Academic literature on the topic 'Cell fat plasticity'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Cell fat plasticity.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Cell fat plasticity"

1

Casteilla, Louis, Béatrice Cousin, and Mamen Carmona. "PPARs and Adipose Cell Plasticity." PPAR Research 2007 (2007): 1–7. http://dx.doi.org/10.1155/2007/68202.

Full text
Abstract:
Due to the importance of fat tissues in both energy balance and in the associated disorders arising when such balance is not maintained, adipocyte differentiation has been extensively investigated in order to control and inhibit the enlargement of white adipose tissue. The ability of a cell to undergo adipocyte differentiation is one particular feature of all mesenchymal cells. Up until now, the peroxysome proliferator-activated receptor (PPAR) subtypes appear to be the keys and essential players capable of inducing and controlling adipocyte differentiation. In addition, it is now accepted tha
APA, Harvard, Vancouver, ISO, and other styles
2

Olson, Lorin E., та Philippe Soriano. "PDGFRβ Signaling Regulates Mural Cell Plasticity and Inhibits Fat Development". Developmental Cell 20, № 6 (2011): 815–26. http://dx.doi.org/10.1016/j.devcel.2011.04.019.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Bielczyk-Maczynska, Ewa. "White Adipocyte Plasticity in Physiology and Disease." Cells 8, no. 12 (2019): 1507. http://dx.doi.org/10.3390/cells8121507.

Full text
Abstract:
Cellular plasticity is a transformation of a terminally differentiated cell into another cell type, which has been long known to occur in disease and regeneration. However, white adipocytes (fat cells) have only recently been observed to undergo different types of cellular plasticity. Adipocyte transdifferentiation into myofibroblasts and cancer-associated fibroblasts occurs in fibrosis and cancer, respectively. On the other hand, reversible adipocyte dedifferentiation into adipocyte progenitor cells (preadipocytes) has been demonstrated in mammary gland and in dermal adipose tissue. Here we d
APA, Harvard, Vancouver, ISO, and other styles
4

MOULIN, Karine, Nathalie TRUEL, Mireille ANDRÉ, et al. "Emergence during development of the white-adipocyte cell phenotype is independent of the brown-adipocyte cell phenotype." Biochemical Journal 356, no. 2 (2001): 659–64. http://dx.doi.org/10.1042/bj3560659.

Full text
Abstract:
In mammals, two types of adipose tissue are present, brown and white. They develop sequentially, as brown fat occurs during late gestation whereas white fat grows mainly after birth. However, both tissues have been shown to have great plasticity. Thus an apparent transformation of brown fat into white fat takes place during post-natal development. This observation raises questions about a possible conversion of brown into white adipocytes during development, although indirect data argue against this hypothesis. To investigate such questions in vivo, we generated two types of transgenic line. T
APA, Harvard, Vancouver, ISO, and other styles
5

Herzog, Erica L., Li Chai, and Diane S. Krause. "Plasticity of marrow-derived stem cells." Blood 102, no. 10 (2003): 3483–93. http://dx.doi.org/10.1182/blood-2003-05-1664.

Full text
Abstract:
AbstractBone marrow (BM) contains hematopoietic stem cells (HSCs), which differentiate into every type of mature blood cell; endothelial cell progenitors; and marrow stromal cells, also called mesenchymal stem cells (MSCs), which can differentiate into mature cells of multiple mesenchymal tissues including fat, bone, and cartilage. Recent findings indicate that adult BM also contains cells that can differentiate into additional mature, nonhematopoietic cells of multiple tissues including epithelial cells of the liver, kidney, lung, skin, gastrointestinal (GI) tract, and myocytes of heart and s
APA, Harvard, Vancouver, ISO, and other styles
6

Linehan, Victoria, Lisa Z. Fang, Matthew P. Parsons, and Michiru Hirasawa. "High-fat diet induces time-dependent synaptic plasticity of the lateral hypothalamus." Molecular Metabolism 36 (June 2020): 100977. http://dx.doi.org/10.1016/j.molmet.2020.100977.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

De Fano, Michelatonio, Desirèe Bartolini, Cristina Tortoioli, et al. "Adipose Tissue Plasticity in Response to Pathophysiological Cues: A Connecting Link between Obesity and Its Associated Comorbidities." International Journal of Molecular Sciences 23, no. 10 (2022): 5511. http://dx.doi.org/10.3390/ijms23105511.

