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Journal articles on the topic 'Cell Viability'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Deniz, Özdemir. "KAN0438757: A NOVEL PFKFB3 INHIBITOR THAT INDUCES PROGRAMMED CELL DEATH AND SUPPRESSES CELL MIGRATION IN NON-SMALL CELL LUNG CARCINOMA CELLS." Biotechnologia Acta 16, no. 5 (2023): 34–44. http://dx.doi.org/10.15407/biotech16.05.034.

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Aim. PFKFB3 is glycolytic activators that is overexpressed in human lung cancer and plays a crucial role in multiple cellular functions including programmed cell death. Despite the many small molecules described as PFKFB3 inhibitors, some of them have shown disappointing results in vitro and in vivo. On the other hand KAN0438757, selective and potent, small molecule inhibitor has been developed. However, the effects of KAN0438757, in non-small cell lung carcinoma cells remain unknown. Herein, we sought to decipher the effect of KAN0438757 on proliferation, migration, DNA damage, and programmed

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2

Callender, Stephen C. "Cell Counts and Viability." Laboratory Medicine 17, no. 3 (1986): 167–68. http://dx.doi.org/10.1093/labmed/17.3.167.

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3

Braun, László, Tamás Garzó, Pál Riba, József Mandl, and Miklós Péter Kalapos. "Methylglyoxal and cell viability." International Journal of Biochemistry 26, no. 8 (1994): 987–90. http://dx.doi.org/10.1016/0020-711x(94)90069-8.

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4

Wei, Qi, Venkatesh Hariharan, and Hayden Huang. "Cell-Cell Contact Preserves Cell Viability via Plakoglobin." PLoS ONE 6, no. 10 (2011): e27064. http://dx.doi.org/10.1371/journal.pone.0027064.

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5

Chung, Jon H., Yonggang Zhang, and Fred Bunz. "Checkpoint bypass and cell viability." Cell Cycle 9, no. 11 (2010): 2102–7. http://dx.doi.org/10.4161/cc.9.11.11849.

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6

Shaw, Andrew J. "Defining Cell Viability and Cytotoxicity." Alternatives to Laboratory Animals 22, no. 2 (1994): 124–26. http://dx.doi.org/10.1177/026119299402200206.

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7

Lomakina, G. Yu, Yu A. Modestova, and N. N. Ugarova. "Bioluminescence assay for cell viability." Biochemistry (Moscow) 80, no. 6 (2015): 701–13. http://dx.doi.org/10.1134/s0006297915060061.

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8

Dvela, Moran, Haim Rosen, Hagit Cohen Ben-Ami, and David Lichtstein. "Endogenous ouabain regulates cell viability." American Journal of Physiology-Cell Physiology 302, no. 2 (2012): C442—C452. http://dx.doi.org/10.1152/ajpcell.00336.2011.

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The endogenous cardiac steroid-like compounds, endogenous ouabain (EO) in particular, are present in the human circulation and are considered putative ligands of the inhibitory binding site of the plasma membrane Na+-K+-ATPase. A vast amount of data shows that, when added to cell cultures, these steroids promote the growth of cardiac, vascular, and epithelial cells. However, the involvement of the endogenous compounds in the regulation of cell viability and proliferation has never been addressed experimentally. In this study, we show that EO is present in mammalian sera and cerebral spinal flu

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9

Topley, Nicholas, Tomasz Liberek, Chandra Mistry, Gerald A. Coles, and John D. Williams. "Cell Function, Viability, and Icodextrin." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 14, no. 2_suppl (1994): 28–32. http://dx.doi.org/10.1177/089686089401402s04.

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The bioincompatibility of conventional dialysis fluids is related primarily to the combination of low pH and high lactate concentrations. This results in the reduction of intracellular pH and a consequent inhibition of cell function. The use of high glucose concentrations to increase fluid osmolality adds to the cytotoxicity and has a further inhibitory effect on peritoneal cells. The clinical need for fluids that provide sustained ultrafiltration has led to a novel approach using a high molecular weight glucose polymer (icodextrin) to generate an ultrafiltration gradient in an iso-osmolar flu

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10

Marrack, Philippa, and John Kappler. "Control of T Cell Viability." Annual Review of Immunology 22, no. 1 (2004): 765–87. http://dx.doi.org/10.1146/annurev.immunol.22.012703.104554.

