Academic literature on the topic 'Cell migration strategies'

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Journal articles on the topic "Cell migration strategies"

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Kameritsch, Petra, and Jörg Renkawitz. "Principles of Leukocyte Migration Strategies." Trends in Cell Biology 30, no. 10 (2020): 818–32. http://dx.doi.org/10.1016/j.tcb.2020.06.007.

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Krummel, Matthew F., Frederic Bartumeus, and Audrey Gérard. "T cell migration, search strategies and mechanisms." Nature Reviews Immunology 16, no. 3 (2016): 193–201. http://dx.doi.org/10.1038/nri.2015.16.

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Kummerow, Carsten, Hélène Lyrmann, Marc Neef, et al. "Modeling Killer Cell Migration and Search Strategies." Biophysical Journal 104, no. 2 (2013): 320a. http://dx.doi.org/10.1016/j.bpj.2012.11.1773.

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Hatzikirou, H., K. Böttger, and A. Deutsch. "Model-based Comparison of Cell Density-dependent Cell Migration Strategies." Mathematical Modelling of Natural Phenomena 10, no. 1 (2015): 94–107. http://dx.doi.org/10.1051/mmnp/201510105.

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Painter, K. J. "Modelling cell migration strategies in the extracellular matrix." Journal of Mathematical Biology 58, no. 4-5 (2008): 511–43. http://dx.doi.org/10.1007/s00285-008-0217-8.

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Baeyens, Audrey, Victoria Fang, Cynthia Chen, and Susan R. Schwab. "Exit Strategies: S1P Signaling and T Cell Migration." Trends in Immunology 36, no. 12 (2015): 778–87. http://dx.doi.org/10.1016/j.it.2015.10.005.

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Isabelle Comte, Phuong B. Tran, and Francis G. Szele. "Techniques and Strategies to Analyze Neural Progenitor Cell Migration." Current Pharmaceutical Biotechnology 8, no. 3 (2007): 177–85. http://dx.doi.org/10.2174/138920107780906513.

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Li, Gaigai, Yang Hu, Yanfang Chen, and Zhouping Tang. "Strategies to Improve the Migration of Mesenchymal Stromal Cells in Cell Therapy." Translational Neuroscience and Clinics 3, no. 3 (2017): 159–75. http://dx.doi.org/10.18679/cn11-6030_r.2017.025.

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Mesenchymal stromal/stem cells (MSCs) are multipotent cells under consideration as a potential new therapy for a variety of inflammatory diseases including certain neurological disorders. It is generally thought that the efficacy of cell therapy in attenuating damage after ischemia, inflammation, or injury depends on the quantity of transplanted cells recruited to the target tissue. However, only a small number of systematically infused MSCs can effectively migrate to target sites, which significantly decreases the efficacy of exogenous cell-based therapy. In this review, we discuss specific f
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Li, Gaigai, Gaigai Li, Yang Hu, et al. "Strategies to improve the migration of mesenchymal stromal cells in cell therapy." Translational Neuroscience and Clinics 3, no. 3 (2017): 159–75. http://dx.doi.org/10.18679/cn11-6030/r.2017.025.

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Friedl, P., E. B. Bröcker, and K. S. Zänker. "Integrins, Cell Matrix Interactions and Cell Migration Strategies: Fundamental Differences in Leukocytes and Tumor Cells." Cell Adhesion and Communication 6, no. 2-3 (1998): 225–36. http://dx.doi.org/10.3109/15419069809004478.

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Dissertations / Theses on the topic "Cell migration strategies"

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Hatzikirou, H., K. Böttger, and A. Deutsch. "Model-based Comparison of Cell Density-dependent Cell Migration Strategies." Cambridge University Press, 2015. https://tud.qucosa.de/id/qucosa%3A39048.

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Here, we investigate different cell density-dependent migration strategies. In particular, we consider strategies which differ in the precise regulation of transitions between resting and motile phenotypes. We develop a lattice-gas cellular automaton (LGCA) model for each migration strategy. Using a mean-field approximation we quantify the corresponding spreading dynamics at the cell population level. Our results allow for the prediction of cell population spreading based on experimentally accessible single cell migration parameters.
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Wolf, Katarina. "Migration of tumor cells and leukocytes in extracellular matrix proteolytic and nonproteolytic strategies for overcoming tissue barriers /." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=971018243.

