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Journal articles on the topic 'Cellule TFH'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

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1

Gupta, Sudhir, Houfen Su, Sudhanshu Agrawal, Yesim Demirdag, Michelle Tran, and Sastry Gollapudi. "Adaptive Cellular Responses following SARS-CoV-2 Vaccination in Primary Antibody Deficiency Patients." Pathogens 13, no. 6 (2024): 514. http://dx.doi.org/10.3390/pathogens13060514.

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Since the start of the COVID-19 pandemic, in a short span of 3 years, vaccination against SARS-CoV-2 has resulted in the end of the pandemic. Patients with inborn errors of immunity (IEI) are at an increased risk for SARS-CoV-2 infection; however, serious illnesses and mortality, especially in primary antibody deficiencies (PADs), have been lower than expected and lower than other high-risk groups. This suggests that PAD patients may mount a reasonable effective response to the SARS-CoV-2 vaccine. Several studies have been published regarding antibody responses, with contradictory reports. The

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Watanabe, Masashi, Chiharu Fujihara, Chiang Y. Jeffrey, Sumeena Bhatia, and Richard J. Hodes. "Costimulatory pathways mediating T-dependent germinal center responses: distinct cellular requirements for CD40 and B7 costimulation." Journal of Immunology 196, no. 1_Supplement (2016): 55.25. http://dx.doi.org/10.4049/jimmunol.196.supp.55.25.

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Abstract T cell-dependent (TD) germinal center (GC) and antibody responses require coordinated interactions of T cells with B cells and antigen-presenting dendritic cells (DCs). Although B7 and CD40 costimulatory pathways are critical for these responses, a comprehensive analysis of cell type-specific pathways has been hindered by the absence of models for conditional expression of B7 or CD40. Here we report generation of conditional knockout mice for both B7 and CD40, and the use of these lines together with conditional MHC class II (MHCII) knockouts and bone marrow chimeric strategies, to an

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Cha, Junha, Da Hee Kim, Gamin Kim, et al. "Single-cell analysis reveals cellular and molecular factors counteracting HPV-positive oropharyngeal cancer immunotherapy outcomes." Journal for ImmunoTherapy of Cancer 12, no. 6 (2024): e008667. http://dx.doi.org/10.1136/jitc-2023-008667.

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BackgroundOropharyngeal squamous cell carcinoma (OPSCC) induced by human papillomavirus (HPV-positive) is associated with better clinical outcomes than HPV-negative OPSCC. However, the clinical benefits of immunotherapy in patients with HPV-positive OPSCC remain unclear.MethodsTo identify the cellular and molecular factors that limited the benefits associated with HPV in OPSCC immunotherapy, we performed single-cell RNA (n=20) and T-cell receptor sequencing (n=10) analyses of tonsil or base of tongue tumor biopsies prior to immunotherapy. Primary findings from our single-cell analysis were con

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Watanabe, Masashi, and Richard Hodes. "Cellular and molecular basis of Ag-specific and Ag-nonspecific T-dependent antibody responses in vivo (IRC8P.447)." Journal of Immunology 194, no. 1_Supplement (2015): 129.11. http://dx.doi.org/10.4049/jimmunol.194.supp.129.11.

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Abstract Although B7 is essential for T-dependent Ag-specific Ab production, little is known about cell type specific role of B7 for these responses. Utilizing B7cKO mice, the cell type specific roles of B7 costimulation for T-dependent GC and Ab responses were analyzed. Upon NP-OVA/Alum immunization, NP-specific IgG1 production was profoundly defective in mice lacking B7 expression on DC (DC-B7KO) but was intact in mice lacking B7 on B cells (BC-B7KO). Consistent with this, NP-binding GC B cells and Ag-specific CD4+ T cell expansion were not observed in DC-B7KO. Surprisingly, however, GC form

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Utama, Naufal Saputra, Rosy Hutami, and Raden Siti Nurlaela. "Chemical and Sensory Characteristics of Sugar-Free Lemon Flavored Ready to Drink Tea with Different Carboxymethyl Cellulose Concentrations." Jurnal Pangan dan Agroindustri 13, no. 2 (2025): 123–34. https://doi.org/10.21776/ub.jpa.2025.013.02.6.

