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Journal articles on the topic 'Cerebral venous thrombosis (CVT)'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Moraes Junior, Anisio Adalio de Azevedo, and Adriana Bastos Conforto. "Cerebral venous thrombosis." Arquivos de Neuro-Psiquiatria 80, no. 5 suppl 1 (2022): 53–59. http://dx.doi.org/10.1590/0004-282x-anp-2022-s108.

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ABSTRACT Cerebral venous sinus thrombosis (CVT) consists of partial or complete occlusion of a sinus or a cerebral vein. CVT represents 0.5-1% of all strokes and is more frequent in young women. This review discusses particular aspects of CVT diagnosis and management: decompressive craniectomy (DC), anticoagulation with direct oral anticoagulants (DOACs), CVT after coronavirus-disease 19 (COVID-19) and Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT).

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Aamodt, Anne Hege, and Thor Håkon Skattør. "Cerebral Venous Thrombosis." Seminars in Thrombosis and Hemostasis 48, no. 03 (2022): 309–17. http://dx.doi.org/10.1055/s-0042-1742738.

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AbstractCerebral venous thrombosis (CVT) is a rare form of stroke that often affects younger age groups, especially reproductive age group females. CVT is a potentially fatal neurological condition that can be frequently overlooked due to the vague nature of its clinical and radiological presentation. Headache is the most common presenting symptom. However, a wide range of symptoms can be present and the symptom onset can be acute, subacute, or chronic. Neuroimaging is mandatory in cases where CVT is suspected. Both magnetic resonance venography and computed tomography venography can confirm a

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3

Bogdanov, E. I., and A. T. Zabbarova. "Cerebral venous thrombosis." Neurology Bulletin XXXV, no. 1-2 (2003): 52–57. http://dx.doi.org/10.17816/nb89672.

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Classical descriptions of cerebral venous thrombosis (CVT) have been known since the early 19th century and are based on autopsy data. Focal neurological symptoms, seizures, and coma were considered typical clinical manifestations of CVT. Progress in the development of neuroimaging technology has contributed to the expansion of ideas about the etiology, pathogenesis, spectrum of clinical manifestations and the course of this disease. Currently, the most urgent are the problems of early diagnosis and effective therapy of CVT.

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Ruuskanen, Jori O., Ville Kytö, Jussi P. Posti, Päivi Rautava, and Jussi O. T. Sipilä. "Cerebral Venous Thrombosis." Stroke 52, no. 1 (2021): 335–38. http://dx.doi.org/10.1161/strokeaha.120.031026.

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Background and Purpose: Epidemiology of cerebral venous thrombosis (CVT) has been reported to be changing. Because long-term nationwide data are needed to confirm this, we studied CVT occurrence between 2005 and 2014 in Finland. Methods: All acute CVT admissions were retrieved from a mandatory registry covering mainland Finland. Patients aged ≥18 years were included. One admission per patient was allowed. Results: We identified 563 patients with CVT (56.5% women). Overall incidence was 1.32/100 000 (95% CI, 1.21–1.43) per year with a 5.0% annual increase. In people <55 years of age, inciden

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Johansen, Michelle C., Rebecca F. Gottesman, and Victor C. Urrutia. "Cerebral venous thrombosis." Neurology: Clinical Practice 10, no. 2 (2019): 115–21. http://dx.doi.org/10.1212/cpj.0000000000000670.

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BackgroundPlasma cardiac troponin (cTn) elevation occurs in acute ischemic stroke and intracranial hemorrhage and can suggest a poor prognosis. Because acute cerebral venous thrombosis (CVT) might lead to venous stasis, which could result in cardiac stress, it is important to evaluate whether cTn elevation occurs in patients with CVT.MethodsInpatients at Johns Hopkins Hospital from 2005 to 2015 meeting the following criteria were included: CVT (ICD-9 codes with radiologic confirmation) and available admission electrocardiogram (ECG) and cTn level. In regression models, presence of ECG abnormal

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6

Waghmare, Akash, Anurag Luharia, and Suhas Tiwaskar. "Cerebral Venous Thrombosis (CVT)." ECS Transactions 107, no. 1 (2022): 17855–62. http://dx.doi.org/10.1149/10701.17855ecst.

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Altered mental status, which affects four to ten percent of emergency hospital patients, is a common symptom. Without a lot of information from the lab, radiography, and physical exam, determining the aetiology could be challenging. The provider's clinical judgement is used to guide the diagnosis procedure based on the available history. As a result, if a reasonable suspicion is not present when examining alternative reasons, less common diagnosis may be overlooked or delayed. CVST (cerebral venous sinus thrombosis) is an uncommon and poorly understood condition with a high rate of morbidity a

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Oliveira, Isabela Magalhães, Juliana Ávila Duarte, Mariana Dalaqua, Vinicius Menezes Jarry, Fernanda Veloso Pereira, and Fabiano Reis. "Cerebral venous thrombosis: imaging patterns." Radiologia Brasileira 55, no. 1 (2022): 54–61. http://dx.doi.org/10.1590/0100-3984.2021.0019.