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Ramakrishna, Edukulla. "Strategies for improved cancer virotherapy in vivo migration and expansion of dendritic cells enhance cross-presentation of tumor antigens in virotherapy /." kostenfrei, 2008. http://d-nb.info/98826448X/34.

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Wolf, Katarina. "Migration of tumor cells and leukocytes in extracellular matrix : proteolytic and nonproteolytic strategies for overcoming tissue barriers." Doctoral thesis, 2002. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-5670.

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The extracellular matrix within connective tissues represents a structural scaffold as well as a barrier for motile cells, such as invading tumor cells or passenger leukocytes. It remains unclear how different cell types utilize matrix-degrading enzymes for proteolytic migration strategies and, on the other hand, non-proteolytic strategies to overcome 3D fibrillar matrix networks. To monitor cell migration, a 3D collagen model in vitro or the mouse dermis in vivo were used, in combination with time-lapse video-, confocal- or intravital multiphoton-microscopy, and computer-assisted cell trackin
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Wolf, Katarina [Verfasser]. "Migration of tumor cells and leukocytes in extracellular matrix : proteolytic and nonproteolytic strategies for overcoming tissue barriers / vorgelegt von Katarina Wolf." 2003. http://d-nb.info/971018243/34.

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Ramakrishna, Edukulla [Verfasser]. "Strategies for improved cancer virotherapy : in vivo migration and expansion of dendritic cells enhance cross-presentation of tumor antigens in virotherapy / von Edukulla Ramakrishna." 2008. http://d-nb.info/98826448X/34.

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Books on the topic "Cell migration strategies"

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Banjara, Manoj, and Damir Janigro. Effects of the Ketogenic Diet on the Blood-Brain Barrier. Edited by Detlev Boison. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190497996.003.0030.

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Ketone bodies (KBs) are always present in the blood, and their levels increase after high-fat diet intake, prolonged exercise, or extended fasting. Thus, one can predict effects on the brain capillary endothelium from high levels of ketones in the blood. Prolonged exposure of blood-brain barrier (BBB) endothelial cells to KBs induces expression of monocarboxylate transporters and enhances brain uptake of KBs. In addition, cell migration and expression of gap junction proteins are up-regulated by KBs. Thus, beneficial effects of the ketogenic diet may depend on increased brain uptake of KBs to
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Ali, Ased. Pathogenesis of urinary tract infection. Edited by Rob Pickard. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0001.

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The realization of the harms resulting from indiscriminate use of antibiotics for minor infection has added impetus to the need to understand better the interaction between urogenital tract epithelium and invading bacteria during the initial stages of urinary tract infection (UTI). It is thought that uropathogenic Escherichia coli clones develop in the gut and migrate across the perineum to the urethra and up into the bladder. The response of the epithelium to bacterial adherence and the evolution of the invading bacteria will then govern the clinical consequences. These can vary between rapid
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Book chapters on the topic "Cell migration strategies"

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Chen, Yuhui, Gianpietro Dotti, and Barbara Savoldo. "Strategies to Enhance Migration and Persistence of Chimeric Antigen Receptor (CAR)-T Cells into Tumors." In Resistance to Targeted Anti-Cancer Therapeutics. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-42223-7_8.

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Espinosa-Jeffrey, Araceli, Karlos Oregel, Laurent Wiggins, et al. "Strategies for Endogenous Spinal Cord Repair: HPMA Hydrogel to Recruit Migrating Endogenous Stem Cells." In Advances in Experimental Medicine and Biology. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-4090-1_3.

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Saltzman, W. Mark. "Cell Migration." In Tissue Engineering. Oxford University Press, 2004. http://dx.doi.org/10.1093/oso/9780195141306.003.0012.

