Academic literature on the topic 'Cerebral small vessel disease'

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Journal articles on the topic "Cerebral small vessel disease"

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Litak, Jakub, Marek Mazurek, Bartłomiej Kulesza, et al. "Cerebral Small Vessel Disease." International Journal of Molecular Sciences 21, no. 24 (2020): 9729. http://dx.doi.org/10.3390/ijms21249729.

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Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders with different pathological backgrounds. The advanced vasculature net of cerebral vessels, including small arteries, capillaries, arterioles and venules, is usually affected. Processes of oxidation underlie the pathology of CSVD, promoting the degenerative status of the epithelial layer. There are several classifications of cerebral small vessel diseases; some of them include diseases such as Binswanger’s disease, leukoaraiosis, cerebral microbleeds (CMBs) and lacunar strokes. This paper presents the charac
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Li, Qian, Yang Yang, Cesar Reis, et al. "Cerebral Small Vessel Disease." Cell Transplantation 27, no. 12 (2018): 1711–22. http://dx.doi.org/10.1177/0963689718795148.

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Cerebral small vessel disease (CSVD) is composed of several diseases affecting the small arteries, arterioles, venules, and capillaries of the brain, and refers to several pathological processes and etiologies. Neuroimaging features of CSVD include recent small subcortical infarcts, lacunes, white matter hyperintensities, perivascular spaces, microbleeds, and brain atrophy. The main clinical manifestations of CSVD include stroke, cognitive decline, dementia, psychiatric disorders, abnormal gait, and urinary incontinence. Currently, there are no specific preventive or therapeutic measures to im
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Joutel, Anne, and Frank M. Faraci. "Cerebral Small Vessel Disease." Stroke 45, no. 4 (2014): 1215–21. http://dx.doi.org/10.1161/strokeaha.113.002878.

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Rost, Natalia S., and Mark Etherton. "Cerebral Small Vessel Disease." CONTINUUM: Lifelong Learning in Neurology 26, no. 2 (2020): 332–52. http://dx.doi.org/10.1212/con.0000000000000841.

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Shaaban, C. Elizabeth, and Jeremy Molad. "Cerebral small vessel disease." Neurology 94, no. 21 (2020): 909–10. http://dx.doi.org/10.1212/wnl.0000000000009477.

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Mitchell, Gary F. "Cerebral small vessel disease." Journal of Hypertension 33, no. 10 (2015): 2025–28. http://dx.doi.org/10.1097/hjh.0000000000000717.

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Lam, Ada, M. Anne Hamilton-Bruce, Jim Jannes, and Simon A. Koblar. "Cerebral Small Vessel Disease." Molecular Diagnosis & Therapy 12, no. 3 (2008): 145–56. http://dx.doi.org/10.1007/bf03256279.

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Kitahara, Sho, Shoichiro Ando, Taisuke Kato, et al. "Controlling Cerebral Small Vessel Disease by Elucidating Hereditary Cerebral Small Vessel Disease." Nihon Naika Gakkai Zasshi 112, no. 7 (2023): 1286–91. http://dx.doi.org/10.2169/naika.112.1286.

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Munoz, David G. "Small Vessel Disease: Neuropathology." International Psychogeriatrics 15, S1 (2003): 67–69. http://dx.doi.org/10.1017/s1041610203008986.

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Diseases of small cerebral blood vessels are heterogeneous in etiology and manifestations. Lipohyalinosis, venous collagenosis, amyloid angiopathy, and CADASIL affect different populations of blood vessels. Large and small hemorrhages, lacunae, cortical microinfarcts, and leukoaraiosis are the most important consequences of the small vessel angiopathies. Altered permeability as well as ischemia may be involved in the pathogenesis of the latter.
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Oros, M. M. "Cognitions and chronic cerebrovascular disease (small vessel disease)." INTERNATIONAL NEUROLOGICAL JOURNAL 17, no. 5 (2021): 76–81. http://dx.doi.org/10.22141/2224-0713.17.5.2021.238526.

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Vascular cognitive diseases (VCD) are the conditions when cerebrovascular diseases result in cognitive impairment. However, these diseases can lead by themselves to cognitive deficiency and amount to 15–30 % of dementia cases. It is important that age-associated cognitive impairments commonly resulted from comorbid vascular and neurogenerative pathologies. Among many mechanisms involving in VCD, cerebral small vessel disease is likely to be the most common and results in cognitive impairment regardless of the stroke. VCD is characterized by abnormalities affecting the brain structure and funct
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Dissertations / Theses on the topic "Cerebral small vessel disease"

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Tan, Yan Ying Rhea. "Genetics of cerebral small vessel disease." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/283203.