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Abstract Cerebral venous thrombosis (CVT) is an uncommon condition that is potentially reversible if properly diagnosed and promptly treated. Although CVT can occur at any age, it most commonly affects neonates and young adults. Clinical diagnosis is difficult because the clinical manifestations of CVT are nonspecific, including headache, seizures, decreased level of consciousness, and focal neurologic deficits. Therefore, imaging is crucial for the diagnosis. Radiologists should be able to identify the findings of CVT and to recognize potential imaging pitfalls that may lead to misdiagnosis.

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Rammos, Stylianos K., Jayme Phillips, Julian Lin, Kenneth Moresco, and Sean Meagher. "Successful rheolytic mechanical thrombectomy of cerebral venous thrombosis in a pediatric patient." Journal of Neurosurgery: Pediatrics 11, no. 2 (2013): 140–43. http://dx.doi.org/10.3171/2012.11.peds12176.

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Thrombosis of the deep cerebral venous system is associated with a significant risk of morbidity and mortality in the pediatric population. Anticoagulation is the mainstay of current treatment of cerebral venous thrombosis (CVT). Systemic or local delivery of thrombolytics may be used in cases of inexorable progression of CVT and neurological compromise. Mechanical thrombectomy has been described in adult patients with CVT and may offer the added advantage of accelerated thrombolysis in the face of rapid clinical deterioration. In this report the authors describe the use of rheolytic mechanica

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9

Aguiar de Sousa, Diana. "Cerebral Venous Thrombosis: What's New?" Hämostaseologie 41, no. 01 (2021): 025–30. http://dx.doi.org/10.1055/a-1332-3042.

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AbstractThrombosis of the cerebral veins and sinuses (CVT) is a distinct cerebrovascular disorder that, unlike arterial stroke, most often affects children and young adults, especially women. In this review, we will summarize recent advances on the knowledge of patients with CVT.

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Koennecke, Hans-Christian. "Cerebral venous thrombosis in adults." Vasa 48, no. 6 (2019): 473–82. http://dx.doi.org/10.1024/0301-1526/a000788.

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Summary. Thromboses of cerebral veins and/or sinuses (CVT) encompass a clinically rather heterogenous, relatively rare entity, which is nonetheless an important cause of stroke in the young. While until the mid of the last century the prognosis of CVT was thought to be poor or even fatal in the majority of cases, the advance and wider use of modern imaging technology since the early 1980s, together with the results of registries and population-based studies, revealed that CVT is more frequent and less life-threatening than previously assumed. However, because headache is frequently the only sy

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Colaco, Vimala, Harsha Sundaramurthy, Shasthara Paneyala, and Nemichandra S. C. "Cerebral venous thrombosis: a changing landscape." International Journal of Research in Medical Sciences 9, no. 9 (2021): 2854. http://dx.doi.org/10.18203/2320-6012.ijrms20213204.

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Cerebral venous thrombosis (CVT) is an uncommon cause of stroke and is mainly a disease of the young. The aims of the study were to summarize the change in the clinical profile of CVT and provide an update regarding the current management of the same. A literature search was conducted using Pubmed and Google scholar using the desired terms. Studies were analysed and review was formulated. The median age of CVT in most studies was 32 years. There has been a shift from female pre-ponderence to equal gender predilection. Several studies are confirming the efficacy of D-dimer as a diagnostic marke

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Alvis-Miranda, Hernando Hernando, Sandra Milena Castellar-Leones, Gabriel Alcala-Cerra, and Luis Rafael Moscote-Salazar. "Cerebral sinus venous thrombosis." Journal of Neurosciences in Rural Practice 04, no. 04 (2013): 427–38. http://dx.doi.org/10.4103/0976-3147.120236.

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ABSTRACTCerebral sinus venous thrombosis (CSVT) is a rare phenomenon that can be seen with some frequency in young patients. CSVT is a multifactorial condition with gender-related specific causes, with a wide clinical presentation, the leading causes differ between developed and developing countries, converting CSVT in a condition characterized by a highly variable clinical spectra, difficult diagnosis, variable etiologies and prognosis that requires fine medical skills and a high suspicious index. Patients who presents with CSVT should underwent to CT-scan venography (CVT) and to the proper i

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Rerikh, K. V., L. A. Shchepankevich, E. V. Taneeva, I. A. Gribacheva, T. F. Popova, and I. N. Novikova. "CEREBRAL VENOUS THROMBOSIS IN WOMEN OF REPRODUCTIVE AGE: CAUSES AND FEATURES OF THE COURSE." Sibirskij medicinskij vestnik 7, no. 1 (2023): 36–40. http://dx.doi.org/10.31549/2541-8289-2023-7-1-36-40.

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Cerebral venous thrombosis (CVT) is a brain lesion due to impaired blood circulation, caused by thrombosis of the intracranial veins and sinuses, leading to an increase in hydrostatic pressure in the proximal veins and capillaries, as a result of which cerebral edema and ischemia develop, and, consequently, cerebral infarction is formed. CVT is especially common in women aged 20 to 35 years, which is largely due to the course of pregnancy and the postpartum period, as well as the use of oral contraceptives. Disturbances in the hemostasis system play a key role in the pathogenesis of these thro

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14

Ulivi, Leonardo, Martina Squitieri, Hannah Cohen, Peter Cowley, and David J. Werring. "Cerebral venous thrombosis: a practical guide." Practical Neurology 20, no. 5 (2020): 356–67. http://dx.doi.org/10.1136/practneurol-2019-002415.

