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Dissertations / Theses on the topic 'Cell attachment'

Author: Grafiati

Published: 4 June 2021

Last updated: 22 February 2023

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1

Barrett, Cindy L., James Russell Hayman, and Cheryl Moore. "Microsporidial Attachment and Host Cell Signaling." Digital Commons @ East Tennessee State University, 2021. https://dc.etsu.edu/asrf/2021/presentations/4.

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Microsporidia exploit several targets for binding to host cells. Attachment is known to be an important first step before infection, and by blocking attachment, host cell infection decreases. This project seeks to determine if microsporidia use an ADAM (A Disintegrin And Metalloprotease) like protein to bind to host integrins. To test this, spore adherence assays employed a small, generated peptide that selected the integrin binding domain of the ADAM like protein. Afterwards, spore attachment to cell culture was quantified to determine if the peptide blocked spore attachment to cell monolayer

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2

Ilvesaro, J. (Joanna). "Attachment, polarity and communication characteristics of bone cells." Doctoral thesis, University of Oulu, 2001. http://urn.fi/urn:isbn:9514259351.

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Abstract Bone resorbing osteoclasts require tight attachment of their plasma membrane to the bone surface in order to retain the specific microenvironment and thus to be able to dissolve the bone matrix underneath. Cadherins are transmembrane glycoproteins usually mediating homophilic calcium-dependent cell-cell adhesion. In the present work we have studied the effects of the cadherin CAR sequence HAV-containing hexapeptide AHAVSE on osteoclasts. The primary attachment of osteoclasts to bone surface is not affected by the peptide, suggesting that it is not mediated by cadherins. Treatme

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Sinnappan, Snega Marina Graduate School of Biomedical Engineering Faculty of Engineering UNSW. "Cell attachment to peplide modified glass surfaces." Awarded by:University of New South Wales. Graduate School of Biomedical Engineering, 2007. http://handle.unsw.edu.au/1959.4/29559.

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Cell attachment is vital for the integration of biomaterials in the body. Surface modification using cell adhesive peptides, such as Arginine-Glycine-Aspartic (RGD), has showed promise for enhancing cell adhesion. Cell adhesion on glass and polyethylene glycol (PEGylated) surfaces modified with active RGD and Proline- Histidine-Serine-Arginine-Asparagine (PHSRN) peptides as well as inactive RDG and HRPSN control peptides was investigated in serum free conditions using three cell lines; NIH3T3 fibroblasts, MC3T3 pre-osteoblasts and C2C12 pre-myoblasts. Peptide attachment to glass surfaces was c

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4

Lim, Rosanna Marie. "Attachment of polyelectrolyte multilayers to cells and the implications on cell behavior." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104211.

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Thesis: Ph. D. in Chemical Engineering Practice, Massachusetts Institute of Technology, Department of Chemical Engineering, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>The development of targeted drug delivery systems is of fundamental importance for the transport of highly toxic drugs to diseased cells. One way of achieving this is using biohybrid materials, which integrates synthetic components with cells in order to confer unique properties to existing biological systems. An example of this is the cell backpack, which consists of a circular, pol

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5

Kowaleski, Mark C. "Increasing Cell Attachment and Adhesion on Fibrin Micorthread Sutures for Cell Delivery." Digital WPI, 2012. https://digitalcommons.wpi.edu/etd-theses/1097.

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"The effectiveness of exogenous cellular therapies has been limited by the ability to efficiently and locally deliver cells to a region of interest. We have developed biological sutures, formed from fibrin microthreads, to overcome these delivery issues and demonstrated increased cell engraftment compared to the current gold standard. However, the cell seeding efficiency onto the sutures is low and during implantation cells are subjected to shear forces as the sutures are pulled through the tissue. As a result, cells go unused after seeding and an uneven distribution of cells from the entry po

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6

Reyes, Eduardo Alberto. "Flow chamber for studying cell attachment to opaque substrates." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0008971.

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7

Leijon, Jonas, Fredrik Carlsson, Johan Brännström, et al. "Attachment of macromolecular heparin conjugate to gelatin scaffolds improves endothelial cell infiltration." Uppsala universitet, Klinisk immunologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-195102.

