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Journal articles on the topic 'Cervical precancerous lesions'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Sehnal, Borek, Tomáš Pichlík, Michael J. Halaška, et al. "The efficacy of human papillomavirus vaccination in the prevention of recurrence of severe cervical lesions." Česká gynekologie 88, no. 4 (2023): 294–300. http://dx.doi.org/10.48095/cccg2023294.

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Objective: A review of current knowledge on the efficacy of human papillomavirus (HPV) vaccination in preventing recurrent severe cervical lesions after excisional surgical treatment. Methods and results: HPV infection is necessary for the development of most cervical precancerous lesions and cervical cancers. Currently, three prophylactic vaccines against HPV infection are available on the market: bivalent Cervarix, quadrivalent Gardasil (formerly Silgard) and nonavalent Gardasil9. All three prophylactic vaccines show high effect in preventing the development of precancerous lesions. The high

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2

Mezhevitinova, E. A., P. R. Abakarova, and Y. S. Khlebkova. "PRECANCEROUS CERVICAL LESIONS." Medical Council, no. 12 (January 1, 2016): 112–18. http://dx.doi.org/10.21518/2079-701x-2016-12-112-118.

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Ephrem Dibisa, Keneni, Mengistu Tamiru Dinka, Lalisa Mekonen Moti, and Getahun Fetensa. "Precancerous Lesion of the Cervix and Associated Factors Among Women of West Wollega, West Ethiopia, 2022." Cancer Control 29 (January 2022): 107327482211179. http://dx.doi.org/10.1177/10732748221117900.

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Background Precancerous cervical lesion is an abnormality in the cells of the cervix that could eventually develop into cervical cancer. Cervical cancer is a public health problem that contributes to the death of women worldwide. In line with the high burden of the issue, the Ethiopian government had attempted to expand cervical cancer screening centers and recommendation of services to age-eligible as well as high-risk groups of women. Therefore, the study aimed to assess the prevalence of precancerous lesions of cervix cancer among women aged 30-49 years and associated factors in West Wolleg

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4

Beyene, Tesfalidet, Mohammed Akibu, Henok Bekele, and Wengelawit Seyoum. "Risk factors for precancerous cervical lesion among women screened for cervical cancer in south Ethiopia: Unmatched case-control study." PLOS ONE 16, no. 7 (2021): e0254663. http://dx.doi.org/10.1371/journal.pone.0254663.

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Background Nearly 90% of deaths from cervical cancer occur in a low resource setting. In Ethiopia, the magnitude of precancerous cervical lesions ranges from 7% to 28%. Precancerous cervical lesions may progress to cervical cancer. Early screening and treatment of precancerous cervical lesions is a cost-effective way to avert the growth of cervical cancer. However, there has been limited research on risk factors for precancerous cervical lesions in Ethiopia. Therefore, this study aimed to identify risk factors for precancerous cervical lesions among women screened for cervical cancer in south

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Winata, I. Gde Sastra, and Musa Taufiq. "Potential of trichloroacetic acid (TCA) for cervical precancerous lesions treatment in Indonesia." Majalah Obstetri & Ginekologi 30, no. 1 (2022): 48–51. http://dx.doi.org/10.20473/mog.v30i12022.48-51.

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HIGHLIGHTS 1. One of the most prevalent disease in females worldwide is cervical cancer.2. Simple and safe modality with high efficacy to treat cervical precancerous lesions before being progressed to cancer is necessary. 3. Trichloroacetic acid (TCA) has those advantages, so it will become an effective treatment for cervical precancerous lesions in the future. ABSTRACT Cervical cancer becomes one of the most prevalent disease in female worldwide. Human papillomavirus (HPV) is main etiology of cervical cancer, thus this disease is preventable. Before progressed into invasive cervical cancer, c

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Balan, Teodora Ana, Raluca Anca Balan, Demetra Socolov, et al. "Pregnancy-Related Precancerous Cervical Lesions: Pathogenesis, Diagnosis, Evolution, and Impact upon Gestation and Fertility." Journal of Clinical Medicine 13, no. 22 (2024): 6718. http://dx.doi.org/10.3390/jcm13226718.