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Abstract Ready to drink (RTD) beverages like lemon-flavored tea can be consumed without preparation. This study analyzed the effect of Carboxymethyl Cellulose (CMC) concentrations on sugar-free lemon tea's pH, dissolved solids, polyphenol, sensory attributes and hedonic ratings. A Completely Randomized Design (CRD) with one factor, namely the concentration of CMC used as the variable. The CMC concentration factor was divided into 5 levels: 0.10%, 0.15%, 0.20%, 0.25%, and 0.30%. The results of the study indicated that the concentration of CMC affected pH levels, hedonic taste testing, sensory t

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Norka, A. O., R. N. Kuznetsova, S. V. Kudryavtsev, S. N. Kovalenko, M. K. Serebriakova, and S. V. Vorobyev. "ESPECIALLY CELLULAR IMMUNITY IN PATIENTS WITH TRAUMATIC BRAIN INJURY OF DIFFERENT SEVERITY IN ACUTE PERIOD." Medical academic journal 19, no. 1S (2019): 96–98. http://dx.doi.org/10.17816/maj191s196-98.

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Currently, it is known that in response to brain damage a reaction from the immune system is triggered, but its role in the formation of clinical manifestations remains a little-studied problem to date. Using multicolor cytometric analysis, a study was conducted to determine the number of Th1-, Th2-, Tfh- and Th17-cells among CD45RA-negative CD3+CD4+ cells in a group of patients with mild TBI (M-TBI, n = 20) and with moderate to severe TBI (MS-TBI, n = 16) and a group of conditionally healthy donors (n = 30). The imbalance between Th2 cells and Th17 cells was found in patients with TBI in the

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Bengtsson, Karin Lövgren, Haifeng Song, Linda Stertman, et al. "Matrix-M adjuvant enhances antibody, cellular and protective immune responses of a Zaire Ebola/Makona virus glycoprotein (GP) nanoparticle vaccine in mice." Vaccine 34, no. 16 (2016): 1927–35. https://doi.org/10.5281/zenodo.14822462.

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(Uploaded by Plazi for the Bat Literature Project) Ebola virus (EBOV) causes severe hemorrhagic fever for which there is no approved treatment or preventive vaccine. Immunological correlates of protective immunity against EBOV disease are not well understood. However, non-human primate studies have associated protection of experimental vaccines with binding and neutralizing antibodies to the EBOV glycoprotein (GP) as well as EBOV GP-specific CD4+ and CD8+ T cells. In this report a full length, unmodified Zaire EBOV GP gene from the 2014 EBOV Makona strain (EBOV/Mak) was cloned into a baculovir

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McGarry, Andrew, Mika Leinonen, Karl Kieburtz, Michal Geva, C. Warren Olanow, and Michael Hayden. "Effects of Pridopidine on Functional Capacity in Early-Stage Participants from the PRIDE-HD Study." Journal of Huntington's Disease 9, no. 4 (2020): 371–80. http://dx.doi.org/10.3233/jhd-200440.

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Background: No pharmacological treatment has been demonstrated to provide a functional benefit for persons with Huntington’s disease (HD). Pridopidine is a sigma-1-receptor agonist shown to have beneficial effects in preclinical models of HD. Objective: To further explore the effect of pridopidine on Total Functional Capacity (TFC) in the recent double-blind, placebo-controlled PRIDE-HD study. Methods: We performed post-hoc analyses to evaluate the effect of pridopidine on TFC at 26 and 52 weeks. Participants were stratified according to baseline TFC score and analyzed using repeated measures

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Kumashie, Kingsley Gideon, Molly Gallagher, Leena Babiker, et al. "Defining the Cellular and Molecular Features of CD4 T Cell Reconstitution Post Allo-HCT." Blood 144, Supplement 1 (2024): 7368. https://doi.org/10.1182/blood-2024-207622.

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Introduction Immune reconstitution after allogeneic hematopoietic cell transplantation (allo-HCT) is required for protection from infection and response to vaccination. However, lymphocyte reconstitution can cause Graft versus Host Disease (GvHD), and conversely, GvHD can impact immune reconstitution. The longitudinal dynamics of the emerging adaptive immune cells and how they are remodelled in GvHD have not been fully explored. Method: To capture features of emerging immune systems that were consistent across transplant contexts, we performed deep immunophenotyping on a cohort of 10 adults wh

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Liu, Huaying, Zhiyong Peng, Yuanying Zeng та ін. "Novel Triple Cellular Therapy with Tandem CAR-T, UCB, and TCR αβ -Depleted Haploidentical HCT Completely Prevented Relapse in R/R Acute Leukemia". Blood 144, Supplement 1 (2024): 7208. https://doi.org/10.1182/blood-2024-202900.