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Long-term survival of implanted cells requires oxygen and nutrients, the need for which is met by vasculari- zation of the implant. The use of scaffolds with surface-attached heparin as anchoring points for angiogenic growth factors has been reported to improve this process. We examined the potential role of surface modification of gelatin scaffolds in promoting endothelial cell infiltration by using a unique macromolecular conjugate of heparin as a coating. Compared to other heparin coatings, this surface modification provides flexible heparin chains, representing a new concept in heparin con

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8

Redmann, Anna-Lena. "Kinetics of cell attachment and spreading on hard and soft substrates." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/290385.

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A very important aspect for the functioning of an organism is that cells adapt their behaviour to external stimuli. They continuously interact with their environment, and biochemical and physical cues can activate cellular signalling, which leads to changes in cell behaviour such as proliferation and shape. Understanding cells' interactions with their environment is also important for understanding diseases. For example mechanosensing, which is the sensing of the cell's mechanical environment, has been associated with cancer development. In order for a cell to be able to sense its mechanical e

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9

Moore, Edward Andrew. "Cell attachment and spreading on physical barriers used in periodontal guided tissue regeneration /." Oklahoma City : [s.n.], 2002. http://library.ouhsc.edu/epub/theses/Moore-William-A.pdf.

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10

Elseed, Mohammed. "Investigation of periodontal stem cell attachment to dentin and dental pulp stem cell migration." Thesis, NSUWorks, 2007. https://nsuworks.nova.edu/hpd_cdm_stuetd/12.

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11

Roca-Cusachs, Soulere Pere. "Role of substrate attachment in cell mechanics: Implications in neutrophils and microvascular endothelial cells." Doctoral thesis, Universitat de Barcelona, 2007. http://hdl.handle.net/10803/1134.

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EN CATALÀ DE LA TESI DOCTORAL<br/><br/>"Importància de l'adhesió al substrat en la mecànica cel·lular: Implicacions en neutròfils i cèl·lules endotelials microvasculars".<br/><br/>En organismes multicel·lulars complexos com els humans, el comportament de cèl·lules individuals ve dictat en gran mesura per les interaccions amb la matriu extracel·lular (ECM). La ECM és una xarxa de proteïnes filamentoses (com ara col·lagen, fibronectina o laminina) que proporciona un substrat físic per l'adhesió cel·lular. L'adhesió a la ECM està mitjançada bàsicament per les integrines, que són un tipus de prote

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12

Huo, Hongguang. "Tailored cell attachment and cytotoxicity in PEG-based polysaccharide-derivatized hydrogels." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 117 p, 2007. http://proquest.umi.com/pqdlink?did=1253510481&Fmt=7&clientId=79356&RQT=309&VName=PQD.

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13

Gill, Amritpal Singh. "Development of a Novel Single-Cell Attachment and Spreading Platform Utilizing Fused-Fiber Nanonets." Thesis, Virginia Tech, 2015. http://hdl.handle.net/10919/73504.

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Initial attachment to the extracellular matrix (ECM) and consequent spreading is a necessary process in the cell cycle of which little is known. Cell spreading has been well-recognized in 2D systems, however, the native fibrous ECM presents cells with 3D biophysical cues. Thus, using suspended fibers as model systems, we present the development of a novel platform (Cell-STEPs) capable of capturing cell attachment dynamics and forces from the moment a cell in suspension contacts the fiber. Cell-STEPs comprises of a custom glass-bottom petri dish with a lid to deliver a constant supply of CO2

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14

Kern, David M. (David Matthew). "Regulation of microtubule attachment at the kinetochore and cell cortex." Thesis, Massachusetts Institute of Technology, 2015. http://hdl.handle.net/1721.1/103239.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, February 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references.<br>During mitosis, the cell divides in two, evenly distributing the genetic material and splitting the rest of cellular contents between the resulting daughter cells. This process is essential, rapid, and complex, requiring precise timing and the collaboration of many proteins. Mistakes made during mitosis can have immediate and catastrophic effects, resulting in cell death. In an organismal context, small mistakes in the

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15

Martins, Cláudia Isabel Rodrigues. "Platelet lysates loaded laminarin micropartcicles for cell attachment and expansion." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22763.