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All neurologists need to be able to recognise and treat cerebral venous thrombosis (CVT). It is difficult to diagnose, partly due to its relative rarity, its multiple and various clinical manifestations (different from ‘conventional’ stroke, and often mimicking other acute neurological conditions), and because it is often challenging to obtain and interpret optimal and timely brain imaging. Although CVT can result in death or permanent disability, it generally has a favourable prognosis if diagnosed and treated early. Neurologists involved in stroke care therefore also need to be aware of the

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Sitnikova, Anastasiya Ivanovna, Lyudmila Anatol'evna Belova, Viktor Vladimirovich Mashin, Lyubov' Vladimirovna Matveeva, and Dmitriy Vyacheslavovich Belov. "VARIANTS OF VENOUS SINUS STRUCTURE IN PATIENTS WITH CEREBRAL VENOUS THROMBOSIS." Ulyanovsk Medico-biological Journal, no. 4 (December 26, 2022): 19–29. http://dx.doi.org/10.34014/2227-1848-2022-4-19-29.

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The aim of the paper is to study venous sinus structure in patients with cerebral venous thrombosis (CVT) depending on constitutional venous insufficiency (CVI). Materials and methods. The study included 50 CVT patients aged 25–77 years (mean age 52.5±14): 15 men (25.6 %) aged 46–75 years (mean age 54±12) and 35 women (74.4 %) aged 25–77 years (mean age 53.5±14). The authors assessed patients’ complaints, anamnesis, neurological status and assigned CVI clinical criteria. All patients underwent magnetic resonance venography. Results. In the study, transverse sinus CVT (24 case

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16

S de Camargo, Erica C., Ayrton R. Massaro, Luiz A. Bacheschi, et al. "Headache in Cerebral Venous Thrombosis." Stroke 32, suppl_1 (2001): 345–46. http://dx.doi.org/10.1161/str.32.suppl_1.345-d.

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P37 Objectives: Although headache is the most frequent and often the earliest symptom of cerebral venous thrombosis (CVT), few studies have attempted to define its clinical features. Our aim is to describe the main characteristics of headache in CVT patients. Methods: From March 1996 to June 2000 we prospectively evaluated 39 patients. After clinical examination, diagnostic confirmation was obtained by magnetic resonance imaging and/or angiography. Information about headache was recorded on a standardized form, including location, severity, duration, quality, worsening and associated features.

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Mazou, N. Temgoua, Essouma Mickael, N. Tangie Larry, Tsinda Cedric, Feze Foko Drusille, and Danwang Celestin. "Cerebral venous thrombosis secondary to an occult maxillary sinusitis in a young male from sub-Saharan Africa." Open Journal of Otolaryngology and Rhinology 1, no. 1 (2019): 08–12. https://doi.org/10.36811/ojor.2019.110002.

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Cerebral venous thrombosis (CVT) also termed cerebral venous sinus thrombosis (CVST), is a special type of cerebrovascular disease characterized by cerebral venous infarction [1]. As from 1825 when the first case was described by Ribes[2], epidemiological descriptions are still restricted to case reports and small retrospective cross-sectional studies yielding low butincreasing incidence: <10 cases per million per year in 1995 to about 13.2 cases per million per year in 2012.CVT mainly occurs in women of child bearing age, probably owing to the use of oral contraceptive pills, and mostly ha

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18

Martinelli, Ida, Valerio De Stefano, Alessandra Carobbio, et al. "Cerebral Vein Thrombosis In Patients With Myeloproliferative Neoplasms." Blood 122, no. 21 (2013): 4068. http://dx.doi.org/10.1182/blood.v122.21.4068.4068.

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Abstract Background Patients with Philadelphia-negative myeloproliferative neoplasms (MPN) can develop venous thrombosis and MPN are the leading cause of splanchnic vein thrombosis. Cerebral vein thrombosis (CVT) is a rare life-threatening disease that in approximately 3% of cases encounters MPN among risk factors and tends to recur in 2-4% of patients as CVT and in 4-7% as venous thrombosis at other sites. Little or no information is available on patients with MPN who develop CVT. Objective and design To investigate the characteristics and clinical course of CVT in patients with MPN we carrie

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Olimova, F. Z., Ye G. Klocheva, V. N. Semich, V. V. Goldobin, S. V. Lobzin, and M. S. Partavi. "Diagnostics of cerebral venous thrombosis associated with COVID-19 in young adults: clinical characteristics and imaging patterns." Diagnostic radiology and radiotherapy 12, no. 3 (2021): 43–53. http://dx.doi.org/10.22328/2079-5343-2021-12-3-43-53.

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Introduction. Cerebral venous thrombosis (CVT) is relatively rare, but leads to the development of cerebral venous infarction, intracranial hemorrhage, followed by severe disability and death. Due to the epidemiological situation caused by COVID-19, the incidence of CVT is increasing.Aims and objectives: to analyze clinical, laboratory instrumental and neuroimaging (multislice computed tomography (MSCT), MSCT — with intravenous contrast, magnetic resonance imaging of the brain (MRI) and MRI venography) data that confirmed the development of CVT in patients with COVID-19.Methods. Data of 5 youn

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Paccagnella, Margherita, Anna Pizzo, Veronica Calabrò, Valerio Velardi, Bruno Fabris, and Stella Bernardi. "Association Between Thyrotoxicosis and Cerebral Venous Thrombosis." Journal of Clinical Medicine 13, no. 21 (2024): 6547. http://dx.doi.org/10.3390/jcm13216547.