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More common than cervical cancer, cervical intraepithelial neoplasia (CIN) represents a precursor lesion of cervical carcinoma, being associated with HPV infection. Due to the bidirectional relationship between HPV and estrogen and progesterone in pregnancy, most of the published data claim that precancerous lesions remain stable or even regress during pregnancy, although several studies have indicated the tendency of HSILs to persist. It is considered that pregnancy-related cervical precancerous lesions undergo a postpartum regression, due to stimulatory effects of the immune microenvironment

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Ansa, Meseret, and Tadios Mekonnen. "PREVALENCE OF VIA POSITIVE CERVICAL LESIONS AND DETERMINANT FACTORS AMONG WOMEN ATTENDING REGULAR GYNECOLOGY OUTPATIENT DEPARTMENT (RGOPD) AT SAINT PAUL’S HOSPITAL MILLENNIUM MEDICAL COLLEGE (SPHMMC)." Ethiopian Journal of Reproductive Health 10, no. 2 (2018): 11. http://dx.doi.org/10.69614/ejrh.v10i2.217.

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ABSTRACT BACKGROUND Cervical cancer is one of the leading causes of death for middle-aged women in the developing world. But it is a preventable disease by using relatively inexpensive technologies to detect abnormal cervical tissue before it progresses to invasive cervical cancer. In Ethiopia, the incidence of cervical cancer is 35.9 per 100,000 women. There is scarce data on prevalence of precancerous cervical lesions and the determinant factors in Ethiopia. OBJECTIVE The main objective of this study is to determine the prevalence of VIA positive precancerous cervical lesion among women atte

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8

Prima, Angga Trifianda, and Andi Friadi. "Gambaran Hasil HPV Test dengan PAP Test pada Pasien dengan Lesi Prakanker Serviks di RSUP Dr M Djamil Padang." JOURNAL OBGIN EMAS 2, no. 2 (2019): 83–86. http://dx.doi.org/10.25077/aoj.2.2.83-86.2018.

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Objective: To determine the description of the HPV Test results with the PAP Test in patients with cervical precancerous lesions at Dr. M. Djamil Padang.Methods: This study used a descriptive method with a sample of all patients with cervical precancerous lesions who had the HPV test and PAP test results in Dr. M. Djamil Padang from January 1, 2015 - December 31, 2017. Data were taken from the patient's medical records, including diagnosis, PAP test results using the Hybrid Capture (HC) method, and HPV test. Results: During the study period, 80 patients had PAP test results leading to precance

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9

Liu, Yuzhen, Chengcheng Cao, Peiling Zhai, and Youzhong Zhang. "Biological characteristics of cervical precancerous cell proliferation." Open Medicine 14, no. 1 (2019): 362–68. http://dx.doi.org/10.1515/med-2019-0036.

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AbstractHigh-grade squamous intraepithelial lesions (HSILs) are regarded as precancerous lesions that can progress to cervical carcinoma; however, it is very difficult to effectively differentiate these precancerous cells from cancerous cells based on morphology alone. Additionally, the difference between precancerous cells and cancerous cells in regard to biological behaviour remains unclear. We previously cultured primary normal uterine cervical keratinocytes from human normal cervical tissue and cervical precancerous cells that were naturally infected with human papillomavirus from small-si

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10

Budiana, I. Nyoman Gede, and Ida Bagus Rendra Kurniawan Artha. "Characteristics of Cervical Precancerous Lesions at a Tertiary Hospital in Bali, Indonesia." Indonesian Journal of Cancer 14, no. 4 (2020): 117. http://dx.doi.org/10.33371/ijoc.v14i4.731.

