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Relevant bibliographies by topics / Cerebral glucose metabolism / Dissertations / Theses

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Dissertations / Theses on the topic 'Cerebral glucose metabolism'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Warnock, Geoffrey Iain. "Study of the central corticotrophin-releasing factor system using the 2-deoxyglucose method for measurement of local cerebral glucose utilisation." Thesis, University of Bath, 2007. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492291.

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Stress is defined as a challenge to homeostatic equilibrium by physical or psychological events, generating a coping response consisting of central and peripheral changes, with the aim of exerting control over the threatening events. Corticotropin-releasing factor (CRF) is well known as a hypothalamic factor which controls the hypothalamic-pituitary-adrenocortical (HPA) axis during basal activity and stress. CRF also serves a neurotransmitter function in the brain, where it is implicated in a range of stress-related behaviours. The measurement of local cerebral glucose utilisation (LCGU) using

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2

Seaton, Tracy Ann. "Actions of thioctic acid on cerebral glucose utilisation and glutathione metabolism in relation to Parkinson's disease." Thesis, King's College London (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297268.

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3

Vasconcelos, Vívian Sarmento de. "Expressão do transportador de glicose GLUT3 e atividade da acetilcolinesterase em cérebro de ratos adultos submetidos à desnutrição no início da vida." Universidade Federal de Alagoas, 2009. http://repositorio.ufal.br/handle/riufal/632.

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The protein-energy malnutrition is one of the most serious nutritional problems that occur in developing countries. The energy and nutritional deficiency in early life can cause significant changes in different stages of development of central nervous system, since the cases of hyperplasia, hypertrophy and myelinization occur in more intense. The brain uses glucose as its main energy substrate. However, under certain physiological conditions, as during the weaning or during prolonged fasting, the cells may use other substrates in order to meet their metabolic needs. The transport of glucose to

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4

Katsumi, Yukinori. "Cholinergic projection from the basal forebrain and cerebral cortical glucose metabolism in rats. An animal positron emission tomography study." Kyoto University, 2000. http://hdl.handle.net/2433/180833.

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5

Nielsen, Henrietta M., Kewei Chen, Wendy Lee та ін. "Peripheral apoE isoform levels in cognitively normal APOE ε3/ε4 individuals are associated with regional gray matter volume and cerebral glucose metabolism". BIOMED CENTRAL LTD, 2017. http://hdl.handle.net/10150/622812.

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Background: Carriers of the APOE epsilon 4 allele are at increased risk of developing Alzheimer's disease (AD), and have been shown to have reduced cerebral metabolic rate of glucose (CMRgl) in the same brain areas frequently affected in AD. These individuals also exhibit reduced plasma levels of apolipoprotein E (apoE) attributed to a specific decrease in the apoE4 isoform as determined by quantification of individual apoE isoforms in APOE epsilon 4 heterozygotes. Whether low plasma apoE levels are associated with structural and functional brain measurements and cognitive performance remains

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6

Zetterling, Maria. "Clinical Studies in the Acute Phase of Subarachnoid Haemorrhage." Doctoral thesis, Uppsala universitet, Neurokirurgi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-129160.

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Patients admitted in similar clinical condition after spontaneous SAH can develop very different clinical courses. This could depend on the severity of the initial global ischemic brain injury at ictus. In the present study, we explored relations between clinical and radiological parameters at admission that indicate a more severe initial impact, and the following days hormone levels and brain metabolism. Early global cerebral oedema (GCE) on computed tomography occurred in 57 % of SAH patients and was associated with a more severe clinical condition. The brain’s glucose metabolism, measured w

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7

Keli, Barcelos Gleicy. "Valeur pronostique du « monitoring » du métabolisme énergétique cérébral chez les patients victimes d’une hémorragie sous-arachnoïdienne grave." Thesis, Lyon 1, 2012. http://www.theses.fr/2012LYO10300.

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Le ratio métabolique (MR) est un marqueur du métabolisme cérébral. Dans notre travail, nous avons démontré sa valeur pronostique chez 68 patients victimes d’une hémorragie sous-arachnoïdienne anévrysmale grave. En effet, une diminution du MR sous le seuil de 3,35 traduit un phénomène d’hyperglycolyse relative, dont le nombre d’événement est prédictive d’un pronostic défavorable avec une excellente sensibilité et spécificité. L’obtention de ces résultats est rendue possible, notamment après une phase de validation dans un modèle animal de procédures permettant de limiter les effets de facteurs

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8

Figueiras, Francisca Patuleia 1984. "Dual-tracer molecular neuroimaging : methodological improvements and biomedical applications." Doctoral thesis, Universitat Pompeu Fabra, 2012. http://hdl.handle.net/10803/84176.

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Positron emission tomography (PET) is a functional imaging method that allows studying physiological, biochemical or pharmacological processes in vivo. PET is being used in both research and clinical practice. In the brain, it has been used to investigate metabolism, receptor binding, and alterations in regional blood flow. This thesis involves both preclinical and clinical dual-tracer PET imaging studies of different neurological disorders. In this way, different radiotracers were used along the projects. The first project focused on the implementation and in vivo validation of the simultaneo

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9

Tholance, Yannick. "Suivi du métabolisme énergétique cérébral chez les patients victimes d'hémorragies sous-arachnoïdiennes graves : intérêt pour le pronostic individuel et le diagnostic des complications ischémiques." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10232/document.