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Background: Relapse post hematopoietic cell transplant (HCT) still remains a major challenge in patients with relapsed/refractory (R/R) leukemia. Chimeric antigen receptor modified T cell (CAR-T) reducing leukemia burden and unrelated cord blood (UCB) having better anti-tumor effect than adult lymphocytes have well been recognized. It has also been proven, meanwhile, that antileukemia capacity based on NK allo-reactivity is potent in TCRab-depleted haploidentical HCT (TDH) because of high dose of NK cell infusion and reduced use of anti-GVHD medicines. Thus, we hypothesized that integration of

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Coffman, Jonathan A. "Enteroviruses Activate Cellular Innate Immune Responses Prior to Adaptive Immunity and Tropism Contributes to Severe Viral Pathogenesis." Microorganisms 13, no. 4 (2025): 870. https://doi.org/10.3390/microorganisms13040870.

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Numerous innate immune mechanisms have been shown to be activated during viral infections, including pattern recognition receptors (PRRs) functioning outside and inside the cell along with other sensors promoting the production of interferon and other cytokines. Innate cells, including NK cells, NKT cells, γδ T cells, dendritic cells, macrophages, and even neutrophils, have been shown to respond to viral infections. Several innate humoral responses to viral infections have also been identified. Adaptive immunity includes common cell-mediated immunity (CMI) and humoral responses. Th1, Th2, and

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Yan, LYU, MATSUNAGA Yukiko та Toshiro OHASHI. "Measuring cellular traction force during EndMT process induced by TFG-β". Proceedings of the JSME Conference on Frontiers in Bioengineering 2020.31 (2020): 1A15. http://dx.doi.org/10.1299/jsmebiofro.2020.31.1a15.

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Kaji, Tomohiro, Akiko Ishige, Masaki Hikida, et al. "Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory." Journal of Experimental Medicine 209, no. 11 (2012): 2079–97. http://dx.doi.org/10.1084/jem.20120127.

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One component of memory in the antibody system is long-lived memory B cells selected for the expression of somatically mutated, high-affinity antibodies in the T cell–dependent germinal center (GC) reaction. A puzzling observation has been that the memory B cell compartment also contains cells expressing unmutated, low-affinity antibodies. Using conditional Bcl6 ablation, we demonstrate that these cells are generated through proliferative expansion early after immunization in a T cell–dependent but GC-independent manner. They soon become resting and long-lived and display a novel distinct gene

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Busch, Maike, and Nicole Dünker. "Trefoil factor family peptides – friends or foes?" Biomolecular Concepts 6, no. 5-6 (2015): 343–59. http://dx.doi.org/10.1515/bmc-2015-0020.

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AbstractTrefoil factor family (TFF) peptides are a group of molecules bearing a characteristic three-loop trefoil domain. They are mainly secreted in mucous epithelia together with mucins but are also synthesized in the nervous system. For many years, TFF peptides were only known for their wound healing and protective function, e.g. in epithelial protection and restitution. However, experimental evidence has emerged supporting a pivotal role of TFF peptides in oncogenic transformation, tumorigenesis and metastasis. Deregulated expression of TFF peptides at the gene and protein level is obvious

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Aleman, Adolfo, Morgan Van Kesteren, Ariel Kogan Zajdman, et al. "Cellular Mechanisms Associated with Suboptimal Immune Responses to Sars-Cov-2 Bivalent Booster Vaccination in Patients with Multiple Myeloma." Blood 142, Supplement 1 (2023): 1984. http://dx.doi.org/10.1182/blood-2023-187260.

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Background: In response to the ever-evolving challenges posed by the antigenically diverse Omicron variants, the deployment of bivalent mRNA booster vaccines encompassing both the ancestral (WA1) and Omicron BA.5 spike components was initiated in fall of 2022. The real-world impact of these bivalent vaccines is largely unknown in patients with Multiple Myeloma (MM). We characterize the humoral and cellular immune responses in patients with MM before and after receiving the bivalent booster implementing cutting edge methodologies to identify patterns associated with continuing vulnerability in

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Sathe, Anuja, Carlos Ayala, Xiangqi Bai, et al. "Abstract 4121: Heterogenous cellular responses to GITR and TIGIT immunotherapy in the human gastrointestinal tumor microenvironment." Cancer Research 83, no. 7_Supplement (2023): 4121. http://dx.doi.org/10.1158/1538-7445.am2023-4121.