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Cell migration is crucial to the life of unicellular and multicellular organisms. Unicellular organisms migrate to find food and avoid predators; this migration can occur by swimming through a fluid, which is achieved by flagellar or ciliary beating (exemplified by E. coli or Paramecium, respectively), or crawling along a surface (as in amoebae). In multicellular organisms, migration of a particular cell population is often a component of complex multicellular behaviors including tumor invasion and metastasis, embryogenesis, angiogenesis, and immune responses. In both cases, the speed and pattern of migration are determined by the nature of the cell and by chemicals (both soluble and surface-bound) in the environment. Since cell migration is critical in the formation or regeneration of tissues, a clearer understanding of the dynamics of cell migration would greatly enhance our ability to design materials and processes for tissue engineering. Cell migration is a fundamental mechanism for forming of structures within developing embryos. Accordingly, the migration of cells during embryogenesis is under exquisite control; development of tissue structure and cell migration are interdependent. Chapter 3 discussed limb regeneration in salamanders, a process in which positional gradients of cell adhesion influence cell migration and, ultimately, tissue structure. Similarly, the rate and migration of myogenic cells from the somitic mesoderm is influenced by the presence of local signals in the form of diffusible factors and extracellular matrix composition. These local signals are also produced by cells, with the result that cells throughout the developing limb (which are present in a particular arrangement or tissue structure) control and coordinate the migration of myogenic cells by secretion of activating factors and expression or organization of extracellular matrix molecules. A better understanding of the mechanisms underlying cell migration in the embryo, and the strategies that nature uses to control migration, will almost certainly provide inspiration for tissue engineering. Cell migration underlies many important physiological functions in adults. For example, the immune system, with its widely dispersed ensemble of B and T cells, relies heavily on the coordinated migration of individual cells to patrol the body and to provide opportunities for cell–cell interaction.
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Deleanu, Roxana. "Human Pluripotent Stem Cell-Derived Cerebellar Neurons: From Development to Modeling Cerebellar Ataxias." In Spinocerebellar Ataxia [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96653.

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The most affected cell types in cerebellar ataxias are the cerebellar neurons, which are not readily accessible for cellular and molecular investigation. Pluripotent stem cell (PSC) technology has emerged as an important tool for generating diverse types of neurons, which are used in order to better understand the human nervous system development and pathologies. In this chapter, the strategies for the differentiation of human PSCs toward cerebellar neurons are overviewed, followed by an outlook of their further optimization and diversification by implementing the knowledge from cerebellar development and new cell culture approaches. The optimization stategies are based on the recent progress made in defining the cell populations in mature and developing mouse and human cerebellum. The cellular phenotypes and organization in mouse and human cerebellum are briefly presented, followed by an overview of our current knowledge about their development, which includes pattering, proliferation, neurogenesis, gliogenesis, migration, connectivity and maturation. To date, however, relatively few studies have used induced PSCs (iPSCs) to model cerebellar ataxias and even fewer have looked directly to cerebellar neurons. The reported iPSC-derived in vitro models for cerebellar ataxias are reviewed, followed by an outlook of how to improve these models by generating and exporing the cerebellar neurons.
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Auguet, Teresa, Laia Bertran, and Jessica Binetti. "Intestinal Dysbiosis and Non-Alcoholic Fatty Liver Disease." In Human Microbiome. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.92972.

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Non-alcoholic fatty liver disease (NAFLD) affects 20–30% of the population, with an increased prevalence in industrialized regions. Some patients with NAFLD develop an inflammatory condition termed non-alcoholic steatohepatitis (NASH) that is characterized by hepatocellular injury, innate immune cell-mediated inflammation, and progressive liver fibrosis. In clinical practice, abdominal imaging, which reveals hepatic steatosis, is sufficient for NAFLD diagnosis if other diseases have been rejected. However, a liver biopsy is needed to differentiate NASH from simple steatosis. Therapeutic strategies used to treat obesity and metabolic syndrome improve NAFLD, but there is no specific treatment effective for NASH. The gut microbiota (GM) is composed of millions of microorganisms. Changes in the GM have a significant impact on host health. Intestinal dysbiosis is an imbalance in the GM that can induce increased permeability of the epithelial barrier, with migration of GM-derived mediators through portal vein to the liver. These mediators, such as lipopolysaccharides, short-chain fatty acids, bile acids (BAs), choline, and endogenous ethanol, seem to be involved in NAFLD pathogenesis. Given this evidence, it would be interesting to consider GM-derived mediator determination through omics techniques as a noninvasive diagnostic tool for NASH and to focus research on microbiota modulation as a possible treatment for NASH.
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Kumar, K. S. Kavi, and Brinda Viswanathan. "Mainstreaming Climate Change Adaptation." In India in a Warming World. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780199498734.003.0028.

