Academic literature on the topic 'Cell Signaling - Carbohydrate Functionalized Nanomaterials'

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Journal articles on the topic "Cell Signaling - Carbohydrate Functionalized Nanomaterials"

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Rabiee, Navid, Sepideh Ahmadi, Siavash Iravani, and Rajender S. Varma. "Functionalized Silver and Gold Nanomaterials with Diagnostic and Therapeutic Applications." Pharmaceutics 14, no. 10 (2022): 2182. http://dx.doi.org/10.3390/pharmaceutics14102182.

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The functionalization of nanomaterials with suitable capping ligands or bioactive agents is an interesting strategy in designing nanosystems with suitable applicability and biocompatibility; the physicochemical and biological properties of these nanomaterials can be highly improved for biomedical applications. In this context, numerous explorations have been conducted in the functionalization of silver (Ag) and gold (Au) nanomaterials using suitable functional groups or agents to design nanosystems with unique physicochemical properties such as excellent biosensing capabilities, biocompatibili
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Neagu, Anca-Narcisa, Taniya Jayaweera, Krishan Weraduwage, and Costel C. Darie. "A Nanorobotics-Based Approach of Breast Cancer in the Nanotechnology Era." International Journal of Molecular Sciences 25, no. 9 (2024): 4981. http://dx.doi.org/10.3390/ijms25094981.

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We are living in an era of advanced nanoscience and nanotechnology. Numerous nanomaterials, culminating in nanorobots, have demonstrated ingenious applications in biomedicine, including breast cancer (BC) nano-theranostics. To solve the complicated problem of BC heterogeneity, non-targeted drug distribution, invasive diagnostics or surgery, resistance to classic onco-therapies and real-time monitoring of tumors, nanorobots are designed to perform multiple tasks at a small scale, even at the organelles or molecular level. Over the last few years, most nanorobots have been bioengineered as biomi
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Condorelli, Marcello, Antonio Speciale, Francesco Cimino, et al. "Nano-Hybrid Au@LCCs Systems Displaying Anti-Inflammatory Activity." Materials 15, no. 10 (2022): 3701. http://dx.doi.org/10.3390/ma15103701.

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Gold nanoparticles (Au NPs) have received great attention owing to their biocompatible nature, environmental, and widespread biomedical applications. Au NPs are known as capable to regulate inflammatory responses in several tissues and organs; interestingly, lower toxicity in conjunction with anti-inflammatory effects was reported to occur with Au NPs treatment. Several variables drive this benefit-risk balance, including Au NPs physicochemical properties such as their morphology, surface chemistry, and charge. In our research we prepared hybrid Au@LCC nanocolloids by the Pulsed Laser Ablation
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Giraldo, Juan Pablo. "(Invited) Carbon Nanostructures for Targeted Delivery and Health Monitoring in Plants." ECS Meeting Abstracts MA2024-01, no. 8 (2024): 863. http://dx.doi.org/10.1149/ma2024-018863mtgabs.

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To meet the demand for food and bioenergy of a rapidly growing global population requires novel and convergent approaches to enhance photosynthetic organism function. Nanotechnology is enabling the development of targeted and species independent tools for advancing plant bioengineering and precision agriculture. My research group has developed carbon nanotube-based sensors capable of real-time sensing of plant signaling molecules. These nanosensors enabled the creation of plant sentinels that communicate the health status of plants to electronic devices. Near-infrared (nIR) fluorescent single-
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Sharda, Deepinder, Pawandeep Kaur, and Diptiman Choudhury. "Protein-modified nanomaterials: emerging trends in skin wound healing." Discover Nano 18, no. 1 (2023). http://dx.doi.org/10.1186/s11671-023-03903-8.

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AbstractProlonged inflammation can impede wound healing, which is regulated by several proteins and cytokines, including IL-4, IL-10, IL-13, and TGF-β. Concentration-dependent effects of these molecules at the target site have been investigated by researchers to develop them as wound-healing agents by regulating signaling strength. Nanotechnology has provided a promising approach to achieve tissue-targeted delivery and increased effective concentration by developing protein-functionalized nanoparticles with growth factors (EGF, IGF, FGF, PDGF, TGF-β, TNF-α, and VEGF), antidiabetic wound-healin
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Qin, Xiaoyan, Yixin Wu, Shuang Liu, et al. "Surface Modification of Polycaprolactone Scaffold With Improved Biocompatibility and Controlled Growth Factor Release for Enhanced Stem Cell Differentiation." Frontiers in Bioengineering and Biotechnology 9 (January 7, 2022). http://dx.doi.org/10.3389/fbioe.2021.802311.

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Polycaprolactone (PCL) has been widely used as a scaffold material for tissue engineering. Reliable applications of the PCL scaffolds require overcoming their native hydrophobicity and obtaining the sustained release of signaling factors to modulate cell growth and differentiation. Here, we report a surface modification strategy for electrospun PCL nanofibers using an azide-terminated amphiphilic graft polymer. With multiple alkylation and pegylation on the side chains of poly-L-lysine, stable coating of the graft polymer on the PCL nanofibers was achieved in one step. Using the azide-alkyne “
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Koeksoy, Elif, Oliver M. Bezuidt, Timm Bayer, Clara S. Chan, and David Emerson. "Zetaproteobacteria Pan-Genome Reveals Candidate Gene Cluster for Twisted Stalk Biosynthesis and Export." Frontiers in Microbiology 12 (June 18, 2021). http://dx.doi.org/10.3389/fmicb.2021.679409.

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Twisted stalks are morphologically unique bacterial extracellular organo-metallic structures containing Fe(III) oxyhydroxides that are produced by microaerophilic Fe(II)-oxidizers belonging to the Betaproteobacteria and Zetaproteobacteria. Understanding the underlying genetic and physiological mechanisms of stalk formation is of great interest based on their potential as novel biogenic nanomaterials and their relevance as putative biomarkers for microbial Fe(II) oxidation on ancient Earth. Despite the recognition of these special biominerals for over 150 years, the genetic foundation for the s
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Rosato, Francesca, Rajeev Pasupuleti, Jana Tomisch, et al. "A bispecific, crosslinking lectibody activates cytotoxic T cells and induces cancer cell death." Journal of Translational Medicine 20, no. 1 (2022). http://dx.doi.org/10.1186/s12967-022-03794-w.

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Abstract Background Aberrant glycosylation patterns play a crucial role in the development of cancer cells as they promote tumor growth and aggressiveness. Lectins recognize carbohydrate antigens attached to proteins and lipids on cell surfaces and represent potential tools for application in cancer diagnostics and therapy. Among the emerging cancer therapies, immunotherapy has become a promising treatment modality for various hematological and solid malignancies. Here we present an approach to redirect the immune system into fighting cancer by targeting altered glycans at the surface of malig
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Dissertations / Theses on the topic "Cell Signaling - Carbohydrate Functionalized Nanomaterials"

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SK, Basiruddin. "Synthesis of Carbohydrate Functionalized Nanomaterials for Biomedical Application." Thesis, 2019. http://hdl.handle.net/10821/8254.

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Carbohydrate functionalized nanomaterials have emergent application potential in the field of biological science. Carbohydrates are the most abundant biomolecules in the living body and are present in the form of glycoprotein, glycolipid and various other complex structures. They play an important role in cell–cell communication, cell signaling and metastasis of cancer cell. Some carbohydrate receptors are over expressed in certain cancer cells. These receptors can be used for selective cancer targeting and therapy by using carbohydrate functionalized nanomaterials. Carbohydrate functionalized
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