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Journal articles on the topic 'Central Baptist Association (Ga.)'

Author: Grafiati

Published: 4 June 2021

Last updated: 28 July 2025

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1

Hoyle, Lydia Huffman. "The subversive power of calling: The Girls’ Auxiliary and Baptist women in ministry." Review & Expositor 119, no. 3-4 (2022): 368–79. http://dx.doi.org/10.1177/00346373231169968.

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In the second half of the twentieth century, a group called the Girls’ Auxiliary (GA) became influential in the lives of many Southern Baptist girls and women. Through weekly meetings, annual camps, fund-raising, and individual mission activities, girls learned about how they could make a difference in the world through missions. In Baptist life, mission was the central work of the church. Alongside the Women’s Missionary Union (WMU), which sponsored and led the girls, the GAs brought attention to the mission cause and helped in collecting funds to support it. In annual “coronations,” girls we

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Ren, Jiangping, Zhengting Wang, and Enfu Chen. "Different Associations between DC-SIGN Promoter-336G/A (rs4804803) Polymorphism with Severe Dengue in Asians and South-Central Americans: a Meta-Analysis." International Journal of Environmental Research and Public Health 16, no. 8 (2019): 1475. http://dx.doi.org/10.3390/ijerph16081475.

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Objective: This study was conducted to identify the association between rs4804803 polymorphism in DC-SIGN with the susceptibility of severe dengue. Methods: A comprehensive search was conducted to identify all eligible papers in PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), and Google Scholar. Odds ratios (ORs) and corresponding 95% confidence intervals (95% CIs) were used to assess the association. Subgroup analyses were performed by ethnicity. Sensitivity analyses were performed through employing different statistical models (fixed versus random effect model). Resul

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Indares, Aphrodite, and Abdelali Moukhsil. "Geon 12 crustal extension in the central Grenville Province, implications for the orogenic architecture, and potential influence on the emplacement of anorthosites." Canadian Journal of Earth Sciences 50, no. 9 (2013): 955–66. http://dx.doi.org/10.1139/cjes-2012-0161.

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Remnants of a ca. 1.24 Ga old volcanic belt formed in a within-plate setting (Manicouagan Crustal Extension Belt) are exposed over several tens of kilometres in the hinterland of the central Grenville Province, and can be recognized despite granulite-facies Grenvillian metamorphism and deformation. This belt mainly consists of layered felsic–mafic rock units, some of which are documented here for the first time. In the vicinity of the 1.24 Ga belt, a Geon 14 arc-related mafic suite and a Geon 15 metasedimentary package were pervasively injected by felsic (and mafic) material, show evidence of

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Holmden, C., and A. P. Dickin. "Paleoproterozoic crustal history of the southwestern Grenville Province: evidence from Nd isotopic mapping." Canadian Journal of Earth Sciences 32, no. 4 (1995): 472–85. http://dx.doi.org/10.1139/e95-040.

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Nd isotopic mapping in the North Bay area of the Central Gneiss Belt, southwestern Grenville Province, has revealed the precise trend of a TDM model age line developed between the uplifted southern margin of the Archean Superior craton (TDM = 2.7 Ga) and a Paleoproterozoic allochthon (TDM = 1.9 Ga). Separating these two crustal blocks is a narrow zone of gneisses with intermediate TDM ages. These transitional gneisses are interpreted to reflect a remnant fault or ductile shear zone, of uncertain age, along which crustal material from both blocks mechanically mixed during their juxtaposition. A

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Valverde Cardenas, Carolina, Aphrodite Indares, and George Jenner. "Mafic and ultrapotassic rocks from the Canyon domain (central Grenville Province): geochemistry and tectonic implications." Canadian Journal of Earth Sciences 49, no. 2 (2012): 412–33. http://dx.doi.org/10.1139/e11-065.

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The Canyon domain and the Banded complex in the Manicouagan area of the Grenville Province preserve a record of magmatic activity from ∼1.4 to 1 Ga. This study focuses on 1.4–1.2 Ga mafic rocks and 1 Ga ultrapotassic dykes. Geochemistry and Sm–Nd isotopic signatures were used to constrain the origin of these rocks and evaluate the changing role of the mantle with time and tectonic setting from the late evolution of the Laurentian margin to the Grenvillian orogeny, in the Manicouagan area. The mafic rocks include layers inferred to represent flows, homogeneous bodies in mafic migmatite, and def

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Saxena, Hariom, N. D. Kobragade, Samiksha Parihar, M. Kundu, G. Rajeshwar Rao, and Ganesh Pawar. "Chemical and morphological variations in Terminalia bellirica (Gaertn.) Roxb. – a species of commercial ayurvedic formulation triphla from central India." Environment Conservation Journal 23, no. 1&2 (2022): 410–16. http://dx.doi.org/10.36953/ecj.0211162.2305.

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Terminalia bellirica is one of the high traded medicinal plant species, mainly known for its fruits which are bestowed with numerous biological activities and used in treatment of various ailments. The fruits are one of three ingredients of well-known Ayurvedic formulation ‘TRIPHLA’. The purpose of this study was to determine the variations for Gallic acid (GA), a chemical marker compound, as well as for key morphological traits (height, girth at breast height, clear bole height, fruit size) in trees from central Indian states viz. Madhya Pradesh, Chhattisgarh and Maharashtra. In this investig

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Liu, Chenyi, Hanfei Wu, Jimeng Lao, et al. "Measurement and Analysis of Central Corneal Thickness at Different Postnatal Stages in Chinese Premature Infants." Journal of Ophthalmology 2020 (September 16, 2020): 1–7. http://dx.doi.org/10.1155/2020/7313909.