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Abstract Many new immunotherapy agents fail in clinical trials. Major gaps remain in our understanding of their precise mechanism of action, with findings from preclinical studies that do not translate into the clinic. We identified the cellular and molecular responses to co-stimulatory GITR and co-inhibitory TIGIT immunotherapy by using an experimental approach that overcomes these challenges. We investigated these responses in a patient-derived ex vivo system that maintains the original tumor microenvironment (TME) in its near-native state. Using single-cell RNA sequencing (scRNA-seq) and pa

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Heng, Jeffrey Lim Seng, and Halizah Hamzah. "Effects of different parameters on cellulase production by Trichoderma harzianum TF2 using solid‐state fermentation (SSF)." Indonesian Journal of Biotechnology 27, no. 2 (2022): 80. http://dx.doi.org/10.22146/ijbiotech.66549.

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Solid‐state fermentation is one of the easiest and cheapest methods for producing microbial bioactive com‐ pounds. Trichoderma harzianum has long been recognised as one of the potential fungi for this purpose. Trichoderma sp. were isolated from banana rhizosphere using the soil dilution method and later screened for their ability to produce cellulases using filter paper activity (FPase) and the carboxylmethyl cellulase (CMCase) test. Trichoderma sp. were also subjected to one factor change at a time to determine the effects of different parameters on cellulase production. It was observed that

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Gött, Peter, Ezzal-din Al-Azzeh, Veronika Dossinger, et al. "Regulation of TFF gene expression and modulation of the immune response by TFF (trefoil) peptides." Regulatory Peptides 94, no. 1-3 (2000): 62. http://dx.doi.org/10.1016/s0167-0115(00)80124-x.

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Siu, Elaine Hon-Lam, Anthony Wing-Hung Chan, Charing Ching-Ning Chong, Stephen Lam Chan, Kwok-Wai Lo, and Siu Tim Cheung. "Treatment of advanced hepatocellular carcinoma: immunotherapy from checkpoint blockade to potential of cellular treatment." Translational Gastroenterology and Hepatology 3 (November 2018): 89. http://dx.doi.org/10.21037/tgh.2018.10.16.

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Buckley, Paul R., Julie Chan, Cynthia Bishop, et al. "Highly Heterogeneous Cellular Composition and Neighborhood Architecture within the Follicular Lymphoma Tumor Microenvironment." Blood 144, Supplement 1 (2024): 4382. https://doi.org/10.1182/blood-2024-209877.

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The variable clinical course and response to treatment of Follicular Lymphoma (FL) is strongly influenced by its tumor microenvironment (TME). Indeed, cellular interactions dictate pro- and anti-tumor processes within the TME, although these mechanisms remain incompletely understood. Multiple bulk and single-cell studies have shed light on the TME with prognostic implications. For example, a macrophage gene signature as well as a ‘T cell depleted’ milieu have been associated with inferior clinical outcomes. Imaging Mass Cytometry (IMC) permits the multiplexed assessment of over 40 markers conc

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Yokose, Jun, William D. Marks, Naoki Yamamoto, Sachie K. Ogawa, and Takashi Kitamura. "Entorhinal cortical Island cells regulate temporal association learning with long trace period." Learning & Memory 28, no. 9 (2021): 319–28. http://dx.doi.org/10.1101/lm.052589.120.

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Temporal association learning (TAL) allows for the linkage of distinct, nonsynchronous events across a period of time. This function is driven by neural interactions in the entorhinal cortical–hippocampal network, especially the neural input from the pyramidal cells in layer III of medial entorhinal cortex (MECIII) to hippocampal CA1 is crucial for TAL. Successful TAL depends on the strength of event stimuli and the duration of the temporal gap between events. Whereas it has been demonstrated that the neural input from pyramidal cells in layer II of MEC, referred to as Island cells, to inhibit

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Deenick, Elissa, Anthony Lau, Tina Nguyen, Julia Bier, Robert Brink та Stuart Tangye. "Analysing the cellular mechanisms underlying activated PI3K δ Syndrome (APDS) reveals differences between APDS1 and APDS2". Journal of Immunology 208, № 1_Supplement (2022): 159.15. http://dx.doi.org/10.4049/jimmunol.208.supp.159.15.