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Thyrotoxicosis appears to be a predisposing factor for cerebral venous thrombosis (CVT), which is a rare but important cause of stroke in young adults. The presentation of CVT is highly variable, ranging from a history of headaches (in the majority of cases) to deep coma, with the latter requiring invasive neurosurgical decompression. Although the long-term outcomes of CVT are favorable, multicenter cohort studies have shown that death may occur in up to 4% of cases in the acute phase and 8–10% of cases in the long term. It has been argued that the substantial decrease in mortality in patients

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Krivopalov, Aleksandr A., Aleksandr Yu Shcherbuk, Yurii A. Shcherbuk, Irina I. Sarkisyan, Polina A. Shamkina, and Alexandra I. Glyshchenko. "Cerebral venous thrombosis in otorhinolaryngology. Case report." Consilium Medicum 24, no. 9 (2022): 632–36. http://dx.doi.org/10.26442/20751753.2022.9.201910.

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A violation of cerebral circulation, in which a blood clot forms in the venous system of the brain with the formation of an obstruction of the dural sinus, one or more veins of the brain is called cerebral venous thrombosis. Cerebral venous sinus thrombosis (CVT) is a rare venous thromboembolic event, which accounts for 5 cases per 1 million among adults and about 7 cases per 1 million among children, according to the International Study on Cerebral Vein and Dural Sinus Thrombosis. Women of childbearing age are more susceptible to the disease, which is probably due to hormonal changes during p

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ElSankari, Souraya, Marek Czosnyka, Pierre Lehmann, Marc-Etienne Meyer, Hervé Deramond, and Olivier Balédent. "Cerebral Blood and CSF Flow Patterns in Patients Diagnosed for Cerebral Venous Thrombosis - An Observational Study." Journal of Clinical Imaging Science 2 (July 28, 2012): 41. http://dx.doi.org/10.4103/2156-7514.99158.

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Background and Purpose: Recent studies of the organization of the cerebral venous system in healthy subjects using phase contrast magnetic resonance imaging (PC-MRI) show its structural complexity and inter-individual variations. Our objective was to study the venous blood and CSF flows in cerebral venous thrombosis (CVT). Materials and Methods: PC-MRI sequences were added to brain MRI conventional protocol in 19 patients suspected of CVT, among whom 6 patients had CVT diagnosis confirmed by MR venography. Results were compared with 18 healthy age-matched volunteers (HV). Results: In patients

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Deliran, Shahrzad S., Matthijs C. Brouwer, Jonathan M. Coutinho, and Diederik van de Beek. "Bacterial meningitis complicated by cerebral venous thrombosis." European Stroke Journal 5, no. 4 (2020): 394–401. http://dx.doi.org/10.1177/2396987320971112.

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Introduction Community-acquired bacterial meningitis may be complicated by cerebral venous thrombosis (CVT), but this has not systematically been studied. Methods We evaluated clinical characteristics and outcome of CVT in adults with community-acquired bacterial meningitis in a prospective nationwide cohort study of bacterial meningitis (2006–2018) in the Netherlands. Results CVT occurred in 26 of 2220 episodes with bacterial meningitis (1%). The diagnosis of CVT was made on the day of presentation in 15 patients (58%) and during hospital stay in 11 patients after a median of 6 days (IQR 2–7)

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Miranda, Bruno, Sanjith Aaron, Antonio Arauz, et al. "The benefit of EXtending oral antiCOAgulation treatment (EXCOA) after acute cerebral vein thrombosis (CVT): EXCOA-CVT cluster randomized trial protocol." International Journal of Stroke 13, no. 7 (2018): 771–74. http://dx.doi.org/10.1177/1747493018778137.

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Rationale After a cerebral vein thrombosis, there is an increased risk of further venous thromboembolic events. The optimal duration of anticoagulation after cerebral vein thrombosis is unknown. Aim To compare efficacy and safety of a policy of short- (3–6 months) versus long-term (12 months) anticoagulation (any type venous thromboembolic events) after cerebral vein thrombosis for the prevention of venous thromboembolic events. Sample size estimates A sample of 1428 patients (749 per arm) allows detecting a reduction from 10 to 5% in the risk of venous thromboembolic event recurrence with 80%

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Lavadi, Raj Swaroop, B. V. Sandeep, Manpreet Singh Banga, Sangamesh Halhalli, and Anantha Kishan. "Cerebral venous thrombosis with a catch." Surgical Neurology International 12 (November 30, 2021): 590. http://dx.doi.org/10.25259/sni_1021_2021.

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Background: Cerebral venous thrombosis (CVT) is a rare entity typically occurring in patients in hypercoagulable states. They can also occur in cases of trauma. The symptoms are nonspecific. Case Description: A 28-year-old male presented to the emergency department with a head injury. During the necessary imaging, it was found that he had a depressed skull fracture and other signs of traumatic brain injury. Unbeknownst to the patient and the patient party, it was also revealed that the patient only had one kidney. Wound debridement and excision of the depressed fracture were performed. A posto

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Yadollahikhales, Golnaz, Afshin Borhani-Haghighi, Anahid Safari, Mohammad Wasay, and Randall C.Edgell. "Cerebral venous sinus thrombosis." Galen Medical Journal 5 (May 24, 2016): 48–61. http://dx.doi.org/10.31661/gmj.v5is1.594.

