODUCTION AND APPLICATION OF WOOD-POLYURETHANE RESIN COMPOSITES USING STUBS AND ROOTS OF JAPANESE CEDAR." ENVIRONMENTAL SYSTEMS RESEARCH 34 (2006): 585–90. http://dx.doi.org/10.2208/proer.34.585.

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10

Jia, Chong, Yang Zhang, Juqing Cui, and Lu Gan. "The Antibacterial Properties and Safety of a Nanoparticle-Coated Parquet Floor." Coatings 9, no. 6 (2019): 403. http://dx.doi.org/10.3390/coatings9060403.

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Floor antibacterial technology prevents the human body from cross-infection with bacterial diseases. The most commonly used approach to endow daily-used floors with antibacterial properties is to apply a thin film of antibacterial agents on the parquet floor surface. In the present study, five commercial antibacterial nanoparticles were first dispersed in melamine resin solution, and then applied on a floor. Afterwards, the antibacterial properties of the nanoparticle-coated floor were investigated, in which Escherichia coli was used as the target bacteria. The impact of the nanoparticle dispe
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11

B, Purevsuren, Davaajav Ya, Batbileg S, et al. "Investigation on pyrolysis of some organic raw materials." Mongolian Journal of Chemistry 17, no. 43 (2017): 5–13. http://dx.doi.org/10.5564/mjc.v17i43.739.

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We have been working on pyrolysis of some organic raw materials including different rank coals, oil shale, wood waste, animal bone, cedar shell, polypropylene waste, milk casein and characterization of obtained hard residue, tar and pyrolytic water and gas after pyrolysis. The technical characteristics of these organic raw materials have been determined and the thermal stability characteristics such as thermal stability indices (T5% and T25%) determined by using thermogravimetric analysis. The pyrolysis experiments were performed at different heating temperatures and the yields of hard residue
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12

Lyggitsou, Georgia, Christina Barda, Maria Anagnostou, et al. "Wound Healing Potential of Herbal Hydrogel Formulations of Cedrus brevifolia Extracts in Mice." Gels 10, no. 11 (2024): 750. http://dx.doi.org/10.3390/gels10110750.

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Wound healing stands as a paramount therapeutic pursuit, imposing significant challenges on healthcare, particularly for vulnerable populations. Cedrus brevifolia, a species endemic to Cyprus, thrives in the Tripylos region, commonly known as Cedar Valley, within the Paphos forest. Despite its endemism, this species exhibits negligible genetic divergence from its Mediterranean related species. This study aims to investigate the potential of C. brevifolia resin and bark extracts in promoting wound healing in a mouse model. Previous in vitro investigations have elucidated the antioxidant and ant
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13

SANUI, Takayoshi, and Junichi YUKAWA. "A New Gall Midge of the Genus Resseliella (Diptera : Cecidomyiidae) Inhabiting Resin of the Japanese Cedar, Cryptomeria japonica (Taxodiaceae)." Applied Entomology and Zoology 20, no. 1 (1985): 27–33. http://dx.doi.org/10.1303/aez.20.27.

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14

林伊涵, 林伊涵, та 林慶元 Yi-Han Lin. "國產材製成直交集成板之防火性能初探". 建築學報 118-1, № 118-1 (2021): 049–59. http://dx.doi.org/10.53106/101632122021120118010.

