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1

Völkl, H., M. Paulmichl, and F. Lang. "Cell Volume Regulation in Renal Cortical Cells." Kidney and Blood Pressure Research 11, no. 3-5 (1988): 158–73. http://dx.doi.org/10.1159/000173160.

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2

Macknight, Anthony D. C. "Principles of Cell Volume Regulation." Kidney and Blood Pressure Research 11, no. 3-5 (1988): 114–41. http://dx.doi.org/10.1159/000173158.

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3

Graf, J., P. Haddad, D. Haeussinger, and F. Lang. "Cell Volume Regulation in Liver." Kidney and Blood Pressure Research 11, no. 3-5 (1988): 202–20. http://dx.doi.org/10.1159/000173163.

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4

Deutsch, Carol, and Sherwin C. Lee. "Cell Volume Regulation in Lymphocytes." Kidney and Blood Pressure Research 11, no. 3-5 (1988): 260–76. http://dx.doi.org/10.1159/000173166.

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5

Lewis, Rebecca, Claire H. Feetham, and Richard Barrett-Jolley. "Cell Volume Regulation in Chondrocytes." Cellular Physiology and Biochemistry 28, no. 6 (2011): 1111–22. http://dx.doi.org/10.1159/000335847.

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6

Hoffmann, Else K. "Cell Swelling and Volume Regulation." Canadian Journal of Physiology and Pharmacology 70, S1 (1992): S310—S313. http://dx.doi.org/10.1139/y92-277.

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The extracellular space in the brain is typically 20% of the tissue volume and is reduced to at least half its size under conditions of neural insult. Whether there is a minimum size to the extracellular space was discussed. A general model for cell volume regulation was presented, followed by a discussion on how many of the generally involved mechanisms are identified in neural cells and (or) in astrocytes. There seems to be clear evidence suggesting that parallel K+ and Cl− channels mediate regulatory volume decrease in primary cultures of astrocytes, and a stretch-activated cation channel h
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7

Civan, M. M. "Overview of cell volume regulation." Experimental Eye Research 55 (September 1992): 126. http://dx.doi.org/10.1016/0014-4835(92)90655-c.

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8

Wang, Meng, Yaowei Yang, Lichun Han, Feng Xu, and Fei Li. "Cell mechanical microenvironment for cell volume regulation." Journal of Cellular Physiology 235, no. 5 (2019): 4070–81. http://dx.doi.org/10.1002/jcp.29341.

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9

Gómez-Angelats, Mireia, Carl D. Bortner, and John A. Cidlowski. "Cell volume regulation in immune cell apoptosis." Cell and Tissue Research 301, no. 1 (2000): 33–42. http://dx.doi.org/10.1007/s004410000216.

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10

Okada, Y. "Volume-sensitive chloride channels and cell volume regulation." Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 126 (July 2000): 111. http://dx.doi.org/10.1016/s1095-6433(00)80220-2.

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11

TAKEUCHI, Ayako, and Akinori NOMA. "Systems Biology of Cell Volume Regulation." Seibutsu Butsuri 50, no. 5 (2010): 248–51. http://dx.doi.org/10.2142/biophys.50.248.

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12

Pedersen, S. F., E. K. Hoffmann, and J. W. Mills. "The cytoskeleton and cell volume regulation." Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 130, no. 3 (2001): 385–99. http://dx.doi.org/10.1016/s1095-6433(01)00429-9.

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13

Mitchell, Claire H., Johannes C. Fleischhauer, W. Daniel Stamer, K. Peterson-Yantorno, and Mortimer M. Civan. "Human trabecular meshwork cell volume regulation." American Journal of Physiology-Cell Physiology 283, no. 1 (2002): C315—C326. http://dx.doi.org/10.1152/ajpcell.00544.2001.

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The volume of certain subpopulations of trabecular meshwork (TM) cells may modify outflow resistance of aqueous humor, thereby altering intraocular pressure. This study examines the contribution that Na+/H+, Cl−/HCO[Formula: see text]exchange, and K+-Cl− efflux mechanisms have on the volume of TM cells. Volume, Cl− currents, and intracellular Ca2+ activity of cultured human TM cells were studied with calcein fluorescence, whole cell patch clamping, and fura 2 fluorescence, respectively. At physiological bicarbonate concentration, the selective Na+/H+ antiport inhibitor dimethylamiloride reduce
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14

Dunkelberg, J. "Liver cell volume regulation: Size matters." Hepatology 33, no. 6 (2001): 1349–52. http://dx.doi.org/10.1053/jhep.2001.24750.

