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Dissertations / Theses on the topic 'Cell Mediated Immunity (CMI)'

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1

Handy, Andrea Renee. "Acute Toxicity and Immunotoxicity Testing of Total Petroleum Hydrocarbons in Aquatic and Terrestrial Organisms." Wright State University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=wright1185910580.

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2

Abdel-Nour, A. N. "Cell mediated immunity in rheumatoid arthritis." Thesis, University of Bristol, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375007.

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3

Liew, F. Y. "Cell mediated-immunity against infectious diseases." Thesis, Canberra, ACT : The Australian National University, 1990. http://hdl.handle.net/1885/142999.

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4

Abdulahad, Wayel Habib. "T-cell mediated immunity in Wegener's granulomatosis." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2008. http://irs.ub.rug.nl/ppn/.

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5

McCafferty, Michael Campbell. "Ovine cell mediated immunity to Chlamydia psittaci." Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/20002.

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Enzootic Abortion of Ewes (EAE) is an economically important disease of ewes, caused by the gram negative, intracellular bacterium, <i>Chlamydia psittaci</i>. The disease results in lamb loss from abortion and the perinatal death of weak lambs. Vaccines have controlled EAE for more than thirty years, however in the last decade vaccine efficacy has been poor. The primary aim of this project was to examine the cell mediated immune responses to <i>C.psittaci</i> in sheep and to identify potentially immunoprotective antigens for future vaccine studies, by their ability to stimulate both T-cell pro
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6

Lindencrona, Jan Alvar. "Enhancing T cell mediated immunity in DNA vaccination /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-710-x.

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7

Lee, Laurel Yong-Hwa. "T cell mediated immunity to influenza in humans." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670049.

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8

Dobbs, Cathleen M. "Neuroendocrine modulation of anti-viral cell-mediated immunity /." The Ohio State University, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487941504294026.

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9

Podoba, John E. "Evidence for cell-mediated immunity to plasmodium chabaudi AS." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=55665.

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10

Chaudhry, Afzal Niaz. "Cell mediated immunity in the development of crescentic glomerulonephritis." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410025.

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11

Wilson, A. D. "Cell mediated immunity in the intestine of the pig." Thesis, University of Bristol, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375389.

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12

Jackson, Melany. "Cell mediated immunity in cutaneous infections with human papillomavirus." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/21322.

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This study investigated systemic and local cell mediated immunity to HPV in patients with cutaneous warts in order to understand the basis for their persistence or regression. The aim of the first part of the project was to examine HPV-specific lymphoproliferative responses from the peripheral blood of patients with cutaneous HPV infection. Proliferative T cell responses towards purified HPV <I>in vitro</I> were demonstrated in some individuals but frequently responses were weak or non existent. Patients whose warts were regressing (or had fully resolved) did not show increased lymphoprolifera
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13

Makobong'o, Morris Omollo. "Target antigens of cell-mediated immunity in Plasmodium yoelii /." [St. Lucia, Qld.], 2002. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16353.pdf.

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14

Arenas, Ricart J. "Maternal cell-mediated immunity to paternal HLA in human pregnancy." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371508.

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15

Ling, Khoon Lin. "Investigations into T cell mediated tumour immunity in the colon." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.422657.

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16

Duggan-Keen, M. F. "Human immunogenetic and cell-mediated immunity studies in selected diseases." Thesis, University of Newcastle Upon Tyne, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355072.

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17

Beck, Melinda Annetta. "Regulation of cell-mediated immunity during reinfection with influenza virus /." The Ohio State University, 1987. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487324944212867.

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18

Bruns, Nicholas Joseph. "Humoral and cell-mediated immunity in vitamin A-deficient lambs." Diss., Virginia Polytechnic Institute and State University, 1988. http://hdl.handle.net/10919/53919.