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Cerebral small vessel disease (SVD) is a leading cause of stroke and vascular dementia. The majority of cases are sporadic, occurring in the elderly hypertensive population. However, there also exist patients with familial disease. The most common form is Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), caused by mutations in the NOTCH3 gene. In recent years, other genes have also been found to cause familial SVD, such as COL4A1/A2, HTRA1, FOXC1 and TREX1. Genome wide association studies (GWAS) have also revealed loci associated with sporadi
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Potter, Gillian Margaret. "Neuroimaging of cerebral small vessel disease." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5598.

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Lacunar stroke accounts for one quarter of all ischaemic stroke and in the long term carries a greater risk of death and disability than was previously realised. Much of our current knowledge originated from neuropathological studies in the 1950s and 1960s. In the last thirty years, brain computed tomography (CT) and magnetic resonance imaging (MRI) have revolutionised our understanding of lacunar stroke and associated features of cerebral small vessel disease (SVD), namely white matter lesions (WML), enlarged perivascular spaces (EPVS) and brain microbleeds (BMB). The purpose of the projects
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Gormley, Kelly. "The genetic basis of cerebral small vessel disease." Thesis, St George's, University of London, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441269.

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Rannikmäe, Kristiina. "Genetic associations with sporadic cerebral small vessel disease." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/23585.

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Background: Cerebral small vessel disease (SVD) causes substantial cognitive, psychiatric and physical disabilities. Despite its common nature, SVD pathogenesis and molecular mechanisms remain poorly understood, and prevention and treatment are probably suboptimal. Identifying the genetic determinants of SVD will improve understanding and may help identify novel treatment targets. The aim of this thesis is to better understand genetic associations with SVD through investigating its pathological, radiological and clinical phenotypes. Methods: To unravel the genetic associations with SVD, I used
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Shi, Yulu. "Cerebral blood flow and intracranial pulsatility in cerebral small vessel disease." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/29625.

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Cerebral small vessel disease (SVD) is associated with increased risks of stroke and dementia, however the mechanisms remain unclear. Low cerebral blood flow (CBF) has long been suggested and accepted, but clinical evidence is conflicting. On the other hand, growing evidence suggests that increased intracranial pulsatility due to vascular stiffening might be an alternative mechanism. Pulse-gated phase-contrast MRI is an imaging technique that allows measuring of CBF contemporaneously with pulsatility in multiple vessels and cerebrospinal fluid (CSF) spaces. The overall aim of this thesis was t
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Wiseman, Stewart John. "The role of systemic inflammation in cerebral small vessel disease." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/22915.

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Cerebral small vessel disease (SVD) is a distinct microvascular disorder that can lead to lacunar stroke, an important stroke subtype that accounts for a quarter of all ischaemic strokes. SVD is associated with imaging biomarkers such as white matter hyperintensities (WMH). The cause of SVD is largely unknown, although inflammation and blood-brain barrier failure via endothelial dysfunction have been implicated. Elevated plasma biomarkers of inflammation are associated with coronary heart disease and large vessel stroke but the role of inflammation in SVD is less well understood. Our hypothesi
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Khan, Usman. "Studies on the pathogenesis of cerebral small vessel disease." Thesis, University of London, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539378.

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Duperron, Marie-Gabrielle. "Genetic determinants and clinical significance of cerebral small vessel disease." Thesis, Bordeaux, 2019. http://www.theses.fr/2019BORD0449.

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La maladie des petites artères cérébrales (MPAC) constitue une étiologie importante d’accident vasculaire cérébral (AVC), de déclin cognitif et de démence. Les marqueurs en imagerie par résonance magnétique (IRM) de MPAC comprennent les hypersignaux de la substance blanche (HSB), les infarctus lacunaires (IL), les microsaignements (MS) et les espaces dilatés périvasculaires (EdPV). Une revue systématique et méta-analyse incluant plus de 16,000 participants a permis de mieux caractériser l’association des HSB, IL et MS avec le risque d’AVC et de démence, ainsi que leurs sous-types, et la mortal
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MELAZZINI, LUCA. "IMAGING BIOMARKERS OF CEREBRAL SMALL VESSEL DISEASE IN ADULTS WITH CONGENITAL HEART DISEASE." Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/805883.

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Aim Imaging biomarkers in medical fields other than oncology tend to be confined to research settings. In neuroimaging, biomarkers of cerebral small vessel disease (SVD) have shown promising results for translation into the clinic but need further validation. In this work, we strove for a more clinically-oriented classification of one of the most representative of SVD biomarkers, i.e. white matter hyperintensities (WMHs), on a large cohort of community-dwelling subjects. We also used this classification to better analyse signs of SVD in a selected population of adults with congenital heart
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Lau, Gary Kui Kai. "Cerebral small vessel disease : mechanistic insights, ethnic differences and prognostic value." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:5d9d38c7-9239-4264-9b42-836d6dcdec12.