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Cerebral venous thrombosis (CVT) is occlusion of dural sinuses and/or cortical veins due to clot formation. It is a potentially life-threatening condition that requires rapid diagnosis and urgent treatment.Cerebral venous thrombosis is more common in females and young people. Pregnancy, postpartum state, contraceptive pills, infection, malignancy, hyper-coagulable state, rheumatological disorders, trauma are among the major etiologies of cerebral venous thrombosis. Headache, focal neurologic deficits and seizure were the most common clinical presentations. Different techniques of unenhanced an

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Sánchez van Kammen, Mayte, Erik Lindgren, Suzanne M. Silvis, et al. "Late seizures in cerebral venous thrombosis." Neurology 95, no. 12 (2020): e1716-e1723. http://dx.doi.org/10.1212/wnl.0000000000010576.

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ObjectiveTo examine the incidence, characteristics, treatment, and predictors of late seizures (LS) after cerebral venous thrombosis (CVT), we described these features in a registry of 1,127 patients with CVT.MethodsWe included consecutive adult patients from an international consortium of 12 hospital-based CVT registries. We excluded patients with a history of epilepsy or with <8 days of follow-up. We defined LS as seizures occurring >7 days after diagnosis of CVT. We used multivariable Cox regression to identify predictors of LS.ResultsWe included 1,127 patients with CVT. During a medi

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Felício, André Carvalho, Márcia Maiumi Fukujima, Jose Antônio Fiorot Jr, et al. "Cerebral venous thrombosis and hepatitis: case report." Arquivos de Neuro-Psiquiatria 64, no. 4 (2006): 1041–42. http://dx.doi.org/10.1590/s0004-282x2006000600033.

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Among the many infective causes of cerebral venous thrombosis (CVT), viral hepatitis is been regarded as a rare associated condition. We report on a 56-years-old man presenting CVT associated with hepatitis B and C coinfections outlining probable pathogenic mechanisms. We suggest that virus B and C serology should be performed in the cases of cerebral venous thrombosis with unknown etiology.

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Squizzato, Alessandro, Monica Gianni, Maria De Lodovici, et al. "Safety of thrombolysis in cerebral venous thrombosis." Thrombosis and Haemostasis 104, no. 11 (2010): 1055–62. http://dx.doi.org/10.1160/th10-05-0311.

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SummarySeveral small series have suggested the efficacy of thrombolysis in patients with cerebral vein thrombosis (CVT). However, since no randomised controlled trials have compared the use of thrombolysis with anticoagulant treatment in these patients, the risk to benefit ratio of this approach remains uncertain. The aim of this study is therefore to assess the safety of thrombolysis in CVT estimating mortality and major bleeding complications. MEDLINE and EMBASE databases were searched up to June 2010. Two reviewers performed study selection independently. Studies providing data on mortality

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Uyttenboogaart, Maarten, Patrick C. A. J. Vroomen, Jacques De Keyser, Gert-Jan Luijckx, Karen Koopman, and Jan van der Meer. "Risk factors for cerebral venous thrombosis and deep venous thrombosis in patients aged between 15 and 50 years." Thrombosis and Haemostasis 102, no. 10 (2009): 620–22. http://dx.doi.org/10.1160/th09-06-0346.

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SummaryCerebral venous thrombosis (CVT) and deep vein thrombosis or pulmonary embolism (DVT/PE) are associated with many risk factors. It is unclear why CVT occurs less often than DVT/PE. Age dependent risk factors may play a role. The aim of our study was to compare risk factors in a uniform age group of CVT and DVT/PE patients aged between 15 and 50 years. Thrombophilic markers and clinical risk factors of 79 CVT patients and 173 DVT/PE patients aged 15–50 years were compared. Multivariable logistic regression analysis was performed to investigate if risk factors were independently associate

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Jianu, Dragos Catalin, Silviana Nina Jianu, Traian Flavius Dan, et al. "An Integrated Approach on the Diagnosis of Cerebral Veins and Dural Sinuses Thrombosis." Life 12, no. 5 (2022): 717. http://dx.doi.org/10.3390/life12050717.

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(1) Objective: This review paper aims to discuss multiple aspects of cerebral venous thrombosis (CVT), including epidemiology, etiology, pathophysiology, and clinical presentation. Different neuroimaging methods for diagnosis of CVT, such as computer tomography CT/CT Venography (CTV), and Magnetic Resonance Imaging (MRI)/MR Venography (MRV) will be presented. (2) Methods: A literature analysis using PubMed and the MEDLINE sub-engine was done using the terms: cerebral venous thrombosis, thrombophilia, and imaging. Different studies concerning risk factors, clinical picture, and imaging signs of

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Khan, Maria, Ayeesha Kamran Kamal, and Mohammad Wasay. "Controversies of Treatment Modalities for Cerebral Venous Thrombosis." Stroke Research and Treatment 2010 (2010): 1–7. http://dx.doi.org/10.4061/2010/956302.

