Relevant bibliographies by topics / Central NT

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Central NT'

Author: Grafiati
Published: 4 June 2021
Last updated: 13 February 2022

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Journal articles on the topic "Central NT"

1

Xing, L. P., C. Balaban, J. Seaton, J. Washington, and G. Kauffman. "Mesolimbic dopamine mediates gastric mucosal protection by central neurotensin." American Journal of Physiology-Gastrointestinal and Liver Physiology 260, no. 1 (January 1, 1991): G34—G38. http://dx.doi.org/10.1152/ajpgi.1991.260.1.g34.

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Bilateral microinjection (1.0 microliter/side) of neurotensin (NT; 0.3, 1.5, and 3.0 micrograms/side) into the nucleus accumbens (NACB) and ventral tegmental area (VTA) but not in substantia nigra and striatum reduced gastric mucosal injury produced by 2 h of cold-water restraint (CWR). The minimal effective dose for NT-induced protection was 10-100 times lower when administered directly into NACB than into the lateral ventricle. These effects were blocked by pretreatment with the dopamine (DA) receptor antagonist, haloperidol (Hal; 0.5 microgram/side) given directly into NACB. Injection of 6-hydroxydopamine into VTA depleted endogenous DA and inhibited gastric mucosal protection against CWR-induced injury afforded by NT pretreatment. NT, given into either VTA and NACB, inhibited pentagastrin-stimulated gastric acid secretion. These results suggest that VTA and NACB, which represent the mesolimbic DA system, are important locations for interaction between NT and DA receptors to produce gastric mucosal protection against CWR-induced injury.
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Zhang, L., P. C. Colony, J. H. Washington, J. F. Seaton, and G. L. Kauffman. "Central neurotensin affects rat gastric integrity, prostaglandin E2, and blood flow." American Journal of Physiology-Gastrointestinal and Liver Physiology 256, no. 1 (January 1, 1989): G226—G232. http://dx.doi.org/10.1152/ajpgi.1989.256.1.g226.

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The aim of this study is to define the effect(s) of centrally administered neurotensin (NT) on gastric mucosal integrity, prostaglandin E2 (PGE2) generation, and blood flow during stress induced by cold-water restraint (CWR) in rats. Intracerebroventricular (icv) NT reduced macroscopic and microscopic damage. The former effect was dose dependent and was totally blocked by indomethacin pretreatment. Gastric mucosal PGE2 increased 27 and 30% at 30 and 60 min, respectively, in nonrestrained rats given icv NT. PGE2 generation was reduced in control rats during CWR but was maintained in CWR rats treated with icv NT. Gastric mucosal blood flow (GMBF) was significantly reduced in control rats during CWR. Mucosal blood flow was maintained at nonrestraint levels in the presence of icv NT during CWR; however, this effect was abolished by parenteral indomethacin pretreatment. Similarly, intravenous 16,16-dimethyl-PGE2 (200 micrograms.kg-1.h-1) maintained GMBF of non-CWR levels as well as preventing the macroscopic damage normally associated with CWR. These data suggest a protective role for central NT on the gastric mucosa, mediated, at least in part, by PGE2 generation and gastric mucosal blood flow.
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3

Moussadek, R., R. Mrabet, R. Dahan, A. Zouahri, M. El Mourid, and E. Van Ranst. "Tillage System Affects Soil Organic Carbon Storage and Quality in Central Morocco." Applied and Environmental Soil Science 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/654796.

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Stabilizing or improving soil organic carbon content is essential for sustainable crop production under changing climate conditions. Therefore, soil organic carbon research is gaining momentum in the Mediterranean basin. Our objective is to quantify effects of no tillage (NT) and conventional tillage (CT) on soil organic carbon stock (SOCs) in three soil types (Vertisol, Cambisol, and Luvisol) within Central Morocco. Chemical analyses were used to determine how tillage affected various humic substances. Our results showed that, after 5 years, surface horizon (0–30 cm) SOC stocks varied between tillage systems and with soil type. The SOCs was significantly higher in NT compared to CT (10% more in Vertisol and 8% more in Cambisol), but no significant difference was observed in the Luvisol. Average SOCs within the 0–30 cm depth was 29.35 and 27.36 Mg ha−1under NT and CT, respectively. The highest SOCs (31.89 Mg ha−1) was found in Vertisols under NT. A comparison of humic substances showed that humic acids and humin were significantly higher under NT compared to CT, but fulvic acid concentrations were significantly lower. These studies confirm that NT does have beneficial effects on SOCs and quality in these soils.
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4