Full text
Abstract:
Adipose tissue (AT) is a remarkably plastic and active organ with functional pleiotropism and high remodeling capacity. Although the expansion of fat mass, by definition, represents the hallmark of obesity, the dysregulation of the adipose organ emerges as the forefront of the link between adiposity and its associated metabolic and cardiovascular complications. The dysfunctional fat displays distinct biological signatures, which include enlarged fat cells, low-grade inflammation, impaired redox homeostasis, and cellular senescence. While these events are orchestrated in a cell-type, context-de
APA, Harvard, Vancouver, ISO, and other styles
8

Rabhi, Nabil, and Stephen R. Farmer. "Unraveling the complexity of thermogenic remodeling of white fat reveals potential antiobesity therapies." Genes & Development 35, no. 21-22 (2021): 1395–97. http://dx.doi.org/10.1101/gad.349053.121.

Full text
Abstract:
Adipose tissue is a complex organ consisting of a mixture of mature adipocytes and stromal vascular cells. It displays a remarkable ability to adapt to environmental and dietary cues by changing its morphology and metabolic capacity. This plasticity is demonstrated by the emergence of interspersed thermogenic beige adipocytes within white depots in response to catecholamines secretion. Coordinated cellular interaction between different cell types within the tissue and a fine-tuned transcriptional program synergistically take place to promote beige remodeling. However, both cell–cell interactio
APA, Harvard, Vancouver, ISO, and other styles
9

Petan, Toni, Eva Jarc, and Maida Jusović. "Lipid Droplets in Cancer: Guardians of Fat in a Stressful World." Molecules 23, no. 8 (2018): 1941. http://dx.doi.org/10.3390/molecules23081941.

Full text
Abstract:
Cancer cells possess remarkable abilities to adapt to adverse environmental conditions. Their survival during severe nutrient and oxidative stress depends on their capacity to acquire extracellular lipids and the plasticity of their mechanisms for intracellular lipid synthesis, mobilisation, and recycling. Lipid droplets, cytosolic fat storage organelles present in most cells from yeast to men, are emerging as major regulators of lipid metabolism, trafficking, and signalling in various cells and tissues exposed to stress. Their biogenesis is induced by nutrient and oxidative stress and they ac
APA, Harvard, Vancouver, ISO, and other styles
10

Baragetti, Andrea, and Giuseppe Danilo Norata. "The High Fat Diet Impacts the Plasticity between Fresh and Aged Neutrophils." Journal of Cellular Immunology 5, no. 5 (2023): 168–73. http://dx.doi.org/10.33696/immunology.5.182.

Full text
Abstract:
Metabolic alterations induced by unhealthy lifestyles, including obesity and insulin resistance are often associated with increased innate immune response and chronic inflammation. Cholesterol has been identified as a key metabolite driving the activation of the inflammasome and the “epigenetic memory” in long-term living hematopoietic stem cells. In addition to these mechanisms, the physiological aging of short-living neutrophils is a relevant modifier of their immune competency, as while they egress from medullary niches as “fresh”, fully competent, cells, they turn into “aged”, disarmed cel
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Cell fat plasticity"

1

Caldarelli, Paolo. "On the role of mechanical forces in embryonic self-organization." Electronic Thesis or Diss., Sorbonne université, 2021. http://www.theses.fr/2021SORUS189.

Full text
Abstract:
Les cellules se divisent, migrent, se réarrangent et acquièrent différents destins au cours du développement embryonnaire tout en s'organisant de manière à constituer un organisme de forme adéquate. Il est de plus en plus reconnu que la régulation de ces événements est contrôlée par des mécanismes d'auto-organisation. À la suite des travaux pionniers d'Alan Turing, qui a postulé, dans son modèle de réaction-diffusion, que l'interaction entre les molécules pouvait contrôler l'auto-organisation, des études ultérieures se sont concentrées sur l'identification des molécules de signalisation répond
APA, Harvard, Vancouver, ISO, and other styles
2

Eid, André. "Mechanisms of cell fate and chromatin plasticity during early mouse embryogenesis." Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAJ014/document.

Full text
Abstract:
La chromatine embryonnaire subit des changements nécessaires pour l’établissement d’un nouveau programme développemental. Ce travail a étudié l’organisation de l’hétérochromatine au cours du développement sous trois facettes. La première étant celle de d’hétérochromatine constitutive, à travers, l’établissement forcé de la marque H4K20me3 qui provoque un arrêt du développement préimplantatoire. Ce phénotype dépend spécifiquement de l’activité de la methyltransferase SUV4-20h2 et induit l’activation de la voie de signalisation ATR qui bloque la phase de réplication. En deuxième partie, l’hétéro
APA, Harvard, Vancouver, ISO, and other styles
3

André-Ratsimbazafy, Marie. "Phenotype plasticity and populations’ dynamics : social interactions among cancer cells." Thesis, Sorbonne Paris Cité, 2016. http://www.theses.fr/2016USPCB032/document.