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Mestrado em Biotecnologia Industrial e Ambiental<br>A engenharia de tecidos tem estudado a combinação de vários materiais com células com o intuito de solucionar alguns problemas que as atuais terapias não conseguem dar resposta. Umas das respostas passa pelo desenvolvimento de pequenas estruturas, microgéis, que mimetizam a matriz extracelular e podem interagir de várias formas para criar uma estrutura tridimensional complexa. Este trabalho resume as principais técnicas de microfabricação que têm sido usadas no desenvolvimento de microgéis assim como as principais aplicações destas na

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16

Henry, Matthew S. "Characterization of a lambdoid phage gene encoding a host cell attachment spike." Bowling Green, Ohio : Bowling Green State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=bgsu1214189208.

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17

Krieg, Michael, Alba Diz-Muñoz, Martin Bergert, et al. "Control of Directed Cell Migration In Vivo by Membrane-to-Cortex Attachment." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-180853.

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Cell shape and motility are primarily controlled by cellular mechanics. The attachment of the plasma membrane to the underlying actomyosin cortex has been proposed to be important for cellular processes involving membrane deformation. However, little is known about the actual function of membrane-to-cortex attachment (MCA) in cell protrusion formation and migration, in particular in the context of the developing embryo. Here, we use a multidisciplinary approach to study MCA in zebrafish mesoderm and endoderm (mesendoderm) germ layer progenitor cells, which migrate using a combination of differ

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18

Fischer, Joshua Richard. "Mechanisms of Host Cell Attachment by the Lyme Disease Spirochete: A Dissertation." eScholarship@UMMS, 2005. http://escholarship.umassmed.edu/gsbs_diss/194.

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Host cell binding is an essential step in colonization by many bacterial pathogens, and the Lyme disease agent, Borrelia burgdorferi, which colonizes multiple tissues, is capable of attachment to diverse cell types. Glycosaminoglycans (GAGs) are ubiquitously expressed on mammalian cells and are recognized by multiple B. burgdorferi surface proteins. We previously showed that B. burgdorferi strains differ in the particular spectrum of GAGs that they recognize, leading to differences in the cultured mammalian cell types that they efficiently bind. The molecular basis of these binding specificiti

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Benoit, Vivian M. "Host Cell Attachment by Lyme Disease and Relapsing Fever Spirochetes: A Dissertation." eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/512.

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Host cell attachment by pathogenic bacteria can play very different roles in the course of infection. The pathogenic spirochetes Borrelia hermsii and Borrelia burgdorferi sensu lato which cause relapsing fever and Lyme disease, respectively, are transmitted by the bite of infected ticks. After transmission, these spirochetes can cause systemic infection. Relapsing fever spirochetes remain largely in the bloodstream causing febrile episodes, while Lyme disease will often colonize a variety of tissues, such as the heart, joint and nervous system, resulting in a chronic multisystemic disorder. Bo

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20

Ganeshkumar, Nadarajah. "Streptococcus sanguis adhesins mediating attachment to saliva-coated hydroxyapatite beads." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/28785.

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Streptococcus sanguis 12 adhesins mediating attachment to saliva-coated hydroxyapatite beads (S-HA) were isolated and characterized. Cell surface fibrils were released from this organism by a method of freeze-thawing followed by brief homogenization. Fibrils in the homogenate were precipitated by ultracentrifugation or ammonium sulphate precipitation. This precipitate was shown to contain fibrils by electron microscopy. Sodium dodecyl sulphate (SDS)-polyacrylamide gel electrophoresis (PAGE) analysis of fibrils showed a single band which stained with Coomassie blue and periodate-Schiff. The mol

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21

D'Antoni, Michelle. "The effect of decorin and biglycan on human airway smooth muscle cell proliferation, apoptosis and attachment." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103624.

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Changes in extracellular matrix (ECM) deposition along with increases in airway smooth muscle (ASM) mass are characteristic features of airway remodeling which contribute to asthma pathophysiology. Modifications in ECM include increased collagen deposition and altered proteoglycans (PGs) levels. While biglycan, a small leucine-rich PG (SLRP), deposition is generally increased, changes in decorin, another SLRP, are more variable. The interaction between the cell and the surrounding ECM triggers numerous cellular responses, which modulate functions such as survival, proliferation and differen

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22

Munoz, Robledo Lyn G. "Attachment and Growth of Aortic Adventitial Fibroblasts on Polyisobutylene-based Thermoplastic Elastomers." University of Akron / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=akron1208204988.

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23

Sitbon, Yves Alain Dietrich. "Epithelial cells attachment on five different dental implant abutment surface candidates." Thesis, University of Iowa, 2009. https://ir.uiowa.edu/etd/266.

