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1

Meluh, P. B., and D. Koshland. "Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C." Molecular Biology of the Cell 6, no. 7 (1995): 793–807. http://dx.doi.org/10.1091/mbc.6.7.793.

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The MIF2 gene of Saccharomyces cerevisiae has been implicated in mitosis. Here we provide genetic evidence that MIF2 encodes a centromere protein. Specifically, we found that mutations in MIF2 stabilize dicentric minichromosomes and confer high instability (i.e., a synthetic acentric phenotype) to chromosomes that bear a cis-acting mutation in element I of the yeast centromeric DNA (CDEI). Similarly, we observed synthetic phenotypes between mutations in MIF2 and trans-acting mutations in three known yeast centromere protein genes-CEP1/CBF1/CPF1, NDC10/CBF2, and CEP3/CBF3B. In addition, the mif
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2

Baker, Richard E., Kendra Harris, and Keming Zhang. "Mutations Synthetically Lethal with cep1 Target S. cerevisiae Kinetochore Components." Genetics 149, no. 1 (1998): 73–85. http://dx.doi.org/10.1093/genetics/149.1.73.

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Abstract CP1 (encoded by CEP1) is a Saccharomyces cerevisiae chromatin protein that binds a DNA element conserved in centromeres and in the 5′-flanking DNA of methionine biosynthetic (MET) genes. Strains lacking CP1 are defective in chromosome segregation and MET gene transcription, leading to the hypothesis that CP1 plays a general role in assembling higher order chromatin structures at genomic sites where it is bound. A screen for mutations synthetically lethal with a cep1 null allele yielded five recessive csl (cep1 synthetic lethal) mutations, each defining a unique complementation group.
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3

O'Connell, K. F., and R. E. Baker. "Possible cross-regulation of phosphate and sulfate metabolism in Saccharomyces cerevisiae." Genetics 132, no. 1 (1992): 63–73. http://dx.doi.org/10.1093/genetics/132.1.63.

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Abstract CP1 (encoded by the gene CEP1) is a sequence-specific DNA binding protein of Saccharomyces cerevisiae that recognizes a sequence element (CDEI) found in both yeast centromeres and gene promoters. Strains lacking CP1 exhibit defects in growth, chromosome segregation and methionine biosynthesis. A YEp24-based yeast genomic library was screened for plasmids which suppressed the methionine auxotrophy of a cep1 null mutant. The suppressing plasmids contained either CEP1 or DNA derived from the PHO4 locus. Subcloning experiments confirmed that suppression correlated with increased dosage of
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4

Masison, D. C., and R. E. Baker. "Meiosis in Saccharomyces cerevisiae mutants lacking the centromere-binding protein CP1." Genetics 131, no. 1 (1992): 43–53. http://dx.doi.org/10.1093/genetics/131.1.43.

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Abstract CP1 (encoded by the CEP1 gene) is a centromere binding protein of Saccharomyces cerevisiae that binds to the conserved DNA element I (CDEI) of yeast centromeres. To investigate the function of CP1 in yeast meiosis, we analyzed the meiotic segregation of CEN plasmids, nonessential chromosome fragments (CFs) and chromosomes in cep1 null mutants. Plasmids and CFs missegregated in 10-20% of meioses with the most frequent type of aberrant event being precocious sister segregation at the first meiotic division; paired and unpaired CFs behaved similarly. An unpaired chromosome I homolog (2N
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5

Alunno, A., O. Bistoni, F. Pratesi, et al. "Association between anti-citrullinated alpha enolase antibodies and clinical features in a cohort of patients with rheumatoid arthritis: a pilot study." Reumatismo 70, no. 2 (2018): 67. http://dx.doi.org/10.4081/reumatismo.2018.1028.

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In recent years several antibodies against citrullinated peptides (ACPAs) have been identified in patients with rheumatoid arthritis (RA) and their pathogenic, diagnostic and prognostic significance is under intense investigation. Among ACPAs, those targeting citrullinated alpha enolase (anti-CEP1) have been identified in RA but data about their ability to predict the development of erosive disease are conflicting. Furthermore, no data are currently available concerning their possible association with extra-articular manifestations (EAMs) in RA. The aim of this study was to investigate the pre
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6

Baker, R. E., and D. C. Masison. "Isolation of the gene encoding the Saccharomyces cerevisiae centromere-binding protein CP1." Molecular and Cellular Biology 10, no. 6 (1990): 2458–67. http://dx.doi.org/10.1128/mcb.10.6.2458-2467.1990.

