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Journal articles on the topic 'Center for Neurologic Study Lability Scale'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Durant, J., L. Bennett, C. Bernick, and J. Miller. "B-59 Prevalence of Pseudobulbar Affect Symptoms in Professional Fighters." Archives of Clinical Neuropsychology 34, no. 6 (2019): 1005. http://dx.doi.org/10.1093/arclin/acz034.142.

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Abstract Objective Pseudobulbar Affect (PBA) is defined as dysregulation of emotional expression and is characterized by sudden, uncontrollable, laughing and/or crying that is discordant with the present mood or social context. This study sought to establish the prevalence of PBA symptoms in individuals with a high incidence of sports-related head injuries and explore the relationship between two rating scales designed to measure PBA symptoms. Methods Sixty-three professional fighters (age: M = 44.7, SD = 10.0; 98% male) underwent neurological and neuropsychological assessment including comple

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Doody, Rachelle S., Stephen D’Amico, Andrew J. Cutler, et al. "An open-label study to assess safety, tolerability, and effectiveness of dextromethorphan/quinidine for pseudobulbar affect in dementia: PRISM II results." CNS Spectrums 21, no. 6 (2015): 450–59. http://dx.doi.org/10.1017/s1092852915000620.

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BackgroundDextromethorphan (DM)/quinidine (Q) is an approved treatment for pseudobulbar affect (PBA) based on trials in amyotrophic lateral sclerosis or multiple sclerosis. PRISM II evaluated DM/Q effectiveness and tolerability for PBA secondary to dementia, stroke, or traumatic brain injury; dementia cohort results are reported.MethodsThis was an open-label, multicenter, 90 day trial; patients received DM/Q 20/10 mg twice daily. Primary outcome was change in Center for Neurologic Study–Lability Scale (CNS-LS) score. Secondary outcomes included PBA episode count and Clinical and Patient/Caregi

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Liu, Ann Wujing, and Kok Hwee Chia. "Joker's Laughter Complex or Pseudobulbar Affect?" Asian Educational Therapist 3, no. 1 (2025): 34–36. https://doi.org/10.5281/zenodo.15455661.

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This paper begins with a case of a 10-year-old autistic child, who exhibits unpredictable laughter for no obvious reason, to the embarrassment of his parents, especialy when the family is in the public area. What is known as the Joker’s Laughter Complex- a form of psychological complex- is a rarely understood condition of pseudobulbar affect (PBA).

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de Similien, Ralph, Milania D. Al-Jammaly, Iuliana Predescu, and Louis Belzie. "Pseudobulbar Affect Symptoms in Nursing Home Patients with Neurocognitive Disorders." Clinical Medicine Insights: Psychiatry 12 (January 2021): 117955732198969. http://dx.doi.org/10.1177/1179557321989691.

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Background: Symptoms of pseudobulbar affect (PBA) often are misinterpreted as those of a mood disorder. Symptoms seen in patients with PBA can be influenced by a mood disorder and vice versa. Our aim in this study was to determine the occurrence rate of PBA symptoms and comorbid depressive symptoms in a cohort of nursing home patients with different subtypes of neurocognitive disorders (NCD)/dementia. Methods: Eighty patients were screened and 61 met the inclusion criteria. These individuals were divided into 5 groups according to NCD subtypes: Alzheimer’s disease, vascular, HIV, unspecified,

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Alet, Matías, Constanza Segamarchi, Santiago Claverie, Leonardo González, Sandra Lepera, and Raúl Rey. "Síndrome pseudobulbar en pacientes con accidente cerebrovascular en Argentina." Vertex Revista Argentina de Psiquiatría 30, no. 148 (2019): 415–19. http://dx.doi.org/10.53680/vertex.v30i148.123.

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Introducción y objetivo: El síndrome pseudobulbar se define por episodios involuntarios o exagerados de risa o llanto, posteriores a una enfermedad específica. El síndrome pseudobulbar después del accidente cerebrovascular se reporta entre el 11%-34% de los pacientes. En nuestra población está subdiagnosticado. Determinamos su frecuencia en un grupo de pacientes post-ACV. Pacientes y métodos: Estudio observacional prospectivo desde junio/2017 a junio/2018. Se evaluaron dos poblaciones: ACV crónico (Grupo A) y ACV agudo (Grupo B). Se excluyeron pacientes con enfermedad psiquiátrica grave, deter

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Yusari, I. Gusti Agung Ayu Andra, and Anak Agung Ayu Putri Laksmidewi. "PSEUDOBULBAR AFFECT AND COGNITIVE DECLINE POST SEVERE TRAUMATIC BRAIN INJURY: A CASE REPORT." MNJ (Malang Neurology Journal) 10, no. 2 (2024): 168–71. http://dx.doi.org/10.21776/ub.mnj.2024.010.02.15.

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Introduction: Pseudobulbar affect is described as episodes of laughing or crying that occur suddenly and uncontrollably without appropriate stimulation. Pseudobulbar affect is often preceded by various neurological disorders, one of which is a history of severe head injury. Case Report: Female, 21 years old, experienced sudden frequent laughing for no apparent reason and could not be controlled. This has been happening after she suffered a severe head injury, which was a subarachnoid hemorrhage, about two years ago. She was diagnosed with pseudobulbar affect according to Cummings criteria and

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Fitzgerald, Kathryn C., Amber Salter, Tuula Tyry, Robert J. Fox, Gary Cutter, and Ruth Ann Marrie. "Pseudobulbar affect." Neurology: Clinical Practice 8, no. 6 (2018): 472–81. http://dx.doi.org/10.1212/cpj.0000000000000523.