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Background: Cervical cancer is one of the biggest women’s health issues in developing countries including Indonesia. This study is aimed to describe the characteristics of cervical precancerous lesions at a tertiary hospital in Bali, Indonesia.Methods: This is a descriptive study using data from the medical records of patients with precancerous cervical lesions who attended the Gynecologic Oncology Outpatient Clinic Sanglah Hospital Denpasar, Bali, Indonesia, from January to December 2017. Results: There were 276 cases (2.88%) of the cervical precancerous lesion during the study period. The ma

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Memiah, Peter, Wangeci Mbuthia, Grace Kiiru, et al. "Prevalence and Risk Factors Associated with Precancerous Cervical Cancer Lesions among HIV-Infected Women in Resource-Limited Settings." AIDS Research and Treatment 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/953743.

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Objective. To assess the prevalence and identified associated risk factors for precancerous cervical cancer lesions among HIV-infected women in resource-limited settings in Kenya.Methods. HIV-infected women attending the ART clinic at the Nazareth Hospital ART clinic between June 2009 and September 2010. Multivariate logistic regression model with odds ratios and 95% confidence intervals (CI) were estimated after controlling for important covariates.Result. A total of 715 women were screened for cervical cancer. The median age of the participants was 40 years (range 18–69 years). The prevalenc

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Sladič, Mateja, Pepita Taneska, Branko Cvjetičanin, Mojca Velikonja, Vladimir Smrkolj, and Špela Smrkolj. "Cervical Intraepithelial Neoplasia Grade 3 in a HPV-Vaccinated Patient: A Case Report." Medicina 58, no. 3 (2022): 339. http://dx.doi.org/10.3390/medicina58030339.

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Persistent infection with human papillomavirus (HPV) causes almost all cervical precancerous lesions and cancers. Bivalent, quadrivalent, and nonavalent HPV vaccines effectively prevent high-grade cervical intraepithelial neoplasia (CIN3). The effectiveness of HPV vaccination against CIN3 is 97–100% in HPV-naïve populations and 44–61% in the overall population. Although HPV vaccination has substantially reduced the incidence of cervical cancers, several cases of precancerous cervical lesions in HPV-vaccinated patients have been reported. We report the clinical case of a 19-year-old woman whose

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Saniba, Verli, Wresnindyatsih, Zulkarnain Musa, and Zen Hafy. "Expression of HPV16 Oncoprotein E7 in Precancerous Lesions and Cervical Squamous Cell Carcinoma." Majalah Patologi Indonesia 29, no. 2 (2020): 57–64. http://dx.doi.org/10.55816/mpi.v29i2.409.

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BackgroundCervical cancer is the secondmost common malignancy in women worldwide.The vast majority of cervical cancersare associatedwith high risk HPV16 infection. The persistence of HPV16 and integration of viral DNA into cell genome are necessary for thedevelopment of precancerous lesion and squamous cell carcinoma (SCC) of the cervix. The integration of viral DNA in the host cellgenome resulted in the regulation of oncoprotein E7 leading to detection of HPV16 E7 expression in precancerous lesions and SCCof the cervix.The aim of this study was to evaluate differences of HPV16 E7 expression i

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Yu, Huan, Li Ma, Meilu Bian, Qian Li, and Haiyan Liang. "Association of abnormal vaginal microflora and HPV infection in cervical precancerous lesions: a retrospective study." Journal of Infection in Developing Countries 16, no. 06 (2022): 1089–95. http://dx.doi.org/10.3855/jidc.15961.

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Introduction: The aim of this study was to analyze the correlation between abnormal vaginal microflora and different types of human papillomavirus (HPV) infection and cervical precancerous lesions during the perimenopausal period. Methodology: This retrospective study included women patients who underwent liquid-based cytologic test (LBC), HPV test, leucorrhea routine test, or routine urine test at the China-Japan Friendship Hospital between October 2019 and January 2020. A cut-off of 45 years was used as the cut-off age for menopause. The positivity and subtypes of HPV were determined u

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15

Weldegebreal, Fitsum, and Teshager Worku. "Precancerous Cervical Lesion Among HIV-Positive Women in Sub-Saharan Africa: A Systematic Review and Meta-Analysis." Cancer Control 26, no. 1 (2019): 107327481984587. http://dx.doi.org/10.1177/1073274819845872.