Full text
Abstract:
On admet communément que les tumeurs proviennent de cellules échappant aux contrôles homéostatiques qui sous-tendent les structures histologiques saines et que le phénotype d’une cellule n’est pas le résultat de processus génétiques et biochimiques déterministes mais la conséquence stochastique de réseaux de régulation intra- et intercellulaires. Ce doctorat vise à étudier quantitativement l’homéostasie phénotypique de populations cellulaires et à présenter une approche à la question fondamentale, mais jusqu’alors jamais étudiée, concernant l’autonomie versus le contrôle collectif du devenir d
APA, Harvard, Vancouver, ISO, and other styles
4

Son, Yesde. "Exploring the Plasticity of Cellular Fate Using Defined-Factor Reprogramming." Thesis, Harvard University, 2012. http://dissertations.umi.com/gsas.harvard:10309.

Full text
Abstract:
Cellular fate, once established, is usually stable for the lifetime of the cell. However, the mechanisms that restrict the developmental potential of differentiated cells are in principle reversible, as demonstrated by the success of animal cloning from a somatic genome through somatic cell nuclear transfer (SCNT). An increased understanding of the molecular determinants of cell fate has also enabled the reprogramming of cell fate using defined transcription factors; recently, these efforts have culminated in the discovery of four genes that convert somatic cells into induced pluripotent stem
APA, Harvard, Vancouver, ISO, and other styles
5

Saiz, Nestor. "Regulation of cell fate and cell behaviour during primitive endoderm formation in the early mouse embryo." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/regulation-of-cell-fate-and-cell-behaviour-during-primitive-endoderm-formation-in-the-early-mouse-embryo(d40bb786-85ed-4efd-af64-aab331df98e8).html.

Full text
Abstract:
The preimplantation stages of mammalian development are dedicated to the differentiation of two extraembryonic epithelia, the trophectoderm (TE) and the primitive endoderm (PrE), and their segregation from the pluripotent embryonic lineage, the epiblast. The TE and PrE are responsible for implantation into the uterus and for producing the tissues that will support and pattern the epiblast as it develops into the foetus. PrE and epiblast are formed in a two step process that involves random cell fate specification, mediated by fibroblast growth factor (FGF) signalling, and cell sorting through
APA, Harvard, Vancouver, ISO, and other styles
6

Flici, Hakima. "Différenciation et plasticité des cellules souches neurales." Phd thesis, Université de Strasbourg, 2012. http://tel.archives-ouvertes.fr/tel-01070644.

Full text
Abstract:
L'étude de la plasticité cellulaire est un puissant outil pour comprendre le choix du destin cellulaire pendant la différenciation et dans les processus cancéreux lors de la transformation d'une cellule normale en une cellule maligne. Chez la drosophile, le facteur de transcription Gcm contrôle la détermination du destin glial. Dans des mutants gcm, les cellules qui se développent normalement en glie entrent dans la voie de différenciation neuronale alors que l'expression ectopique de gcm dans des progéniteurs neuronaux induit de la glie. Ces données font de Gcm un outil important pour compren
APA, Harvard, Vancouver, ISO, and other styles
7

Jarjour, Meryem. "Plasticité des réseaux de cellules folliculaires dentritiques : Développement & remodelage." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM4014.

Full text
Abstract:
Les Cellules Folliculaires Dendritiques (FDC) régulent l'homéostasie des lymphocytes B et sont indispensables à la mise en place des réponses immunes humorales. Les FDC s'organisent, au sein des organes lymphoïdes secondaires, en réseaux tridimensionnels denses, nécessaires à leur fonctionnement. Les études s'intéressant aux FDCs, empruntent classiquement des approches in vitro ou ex vivo, peu adaptées à la nature de ce type cellulaire. Au cours de mon travail de thèse, nous avons utilisé plusieurs systèmes de 'multicolor fate mapping' dans le but de déchiffrer in situ les mécanismes à l'origi
APA, Harvard, Vancouver, ISO, and other styles
8

Polgárová, Kamila. "Diferenciační plasticita hematopoetických buněk." Doctoral thesis, 2019. http://www.nusl.cz/ntk/nusl-404420.