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BackgroundWe sought to determine the prevalence of pseudobulbar affect (PBA) in a large MS population and assess its association with disability and symptom severity.MethodsNorth American Research Committee on MS (NARCOMS) registry participants completed the Center for Neurologic Study-Lability Scale (CNS-LS), a validated 7-question self-report measure of PBA. A composite PBA score was derived from the sum of responses to the 7 questions. We categorized individuals as PBA-positive (PBA[+]) if they had a composite score ≥17 without current depression. Participants also reported their demographi

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Demir, Serkan, Asli Koskderelioglu, Mustafa Karaoglan, Muhtesem Gedizlioglu, and Rifat Erdem Togrol. "Pseudobulbar affect prevalence in Turkish multiple sclerosis patients." Medical Science and Discovery 5, no. 7 (2018): 279–83. https://doi.org/10.36472/msd.v5i7.265.

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Objective: Pseudobulbar affect (PBA) is characterized by uncontrolled crying or laughing attacks which are usually socially inappropriate. The estimated prevalence in patients with multiple sclerosis (MS) ranges from 10% to 46.2%. We conducted a cross-sectional study to evaluate the prevalence of PBA in the Turkish MS population. Also, we aimed to estimate whether there was gender preference or coexistent depression. Material and Methods: We used the Center for Neurologic Study - Lability Scale (CNS-LS) for this study. We included patients who were followed up at our outpatient clinic of Sulta

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Ahmad, Umar, and Alan R. Hirsch. "193 A New Syndrome: Phantogeusia-Induced Phantosmia." CNS Spectrums 23, no. 1 (2018): 110. http://dx.doi.org/10.1017/s1092852918000731.

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AbstractCase ObjectiveWhile phantosmia-induced phantogeusia has been described (Ahmed, 20173), the reverse, phantogeusia-induced phantosmia, has not heretofore been described. Such a case is presented.MethodsCase Study: A 39-yr-old left-handed (pathological) male, six years prior to presentation, noted a sudden onset of phantogeusia of roast cooking, pizza, fruit, strawberries, or a sour taste, and shortly thereafter he would develop unpleasant phantosmias which would sometimes combine with the ambient aroma. These would occur 3-10 times per week and would last for the duration of the phantoge

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Nayati, Jasir T., Syed Mohyuddin, Tajinder Parhar, Ather M. Ali, and Alan R. Hirsch. "25 Ventriculoperitoneal Shunt as a Meteorologist: Medtronics Shunt Headaches Vaticinating Climatic Perturbation." CNS Spectrums 24, no. 1 (2019): 186–87. http://dx.doi.org/10.1017/s1092852919000191.

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AbstractIntroductionNeurological conditions can be influenced by meteorological parameters. Some may predict weather changes, such as migraines [Marrelli 1988], burning mouth syndrome [Hirsch 2017], phantosmia [Hirsch 2013], and Bell’s Palsy [Danielides 2001]. However, climatic conditions inducing headaches in those with ventriculoperitoneal shunt (VPS) placements have not heretofore been described.MethodsA 46-year-old female presented with epochs of headaches coinciding with climatic changes. She had hydrocephalus secondary to infantile meningitis that was treated with a Medtronics Strata II

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Dhillon, Davinder, Jasir T. Nayati, Priya Batta, and Alan R. Hirsch. "124 Epochs of Anosmia and Ageusia in Multiple Sclerosis: Chemosensory Uhthoff’s Phenomenon." CNS Spectrums 23, no. 1 (2018): 78–79. http://dx.doi.org/10.1017/s1092852918000226.

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AbstractStudy ObjectiveTo reveal that while long duration of anosmia and ageusia has been seen with Multiple Sclerosis (MS) [Doty 1997], repetitive shorter epochs ofanosmia and ageusia has not heretofore been presented.MethodsCase Study: A 39 year old right-handed male, with a history of MS, presents with six years MS concurrent with epochs of anosmia and ageusia. The anosmia andageusia present concurrently, preventing him from smelling and tasting his meal. At baseline, he is able to smell and taste coffee, peppermint, gum, sweet and salty foods, rating his smell and taste at 70% normal. Howe

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Dhillon, Davinder, Priya Batta, and Alan R. Hirsch. "125 Short Duration Monoballismus." CNS Spectrums 23, no. 1 (2018): 79–80. http://dx.doi.org/10.1017/s1092852918000238.

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AbstractStudy ObjectiveWhile monoballismus has been reported to be associated with hemorrhagic lesions in the subthalamic nucleus (Ohnishi, 2009) and multiple sclerosis (MS) (Rosa, 2011), the duration has been reported to be at least six days (Soysal, 2012). A patient with epochs of monoballismus lasting for 45 minutes is presented.MethodsCase Study: A 57 year old right handed female with attention deficit hereditary disorder predominantly inattentive on amphetamine sulphate, presented with two years of memory loss. For instance, after ordering food in restaurants, by the time the food arrives

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Nayati, Jasir T., and Alan R. Hirsch. "136 CerefolinNAC Therapy-Induced Dizziness." CNS Spectrums 23, no. 1 (2018): 85–86. http://dx.doi.org/10.1017/s1092852918000329.