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Abstract APDS is a primary immunodeficiency condition caused by heterozygous gain-of-function mutations in PIK3CD (APDS1), which encodes the leukocyte-restricted p110-δ catalytic subunit of phosphoinositide 3-kinase (PI3K) or heterozygous loss-of-function mutations in PIK3R1 (APDS2), which encodes the regulatory subunit of PI3K. PI3K is activated downstream of many receptors expressed by lymphocytes and plays important roles in their activation and differentiation. The increased PI3K activity in cells from APDS patients leads to multiple immune manifestations including lymphoproliferation, res

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Emami, Shahin, Sylvie Rodrigues, Christelle M. Rodrigue, et al. "Trefoil factor family (TFF) peptides and cancer progression." Peptides 25, no. 5 (2004): 885–98. http://dx.doi.org/10.1016/j.peptides.2003.10.019.

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Tungmunnithum, Duangjai, Samantha Drouet, Jose Manuel Lorenzo, and Christophe Hano. "Effect of Traditional Cooking and In Vitro Gastrointestinal Digestion of the Ten Most Consumed Beans from the Fabaceae Family in Thailand on Their Phytochemicals, Antioxidant and Anti-Diabetic Potentials." Plants 11, no. 1 (2021): 67. http://dx.doi.org/10.3390/plants11010067.

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The edible beans in Fabaceae have been used for foods and medicines since the ancient time, and being used more and more. It is also appeared as a major ingredient in dairy cooking menu in many regions including Thailand, a rich biodiversity country. Many studies reported on health benefits of their flavonoids, but there is no report on the effect of cooking on phytochemical profile and pharmacological potentials. Thus, this present study aims to complete this knowledge, with the 10 most consumed Fabaceae beans in Thailand, by determining the impact of traditional cooking and gastrointestinal

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Tarte, Karin, Céline Pangault, John de Vos, et al. "Gene Expression Profiling of Highly Purified Malignant and Non-Malignant Cells: Characterization of the Tumor-Microenvironment Cellular Synapse in De Novo Follicular Lymphoma (FL)." Blood 110, no. 11 (2007): 355. http://dx.doi.org/10.1182/blood.v110.11.355.355.

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Abstract Genetic and functional studies have demonstrated that FL cells retain the major features of normal germinal center (GC)-derived B cells, in particular the dependency on an active crosstalk with their specialized microenvironment. In agreement, microarray analyses have recently revealed that FL patient outcome is primarily predicted by molecular characteristics of tumor-infiltrating immune cells instead of tumor cells. However, our knowledge of the crucial interactions between malignant and non-malignant cells in FL remains limited by the use of whole biopsy specimen to perform gene ex

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Steven, P., G. Schäfer, B. Nölle, M. Hinz, W. Hoffmann, and F. Paulsen. "Distribution of TFF peptides in corneal disease and pterygium." Peptides 25, no. 5 (2004): 819–25. http://dx.doi.org/10.1016/j.peptides.2004.01.023.

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Paulsen, Friedrich P., Ulrich Schaudig, Alexander Fabian, Dirk Ehrich, and Saadettin Sel. "TFF peptides and mucins are major components of dacryoliths." Graefe's Archive for Clinical and Experimental Ophthalmology 244, no. 9 (2006): 1160–70. http://dx.doi.org/10.1007/s00417-005-0167-4.

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Arai, Takahiro, Hiroshi Murata, Masato Matsuura, Tomohiko Usui, and Ryo Asaoka. "The association between ocular surface measurements with visual field reliability indices and gaze tracking results in preperimetric glaucoma." British Journal of Ophthalmology 102, no. 4 (2017): 525–30. http://dx.doi.org/10.1136/bjophthalmol-2017-310309.

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Background/aimsTo investigate the relationship between gaze tracking (GT) results and ocular surface condition in glaucoma.MethodThe Humphrey 24–2 visual field (VF) was measured in 34 eyes of 30 patients with open-angle glaucoma without VF damage. Tear break-up time, Schirmer’s test, tear meniscus volume (TMV) and presence of superficial punctate keratopathy (SPK) were also measured in order to describe the condition of the ocular surface. Various GT parameters were calculated: the average frequency of eye movements per stimulus between 1° and 2° (move1-2), the average frequency of eye movemen

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Bourgne, Céline, Mahchid Bamdad, Alexandre Janel, et al. "Flow Cytometry Detection of Intra-Cellular Tyrosine Kinase Inhibitors (TKI) Showed Variable Uptake in CML CD34+ Cells." Blood 118, no. 21 (2011): 2747. http://dx.doi.org/10.1182/blood.v118.21.2747.2747.