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Purpose. The objective of this study was to evaluate central corneal thickness (CCT) in Chinese premature infants at different postnatal stages to study the peak point and analyze influential factors on CCT development. Methods. This was a cross-sectional study of premature infants. Initial CCT measurement was taken at 34 weeks of gestational age (GA) and at intervals until 88 weeks of postmenstrual age (PMA) was reached. The comparison and correlation analysis were carried out to access the association of CCT with gender, birth weight (BW), GA, and retinopathy of prematurity (ROP) for each PM

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Litvinenko, Andrey K., Elena S. Sorokina, Tobias Häger, et al. "Petrogenesis of the Snezhnoe Ruby Deposit, Central Pamir." Minerals 10, no. 5 (2020): 478. http://dx.doi.org/10.3390/min10050478.

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The Snezhnoe ruby deposit is located in the Muzkol–Rangkul anticlinorium within the Cimmerian zone of the Central Pamir. On the local scale, the deposit occurs on discrete relict bedding planes of calcitic marbles belonging to the Sarydzhilgin suite. Four ruby-bearing mineral assemblages are present within the main parts of the deposit: (1) scapolite + phlogopite + muscovite + margarite; (2) plagioclase + muscovite + margarite; (3) muscovite + phlogopite + margarite; (4) calcite. The ruby + calcite association is the most economically important, whereas the association of plagioclase + scapoli

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Zeng, Xi, Yangliuzi Hu, Shujuan Xiao, Ni-Ni Chen, Yang Zhou, and Miyang Luo. "Mediation effect of body mass index on the association between glycated albumin and 10-year atherosclerotic cardiovascular disease risk in Hunan residents of China: a retrospective cross-sectional study." BMJ Open 15, no. 5 (2025): e092714. https://doi.org/10.1136/bmjopen-2024-092714.

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ObjectivesGlycated albumin (GA) and body mass index (BMI) are associated with the risk of atherosclerotic cardiovascular disease (ASCVD). However, the role of BMI in the association between GA and 10-year ASCVD risk is still not fully understood.DesignA retrospective cross-sectional study.SettingIn this retrospective cross-sectional study, 4646 healthy subjects who received a full health examination at the Health Management Medical Center, Third Xiangya Hospital of Central South University, from 1 January 2022 to 30 December 2023 were initially identified. According to the exclusion criteria,

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Mortazavi, Abolghasem, Alirerza Jamali, Hassan Hashemi, Mohammadreza Aghamirsalim, and Mehdi Khabazkhoob. "Prevalence of retinal pathologies in people over 60 years: the Tehran Geriatrics Eye Study." International Journal of Ophthalmology 17, no. 4 (2024): 721–28. http://dx.doi.org/10.18240/ijo.2024.04.17.

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AIM: To determine the prevalence of some retinal pathologies in people over 60y and their association with demographic and ocular factors. METHODS: A cross-sectional study was conducted in Tehran using multistage cluster sampling. After selecting subjects aged 60 and over, optometric, and ophthalmic examinations were done. For retinal examination, a 90 D lens was used and indirect ophthalmoscopy was performed after instilling tropicamide drops. Biometry was done using the IOL Master for all participants. RESULTS: Of 3791 people that were invited through cluster sampling, 3310 participated in t

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Coviello, Caterina, Silvia Lori, Giovanna Bertini, et al. "Evaluation of the Relationship between Pain Exposure and Somatosensory Evoked Potentials in Preterm Infants: A Prospective Cohort Study." Children 11, no. 6 (2024): 676. http://dx.doi.org/10.3390/children11060676.

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Background and aim: First, to compare somatosensory evoked potentials (SEPs) in preterm newborns without major brain injury studied at term equivalent age (TEA) with a term historical control group. Second, to investigate the impact of pain exposure during the first 28 days after birth on SEPs. Third, to evaluate the association between SEPs and Bayley-III at 2 years corrected age (CA). Methods: Infants born at <32 weeks’ gestational age (GA) were studied with continuous-SEPs. First, SEP differences between preterm and term infants were analyzed. Second, regression analyses were conducted t

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Mikkola, Perttu, Maija Pietilä, Tapani Rämö, and Hannu Huhma. "1.88 Ga granitoids at Sorsakoski, Central Finland: A-type magmatism within the Raahe-Ladoga suture zone." Bulletin of the Geological Society of Finland 96, no. 1 (2024): 59–80. http://dx.doi.org/10.17741/bgsf/96.1.003.

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Four quartz monzonite – granite intrusions forming the Sorsakoski granite lithodeme, are found within the Raahe-Ladoga suture zone in Central Finland. The prevailing potassium feldspar megacrystic quartz monzonites and granites form a bimodal association with diorites and gabbros. The granitoids are mainly calc-alkaline, ferroan, per- to metaluminous, and have high Zr and REE contents. Dominant mafic minerals are biotite and hornblende, clinopyroxene and orthopyroxene are locally present. The mafic units display effects of fractionation of clinopyroxene. In our interpretation, these intrusions

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Razak, Abdul, and Maher Faden. "Association of small for gestational age with retinopathy of prematurity: a systematic review and meta-analysis." Archives of Disease in Childhood - Fetal and Neonatal Edition 105, no. 3 (2019): 270–78. http://dx.doi.org/10.1136/archdischild-2019-316976.

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ContextThe association between small for gestational age (SGA) and retinopathy of prematurity (ROP) is unclear.ObjectiveA systematic review and meta-analysis was conducted to evaluate the association between ROP and SGA in preterm infants <37 weeks’ gestational age (GA) admitted to neonatal intensive care unit.MethodsMedline, PubMed, Web of Science and Cochrane Central databases were searched from inception through 15 January 2019. Studies reporting outcomes based on SGA as the primary exposure variable were included. Data were extracted independently by two coauthors. Modified Newcastle-Ot

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Mir, Rashid, Musadiq Bhat, Jamsheed Javid, Chandan Jha, Alpana Saxena, and Shaheen Banu. "Potential Impact of COMT-rs4680 G > A Gene Polymorphism in Coronary Artery Disease." Journal of Cardiovascular Development and Disease 5, no. 3 (2018): 38. http://dx.doi.org/10.3390/jcdd5030038.