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Objectives: the hypothesis of this study was that different abutment substrates would not affect epithelial cell attachment and differentiation. Methods: 15 discs for each of 5 different materials (4 types of titanium and 1 type of zirconium) were flooded with a media containing human adenoid epithelial cells (hTERT). Cells were allowed to attach on the discs for 2 hours. The media was then collected, and remaining suspended cells counted, to determine number of attached cells. Surfaces were then flooded with fresh media, collected 24 hours later. Levels of 6 different pro-inflammatory cytokin

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Cereser, Biancastella. "The role of cell attachment in the regulation of telomerase during keratinocyte differentiation." Thesis, Queen Mary, University of London, 2010. http://qmro.qmul.ac.uk/xmlui/handle/123456789/421.

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The catalytic subunit of telomerase TERT has non-canonical functions, which are independent of telomere elongation and sometimes telomerase activity. In skin keratinocytes, both TERT expression and anoikis are regulated by extracellular matrix molecules and their integrin receptors, but the effect of TERT deregulation on anoikis has not been previously investigated. HaCaT cells expressing wild-type TERT, TERT-HA (non-canonical function only) DnTERT (catalytically inactive TERT) and the empty vector (PURO) were created by retroviral transduction. HaCaT anoikis was monitored after disengagement

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Muniz, Maisonet Maritza. "Topographical Enhancement of Cell Adhesion on Poorly Adhesive Materials." Scholar Commons, 2015. https://scholarcommons.usf.edu/etd/5748.

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The overall thrust of this dissertation is to gain a fundamental understanding of the synergistic effects between surface topography and chemical functionality of poorly adhesive materials on enhancing the adhesion of mouse embryonic fibroblasts. Cellular response to surface topography and chemical functionality have been extensively studied on their own providing valuable information that helps in the design of new and improved biomaterials for tissue engineering applications. However, there is a lack of understanding of the synergistic effect of microscale and nanoscale topography with chemi

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Lydic, Melissa. "The Characteristics of Rabbit and Rat Mesenchymal Stromal Cell Growth and Attachment to Mesh Used in Hernia Repair." Youngstown State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1278102053.

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27

Ahwaide, Hoda S. "Effects of IGF-1, IGFBP-5 and TGFB1 on cell proliferation, attachment and migration in mammary epithelial and mesenchymal cells." Thesis, University of Strathclyde, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502317.

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Insulin-like Growth Factors (IGFs) are a determining factor in breast cancer development since high circulating concentrations of IGF-I are associated, in previous epidemiological studies, with an increased risk of breast cancer. The actions of IGF-I, which plays an important survival role for several cell types and protect cells from apoptosis, is modulated by a family of IG; proteins (IGFBPs) IGFBP-5 has been proposed to induce cell death of epithelial and mesenchymal cells, but, failed to enhance mammary epithelial cell attachment. This research initially examined the effects of growth fact

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Sen, Atanu. "Quantification of cell attachment on different materials as candidate electrodes for measurement of quantal exocytosis." Diss., Columbia, Mo. : University of Missouri-Columbia, 2008. http://hdl.handle.net/10355/5722.

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Thesis (M.S.)--University of Missouri-Columbia, 2008.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on August 14, 2009) Includes bibliographical references.

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Clémence, Jean-François. "Engineering of biocompatible material systems by light : spatial control of neuronal cell attachment and differentiation /." [S.l.] : [s.n.], 1995. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.

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30

Sparks, David J. "Simulating the role of molecular binding to mineral surfaces : from biomineral growth to cell attachment." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/12004/.

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The interactions between organic molecules and minerals is fundamental to the under- standing of processes such as biomineralisation, the attachment of bacteria to surfaces and the design of synthetic materials within biomimetics. This thesis shows how molec- ular dynamics simulations can be employed to study the organic - inorganic interactions and give new insights into the molecular binding at mineral surfaces that play a role in these processes. The incorporation of amino acids within calcium carbonate crystals was simulated and show a high energy associated with the incorporation of these

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31

Nelson, Kjell Erik. "Investigating cell adhesion to controlled surface chemistry via self-assembly of binary composition alkylthiol monolayers, streptavidin immobilization, and cell receptor ligand attachment /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/8051.