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In sub-Saharan Africa, cervical cancer is an intersecting epidemic with HIV and it is the second most common cause of cancer-related deaths in women. Therefore, this study was aimed to estimate the current status of the prevalence and associated factors of precancerous cervical lesions among HIV-positive women in sub-Saharan Africa. A systematic literature search was conducted from legitimate electronic databases, including MEDLINE (Ovid), PubMed, EMBASE (Ovid), Emcare (Ovid), CINAHL (EBSCOhost), Web of Science, Scopus, and PopLine and other gray literature including Google, Google Scholar, Wo

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Varesano, Serena, Alessandra Pulliero, Emanuele Martorana, et al. "Screening of Precancerous Lesions in Women with Human Papillomavirus (HPV) Infection by Molecular Typing and MicroRNA Analysis." Journal of Personalized Medicine 13, no. 3 (2023): 531. http://dx.doi.org/10.3390/jpm13030531.

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Human papillomavirus (HPV) is causatively associated with cervical cancer, the fourth most common malignant disease of women worldwide: (1) The aim of the proposed study is to implement routine diagnostics of HPV precancerous cervical lesions by introducing new molecular diagnostic tools. (2) Methods: This is a retrospective cohort study with a total of twenty-two formalin-fixed paraffin-embedded (FFPE) cervical samples of various sample type (nine biopsy and thirteen conization) each patient had a previous abnormal results of pap test or HPV DNA test. Genotyping, viral load and co-infections

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17

Austin, Publishing Group. "Female Genital Schistosomiasis, a Neglected Differential of Cervical Precancerous and Cancerous Lesion: a Wakeup Call for on-Job Training for Healthcare Workers in Endemic Areas." Austin Journal of Clinical Case Reports 9, no. 1 (2022): 1241. https://doi.org/10.26420/austinjclincaserep.2022.1241.

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Abstract <strong>Background:</strong> Female genital schistosomiasis is a gynecological disease caused by <em>Schistosoma haematobium</em>. The uterine cervix appears to be the most affected area with most cases found in sub-Saharan Africa. Though both males and females can be affected, the consequences of genital schistosomiasis are more pronounced in females with reported increased risk of HIV transmission and malignancy of female genitalia. Female genital schistosomiasis of the cervix shares similarities in presentation to those of cervical intraepithelial neoplasm and sexual tran

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18

Saleh, Tareq, Nisreen Himsawi, Amani Al Rousan, et al. "Variable Expression of Oncogene-Induced Senescence/SASP Surrogates in HPV-Associated Precancerous Cervical Tissue." Current Issues in Molecular Biology 46, no. 12 (2024): 13696–712. https://doi.org/10.3390/cimb46120818.

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Oncogene-induced senescence (OIS) is a form of cellular senescence triggered by oncogenic signaling and, potentially, by infection with oncogenic viruses. The role of senescence, along with its associated secretory phenotype, in the development of cervical cancer remains unclear. Additionally, the expression of the senescence-associated secretory phenotype (SASP) has not yet been explored in cervical premalignant lesions infected by the Human Papilloma Virus (HPV). This study aimed to investigate the expression of OIS and SASP markers in HPV-infected cervical precancerous lesions. We used a se

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Messakop Moayeth Yannick, Bissay S.U, Mboua N.V, et al. "Precancerous lesions of the cervix: prevalence and associated risk factors in the city of Ebolowa." Journal of Science and Diseases 3, no. 2 (2025): 42–48. https://doi.org/10.64294/jsd.v3i2.90.

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Introduction: The prevalence of precancerous lesions of the cervix is increasing worldwide. The aim of our study was to determine associated risk factors of precancerous lesions of cervix in the city of Ebolowa. Methodology: This was a cross sectional analytical study conducted over a 3 years’ period from March 2021 to April 2024 at the Ebolowa Regional Health Center (ERHC). We included all records of women who had undergone cervical cancer screening at ERHC from March 2021 to April 2024. Date was collected using a previously tested and validated questionnaire. Descriptive analysis was done an

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Bumrungthai, Sureewan, Tipaya Ekalaksananan, Pilaiwan Kleebkaow, et al. "Mathematical Modelling of Cervical Precancerous Lesion Grade Risk Scores: Linear Regression Analysis of Cellular Protein Biomarkers and Human Papillomavirus E6/E7 RNA Staining Patterns." Diagnostics 13, no. 6 (2023): 1084. http://dx.doi.org/10.3390/diagnostics13061084.