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Antigen-specific and polyclonal serum immunoglobulin G (IgG) concentrations were measured in control (Con), vitamin A-deficient (A-def), and vitamin A-repleted (A-rep) lambs. In Trial, I ewe lambs were injected with primary and secondary antigenic challenges of ovalbumin (1mg) and lysozyme (.1mg). The A-def lambs were then repleted with vitamin A and all lambs were injected with primary and secondary antigenic challenges of human gamma globulin (HGG) (.1mg). In Trial II Con and A-def wether lambs were given primary and secondary antigenic challenges of ovalbumin (20μg). Half of the A-def lambs
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19

Hu, Yong. "Altered T Cell-Mediated Immunity and Infectious Factors in Autism." DigitalCommons@USU, 2000. https://digitalcommons.usu.edu/etd/6846.

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Three major questions were addressed in this dissertation: 1)Do immune abnormalities associated with autism primarily alter CD4+ T cell-mediated or humoral immune responses? 2) Are specific T cell clones expanded in autism? 3) Which, if any, infectious agents play a role in autism? CD4+ T cell-mediated (Th1) or humoral (Th2) immune responses can be distinguished on the basis of the cytokines expressed. CD4+ T-cells secrete interleukin type 2 (IL-2) and interferon-γ, whereas a Th2 response is associated with secretion of interleukin type 4(IL-4). mRNA extracted from peripheral blood mononuclear
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20

Borysiewicz, L. K. "Cell mediated immunity to human cytomegalovirus infection (cytotoxic T cell and natural killer cell mediated lysis of human cytomegalovirus infected cells)." Thesis, Imperial College London, 1986. http://hdl.handle.net/10044/1/37949.

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21

Bradford, Hannah Elizabeth Linda. "Cell-mediated immunity to parainfluenza type 3 virus in young calves." Thesis, Queen's University Belfast, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334497.

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22

RODRIGUES, Olívia Roos. "Characterization and functional analysis of cell-mediated immunity to Leishmania infantum." Doctoral thesis, Instituto de Higiene e Medicina Tropical, 2009. http://hdl.handle.net/10362/62620.

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Leishmania infantum é o agente responsável pela leishmaniose visceral zoonótica, uma parasitose frequentemente caracterizada por alterações específicas da imunidade celular e parasitismo progressivo. Sabe-se actualmente que as células T reguladoras (Treg) são na verdade linfócitos T que se encontram directamente envolvidos na indução de mecanismos de imunossupressão da resposta imunológica durante infecções crónicas, como por exemplo Leishmania. Deste modo, este estudo tem como objectivo analisar o papel das Treg durante a infecção com L. infantum em modelo animal susceptível. Os resultados ob
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23

Bell, L. C. K. "Modulation of cell-mediated immunity by HIV-1 infection of macrophages." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1463526/.

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Cell-mediated immunity (CMI) is central to the host response to intracellular pathogens such as Mycobacterium tuberculosis (Mtb). The function of CMI can be modulated by human immunodeficiency virus (HIV)-1 via its pleiotropic effects on the immune response, including modulation of macrophages, which are parasitized by both HIV-1 and Mtb. HIV-1 infection is associated with increased risk of tuberculosis (TB), and so in this thesis I sought to explore the host/pathogen interactions through which HIV-1 dysregulates CMI, and thus changes the natural history of TB. Using an in vitro model of human
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24

Kotha, Jayaprakash. "Molecular mechanism of tetraspanin CD9 mediated cell motility." View the abstract Download the full-text PDF version, 2007. http://etd.utmem.edu/ABSTRACTS/2007-010-Kotha-index.html.

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Thesis (Ph.D. )--University of Tennessee Health Science Center, 2007.<br>Title from title page screen (viewed on July 16, 2007). Research advisor: Lisa K. Jennings, Ph.D. Document formatted into pages (xiv, 150 p. : ill.). Vita. Abstract. Includes bibliographical references (p.130-150).
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25

Hussein, S. M. Ali. "Adjuvants for synthetic peptide antigens." Thesis, University of Manchester, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.254102.