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Abstract Abstract 2747 Introduction Despite the major benefit of TKI in the treatment of Chronic Myeloid Leukemia (CML), patient response is heterogeneous and it is generally accepted that residual disease and relapse are due to persistent CML cells, considered as leukemic stem cells. Their resistance has been related to lower TKI uptake. The amount of drug penetrating the targeted cells is most likely a major parameter of targeted therapy efficacy since it is essential that the therapeutic molecule be as close as possible to the target molecule. We developed a flow cytometry technique to anal

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Duvignaud, Jean-Baptiste, Denis Leclerc, and Stéphane M. Gagné. "Structure and dynamics changes induced by 2,2,2-trifluoro-ethanol (TFE) on the N-terminal half of hepatitis C virus core proteinThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting — Protein Folding: Principles and Diseases” and has undergone the Journal's usual peer review process." Biochemistry and Cell Biology 88, no. 2 (2010): 315–23. http://dx.doi.org/10.1139/o09-155.

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The Core protein of hepatitis C virus is involved in several interactions other than the encapsidation of viral RNA. We recently proposed that this is related to the fact that the N-terminal half of this protein (C82) is an intrinsically unstructured protein (IUP) domain. IUP domains can adopt a secondary structure when they are interacting with another molecule, such as a nucleic acid or a protein. It is also possible to mimic these conditions by modifying the environment of the protein. We investigated the propensity of this protein to fold as a function of salt concentration, detergent, pH,

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Grossman, Leah, Adolfo Aleman, Morgan van Kesteren, et al. "Monovalent XBB1.5 Vaccination Augments Humoral and Cellular Immunity to Novel Sars-Cov-2 Variants in Immunocompromised Patients with Multiple Myeloma." Blood 144, Supplement 1 (2024): 4691. https://doi.org/10.1182/blood-2024-203556.

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Background: Highly transmissible SARS-CoV-2 variants of concern such as Omicron XBB1.5 are of concern for patients that are immunocompromised. Patients with Multiple Myeloma (MM) remain particularly vulnerable due to therapies that deplete the machinery necessary for efficient humoral and cellular responses. MM patients continue to have an increased risk of severe COVID-19 manifestations, highlighting the necessity for continued evaluation of monovalent mRNA vaccine efficacy on adaptive immune activation in this population. Here, we assess the impact of the first monovalent Omicron XBB 1.5 vac

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Christine, Rivat, Rodrigues Sylvie, Bruyneel Erik, et al. "Implication of STAT3 Signaling in Human Colonic Cancer Cells during Intestinal Trefoil Factor 3 (TFF3) – and Vascular Endothelial Growth Factor–Mediated Cellular Invasion and Tumor Growth." Cancer Research 65, no. 1 (2005): 195–202. http://dx.doi.org/10.1158/0008-5472.195.65.1.

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Abstract Signal transducer and activator of transcription (STAT) 3 is overexpressed or activated in most types of human tumors and has been classified as an oncogene. In the present study, we investigated the contribution of the STAT3s to the proinvasive activity of trefoil factors (TFF) and vascular endothelial growth factor (VEGF) in human colorectal cancer cells HCT8/S11 expressing VEGF receptors. Both intestinal trefoil peptide (TFF3) and VEGF, but not pS2 (TFF1), activate STAT3 signaling through Tyr705 phosphorylation of both STAT3α and STAT3β isoforms. Blockade of STAT3 signaling by STAT

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De leval, L., D. Rickman, C. Thielen, et al. "Le profil d’expression génique des lymphomes T angio-immunoblastiques diffè de celui des lymphomes T périphériques sans spécificité et présente des analogies avec celui des cellules T Helper folliculaires(TFH)." Annales de Pathologie 26 (November 2006): 110. http://dx.doi.org/10.1016/s0242-6498(06)70781-7.

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Kutta, Hannes, Philipp Steven, Deike Varoga, and Friedrich P. Paulsen. "TFF peptides in the human false vocal folds of the larynx." Peptides 25, no. 5 (2004): 811–18. http://dx.doi.org/10.1016/j.peptides.2003.10.018.

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Nicolau, Stefan, and Teerin Liewluck. "TFG : At the crossroads of motor neuron disease and myopathy." Muscle & Nerve 60, no. 6 (2019): 645–47. http://dx.doi.org/10.1002/mus.26692.

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Kazantseva, Jekaterina, Kairit Tints, Toomas Neuman, and Kaia Palm. "TAF4 Controls Differentiation of Human Neural Progenitor Cells Through hTAF4-TAFH Activity." Journal of Molecular Neuroscience 55, no. 1 (2014): 160–66. http://dx.doi.org/10.1007/s12031-014-0295-6.