Full text
Abstract:
Hematopoiesis has been for many years seen as a straightforward process based on sequential restriction of cell fate potential leading to production of mature blood cells. In the last decade, however, several works documented an unexpected plasticity of hematopoietic cells with expanded potential of myeloid development from lymphoid progenitors and vice versa. Under physiologic conditions hematopoiesis is tightly controlled and the definite cell fate is denominated by multiple factors that all lead to changes in regulatory networks that include transcription factors, epigenetic changes and pos
APA, Harvard, Vancouver, ISO, and other styles
9

Patel, Tulsi. "Cell fate restriction in Caenorhabditis elegans is orchestrated by precise chromatin organization and transcription factor activity." Thesis, 2016. https://doi.org/10.7916/D8H1321F.

Full text
Abstract:
The plasticity of cells in a multicellular organism is progressively lost during differentiation. This loss is reflected in studies involving the ectopic misexpression of fate-specifying or terminal selector transcription factors (TFs). These TFs can efficiently activate target genes in undifferentiated cells, but lose this ability as cells differentiate. While this phenomenon of cell fate restriction is widely observed, the mechanisms orchestrating it are poorly understood. In this thesis, I have used the ubiquitous overexpression of Zn-finger-TF CHE-1 as a tool to understand the mechanisms t
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Cell fat plasticity"

1

Dani, Christian. "Fat Cell Progenitors: Origins and Plasticity." In Research and Perspectives in Endocrine Interactions. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-13517-0_7.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Jiang, Jinxia, Min Feng, Annemarie Jacob, Lin Z. Li, and He N. Xu. "Optical Redox Imaging Differentiates Triple-Negative Breast Cancer Subtypes." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-48238-1_40.

Full text
Abstract:
AbstractTriple-negative breast cancer (TNBC) is a highly diverse group of cancers with limited treatment options, responsible for about 15% of all breast cancers. TNBC cells differ from each other in many ways such as gene expression, metabolic activity, tumorigenicity, and invasiveness. Recently, many research and clinical efforts have focused on metabolically targeted therapy for TNBC. Metabolic characterization of TNBC cell lines can facilitate the assessment of therapeutic effects and assist in metabolic drug development. Herein, we used optical redox imaging (ORI) techniques to characteri
APA, Harvard, Vancouver, ISO, and other styles
3

Cinti, Saverio. "The Nutritional System." In Perspectives in Nursing Management and Care for Older Adults. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63892-4_17.

Full text
Abstract:
AbstractThe white and brown adipose tissues are organized to form a true organ. They have a different anatomy and perform different functions, but they collaborate thanks to their ability to convert mutually and reversibly following physiological stimuli. This implies a new fundamental property for mature cells, which would be able to reversibly reprogram their genome under physiological conditions. The subcutaneous mammary gland provides another example of their plasticity. Here fat cells are reversibly transformed into glands during pregnancy and breastfeeding. The obese adipose organ is inf
APA, Harvard, Vancouver, ISO, and other styles
4

Kokai, Lauren, and J. Peter Rubin. "Plastic surgery, fat, and fat plasticity: How adipose tissue changed the landscape of stem cell therapeutics." In Scientific Principles of Adipose Stem Cells. Elsevier, 2022. http://dx.doi.org/10.1016/b978-0-12-819376-1.00009-3.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Wolf, Jason B., Edmund D. Brodie, and Michael J. Wade. "The Genotype-Environment Interaction and Evolution When the Environment Contains Genes." In Phenotypic Plasticity. Oxford University PressNew York, NY, 2004. http://dx.doi.org/10.1093/oso/9780195138962.003.0011.

Full text
Abstract:
Abstract The context in which genes are expressed is often a major determinant of the phenotype (including fitness) associated with a given genotype (Schlichting and Pigliucci 1998; Wolf et al. 2000; chapter I). Contexts that influence genetic effects span a hierarchy that begins within the cell and extends beyond the individual as far as the ecological community. Below the level of the individual, such context dependence is called epistasis, wherein the genetic background provided by other loci influences the effect that a given locus has on the phenotype. Epistasis may also arise when the cy
APA, Harvard, Vancouver, ISO, and other styles
6

Engleka, Kurt A., Deborah Lang, Christopher B. Brown, Nicole B. Antonucci,, and Jonathan A. Epstein. "Neural Crest Formation and Craniofacial Development." In Inborn Errors Of Development. Oxford University PressNew York, NY, 2008. http://dx.doi.org/10.1093/oso/9780195306910.003.0006.

Full text
Abstract:
Abstract Neural crest describes a transitory group of pluripotent epithelial cells that originates from the dorsalmost ridges of the embryonic neural tube. During early development, many of these cells collectively transform to a mesenchymal phenotype, assuming new morphological characteristics distinct from their epithelial neighbors, segregate from the neural tube and stream through speci7c routes into neighboring tissue environments in a wave of proliferation and migration. The resultant cells spread along migratory pathways that may end relatively far from the neural tube of origin. They u
APA, Harvard, Vancouver, ISO, and other styles
7

Chhabra, Seema, Smrity Sahu, Keshav Sharma, et al. "Th17/IL-17, Immunometabolism and Psoriatic Disease: A Pathological Trifecta." In Psoriasis [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102633.