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CP1 is a sequence-specific DNA-binding protein of the yeast Saccharomyces cerevisiae which recognizes the highly conserved DNA element I (CDEI) of yeast centromeres. We cloned and sequenced the gene encoding CP1. The gene codes for a protein of molecular weight 39,400. When expressed in Escherichia coli, the CP1 gene directed the synthesis of a CDEI-binding protein having the same gel mobility as purified yeast CP1. We have given the CP1 gene the genetic designation CEP1 (centromere protein 1). CEP1 was mapped and found to reside on chromosome X, 2.0 centimorgans from SUP4. Strains were constr
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7

Baker, R. E., and D. C. Masison. "Isolation of the gene encoding the Saccharomyces cerevisiae centromere-binding protein CP1." Molecular and Cellular Biology 10, no. 6 (1990): 2458–67. http://dx.doi.org/10.1128/mcb.10.6.2458.

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CP1 is a sequence-specific DNA-binding protein of the yeast Saccharomyces cerevisiae which recognizes the highly conserved DNA element I (CDEI) of yeast centromeres. We cloned and sequenced the gene encoding CP1. The gene codes for a protein of molecular weight 39,400. When expressed in Escherichia coli, the CP1 gene directed the synthesis of a CDEI-binding protein having the same gel mobility as purified yeast CP1. We have given the CP1 gene the genetic designation CEP1 (centromere protein 1). CEP1 was mapped and found to reside on chromosome X, 2.0 centimorgans from SUP4. Strains were constr
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8

Luo, Sha, Yao Xiao, Asjad Ali, et al. "Structural Characteristics and Immunological Function of a New Non-Starch Polysaccharide from Red Sprout Taro." Foods 13, no. 22 (2024): 3531. http://dx.doi.org/10.3390/foods13223531.

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Taro is a tuber crop that is used for nutritional and medicinal purposes due to its abundance of non-starch polysaccharides (NSPs). Red Sprout taro is a local variety in Southern China, but the characteristics and bioactivities of its NSPs are currently unknown. In this study, NSPs were isolated from the corms of Red Sprout taro using hot-water extraction, ion-exchange chromatography, and ethanol precipitation; their molecular weight, monosaccharide composition, structural formulae, and immunomodulatory effects were examined. A novel NSP named Colocasia esculenta polysaccharide 1 (CEP1) was pu
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9

Alunno, A., F. Carubbi, O. Bistoni, et al. "FRI0565 PREVALENCE AND SIGNIFICANCE OF ANTIBODIES AGAINST CITRULLINATED ALPHA-ENOLASE (ANTI-CEP1) IN CONNECTIVE TISSUE DISEASES." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 885.2–885. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4549.

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Background:Anti-cyclic citrullinated peptide (anti-CCP) auto-antibodies represent the current gold standard for the diagnosis of rheumatoid arthritis (RA). However, growing evidence suggests that a variety of other citrullinated self-proteins may act as autoantigens and lead to the production of autoantibodies (1). Furthermore, autoantibodies believed to be RA-specific have been detected also in patients with connective tissue diseases (CTDs). We recently demonstrated that antibodies against citrullinated alpha-enolase (anti-CEP1) are a biomarker of erosive disease and RA-associated interstiti
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10

Alunno, A., O. Bistoni, F. Carubbi, et al. "POS0755 PREVALENCE AND RELEVANCE OF ANTIBODIES AGAINST CITRULLINATED ALPHA ENOLASE (ANTI-CEP1) IN CONNECTIVE TISSUE DISEASES." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 630.1–630. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2825.

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Background:Anti-citrullinated alpha enolase antibodies have been investigated in rheumatoid arthritis and associated with bone erosion and interstitial lung disease but little is known about their prevalence and role in connective tissue diseases (CTDs).Objectives:The aim of this study was to investigate the prevalence and relevance of anti-CEP1 antibodies in CTDs.Methods:Serum samples from five independent patient cohorts were assessed: 1) established (est) primary Sjogren’s syndrome (pSS) N=78, 2) est-systemic lupus erythematosus (SLE) N=52, 3) est-systemic sclerosis (SSc) N=71, 4) pSS at di
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11

Guo, Xiaorui, Lihong Li, Xiatong Liu, et al. "MYB2 Is Important for Tapetal PCD and Pollen Development by Directly Activating Protease Expression in Arabidopsis." International Journal of Molecular Sciences 23, no. 7 (2022): 3563. http://dx.doi.org/10.3390/ijms23073563.