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Cerebral vein thrombosis has been well recognized for nearly two centuries. However, therapeutic options for the condition are limited due to lack of large randomized trials. The various modalities reportedly used include antiplatelets, anticoagulation, fibrinolysis, and mechanical thrombectomy. Of these, antiplatelets are the least studied, and there are only anecdotal reports of aspirin use. Anticoagulation is the most widely used and accepted modality with favorable outcomes documented in two randomized controlled trials. Various fibrinolytic agents have also been tried. Local infusions hav

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Ehler, Edvard, Aleš Kopal, Milan Mrklovský, and Milan Košťál. "Cerebral Venous Thrombosis after a Cesarean Delivery." Acta Medica (Hradec Kralove, Czech Republic) 53, no. 2 (2010): 109–13. http://dx.doi.org/10.14712/18059694.2016.68.

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Cerebral venous thrombosis (CVT) is a serious condition affecting mostly women. This report concerns two cases of women who developed CVT within 14 days of cesarean delivery. Magnetic resonance angiography of the brain (venous phase) is the best modality to diagnose the condition, and parenteral application of low-molecular-weight heparin is the most beneficial treatment. The first patient was found to have an elevated factor VIII level. In the second patient, homozygosity of the C677T mutation in the 5,10-methylenetetrahydrofolate reductase gene was found. The puerperal period and Cesarean Se

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Fiorot Júnior, José Antonio, André Carvalho Felício, Márcia Mauimi Fukujima, et al. "Tuberculosis: an uncommon cause of cerebral venous thrombosis?" Arquivos de Neuro-Psiquiatria 63, no. 3b (2005): 852–54. http://dx.doi.org/10.1590/s0004-282x2005000500025.

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Several infectious etiologies are related to cerebral venous thrombosis (CVT), but a review of literature showed only few cases related to tuberculosis (TB), and only one with neurological manifestations.We report an unusual case of CVT related to TB and mutation in prothrombin gene. A 38-man black presented abrupt right hemiparestesis, and hemiparesis. Investigations revealed CVT. Cerebral spinal fluid (CSF) examination evidenced a infection by Mycobacterium. He was heterozygous for G20210A prothrombin mutation. Probably, hypercoagulability mechanisms of TB, added to mutation of prothrombim g

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Seerha, Hareen, Kristin Maher, Dwight Barry, and Catherine Amlie-Lefond. "Anticoagulation for Septic Cerebral Venous Thrombosis in Childhood." Journal of Pediatric Hematology/Oncology 46, no. 8 (2024): 404–8. http://dx.doi.org/10.1097/mph.0000000000002949.

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Anticoagulation is recommended for most children with cerebral venous thrombosis (CVT) to prevent venous infarction and promote recanalization. An exception is CVT associated with head and neck infection (septic CVT), for which treatment of infection without concomitant use of anticoagulation is recommended. Despite this, the use of anticoagulation in septic CVT is controversial, and children with septic CVT are often anticoagulated due to concerns about thrombus progression and persistence despite infection treatment. A retrospective study of children with septic CVT cared for at Seattle Chil

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Botta, Ragasudha, Sheshagiri Donirpathi, Ravi Yadav, Girish B. Kulkarni, M. Veerendra Kumar, and Dindigur Nagaraja. "Headache Patterns in Cerebral Venous Sinus Thrombosis." Journal of Neurosciences in Rural Practice 08, S 01 (2017): S072—S077. http://dx.doi.org/10.4103/jnrp.jnrp_339_16.

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ABSTRACT Objectives: The objective of this study was to assess the clinical characteristics, patterns, and factors associated with headache in patients with cerebral venous sinus thrombosis (CVT). Methods: In this prospective cohort study, we recruited conscious CVT patients who were able to give reliable history after consent. Institutional ethics approval was obtained. The diagnosis of CVT was based on the clinical and imaging parameters. Data regarding headache characteristic, severity (visual analog scale [VAS]), imaging findings and outcome was recorded. Results: Forty-seven patients (19

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Lal, Darshan, Arunodaya R. Gujjar, Nandagopal Ramachandiran, et al. "Spectrum of Cerebral Venous Thrombosis in Oman." Sultan Qaboos University Medical Journal [SQUMJ] 18, no. 3 (2018): 329. http://dx.doi.org/10.18295/squmj.2018.18.03.011.

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Objectives: Cerebral venous thrombosis (CVT) can have varied and life-threatening manifestations. This study aimed to examine the spectrum of its clinical presentations and outcomes in a tertiary hospital in Oman. Methods: This retrospective study was conducted at the Sultan Qaboos University Hospital, Muscat, Oman, between January 2009 and December 2017. The medical records of all patients with CVT were reviewed to determine demographic characteristics, clinical features and patient outcomes. Results: A total of 30 patients had CVT. The mean age was 36.8 ± 11 years and the male-to-female rati

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Ferro, José M., Jonathan M. Coutinho, Olav Jansen, et al. "Dural Arteriovenous Fistulae After Cerebral Venous Thrombosis." Stroke 51, no. 11 (2020): 3344–47. http://dx.doi.org/10.1161/strokeaha.120.031235.