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<p>由於目前臺灣直交集成板（Cross-Laminated-Timber, CLT）大多為國外預製進口，若能直接運用國內生產木材，不旦可活絡國產材的市場，亦能輔助臺灣國產材製成CLT法規的推動。故本研究以國產材CLT進行耐火試驗初探，參考CNS12514-1「建築物構造部分之耐火試驗法」標準進行耐火試驗，以小尺寸45cm×45cm進行試驗，每次試驗為2至4片放入特製鐵框中以垂直(等同於牆)方向進行加熱，共加熱試驗6組總計20個試驗體。其中變數條件為三種國產材（柳杉Japanese cedar、臺灣杉Taiwania,及杉木China fir）、兩種膠合劑（間苯二酚樹脂膠合劑RF及乙烯脲酯膠合劑KR）及三種樹種強度（M30、M60及M90）分別進行30分鐘與60分鐘之耐火試驗。綜合變數條件及試體炭化深度比較，結果如下：1.柳杉為三種樹種中炭化深度最少之樹種。2.強度M30、M60及M90之平均炭化速率分別為0.67 mm/min、0.72 mm/min及0.79 mm/min，本實驗結果為等級越高有提高炭化速率的趨勢。3.膠合劑不同炭化深度較無差別，但膠合效果以間苯二酚樹脂為佳。</p> <p> </p><p>At present, cross-laminated-timber (CL
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15

Chien, Tsai-Po, Te-Hsin Yang, and Feng-Cheng Chang. "Flexural Performance of Built-Up Beams Made with Plantation Wood." Forests 10, no. 8 (2019): 647. http://dx.doi.org/10.3390/f10080647.

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In this study, Japanese cedar (Cryptomeria japonica (L. f.) D. Don) harvested from a plantation in Taiwan was used to develop built-up beams using self-tapping screws as metal connectors and resorcinol formaldehyde resin as glue to assemble components based on various assembly configurations. Results showed that adding glue provided flexural rigidity, whereas assembly using self-tapping screws resulted in built-up beams with high ductility but relatively low flexural bearing capacity. Beams used glue exhibited approximately linear behavior, whereas those using only screws exhibited some undula
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16

Sharonova, N. L., D. A. Terenzhev, A. P. Lyubina, I. D. Fadeeva, and A. T. Zakirov. "Substances for biological protection, regulation of growth and development of agricultural crops based on secondary plant metabolites." IOP Conference Series: Earth and Environmental Science 949, no. 1 (2022): 012049. http://dx.doi.org/10.1088/1755-1315/949/1/012049.

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Abstract Plants are a promising source of a wide range of biologically active substances as biopesticides and growth stimulants in organic agriculture. Screening of the antimicrobial activity of ethanol extracts of air-dry aboveground biomass of 22 plant species of the family Asteraceae, typical representatives of the flora of the Republic of Tatarstan, was carried out. The antibacterial activity of greater knapweed (Centaurea scabiosa L.), milk thistle (Silybum marianum (L.) Gaertn), scentless mayweed (Tripleurospermum inodorum (L.) Sch. Bip.), marsh cudweed (Gnaphalium uliginosum L.) against
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17

Khan, Muhammad Usman, Muhammad Abas, Sahar Noor, Bashir Salah, Waqas Saleem, and Razaullah Khan. "Experimental and Statistical Analysis of Saw Mill Wood Waste Composite Properties for Practical Applications." Polymers 13, no. 22 (2021): 4038. http://dx.doi.org/10.3390/polym13224038.

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The utilization of composite materials is increasing at a growing rate in almost all types of products, due to their strength-to-stiffness ratio. From this perspective, natural waste composites, i.e., wood waste composites, have also been investigated for their effective and sustainable employment. This paper deals with the application of hard and soft wood waste (i.e., acacia and cedar wood) with epoxy resin polymer to develop high strength and thermally stable wood composites. Mechanical (tensile, flexural, impact, and hardness) and thermal properties of samples are studied using Differentia
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18

Ito, Kensuke. "Spatial extent of traumatic resin duct induction in Japanese cedar, Cryptomeria japonica D. Don, following feeding damage by the cryptomeria bark borer, Semanotus japonicus Lacordaire (Coleoptera : Cerambycidae)." Applied Entomology and Zoology 33, no. 4 (1998): 561–66. http://dx.doi.org/10.1303/aez.33.561.

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19

Chang, Chia-Wei, Wei-Ling Kuo, and Kun-Tsung Lu. "On the Effect of Heat Treatments on the Adhesion, Finishing and Decay Resistance of Japanese cedar (Cryptomeria japonica D. Don) and Formosa acacia (Acacia confuse Merr.(Leguminosae))." Forests 10, no. 7 (2019): 586. http://dx.doi.org/10.3390/f10070586.