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This chapter provides an overview of issues surrounding the mainstreaming of climate change adaptation in the agriculture sector with focus on India. The status of adaptation research focusing on triggers of adaptation and adaptation strategies, such as innovation, adoption of technologies, risk management, and migration, are discussed. The chapter then deliberates on approaches for mainstreaming climate change adaptation policies, namely, climate-proofing, climate-first, and development-first. The wide-ranging budgetary requirements made by the State Action Plans on Climate Change for the agricultural sector highlight the need for a coherent approach for assessing adaptation budgets, along with the establishment of climate and disaster cells in the line departments of the state governments to integrate the climate risks with the developmental plans.
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Anderson, Sharon J. "Proton and 19F NMR Spectroscopy of Pesticide Intermolecular Interactions." In Nuclear Magnetic Resonance Spectroscopy in Environment Chemistry. Oxford University Press, 1997. http://dx.doi.org/10.1093/oso/9780195097511.003.0008.

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Sorption of organic pollutants by soils and sediments is one of the main chemical processes that controls pollutant migration in the environment. Information about the molecular mechanisms by which an organic pollutant interacts with other solution-phase constituents and with solid-phase sorbents would be invaluable for more accurate prediction of pollutant fate and transport and for optimal design and application of remediation procedures. Many current models and remediation strategies are based upon the “partition theory” of organic compound sorption, which predicts sorption coefficients from properties such as water solubility or octanol-water partition coefficients. Partition theory is well suited for nonpolar hydrocarbons but may not be appropriate for pesticides with electrophilic or weakly acidic or basic substituents, which may interact with soils or organic matter through specific interactions such as hydrogen bonding or charge-transfer complexes. If a pesticide can form hydrogen bonds or a charge-transfer complex with a sorbent, sorption may be greater than in the absence of specific interactions. Nuclear magnetic resonance (NMR) spectroscopy is well suited for the study of pesticide-solution or pesticide-sorbent interactions because NMR is an element-specific method that is extremely sensitive to the electron density (shielding) near the nucleus of interest. Consequently, solution-state NMR can distinguish between closely related functional groups and can provide information about intermolecular interactions. All nuclei with nonzero nuclear spin quantum number can be studied by NMR spectroscopy. Of the more than 100 NMR-active nuclei, 1H and 19F are the easiest to study because both have natural abundances near 100% and greater NMR sensitivity than any other nuclei. In addition, both 1H and 19F have zero quadrupolar moments, which means that sharp, well resolved NMR peaks can be obtained, at least in homogeneous solutions. Proton NMR is well suited for elucidating molecular interactions in solution but cannot be used to study interactions between pesticides and heterogeneous sorbents such as soils, humic acid, or even cell extracts, since protons in the sorbent generally produce broad peaks that mask the NMR peaks from the solute or sorbate of interest. In contrast, 19F NMR can be used to study interactions between fluorine-containing molecules and heterogeneous sorbents because the fluorine concentration in most natural sorbents is negligible.
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Conference papers on the topic "Cell migration strategies"

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Tan, Andrea R., Elena Alegre-Aguarón, Divya N. Dujari, et al. "Effects of Passaging on the Migration Response of Synovium-Derived Stem Cells to an Applied DC Electric Field." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53674.

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Strategies for cartilage tissue engineering and repair have recently focused on cell sources from the surrounding joint tissue as an alternative to chondrocytes. Synovium-derived stem cells (SDSCs) are found in the intimal layer of the synovium, the thin overlying capsule surrounding the joint space [1] and have been found to exhibit a greater chondrogenic potential than stem cells from other origins such as bone marrow stem cells or adipose derived stem cells [2–4]. Under directed cues, these cells have been shown to be capable of migrating from the synovium membrane into articular cartilage
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Cheng, Yu-Chen, and Pen-Hsiu Grace Chao. "A Model for Ligament Fibroblast Migration Into Provisional Matrix." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53858.