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11

Demuth, Caspar, Iris Poggendorf, Ruma Lüthi, Marlene Frank, and Kelsey McNeel. "Cell Viability in Real Time." Genetic Engineering & Biotechnology News 36, no. 12 (2016): 22–23. http://dx.doi.org/10.1089/gen.36.12.13.

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12

Kamiloglu, Senem, Gulce Sari, Tugba Ozdal, and Esra Capanoglu. "Guidelines for cell viability assays." Food Frontiers 1, no. 3 (2020): 332–49. http://dx.doi.org/10.1002/fft2.44.

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13

WAGNER, Stephanie, Jakob POHL, and Steffen HACKBARTH. "Cell Viability Under Anoxic Conditions." Photodiagnosis and Photodynamic Therapy 41 (March 2023): 103460. http://dx.doi.org/10.1016/j.pdpdt.2023.103460.

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14

Madorran, Eneko, Andraž Stožer, Zoran Arsov, Uroš Maver, and Jan Rožanc. "A Promising Method for the Determination of Cell Viability: The Membrane Potential Cell Viability Assay." Cells 11, no. 15 (2022): 2314. http://dx.doi.org/10.3390/cells11152314.

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Determining the viability of cells is fraught with many uncertainties. It is often difficult to determine whether a cell is still alive, approaching the point of no return, or dead. Today, there are many methods for determining cell viability. Most rely on an indirect determination of cell death (metabolism, molecular transport, and leakage, to name a few). In contrast, we have developed a promising novel method for a “direct” determination of cell viability. The potential method assesses cell membrane integrity (which is essential for all viable cells) by measuring the electrical potential of

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15

THURET, G., Z. HE, N. CAMPOLMI, et al. "Endothelial cell viability of endothelial lenticules." Acta Ophthalmologica 90 (August 6, 2012): 0. http://dx.doi.org/10.1111/j.1755-3768.2012.1634.x.

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16

Vremec, David, Jacinta Hansen, Andreas Strasser, et al. "Maintaining dendritic cell viability in culture." Molecular Immunology 63, no. 2 (2015): 264–67. http://dx.doi.org/10.1016/j.molimm.2014.07.011.

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17

Plate, Janet. "Signals that maintain leukemic cell viability." Blood 112, no. 1 (2008): 1–2. http://dx.doi.org/10.1182/blood-2008-03-144089.

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18

Kerr, Ellyn. "Cell Viability & Responsiveness in Assays." Genetic Engineering & Biotechnology News 31, no. 14 (2011): 26–29. http://dx.doi.org/10.1089/gen.31.14.11.

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19

Yang, H. "In situ assessment of cell viability." Cell Transplantation 7, no. 5 (1998): 443–51. http://dx.doi.org/10.1016/s0963-6897(98)00032-3.

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20

Browne, Susan M., and Mohamed Al-Rubeai. "Defining viability in mammalian cell cultures." Biotechnology Letters 33, no. 9 (2011): 1745–49. http://dx.doi.org/10.1007/s10529-011-0644-2.

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21

Armiger, L. C. "Cell viability in cryopreserved heart valves." New Zealand Veterinary Journal 41, no. 1 (1993): 43. http://dx.doi.org/10.1080/00480169.1993.36522.

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22

Darlington, G. J. "Viability Staining of Mammalian Cell Cultures." Cold Spring Harbor Protocols 2007, no. 12 (2007): pdb.prot4769. http://dx.doi.org/10.1101/pdb.prot4769.

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23

Yang, Hongyou, Jason Acker, Austin Chen, and Locksley McGann. "In Situ Assessment of Cell Viability." Cell Transplantation 7, no. 5 (1998): 443–51. http://dx.doi.org/10.1177/096368979800700503.