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In Taiwan, it is important to maintain sustainable development of the forestry industry in order to raise the self-sufficiency of domestic timber. Japanese cedar (Cryptomeria D. Don and Formosa acacia (Acacia confusa Merr.(Leguminosae)) have abundant storage options and are the potential candidates for this purpose. Heat treatment is a new environment-friendly method used to enhance the dimensional stability and durability of wood. On treatment, a surface with new characteristics is produced because of wood component changes. Consequently, an inactivated surface and a weak boundary layer are g
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VALEEV, F. A. "SYNTHESIS OF ELEUTHESIDES." Izvestia Ufimskogo Nauchnogo Tsentra RAN, no. 2 (June 10, 2024): 8–25. http://dx.doi.org/10.31040/2222-8349-2024-0-2-8-25.

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The review is devoted to research in the field of "marine" diterpene metabolites of the 4,7-oxaeunicellan type, which have a taxol-like mechanism of cytotoxic action. The known most effective chemical syntheses are presented, as well as the results of our own research, on the basis of which, based on (+)-δ-cadinol, the formal synthesis of eleuthesides was realized, and the synthesis of analogs of sorcrdictyin A and eleutherobin was carried out from the Diels-Alder adduct of levogluclsenone and piperylene. In the course of the research, the features of the chemical behavior of the little-studie
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21

Sahin, H. T. "Application of various solvent‐type alkyd resins to pine and cedar woods for achieving water repellence." Pigment & Resin Technology 37, no. 6 (2008): 395–401. http://dx.doi.org/10.1108/03699420810915094.

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22

Grosser, Dietger. "On the Occurrence of Trabeculae With Special Consideration of Diseased Trees." IAWA Journal 7, no. 4 (1986): 319–41. http://dx.doi.org/10.1163/22941932-90001003.

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Comprehensive investigations on trabeculae in softwoods have shown that they occur much more frequently than has hitherto generally been assumed. A systematic study oflarge series of microtome sections, i.e., transverse sections and particularly radial sections of extended annual ring sequences will, as a rule, give sufficient evidence for the occurrence of trabeculae and related structures. Apart from this phenomenon an increased occurrence of trabeculae was often found in the annual rings of healthy and diseased trees from forest decline areas from the middle of the 1970's onwards. Moreover,
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23

Ogawa, Keita, Satoshi Fukuta, and Kenji Kobayashi. "Embedment properties of Japanese cedar (Cryptomeria japonica) treated with resin impregnation." Journal of Wood Science 68, no. 1 (2022). http://dx.doi.org/10.1186/s10086-022-02018-5.

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AbstractTo strengthen the embedment properties of wood, this study applied the resin impregnation technique, which fills the resin into wood cells. The urethane prepolymer and acrylic monomer were selected in this study. A mechanical test by a round steel bar loaded to the wood specimen was conducted. The characteristics showed higher values in the resin-impregnated groups than in the control specimen group, especially in the stiffness. The urethane- and acryl-impregnated group showed 3.78 and 2.27 times the stiffness values of the control groups in the parallel-loaded condition, and 1.94 and
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24

Filippov, Dionis, Andrey Blinov, Alexey Gvozdenko, et al. "Hydrophobization of Silicon Dioxide Microspheres With Resin Acids of Natural Gums." Polymers for Advanced Technologies 36, no. 2 (2025). https://doi.org/10.1002/pat.70114.

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ABSTRACTCurrently, hydrophobic materials and coatings are of great practical interest due to their unique functional characteristics. The aim of this study was to develop a hydrophobic agent based on SiO2 microspheres hydrophobized with resin acids of natural gums to protect various surfaces. According to quantum chemical modeling, the most energetically advantageous interactions are those of SiO2 with birch gum and pine gum through the COO− group of dihydroabietinic acid (E = −1361.256 kcal/mol), and with cedar gum through COO− group of lambertianic acid (E = −1433.537 kcal/mol). Notably, the
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25

Wang, Xin, Bin Li, Dongyan Liu, et al. "Isolation, characterization, and LC MS/MS determination of anti-obesity components from pine needles of Cedrus deodara (Roxb.) G. Don." Frontiers in Nutrition 11 (August 1, 2024). http://dx.doi.org/10.3389/fnut.2024.1448908.