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Background and Purpose: This analysis examined the frequency of dural arteriovenous fistulae (dAVF) after cerebral venous thrombosis (CVT) in patients included in a randomized controlled trial comparing dabigatran etexilate with dose-adjusted warfarin (RE-SPECT CVT [A Clinical Trial Comparing Efficacy and Safety of Dabigatran Etexilate With Warfarin in Patients With Cerebral Venous and Dural Sinus Thrombosis]), who had systematic follow-up magnetic resonance (MR) imaging. Methods: RE-SPECT CVT was a Phase 3, prospective, randomized, parallel-group, open-label, multicenter, exploratory trial wi

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Riva, Nicoletta, and Walter Ageno. "Approach to thrombosis at unusual sites: Splanchnic and cerebral vein thrombosis." Vascular Medicine 22, no. 6 (2017): 529–40. http://dx.doi.org/10.1177/1358863x17734057.

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Splanchnic vein thrombosis (SVT) and cerebral vein thrombosis (CVT) are two manifestations of unusual site venous thromboembolism (VTE). SVT includes thrombosis in the portal, mesenteric or splenic veins, and the Budd–Chiari syndrome. CVT encompasses thrombosis of the dural venous sinuses and thrombosis of the cerebral veins. Unusual site VTE often represents a diagnostic and therapeutic challenge because of the heterogeneity in clinical presentation, the limited evidence available in the literature on the acute and long-term prognosis of these diseases, and the lack of large randomized contro

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Ng, Benjamin Han Sim. "Cerebral Venous Thrombosis: An Unusual Cause of Complex Ophthalmoplegia in an Elderly Man." Borneo Journal of Medical Sciences (BJMS) 15, no. 1 (2021): 45. http://dx.doi.org/10.51200/bjms.v15i1.1693.

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Cerebral venous thrombosis (CVT) is a neurological condition occurring because of thrombosis involving the cerebral venous sinuses. This case report is an unusual clinical manifestation of cerebral venous thrombosis in a 76-year-old Chinese man who presented with restricted eye movement and double vision. Despite extensive investigation, there was no better explanation for his clinical symptom and sign apart from cerebral venous thrombosis which was confirmed by magnetic resonance venography (MRV) of the brain. Once cerebral venous thrombosis was diagnosed, he was initiated on anticoagulation

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Lau, Kar Foo, Tsun-Haw Toh, Khairul Azmi Abdul Kadir, Mei-Ling Sharon Tai , and Kay Sin Tan. "Mechanical Thrombectomy for Life-Threatening Cerebral Venous Thrombosis: A Case Report." Case Reports in Neurology 12, Suppl. 1 (2020): 63–69. http://dx.doi.org/10.1159/000507343.

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Cerebral venous thrombosis (CVT) is a rare cause of stroke worldwide with a wide range of clinical presentations. Anticoagulation therapy has been regarded as the first line of management of CVT to prevent the progression of thrombosis and to re-establish the venous flow. We present a case of severe CVT who did not respond to conventional anticoagulation therapy but responded well to mechanical thrombectomy (MT). This report highlights the features of CVT to consider for early MT.

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Hosur, Bharat, Rahul Sinha, Narendra Kumar Jain, and B. A. Muthanna. "Isolated unilateral thalamic venous infarct in a toddler." BMJ Case Reports 15, no. 3 (2022): e249336. http://dx.doi.org/10.1136/bcr-2022-249336.

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Isolated deep cerebral venous thrombosis (CVT), especially involving only the right thalamus, is one of the rarest forms of intracranial venous thrombosis in a child. The anatomy and flow patterns of the deep cerebral venous system are complex and usually, the thrombosis of the internal cerebral veins (ICV) results in thalamic infarction bilaterally. The focal infections, thalamic tumours and vascular malformations may have overlapping clinicoradiological patterns. The treating team should be able to recognise the atypical phenotypes of the deep CVT at the earliest, which can facilitate apt tr

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Lindgren, Erik, Suzanne M. Silvis, Sini Hiltunen, et al. "Acute symptomatic seizures in cerebral venous thrombosis." Neurology 95, no. 12 (2020): e1706-e1715. http://dx.doi.org/10.1212/wnl.0000000000010577.

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ObjectiveTo identify characteristics, predictors, and outcomes of acute symptomatic seizures (ASS) in cerebral venous thrombosis (CVT), we investigated 1,281 consecutive adult patients with CVT included from 12 hospitals within the International CVT Consortium.MethodsWe defined ASS as any seizure between symptom onset and 7 days after diagnosis of CVT. We stratified ASS into prediagnosis and solely postdiagnosis ASS. Status epilepticus (SE) was also analyzed separately. We analyzed predictors for ASS and the association between ASS and clinical outcome (modified Rankin Scale) with multivariabl

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Rajoor, Umesh G., and Seema B. N. "Clinical profile of postpartum cerebral venous thrombosis." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 4 (2017): 1192. http://dx.doi.org/10.18203/2320-1770.ijrcog20170891.

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Background: Pregnancy and puerperium are most prevalent prothrombotic states leading to cerebral venous thrombosis (CVT). Pregnancy induces several changes in coagulation system, which persists at least during early puerperium, rendering it a prothrombotic state. The objective of the study was to study the clinical profile of postpartum CVT.Methods: A total of 32 consecutive patients admitted in medicine and obstetrics and gynecology ward between April 2012 and March 2015 with radiologically confirmed diagnosis of CVT were included in the study. Detailed history, clinical examination, and labo

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Mishra, Ashutosh Kumar, Ruchi Shukla, Archana Verma, and Rameswar Nath Chaurasia. "Cerebral venous thrombosis and the eye: the neuro-ophthalmology of cerebral venous blood clot." Nepal Journal of Neuroscience 21, no. 1 (2024): 9–13. http://dx.doi.org/10.3126/njn.v21i1.59342.

