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Dissertations / Theses on the topic 'Censored failure time outcome'

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1

ROTA, MATTEO. "Cut-pont finding methods for continuous biomarkers." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2013. http://hdl.handle.net/10281/40114.

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My PhD dissertation deals with statistical methods for cut-point finding for continuous biomarkers. Categorization is often needed for clinical decision making when dealing with diagnostic (or prognostic) biomarkers and a dichotomous or censored failure time outcome. This allows the definition of two or more prognostic risk groups, or also patient’s stratifications for inclusion in randomized clinical trials (RCTs). We investigate the following cut-point finding methods: minimum P-value, Youden index, concordance probability and point closest to-(0,1) corner in the ROC plane. We compare them
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2

Gorelick, Jeremy Sun Jianguo. "Nonparametric analysis of interval-censored failure time data." Diss., Columbia, Mo. : University of Missouri--Columbia, 2009. http://hdl.handle.net/10355/7009.

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Title from PDF of title page (University of Missouri--Columbia, viewed on Feb 26, 2010). The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file. Dissertation advisor: Dr. (Tony) Jianguo Sun. Includes bibliographical references.
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3

Wang, Lianming. "Statistical analysis of multivariate interval-censored failure time data." Diss., Columbia, Mo. : University of Missouri-Columbia, 2006. http://hdl.handle.net/10355/4375.

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Thesis (Ph.D.)--University of Missouri-Columbia, 2006.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file viewed on (May 2, 2007) Vita. Includes bibliographical references.
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4

Cai, Jianwen. "Generalized estimating equations for censored multivariate failure time data /." Thesis, Connect to this title online; UW restricted, 1992. http://hdl.handle.net/1773/9581.

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5

Chen, Man-Hua. "Statistical analysis of multivariate interval-censored failure time data." Diss., Columbia, Mo. : University of Missouri-Columbia, 2007. http://hdl.handle.net/10355/4776.

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Thesis (Ph.D.)--University of Missouri-Columbia, 2007.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on March 6, 2009) Includes bibliographical references.
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6

Zhao, Qiang. "Nonparametric treatment comparisons for interval-censored failure time data /." free to MU campus, to others for purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p3144474.

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7

Zhu, Chao. "Nonparametric and semiparametric methods for interval-censored failure time data." Diss., Columbia, Mo. : University of Missouri-Columbia, 2006. http://hdl.handle.net/10355/4415.

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Thesis (Ph.D.)--University of Missouri-Columbia, 2006.<br>The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file viewed on (May 2, 2007) Vita. Includes bibliographical references.
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8

Wong, Kin-yau, and 黃堅祐. "Analysis of interval-censored failure time data with long-term survivors." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48199473.

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Failure time data analysis, or survival analysis, is involved in various research fields, such as medicine and public health. One basic assumption in standard survival analysis is that every individual in the study population will eventually experience the event of interest. However, this assumption is usually violated in practice, for example when the variable of interest is the time to relapse of a curable disease resulting in the existence of long-term survivors. Also, presence of unobservable risk factors in the group of susceptible individuals may introduce heterogeneity to the po
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9

Bouadoumou, Maxime K. "Jackknife Empirical Likelihood for the Accelerated Failure Time Model with Censored Data." Digital Archive @ GSU, 2011. http://digitalarchive.gsu.edu/math_theses/112.

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Kendall and Gehan estimating functions are used to estimate the regression parameter in accelerated failure time (AFT) model with censored observations. The accelerated failure time model is the preferred survival analysis method because it maintains a consistent association between the covariate and the survival time. The jackknife empirical likelihood method is used because it overcomes computation difficulty by circumventing the construction of the nonlinear constraint. Jackknife empirical likelihood turns the statistic of interest into a sample mean based on jackknife pseudo-values. U-stat
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10

Goodall, R. L. "Analysis of interval-censored failure time data with application to studies of HIV infection." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1446247/.