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The current practice of determining histologic grade with a single molecular biomarker can facilitate differential diagnosis but cannot predict the risk of lesion progression. Cancer is caused by complex mechanisms, and no single biomarker can both make accurate diagnoses and predict progression risk. Modelling using multiple biomarkers can be used to derive scores for risk prediction. Mathematical models (MMs) may be capable of making predictions from biomarker data. Therefore, this study aimed to develop MM–based scores for predicting the risk of precancerous cervical lesion progression and

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Susman, Ed. "HPV Vaccine Prevents Precancerous Cervical Lesions." Oncology Times 26, no. 23 (2004): 13–14. http://dx.doi.org/10.1097/01.cot.0000291657.54738.60.

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22

Panjkovic, Milan, and Tatjana Ivkovic-Kapicl. "Angiogenesis in squamous precancerous cervical lesions." Vojnosanitetski pregled 64, no. 1 (2007): 7–11. http://dx.doi.org/10.2298/vsp0701007p.

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Background/Aim. Vascularisation is one of basic tumor's characteristics. Neoangiogenesis starts at the stage of the dysplastic epithelial changes, thus before the progression into invasive lesion. This study was designed to determine the relation between stromal angiogenesis and the grade of cervical intraepithelial changes (CIN). Methods. The tissue sections of 50 cone biopsies were immunohistochemically stained for CD31 antigen, a marker for endothelial cells. All microvessels along the basement membrane subtending dysplastic epithelium were counted. The mean microvessel count was calculated

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Wang, Yao, Yang Liu, Zhongyi Li, et al. "Association BetweenMALAT1andTHRILPolymorphisms and Precancerous Cervical Lesions." Genetic Testing and Molecular Biomarkers 22, no. 9 (2018): 509–17. http://dx.doi.org/10.1089/gtmb.2018.0097.

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Carlson, Kristen, Ina Pavlova, Tom Collier, Michael Descour, Michele Follen, and Rebecca Richards-Kortum. "Confocal microscopy: Imaging cervical precancerous lesions." Gynecologic Oncology 99, no. 3 (2005): S84—S88. http://dx.doi.org/10.1016/j.ygyno.2005.07.049.

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Mohammad, A. M., L. I. Azinfar, E. Johannesen, G. Yao, and M. I. Hunter. "Stromal imaging in precancerous cervical lesions." Gynecologic Oncology 159 (October 2020): 197–98. http://dx.doi.org/10.1016/j.ygyno.2020.05.312.

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Poudel, Anuj, and Prahar Dahal. "Cytohistological correlation of conventional Papanicolaou smears in cervical neoplasia at a tertiary care hospital of Nepal." Journal of Pathology of Nepal 9, no. 1 (2019): 1475–79. http://dx.doi.org/10.3126/jpn.v9i1.23372.

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Background: Conventional Cervical Cytology is the most widely used cervical cancer screening test. The incidence of cervical carcinoma is incredibly high in developing countries due to lack of proper knowledge. The extensive use of cervical screening with Papanicolau smears had considerably increased the detection of precancerous and cancerous lesion of uterine cervix. Study was conducted to evaluate cytohistological correlation and to calculate concordance and discordance of Pap smear in detection of precancerous and cancerous lesions of uterine cervix. Materials and Methods: A total of

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Arpita, Singh, Sharma Swaraj, Chandra Anju, Fahimuddin Mohd., and Kumar Navin. "Association of Cervical Non-Neoplastic, Precancerous and Neoplastic Lesion with Protein p16ink4a: A Prospective Observational Study." International Journal of Pharmaceutical and Clinical Research 15, no. 7 (2023): 803–8. https://doi.org/10.5281/zenodo.11660182.