Takahashi, Momoko, and Jason Tait Sanchez. "Effects of Neurotrophin-3 on Intrinsic Neuronal Properties at a Central Auditory Structure." Neuroscience Insights 15 (January 2020): 263310552098044. http://dx.doi.org/10.1177/2633105520980442.

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Neurotrophins, a class of growth factor proteins that control neuronal proliferation, morphology, and apoptosis, are found ubiquitously throughout the nervous system. One particular neurotrophin (NT-3) and its cognate tyrosine receptor kinase (TrkC) have recently received attention as a possible therapeutic target for synaptopathic sensorineural hearing loss. Additionally, research shows that NT-3-TrkC signaling plays a role in establishing the sensory organization of frequency topology (ie, tonotopic order) in the cochlea of the peripheral inner ear. However, the neurotrophic effects of NT-3 on central auditory properties are unclear. In this study we examined whether NT-3-TrkC signaling affects the intrinsic electrophysiological properties at a first-order central auditory structure in chicken, known as nucleus magnocellularis (NM). Here, the expression pattern of specific neurotrophins is well known and tightly regulated. By using whole-cell patch-clamp electrophysiology, we show that NT-3 application to brainstem slices does not affect intrinsic properties of high-frequency neuronal regions but had robust effects for low-frequency neurons, altering voltage-dependent potassium functions, action potential repolarization kinetics, and passive membrane properties. We suggest that NT-3 may contribute to the precise establishment and organization of tonotopy in the central auditory pathway by playing a specialized role in regulating the development of intrinsic neuronal properties of low-frequency NM neurons.
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5

Walz, J., P. V. d. S. Magalhães, L. M. Giglio, A. B. Cunha, L. Stertz, G. Fries, A. Andreazza, and F. Kapczinski. "Increased Serum Neurotrophin-4/5 Levels in Bipolar Disorder." European Psychiatry 24, S1 (January 2009): 1. http://dx.doi.org/10.1016/s0924-9338(09)70792-8.

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Neurotrophins are central to several aspects of central nervous system function, and emerging evidence links these growth factors to mood disorders. The purpose of this study was to investigate serum neurotrophin-4/5 (NT-4/5) levels in patients with bipolar disorder, both within mood episodes and in euthymia. Patients with bipolar I disorder (n=154) and controls (n=30) had their NT-4/5 serum levels assayed using an ELISA. Levels of NT-4/5 levels were significantly higher in bipolar disorder patients than in controls; NT-4/5 levels were increased in mania, depression and euthymia, but not significantly different between BD mood states. As far as are aware, this is the first study showing NT-4/5 immunocontent alterations in bipolar disorder. A tentative explanation would be that NT-4/5 increases is compensating for ongoing oxidative damage in dopaminergic neurons.
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6

Seferian, Karina R., Natalia N. Tamm, Alexander G. Semenov, Anastasia A. Tolstaya, Ekaterina V. Koshkina, Mihail I. Krasnoselsky, Alexander B. Postnikov, et al. "Immunodetection of Glycosylated NT-proBNP Circulating in Human Blood." Clinical Chemistry 54, no. 5 (May 1, 2008): 866–73. http://dx.doi.org/10.1373/clinchem.2007.100040.