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In clinical trials and cohort studies the event of interest is often not observable, and is known only to have occurred between the visit when the event was first observed and the previous visit such data are called interval-censored. This thesis develops three pieces of research that build upon published methods for interval-censored data. Novel methods are developed which can be applied via self-written macros in the standard packages, with the aim of increasing the use of appropriate methods in applied medical research. The non-parametric maximum likelihood estimator 1,2 (NPMLE) is the most
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11

Lim, Hee-Jeong. "Statistical analysis of interval-censored and truncated survival data /." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3025635.

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12

Shinohara, Russell. "Estimation of survival of left truncated and right censored data under increasing hazard." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=100210.

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When subjects are recruited through a cross-sectional survey they have already experienced the initiation of the event of interest, say the onset of a disease. This method of recruitment results in the fact that subjects with longer duration of the disease have a higher chance of being selected. It follows that censoring in such a case is not non-informative. The application of standard techniques for right-censored data thus introduces a bias to the analysis; this is referred to as length-bias. This paper examines the case where the subjects are assumed to enter the study at a uniform rate, a
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13

Colomay, Harold K. (Harold Kenney). "A survey of a class of nonparametric two-sample tests for right censored failure time data /." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=56645.

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This thesis takes an in-depth focus at a specific class of nonparametric two-sample procedures for right censored failure time data-standardized weighted log-rank (SWL) statistics. This family of tests comprises the very famous Gehan, Efron, and log-rank procedures. The first two of these reduce to the Wilcoxon test with censoring absent, while the third one is a censored data generalization of the Savage test. Two particular topics of interest to us are (1) the generation of SWL statistics as score tests within the context of some popular regression models, and (2) asymptotic and small-sample
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14

Cheung, Tak-lun Alan, and 張德麟. "Modelling multivariate interval-censored and left-truncated survival data using proportional hazards model." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B29536637.

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15

Lu, Yinghua. "Empirical Likelihood Inference for the Accelerated Failure Time Model via Kendall Estimating Equation." Digital Archive @ GSU, 2010. http://digitalarchive.gsu.edu/math_theses/76.

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In this thesis, we study two methods for inference of parameters in the accelerated failure time model with right censoring data. One is the Wald-type method, which involves parameter estimation. The other one is empirical likelihood method, which is based on the asymptotic distribution of likelihood ratio. We employ a monotone censored data version of Kendall estimating equation, and construct confidence intervals from both methods. In the simulation studies, we compare the empirical likelihood (EL) and the Wald-type procedure in terms of coverage accuracy and average length of confidence int
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16

Lu, Min. "A Study of the Calibration Regression Model with Censored Lifetime Medical Cost." Digital Archive @ GSU, 2006. http://digitalarchive.gsu.edu/math_theses/14.

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Medical cost has received increasing interest recently in Biostatistics and public health. Statistical analysis and inference of life time medical cost have been challenging by the fact that the survival times are censored on some study subjects and their subsequent cost are unknown. Huang (2002) proposed the calibration regression model which is a semiparametric regression tool to study the medical cost associated with covariates. In this thesis, an inference procedure is investigated using empirical likelihood ratio method. The unadjusted and adjusted empirical likelihood confidence regions
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17

Kelly, Jodie. "Topics in the statistical analysis of positive and survival data." Thesis, Queensland University of Technology, 1998.

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18

Assareh, Hassan. "Bayesian hierarchical models in statistical quality control methods to improve healthcare in hospitals." Thesis, Queensland University of Technology, 2012. https://eprints.qut.edu.au/53342/1/Hassan_Assareh_Thesis.pdf.

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Quality oriented management systems and methods have become the dominant business and governance paradigm. From this perspective, satisfying customers’ expectations by supplying reliable, good quality products and services is the key factor for an organization and even government. During recent decades, Statistical Quality Control (SQC) methods have been developed as the technical core of quality management and continuous improvement philosophy and now are being applied widely to improve the quality of products and services in industrial and business sectors. Recently SQC tools, in particular
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19

Chang, Yin-Chu, and 張茵筑. "Joint analysis of longitudinal and interval-censored failure time data." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/72nher.