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Tapetal programmed cell death (PCD) is a complex biological process that plays an important role in pollen formation and reproduction. Here, we identified the MYB2 transcription factor expressed in the tapetum from stage 5 to stage 11 that was essential for tapetal PCD and pollen development in Arabidopsis thaliana. Downregulation of MYB2 retarded tapetal degeneration, produced defective pollen, and decreased pollen vitality. EMSA and transcriptional activation analysis revealed that MYB2 acted as an upstream activator and directly regulated expression of the proteases CEP1 and βVPE. The expre
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Jenkins, R. B., K. V. Ballman, C. Giannini, et al. "Diagnostic and prognostic significance of a t(1;19)(q10;p10) in patients (pts) with low-grade oligodendroglioma and astrocytoma: NCCTG 94–72–53." Journal of Clinical Oncology 24, no. 18_suppl (2006): 1505. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.1505.

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1505 Background: Combined deletion of chromosomes 1p and 19q is associated with improved prognosis in pts with anaplastic oligodendroglioma. We recently discovered that the combined deletion is mediated by a chromosome 1;19 translocation: t(1;19)(q10;p10). The prognostic significance of this alteration in pts with low-grade gliomas is not known. Methods: Paraffin-embedded tumor tissue was obtained from 134 pts enrolled in two NCCTG trials for newly-diagnosed low-grade glioma: 86–72–51: a randomized phase III trial of 50.4 Gy vs 64.8 Gy radiation therapy (RT) and 93–72–02: a phase II trial of P
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13

Cheng, Ziyi, Xiaorui Guo, Jiaxue Zhang та ін. "βVPE is involved in tapetal degradation and pollen development by activating proprotease maturation in Arabidopsis thaliana". Journal of Experimental Botany 71, № 6 (2019): 1943–55. http://dx.doi.org/10.1093/jxb/erz560.

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Abstract Vacuolar processing enzyme (VPE) is responsible for the maturation and activation of vacuolar proteins in plants. We found that βVPE was involved in tapetal degradation and pollen development by transforming proproteases into mature protease in Arabidopsis thaliana. βVPE was expressed specifically in the tapetum from stages 5 to 8 of anther development. The βVPE protein first appeared as a proenzyme and was transformed into the mature enzyme before stages 7–8. The recombinant βVPE protein self-cleaved and transformed into a 27 kDa mature protein at pH 5.2. The mature βVPE protein coul
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14

O'Connell, K. F., Y. Surdin-Kerjan, and R. E. Baker. "Role of the Saccharomyces cerevisiae general regulatory factor CP1 in methionine biosynthetic gene transcription." Molecular and Cellular Biology 15, no. 4 (1995): 1879–88. http://dx.doi.org/10.1128/mcb.15.4.1879.

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Saccharomyces cerevisiae general regulatory factor CP1 (encoded by the gene CEP1) is required for optimal chromosome segregation and methionine prototrophy. MET16-CYC1-lacZ reporter constructs were used to show that MET16 5'-flanking DNA contains a CP1-dependent upstream activation sequence (UAS). Activity of the UAS required an intact CP1-binding site, and the effects of cis-acting mutations on CP1 binding and UAS activity correlated. In most respects, MET16-CYC1-lacZ reporter gene expression mirrored that of chromosomal MET16; however, the endogenous gene was found to be activated in respons
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15

Yamamoto, Katsuya, Hiroki Kawano, Shinichiro Nishikawa, Kimikazu Yakushijin, Atsuo Okamura, and Toshimitsu Matsui. "A biphenotypic transformation of 8p11 myeloproliferative syndrome with CEP1/FGFR1 fusion gene." European Journal of Haematology 77, no. 4 (2006): 349–54. http://dx.doi.org/10.1111/j.1600-0609.2006.00723.x.

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16

Javerzat, Jean-Paul, Gordon McGurk, Gwen Cranston, et al. "Defects in Components of the Proteasome Enhance Transcriptional Silencing at Fission Yeast Centromeres and Impair Chromosome Segregation." Molecular and Cellular Biology 19, no. 7 (1999): 5155–65. http://dx.doi.org/10.1128/mcb.19.7.5155.