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Abstract Background: Brain natriuretic peptide (BNP) or NT-proBNP (N-terminal fragment of BNP precursor) measurements are recommended as aids in diagnosis and prognosis of patients with heart failure. Recently it has been shown that proBNP is O-glycosylated in human blood. The goal of this study was to map sites on the NT-proBNP molecule that should be recognized by antibodies used in optimal NT-proBNP assays. Methods: We analyzed endogenous NT-proBNP by several immunochemical methods using a broad panel of monoclonal antibodies specific to different epitopes of the NT-proBNP molecule. Results: Treatment of endogenous NT-proBNP by a mixture of glycosidases resulted in significant improvement of the interaction between deglycosylated NT-proBNP and monoclonal antibodies (MAbs) specific to the mid-fragment of the molecule. MAbs specific to the N- and C-terminal parts of NT-proBNP (epitopes 13–24 and 63–76) were able to recognize glycosylated and deglycosylated protein with similar efficiency. Conclusions: The central part of endogenous NT-proBNP is glycosylated, making it almost “invisible” for the antibodies specific to the mid-fragment of the molecule. Thus sandwich assays using even one antibody (poly- or monoclonal) specific to the central part of the molecule could underestimate the real concentration of endogenous NT-proBNP. MAbs specific to the N- and C-terminal parts of NT-proBNP (epitopes 13–24 and 63–76) are the best candidates to be used in an assay for optimal NT-proBNP immunodetection.
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Ala-Kopsala, Minna, Jarkko Magga, Keijo Peuhkurinen, Jaana Leipälä, Heikki Ruskoaho, Juhani Leppäluoto, and Olli Vuolteenaho. "Molecular Heterogeneity Has a Major Impact on the Measurement of Circulating N-Terminal Fragments of A- and B-Type Natriuretic Peptides." Clinical Chemistry 50, no. 9 (September 1, 2004): 1576–88. http://dx.doi.org/10.1373/clinchem.2004.032490.

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Abstract Background: The N-terminal fragments of A- and B-type natriuretic peptides (NT-proANP and NT-proBNP) are powerful markers of cardiac function. The current assays require refinement with regard to standardization with native calibrators and the ability to detect the actual circulating forms. Methods: The following peptides were prepared with recombinant methods: NT-proANP, NT-proBNP, proBNP1–108, and Tyr0-proBNP77–108. Fifteen peptides of 13–22 amino acids, spanning the sequences of NT-proANP and NT-proBNP, were prepared by solid-phase peptide synthesis. Two immunoassays for NT-proANP and four for NT-proBNP were set up, each with a different epitope specificity. The assays were applied for the measurement of NT-proANP and NT-proBNP in healthy individuals and in patients with acute myocardial infarction. The circulating molecular forms were analyzed by gel-filtration and reversed-phase HPLC. Results: According to the HPLC analyses, circulating NT-proANP consists mainly of the full-length peptide, with some degradation at both ends. In contrast, circulating NT-proBNP is very heterogeneous. Most immunoreactive NT-proBNP is significantly smaller in size than NT-proBNP1–76, with truncation at both termini. The smallest fragments can be detected by assays directed at the central part of NT-proBNP only; assays directed at the ends gave 30–40% lower values. Despite the difference, the various assays correlated reasonably well with each other (r2 = 0.77–0.85). In patients with acute myocardial infarction, NT-proANP and NT-proBNP concentrations were 1.8–2.3 and 4.2–4.5 times higher than in healthy individuals. The development of heart failure further increased the concentrations. Conclusions: Molecular heterogeneity of the circulating forms causes a serious risk of preanalytical errors in assays for NT-proBNP and, to a lesser extent, NT-proANP. The development of a sandwich assay for NT-proBNP would be especially challenging. The most robust and reliable assays use antibodies directed at the central portions of NT-proANP or NT-proBNP.
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8

Webb, William J. "The Limits of a Redemptive-Movement Hermeneutic: A Focused Response to T. R. Schreiner." Evangelical Quarterly 75, no. 4 (April 16, 2003): 327–42. http://dx.doi.org/10.1163/27725472-07504003.