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AbstractStudy ObjectiveCerefolinNAC (CFLN-NAC) contains L-methylfolate (6 mg), methylcobalamin (2 mg), and N-acetylcysteine [NAC] (600 mg) [Pamlab 2017]. Dizziness and lightheadedness have not heretofore been described with use of CFLN-NAC.MethodsCase Study: A 64 year old right-handed female was started on CFLN-NAC for smell and taste issues. Over a three day period, she experienced a gradual increase in dizziness. This was a non-vertiginous lightheadedness, so severe that she was unable to walk, and would lie down the entire day to alleviate the dizziness. It was associated with nausea, but w

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Dulay, Mario F., Jennifer L. Thompson, Tracey H. Hicks, Emma Lai, and Jerome S. Caroselli. "1 Post-stroke Apathy, Pseudobulbar Affect and Memory Loss Hinder Return-to-Work After CVA." Journal of the International Neuropsychological Society 29, s1 (2023): 301–2. http://dx.doi.org/10.1017/s1355617723004216.

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Objective:Post-stroke depression (PSD) and anxiety disorders are the most common psychiatric issues that occur after cerebrovascular accident (CVA), with prevalence rates of up to 50%. Less studied, post-stroke apathy and pseudobulbar affect (PBA) also occur in a subset of individuals after CVA leading to reduced quality of life. Cognitive impairments also persist, especially memory, language, and executive difficulties. Residual cognitive and emotional sequelae after CVA limit return-to-work with between 20-60% becoming disabled or retiring early. This study examined the frequency and relativ

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Chi, Yesung, and Alan R. Hirsch. "Resolution of COVID-19 Chemosensory Loss Upon COVID-19 Reinfection." CNS Spectrums 29, no. 5 (2024): 521. https://doi.org/10.1017/s1092852924002001.

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IntroductionThe pandemic of coronavirus disease 2019 (COVID-19) has been associated with widespread myriad chemosensory dysfunction with smell loss as high as 99% and taste loss in 89% of those studied (Kim 2021, Paderno 2020, Renaud 2020). Other chemosensory problems, occur often in combination, including dysgeusia and hyposmia (3.2%), dysgeusia and anosmia (3.4%), ageusia and hyposmia (3.4%) and, ageusia and anosmia (8.5%) (Giacomelli, 2020). Hyperosmia has also been reported to be precipitated by COVID-19 infection (Di Stadio 2022, Kamali 2021). COVID-19 induced persistent hyposmia with res

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Lim Fat, M., R. Fox, M. Allen, et al. "P11.63.B VALIDATING THE NEUROLOGIC ASSESSMENT IN NEURO-ONCOLOGY (NANO) SCALE IN CLINICAL PRACTICE: A MULTI-CENTER PROSPECTIVE STUDY IN PATIENTS WITH GLIOBLASTOMA." Neuro-Oncology 25, Supplement_2 (2023): ii89. http://dx.doi.org/10.1093/neuonc/noad137.297.

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Abstract BACKGROUND The neurologic assessment in neuro-oncology (NANO) scale was developed as a standardized metric to objectively measure neurologic function in patients with brain tumors and complement radiographic assessment in defining overall outcomes. The scale has been incorporated in clinical trials, however, real-world use of the NANO scale to drive clinical decision-making and the predictive value of the NANO scale to determine overall survival remains unclear in glioblastoma. MATERIAL AND METHODS We report on an ongoing multi-center study of prospective NANO score collection to eval

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Smith, Richard A., James E. Berg, Laura E. Pope, Janice D. Callahan, Daniel Wynn, and Ronald A. Thisted. "Validation of the CNS emotional lability scale for pseudobulbar affect (pathological laughing and crying) in multiple sclerosis patients." Multiple Sclerosis Journal 10, no. 6 (2004): 679–85. http://dx.doi.org/10.1191/1352458504ms1106oa.

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Pseudobulbar affect (PBA) or pathological laughing and crying (PLC) is a disorder of affect that occurs in about 10% of multiple sclerosis (MS) patients. The objective of this study was to validate the CNS Emotional Lability Scale (CNS-LS) in MS patients and to correlate the results with the frequency and intensity of episodes of PLC. Physicians at seven private practice referral centers in the United States made a diagnosis concerning PLC based on patient interviews. Clinical coordinators separately administered the CNS-LS, a self-report measure of PLC with seven questions, to MS patients, in

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Misra, Usha Kant, Jayantee Kalita, Rajesh Kumar Singh, and Sanjeev Kumar Bhoi. "A Study of Hyponatremia in Acute Encephalitis Syndrome: A Prospective Study From a Tertiary Care Center in India." Journal of Intensive Care Medicine 34, no. 5 (2017): 411–17. http://dx.doi.org/10.1177/0885066617701422.

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Purpose: To evaluate the frequency and causes of hyponatremia in acute encephalitis syndrome (AES) and its effect on outcome. Patients and Methods: Consecutive patients with AES were subjected to neurological evaluation including Glasgow Coma Scale, focal weakness, movement disorder, and reflex changes. The etiology of AES was based on blood and cerebrospinal fluid enzyme-linked immunosorbent assay and polymerase chain reaction. We have categorized patients into neurological or systemic AES. Hyponatremia was diagnosed if 2 consecutive serum sodium levels were below 135 mEq/L, 24 hours apart. S

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Kögl, Nikolaus, Konstantin Brawanski, Pierre-Pascal Girod, Ondra Petr, and Claudius Thomé. "Early surgery determines recovery of motor deficits in lumbar disc herniations—a prospective single-center study." Acta Neurochirurgica 163, no. 1 (2020): 275–80. http://dx.doi.org/10.1007/s00701-020-04614-0.