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Cryobiologlcal studies of tissues often require the simultaneous assessment of tissue structure and in situ cellular function. Localization of damage during cryopreservation occurs as a consequence of tissue structure and morphology and as a result of biophysical constraints imposed by diffusion and heat transfer. This study used five experimental model tissue systems: cells in suspension, cells attached to a substrate, a monolayer of cells attached to a substrate, porcine corneas, and intact porcine articular cartilage to examine the efficacy of assessing cell recovery using a novel fluoresce

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24

Cook, John A., and James B. Mitchell. "Viability measurements in mammalian cell systems." Analytical Biochemistry 179, no. 1 (1989): 1–7. http://dx.doi.org/10.1016/0003-2697(89)90191-7.

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25

Chae, Min Seok, and Heidi Schraft. "Cell viability of Listeria monocytogenes biofilms." Food Microbiology 18, no. 1 (2001): 103–12. http://dx.doi.org/10.1006/fmic.2000.0374.

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26

Šrobárová, Antonia, Jaime A Teixeira da Silva, Grigorij Kogan, Alberto Ritieni, and Antonello Santini. "Beauvericin Decreases Cell Viability of Wheat." Chemistry & Biodiversity 6, no. 8 (2009): 1208–15. http://dx.doi.org/10.1002/cbdv.200800158.

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27

Simon, TL, W. McDonough, and MK Warthen. "Red cell viability with infusion systems." Transfusion 34, no. 3 (1994): 278–79. http://dx.doi.org/10.1046/j.1537-2995.1994.34394196632.x.

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28

Moloney, Brian. "Improving cell viability through controlled freezing." Cell and Gene Therapy Insights 10, no. 01 (2024): 45. http://dx.doi.org/10.18609/cgti.2024.008.

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29

Blome-Eberwein, Sigrid, Caitlin Stoudt, Hamed Amani, Sakura Helm, and Kyle Shaak. "33 Real World Cell Viability in Cell Spray Suspension." Journal of Burn Care & Research 46, Supplement_1 (2025): S28. https://doi.org/10.1093/jbcr/iraf019.033.

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Abstract Introduction Autologous epithelial cell spray, prepared with a commercial kit, is now widely used in American Burn Centers in extensive second and third degree burns where donor skin may be scarce. However, the cell viability and yield of the autologous skin suspension has not been assessed in a real-world setting and there is limited data on patient age and other demographics that may influence the number of viable cells in the suspension. The purpose of this IRB approved study was to evaluate the cell viability of an autologous skin cell suspension in a variety of age groups and Fit

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30

Vasyliev, R. G. "CULTIVATION OF NEURAL CREST-DERIVED MULTIPOTENT STEM CELLS IN COLLAGEN AND FIBRIN HYDROGELS: EFFECTS ON CELL VIABILITY AND PROLIFERATION." Biotechnologia acta 7, no. 5 (2014): 50–54. http://dx.doi.org/10.15407/biotech7.05.050.

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31

Muhamed Ilyas, Aswiyaa. "Biocompatibility of Silicate Based Root Canal Sealers on Human Fibroblast Cells-In Vitro Study based on Cell Viability Assay." International Journal of Science and Research (IJSR) 12, no. 7 (2023): 1842–52. http://dx.doi.org/10.21275/sr23718010426.

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32

Akter, Saleha, Rama Addepalli, Michael E. Netzel, et al. "Antioxidant-Rich Extracts of Terminalia ferdinandiana Interfere with Estimation of Cell Viability." Antioxidants 8, no. 6 (2019): 191. http://dx.doi.org/10.3390/antiox8060191.

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The impact of plant extracts and phytochemicals on in vitro cell viability is usually assessed by employing cell viability assays dependent upon the activity of dehydrogenase enzymes. The CellTiter 96® AQueous One Solution Cell Proliferation Assay (CellTiter) was used to measure cell viability in response to antioxidant-rich extracts of Terminalia ferdinandiana fruits. Conflicting results were obtained from this assay whereby higher concentrations of extracts significantly increased cell viability compared to lower concentrations. Intrinsic reductive potential was observed in a cell-free syste

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33

Dewi, Syarifah, Mohamad Sadikin, Muchlis Ramli, and Septelia Inawati Wanandi. "HDAC2 and PCNA expression is correlated to decreasing of endoxifen sensitivity in human breast cancer stem cells ALDH+." Health Science Journal of Indonesia 10, no. 2 (2019): 77–81. http://dx.doi.org/10.22435/hsji.v12i2.2449.