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Introduction: Cerebral venous thrombosis (CVT) is a form of venous thromboembolism which has varied clinical presentation. Ocular clinical features are quite common in CVT and may be the sole presenting feature and often tend to get misdiagnosed. This study was conducted to analyse clinical features especially neuro ophthalmological manifestations in CVT patients. Materials and Methods: In this prospective study 60 patients were enrolled in a study period of 3 years at tertiary care hospital. Follow up visits were performed at 1 month, 3 months, 6 months and 12 months after the initial diagnos

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Yang, Cheng, Huang Fang, Jun Hu, et al. "Clinical application of three-dimensional T1-weighted BrainVIEW in magnetic resonance imaging of cerebral venous thrombosis: a case report and literature review." Journal of International Medical Research 51, no. 4 (2023): 030006052311662. http://dx.doi.org/10.1177/03000605231166277.

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To date, there is no clinical scoring system or laboratory indicator that can rule out cerebral venous thrombosis (CVT) or provide diagnostic proof for evaluating post-treatment thrombosis recanalization during follow-up. We therefore explored an imaging method for quantitative assessment of CVT and assessed thrombotic changes during follow-up. A patient presented with severe posterior occipital distension extending to the top of the forehead and an elevated plasma D-dimer (DD2) level. Computed tomography and pre-contrast-enhanced magnetic resonance imaging revealed only a small amount of cere

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Sonia Josefa Fernandes, Suhariadi Atmanta, and Kusman Kusman. "Prosedur Pemeriksaan Digital Subtraction Angiography (DSA) Vena Cerebral Dengan Akses Transradial Pada Kasus Cerebral Venous Thrombosis (CVT)." Journal Innovation In Education 1, no. 4 (2023): 193–202. http://dx.doi.org/10.59841/inoved.v1i4.642.

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Background: Cerebral venous thrombosis (CVT) is a form of stroke when blood clots develop in the (venous sinus) of the brain. This condition causes the blood that flows into the brain to be unable to flow out. This can cause reduced blood flow to the brain and damage or kill brain cells if not treated properly. The research aims to determine the digital subtraction angiography (DSA) examination procedure of cerebral veins with trans-radial access in cases of cerebral venous thrombosis (CVT). Method: This type of research is qualitative research with a case study approach. Data was collected on

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Bajko, Zoltan, Anca Motataianu, Adina Stoian, et al. "Postpartum Cerebral Venous Thrombosis—A Single-Center Experience." Brain Sciences 11, no. 3 (2021): 327. http://dx.doi.org/10.3390/brainsci11030327.

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Background: Cerebral venous thrombosis (CVT) is a rare variant of stroke in the general population, but an important subtype among pregnancy- and puerperium-related cases. Studies describing its risk factors and clinical characteristics are limited. The aim of our study is to disclose these aspects and compare with cases unrelated to pregnancy and puerperium. Materials and Methods: We performed a retrospective analysis including 88 consecutive cases from a tertiary neurology clinic with a diagnosis of CVT. Ten of the 88 cases (11.3%) appeared during the postpartum period. Results: The mean age

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T., Aneesh, Hemamalini Gururaj, Arpitha J. S., Anusha Rao, Vaishnavi Chakravarthy, and Abhiman Shetty. "Clinical features, predisposing factors and radiological study of cerebral venous sinus thrombosis: experience from a tertiary care center in Southern India." International Journal of Research in Medical Sciences 5, no. 7 (2017): 3023. http://dx.doi.org/10.18203/2320-6012.ijrms20172981.

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Background: Cerebral venous thrombosis (CVT) is a less common cause of stroke with a wide range of clinical presentations, predisposing factors, radiological features and outcomes. A high index of suspicion is absolutely essential to diagnose cerebral venous thrombosis. In this article, we have reviewed the clinical spectrum and radiological profile of patients with cerebral venous thrombosis and attempted to identify the specific predisposing factors for developing cerebral venous thrombosis particularly in this region of India.Methods: 116 patients hospitalized from January 2015 to March 201

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Sawhney, Harpreet, Pranav Sharma, Priti Soin, Caitlin Pirreca, Dana Schwartz, and Puneet Singh Kochar. "Sonographic Diagnosis of Neonatal Cerebral Venous Sinus Thrombosis." Journal of Pediatric Neurology 18, no. 05 (2019): 236–40. http://dx.doi.org/10.1055/s-0039-1692216.

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AbstractCerebral venous thrombosis (CVT) is an uncommon but fatal disease in the pediatric age group, with a neonatal preponderance. The clinical presentation is nonspecific. Within the first 48 hours, the neonate usually presents with nonspecific signs such as respiratory distress, poor tone, and asphyxia. Neurological signs such as seizures, lethargy, apnea, and poor feeding set in later. We present the case of a neonatal CVT, presenting as asphyxia and respiratory depression on day 1 of life. CVT was diagnosed on neonatal cranial ultrasound. The patient died 3 days later.

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