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Purpose: Catechol-O-methyltransferase (COMT) plays a central role in DNA repair and estrogen-induced carcinogenesis. The nonsynonymous single nucleotide polymorphism (SNP) in exon 4 G > A or Val108 > 158Met or rs4680 G > A influences COMT enzyme activity. The three phenotypes of the COMT enzyme activities include COMT A/A with low enzyme activity, COMT A/G with medium enzyme activity and COMT G/G with high enzyme activity. The Met allele is associated with low enzymatic activity resulting in higher levels of prefrontal dopamine. Conversely, the Val allele is associated with high enzym

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Bala, Laksha, Christie Tsang, Vani Agarwal, and Noha Elshimy. "BH16 Central centrifugal cicatricial alopecia and fibroproliferative disorders: exploring the association with uterine leiomyomas." British Journal of Dermatology 191, Supplement_1 (2024): i80. http://dx.doi.org/10.1093/bjd/ljae090.163.

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Abstract Central centrifugal cicatricial alopecia (CCCA) is a type of scarring alopecia, which typically starts on the crown and progresses in a centrifugal manner. It predominantly affects women of African descent and often has devastating psychosocial implications. The pathogenesis of CCCA is not fully understood and therapeutic options are limited. It has been proposed that CCCA is a fibroproliferative disorder (FPD) with persistent, low-grade inflammation resulting in end-stage fibrosis. People of African descent are at increased risk of FPDs including uterine leiomyomas (ULs), possibly du

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Necchi, Andrea, Roger Li, Kyle M. Rose, et al. "CDH1-mutated clinically advanced urothelial bladder cancer (UBC): A genomic landscape and real-world clinical outcome study (RWCOS)." Journal of Clinical Oncology 41, no. 6_suppl (2023): 564. http://dx.doi.org/10.1200/jco.2023.41.6_suppl.564.

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564 Background: CDH1 mutated UBCs are characterized by plasmacytoid histology and are associated with an aggressive clinical course at the time of diagnosis. Methods: Cohort 1: 6,676 clinically advanced UBC patients (pts) underwent comprehensive genomic profiling (CGP) to evaluate all classes of genomic alterations (GA), microsatellite instability (MSI), tumor mutational burden (TMB), and genomic loss of heterozygosity (gLOH, high ≥16%). Predominant genetic ancestry was determined using a SNP-based approach and classified as one of the 5 categories: African (AFR), European (EUR), Central and S

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Zhou, Li, Cheng Luo, Jiawei Yin, et al. "Diverse Associations of Plasma Selenium Concentrations and SELENOP Gene Polymorphism with Metabolic Syndrome and Its Components." Oxidative Medicine and Cellular Longevity 2020 (April 23, 2020): 1–11. http://dx.doi.org/10.1155/2020/5343014.

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The relationship between selenium and metabolic syndrome (MetS) has been discussed controversially, and limited studies have examined the associations of single nucleotide polymorphisms in selenoproteins genes with MetS. Hence, to examine the associations of plasma selenium concentrations and selenoprotein P rs7579 polymorphism with MetS, a case-control study of 1279 MetS cases and 1279 sex- and age- (±2 years) matched controls was conducted based on the baseline data of the Tongji-Ezhou Cohort study. Plasma selenium concentrations were measured by inductively coupled plasma mass spectrometry.

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Zhu, Jinhong, Xiaoping Liu, Wei Chen, et al. "Association of RNA m7G Modification Gene Polymorphisms with Pediatric Glioma Risk." BioMed Research International 2023 (January 24, 2023): 1–10. http://dx.doi.org/10.1155/2023/3678327.

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Glioma stemming from glial cells of the central nervous system (CNS) is one of the leading causes of cancer death in childhood. The genetic predisposition of glioma is not fully understood. METTL1-WDR4 methyltransferase complex is implicated in tumorigenesis by catalyzing N7-methylguanosine (m7G) modification of RNA. This study is aimed at determining the association of glioma risk with three polymorphisms (rs2291617, rs10877013, and rs10877012) in METTL1 and five polymorphisms (rs2156315 rs2156316, rs6586250, rs15736, and rs2248490) in WDR4 gene in children of Chinese Han. We enrolled 314 cas

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Artemenko, G. V., and L. V. Shumlyanskyy. "THE PALEOARCHEAN (3.3 Ga) AND MESOARCHEAN (3.0 Ga) TTGs OF THE WESTERN AZOV AREA, THE UKRAINIAN SHIELD." Geological Journal, no. 3 (October 8, 2021): 35–47. http://dx.doi.org/10.30836/igs.1025-6814.2021.3.228873.

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A large anticline structure that includes the West Azov and Remivka blocks occurs in the western part of the Azov Domain of the Ukrainian Shield. These blocks are composed of rocks of the Mesoarchean (3.2-3.0 Ga) granite-greenstone association and relics of an older basement. The anticline is divided into two parts by the Bilotserkivka structure of sub-latitudinal strike; the northern part includes the Huliaipole and Remivka blocks, and the southern part is comprised of the Saltycha anticline. The Archean plagiogranitoids of the West Azov underwent intense dislocation metamorphism during the P

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Choubey, Mayank, and Puran Bora. "Emerging Role of Adiponectin/AdipoRs Signaling in Choroidal Neovascularization, Age-Related Macular Degeneration, and Diabetic Retinopathy." Biomolecules 13, no. 6 (2023): 982. http://dx.doi.org/10.3390/biom13060982.