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15

Reuss, Luis. "Cell Volume Regulation in Nonrenal Epithelia." Kidney and Blood Pressure Research 11, no. 3-5 (1988): 187–201. http://dx.doi.org/10.1159/000173162.

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16

Mills, J. W. "The cytoskeleton and cell volume regulation." Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 126 (July 2000): 105. http://dx.doi.org/10.1016/s1095-6433(00)80207-x.

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17

Montrose-Rafizadeh, C., and W. B. Guggino. "Cell Volume Regulation in the Nephron." Annual Review of Physiology 52, no. 1 (1990): 761–72. http://dx.doi.org/10.1146/annurev.ph.52.030190.003553.

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18

Arrazola, A., R. Rota, P. Hannaert, A. Soler, and R. P. Garay. "Cell volume regulation in rat thymocytes." Journal of Physiology 465, no. 1 (1993): 403–14. http://dx.doi.org/10.1113/jphysiol.1993.sp019683.

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19

Gallagher, Patrick G. "Disorders of red cell volume regulation." Current Opinion in Hematology 20, no. 3 (2013): 201–7. http://dx.doi.org/10.1097/moh.0b013e32835f6870.

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20

Joerges, Jelena, Tobias Schulz, Jeannine Wegner, Udo Schumacher, and Peter Prehm. "Regulation of cell volume by glycosaminoglycans." Journal of Cellular Biochemistry 113, no. 1 (2011): 340–48. http://dx.doi.org/10.1002/jcb.23360.

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21

Linker, C., and T. H. Wilson. "Cell volume regulation in Mycoplasma gallisepticum." Journal of Bacteriology 163, no. 3 (1985): 1243–49. http://dx.doi.org/10.1128/jb.163.3.1243-1249.1985.

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22

McCarty, N. A., and R. G. O'Neil. "Calcium signaling in cell volume regulation." Physiological Reviews 72, no. 4 (1992): 1037–61. http://dx.doi.org/10.1152/physrev.1992.72.4.1037.

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It is evident from the present analysis that although a role for Ca2+ in controlling hypertonic cell volume regulation and RVI mechanisms has not been shown, Ca2+ plays a central role in activating and controlling hypotonic cell volume regulation and RVD mechanisms in most cells. However, this Ca2+ dependency is highly variable among cell types and tissues. Cells can be grouped into three general categories based on the relative dependency of RVD on Ca2+: 1) cells that are highly dependent on extracellular Ca2+ and the activation of Ca2+ influx, supposedly reflecting activation of Ca2+ channel
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23

Lambert, I. H., E. K. Hoffmann, and S. F. Pedersen. "Cell volume regulation: physiology and pathophysiology." Acta Physiologica 194, no. 4 (2008): 255–82. http://dx.doi.org/10.1111/j.1748-1716.2008.01910.x.

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24

Al-Habori, Molham. "Cell volume and ion transport regulation." International Journal of Biochemistry 26, no. 3 (1994): 319–34. http://dx.doi.org/10.1016/0020-711x(94)90052-3.

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25

Fitz, Greg. "Molecular mechanisms of cell volume regulation." Gastroenterology 107, no. 6 (1994): 1906–7. http://dx.doi.org/10.1016/0016-5085(94)90846-x.

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26

Law, R. O. "Regulation of mammalian brain cell volume." Journal of Experimental Zoology 268, no. 2 (1994): 90–96. http://dx.doi.org/10.1002/jez.1402680204.

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27

Perez Gonzalez, Nicolas, Jiaxiang Tao, Nash D. Rochman, et al. "Cell tension and mechanical regulation of cell volume." Molecular Biology of the Cell 29, no. 21 (2018): 0. http://dx.doi.org/10.1091/mbc.e18-04-0213.

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Animal cells use an unknown mechanism to control their growth and physical size. Here, using the fluorescence exclusion method, we measure cell volume for adherent cells on substrates of varying stiffness. We discover that the cell volume has a complex dependence on substrate stiffness and is positively correlated with the size of the cell adhesion to the substrate. From a mechanical force–balance condition that determines the geometry of the cell surface, we find that the observed cell volume variation can be predicted quantitatively from the distribution of active myosin through the cell cor
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28

Okada, Yasunobu, and Emi Maeno. "Apoptosis, cell volume regulation and volume-regulatory chloride channels." Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology 130, no. 3 (2001): 377–83. http://dx.doi.org/10.1016/s1095-6433(01)00424-x.