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Abstract Background Patients with intervertebral disc herniation undergo surgical removal of herniated disc material in cases of persisting symptoms and/or neurologic deficits. While motor deficits often prompt surgery, little is known about the optimal timing of surgery in these cases. The aim of this study was to prospectively evaluate the impact of timing of disc surgery on motor recovery. Does postponing surgical treatment worsen outcome? Method In total, 120 patients with sciatica and/or sensorimotor deficits due to a lumbar disc herniation were surgically treated at the authors’ center w

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Smith, R. A., E. A. Macklin, K. J. Myers, et al. "Assessment of bulbar function in amyotrophic lateral sclerosis: validation of a self-report scale (Center for Neurologic Study Bulbar Function Scale)." European Journal of Neurology 25, no. 7 (2018): 907—e66. http://dx.doi.org/10.1111/ene.13638.

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Capecci, Marianna, Nicolò Baldini, Francesca Campignoli, Lorenzo Pasquale Lombardo, Elisa Andrenelli, and Maria Gabriella Ceravolo. "Clinical and Functional Evolution in Subjects with Parkinson’s Disease during SARS-CoV-2 Pandemic." Applied Sciences 13, no. 2 (2023): 1126. http://dx.doi.org/10.3390/app13021126.

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The COVID-19 pandemic has been a stress test for the population, especially for people with chronic disorders such as Parkinson’s disease (PD). In addition to public health restrictions that contrast with PD management recommendations, there were deep changes in health care delivery. This retrospective study evaluates the impact of COVID-19 on the clinical and functional evolution of a cohort of 221 PD patients consecutively referred to the Movement Disorders Center between 2018 and 2021. We analyzed the trend in motor and non-motor symptoms and functional status across years based on the Unif

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Hanzlik, Emily, Stuart McAfee, Matt Scoggins, et al. "NCOG-11. FACTORS PREDICTING SPEECH AND GAIT RECOVERY IN CHILDREN WITH POST-OPERATIVE POSTERIOR FOSSA SYNDROME (PFS)." Neuro-Oncology 26, Supplement_8 (2024): viii226. http://dx.doi.org/10.1093/neuonc/noae165.0893.

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Abstract Posterior fossa syndrome/cerebellar mutism syndrome is a surgical complication of posterior fossa tumor resection, especially midline tumors. Initially thought to involve complete mutism, PFS is now recognized as a complex syndrome involving loss of language (complete [PFS1] and incomplete [PFS2]). Additional symptoms include apraxia, movement disorder, motor and coordination deficits, and emotional lability. The aim of this study was to identify factors that influence delayed speech and independent gait recovery in children with PFS. We prospectively studied 73 children ≥3 years of a

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Lee, Yun Im, Ryoung-Eun Ko, Joonghyun Ahn, Keumhee C. Carriere, and Jeong-Am Ryu. "Association between Neurologic Outcomes and Changes of Muscle Mass Measured by Brain Computed Tomography in Neurocritically Ill Patients." Journal of Clinical Medicine 11, no. 1 (2021): 90. http://dx.doi.org/10.3390/jcm11010090.

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This study aimed to investigate whether skeletal muscle mass estimated via brain computed tomography (CT) could predict neurological outcomes in neurocritically ill patients. This is a retrospective, single-center study. Adult patients admitted to the neurosurgical intensive care unit (ICU) from January 2010 to September 2019 were eligible. Cross-sectional areas of paravertebral muscles at the first cervical vertebra level (C1-CSA) and temporalis muscle thickness (TMT) on brain CT were measured to evaluate skeletal muscle mass. The primary outcome was the Glasgow Outcome Scale score at 3 month

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de Celis-Ruiz, Elena, Blanca Fuentes, María Alonso de Leciñana, et al. "Final Results of Allogeneic Adipose Tissue–Derived Mesenchymal Stem Cells in Acute Ischemic Stroke (AMASCIS): A Phase II, Randomized, Double-Blind, Placebo-Controlled, Single-Center, Pilot Clinical Trial." Cell Transplantation 31 (January 2022): 096368972210838. http://dx.doi.org/10.1177/09636897221083863.

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Acute ischemic stroke is currently a major cause of disability despite improvement in recanalization therapies. Stem cells represent a promising innovative strategy focused on reduction of neurologic sequelae by enhancement of brain plasticity. We performed a phase IIa, randomized, double-blind, placebo-controlled, single-center, pilot clinical trial. Patients aged ≥60 years with moderate to severe stroke (National Institutes of Health Stroke Scale [NIHSS] 8–20) were randomized (1:1) to receive intravenous adipose tissue–derived mesenchymal stem cells (AD-MSCs) or placebo within the first 2 we

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Park, Bu Kyung, Seong-il Oh, Minsung Kang, et al. "Reliability and Validity of the Korean version of the Center for Neurologic Study Bulbar Function Scale (K-CNS-BFS): An observational study." Medicine 103, no. 25 (2024): e38216. http://dx.doi.org/10.1097/md.0000000000038216.