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Age-related macular degeneration (AMD), a leading cause of irreversible blindness in adults, may result in poor central vision, making it difficult to see, read, and drive. AMD is generally classified in either dry or wet types. Milder cases of dry AMD may progress to geographic atrophy (GA), leading to significant visual disability; wet, or neovascular AMD, which involves choroidal neovascularization (CNV), can lead to complete loss of central vision. Adiponectin (APN) discovery in the mid-1990’s and, subsequently, its two cognate receptors (AdipoRs) in the early 2000s have led to a remarkabl

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Elton, G. R. "English Religion 1500–1540. A bibliography. Edited by Donald Dean Smeeton. (National Association of Baptist Professors of Religion. Bibliographic Series, 2.) Pp. xiii + 114. Macon, GA: Mercer University Press, 1989. $16.95. 0 86554 325 9." Journal of Ecclesiastical History 41, no. 1 (1990): 161. http://dx.doi.org/10.1017/s002204690007411x.

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Baldwin, Elizabeth, Jan Narciso, Randy Cameron, and Anne Plotto. "(193) Effect of Pectin Oligomers on Strawberry Fruit Decay and Ethylene Production." HortScience 41, no. 4 (2006): 1044B—1044. http://dx.doi.org/10.21273/hortsci.41.4.1044b.

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Strawberry fruit were harvested on three different dates from the Strawberry Association plot (cv. Festival), a commercial farm (cv. Camino Real), and at the University of Florida Gulf Coast Research and Education Center (cv. Sweet Charlie), in central Florida in 2005 and 2006. Fruit were transported to the USCSPL in Winter Haven, Fla., sorted, dipped for 10 s in treatment solutions, drained and stored in commercial clam-shells at 15 to 19 °C. Percentage of decay (number of fruit with lesions) was monitored during storage. There were 10 fruit per replicate clamshell, and three to four replicat

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Pal, Sumanta K., Daniel M. Geynisman, Siraj Mahamed Ali, et al. "Comprehensive genomic profiling (CGP) of advanced papillary renal cell carcinoma (PRCC) to reveal distinctions from TCGA dataset." Journal of Clinical Oncology 35, no. 15_suppl (2017): 4517. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.4517.

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4517 Background: Biologic characterization of PRCC by TCGA reveals alterations in MET in type 1 disease, and CDKN2Asilencing, SETD2 mutations and TFE3 fusions in type 2 disease. A limitation of TCGA data is that of 161 pts analyzed, 73% and 3% had M0 and M1 disease, respectively. We present the gene alterations (GA) identified in pts with advanced PRCC.Methods: FFPE tissue was obtained from 169 patients with PRCC. Diagnosis and PRCC subtyping was centrally confirmed by 2 board-certified pathologists. DNA was extracted and comprehensive genomic profiling (CGP) was performed (median coverage, 64

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Severson, Eric Allan, Shakti Ramkissoon, Sugganth Daniel, et al. "Association of tumor mutational burden in cutaneous squamous cell carcinoma with genomic alterations in Notch family receptors." Journal of Clinical Oncology 35, no. 15_suppl (2017): e13031-e13031. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.e13031.

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e13031 Background: In Cutaneous Squamous Cell Carcinoma (cSqCC), Notch1, Notch2, and Notch3 have been identified as tumor suppressors with a high rate of inactivating mutations early in cSqCC pathogenesis. Despite the high frequency of alterations, the biologic and therapeutic implications of Notch genomic alterations (GAs) in cSqCC are incompletely understood. Methods: 232 FFPE samples of cSqCC were evaluated by comprehensive genomic profiling (CGP) of 315 genes and analyzed for all classes of GAs, with diagnoses confirmed by central pathology review. Notch GAs with unknown functional impact

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Duong, Quang Huy, Quang Nhut Le, and Xuan Kien Nguyen. "STUDY ON STAT6 rs324015 POLYMORPHISM IN HEPATITIS B VIRUS-RELATED HEPATOCELLULAR CARCINOMA PATIENTS." VietNam Military Medical Unisversity 49, no. 4 (2024): 33–42. http://dx.doi.org/10.56535/jmpm.v49i4.573.

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Objectives: To determine the genotype frequency of the STAT6 rs324015 polymorphism and its association with cancer risk in hepatitis B virus (HBV) -related hepatocellular carcinoma (HCC) patients. Methods: A cross-sectional descriptive study on 118 HBV-related HCC patients, compared to 86 HBV-related cirrhosis patients and 195 healthy people at 108 Military Central Hospital, Military Hospital 103, and Can Tho General Hospital from July 2017 to August 2020. Polymorphism analysis of the STAT6 rs324015 gene was conducted from peripheral blood samples of subjects using the Sanger sequencing method

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Beltempo, Marc, Robert Platt, Anne-Sophie Julien, et al. "67 Are NICUs too busy?" Paediatrics & Child Health 26, Supplement_1 (2021): e47-e48. http://dx.doi.org/10.1093/pch/pxab061.052.

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Abstract Primary Subject area Neonatal-Perinatal Medicine Background In a health care system with limited resources, hospital organizational factors such as unit occupancy and nurse-to-patient ratios may contribute to patient outcomes. Objectives We aimed to assess the association of NICU occupancy and nurse staffing with outcomes of very preterm infants born &lt; 33 weeks gestational age (GA). Design/Methods This was a multicenter retrospective cohort study of infants born 23-32 weeks GA without major congenital anomaly, admitted within 2 days after birth to one of four Level 3 NICUs in Q

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Wang, Yijun, Gang Chen, Qingyun Tu, et al. "Associations between Aquaglyceroporin Gene Polymorphisms and Risk of Type 2 Diabetes Mellitus." BioMed Research International 2018 (November 27, 2018): 1–7. http://dx.doi.org/10.1155/2018/8167538.