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29

Hoffmann, Else K., Ian H. Lambert, and Stine F. Pedersen. "Physiology of Cell Volume Regulation in Vertebrates." Physiological Reviews 89, no. 1 (2009): 193–277. http://dx.doi.org/10.1152/physrev.00037.2007.

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The ability to control cell volume is pivotal for cell function. Cell volume perturbation elicits a wide array of signaling events, leading to protective (e.g., cytoskeletal rearrangement) and adaptive (e.g., altered expression of osmolyte transporters and heat shock proteins) measures and, in most cases, activation of volume regulatory osmolyte transport. After acute swelling, cell volume is regulated by the process of regulatory volume decrease (RVD), which involves the activation of KCl cotransport and of channels mediating K+, Cl−, and taurine efflux. Conversely, after acute shrinkage, cel
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30

Spring, Kenneth R., and Mikael Larson. "Volume regulation byNecturus gallbladder." Journal of Membrane Biology 84, no. 2 (1985): 191. http://dx.doi.org/10.1007/bf01872217.

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31

Lang, Florian, Erich Gulbins, Ildiko Szabo, et al. "Cell volume and the regulation of apoptotic cell death." Journal of Molecular Recognition 17, no. 5 (2004): 473–80. http://dx.doi.org/10.1002/jmr.705.

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32

Perez-Gonzalez, Nicolas A., Nash D. Rochman, Kai Yao, et al. "YAP and TAZ regulate cell volume." Journal of Cell Biology 218, no. 10 (2019): 3472–88. http://dx.doi.org/10.1083/jcb.201902067.

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How mammalian cells regulate their physical size is currently poorly understood, in part due to the difficulty in accurately quantifying cell volume in a high-throughput manner. Here, using the fluorescence exclusion method, we demonstrate that the mechanosensitive transcriptional regulators YAP (Yes-associated protein) and TAZ (transcriptional coactivator with PDZ-binding motif) are regulators of single-cell volume. The role of YAP/TAZ in volume regulation must go beyond its influence on total cell cycle duration or cell shape to explain the observed changes in volume. Moreover, for our exper
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33

Cohen, David M. "SRC family kinases in cell volume regulation." American Journal of Physiology-Cell Physiology 288, no. 3 (2005): C483—C493. http://dx.doi.org/10.1152/ajpcell.00452.2004.

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SRC family kinases are a group of nine cytoplasmic protein tyrosine kinases essential for many cell functions. Some appear to be ubiquitously expressed, whereas others are highly tissue specific. The ability of members of the SRC family to influence ion transport has been recognized for several years. Mounting evidence suggests a broad role for SRC family kinases in the cell response to both hypertonic and hypotonic stress, and in the ensuing regulatory volume increase or decrease. In addition, members of this tyrosine kinase family participate in the mechanotransduction that accompanies cell
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34

Ballanyi, K., and P. Grafe. "Cell Volume Regulation in the Nervous System." Kidney and Blood Pressure Research 11, no. 3-5 (1988): 142–57. http://dx.doi.org/10.1159/000173159.

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35

McManus, M., and K. Strange. "BRAIN CELL VOLUME REGULATION AFTER HYPERTONIC CHALLENGE." Anesthesiology 77, Supplement (1992): A789. http://dx.doi.org/10.1097/00000542-199209001-00789.

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36

Lang, Florian. "Mechanisms and Significance of Cell Volume Regulation." Journal of the American College of Nutrition 26, sup5 (2007): 613S—623S. http://dx.doi.org/10.1080/07315724.2007.10719667.

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37

Chamberlin, M. E., and K. Strange. "Anisosmotic cell volume regulation: a comparative view." American Journal of Physiology-Cell Physiology 257, no. 2 (1989): C159—C173. http://dx.doi.org/10.1152/ajpcell.1989.257.2.c159.