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37

Del Pino, Isabel, Chiara Tocco, Elia Magrinelli, et al. "COUP-TFI/Nr2f1 Orchestrates Intrinsic Neuronal Activity during Development of the Somatosensory Cortex." Cerebral Cortex 30, no. 11 (2020): 5667–85. http://dx.doi.org/10.1093/cercor/bhaa137.

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Abstract The formation of functional cortical maps in the cerebral cortex results from a timely regulated interaction between intrinsic genetic mechanisms and electrical activity. To understand how transcriptional regulation influences network activity and neuronal excitability within the neocortex, we used mice deficient for Nr2f1 (also known as COUP-TFI), a key determinant of primary somatosensory (S1) area specification during development. We found that the cortical loss of Nr2f1 impacts on spontaneous network activity and synchronization of S1 cortex at perinatal stages. In addition, we ob

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Shabir, Shabnam, Sumaira Yousuf, Sandeep Kumar Singh, Emanuel Vamanu, and Mahendra P. Singh. "Ethnopharmacological Effects of Urtica dioica, Matricaria chamomilla, and Murraya koenigii on Rotenone-Exposed D. melanogaster: An Attenuation of Cellular, Biochemical, and Organismal Markers." Antioxidants 11, no. 8 (2022): 1623. http://dx.doi.org/10.3390/antiox11081623.

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Natural antioxidants derived from plants have been proven to have significant inhibitory effects on the free radicals of living organisms during actively metabolization. Excessive production of free radicals increases the risk of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and motor sclerosis. This study aimed to compare the ethnopharmacological effects of Urtica dioica (UD), Matricaria chamomilla (MC), and Murraya koenigii (MK) on the amelioration of rotenone-induced toxicity in wild-type Drosophila melanogaster (Oregon R+) at biochemical, cellular, and behav

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Rappaport, Jay. "In fond remembrance and tribute to Dr. Kuan-Teh Jeang, M.D., Ph.D." Journal of NeuroVirology 19, no. 2 (2013): 117–18. http://dx.doi.org/10.1007/s13365-013-0157-y.

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Hoffmann, Werner. "Trefoil factor family (TFF) peptides: regulators of mucosal regeneration and repair, and more." Peptides 25, no. 5 (2004): 727–30. http://dx.doi.org/10.1016/j.peptides.2004.03.019.

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Evmorfiadis, Ilias, Paraskevi Boura, Aurélie Rousseau, et al. "Differential Influence of Lung Cancer Stage, Time from Diagnosis and Chemotherapy on Plasma and Cellular Biomarkers of Hypercoagulability. the Roadmap Study." Blood 124, no. 21 (2014): 4253. http://dx.doi.org/10.1182/blood.v124.21.4253.4253.

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Abstract Introduction. In patients with lung adenocarcinoma, metastasis, advanced stage and chemotherapy (CTx) are factors which increase the risk of venous thromboembolism (VTE). However, routine pharmacological thromboprophylaxis is not recommended but individualized risk assessment for VTE is encouraged. The incorporation of hypercoagulability biomarkers (HB) into the risk assessment models (RAM) could improve their sensitivity to identify patients eligible for thromboprophylaxis. To this aim we conducted an observational prospective study to investigate the variability of HB associated wit

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James, N. J., C. Ettelaie, and K. R. Bruckdorfer. "Inhibition of tissue factor activity reduces the density of cellular network formation in an in vitro model of angiogenesis." Biochemical Society Transactions 30, no. 2 (2002): 217–21. http://dx.doi.org/10.1042/bst0300217.

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Tissue factor (TF) is a transmembrane glycoprotein that was originally recognized for its ability to initiate the extrinsic pathway of coagulation. More recently, additional functions of TF in cellular signalling have emerged, notably the role of TF in vasculogenesis and angiogenesis. We have described previously the ability of a peptide derived from the apolipoprotein B100 (apoB100) moiety of low-density lipoproteins (KRAD14) to inhibit the procoagulant function of TF. In this study, we demonstrate the ability of the KRAD14 peptide to attenuate the density of cellular network structures of T2

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Tomi-Andrino, Claudio, Rupert Norman, Thomas Millat, et al. "Physicochemical and metabolic constraints for thermodynamics-based stoichiometric modelling under mesophilic growth conditions." PLOS Computational Biology 17, no. 1 (2021): e1007694. http://dx.doi.org/10.1371/journal.pcbi.1007694.