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Objectives. AQP7 and AQP9 represent glycerol channel in adipose tissue and liver and have been associated with metabolic diseases. We aimed to investigate the associations between genetic variants in AQP7 and AQP9 genes and the risk of type 2 diabetes (T2DM) in Chinese population. Methods. Blood samples were drawn from 400 T2DM patients and 400 age- and gender-matched controls. Genomic DNA was extracted by proteinase K digestion and phenol–chloroform extraction. Genotyping of 5 single nucleotide polymorphisms (SNPs) in AQP7 (rs2989924, rs3758269, and rs62542743) and AQP9 (rs57139208, rs1693988

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Vaknin-Dembinsky, Adi, Livnat Brill, Naama Orpaz, Oded Abramsky, and Dimitrios Karussis. "Preferential increase of B-cell activating factor in the cerebrospinal fluid of neuromyelitis optica in a white population." Multiple Sclerosis Journal 16, no. 12 (2010): 1453–57. http://dx.doi.org/10.1177/1352458510380416.

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Background: Anti-aquaporin-4 antibodies are believed to have a central pathogenetic role in neuromyelitis optica (NMO). B-cell activating factor (BAFF) is one of the crucial factors that determines the fate and survival of B cells and may play a role in induction of antibody-mediated autoimmunity. Objectives: To evaluate the blood and cerebrospinal fluid (CSF) levels of BAFF in NMO and multiple sclerosis (MS) patients. Methods: Peripheral blood samples were collected from 21 definite NMO patients, 22 healthy controls and 45 MS patients and CSF from 8 NMO and 11 MS patients. BAFF levels were me

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Basin, Michael, Joseph M. Jacob, Gennady Bratslavsky, et al. "Extracellular domain ERBB2 (ERBB2 ECD+) mutations in urothelial bladder cancer (UBC)." Journal of Clinical Oncology 41, no. 6_suppl (2023): 566. http://dx.doi.org/10.1200/jco.2023.41.6_suppl.566.

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566 Background: Given the recent approval in lung cancer for the first anti-HER2 targeted therapy directed against activating kinase domain exon 20 ERBB2 insertion mutations, considerable interest has arisen in targeting additional locations in the ERBB2 gene in other tumor types. Methods: 5,485 UBC samples were sequenced using a hybrid capture-based comprehensive genomic profiling (CGP) assay to assess all classes of genomic alterations (GA), tumor mutational burden (TMB), microsatellite instability (MSI), genomic loss of heterozygosity (gLOH), trinucleotide signatures and predominant genetic

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Padula, M. C., P. Leccese, N. Lascaro та ін. "AB0018 TNFΑ RS1800629 POLYMORPHISM: WHAT ABOUT ITS ASSOCIATION WITH CLINICAL MANIFESTATIONS AND ANTI-TNFΑ THERAPY? DATA FROM A SERIES OF ITALIAN PATIENTS WITH BEHÇET SYNDROME". Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1312.1–1312. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2295.

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Background:Tumor Necrosis Factor-alpha (TNF-α) is a pleiotropic cytokine with a critical role in the pathogenesis of Behçet syndrome (BS). Anti-TNF-α therapy is useful for patients with refractory, severe BS, in particular for ocular, central nervous system, and gastrointestinal manifestations. However, although biological treatment with anti-TNF-α agents are effective in BS, not all patients are definite responders. Non-responders patterns could be due to: alternative non-TNFα related pathway of inflammation; anti-drug antibodies presence or development; polymorphic alleles ofTNFαgene.TNFαrs1

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Shehzad, Muhammad Irfan, Anwar Ul Haq, Ikram Zada, Muhammad Adnan Shahid, Noman Kareem Qureshi, and Shah Bakht Azeem. "A Cross-Sectional Study on Association between Metabolic Syndrome and Hepatobiliary Cancers." Pakistan Journal of Medical and Health Sciences 17, no. 1 (2023): 339–42. http://dx.doi.org/10.53350/pjmhs2023171339.

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Background and Aim: Several studies have supported the idea that a metabolic abnormality contributes to expansion of hepatocellular carcinoma (HCC). To date, metabolic factors have not been shown to be associated with hepatocellular carcinoma (HCC). Therefore, the present study aimed to assess the metabolic syndrome association with hepatocellular carcinoma. Patients and Methods: This cross-sectional study was carried out on surgically treated and radiologically confirmed 360 HCC cases in Gastroenterology Department of Central Hospital, Sargodha and Hayatabad Medical Complex Peshawar, during t

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Zhu, Qi, Kun Xue, Hong Wei Guo, Fei Fei Deng, and Yu Huan Yang. "Interaction of the CMTM7 rs347134 Polymorphism with Dietary Patterns and the Risk of Obesity in Han Chinese Male Children." International Journal of Environmental Research and Public Health 17, no. 5 (2020): 1515. http://dx.doi.org/10.3390/ijerph17051515.

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A genome-wide association study (GWAS) in the Han Chinese population had found that single nucleotide polymorphism (SNP) on the CMTM7 gene rs347134 was significantly associated with Body Mass Index (BMI). In the present study, the association of the rs347134 SNP with obesity and its interaction with dietary patterns (DPs) were explored in Han Chinese children. This cross-sectional study group included 1292 children, in whom obesity-related indicators were evaluated, the rs347134 SNP was genotyped by improved Multiple Ligase Detection Reaction (iMLDR), and the DPs were identified by principal c

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C.S, Ngozi-Chika, Olorunyomi A. E., Echetema H. N., and Ibrahim O.I. "Factor analyses of transformed geochemical compositional data of meme river stream sediment, Lokoja, north central Nigeria." International Journal of Advanced Geosciences 9, no. 1 (2021): 19. http://dx.doi.org/10.14419/ijag.v9i1.31332.