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ABSTRACT Fission yeast centromeres are transcriptionally silent and form a heterochromatin-like structure essential for normal centromere function; this appears analogous to heterochromatin and position effect variegation in other eukaryotes. Conditional mutations in three genes designated cep (centromere enhancer of position effect) were found to enhance transcriptional silencing within centromeres. Cloning of the cep1 + andcep2 + genes by functional complementation revealed that they are identical to the previously described genespad1 + and mts2 +, respectively, which both encode subunits of
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Imin, N., N. A. Mohd-Radzman, H. A. Ogilvie, and M. A. Djordjevic. "The peptide-encoding CEP1 gene modulates lateral root and nodule numbers in Medicago truncatula." Journal of Experimental Botany 64, no. 17 (2013): 5395–409. http://dx.doi.org/10.1093/jxb/ert369.

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18

Jilani, A. A., and C. G. Mackworth-Young. "The Role of Citrullinated Protein Antibodies in Predicting Erosive Disease in Rheumatoid Arthritis: A Systematic Literature Review and Meta-Analysis." International Journal of Rheumatology 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/728610.

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Background. Autoantibodies to citrullinated peptides have been shown to be valuable in the diagnosis of rheumatoid arthritis (RA). The expanding repertoire of antibodies to citrullinated peptide antigens (ACPA) has been a topic of great interest in recent reviews and research studies, as has the ability of these autoantibodies to predict disease outcome.Objectives. The aim of this review was to provide an update on the relevance of ACPA as prognostic markers in RA. The ability to identify patients predisposed to an aggressive outcome at the time of initial diagnosis greatly facilitates the sel
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Feki, S., A. Turki, R. Ben Salah та ін. "Les anticorps anti-peptides α-énolase citrullinés (anti-CEP1) : nouveaux marqueurs diagnostiques pour la polyarthrite rhumatoïde séronégative". La Revue de Médecine Interne 38 (грудень 2017): A170—A171. http://dx.doi.org/10.1016/j.revmed.2017.10.130.

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20

Zhang, Dandan, Di Liu, Xiaomeng Lv, et al. "The Cysteine Protease CEP1, a Key Executor Involved in Tapetal Programmed Cell Death, Regulates Pollen Development in Arabidopsis." Plant Cell 26, no. 7 (2014): 2939–61. http://dx.doi.org/10.1105/tpc.114.127282.

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Singh, Arun D., Raymond Tubbs, Charles Biscotti, Lynn Schoenfield, and Pierre Trizzoi. "Chromosomal 3 and 8 Status Within Hepatic Metastasis of Uveal Melanoma." Archives of Pathology & Laboratory Medicine 133, no. 8 (2009): 1223–27. http://dx.doi.org/10.5858/133.8.1223.

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Abstract Context.—Several studies have evaluated clinical, histopathologic, cytogenetic, and molecular prognostic variables in uveal melanoma. However, it is not known whether the primary tumor cells maintain these aggressive attributes at the metastatic sites. Objective.—To determine the status of chromosomes 3 and 8q and c-myc amplification using fluorescence in situ hybridization on hepatic metastatic lesions of primary uveal melanoma. Design.—Ten patients with uveal melanoma with needle core biopsy–confirmed hepatic metastasis. Representative paraffin blocks were selected based on review o
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Han, Jingyi, Hui Li, Bin Yin, et al. "The papain-like cysteine protease CEP1 is involved in programmed cell death and secondary wall thickening during xylem development in Arabidopsis." Journal of Experimental Botany 70, no. 1 (2018): 205–15. http://dx.doi.org/10.1093/jxb/ery356.

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Cheng, Ziyi, Jiaxue Zhang, Bin Yin та ін. "γVPE plays an important role in programmed cell death for xylem fiber cells by activating protease CEP1 maturation in Arabidopsis thaliana". International Journal of Biological Macromolecules 137 (вересень 2019): 703–11. http://dx.doi.org/10.1016/j.ijbiomac.2019.07.017.

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Zhao, Xiaorong, Ronald Thomason, and Xiao-Xiang Zhang. "Comparison of Immunophenotypic and Genotypic Profiles of Neoplastic Plasma Cells by Use of Flow Cytometric Immunophenotyping and FISH Analysis Following Plasma Cell Enrichment,." Blood 118, no. 21 (2011): 3925. http://dx.doi.org/10.1182/blood.v118.21.3925.3925.