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Should one take the redemptive spirit within the slavery texts and the women texts beyond certain time-locked components of the NT? Does the redemptive movement, begun in the OT and extended in the NT, need to be extended even further beyond the NT? Or, should we expect the NT to express a totally realized ethic or a completely finalized expression of redemptive-movement meaning in all of its concrete particulars? Thomas R. Schreiner’s critique of the book, Slaves, Women and Homosexuals: Exploring the Hermeneutics of Cultural Analysis levels a central criticism against a redemptive-movement hermeneutic (RM hermeneutic), namely, that it fails to rightly appreciate the NT as God’s final and definitive revelation. Schreiner’s central criticism expresses his conviction about limiting the Christian use of a RM hermeneutic to the OT only; a RM hermeneutic ought not to be applied to the NT. In reply to Schreiner, this article attempts to correct a fundamental misunderstanding in the debate as well as to argue the alternative thesis that indeed a RM hermeneutic ought to be applied to the NT.
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9

Galal Zaky, Adel, Amin Faisal Ellakwa, and Ahmed Ibrahim Basiony. "Biomechanical Properties in Different Types of Thin Corneas in Menoufia Population." Journal of Ophthalmology 2021 (January 2, 2021): 1–12. http://dx.doi.org/10.1155/2021/6613143.

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Background. To evaluate and compare corneal hysteresis (CH) and corneal resistance factor (CRF) in normal thin (NT) healthy corneas with central corneal thickness (CCT) of 470–500 μm with matched thickness in keratoconus suspect (KCS) and keratoconus (KC) eyes. Methods. A total of 103 eyes in three groups were included prospectively: NT, KCS, and KC groups based on clinical examination and Pentacam findings. Corneal hysteresis (CH) and corneal resistance factor (CRF) were measured using the ocular response analyzer (ORA). CCT, CH, and CRF were compared between the three groups and statistically analyzed by variance tests. Results. The three groups consisted of 44 NT, 26 KCS, and 33 KC. The mean CH measured was 8.689 ± 1.775, 9.051 ± 1.1190, and 8.129 ± 0.8539 mmHg in NT, KCS, and KC eyes, respectively. The mean CRF was 8.441 ± 1.663, 8.337 ± 1.114, and 7.2422 ± 1.3110 mmHg in NT, KCS, and KC eyes, respectively. Within the range of central corneal thickness (470–500 μm), only mean CRF was statistically significantly different between the NT and KC ( P < 0.05 ); there was no statistically significant difference between NT and KCS, nor was the mean CH between each group ( P > 0.05 ). Conclusions. CRF only can be helpful in differentiating KC from NT eyes; KCS could not be predicted with either corneal biomechanical metrics. There was no benefit from CH in differentiating between the three study groups.
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10

Baldé, Alpha Bocar, Eric Scopel, François Affholder, Fernando Antonio Macena Da Silva, Jacques Wery, and Marc Corbeels. "Maize relay intercropping with fodder crops for small-scale farmers in central Brazil." Experimental Agriculture 56, no. 4 (July 17, 2020): 561–73. http://dx.doi.org/10.1017/s0014479720000150.

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AbstractRelay intercropping of maize with fodder crops is a promising option for sustainable intensification of dairy small-scale farms in the Cerrado of Brazil. Twenty-six intercropping trials were conducted on farmers’ fields with the following experimental treatments: sole maize crop cropping (MS), maize-Brachiaria intercropping (MB) and maize-pigeon pea intercropping (MP). The trials were managed by the farmers, i.e. choice of conventional tillage (CT) versus no-tillage (NT), sowing dates, fertilization and weed control. Maize grain yield varied strongly across the farmer fields, from 100 to 5900 kg ha−1 in the MS treatment, 500 to 6900 kg ha−1 in MP and 300 to 5500 kg ha−1 in MB. Intercropping did not significantly affect maize grain yields under NT, but yields were reduced under CT in one out of two seasons. Maize yields in the intercropped systems were also higher under NT than CT. Total biomass productivity was significantly higher in the maize-fodder than in the sole maize system. An increased interval between sowing of maize and fodder crop significantly reduced the fodder crop biomass. Relay intercropping, especially in combination with NT, is a promising option if crop calendars and fertilization are properly managed by farmers to reduce interspecific competition between the maize and fodder crop.
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Dissertations / Theses on the topic "Central NT"

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Girard, Christelle. "Stratégie intégrée pour la remyélinisation du système nerveux central : effet thérapeutique de la greffe de cellules de Schwann de primate surexprimant NT-3 et BDNF dans la moelle épinière démyélinisée de souris." Paris 6, 2005. http://www.theses.fr/2005PA066140.