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20

Huang, Jin-long, and 黃進龍. "Nonparametric tests for interval-censored failure time data via multiple imputation." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/am7z65.

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博士<br>國立中山大學<br>應用數學系研究所<br>96<br>Interval-censored failure time data often occur in follow-up studies where subjects can only be followed periodically and the failure time can only be known to lie in an interval. In this paper we consider the problem of comparing two or more interval-censored samples. We propose a multiple imputation method for discrete interval-censored data to impute exact failure times from interval-censored observations and then apply existing test for exact data, such as the log-rank test, to imputed exact data. The test statistic and covariance matrix are calculated by
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21

Sun, De-Yu, and 孫德宇. "Generalized rank tests for univariate and bivariate interval-censored failure time data." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/66877955733235934635.

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碩士<br>國立中山大學<br>應用數學系研究所<br>91<br>In Part 1 of this paper, we adapt Turnbull’s algorithm to estimate the distribution function of univariate interval-censored and truncated failure time data. We also propose four non-parametric tests to test whether two groups of the data come from the same distribution. The powers of proposed test statistics are compared by simulation under different distributions. The proposed tests are then used to analyze an AIDS study. In Part 2, for bivariate interval-censored data, we propose some models of how to generate the data and several methods to measure the
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22

Hsu, Hung-Yen, and 許鴻彥. "The distribution of a non-parametric test for interval-censored failure time data." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/46813527210810946696.

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碩士<br>國立中山大學<br>應用數學系<br>87<br>A generalized non-parametric test for the interval-censored failure time data is proposed in determining whether p lifetime populations come from the same distribution. However, the distribution of a non-parametric statistic is not easy to obtain, therefore a simulation study is necessary. In this article, we propose a simulation procedure for determining the failure time distribution based on discrete interval-censored failure time data. The simulation results indicate that the proposed test is approximately chi-square distribution with (p-1) degree of freedom t
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23

Luh, Horng-Huey, and 陸虹惠. "The distribution of a non-parametric test for interval-censored and truncated failure time data." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/19381589012742766359.

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碩士<br>國立中山大學<br>應用數學系<br>87<br>In this paper, we discuss the distribution of a non-parametric test based on incomplete data for which the measurement of a survival time is known only to belong to an interval. Also the survival time of interest itself is observed from a truncated distribution and is known only to lie in an interval. The test is proposed in determining whether p lifetime populations come from the same distribution. To find the distribution of the test statistic we propose a simulation study. Simulation results indicate that the test is approximately (1/c) multiply chi-square dis
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24

Kuo, Yu-Yu, and 郭育佑. "A generalization of rank tests based on interval-censored failure time data and its application to AIDS studies." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/60525455288344490979.

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碩士<br>國立中山大學<br>應用數學系研究所<br>88<br>In this paper we propose a generalized rank test based on discrete interval-censored failure time data to determine whether two lifetime populations come from the same distribution. It reduces to the Logrank test or Wilcoxon test when one has exact or right-censored data. Simulation shows that the proposed test performs pretty satisfactory. An example is presented to demonstrate how the proposed test can be applied in AIDS study.
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25

Han, Baoguang. "Statistical analysis of clinical trial data using Monte Carlo methods." Thesis, 2014. http://hdl.handle.net/1805/4650.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>In medical research, data analysis often requires complex statistical methods where no closed-form solutions are available. Under such circumstances, Monte Carlo (MC) methods have found many applications. In this dissertation, we proposed several novel statistical models where MC methods are utilized. For the first part, we focused on semicompeting risks data in which a non-terminal event was subject to dependent censoring by a terminal event. Based on an illness-death multistate survival model, we proposed flexible random effects mo
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