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Abstract Abstract 3925 According to The European Myeloma Network(1), FISH analysis of plasma cell myeloma (multiple myeloma, or MM) should be performed on samples enriched for plasma cells or an assay that allows for identification and study of plasma cells apart from other cells should be utilized. We enriched 400 bone marrow samples sent to our laboratory from May-September 2010 using CD138 antibody microbeads for plasma cells and then performed FISH utilizing probes for CEP3, CEP7, CEP9, CEP11, IgH breakapart, IgH/CCND1 (11;14), IgH/MAF (14;16), IgH/FGFR3(4;14), Rb1/13q, and TP53/CEP17. The
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Xuan, Ying, Qizhong Gao, Chenhu Wang, and Dongyan Cai. "Positive peritoneal lavage fluid cytology based on isolation by size of epithelial tumor cells indicates a high risk of peritoneal metastasis." PeerJ 12 (June 28, 2024): e17602. http://dx.doi.org/10.7717/peerj.17602.

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Background Peritoneal metastasis (PM) is the most prevalent type of metastasis in patients with gastric cancer (GC) and has an extremely poor prognosis. The detection of free cancer cells (FCCs) in the peritoneal cavity has been demonstrated to be one of the worst prognostic factors for GC. However, there is a lack of sensitive detection methods for FCCs in the peritoneal cavity. This study aimed to use a new peritoneal lavage fluid cytology examination to detect FCCs in patients with GC, and to explore its clinical significance on diagnosing of occult peritoneal metastasis (OPM) and prognosis
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Du, Jiang, Li Xu, Yun Cui, Zhaoxia Liu, Yujin Su, and Guilin Li. "Benign notochordal cell tumour: clinicopathology and molecular profiling of 13 cases." Journal of Clinical Pathology 72, no. 1 (2018): 66–74. http://dx.doi.org/10.1136/jclinpath-2018-205441.

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AimsTo study the clinicopathological and molecular features of benign notochordal cell tumours (BNCTs) and their differential diagnosis from chordoma.Methods13 cases of BNCT were investigated. The genome-wide copy number imbalances were performed using Oncoscan CNV array in three cases and fluorescence in situ hybridisation (FISH) detection of epidermal growth factor receptor (EGFR)/chromosome 7 enumeration probe (CEP7), LSI1p36/1q21, LSI19p13/19q13, CEP3/CEP12 and Telvysion 6 P was performed in 13 cases.ResultsAll 13 BNCTs were symptomatic and eight cases showed a close relationship with the
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Roberts, Ianto, Stephanie Smith, Elisabeth Stes, et al. "CEP5 and XIP1/CEPR1 regulate lateral root initiation in Arabidopsis." Journal of Experimental Botany 67, no. 16 (2016): 4889–99. http://dx.doi.org/10.1093/jxb/erw231.

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28

Strunnikov, A. V., J. Kingsbury, and D. Koshland. "CEP3 encodes a centromere protein of Saccharomyces cerevisiae." Journal of Cell Biology 128, no. 5 (1995): 749–60. http://dx.doi.org/10.1083/jcb.128.5.749.

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We have designed a screen to identify mutants specifically affecting kinetochore function in the yeast Saccharomyces cerevisiae. The selection procedure was based on the generation of "synthetic acentric" minichromosomes. "Synthetic acentric" minichromosomes contain a centromere locus, but lack centromere activity due to combination of mutations in centromere DNA and in a chromosomal gene (CEP) encoding a putative centromere protein. Ten conditional lethal cep mutants were isolated, seven were found to be alleles of NDC10 (CEP2) encoding the 110-kD protein of yeast kinetochore. Three mutants d
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Hédé-Haüy, Benoît, and Nicolas Ciaravola. "CEPA et CEPN, au service de l’innovation opérationnelle dans la Marine." Revue Défense Nationale N° 809, no. 4 (2018): 65–71. http://dx.doi.org/10.3917/rdna.809.0065.

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Lopes, Jeane Cândida, Aloisio Freitas Chagas Junior, Gessiel Newton Scheidt, Layssah Passos Soares, and Lillian França Borges Chagas. "Biomassa e extração de quitina e quitosana a partir de isolados de Cunninghamella sp." Semina: Ciências Biológicas e da Saúde 38, no. 1 (2017): 25. http://dx.doi.org/10.5433/1679-0367.2017v38n1p25.