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Latar belakang: Sel punca kanker payudara (breast cancer stem cells/BCSC) adalah subpopulasi sel kanker yang memiliki kemampuan menghasilkan tumor baru dan bersifat seperti sel punca. Penelitian kami sebelumnya menggunakan jaringan kanker payudara mengungkapkan bahwa ekspresi gen histone deacetylase 2 (HDAC2) dan proliferating cell nuclear antigen (PCNA) ditemukan perbedaan signifikan setelah terapi neoajuvan hormon dan kemoterapi. Penelitian ini bertujuan untuk menganalisis hubungan antara ekspresi HDAC2 dan PCNA dengan kelangsungan hidup sel punca kanker payudara dengan penanda aldehyde dehy

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34

Cui, Xiang-Shun, Yong-Nan Xu, Xing-Hui Shen, Li-Qun Zhang, Jia-Bao Zhang, and Nam-Hyung Kim. "Trichostatin A Modulates Apoptotic-Related Gene Expression and Improves Embryo Viability in Cloned Bovine Embryos." Cellular Reprogramming 13, no. 2 (2011): 179–89. http://dx.doi.org/10.1089/cell.2010.0060.

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35

Huang, Yongyang, Samir Patel, Mackenzie Pierce, Bo Lin, and Leo Chan. "Characterization and comparison of acridine orange/propidium iodide and acridine/DAPI viability detection methods for cell and gene therapy development." Journal of Immunology 210, no. 1_Supplement (2023): 249.05. http://dx.doi.org/10.4049/jimmunol.210.supp.249.05.

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Abstract Cell viability is one of the critical quality attributes (CQAs) for analyzing and characterizing cellular therapeutic products. The characterization of cell viability is essential to ensure quality, safety and efficacy during cell and gene therapy development. In this work, we characterized and compared two commonly used viability dual-staining methods, acridine orange/propidium iodide (AO/PI) and acridine orange/4′,6-diamidino-2-phenylindole (AO/DAPI) using the Cellaca MX high-throughput cell counter. In general, the AO/DAPI method provided higher viability results than AO/PI, with t

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36

Wang, Junxin, and Jesse V. Jokerst. "Stem Cell Imaging: Tools to Improve Cell Delivery and Viability." Stem Cells International 2016 (2016): 1–16. http://dx.doi.org/10.1155/2016/9240652.

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Stem cell therapy (SCT) has shown very promising preclinical results in a variety of regenerative medicine applications. Nevertheless, the complete utility of this technology remains unrealized. Imaging is a potent tool used in multiple stages of SCT and this review describes the role that imaging plays in cell harvest, cell purification, and cell implantation, as well as a discussion of how imaging can be used to assess outcome in SCT. We close with some perspective on potential growth in the field.

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37

Zeigler, Maxwell B., and Daniel T. Chiu. "Laser Selection Significantly Affects Cell Viability Following Single-Cell Nanosurgery." Photochemistry and Photobiology 85, no. 5 (2009): 1218–24. http://dx.doi.org/10.1111/j.1751-1097.2009.00581.x.

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38

Coombe, Deirdre R., Anne-Marie Nakhoul, Sandra M. Stevenson, Susanne E. Peroni, and Colin J. Sanderson. "Expressed luciferase viability assay (ELVA) for the measurement of cell growth and viability." Journal of Immunological Methods 215, no. 1-2 (1998): 145–50. http://dx.doi.org/10.1016/s0022-1759(98)00081-7.

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39

Li, A., M. Barabadi, G. Kusuma, D. James, and R. Lim. "Improving cell viability using counterflow centrifugation elutriation." Cytotherapy 23, no. 5 (2021): S180. http://dx.doi.org/10.1016/s1465324921005879.