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32

Kandimalla, Yugandhar. "Study of Chitosan Microparticles with Bone Marrow Mesenchymal Stem Cells for Bone Tissue Regeneration." University of Toledo Health Science Campus / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=mco1250778129.

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33

Sethi, Kamaljit Kaur. "Control of fibroblast-mediated collagen contraction : importance and mechanism of cell attachment in the contraction process." Thesis, University College London (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313283.

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Markkula, Tommi. "Surface characterisation of gas plasma modified PET and PTFE : effect of surface chemistry on cell attachment." Thesis, University of Liverpool, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275047.

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Davison, Elizabeth Anne. "Mechanisms of adenovirus type 5 interaction with host cell surface receptors for viral attachment and internalisation." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395828.

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36

Boyer, Renee R. "Mechanisms Associated with Attachment of Escherichia coli O157:H7 to Lettuce Surfaces." Diss., Virginia Tech, 2006. http://hdl.handle.net/10919/27003.

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Fresh produce is increasingly associated with foodborne outbreaks. In order to develop effective intervention and measures to reduce microbial risks, it is essential to attain a better understand the mechanisms of attachment of foodborne pathogens to fruits and vegetables. Using lettuce as a model, the attachment of Escherichia coli O157:H7 to produce surfaces was studied. Strains expressing various extracellular proteins (curli, O157-antigen, and intimin) known to influence attachment of E. coli to intestinal cells were evaluated for their physicochemical properties and ability to adhere to

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Jones-Dozier, Shelby L. "Proteomic Analysis of the Response of Pseudomonas Aeruginosa PAO1 to the Cell to Cell Signaling Molecule Trans, Trans-farnesol of Candida Albicans." Digital Archive @ GSU, 2008. http://digitalarchive.gsu.edu/biology_diss/84.

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Nosocomial infections associated with implanted medical- devices are on the rise due to a growing immunocompromised patient population. The organisms of interest in this study are Pseudomonas aeruginosa and Candida albicans. These organisms are opportunistic pathogens and are frequently implicated as the cause of infection and colonization of medical devices. P. aeruginosa is a motile gram-negative bacterium that is able to suppress the growth of C. albicans. Quourm sensing mimicry and biofilm formation on the hyphal surface of C. albicans by P. aeruginosa aids in suppression. C. albicans is a

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Zhao, Mingrui, and Manish Keswani. "Fabrication of Radially Symmetric Graded Porous Silicon using a Novel Cell Design." NATURE PUBLISHING GROUP, 2016. http://hdl.handle.net/10150/614761.

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A contactless method using a novel design of the experimental cell for formation of porous silicon with morphological gradient is reported. Fabricated porous silicon layers show a large distribution in porosity, pore size and depth along the radius of the samples. Symmetrical arrangements of morphology gradient were successfully formulated radially on porous films and the formation was attributed to decreasing current density radially inward on the silicon surface exposed to Triton (R) X-100 containing HF based etchant solution. Increasing the surfactant concentration increases the pore depth

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Sharma, Lohit sharma. "Initial Attachment of Pseudomonas Aeruginosa on Modified Polycardonal Coatings." University of Toledo / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1470427782.

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Knockleby, James. "A role for the «Saccharomyces cerevisiae» kinetochore protein Ame1 in cell cycle control and MT-kinetochore attachment." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=22031.

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High fidelity chromosome segregation in all cells requires the formation of bi-oriented attachments between spindle microtubules (MT) and chromosomes. The kinetochore provides a bridge between the MTs and chromosomes. Ame1 is an essential but undercharacterized component of the central kinetochore COMA sub-complex (Ctf19, Okp1, Mcm21, Ame1). In order to characterize Ame1, I used two conditional alleles of the COMA, ame1-4 and okp1-5. I examined the role of Ame1 in the context of the kinetochore and in the maintenance of the spindle assembly checkpoint (SAC) and the formation and repair of kine

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Jia, Hongxia. "Attachment ability and melanoma inhibitory activity mRNA expression level changes in murine B16-F10 melanoma cells post nanosecond electric pulses." Thesis, Old Dominion University, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=3576652.