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L'intérêt du suivi du métabolisme énergétique cérébral dans la prise en charge des patients victimes d'hémorragie sous-arachnoïdienne anévrismale (aSAH) grave reste actuellement controversé en raison de l'absence de valeurs seuils décisionnelles applicables en pratique. Ce travail avait pour objectif de réévaluer l'intérêt des paramètres biochimiques de trois techniques, la microdialyse intracérébrale (cMD), la mesure de la pression tissulaire cérébrale en oxygène (PbtO2) et le cathéter rétrograde jugulaire, pour prédire l’issue fonctionnelle de ces patients et diagnostiquer la survenue d'un i

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10

BOUJABIT, MIBARK. "Anatomie des mecanismes de l'evocation mnesique etude par analyse du metabolisme cerebral du 6-c14-glucose chez le rat." Paris 11, 1997. http://www.theses.fr/1997PA112409.

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Ce travail a pour objectif d'aborder l'etude des mecanismes de l'evocation mnesique mis en jeu lors de la presentation d'indices de rappel, apres un apprentissage partiel d'evitement actif en discrimination lumineuse, realise dans un labyrinthe en y. Pour cela nous avons etudie les modifications de l'activite metabolique du 6-c14-glucose dans 61 structures cerebrales, apres la presentation d'indices de rappel qui facilitent la performance de retention, comme l'exposition au stimulus discriminatif (sd) apres un intervalle de retention de 1 jour et au contexte experimental apres 21 jours. Les re

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11

Annane, Djillali. "Relations entre le phenotype metabolique cerebral et cardiaque et le genotype dans la dystrophie myotonique." Paris 5, 1995. http://www.theses.fr/1995PA05W080.

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12

Kumari, Ratna L. "Studies on rat cerebral glucose metabolism in hyperammonemia." Thesis, 1990. http://hdl.handle.net/2009/838.

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13

Wu, Yi-Zhen, and 吳懿真. "The Relation between Visual Organization Ability and the Metabolism of Cerebral Glucose in Mild Alzheimer disease." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/84362261992239423407.

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碩士<br>高雄醫學大學<br>心理學系碩士班<br>103<br>Background and Goal: Dementia is a clinical syndrome, which affects the patient’s cortical function and causes the degeneration and abnormality of lots of cognitive functions, influencing severely the intelligence that has finished being developed. Alzheimer disease is the most common type of dementia, and also a kind of neurodegenerative disease that is irreversible for now. The commonest earlier symptom is that it will worsen the patient’s memory, making him or her unable to memorize new things. And with the progression of disease, many cognitive functions w

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14

Strome, Elissa Marie. "The effects of intracerebroventricular corticotropin-releasing factor (CRF) on the behaviour and cerebral glucose metabolism of non-human primates." Thesis, 2001. http://hdl.handle.net/2429/11905.

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Corticotropin-releasing factor (CRF) is a peptide neurotransmitter involved in the mammalian stress response, and also plays a key role in the mediation of fear and anxiety-like behaviours in animals. In rats, intracerebroventricular (ICV) CRF induces anxiety-like behaviour, and in rhesus monkeys, CRF administration produces distinct behavioural changes, including lying down, huddling, wallfacing and decreased locomotion. In humans, increased activity within CRF neurons has been associated with psychiatric disorders such as anxiety and major depression. The resemblance of the behavioura

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15

Kinnunen, Leann Helka. "Evidence of a neurochemical difference between the brains of exclusively homosexual and exclusively heterosexual men : differential effects of fluoxetine on cerebral glucose metabolism /." 2001. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pqdiss&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft_dat=xri:pqdiss:3029510.

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16

FREDDI, ILARIA. "Quantificazione del Rate Metabolico Cerebrale del Glucosio nella 18F-FDG-PET." Doctoral thesis, 2011. http://hdl.handle.net/2158/609080.

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17

Femminella, Grazia Daniela. "Influenza della neuroinfiammazione sul volume dell'ippocampo e sul metabolismo cerebrale di glucosio in pazienti con malattia di Alzheimer ed in pazienti con Parkinson-demenza." Tesi di dottorato, 2015. http://www.fedoa.unina.it/10286/1/Femminella_GraziaDaniela_27.pdf.

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La neuroinfiammazione, ovvero la risposta infiammatoria che si manifesta a livello del sistema nervoso centrale (SNC) in seguito ad un insulto, sembra svolgere un ruolo importante nella patogenesi delle malattie neurodegenerative croniche, come la malattia di Alzheimer (MA) e la demenza di Parkinson (PD). In tali patologie, studi post-mortem hanno evidenziato la colocalizzazione delle cellule microgliali, i principali mediatori cellulari della risposta infiammatoria del SNC, sia con le placche di beta-amiloide che con i corpi di Lewy, caratteristiche formazioni patologiche riscontrate nella MA

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