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O estudo objetivou avaliar a produção de biomassa de nove isolados de Cunninghamella sp. e da cepa referência de Cunninghamella elegans (CBMAI 0843) e estabelecer a capacidade de produção de quitina e quitosana por estas cepas. Assim como, caracterizar a quitosana fúngica obtida por parâmetros como massa molar, grau de desacetilação e distribuição dos grupos funcionais ao longo da cadeia polimérica. Para a maioria das cepas avaliadas, o período de maior crescimento foi em 48 horas de cultivo, sendo que, neste período, o isolado UFT Ce08 apresentou a maior quantidade de biomassa, 20,17 g L-1. O
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Matos, Ignacio, Rebeca Lozano, Emilio Fonseca, et al. "Isolation of circulating tumor cells in colon cancer patients by size and chromosomal abnormalities." Journal of Clinical Oncology 31, no. 15_suppl (2013): e22058-e22058. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e22058.

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e22058 Background: Determining the number of circulating tumor cells (CTCs) in patients with metastatic colorectal cancer (CRC) has shown to be a prognostic factor, recent studies have proven the existence of EpCAM and cytokeratin negative CTCs. These cells present morphological and genetic alterations. Our study is based on an algorithm determined by the selection of the size of the cells and the genetic alterations detected by FISH which enables the isolation of CTCs in CRC patients by an automated system of fluorescence. Methods: Patients with metastatic CRC with normal blood differential a
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NIYAZ, MADINIYAT, ABLAJAN ABDURAHMAN, ABDUGHENI TURGHUN, and IDIRIS AWUT. "CEP3 and CEP17 DNA probe potential in the genetic diagnosis and prognostic prediction of esophageal squamous cell cancer." Experimental and Therapeutic Medicine 11, no. 4 (2016): 1375–80. http://dx.doi.org/10.3892/etm.2016.3080.

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Reichenbecher, Marisa, Friedrich Lottspeich, and Karin Bronnenmeier. "Purification and Properties of a Cellobiose Phosphorylase (CepA) and a Cellodextrin Phosphorylase (CepB) from the Cellulolytic Thermophile Clostridium Stercorarium." European Journal of Biochemistry 247, no. 1 (1997): 262–67. http://dx.doi.org/10.1111/j.1432-1033.1997.00262.x.

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Bernasconi, Paolo, Celeste Calvello, Catherine Klersy, et al. "FISH reveals chromosomal abnormalities in 41 Patients with Systemic Amyloidosis (AL)." Blood 116, no. 21 (2010): 1197. http://dx.doi.org/10.1182/blood.v116.21.1197.1197.

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Abstract Abstract 1197 Over the past fifteen years FISH has considerably improved our ability to reveal consistent chromosomal changes in M-GUS, MM and plasma cell leukaemia (PCL), providing evidence of common genetic disease mechanisms and parameters to guide therapeutic decisions. In contrast, this information is still limited in AL due to the rarity of the disease, the low burden and the low proliferative index of clonal PCs. However, recent studies have suggested that in AL FISH, either combined with cytoplasmic staining of specific IgL (cIg-FISH) or performed on immuno-selected PCs, can r
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Lian, Defu, Xing Xie, Vincent W. Zheng, Nicholas Jing Yuan, Fuzheng Zhang, and Enhong Chen. "CEPR." ACM Transactions on Intelligent Systems and Technology 6, no. 1 (2015): 1–27. http://dx.doi.org/10.1145/2629557.

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36

Abdellatif, Ahmed A. H., Amer Mahmood, Mansour Alsharidah, et al. "Bioactivities of the Green Synthesized Silver Nanoparticles Reduced Using Allium cepa L Aqueous Extracts Induced Apoptosis in Colorectal Cancer Cell Lines." Journal of Nanomaterials 2022 (February 4, 2022): 1–13. http://dx.doi.org/10.1155/2022/1746817.

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Allium cepa L (A. cepa) extract is frequently used as an adjuvant food in cancer treatment. We hypothesized that it contains a source of anticancer activity. There is a need to synthesize the silver nanoparticles (AgNPs) using an environment-friendly green synthesis reduction method using an aqueous extract of A. cepa. The AgNPs-CEPA were prepared by reduction method using the aqueous extract of A. cepa. The formed AgNPs-CEPA were characterized for their sizes and charge distribution. The AgNP-CEPA was investigated for its antioxidant and anticancer properties. Cell viability was evaluated by
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Rohani, A. S., S. N. Rudang, R. N. Daulay, T. I. Hanum, and N. A. Juwita. "Characterization, phytochemistry screening and acute toxicity of Allium cepa fermented." IOP Conference Series: Earth and Environmental Science 1241, no. 1 (2023): 012093. http://dx.doi.org/10.1088/1755-1315/1241/1/012093.