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Bulbar dysfunction in amyotrophic lateral sclerosis (ALS) significantly affects daily life, leading to weight loss and reduced survival. Methods for evaluating bulbar dysfunction, including videofluoroscopic swallowing studies and the bulbar component of the ALS Functional Rating Scale-Revised (ALSFRS-R), have been employed; however, Korean-specific tools are lacking. The Center for Neurologic Study Bulbar Function Scale (CNS-BFS) comprehensively evaluates bulbar symptoms. This study aimed to develop and validate the Korean version of the CNS-BFS (K-CNS-BFS) to assess bulbar dysfunction in Kor

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Kharlamenkova, N. E., O. S. Zaitsev, D. A. Nikitina, and A. N. Kormilitsyna. "Emotional Personality Characteristics of Patients Diagnosed with Meningioma with Severe Post-Traumatic Stress." Клиническая и специальная психология 7, no. 4 (2018): 150–67. http://dx.doi.org/10.17759/cpse.2018070409.

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The results of the study on post-traumatic stress rates and individual indicators arising in response to the diagnosis of a life-threatening disease are being analyzed. The participants of the study are the patients of Burdenko National Medical Research Center of Neurosurgery, Ministry of Health of the Russian Federation (n = 25) diagnosed with meningioma. It has been shown that one of the psychological consequences of the diagnosis of “meningioma” is post-traumatic stress of different intensity rates. Increased depression, shyness and emotional lability are associated with high post-traumatic

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Jadhav, Ashutosh, David Panczykowski, Mouhammad Jumaa, et al. "Angioplasty and stenting for symptomatic extracranial non-tandem internal carotid artery occlusion." Journal of NeuroInterventional Surgery 10, no. 12 (2018): 1155–60. http://dx.doi.org/10.1136/neurintsurg-2018-013810.

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IntroductionSymptomatic internal carotid artery occlusion (ICAO) can lead to neurologic decline, recurrent stroke, and mortality.ObjectiveWe sought to evaluate the safety and feasibility of endovascular revascularization for ICAO without tandem intracranial large vessel occlusion (LVO).Design, setting, and participantsThis is a retrospective cohort analysis of all patients presenting to a single academic center with ischemic stroke and ipsilateral cervical ICAO from November 2003 through April 2016. Patients were excluded if pre-procedural angiography demonstrated tandem LVO or if patients wer

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Hsieh, Emory, Tito Mendoza, Dhaivat Raval, et al. "NCOG-28. SERUM PROTEIN BIOMARKERS LINKED TO NEURODEGENERATIVE PROCESSES ARE ELEVATED IN GLIOMA PATIENTS AND ASSOCIATED WITH SEVERITY OF NEUROLOGIC SYMPTOMS." Neuro-Oncology 26, Supplement_8 (2024): viii230. http://dx.doi.org/10.1093/neuonc/noae165.0910.

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Abstract BACKGROUND Glioma patients frequently report neurologic symptoms, adding to the complexity of cancer management and negatively impacting quality of life. However, mechanisms associated with the development of neurologic symptoms in glioma patients remain unclear. Pathological changes in the brain of glioma patients might result in elevated peripheral blood levels of proteins previously linked to central nervous system (CNS) damage and neurodegeneration, including neurofilament light chain (NfL), tau, and glial fibrillary acidic protein (GFAP). Here, we tested the hypothesis that the c

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Biswas, Konish, Sanjay Agrawal, Priyanka Gupta, and Rajnish Arora. "Evaluation of risk factors for postoperative neurologic intensive care admission after brain tumor craniotomy: A single-center longitudinal study." Journal of Anaesthesiology Clinical Pharmacology 40, no. 2 (2024): 217–27. http://dx.doi.org/10.4103/joacp.joacp_323_22.

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Abstract Background and Aims: Perioperative variable parameters can be significant risk factors for postoperative intensive care unit (ICU) admission after elective craniotomy for intracranial neoplasm, as assessed by various scoring systems such as Cranio Score. This observational study evaluates the relationship between these factors and early postoperative neurological complications necessitating ICU admission. Material and Methods: In total, 119 patients, aged 18 years and above, of either sex, American Society of Anesthesiologists (ASA) grades I–III, scheduled for elective craniotomy and

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Cioca, Ioana Elena, Maria-Veronica Morcov, Corina Sporea, et al. "Parenting Styles and Parental Self-Efficacy in Parents of Children with Neurological Disorders." Balneo and PRM Research Journal 16, Vol 16 No. 1 (2025): 778. https://doi.org/10.12680/balneo.2025.778.

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This study examines the influence of different parenting styles on parental self-efficacy in families with children diagnosed with neurologic disorders. Specifically, it explores the correlation between five distinct styles—authoritarian, authoritative, permissive, perfectionist, and uninvolved—and parental confidence in managing the challenges associated with raising children with disabilities. The study involved 134 parents of children with neurologic disorders and was conducted in a specialized medical rehabilitation center for children in Bucharest, Romania. Data was collected using the Pa

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Schriefl, Christoph, Christian Schoergenhofer, Nina Buchtele, et al. "Out-of-Sample Validity of the PROLOGUE Score to Predict Neurologic Function after Cardiac Arrest." Journal of Personalized Medicine 12, no. 6 (2022): 876. http://dx.doi.org/10.3390/jpm12060876.

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Background: The clinical value of a prognostic score depends on its out-of-sample validity because inaccurate outcome prediction can be not only useless but potentially fatal. We aimed to evaluate the out-of-sample validity of a recently developed and highly accurate Korean prognostic score for predicting neurologic outcome after cardiac arrest in an independent, plausibly related sample of European cardiac arrest survivors. Methods: Analysis of data from a European cardiac arrest center, certified in compliance with the specifications of the German Council for Resuscitation. The study sample

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de Castro-Afonso, Luis Henrique, Guilherme Seizem Nakiri, Thiago Giansante Abud, et al. "Treatment of distal unruptured intracranial aneurysms using a surface-modified flow diverter under prasugrel monotherapy: a pilot safety trial." Journal of NeuroInterventional Surgery 13, no. 7 (2021): 647–51. http://dx.doi.org/10.1136/neurintsurg-2020-017262.