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Geochemical mapping using stream sediments from MRDB, north-central, Nigeria was undertaken towards obtaining multivariate association patterns reflecting the presence of ore mineralization in Lokoja region. The area is underlain by Precambrian crystalline rocks within the Benin-Nigeria Shield and clastic sedimentary rocks of Bida Basin (one of Nigeria inland sedimentary basins). The basement crystalline rocks have been known as a source of ore minerals in Nigeria. The major lithological units are cut by the Meme river watershed which have deposited in their tributaries, large quantities of al

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Nadeau, Léopold, and Otto van Breemen. "Plutonic ages and tectonic setting of the Algonquin and Muskoka allochthons, Central Gneiss Belt, Grenville Province, Ontario." Canadian Journal of Earth Sciences 35, no. 12 (1998): 1423–38. http://dx.doi.org/10.1139/e98-077.

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The Central Gneiss Belt comprises parautochthonous gneisses overlain by northwest-transported allochthonous terranes originating from the pre-Grenvillian Laurentian margin or from farther outboard as inferred for the Parry Sound allochthon. In the Huntsville region, orthogneisses of the Algonquin allochthon yielded U-Pb zircon igneous crystallization ages at 1444 +12-8, 1442 +9-8, and 1432 +54-98 Ma. In absence of direct evidence for older intrusions, the association of these plutonic rocks with gneisses giving Nd crustal residence ages of ca. 1.7 Ga sets the Algonquin allochthon apart from th

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Pilitsyn, A. G., A. V. Volkov, and T. A. Pilitsyna. "Geochemical Features of the Kyplatap Ag-Au Ore Occurrence in Central Chukotka." Arctic: Ecology and Economy 13, no. 1 (2023): 34–50. http://dx.doi.org/10.25283/2223-4594-2023-1-34-50.

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The article considers the geochemical features of unconventional mineralization in secondary quartzite’s of the Kyplatap ore occurrence, located on the southeastern flank of the volcanic dome structure (VDS) of the same name, complicating the Palyavaam-Pykarvaam volcanotectonic depression (VTD) in the Chaun zone of the Central Chukotka sector of the Okhotsk-Chukotka volcanic Belt (OChVB). The Kyplatap VDS was formed due to the intrusion into the Late Cretaceous Alkaquun volcanites of a large laccolith-like subvolcanic body composed of rhyolite-trachyriolite-trachydacites. Based on the geochemi

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Acevedo-Godoy, M., S. J. Perdomo, W. Bautista-Molano, et al. "POS0137 FREQUENCIES OF WNT PATHWAY GENE VARIANTS ASSOCIATED WITH ANTI CARBAMYLATE PROTEIN IN EARLY RHEUMATOID ARTHRITIS." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 295.2–296. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4219.

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BackgroundIncreased bone resorption and impaired bone formation characterize the pathogenesis of rheumatoid arthritis (RA). Wnt/β-catenin pathway regulates osteoblast function. Since bone mineral density (BMD) and RA joint destruction are partially inherited, we studied the association of Dickkopf-1 (DKK-1), sclerostin (SOST), Kremen-1 and lipoprotein receptor-related protein-5 (LRP-5) genes single nucleotide polymorphisms (SNPs).ObjectivesTo establish the genotypic frequency of variants of the DKK-1 (rs1896368, rs1896367, rs1528873), SOST (rs6503475), Kremen-1 (rs132274) and LRP-5 (3736228) g

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Moskalenko, M. I., I. V. Ponomarenko, A. V. Polonikov, and M. I. Churnosov. "Polymorphic locus rs652438 of the MMP12 gene is associated with the development of hypertension in women." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 25, no. 1 (2019): 60–65. http://dx.doi.org/10.18705/1607-419x-2019-25-1-60-65.

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Objective.To study the association of polymorphic loci rs243865 MMP2, rs17577 MMP9, rs652438 MMP12 with the development of arterial hypertension (HTN) in women of the Central Chernozem Region of Russia.Design and methods.A total of 584 women were examined: 375 HTN patients and 209 controls. Analysis of the polymorphic loci of metallоproteinases was performed using real-time polymerase-chain reaction (PСR). Statistical analysis was carried оut using software “STATISTICA for Windows 10.0”. The prediсtive value of the non-synоnymous single nucleotide polymorphism (SNP) wаs estimatеd using the Sor

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Greere, Daniela, Sara Haydar, Florin Grigorescu, et al. "Fine-Scale Haplotype Mapping Reveals an Association of the FTO Gene with Osteoporosis and Fracture Risk in Postmenopausal Women." Genes 15, no. 9 (2024): 1152. http://dx.doi.org/10.3390/genes15091152.

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Introduction. The Fat Mass and Obesity-Associated (FTO) gene encodes a demethylase, which modulates RNA N6-methyladenosine (m6A) and plays a regulatory role in adipocyte differentiation and the pathogenesis of human obesity. Methods. To understand the potential role of FTO in osteoporosis (OP), we investigated five single nucleotide variations (SNVs) in intron 1 (rs8057044, rs8050136, rs9939609, rs62033406, and rs9930506) of the FTO gene, and a missense SNV i.e., rs3736228 (A1330V), located in exon 18 of the LRP5 gene, in a cohort of postmenopausal women (n = 188) from Central Europe. Genotypi

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Tu, Rong-Hui, Qing-Jie Li, Zheng Huang, et al. "Novel Functional Role of Heat Shock Protein 90 in Mitochondrial Connexin 43-Mediated Hypoxic Postconditioning." Cellular Physiology and Biochemistry 44, no. 3 (2017): 982–97. http://dx.doi.org/10.1159/000485399.