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Abstract The health benefit of Allium cepa could be obtained through processing using fermentation technique. This study aimed to obtain standardized fermented onion extract as raw material for medicinal preparations. In addition, this study determined the different content of secondary metabolites of unfermented and fermented Allium cepa then the acute toxicity was conducted to know the LD50.of Allium cepa fermented extract. Fermentation was done by saving the Allium cepa in a fermentation machine for 15 days at a temperature of 50-80°C. Allium cepa fermented was extracted by maceration using
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Irisarri, P. "Un plasmido de Rhizobium loti involucrado en la competencia por la nodulación." Agrociencia 1, no. 1 (1997): 44–49. http://dx.doi.org/10.31285/agro.01.1081.

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La cepa U226 de Rhizobium loti posee un único plásmido críptico de 220 Mdal. Con el objetivo de estudiar funciones codificados por este plásmido, se lo marcó con Tn5-mob-sac y se sometió a la cepa a un tratamiento de cura de plásmido. Se evaluó el comportamiento de la cepa curada y la cepa salvaje en simbiosis con Lotus corniculatus. La eliminación del plásmido no afectó la inefectividad ni la efectividad de la fijación de nitrógeno. Sin embargo, en plántulas de lotus inoculadas con diferentes proporciones de la cepa con el plásmido y la cepa curada, se encontró que la cepa portadora del plásm
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De la Fuente, Juan Ramón. "El CEPE." Decires 5, no. 5 (2001): 15–18. http://dx.doi.org/10.22201/cepe.14059134e.2001.5.5.91.

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Pulido González, Guillermo. "El CEPE." Decires 5, no. 5 (2001): 21–24. http://dx.doi.org/10.22201/cepe.14059134e.2001.5.5.93.

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41

Cann, Howard M. "CEPH maps." Current Opinion in Genetics & Development 2, no. 3 (1992): 393–99. http://dx.doi.org/10.1016/s0959-437x(05)80148-0.

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Cann, Howard M. "CEPH maps." Current Biology 2, no. 6 (1992): 321. http://dx.doi.org/10.1016/0960-9822(92)90889-i.

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Tica, Yvanna Vien. "Cepi Corpus." Prairie Schooner 97, no. 2 (2023): 21–23. http://dx.doi.org/10.1353/psg.2023.a920337.

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Arroyo, Rita, Sonia López, Enrique Romo та ін. "Carboxy-Terminal Cementum Protein 1-Derived Peptide 4 (cemp1-p4) Promotes Mineralization through wnt/β-catenin Signaling in Human Oral Mucosa Stem Cells". International Journal of Molecular Sciences 21, № 4 (2020): 1307. http://dx.doi.org/10.3390/ijms21041307.

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Human cementum protein 1 (CEMP1) is known to induce cementoblast and osteoblast differentiation and alkaline phosphatase (ALP) activity in human periodontal ligament-derived cells in vitro and promotes bone regeneration in vivo. CEMP1′s secondary structure analysis shows that it has a random-coiled structure and is considered an Intrinsic Disordered Protein (IDP). CEMP1′s short peptide sequences mimic the biological capabilities of CEMP1. However, the role and mechanisms of CEMP1′s C-terminal-derived synthetic peptide (CEMP1-p4) in the canonical Wnt/β-catenin signaling pathway are yet to be de
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Mangum, Paul, and Ellen Peffley. "Analysis of (Allium cepa × A. fistulosum) × A. cepa Fourth-generation Backcross Populations for A. fistulosum Introgression." HortScience 35, no. 4 (2000): 568C—568b. http://dx.doi.org/10.21273/hortsci.35.4.568c.