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BackgroundFlow diverters (FDs) are effective in the treatment of carotid aneurysms. Compared with carotid aneurysms, the treatment of distal intracranial aneurysms with FDs has been associated with a relatively high incidence of complications. Low thrombogenic modified-surface FDs may reduce ischemic complications and allow for the use of a single antiplatelet medication. The aim of this study was to assess the safety and efficacy of the p48 MW HPC Flow Modulation Device (Phenox GmbH, Bochum, Germany) to treat distal intracranial aneurysms used in combination with prasugrel monotherapy.Methods

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Cho, Yongjae. "Posterior Vertebrectomy and Circumferential Fusion for the Treatment of Advanced Thoracolumbar Kümmell Disease with Neurologic Deficit." Asian Spine Journal 11, no. 4 (2017): 634–40. http://dx.doi.org/10.4184/asj.2017.11.4.634.

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<sec><title>Study Design</title><p>Single-center, retrospective case series.</p></sec><sec><title>Purpose</title><p>To investigate the effectiveness of posterior vertebrectomy and circumferential fusion in patients with advanced Kümmell disease with neurologic deficit.</p></sec><sec><title>Overview of Literature</title><p>Various surgical options exist for the treatment of Kümmell disease, and determination of the appropriate treatment is based on the clinical and radiologic status of the patient. H

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Kalasauskas, Darius, Naureen Keric, Salman Abu Ajaj, Leoni von Cube, Florian Ringel, and Mirjam Renovanz. "Psychological Burden in Meningioma Patients under a Wait-and-Watch Strategy and after Complete Resection Is High—Results of a Prospective Single Center Study." Cancers 12, no. 12 (2020): 3503. http://dx.doi.org/10.3390/cancers12123503.

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The diagnosis of intracranial meningiomas as incidental findings is increasing by growing availability of MRI diagnostics. However, the psychological distress of patients with incidental meningiomas under a wait-and-watch strategy is unknown. Therefore, we aimed to compare the psychosocial situation of meningioma patients under wait-and-watch to patients after complete resection to bridge this gap. The inclusion criteria for the prospective monocenter study were either an incidental meningioma under a wait-and-watch strategy or no neurologic deficits after complete resection. Sociodemographic,

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Cao, Xiangyu, Jun Wang, Chenglin Tian, et al. "Solitaire AB stent-angioplasty for stenoses in perforator rich segments: A single-center experience." Interventional Neuroradiology 26, no. 5 (2020): 608–14. http://dx.doi.org/10.1177/1591019920951651.

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Background Vascular angioplasty and stenting of middle cerebral artery (MCA) and basilar artery (BA) stenoses are associated with poor clinical outcomes and high mortality rates thought to be related to the abundance of perforating arteries in those segments. This study explores the use of Solitaire AB as an off-label vascular stent to treat stenoses in the MCA and BA. Methods Solitaire AB stents were placed during angioplasty and stenting of MCA and BA stenoses in patients at our department between January 2015 and May 2017 with 6-36 months follow-up. Operative results were assessed by follow

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Parma, Carolyn, Daniel Carney, Rod Grim, Ted Bell, Kimberly Shoff, and Vanita Ahuja. "Unnecessary Head Computed Tomography Scans: A Level 1 Trauma Teaching Experience." American Surgeon 80, no. 7 (2014): 664–68. http://dx.doi.org/10.1177/000313481408000720.

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The Canadian CT Head Rule attempts to standardize the practice of obtaining head computed tomography (CT) scans in patients with minor head injury. Previous research indicates 10 to 35 per cent of CT scans performed do not meet these guidelines. The purpose of this study was to review our use of CT scans in the evaluation of mild traumatic brain injury and to identify 1) unnecessary head CT scans (UHCT); 2) variables associated with UHCT; and 3) associated costs. Using a trauma registry, inclusion criteria were age older than 18 years, Glasgow Coma Scale of 15, and at least one head CT scan. U

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Farina, Antonio, Macarena Villagrán-García, Nicolás Lundahl Ciano-Petersen, et al. "Anti-Hu Antibodies in Patients With Neurologic Side Effects of Immune Checkpoint Inhibitors." Neurology - Neuroimmunology Neuroinflammation 10, no. 1 (2022): e200058. http://dx.doi.org/10.1212/nxi.0000000000200058.

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Background and ObjectivesTo clinically characterize post–immune checkpoint inhibitor (ICI) Hu antibody (Ab) neurologic disorders, we analyzed Hu-Ab–positive patients with neurologic immune-related adverse events (n-irAEs) and compared them with patients with other n-irAEs, ICI-naive patients with Hu-Ab paraneoplastic neurologic syndromes (PNSs) identified in the same study center, and those with Hu-Ab n-irAEs reported elsewhere.MethodsPatients whose samples were sent to the French reference center for a suspicion of n-irAE (2015–2021) were identified; those with a final diagnosis of n-irAE and

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Misirlioglu, Merve, Faruk Ekinci, Dincer Yildizdas, et al. "A Retrospective Cohort Study of Traumatic Brain Injury in Children: A Single-Institution Experience and Determinants of Neurologic Outcome." Journal of Critical Care Medicine 9, no. 4 (2023): 252–61. http://dx.doi.org/10.2478/jccm-2023-0027.