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ObjectiveThis study aimed to isolate and analyze the components in cedar pine needles (needle leaves of Cedrus deodara (Roxb.) G. Don) that exhibit anti-obesity effects, as determined through animal experiments.MethodsThe extract of cedar pine needles was separated into four fractions of different polarities using a macroporous resin column. The fraction that retained anti-obesity activity was evaluated based on the results of animal experiments. Monomeric compounds were structurally characterized and isolated from the active fraction using a preparative liquid chromatography system. Combined
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Sun, Minkai, Taisuke Nakashima, Yuri Yoshimura, et al. "Effects and interaction of different interior material treatment and personal preference on psychological and physiological responses in living environment." Journal of Wood Science 66, no. 1 (2020). http://dx.doi.org/10.1186/s10086-020-01910-2.

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Abstract Japanese cedar (Cryptomeria japonica) wood is widely used as a traditional construction material in Japan. The relationship between an individual’s perceived comfort level and a preference for Japanese cedar wood interiors is of interest. We compared volunteers’ physiological responses and subjective evaluations of wooden dwelling spaces with different wood materials: planed Japanese cedar lumber, or printed grain resin sheet overlay boards. Eighty-three subjects were asked to stay in each room for 30 min. We evaluated salivary stress markers, blood pressure, the profile of mood state
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Ogawa, Keita, Kenji Kobayashi, and Satoshi Fukuta. "Compression properties of Japanese cedar (Cryptomeria japonica) treated with resin impregnation under loading perpendicular to the grain." Journal of Wood Science 70, no. 1 (2024). http://dx.doi.org/10.1186/s10086-024-02142-4.

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AbstractThe compression properties of wood perpendicular to the grain is an important resistance mechanism in timber joints, especially wood-to-wood joints. Hence, improving the compression properties of wood is essential to developing timber joints with high resistance performance. In this study, we attempted to improve the compression properties using a resin impregnation technique. Three compression tests were conducted: loading at the full surface of the specimen, loading at the local part of the specimen with the unloaded part expanding in the tangential direction, and loading at the loca
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Lee, Wen-Jau, Chen-Ling Kang, Kuo-Chun Chang, and Yi-Chun Chen. "Synthesis and properties of resol-type phenol-formaldehyde resins prepared from H2SO4- and HCl-catalyzed phenol-liquefied Cryptomeria japonica wood." Holzforschung 66, no. 1 (2012). http://dx.doi.org/10.1515/hf.2011.121.

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Abstract Wood of Cryptomeria japonica (Japanese cedar) was liquefied in phenol with H2SO4 or HCl as catalysts and used as raw materials to prepare phenol-formaldehyde (PF) resins. The curing behavior and adhesion properties of resins prepared were investigated. Wood liquefied with H2SO4 as a catalyst had better liquefaction effect than that with HCl; however, the reaction of resin synthesis was hard to control due to its quickly increasing viscosity. Differential scanning calorimetry analysis shows that PF resins prepared from HCl-catalyzed liquefied wood had higher reactivity than those of H2
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Kosugi, Shun, Marina Totsuka, Hiroki Nakashima, Masakazu Ikeda, and Kenji Aoki. "Compressive behavior of wood contact with mortar and epoxy resin adhesives." European Journal of Wood and Wood Products 83, no. 3 (2025). https://doi.org/10.1007/s00107-025-02221-3.