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<p>The effects of high-voltage nanosecond electric pulses (nsEPs) on metastatic melanoma are still unclear. Hence, we applied one, two, three, and four 300 ns 40 kV/cm pulses to murine B16-F10 melanoma cells. Cell attachment ability was determined by comparing the number of floating cells and the percentage of attached cells. Melanoma inhibitory activity (MIA) is a secretory protein that is highly correlated with the malignancy and metastasis of malignant melanomas. We used MIA as our target to evaluate the effect of nsEPs on metastasis. Pulsed (experimental) and unpulsed (control) cells were

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Vitiello, E. "DLC-2, a CDC42 gap involved in attachment of microtubules at the cell cortex and at the kinetochores." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1419276/.

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Maintenance of epithelial tissue integrity requires correct organization of the polarity plane. This is promoted by assembly of cell-cell junctions, defining distinctive apical and basolateral domains. The establishment of polarity is a key point in tissue organization since it controls the plane in which cells divide. When a cell replicates, it duplicates DNA and aligns them before partitioning them evenly between the two daughter cells. Although results from different laboratories indicate a role of cell-cell junctions in the orientation of the mitotic spindle, it is poorly understood if the

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Kontoveros, Dimitria. "Schwann Cell Proliferation and Migration in Response to Surface Bound Peptides for Nerve Regeneration." University of Akron / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=akron1431035725.

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Pitt, Darren William. "Design of polymer systems and surface-active agents for the improvement of cell attachment for treatment of ocular diseases." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/380880/.

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The degradation of eyesight is a frightening experience for individuals and unfortunately gradual loss of vision with old age is commonplace. One of the most common forms of eye disease which effects vision is Age-Related Macular Degeneration (AMD). AMD is the leading cause of blindness in the developed world and there is currently no cure for the disease. One treatment option available for the neovascular form of AMD is the injection of Bevacizumab [an anti-vascular endothelial growth factor (VEGF) drug] into the eye on a monthly basis. Investigation into the biodegradable polymers poly(L-lac

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Tseng, Jerming. "The binding of human C-reactive protein (CRP) to plasma fibronectin and its effect on cell attachment-promoting activity /." The Ohio State University, 1988. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487588249821906.

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Latorre-Barragan, Fernanda. "From force generation to host cell attachment : new function of the acto-MyoA motor complex in Toxoplasma gondii tachyzoites." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/30579/.

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The Apicomplexan parasite Toxoplasma gondii is considered an extremely successful pathogen for its capacity to invade virtually any nucleated cell. Host cell invasion is an active process thought to be driven by the same acto-myosin machinery that drives gliding motility. The current model suggests that at the core of the complex is MyoA, a small unconventional class XIVa myosin, which, together with its molecular partner myosin light chain 1 (MLC1), produces mechanical force on short actin (ACT1) filaments to power gliding and invasion. However, efficient conditional removal of the key compon

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Jouret, Chantal. "Effects of matrix and phenotype on human dermal fibroblast attachment under laminar shear stress : implications for the development of tissue-engineered heart valves." Thesis, Georgia Institute of Technology, 1997. http://hdl.handle.net/1853/11251.

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48

Wilson, Cameron. "Mediation of Osteoblast Responses to Titanium Roughness by Adsorbed Proteins." Queensland University of Technology, 2005. http://eprints.qut.edu.au/16096/.

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Abstract:

Stable fixation of implants such as artificial teeth depends on the direct apposition of bone to the implanted material. While endosseous implants were traditionally allowed to "osseointegrate" over several months without carrying load, clinical and experimental data show that prostheses with roughened surfaces allow successful integration when subject to earlier loading and more challenging implant sites. However, to design implant surfaces for an optimal biological response requires an understanding of the mechanism by which roughened surfaces promote osseointegration. Research into this me

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49

Wilson, Cameron John. "Mediation of Osteoblast Responses to Titanium Roughness by Adsorbed Proteins." Thesis, Queensland University of Technology, 2005. https://eprints.qut.edu.au/16096/1/Cameron_Wilson_Thesis.pdf.

Full text

Abstract:

Stable fixation of implants such as artificial teeth depends on the direct apposition of bone to the implanted material. While endosseous implants were traditionally allowed to "osseointegrate" over several months without carrying load, clinical and experimental data show that prostheses with roughened surfaces allow successful integration when subject to earlier loading and more challenging implant sites. However, to design implant surfaces for an optimal biological response requires an understanding of the mechanism by which roughened surfaces promote osseointegration. Research into this me

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50

Hatchel, Jennifer M. "Structure and Function of the Electron-dense Core in Mycoplasma pneumoniae and its Relatives." Miami University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=miami1248183957.

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