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Metabolic engineering in the post-genomic era is characterised by the development of new methods for metabolomics and fluxomics, supported by the integration of genetic engineering tools and mathematical modelling. Particularly, constraint-based stoichiometric models have been widely studied: (i) flux balance analysis (FBA) (in silico), and (ii) metabolic flux analysis (MFA) (in vivo). Recent studies have enabled the incorporation of thermodynamics and metabolomics data to improve the predictive capabilities of these approaches. However, an in-depth comparison and evaluation of these methods i

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Wagner, Andrea, Anja Doerks, Mordechai Aboud, et al. "Induction of Cellular Genes Is Mediated by the Bel1 Transactivator in Foamy Virus-Infected Human Cells." Journal of Virology 74, no. 10 (2000): 4441–47. http://dx.doi.org/10.1128/jvi.74.10.4441-4447.2000.

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ABSTRACT To gain insight into human foamy virus (HFV; also called spumaretrovirus)-induced alterations of cellular genes, the expression profiles of defined genes in HFV-infected primary human cells were analyzed by cDNA array assays. Several distinct cellular genes activated by HFV infection were identified; the identities of the cellular genes were confirmed by RNA blot analyses. Compared with mock-infected controls, the concentrations of cellular Kip2, Egr-1, COUP-TF1, insulin-like growth factor II (IGF-II), and EphB3 mRNAs were significantly increased in HFV-infected cells and showed a gen

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Sangaiah, Arun Kumar, Samira Rezaei, Amir Javadpour, Farimasadat Miri, Weizhe Zhang, and Desheng Wang. "Automatic Fault Detection and Diagnosis in Cellular Networks and Beyond 5G: Intelligent Network Management." Algorithms 15, no. 11 (2022): 432. http://dx.doi.org/10.3390/a15110432.

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Handling faults in a running cellular network can impair the performance and dissatisfy the end users. It is important to design an automatic self-healing procedure to not only detect the active faults, but also to diagnosis them automatically. Although fault detection has been well studied in the literature, fewer studies have targeted the more complicated task of diagnosing. Our presented method aims to tackle fault detection and diagnosis using two sets of data collected by the network: performance support system data and drive test data. Although performance support system data is collecte

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Otto, William R., Jagdish Rao, Carol Upton, Nasser Hajibagheri, and Nicholas A. Wright. "Interactions of TFF peptides with nuclei-enigmatic effects charged with or without meaning?" Regulatory Peptides 94, no. 1-3 (2000): 36. http://dx.doi.org/10.1016/s0167-0115(00)80073-7.

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Khan, Habiba, Tariq Khan, Nisar Ahmad, et al. "Chemical Elicitors-Induced Variation in Cellular Biomass, Biosynthesis of Secondary Cell Products, and Antioxidant System in Callus Cultures of Fagonia indica." Molecules 26, no. 21 (2021): 6340. http://dx.doi.org/10.3390/molecules26216340.

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Fagonia indica is a rich source of pharmacologically active compounds. The variation in the metabolites of interest is one of the major issues in wild plants due to different environmental factors. The addition of chemical elicitors is one of the effective strategies to trigger the biosynthetic pathways for the release of a higher quantity of bioactive compounds. Therefore, this study was designed to investigate the effects of chemical elicitors, aluminum chloride (AlCl3) and cadmium chloride (CdCl2), on the biosynthesis of secondary metabolites, biomass, and the antioxidant system in callus c

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Giraud, Andrew S., Prue M. Pereira, Lars Thim, Lorraine M. Parker, and Louise M. Judd. "TFF-2 inhibits iNOS/NO in monocytes, and nitrated protein in healing colon after colitis." Peptides 25, no. 5 (2004): 803–9. http://dx.doi.org/10.1016/j.peptides.2004.01.019.

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Hinz, Margitta, Herbert Schwegler, Caroline E. Chwieralski, et al. "Trefoil factor family (TFF) expression in the mouse brain and pituitary: changes in the developing cerebellum." Peptides 25, no. 5 (2004): 827–32. http://dx.doi.org/10.1016/j.peptides.2004.01.020.

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Torres, Felipe Vasconcelos, Fernanda Hansen, and Lucas Doridio Locks-Coelho. "Increase of extracellular glutamate concentration increases its oxidation and diminishes glucose oxidation in isolated mouse hippocampus: Reversible by TFB-TBOA." Journal of Neuroscience Research 91, no. 8 (2013): 1059–65. http://dx.doi.org/10.1002/jnr.23187.

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