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1

Chiarotto, James Anthony. Hypoxia-induced upregulation of VEGF mRNA in cervical cancer cell lines. National Library of Canada, 1998.

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2

1947-, Haddad Gabriel G., and Lister George 1947-, eds. Tissue oxygen deprivation: From molecular to integrated function. M. Dekker, 1996.

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3

Sukhamay, Lahiri, Cherniack Neil S, Fitzgerald Robert S. 1931-, American Physiological Society (1887- ), and Federation of American Societies for Experimental Biology., eds. Response and adaptation to hypoxia: Organ to organelle. Published for the American Physiological Society by Oxford University Press, 1991.

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4

Wobma, Holly Michelle. Interferon-gamma/Hypoxia Primed Mesenchymal Stem Cells for an Improved Immunosuppressive Cell Therapy. [publisher not identified], 2018.

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5

Low, Eddy Wai-Mang. Reactions toward the synthesis of minor-groove binding hypoxic cell sensitizers. National Library of Canada = Bibliothèque nationale du Canada, 1993.

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6

Jamie, Goode, Chadwick Derek, Novartis Foundation, and Symposium on the Tumour Microenvironment: Causes and Consequences of Hypoxia and Acidity (2000 : London, England), eds. The tumour microenvironment: Causes and consequences of hypoxia and acidity. Wiley, 2001.

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7

Cheng, Phillip Ming-Da. Relationship between modulation of Glomus Cell K+ current and hypoxia transduction in the rat carotid body. s.n.], 1997.

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8

Jean-Marc, Pequignot, ed. Chemoreception: From cellular signaling to functional plasticity. Kluwer Academic/Plenum Publishers, 2003.

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9

Koumenis, Constantinos, Amato Giaccia, and Ester Hammond. Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging, and Therapeutic Targets. Springer, 2013.

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10

Koumenis, Constantinos, Amato Giaccia, and Ester Hammond. Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging, and Therapeutic Targets. Springer, 2016.

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11

Koumenis, Constantinos, Amato Giaccia, and Ester Hammond. Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging, and Therapeutic Targets. Springer London, Limited, 2013.

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12

(Editor), Chandran K. Sen, and Gregg L. Semenza (Editor), eds. Oxygen Sensing, Volume 381 (Methods in Enzymology). Academic Press, 2004.

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13

Semenza, Gregg L., and Chandan K. Sen. Oxygen Sensing. Elsevier Science & Technology Books, 2004.

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14

Pastorekova, Silvia, and Juraj Kopacek. Tumour Hypoxia: Molecular Mechanisms and Clinical Implications. Lang GmbH, Internationaler Verlag der Wissenschaften, Peter, 2012.

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15

Cowan, David Stuart Mason. DNA targeted hypoxic cell radiosensitizers and cytotoxins. 1995.

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16

Melillo, Giovanni. Hypoxia and Cancer: Biological Implications and Therapeutic Opportunities. Springer-Verlag New York Inc., 2013.

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17

Melillo, Giovanni. Hypoxia and Cancer: Biological Implications and Therapeutic Opportunities. Springer London, Limited, 2013.

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18

Melillo, Giovanni. Hypoxia and Cancer: Biological Implications and Therapeutic Opportunities. Humana, 2016.

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19

Fitzgerald, Robert S., Neil S. Cherniak, and Sukhamay Lahiri. Response and Adaptation to Hypoxia: Organ to Organelle. Springer, 2013.

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20

Mechanisms by which hypoxia augments Leydig cell viability and differentiated cell function in vitro. Virginia Polytechnic Institute and State University, 1993.

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21

Soleymanlou, Nima. Human trophoblast cell death in pathological and physiological models of hypoxia. 2006.

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22

Matejovic, Jan Francis. Structure-activity relationships of DNA-targeted hypoxic cell radiosensitizers and cytotoxins. 1995.

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23

(Editor), Sukhamay Lahiri, Neil S. Cherniak (Editor), and Robert S. Fitzgerald (Editor), eds. Response and Adaptation to Hypoxia: Organ to Organelle (Clinical Physiology Series). An American Physiological Society Book, 1991.

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24

Fish, Jason Edward. Chromatin-based mechanisms control the cell-specific and hypoxia-regulated expression of endothelial nitric oxide synthase. 2006.

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25

Cancer: Between glycolysis and physical constraint. Springer, 2004.

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26

The Tumour Microenvironment - No. 240: Causes and Consequences of Hypoxia and Acidity (Novartis Foundation Symposia). Wiley, 2001.

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27

(Editor), Jean-Marc Pequignot, Constancio Gonzalez (Editor), Colin A. Nurse (Editor), Nanduri R. Prabhakar (Editor), and Yvette Dalmaz (Editor), eds. Chemoreception: From Cellular Signalling to Functional Plasticity (Advances in Experimental Medicine and Biology). Springer, 2003.

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28

(Editor), Yoshiaki Hayashida, Constancio Gonzalez (Editor), and Hisatake Kondo (Editor), eds. The Arterial Chemoreceptors (Advances in Experimental Medicine and Biology). Springer, 2006.

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29

The Arterial Chemoreceptors. Springer, 2006.

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30

Said, Harun M., Adrian Staab, and Carsten Hagemann. Brain-Cancer Associated Tumor Marker Genes Expression Pattern in Humans. Nova Science Publishers, Incorporated, 2011.

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31

Macdougall, Iain C. Erythropoiesis-stimulating agents in chronic kidney disease. Edited by David J. Goldsmith. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0124.

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The advent of recombinant human erythropoietin (epoetin) in the late 1980s transformed the management of renal anaemia, liberating many dialysis patients from lifelong regular blood transfusions, in turn causing severe iron overload and human leucocyte antigen sensitization. Epoetin can be administered either intravenously or subcutaneously, but the half-life of the drug is fairly short at around 6–8 hours, necessitating frequent injections. To circumvent this problem, two manipulations to the erythropoietin molecule were engineered. The first of these was to attach an extra two carbohydrate c
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