Full text
Abstract:
The burgeoning arena of immunometabolism provides evidence of how cellular, as well as local (tissue)/systemic metabolic pathways, are playing an important role in controlling immunity and inflammation. An intricate and elaborate network of various metabolic circuits specifically glycolysis, fatty acid oxidation and synthesis and amino acid metabolism precisely generate metabolites that rewire the immune response. Psoriasis is a chronic progressive self-perpetuated “IL-17-centric” inflammatory disease characterized by the co-existence of autoimmune and autoinflammatory pathways. Metabolic resp
APA, Harvard, Vancouver, ISO, and other styles
8

Guido, William. "Development of Corticothalamic Projections." In The Cerebral Cortex and Thalamus, edited by Chinfei Chen. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/med/9780197676158.003.0053.

Full text
Abstract:
Abstract This chapter discusses the recent advances and current understanding of the development of corticothalamic projections. These projections arise from subpopulations of cortical neurons that reside in layers V and VI. Distinct in their pattern of thalamic innervation and function, descending projections from layers 5 and 6 also exhibit somewhat different developmental plans. The chapter focuses on their origin, cell fate, axon guidance, and layer-specific targeting of thalamic nuclei. The author also explores the impact that corticothalamic projections have on the development and plasti
APA, Harvard, Vancouver, ISO, and other styles
9

Traub, R. D., M. A. Whittington, and A. Draguhn. "Gap Junctions Between Pyramidal Cells Account for a Variety of Very Fast Network Oscillations (>80 Hz) in Cortical Structures." In Network Functions and Plasticity. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-803471-2.00013-8.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

"The Development of Form and Function in Fishes and the Question of Larval Adaptation." In The Development of Form and Function in Fishes and the Question of Larval Adaptation, edited by Ian A. Johnston and Thomas E. Hall. American Fisheries Society, 2004. http://dx.doi.org/10.47886/9781888569582.ch5.

Full text
Abstract:
<em>Abstract.</em>—Three phases of myogenesis have been identified in the myotomal muscles of larval teleosts. The commitment of embryonic slow and fast muscle lineages is determined prior to segmentation (embryonic myogenesis) and involves notochord and floorplate derived signaling pathways, which drive the adaxial cells to a slow muscle fate. The adaxial cells elongate to span the entire somite width and subsequently migrate through the myotome to form a superficial layer of slow muscle fibers. The remaining cells of the lateral mesoderm adopt the default fast muscle phenotype. T
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Cell fat plasticity"

1

Crawford, Howard C. "Abstract IA-18: Epithelial cell plasticity in pancreatic cancer: The function and fate of metaplastic tuft cells." In Abstracts: AACR Virtual Special Conference on Pancreatic Cancer; September 29-30, 2020. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.panca20-ia-18.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Scheel, C. "Abstract ES10-3: Cell fate plasticity during breast cancer development - where is the translational utility?" In Abstracts: 2019 San Antonio Breast Cancer Symposium; December 10-14, 2019; San Antonio, Texas. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.sabcs19-es10-3.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Blanpain, C. "Abstract ES10-1: Cellular Plasticity, Fate, Potential and Lineage Commitment of Mammary Gland Stem Cells." In Abstracts: 2019 San Antonio Breast Cancer Symposium; December 10-14, 2019; San Antonio, Texas. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.sabcs19-es10-1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Ozaltun, Hakan, and Barry H. Rabin. "Thermo-Mechanical Performance Assessment of Selected Plates From MP-1 High Power Experiments." In ASME 2017 Nuclear Forum collocated with the ASME 2017 Power Conference Joint With ICOPE-17, the ASME 2017 11th International Conference on Energy Sustainability, and the ASME 2017 15th International Conference on Fuel Cell Science, Engineering and Technology. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/nuclrf2017-3271.

Full text
Abstract:
Monolithic plate-type fuel is a fuel form that is being developed for the conversion of high performance research and test reactors to low-enrichment uranium fuels. These fuel-plates are comprised of a high density, low enrichment, U-Mo alloy based fuel foil encapsulated in an aluminum cladding. To benchmark this new design, number of plates has been irradiated with satisfactory performance. As a part of continuing evaluation efforts, a set of plates covering range of operational parameters is scheduled to be tested during MP-1 irradiation experiments. It is necessary to evaluate the thermo-me
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!