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A variety of organisms and cell types spanning the five taxonomic kingdoms are exposed, either naturally or through experimental means, to osmotic stresses. A common physiological response to these challenges is maintenance of cell volume through changes in the concentration of intracellular inorganic and organic solutes, collectively termed osmolytes. Research on the mechanisms by which the concentration of these solutes is regulated has proceeded along several experimental lines. Extensive studies on osmotically activated ion transport pathways have been carried out in vertebrate cells and t
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38

Renfro, J. Larry. "Cell volume regulation: skating through the pathways." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 288, no. 4 (2005): R798. http://dx.doi.org/10.1152/ajpregu.00874.2004.

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39

Lang, M. A. "Correlation between osmoregulation and cell volume regulation." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 252, no. 4 (1987): R768—R773. http://dx.doi.org/10.1152/ajpregu.1987.252.4.r768.

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The euryhaline crab, Callinectes sapidus, behaves both as an osmoregulator when equilibrated in salines in the range of 800 mosM and below and an osmoconformer when equilibrated in salines above 800 mosM. There exists a close correlation between osmoregulation seen in the whole animal in vivo and cell volume regulation studied in vitro. Hyperregulation of the hemolymph osmotic pressure and cell volume regulation both occurred in salines at approximately 800 mosM and below. During long-term equilibration of the crabs to a wide range of saline environments, the total concentration of hemolymph a
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40

Compan, Vincent, Alberto Baroja-Mazo, Gloria López-Castejón, et al. "Cell Volume Regulation Modulates NLRP3 Inflammasome Activation." Immunity 37, no. 3 (2012): 487–500. http://dx.doi.org/10.1016/j.immuni.2012.06.013.

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41

Spring, Kenneth R., and Arthur W. Siebens. "Solute transport and epithelial cell volume regulation." Comparative Biochemistry and Physiology Part A: Physiology 90, no. 4 (1988): 557–60. http://dx.doi.org/10.1016/0300-9629(88)90667-6.

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42

Blase, Christopher, Daniel Becker, Sven Kappel, and Jürgen Bereiter-Hahn. "Microfilament dynamics during HaCaT cell volume regulation." European Journal of Cell Biology 88, no. 3 (2009): 131–39. http://dx.doi.org/10.1016/j.ejcb.2008.10.003.

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43

Mongin, Alexander A., and Sergei N. Orlov. "Mechanisms of cell volume regulation and possible nature of the cell volume sensor." Pathophysiology 8, no. 2 (2001): 77–88. http://dx.doi.org/10.1016/s0928-4680(01)00074-8.

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44

Rahimzadeh, Jason, and Susan Z. Hua. "Effect of Cytoskeleton on Cell Volume Regulation in Mdck Cells." Biophysical Journal 100, no. 3 (2011): 101a. http://dx.doi.org/10.1016/j.bpj.2010.12.761.

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45

Lang, Florian, Markus Ritter, Nikita Gamper, et al. "Cell Volume in the Regulation of Cell Proliferation and Apoptotic Cell Death." Cellular Physiology and Biochemistry 10, no. 5-6 (2000): 417–28. http://dx.doi.org/10.1159/000016367.

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46

Diaz, Roberto J., Michael Charnish, Jason Nobel, Michelle Batthish, Alina Hinek, and Gregory J. Wilson. "08 Preconditioning enhances cell volume regulation in cardiomyocytes." Journal of Molecular and Cellular Cardiology 34, no. 7 (2002): A34. http://dx.doi.org/10.1016/s0022-2828(02)90192-6.

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47

Assender, J. W., J. E. Chapman, and S. K. Hall. "MITOGEN ACTIVATED PROTEIN KINASE MEDIATED CELL VOLUME REGULATION." Biochemical Society Transactions 28, no. 5 (2000): A272. http://dx.doi.org/10.1042/bst028a272b.

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48

Diaz, Roberto J., Kelly Fernandes, Yuliya Lytvyn, et al. "Enhanced cell-volume regulation in cyclosporin A cardioprotection." Cardiovascular Research 98, no. 3 (2013): 411–19. http://dx.doi.org/10.1093/cvr/cvt056.

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49

Wine, Jeffrey J., and Douglas B. Luckie. "Cell-volume regulation: P-glycoprotein – a cautionary tale." Current Biology 6, no. 11 (1996): 1410–12. http://dx.doi.org/10.1016/s0960-9822(96)00744-0.

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50

Grinstein, S., and J. K. Foskett. "Ionic Mechanisms of Cell Volume Regulation in Leukocytes." Annual Review of Physiology 52, no. 1 (1990): 399–414. http://dx.doi.org/10.1146/annurev.ph.52.030190.002151.

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