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26

Buffone, Vincent. "Polymorphonuclear leukocyte functions and cell mediated immunity in surgical and trauma patients." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=63177.

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27

Haßel, Silvana Katharina [Verfasser]. "Aptamers for targeted activation of T cell-mediated immunity / Silvana Katharina Haßel." Bonn : Universitäts- und Landesbibliothek Bonn, 2016. http://d-nb.info/1162953004/34.

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28

Fortes, Cristina Deppermann. "Zinc, vitamin A, cell-mediated immunity and infection in an elderly population." Thesis, University of London, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265006.

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29

Klemetti, Paula. "T-cell mediated immunity in the pathogenesis of insulin-dependent diabetes mellitus." Helsinki : University of Helsinki, 1999. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/klemetti/.

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30

Curry, Patrick Mark. "Cell-mediated tumour immunity following photodynamic therapy with benzoporphyrin derivative monoacid ring A." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ27127.pdf.

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31

Shaw, Iain. "The role of cell-mediated immunity in protection against infectious Bursal disease virus." Thesis, Royal Veterinary College (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285171.

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32

Agrawal, T. "Epithelial ErbB2 regulation of thymus homeostasis and age-associated T cell mediated immunity." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10048131/.

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The molecular mechanisms governing the functional and structural decline of thymus with age, causing thymic immunosenescence, are incompletely identified. Using a bitransgenic mouse model, Dr Giangreco discovered that the over-expression of receptor tyrosine kinase ErbB2 causes reversible thymic atrophy. The over-expression of epithelial ErbB2 upon doxycycline administration in bitransgenic mice led to decreased thymus size and cellularity, loss of cortical-medullary boundary and abnormal T cell differentiation, bearing similarity to age-dependent thymic involution. This thesis set out to inve
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33

Fernandes, Dancella Marie. "Cell-mediated immunity as the basis for resistance or susceptibility to murine brucellosis /." The Ohio State University, 1994. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487859313346275.

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34

Yeo, S. P. "Aspects of the development of cell-mediated immunity in the respiratory tract of the calf." Thesis, University of Bristol, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380219.

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35

O'Hara, Richard James. "Interleukin-12 a pivotal cytokine in cell mediated immunity : the role in colorectal cancer." Thesis, University of Hull, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.395426.

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36

Sugata, Kenji. "HTLV-1 bZIP factor impairs cell-mediated immunity by suppressing production of Th1 cytokines." Kyoto University, 2012. http://hdl.handle.net/2433/157444.

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37

Wang, Yang. "Murine adriamycin-induced nephropathy : the roles of cell-mediated immunity and CD4+ T-lymphocytes." Thesis, The University of Sydney, 2000. https://hdl.handle.net/2123/27827.

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38

柴山, 史朗. "IFN-α Directly Promotes Programmed Cell Death-1 Transcription and Limits the Duration of T Cell-Mediated Immunity". 京都大学, 2011. http://hdl.handle.net/2433/147347.

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39

Godoy, Ramirez Karina. "Flow cytometric methods for assessment of cell-mediated immune responses /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-409-0/.

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40

Xu, Dan. "Cellular Immunity in Recombinant Adeno-Associated Virus Vector Mediated Gene Therapy." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1313504203.

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41

Siddiqui, Mahveen. "Asymptomatic visceral leishmaniasis." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313394.

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42

Bauer, Moises Evandro. "Endocrine-immune interactions in major depression, acute and chronic stress." Thesis, University of Bristol, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266950.

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43

Essa, Sahar Sultan. "A study on the cell mediated immunity of human cytomegalovirus infection in kidney transplant recipients." Thesis, University of Warwick, 2001. http://wrap.warwick.ac.uk/59544/.