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Many strategies have been proposed to enhance the healing capability of the anterior cruciate ligament (ACL). A novel treatment option, called enhanced primary repair, places a provisional matrix at the tear site to promote cell infiltration of the wound and aims to reestablish the structure-function relationship of the ACL [1]. This approach of guided tissue regeneration offers great potential benefits of retaining the complex native tissue matrix structure, innervation, and vascularization as compared with grafts. A major aspect of this procedure is enhancing ligament fibroblast infiltration
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Guvendiren, Murat, and Jason A. Burdick. "Dynamic Mechanical Properties Control Adult Stem Cell Fate." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80062.

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Stem cells respond to many microenvironmental cues towards their decisions to spread, migrate, and differentiate and these cues can be incorporated into materials for regenerative medicine.1 In the last decade, matrix stiffness alone has been implicated in regulating cellular functions such as migration, proliferation and differentiation. With this in mind, a variety of natural and synthetic polymer systems were used in vitro to mimic the elasticity of native tissues. Despite helping to develop this important field and gather valuable information, these substrates are primarily static and lack
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Zhang, Zheming, and Ramesh Agarwal. "Numerical Simulation of Geological Carbon Sequestration in Saline Aquifers: Three Case Studies." In ASME 2013 7th International Conference on Energy Sustainability collocated with the ASME 2013 Heat Transfer Summer Conference and the ASME 2013 11th International Conference on Fuel Cell Science, Engineering and Technology. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/es2013-18025.

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Geological carbon sequestration (GCS) is one of the most promising technologies to address the issue of excessive anthropogenic CO2 emissions in the atmosphere due to fossil fuel combustion for electricity generation. For GCS, the saline aquifer geological carbon sequestration is considered very attractive compared to other options because of their huge sequestration capacity in U.S. and other parts of the world. However, in order to fully exploit their potential, the injection strategies need to be investigated that can address the issues of both the CO2 storage efficiency and safety along wi
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Tran, Phat L., Jessica R. Gamboa, Katherine E. McCracken, Jeong-Yeol Yoon, and Marvin J. Slepian. "Interaction With Nanoscale Topography: The Use of Nanowell-Trapped Charged Ligand-Bearing Nanoparticle Surfaces To Modulate Physiological Focal Adhesions in Endothelial Cells." In ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/nemb2013-93345.

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Achieving cell adhesion, growth and homeostasis on an underlying biomaterial surface may be a desirable feature in implant device design and tissue engineering. Insight has been gained from numerous cell patterning strategies where spatial cues and physical constraints have been shown to regulate the structure and function of cells. Despite significant advances in modifying substrates for cellular attachment, migration and proliferation, the achievement of confluent and aligned growth of functional endothelial cells on cardiovascular blood-contacting implants under physiologically significant
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Tanguay, Robert L., Lisa Truong, Tatiana Zaikova, and James E. Hutchison. "Rapid In Vivo Assessment of the Nano/Bio Interface." In ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/nemb2013-93153.

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Recent advances in nanoscience offer great promise for the nanomedicine sector. These advances in the nanotechnology field will undoubtedly increase both human and environmental exposures to engineered nanomaterials. Whether these exposures pose a significant risk remains uncertain. Despite recent collective progress there remain gaps in our understanding of the nanomaterials physiochemical properties that drive or dictate biological compatibility. The development and implementation of rapid relevant and efficient testing strategies to assess these emerging materials prior to large-scale expos
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CONDRATOV, Iulian Alexandru. "A Cross-Region Panel Analysis of the Migration in Romania." In The 14th Economic International Conference: Strategies and Development Policies of Territories: International, Country, Region, City, Location Challenges, May 10-11, 2018, Stefan cel Mare University of Suceava, Romania. LUMEN Publishing House, 2018. http://dx.doi.org/10.18662/lumproc.57.

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