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<strong>Background: </strong>p16<sup>INK4a </sup>(tumor-suppressor protein), used as biomarker of human papillomavirus (HPV) oncogenic activity have shown higher positivity rate in high grade cervical cancer lesions. <strong>Aims: </strong>The study aimed to assess association of cervical non-neoplastic, precancerous and neoplastic lesion with protein p16<sup>INK4a</sup>. <strong>Setting and Design: </strong>This study was hospital based prospective study. <strong>Methods and Material: </strong>The study was done among 110 patients in the department of P

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Ratnasari, Nur Venny, and Afnani Toyibah. "Relationship of Working Period in Tobacco Industry with Cervical Precancerous." Jurnal Berkala Epidemiologi 6, no. 1 (2018): 69. http://dx.doi.org/10.20473/jbe.v6i12018.69-76.

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Background: Cervical cancer prevalence ranks 7th globally and number 8th as the cause of death. Cervical cancer is ranked 2nd out of the 10 most cancers in Indonesia with an prevalence of 12,70%. Purpose: The aim of this research was to identify the relationship between females working period and the cervical precancerous lesions on female workers in “J” tobacco industry. Methods: This research was an analytical study using cross sectional design. The population of this research was female workers of "J" tobacco industry in Kepanjen Sub-District of Malang Regency in cigarette rolling and packi

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Venceslas Tarnju, Alemnju. "Human Papillomavirus and Precancerous Conditions of the Cervix- A Review." Cancer Research and Cellular Therapeutics 6, no. 3 (2022): 01–04. http://dx.doi.org/10.31579/2640-1053/112.

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Human papillomavirus (HPV) is present in precancerous conditions of the cervix. This review attempts to elucidate our understanding of precancerous cervical cancer, with particular emphasis on the central aetiologic function of persistent human papillomavirus (HPV) infection. The review dwells on recent studies that focused on detecting precancerous cervical lesions using visual inspection with acetic acid (VIA), convection cytology (Pap smear testing), and Schiller test. Anomalies in staining the exocervical epithelium and intraepithelial lesions upon detection with polymerize chain reaction

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Nagandla, Kavitha, Khaw Huang Lin, Ebenezer Chitra, and Mohamed Faiz Bin Mohamed Jamli. "Role of microRNAs as biomarkers of cervical carcinogenesis: a systematic review." Obstetrics & Gynecology Science 64, no. 5 (2021): 419–36. http://dx.doi.org/10.5468/ogs.21123.

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We performed a systematic review to identify the role of microRNAs (miRNAs) as biomarkers in the progression of cervical precancerous lesions. A comprehensive search of the Cochrane Controlled Register of Trials, PubMed, ScienceDirect, and Embase databases was performed for articles published between January 2010 and June 2020. The following Medical Subject Headings (MeSH) terms were searched: “microRNA” and “cervical” and “lesion.” All study designs that aimed to evaluate the correlation of miRNA expression with different precancerous cervical staging and/or cervical cancer were included, exc

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Claritha, Destiyana Cika, Chandra Dewi, and Shintia Christina. "HUBUNGAN ANTARA LESI PRAKANKER SERVIKS DENGAN SOSIODEMOGRAFI PEREMPUAN DI KECAMATAN LEGOK KABUPATEN TANGERANG TAHUN 2018." Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan 4, no. 1 (2020): 193. http://dx.doi.org/10.24912/jmstkik.v4i1.6321.

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Cervical and breast cancer are the highest prevalence cancer in Indonesia in 2013 which caused death to Indonesian women, cervical cancer by 0.8‰ and breast cancer by 0.5‰. Precancerous lesions of the cervix also known as cervical intraepithelial lesions (Cervical Intraepithelial Neoplastic) are the beginning of changes to cervical carcinoma. In general, precancerous lesions of the cervix originate from the squamous columnar junction in the uterine cervix, which undergoes the process of metaplasia. This study aims to determine whether there is a relationship between precancerous cervical lesio

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Prasetyo, Rizki Eko, Gondo Mastutik, and Sjahjenny Mustokoweni. "PREVALENCE OF HUMAN PAPILLOMAVIRUS GENOTYPES IN LOW AND HIGH GRADE SQUAMOUS INTRAEPITHELIAL LESIONS AT CERVICAL TISSUE." Folia Medica Indonesiana 53, no. 4 (2017): 258. http://dx.doi.org/10.20473/fmi.v53i4.7157.