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40

Jang, Eui Chan, Eun Woo Lee, Soo Yong Kang, and Ki Ser Kang. "Bone Cell Viability after Exposure to Air." Journal of the Korean Orthopaedic Association 32, no. 6 (1997): 1464. http://dx.doi.org/10.4055/jkoa.1997.32.6.1464.

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41

VanOosten, Sarah Kay, Esra Yuca, Banu Taktak Karaca, et al. "Biosilver nanoparticle interface offers improved cell viability." Surface Innovations 4, no. 3 (2016): 121–32. http://dx.doi.org/10.1680/jsuin.16.00010.

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42

Ma, Shuhe, Kosaku Murakami, Kazune Tanaka, et al. "Fatostatin ameliorates inflammation without affecting cell viability." FEBS Open Bio 12, no. 3 (2022): 594–604. http://dx.doi.org/10.1002/2211-5463.13364.

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43

Ramirez, Christina Nicole, Christophe Antczak, and Hakim Djaballah. "Cell viability assessment: toward content-rich platforms." Expert Opinion on Drug Discovery 5, no. 3 (2010): 223–33. http://dx.doi.org/10.1517/17460441003596685.

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44

TREBLE, NICHOLAS J., JOHN C. DORGAN, and JAMES A. GALLAGHER. "Maintenance of Cell Viability in Stored Bone." Spine 15, no. 8 (1990): 830–32. http://dx.doi.org/10.1097/00007632-199008000-00017.

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45

TREBLE, NICHOLAS J., JOHN C. DORGAN, and JAMES A. GALLAGHER. "Maintenance of Cell Viability in Stored Bone." Spine 15, no. 8 (1990): 830–32. http://dx.doi.org/10.1097/00007632-199008010-00017.

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46

Huselstein, C., N. de Isla, M. N. Kolopp-Sarda, H. Kerdjoudj, S. Muller, and J. F. Stoltz. "Influence of mechanical stress on cell viability." Biorheology: The Official Journal of the International Society of Biorheology 43, no. 3-4 (2006): 371–75. http://dx.doi.org/10.1177/0006355x2006043003004020.

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The cartilage is a hydrated connective tissue in joints that withstands and distributes mechanical forces. The chondrocytes utilize mechanical signals to regulate their metabolic activity through complex biological and biophysical interactions with the extracellular matrix (ECM). The aim of this work was to study the influence of mechanical stress on cells behavior cultured in 3D biosystems (alginate and alginate supplemented with hyaluronate). After mechanical stimulation, cell viability and cell death process were the main studied parameters. Our results indicated that viability and cell cyc

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47

Wagner, Nana-Maria, Caroline Van Aken, Antje Butschkau, et al. "Procalcitonin Impairs Endothelial Cell Function and Viability." Anesthesia & Analgesia 124, no. 3 (2017): 836–45. http://dx.doi.org/10.1213/ane.0000000000001574.

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48

Itle, Laura J., and Michael V. Pishko. "Multiphenotypic Whole-Cell Sensor for Viability Screening." Analytical Chemistry 77, no. 24 (2005): 7887–93. http://dx.doi.org/10.1021/ac051012b.

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49

Virga, Maria Carolina, Alejandra Aguzzi, Adriana de Leonardi, and Daniel Salica. "Cell Viability Assessment With Alendronate And Pamidronate." Journal of Clinical Densitometry 14, no. 2 (2011): 160. http://dx.doi.org/10.1016/j.jocd.2011.02.028.

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50

Henry-Stanley, Michelle J., and Carol L. Wells. "Viability and Versatility of the Yeast Cell." Microscopy Today 12, no. 3 (2004): 30–33. http://dx.doi.org/10.1017/s1551929500052135.

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Yeasts are single-celled eukaryotic microorganisms (generally about 5 to 10 microns in diameter) that divide by a budding process and are classified with the fungi. Yeast cells are ubiquitous in our environment and can be found on plants and in soil and water. Yeasts have considerable importance Ln industrial and agricultural settings,Saccharomyces cerevisiae(Figure 1) is also known as “bakers yeast” or “brewers yeast.” Specific strains of yeast are used to make pastries, bread, beer, ale, wine, distilled spirits, and industrial alcohol. In the paper industry,Candida utilisis used to break dow

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