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Abstract In recent years, researchers and engineers have developed a wide range of connection systems between wood and other materials, such as concrete and steel. However, the mechanical behavior of the surfaces where wood meets these materials is yet to be understood. In wood, low-stiffness areas called damage zones form near end grains, when compressed parallel to the grain. These low-stiffness areas may come in contact with various materials; therefore, understanding the behavior of the damage zones with various materials is important. This paper describes the results and analysis of exper
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Ogawa, Keita, Satoshi Fukuta, and Kenji Kobayashi. "Experimental study of lateral resistance of bolted joints using Japanese cedar (Cryptomeria japonica) treated with resin impregnation." Journal of Wood Science 66, no. 1 (2020). http://dx.doi.org/10.1186/s10086-020-01918-8.

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Abstract The development of wooden joints possessing high resistance performance has become an important issue for the construction of newer buildings. This study attempts to strengthen the lateral resistance of bolted joints using the previously reported plasticizing technique. This technique consists of two processing stages: incising the surface of the wood using an ultraviolet wavelength short-pulse laser and impregnating the resin into the incised area. This technique makes it possible to plasticize only a local part of the wood surface. Bolted joint specimens were assembled using plastic
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Okamoto, Tsuyoshi, Taisuke Nakashima, Kurniawan Eka Permana, et al. "Electrophysiological effects of Japanese cedarwood on sleep quality in humans." Journal of Wood Science 70, no. 1 (2024). http://dx.doi.org/10.1186/s10086-024-02150-4.

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AbstractSleep plays an important role in human health. Changes in the sleeping environment can affect sleep quality. The present study investigated the effects of natural wood on sleep quality. The interior material was a fully used Cryptomeria japonica wood board (Japanese cedar room), while the particleboard and medium-density fiberboard (MDF) were covered by a vinyl cloth with a woodgrain (resin room). In order to assess sleep quality, the sleep–depth index (SDI) is calculated based on the lengths of sleep stage 3 and the rapid eye movement (REM) stage using electroencephalography (EEG). Be
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32

Sahin, Halil Turgut, and Ismail Erbil. "A Study on Surface Physicochemical Properties of Woods Treated in Emulsion of Waterborne Varnish with Sesame and Grape Seed Oil." Asian Journal of Biotechnology and Bioresource Technology, March 27, 2021, 1–9. http://dx.doi.org/10.9734/ajb2t/2021/v7i130090.

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Aims: An eco-friendly coating emulsion prepared with mixture of oils of sesame and grape seed and alkyd-based waterborne varnish. The prepared emulsion applied four different wood substrates (walnut, beech, cedar and fir) in order to be investigated for some selected surface properties.
 Study Design: Several test methods were used to evaluate surface physicochemical properties of the coatings. The results obtained may be suggested for the selection of the best varnish-emulsion formulation for the improvement wood substrates and could provide useful evaluation of the test methods employed
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33

Schimanofsky, Corina, Andreas Petritz, Boyuan Ban, et al. "Natural Dielectrics for Organic Field Effect Transistors: A Study of Resins from Larch, Spruce and Atlas Cedar Pinaceae Trees." Materials Advances, 2025. https://doi.org/10.1039/d5ma00401b.

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Three pinaceae resins originating from trees of high industrial significance: European larch, European spruce, and Atlas cedar that were examined in this work exhibit exceptional film formation, great dielectric qualities,...
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34

Henley, Brandon Christian, Maureen Okafor, Ambar Kulshreshtha, Antoine Trammell, and Ihab Hajjar. "Effects of candesartan on cerebral microvascular function in mild cognitive impairment: Results of two clinical trials." International Journal of Stroke, January 16, 2023, 174749302311533. http://dx.doi.org/10.1177/17474930231153313.

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Background: Cerebral microvascular dysfunction is commonly seen in Alzheimer’s disease (AD) and vascular cognitive impairment (VCI). Cerebrovascular reactivity (CVR) to CO2 reflects cerebral microvascular health and may be modulated by the renin-angiotensin system (RAS). This study aimed to investigate the effects of RAS modulation on CVR in individuals with mild cognitive impairment (MCI) due to underlying vascular or AD etiologies. Methods: This study presents findings of candesartan’s effects on the secondary outcomes of two double-blind randomized clinical trials of 12-month therapy of can
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