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HPV infection is known to cause cervical cancer. This study aimed to identify the variant of HPV genotypes of cervical precancerous lesions from low grade squamous intraepithelial lesion (LSIL) and high grade squamous intraepithelial lesion (HSIL). This was an explorative study using formalin fix paraffin embedded (FFPE) from cervical precancerous lesions at Dr. Soetomo Hospital, Surabaya. DNA was extracted from FFPE and hybridized for HPV genotyping using Ampliquality HPV Type Express kit (AB ANALITICA) by reverse line blot techniques. The results showed that there were variants of HPV genoty

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Modinou, Olga, Lykourgos Liaropoulos, Dafni Kaitelidou, kyriakos Kioulafas, and Eleni-Maria Theodoraki. "Management of Precancerous Lesions of the Uterine Cervix according to Demographic Data." ISRN Obstetrics and Gynecology 2011 (October 27, 2011): 1–6. http://dx.doi.org/10.5402/2011/301680.

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Aims. Worldwide, cervical cancer is the fifth most deadly cancer in women, but screening prevents cancer by detecting precancerous lesions. The purpose of this study is to present the treatment profile for precancerous lesions of the uterine cervix, according to demographic data. Methods. An annual retrospective study was conducted in two public primary health care centres in Greece. The total number of Pap smears and colposcopies performed as well as the management of women with cervical intraepithelial neoplasia was collected and analysed. Results. Demographic characteristics and correlation

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Woromogo, Sylvain Honore, Nathalie Ambounda Ledaga, Felicite Emma Yagata-Moussa, and Astride Smeige Mihindou. "Uterine cervical neoplasms mass screening at the University Hospital Centre of Libreville, Gabon: Associated factors with precancerous and cancerous lesions." PLOS ONE 16, no. 7 (2021): e0255289. http://dx.doi.org/10.1371/journal.pone.0255289.

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The objectives of this study were to identify the associated factors with cancerous and precancerous lesions of cervix. In Africa, the incidence of uterine cervical neoplasms varies from one region to another, where most women with uterine cervical neoplasms are seen at an advanced stage. For this reason, uterine cervical neoplasms mass screening reduces the incidence and mortality due to this disease, similar to what is being done in Europe. A cross-sectional analytical study was conducted. Socio-demographic characteristics, gynaecological-obstetrical history, risk factors, data from visual i

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Chambuso, Ramadhani S., Stephen Shadrack, Salum J. Lidenge, Ntoli Mwakibete, and Rui M. Medeiros. "Influence of HIV/AIDS on Cervical Cancer: A Retrospective Study From Tanzania." Journal of Global Oncology 3, no. 1 (2017): 72–78. http://dx.doi.org/10.1200/jgo.2015.002964.

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Purpose Cervical cancer is the leading cause of cancer-related morbidity and mortality in women in Tanzania. Any impact of the HIV/AIDS epidemic on cervical precancerous lesions and invasive cervical cancer has a significant implication, as for any public health concern, especially in an area such as the Morogoro region in Tanzania, which has one of the highest rates of cervical cancer in the world. Methods A comparative retrospective study was performed of 536 women screened for cervical cancer by visual inspection methods at the Morogoro Regional Referral Hospital over a period of 3 years; t

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Jha, A., and AK Chaurasia. "A retrospective analysis of cervical smears for detection of precancerous lesions." Journal of Pathology of Nepal 5, no. 10 (2015): 847–49. http://dx.doi.org/10.3126/jpn.v5i10.15641.