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(Allium cepa × A. fistulosum) × A. cepa breeding lines have been established to the fourth generation. The aim is to develop an A. cepa-like bulbing onion carrying A. fistulosum genes. Seven populations were characterized for morphological traits and three isozyme markers. Each bulb from the populations was characterized for maturity, soluble solids content, bulb shape, and bulb color. All the populations produced A. cepa-like bulbs. Significant variation was observed within each population for each morphological trait. All the bulbs were screened for the presence of A. cepa and A. fistulosum
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Ige, Serah Funke, and Aminat Aderayo Adekola. "Potential of Allium cepa in thromboembolism in Ulcerative Colitis in Rats." Journal of Drug Delivery and Therapeutics 11, no. 3-S (2021): 74–80. http://dx.doi.org/10.22270/jddt.v11i3-s.4879.

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Colitis and coagulation influence each other and patients with colitis have been reported to have an increased risk of thromboembolic events. Allium cepa has been reported to have anti-coagulative activity and anti-inflammatory activity. This research was carried out to investigate the effect of Allium cepa on coagulation changes in colitis
 Twenty eight rats weighed 180 ± 20g were used for this study. They were divided into four groups; Control group, Colitis group, Allium Cepa + Colitis group and Allium Cepa group. Allium Cepa + Colitis group and Allium Cepa were given 1ml/100g body wei
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Santana, Maricela, Gonzalo Montoya, Raúl Herrera, et al. "Cemp1-p3 Peptide Promotes the Transformation of Octacalcium Phosphate into Hydroxyapatite Crystals." Crystals 10, no. 12 (2020): 1131. http://dx.doi.org/10.3390/cryst10121131.

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Dental cementum contains unique molecules that regulate the mineralization process in vitro and in vivo, such as cementum protein 1 (CEMP1). This protein possesses amino acid sequence motifs like the human recombinant CEMP1 with biological activity. This novel cementum protein 1-derived peptide (CEMP1-p3, from the CEMP1’s N-terminal domain: (QPLPKGCAAVKAEVGIPAPH), consists of 20 amino acids. Hydroxyapatite (HA) crystals could be obtained through the combination of the amorphous precursor phase and macromolecules such as proteins and peptides. We used a simple method to synthesize peptide/hydro
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Delay, Christina, Kelly Chapman, Michael Taleski, et al. "CEP3 levels affect starvation-related growth responses of the primary root." Journal of Experimental Botany 70, no. 18 (2019): 4763–74. http://dx.doi.org/10.1093/jxb/erz270.

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AbstractCEPs (C-TERMINALLY ENCODED PEPTIDEs) inhibit Arabidopsis primary root growth by unknown mechanisms. We investigated how CEP3 levels control primary root growth. CEP3 peptide application decreased cell division, S-phase cell number, root meristematic cell number, and meristem zone (MZ) size in a dose- and CEP RECEPTOR1-dependent manner. Grafting showed that CEP3-dependent growth inhibition requires root and shoot CEPR1. CEP3 induced mitotic quiescence in MZ cells significantly faster than that induced by nutrient limitation alone. CEP3 also inhibited the restoration of S-phase to mitoti
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Fuller, Kathy, Henry Hui, Jason Stanley, and Wendy N. Erber. "FISH By Imaging Flow Cytometry in CLL for Diagnosis and MRD Assessment." Blood 138, Supplement 1 (2021): 2619. http://dx.doi.org/10.1182/blood-2021-152266.

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Abstract Chronic lymphocytic leukaemia is a genetically heterogeneous disease with treatment and prognosis varying based on chromosomal abnormalities. These are detectable in up to 80% of cases when tested on the nuclei of interphase cells by fluorescence in situ hybridisation (FISH). Despite the clinical importance of FISH in management, as only up to 200 nuclei are generally assessed, it is not suitable for minimal residual disease (MRD) assessment. Since clinical decisions are based on detection thresholds of 10 -4, MRD assays are restricted to flow cytometry and molecular based assessment.
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Mojarad, Bahareh A., Gagan D. Gupta, Monica Hasegan, et al. "CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme." Open Biology 7, no. 6 (2017): 170114. http://dx.doi.org/10.1098/rsob.170114.

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Primary cilia are microtubule-based sensory organelles necessary for efficient transduction of extracellular cues. To initiate cilia formation, ciliary vesicles (CVs) are transported to the vicinity of the centrosome where they dock to the distal end of the mother centriole and fuse to initiate cilium assembly. However, to this date, the early steps in cilia formation remain incompletely understood. Here, we demonstrate functional interplay between CEP19, FOP and CEP350 in ciliogenesis. Using three-dimensional structured-illumination microscopy (3D-SIM) imaging, we mapped the relative spatial
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