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Cytomegalovirus (CMV) infection is a major complication after kidney transplantation. Despite antiviral therapy it contributes significantly to high morbidity. This study was aimed at (a) detecting· a CMV specific antigen pp65 in CMV -infected fibroblast cells and in leukocytes of kidney transplant recipients by flow cytometric assay (FCA) (b) determining the stimulation index (S.I.) of phytohaemagglutinin (PHA) and CMV-stimulated peripheral blood mononuclear cells (PBMC), (c) determining the levels of Th1- and Th-2 related cytokines in the supernatant of stimulated PBMC from kidney transplant
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44

Mazahery, Claire. "CD8+ T Cell Mediated Immunity is Disrupted by Ex Vivo and In Vivo Opioid Use." Case Western Reserve University School of Graduate Studies / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=case1587376234022407.

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45

Taruselli, Marcela. "The Effect of Statins on IL-33 Mediated Mast Cell Function." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3926.

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This study demonstrates original findings of statin effects on IL-33 stimulated mast cells. Statins are a class of drugs used to lower cholesterol production by targeting HMG CoA reductase. These commonly prescribed drugs have been shown to be immunomodulatory. In this study, we have found that pretreatment with statins has a variety of effects on IL-33 stimulated mast cells. Atorvastatin suppresses TNF and IL-6 production, while fluvastatin significantly enhances release of these proinflammatory cytokines in BMMCs. Although they have differing effects on cytokine production, both statins lowe
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46

Taruselli, Marcela. "Fluvastatin and microRNA-146a alter interleukin-33 mediated mast cell functions." VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/5859.

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Mast cells are tissue-resident immune cells known as effector cells for the innate and adaptive immune systems. Mast cells contribute to host defenses against parasites such as large roundworm parasites, bacterial pathogens, and toxins, and participate in wound healing, but they are mostly known for their role in allergic diseases. It has been well established that during allergic diseases, mast cells are stimulated by IgE cross-linkage to release proinflammatory mediators. However, a newly discovered cytokine, IL-33 has also been implicated in allergic disease. Recently, IL-33 has been implic
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47

Kaveh, Daryan Alexander. "Mechanisms of BCG-induced CD4 T cell-mediated immunity against mycobacterium bovis in the BALB/c mouse." Thesis, St George's, University of London, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.676097.

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The only available tuberculosis vaccine is BCG, but this requires urgent replacement or improvement for more efficacious use in the prevention of the large burden of disease in both humans and cattle. The protection provided by BCG remains valuable and in order to facilitate further vaccine development, the underlying protective mechanisms require understanding. In this thesis the putative role of the CD4 T cell response was examined. Collectively it was shown that BCG immunisation of BALB/c mice led to their colonisation by the live BCG vaccine bacilli. By six weeks postimmunisation the vacci
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48

Izzo, Angelo Antonio. "A study of cell-mediated immunity in subjects vaccinated against Q fever and after Q fever infection /." Title page, contents and preface only, 1991. http://web4.library.adelaide.edu.au/theses/09PH/09phi99.pdf.

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49

Lee, Kit-ming, and 李潔明. "Study of cell-mediated immune response in mice against muscle phase ofinfection by Trichinella pseudospiralis (Nematoda)." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B29475387.

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50

Mayes, Kimberly. "The Role of the Nucleosome Remodeling Factor NURF in Inhibiting T and Natural Killer Cell Mediated Antitumor Immunity by Suppressing Tumor Antigenicity and Natural Cytotoxicity Receptor Co-ligands." VCU Scholars Compass, 2017. http://scholarscompass.vcu.edu/etd/4770.

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Tumor immunoediting is a dynamic process in which the immune response attacks tumor cells by detecting danger signals and tumor antigens. In order to survive, tumor cells develop mechanisms to avoid detection or destruction by the immune system. To counteract this, several strategies are being developed to enhance the antitumor immune response, including the depletion of immunosuppressive cells, enhancing the activation of antitumor immune cells and increasing tumor cell immunogenicity. These therapies have seen limited success individually, however, and it is likely that combination therapy w
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