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Background/Aims: Previous studies have shown that heat shock protein 90 (HSP90)-mediated mitochondrial import of connexin 43 (Cx43) is critical in preconditioning cardioprotection. The present study was designed to test whether postconditioning has the same effect as preconditioning in promoting Cx43 translocation to mitochondria and whether mitochondrial HSP90 modulates this effect. Methods: Cellular models of hypoxic postconditioning (HPC) from rat heart-derived H9c2 cells and neonatal rat cardiomyocytes were employed. The effects of HPC on cardiomyocytes apoptosis were examined by flow cyto

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Liao, Dehua, Shuangshuang Wang, Miaomiao Cui, Jinhui Liu, Aiqun Chen, and Guohua Xu. "Phytohormones Regulate the Development of Arbuscular Mycorrhizal Symbiosis." International Journal of Molecular Sciences 19, no. 10 (2018): 3146. http://dx.doi.org/10.3390/ijms19103146.

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Most terrestrial plants are able to form a root symbiosis with arbuscular mycorrhizal (AM) fungi for enhancing the assimilation of mineral nutrients. AM fungi are obligate symbionts that depend on host plants as their sole carbon source. Development of an AM association requires a continuous signal exchange between the two symbionts, which triggers coordinated differentiation of both partners, to enable their interaction within the root cells. The control of the AM symbiosis involves a finely-tuned process, and an increasing number of studies have pointed to a pivotal role of several phytohorm

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Northrup, C. J., C. Isachsen, and S. A. Bowring. "Field relations, U-Pb geochronology, and Sm-Nd isotope geochemistry of the Point Lake greenstone belt and adjacent gneisses, central Slave craton, N.W.T., Canada." Canadian Journal of Earth Sciences 36, no. 7 (1999): 1043–59. http://dx.doi.org/10.1139/e99-004.

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Data from the Point Lake area, central Slave craton, suggest an intimate tectonic and paleogeographic association between volcano-sedimentary supracrustal rocks and adjacent gneisses. Granite plutons and orthogneisses yield U-Pb zircon crystallization ages ranging from ca. 3230 to 2818 Ma. Numerous mafic dykes cut the gneisses, and two have been dated by U-Pb zircon geochronometry at 2673 ± 3 and 2690 ± 3 Ma, ages similar to those of volcanic rocks in the Point Lake greenstone belt. Although high-strain zones form the greenstone-gneiss in most places, a structural repetition of granite about 4

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Loewenstein, Anat, Usha Chakravarthy, and Francesco Bandello. "The 0.19 mg Fluocinolone Acetonide Intravitreal Implant – A Review on its Use in Diabetic Macular Oedema from the Association for Research in Vision and Ophthalmology Annual Meeting 2018." European Ophthalmic Review 12, no. 2 (2018): 88. http://dx.doi.org/10.17925/eor.2018.12.2.88.

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Diabetic macular oedema (DMO) is a complication of diabetic retinopathy and a leading cause of visual impairment in patients with diabetes. ILUVIEN® (Alimera Sciences Inc., Alpharetta, GA, USA) is an intravitreal implant of fluocinolone acetonide (FAc), which is indicated in Europe for the treatment of vision impairment associated with chronic DMO that is considered insufficiently responsive to available therapies. This article reviews the clinical effectiveness and safety of the FAc implant from real-world studies presented at the Association for Research in Vision and Ophthalmology (ARVO) 20

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Guerini, Franca Rosa, Cristina Agliardi, Elisabetta Bolognesi, et al. "Two Single Nucleotide Polymorphisms in the Purinergic Receptor P2X7 Gene Are Associated with Disease Severity in Multiple Sclerosis." International Journal of Molecular Sciences 23, no. 23 (2022): 15381. http://dx.doi.org/10.3390/ijms232315381.

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Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the central nervous system (CNS) that leads to progressive physical disability. Recent evidence has suggested that P2X7 receptor (P2X7R)-mediated purinergic signalling pathways play a role in MS-associated neuroinflammation, possibly contributing to disease pathogenesis. To evaluate possible associations between P2X7R polymorphisms and MS disease severity, we performed an association study of five non-synonymous SNPs coding variants of the P2X7R gene: rs1718119 Ala348Thr, rs2230911 Thr357Ser, rs2230912 Gln460Arg, rs3751143

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Knop, Stefan, Markus Guenther, Juergen Loeffler, et al. "Mutational Status in Genes of Folate Metabolism Is Associated with Toxicity of High-Dose Methotrexate in Patients with Immunocompetent Primary Central Nervous System Lymphoma." Blood 108, no. 11 (2006): 2580. http://dx.doi.org/10.1182/blood.v108.11.2580.2580.

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Abstract Background: Outcome of patients with immunocompetent primary central nervous system lymphoma (PCNSL) has improved since the introduction of high-dose (HD) methotrexate (MTX). However, treatment may be perturbed by considerable toxicity. Acute toxicity comprises hematologic, renal, hepatic, pulmonary events and mucositis while neurologic impairment is essentially restricted to long-term survivors. MTX acts via inhibition of 5,10-methylentetrahydrofolate reductase (MTHFR) as well as thymidylate synthase (TYMS) in target cells what eventually results in decreased DNA synthesis. Intracell

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Schafer, Elizabeth, Christopher J. Johnson, Fabio Moraes, Jingxuan Zhao, Xuesong Han, and Ahmedin Jemal. "Association of Medicaid expansion with five-year survival after cancer diagnosis." Journal of Clinical Oncology 43, no. 16_suppl (2025): 11006. https://doi.org/10.1200/jco.2025.43.16_suppl.11006.