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Abstract Introduction Traumatic brain injury (TBI) has become a significant cause of death and morbidity in childhood since the elucidation of infectious causes within the last century. Mortality rates in this population decreased over time due to developments in technology and effective treatment modalities. Aim of the study This retrospective cohort study aimed to describe the volume, severity and mechanism of all hospital-admitted pediatric TBI patients at a university hospital over a 5-year period. Material and Methods This was a single-center, retrospective cohort study including 90 pedia

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Benussi, Alberto, Andrea Pilotto, Enrico Premi, et al. "Clinical characteristics and outcomes of inpatients with neurologic disease and COVID-19 in Brescia, Lombardy, Italy." Neurology 95, no. 7 (2020): e910-e920. http://dx.doi.org/10.1212/wnl.0000000000009848.

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ObjectiveTo report clinical and laboratory characteristics, treatment, and clinical outcomes of patients admitted for neurologic diseases with and without coronavirus disease 2019 (COVID-19).MethodsIn this retrospective, single-center cohort study, we included all adult inpatients with confirmed COVID-19 admitted to a neuro-COVID unit beginning February 21, 2020, who had been discharged or died by April 5, 2020. Demographic, clinical, treatment, and laboratory data were extracted from medical records and compared (false discovery rate corrected) to those of neurologic patients without COVID-19

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Misasi, Adam, Jeanette G. Ward, Fanglong Dong, Elizabeth Ablah, Chad Maurer, and James M. Haan. "Prehospital Extrication Techniques: Neurological Outcomes Associated with the Rapid Extrication Method and the Kendrick Extrication Device." American Surgeon 84, no. 2 (2018): 248–53. http://dx.doi.org/10.1177/000313481808400233.

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Most emergency medical service personnel rely on one of two techniques to extricate motor vehicle crash victims; the Rapid Extrication Maneuver (REM) or the Kendrick Extrication Device (KED). The purpose of this study was to compare pre- and postextrication neurological outcomes between these two techniques. A retrospective review was conducted of all adult patients with a vertebral column injury resulting from motor vehicle collision and admitted to a Level I trauma center between January 1, 2003 and December 31, 2010. Standardized pre- and postextrication neurological examinations were revie

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Capan, Nalan, Özden Özyemişçi Taşkıran, Evrim Karadağ Saygı, Ebru Yılmaz Yalçınkaya, Berrin Hüner, and Resa Aydın. "The impact of the COVID-19 pandemic on children with disabilities and their parents or caregivers." Turkish Journal of Physical Medicine and Rehabilitation 1, no. 1 (2023): 75–82. http://dx.doi.org/10.5606/tftrd.2023.10193.

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Objectives: The study aimed to determine the impact of the pandemic on parents/caregivers and children with neurologic disabilities. Patients and methods: This multi-center cross-sectional study was conducted with 309 parents/caregivers (57 males, 252 females) and their 309 children (198 males, 111 females) with disabilities between July 5, 2020, and August 30, 2020. The parents/caregivers were able to answer the questions and had internet access. The survey included questions on the utilization of educational and health care services (whether they could obtain medicine, orthosis, botulinum to

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Kotecha, Rupesh, Brian Schiro, Justin Sporrer, et al. "SPIN-01 RADIATION THERAPY ALONE VERSUS RADIATION THERAPY PLUS RADIOFREQUENCY ABLATION/VERTEBRAL AUGMENTATION FOR SPINE METASTASIS: TRIAL IN PROGRESS." Neuro-Oncology Advances 4, Supplement_1 (2022): i11. http://dx.doi.org/10.1093/noajnl/vdac078.042.

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Abstract BACKGROUND Spine metastases are a common occurrence in cancer patients and result in pain, neurologic deficits, decline in performance status, disability, inferior quality of life (QOL), and reduction in ability to receive cancer-directed therapies. Conventional external beam radiation therapy (EBRT) is associated with modest rates of pain relief, high rates of disease recurrence, low response rates for those with radioresistant histologies, and limited improvement in neurologic deficits. The addition of radiofrequency ablation/percutaneous vertebral augmentation (RFA/PVA) to index si

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Tridon, Chloé, Delphine Bachelet, Majda El Baied, et al. "Association of Sepsis With Neurologic Outcomes of Adult Patients Treated With Venoarterial Extracorporeal Membrane Oxygnenation." Critical Care Explorations 6, no. 2 (2024): e1042. http://dx.doi.org/10.1097/cce.0000000000001042.

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OBJECTIVES: Neurologic outcomes of patients under venoarterial extracorporeal membrane oxygenation (VA-ECMO) may be worsened by secondary insults of systemic origin. We aimed to assess whether sepsis, commonly observed during ECMO support, is associated with brain injury and outcomes. DESIGN: Single-center cohort study of the “exposed-non-exposed” type on consecutive adult patients treated by VA-ECMO. SETTING: Medical ICU of a university hospital, France, 2013–2020. PATIENTS: Patients with sepsis at the time of VA-ECMO cannulation (“sepsis” group) were compared with patients without sepsis (“n

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Maytorena, Juan Enrique García, Yanyn Ameyaly Cabrera Antonio, Kassandra Aglae Salazar Vázquez, Arturo Gerardo Garza Alatorre, and Verónica Rodríguez Martínez. "Tomographic index (ONSD/ETD) as a predictor of short-term neurological outcome in children with severe traumatic brain injury: A single-center retrospective observational study from Mexico." Journal of Pediatric Critical Care 11, no. 4 (2024): 137–41. http://dx.doi.org/10.4103/jpcc.jpcc_15_24.