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Small vessel disease (SVD) accounts for approximately 25% of all strokes and 45% of all dementias. Although the small vessels cannot be visualised with conventional neuroimaging, the pathological changes in the cerebral white and deep grey matter secondary to SVD has been adopted as markers of SVD. These are best appreciated with magnetic resonance imaging (MRI) and includes recent small subcortical infarcts, white matter hyperintensity (WMH), lacunes, cerebral microbleeds and enlarged perivascular spaces (PVSs). There are however a number of outstanding questions regarding these surrogate neu
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Books on the topic "Cerebral small vessel disease"

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Kwa, Vincent Ing Han. Clinical and magnetic resonance observations in cerebral small-vessel disease. [s.n.], 1999.

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P, Pullicino, Caplan Louis R, and Hommel Marc, eds. Cerebral small artery disease. Raven Press, 1993.

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Gorelick, Philip B., and Leonardo Pantoni. Cerebral Small Vessel Disease. Cambridge University Press, 2014.

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Gorelick, Philip B., and Leonardo Pantoni. Cerebral Small Vessel Disease. Cambridge University Press, 2014.

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Gorelick, Philip B., and Leonardo Pantoni. Cerebral Small Vessel Disease. Cambridge University Press, 2014.

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Cerebral Small Vessel Disease. Cambridge University Press, 2014.

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Lee, Seung-Hoon. Stroke Revisited: Cerebral Small Vessel Disease. Springer, 2021.

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Gunda, Bence. Multimodal MRI of Cerebral Small Vessel Disease. INTECH Open Access Publisher, 2012.

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Charidimou, Andreas, Eric Jouvent, and Susanne J. Van Veluw, eds. Cerebral Small Vessel Diseases: From Vessel Alterations to Cortical Parenchymal Injury. Frontiers Media SA, 2020. http://dx.doi.org/10.3389/978-2-88963-587-0.

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Brown, Christina, and Jamie E. Rubin. Moyamoya Disease. Edited by Kirk Lalwani, Ira Todd Cohen, Ellen Y. Choi, and Vidya T. Raman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190685157.003.0032.

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Moyamoya is a rare cerebrovascular disorder characterized by progressive stenosis of the large cerebral arteries. Cerebral ischemia is the most common manifestation in the pediatric population and may present with symptoms of headache, hypertension, blindness, and developmental delay. The gold standard for diagnosis of Moyamoya is digital subtraction angiography but less invasive imaging modalities such as magnetic resonance imaging/angiogram or perfusion magnetic resonance imaging are typically used. Progressive disease is usually treated with surgical revascularization. Indirect revasculariz
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Book chapters on the topic "Cerebral small vessel disease"

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Lee, Seung-Hoon. "Cerebral Small Vessel Disease." In Stroke Revisited: Pathophysiology of Stroke. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-10-1430-7_6.

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Gogia, Bhanu, Richard B. Libman, and Anand V. Patel. "Cerebral Small Vessel Disease." In Hybrid PET/MR Neuroimaging. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-82367-2_66.

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Nyenhuis, David L. "Hypertension, Cerebral Small Vessel Disease, and Cognitive Function." In Hypertension and Stroke. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29152-9_16.

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Geary, Elizabeth K., and David L. Nyenhuis. "Cerebral Small Vessel Disease, Hypertension, and Cognitive Function." In Hypertension and Stroke. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-010-6_13.

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Quinn, Terence J., Stephen Makin, Fergus Doubal, and Julie Staals. "Cerebral Small Vessel Disease and Vascular Cognitive Impairment." In Textbook of Vascular Medicine. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-16481-2_42.

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Iqbal, Aiza, Nicole Yan Chee Lau, Carlin Chang, et al. "Neuroimaging Biomarkers for Diagnosing Cerebral Small Vessel Disease." In Cutting-Edge Diagnostic Technologies in Cardiovascular Diseases. CRC Press, 2025. https://doi.org/10.1201/9781003481621-5.

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Faraz, Fatima, Jeremy Man Ho Hui, Momina Riaz Siddiqui, Haipeng Liu, and Aiza Iqbal. "Applications of Electroencephalography in Detecting Cerebral Small Vessel Disease." In Cutting-Edge Diagnostic Technologies in Cardiovascular Diseases. CRC Press, 2025. https://doi.org/10.1201/9781003481621-4.

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Yu, Yannan, and David Yen-Ting Chen. "Machine Learning for Cerebrovascular Disorders." In Machine Learning for Brain Disorders. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3195-9_29.