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11006 Background: Medicaid expansion is associated with improvements in early detection, access to treatment, and increased 2-year cancer survival. However, the association between Medicaid expansion and longer-term survival outcomes in newly diagnosed cancer patients remains understudied. Methods: Patients aged 18-59 years newly diagnosed with first primary cancers in 2007-2008 and 2014-2015 living in 25 states (AZ, AR, CA, CO, CT, DE, HI, IL, IA, KY, MD, MI, MN, NV, NH, NJ, NM, NY, ND, OH, OR, RI, WA, WV) that expanded Medicaid in 2014 and 12 states (AL, FL, GA, MS, MO, NC, OK, SC, TN, TX, W

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Virtanen, Ville J., Henri M.A. Höytiä, Giada Iacono-Marziano, Shenghong Yang, Marko moilanen, and Tuomo Törmänen. "From the mantle source to the crustal sink: magmatic differentiation and sulfide saturation of the Paleoproterozoic komatiites of the Central Lapland Greenstone Belt, Finland." Contributions to Mineralogy and Petrology 179 (June 26, 2024): 73. https://doi.org/10.1007/s00410-024-02154-9.

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Paleoproterozoic (2.05 Ga) komatiites are widespread in the Central Lapland Greenstone Belt (CLGB), northern Finland. Close association with sulfur (S)-rich country rocksand spatiotemporal connection with the Cu-Ni(-PGE) deposits of Kevitsa and Sakatti make these komatiites interesting targets for sulfide deposit exploration. We provide whole-rock geochemical data from Sattasvaara komatiites and combine it with literature data to form a geochemical database for the CLGB komatiites. We construct a model for the komatiites from adiabatic melting of the mantle source to fractional&

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El-Dokouny, Hanaa A., Nasser M. Mahdy, Hany H. El Hadek, et al. "Origin of Amphibole-Biotite-Fluorite-Rich Enclaves from Gabal El-Ineigi Fluorite-Bearing Granite, Central Eastern Desert of Egypt: Insights into Fluoride–Calcium and Silicate Liquid Immiscibility." Minerals 13, no. 5 (2023): 670. http://dx.doi.org/10.3390/min13050670.

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Gabal El-Ineigi fluorite-bearing rare-metal granite with A-type affinity, located in the Central Eastern Desert of Egypt, is distinguished by its abundance of large fluorite-quartz veins and mafic enclaves. Plagioclase (labradorite to oligoclase), Mg-rich biotite, and Mg-rich hornblende are the main components of mafic enclaves, with significant amounts of fluorite as essential phases, and titanite and Fe-Ti oxides (Nb-free rutile and ilmenite-rutile solid solution) as the main accessories. These enclaves are monzodioritic in composition, Si-poor, and highly enriched in Ca, Fe, Mg, and F compa

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Zheng, Xixian, and Wenmei Liao. "Coupling coordination between agricultural carbon emission efficiency and food security in China: The spatial-temporal evolution and prediction." PLOS One 20, no. 7 (2025): e0325026. https://doi.org/10.1371/journal.pone.0325026.

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Addressing climate change and food insecurity is crucial for achieving the Sustainable Development Goals (SDGs), with the enhancement of Agricultural Carbon Emission Efficiency (ACEE) and the assurance of Food Security (FS) playing pivotal roles. This study conducts a comprehensive evaluation of the coordination between ACEE and FS across 31 Chinese provinces from 2007 to 2021. The methodology employs the Super Slack-Based Model (SBM) and the Entropy- Weighted Technique for Order Preference by Similarity to Ideal Solution (EW-TOPSIS) for ACEE and FS assessments, respectively, while utilizing t

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Hindemith, Marisa, Aphrodite Indares, and Stephen Piercey. "Hydrothermally altered volcanic rocks metamorphosed at granulite-facies conditions: an example from the Grenville Province." Canadian Journal of Earth Sciences 54, no. 6 (2017): 622–38. http://dx.doi.org/10.1139/cjes-2016-0146.

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A 1.2 Ga association of aluminous gneisses, garnetites, and white felsic gneisses of andesitic composition in the southern Manicouagan area (central Grenville Province) provides evidence consistent with protolith formation and hydrothermal alteration in a submarine volcanic environment. In addition to field relations, potential relics of quartz phenocrysts in the aluminous gneisses, revealed by SEM–MLA (scanning electron microscope with a mineral liberation analysis software) imaging, are consistent with a volcanic precursor. Moreover, in these rocks, aluminous nodules and seams of sillimanite

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Artemenko, G. V., S. A. Wilde, L. V. Shumlyanskyy, M. J. Whitehouse, and A. Yu Bekker. "THE U-Pb AGE AND Lu-Hf ISOTOPE SYSTEMATICS OF ZIRCON FROM THE HULIAIPOLE MET AVOLCANICS, THE AZOV DOMAIN OF THE UKRAINIAN SHIELD: EVIDENCE FOR THE PALEOARCHEAN-HADEAN CRUST." Geological Journal, no. 1 (April 16, 2021): 3–16. http://dx.doi.org/10.30836/igs.1025-6814.2021.1.216989.

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The Azov Domain occurs as a part of a larger Mesoarchean (3.2-3.0 Ga) craton, fragments of which are preserved in the eastern part of the Ukrainian Shield and as a block of the Kursk Magnetic Anomaly (KMA). In the Neoarchean-Palaeoproterozoic time, it was fragmented into several tectonic blocks: Vovcha, Remivka, Huliaipole, Bilotserkivka, and Saltych. The northern part of the Huliaipole Block is composed of tonalite-trondhjemite-granodiorite (TTG) rock association, that hosts the Kosivtsevo greenstone structure. It is composed of metamorphosed rocks of the jaspilite-komatiite-tholeiite associa

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