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Books on the topic "Central NT"

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Masuzawa, Tomoko. In search of dreamtime: The quest for the origin of religion. Chicago: University of Chicago Press, 1993.

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Cultural landscapes and environmental change. London: Arnold, 2000.

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Grabosky, Peter N. Wayward governance: Illegality and its control in the public sector. [Australia]: Australian Institute of Criminology, 1989.

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(Firm), Custom Cartographics. Canada national highwaymap: Including Calgary, AB, Charlottetown, PE, Edmonton, AB ... Yellowknife, NT : Featuring south central Canada, city to city mileage chart. UniversalMAP, 2000.

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Grabosky, Peter N. Wayward Governance: Illegality and Its Control in the Public Sector (Australian Studies in Law, Crime, and Justice). Natl Gallery of Australia, 1990.

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Book chapters on the topic "Central NT"

1

Mueller, Christian. "Chronic heart failure diagnosis: biomarkers." In ESC CardioMed, 1778–81. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0409.

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Natriuretic peptides including B-type natriuretic peptide (BNP), N-terminal (NT)-proBNP, and midregional pro-atrial natriuretic peptide (MR-proANP) are the biomarkers of choice in the diagnosis of heart failure. Assays measuring either BNP, NT-proBNP, or MR-proANP are widely available and run on large analysers operating in the central laboratory or as point-of-care options. Natriuretic peptides are considered quantitative markers of haemodynamic cardiac stress and therefore quantitative markers of heart failure itself. The clinical introduction of natriuretic peptides constitutes the most important advance in the diagnosis of heart failure in the last decade.
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Mueller, Christian. "Chronic heart failure diagnosis: biomarkers." In ESC CardioMed, 1778–81. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0409_update_001.

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Natriuretic peptides including B-type natriuretic peptide (BNP), N-terminal (NT)-proBNP, and midregional pro-atrial natriuretic peptide (MR-proANP) are the biomarkers of choice in the diagnosis of heart failure. Assays measuring either BNP, NT-proBNP, or MR-proANP are widely available and run on large analysers operating in the central laboratory or as point-of-care options. Natriuretic peptides are considered quantitative markers of haemodynamic cardiac stress and therefore quantitative markers of heart failure itself. The clinical introduction of natriuretic peptides constitutes the most important advance in the diagnosis of heart failure in the last decade.
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3

Mueller, Christian. "Chronic heart failure diagnosis: biomarkers." In ESC CardioMed, 1778–81. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0409_update_002.

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Natriuretic peptides including B-type natriuretic peptide (BNP), N-terminal (NT)-proBNP, and midregional pro-atrial natriuretic peptide (MR-proANP) are the biomarkers of choice in the diagnosis of heart failure. Assays measuring either BNP, NT-proBNP, or MR-proANP are widely available and run on large analysers operating in the central laboratory or as point-of-care options. Natriuretic peptides are considered quantitative markers of haemodynamic cardiac stress and therefore quantitative markers of heart failure itself. The clinical introduction of natriuretic peptides constitutes the most important advance in the diagnosis of heart failure in the last decade.
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4

Regev, Eyal. "Introduction." In The Temple in Early Christianity, 1–17. Yale University Press, 2019. http://dx.doi.org/10.12987/yale/9780300197884.003.0001.

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This introductory chapter provides an overview of the importance of the Temple for the early Christians and the diversity in the attitude toward the Temple found in the New Testament (NT). The Temple is the heart of ancient Judaism, in both an institutional and a symbolic sense. Meanwhile, early Christian discourse about the Temple engages with Judaism or with early Christianity's own Jewishness. This discourse is laden with deep religious sentiments, both positive and negative. Most NT texts allude to the Temple at a time when the physical structure is no longer in existence, and yet the Temple remains significant and even central to the authors of Luke, Hebrews, and Revelation. It is commonly argued that there are at least four ways in which the Temple is superseded in the NT texts: the church is the new Temple; the individual believer is the Temple; the Temple is in heaven; and the Temple is Jesus's body.
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Fehr, Hans, and Fabian Kindermann. "The overlapping generations model." In Introduction to Computational Economics Using Fortran. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198804390.003.0010.