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Abstract Background: Traumatic brain injury (TBI) is a prevalent condition in the pediatric population. An index between the diameter of the optic nerve sheath diameter (ONSD) and the transverse eyeball transverse diameter (ETD) measured in the tomographic scan has been described in adults, with a cutoff value of ≥0.25 for predicting poor neurologic prognoses. This study was conducted to analyze the relationship between the index ONSD/ETD with the neurological outcome in children with severe TBI. Subjects and Methods: This was single-center, retrospective study, conducted from March 2021 to No

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Sassi, Fernanda Chiarion, Ana Paula Ritto, Maíra Santilli de Lima, et al. "Characteristics of postintubation dysphagia in ICU patients in the context of the COVID-19 outbreak: A report of 920 cases from a Brazilian reference center." PLOS ONE 17, no. 6 (2022): e0270107. http://dx.doi.org/10.1371/journal.pone.0270107.

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The purpose of this research was to identify risk factors that were independently related to the maintenance of a swallowing dysfunction in patients affected by critical COVID-19. We conducted a prospective observational cohort study of critical patients with COVID-19, who were admitted to a COVID-19 dedicated intensive care unit (ICU) and required prolonged orotracheal intubation (≥48 hours). Demographic and clinical data were collected at ICU admission and/or at hospital discharge or in-hospital death. Swallowing data was based on The Functional Oral Intake Scale (FOIS) and was collected at

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Tran, Quincy, Hannah Frederick, Cecilia Tran, et al. "Blood Pressure Variability and Outcome in Traumatic Brain Injury: A Propensity Score Matching Study." Western Journal of Emergency Medicine 23, no. 5 (2022): 769–80. http://dx.doi.org/10.5811/westjem.2022.6.55549.

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Introduction: Patients with tIPH (used here to refer to traumatic intraparenchymal hemorrhagic contusion) or intraparenchymal hemorrhage face high rates of mortality and persistent functional deficits. Prior studies have found an association between blood pressure variability (BPV) and neurologic outcomes in patients with spontaneous IPH. Our study investigated the association between BPV and discharge destination (a proxy for functional outcome) in patients with tIPH. Methods: We retrospectively reviewed the charts of patients admitted to a Level I trauma center for ≥ 24 hours with tIPH. We e

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Widyastuti, Yunita, Akhmad Yun Jufan, Untung Widodo, et al. "A tertiary care center-based study of a novel ‘ICU Mortality and Prolonged Stay Risk Scoring System’." Anaesthesia, Pain & Intensive Care 28, no. 1 (2024): 100–107. http://dx.doi.org/10.35975/apic.v28i1.2382.

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Background & objective: Intensive care has been associated with high cost and resource-intensive medical care. Therefore, a risk prediction model is required to plan time allocation, human resources, and the required equipment. Various risk predictions for ICU mortality and ‘Prolonged Length of Stay’ (PLOS) scores are already available. Still, the established model, such as the APACHE IV score or SAPS II, sometimes became impractical since they required many laboratory parameters. A model based on co-morbidities and demographic factors may be more useful in limited resources setting. Hence

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Steenkjær, Christian H., Mia B. Heintzelmann, Izabella Obál, Grethe Andersen, and Jakob U. Blicher. "An adapted Danish translation of the Center for Neurologic Study Lability scale." Danish Medical Journal, May 1, 2025, 1–7. https://doi.org/10.61409/a07240497.

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INTRODUCTION. Pathological crying and/or laughing (pseudobulbar affect (PBA)) are socially debilitating symptoms seen in many neurological diseases, such as stroke, multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS). One method for measuring the degree of PBA is the Center for Neurologic Study-Lability Scale (CNS-LS), a seven-item questionnaire validated for quantifying symptoms and supporting PBA diagnoses in ALS and MS. The aim of this study was to provide a Danish translation of the CNS-LS inspired by international guidelines on cross-cultural translation and adaptation of self

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Chen, Lu, Shan Ye, Davan Murphy, et al. "Chinese Translation and Validation of the Center for Neurologic Study Lability Scale." Neurology and Therapy, April 16, 2024. http://dx.doi.org/10.1007/s40120-024-00605-w.

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Zorowitz, Richard, David Alexander, Paul Shin, et al. "Abstract 107: Dextromethorphan/Quinidine for Treatment of Pseudobulbar Affect Secondary to Stroke: Results from the PRISM-II Study." Stroke 47, suppl_1 (2016). http://dx.doi.org/10.1161/str.47.suppl_1.107.

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Introduction: Pseudobulbar affect (PBA) is characterized by sudden, frequent, uncontrollable laughing/crying episodes that are out of proportion or disconnected from mood or social context. PRISM-II evaluated dextromethorphan/quinidine (DM/Q) effectiveness for PBA secondary to stroke (reported here), dementia, or traumatic brain injury. Hypothesis: DM/Q is effective and well tolerated for PBA secondary to neurologic disease such as stroke. Methods: Open-label, 12-week, US multicenter trial of DM/Q 20/10 mg twice/day (starting once/day in week 1). Eligible patients had PBA with Center for Neuro

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