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AbstractCerebrovascular disease refers to a group of conditions that affect blood flow and the blood vessels in the brain. It is one of the leading causes of mortality and disability worldwide, imposing a significant socioeconomic burden to society. Research on cerebrovascular diseases has been rapidly progressing leading to improvement in the diagnosis and management of patients nowadays. Machine learning holds many promises for further improving clinical care of these disorders. In this chapter, we will briefly introduce general information regarding cerebrovascular disorders and summarize s
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Chen, Liang, Tong Tong, Chin Pang Ho, et al. "Identification of Cerebral Small Vessel Disease Using Multiple Instance Learning." In Lecture Notes in Computer Science. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24553-9_64.

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Dorrance, Anne M., Bana Abolibdeh, and Janice M. Diaz-Otero. "Cerebral Small Vessel Disease and Vascular Cognitive Impairment: Preclinical Aspects." In Textbook of Vascular Medicine. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-16481-2_26.

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Conference papers on the topic "Cerebral small vessel disease"

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Offenberg, Ryanne, Ana San Román Gaitero, Josien Pluim, Alberto de Luca, Geert Jan Biessels, and Hugo Kuijf. "Multioutput lesion-symptom mapping with explainable artificial intelligence in cerebral small vessel disease." In Computer-Aided Diagnosis, edited by Susan M. Astley and Axel Wismüller. SPIE, 2025. https://doi.org/10.1117/12.3047168.

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Kong, Liwen, Yuying Wang, Shuai Tao, and Jie Zhao. "Prediction of Cognitive Impairment in Cerebral Small Vessel Disease Using an Ensemble Model Based on Gait Parameters." In 2024 7th International Conference on Computer Information Science and Application Technology (CISAT). IEEE, 2024. http://dx.doi.org/10.1109/cisat62382.2024.10695305.

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Ghafoorian, Mohsen, Nico Karssemeijer, Inge van Uden, et al. "Small white matter lesion detection in cerebral small vessel disease." In SPIE Medical Imaging, edited by Lubomir M. Hadjiiski and Georgia D. Tourassi. SPIE, 2015. http://dx.doi.org/10.1117/12.2081597.

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Riad, Medhat M., Bram Platel, Frank-Erik de Leeuw, and Nico Karssemeijer. "Detection of white matter lesions in cerebral small vessel disease." In SPIE Medical Imaging, edited by Carol L. Novak and Stephen Aylward. SPIE, 2013. http://dx.doi.org/10.1117/12.2007940.

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Yao, Zhiyuan, Zhiheng Xie, and Lei Cao. "Medical image segmentation of systemic lupus erythematosus related cerebral small vessel disease." In International Conference on Image, Signal Processing, and Pattern Recognition (ISPP 2023), edited by Paulo Batista and Ram Bilas Pachori. SPIE, 2023. http://dx.doi.org/10.1117/12.2681060.

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Gilroy, Nicola, Laura Dowsett, Aisling McFall, Lorraine Work, and Alyson Miller. "P11 Elevated ADMA levels and their role in cerebral endothelial dysfunction in cerebral small vessel disease." In Scottish Cardiovascular Forum – 28th annual meeting. BMJ Publishing Group Ltd and British Cardiovascular Society, 2025. https://doi.org/10.1136/heartjnl-2025-scf.20.

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Jamil, Afshan, Evangeline Wong, Lushimi Udayakumaran, James Haffernan, Varnika Sharma, and Tina Ahluwalia. "3065 Asymptomatic cerebral small vessel disease (CSVD): an independent risk factor for stroke." In ANZAN Annual Scientific Meeting 2024 Abstracts. BMJ Publishing Group Ltd, 2024. http://dx.doi.org/10.1136/bmjno-2024-anzan.71.

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Robin, Brown, Walsh Jessica, Tozer Daniel, and Markus Hugh. "Do microglial activity and blood brain barrier permeability predict cerebral small vessel disease progression." In Association of British Neurologists: Annual Meeting Abstracts 2023. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jnnp-2023-abn.118.

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Mallick, Akashleena, Alvin Das, Sophia Keins, et al. "Cerebral Small Vessel Disease Subtypes and Blood Pressure Control after Intracerebral Hemorrhage (P7-5.024)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000203594.

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PARK, JIN HO, and KYUNGHA MIN. "The Association between Pulmonary Function and Cerebral Small Vessel Diseases (S49.003)." In 2023 Annual Meeting Abstracts. Lippincott Williams & Wilkins, 2023. http://dx.doi.org/10.1212/wnl.0000000000202196.

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Reports on the topic "Cerebral small vessel disease"

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Zhang, Xinyang, Xuemei Liu, Ruyu Xia, Nannan Li, Xing Liao, and Zhigang Chen. Chinese herbal medicine for vascular cognitive impairment in cerebral small vessel disease: a protocol for systematic review and meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.8.0120.

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Liu, Liushu, and Zhiyou Cai. Association between cerebral small diseases and the risk of Parkinson disease: a systematic review and meta analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.8.0083.

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