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In discussing the life-cycle model, we focused on the individual-choice problem without taking into account the interaction between households, the production sector of the economy, and the government. In this chapter we take a broader perspective and embed the life-cycle model into a general equilibrium framework. In this framework, prices adjust in order to balance supply and demand in goods and factor markets and the government has to operate under some balanced-budget rules.As in the previous chapter, individuals save in order to smooth consumption over the life cycle. However now, individual savings behaviour endogenously determines the capital stock. This is the central difference from the static general equilibrium model discussed in Chapter 3. Since in our equilibrium framework we have to distinguish households within a given period according to their age or birth year, the models we study are called overlapping generations (OLG) models. In this chapter we introduce the most basic version of the OLG model and discuss the computation of a transition path and the intergenerational welfare effects of policy reforms. In Chapter 7 we extend this baseline model version in various directions. This subsection sketches the economic environment used in this chapter and Chapter 7. We describe the lifetime of people who inhabit the economy as well as their consumption decisions. Then we move on to the production side and the government structure. Finally, the equilibrium conditions for goods and factor markets which close the model are derived. Demographics As in Chapter 5 we assume that households in the model live for three periods. For simplicity we do not account for income and lifespan uncertainty. However, now in each successive period t a new cohort is born, where the number of households Nt in this cohort grows at a rate np,t, i.e. Nt = (1 + np,t)Nt−1. From Figure 6.1 one can understand why this demographic structure is called ‘overlapping generations’. In each period t a cohort Nt is born, but this ‘new’ cohort overlaps with the two cohorts Nt−1 and Nt−2 born in the previous two periods.
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Conference papers on the topic "Central NT"

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Liddicoat, Robert, and Jeffrey Janvier. "Casing and Inserted Pipe Inspection Program on the San Francisco Peninsula Using Robotic ILI." In 2016 11th International Pipeline Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/ipc2016-64586.

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Pacific Gas & Electric Company (PG&E) operates multiple gas transmission pipelines on the San Francisco Peninsula, a significant portion of which operate at low Maximum Allowable Operating Pressure (MAOP), typically below 300 psig and are challenging to inspect using traditional ILI technology. This paper describes PG&E’s use of Non-Traditional robotic ILI technology to inspect numerous cased pipelines located in High Consequence Areas in the highly populated and dense urban area between the San Francisco International Airport (SFO) and central San Francisco. Examples will be provided for pipeline segments installed in various casing types, including sections inserted through utility infrastructure that was made available for use as a gas pipeline casing. Examples include pipe that was installed in the 1940’s and cased pipe installed without corrosion test stations. In some instances, the length of cased pipe sections were several hundred feet long and traversed locations difficult to access, such as major highway crossings and cased spans above water crossings. These inspections were executed in 2015 on 24 separate pipeline segments totaling more than 12,000 feet of pipeline. This paper explains how the inspection team utilized current technology and identified Non-Traditional ILI (NT ILI) as the preferred method. It also explains how the locations were scoped, project parameters and program strategy were developed, NT ILI tool selection, project outcomes, and lessons learned. An overview of the advantages of NT ILI methods to perform these cased pipeline inspections in-lieu of External Corrosion Direct Assessment (ECDA) and Traditional ILI will be discussed. This paper is applicable to Track 3 (Pipelines & Facilities Integrity) and also to Track 2 (Project Management, Design, Construction & Environmental Issues), and will be of interest to Pipeline Operators, Integrity Management Engineers, and Project Managers. The intent is to share PG&E’s experience utilizing Non-Traditional robotic ILI tools to perform difficult pipeline inspections in casings, as well as practical advice on scoping, planning, and execution of non-traditional ILI projects.
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