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Background: Diseases of the cervix are common in women. Detection of neoplastic lesions is of prime importance in the evaluation of cervical smears although their frequency is less than the non-neoplastic conditions. Reactive and inflammatory conditions, however, may mimic or obscure the dysplastic changes. The aim of this study was to evaluate the frequencies of various inflammatory, reactive and neoplastic lesions in the cervical smears.Materials and Methods: This was a retrospective study of 150 cases of cervical smears collected from medical record section of the hospital and Department of

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Vargas, Sara, Maria Pulido Valente, Margarida Mendes de Almeida, Joaquim Neves, and Carlos Calhaz-Jorge. "Isolated Non-16/18 High-Risk Human Papillomavirus Cervical Infection: Re-Evaluation After One Year." Acta Médica Portuguesa 32, no. 9 (2019): 588. http://dx.doi.org/10.20344/amp.10183.

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Introduction: High-risk human papillomavirus cervical infection is currently a well-established cause of cervical cancer. However, only a few women with persistent infections will develop cervical precancerous and malignant lesions. Approximately 20% of all cervical cancers are attributable to non-16/18 serotypes. This study aims to evaluate the results of our clinical approach to women with this infection.Material and Methods: We conducted an observational and prospective study from September 2012 to September 2017, which included women with isolated non-16/18 high-risk human papillomavirus i

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Wang, Yan, and Mindan Xu. "Analysis of the Clinical Application Value of Colposcopy Biopsy in the Screening of Cervical Precancerous Lesions." Advances in Obstetrics and Gynecology Research 1, no. 2 (2023): 8–13. http://dx.doi.org/10.26689/aogr.v1i2.5180.

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Objective: To analyze the value of colposcopy biopsy in the screening of cervical precancerous lesions. Methods: 5,000 patients with suspected cervical precancerous lesions were used as samples. From January 2020 to December 2022, pathological examination and colposcopy biopsy were carried out, and the value of colposcopy biopsy was analyzed. Results: 1,503 cases were positive and 3,497 cases were negative by pathology, whereas 1,432 cases were positive and 3,568 cases were negative by colposcopy biopsy. The diagnostic sensitivity, specificity, and accuracy of colposcopy biopsy were 99.69%, 94

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Pleş, Liana, Julia-Carolina Radosa, Romina-Marina Sima, Radu Chicea, Octavian-Gabriel Olaru, and Mircea-Octavian Poenaru. "The Accuracy of Cytology, Colposcopy and Pathology in Evaluating Precancerous Cervical Lesions." Diagnostics 12, no. 8 (2022): 1947. http://dx.doi.org/10.3390/diagnostics12081947.

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Introduction: Cervical cancer (CC) is the third most common cancer in the world, and Romania has the highest incidence of cervical cancer in Europe. The aim of this study was to evaluate the correlation between cytology, colposcopy, and pathology for the early detection of premalignant cervical lesions in a group of Romanian patients. Methods: This observational type 2 cohort study included 128 women from our unit, “Bucur” Maternity, who were referred for cervical cancer screening. Age, clinical diagnosis, cytology results, colposcopy impression, and biopsy results were considered. Colposcopy

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Buiu, Cătălin, Vlad-Rareş Dănăilă, and Cristina Nicoleta Răduţă. "MobileNetV2 Ensemble for Cervical Precancerous Lesions Classification." Processes 8, no. 5 (2020): 595. http://dx.doi.org/10.3390/pr8050595.

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Women’s cancers remain a major challenge for many health systems. Between 1991 and 2017, the death rate for all major cancers fell continuously in the United States, excluding uterine cervix and uterine corpus cancers. Together with HPV (Human Papillomavirus) testing and cytology, colposcopy has played a central role in cervical cancer screening. This medical procedure allows physicians to view the cervix at a magnification of up to 10%. This paper presents an automated colposcopy image analysis framework for the classification of precancerous and cancerous lesions of the uterine cervix. This

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Van Arsdale, A. R., J. Lenz, M. H. Einstein, and C. Montagna. "Mapping HPV integration in precancerous cervical lesions." Gynecologic Oncology 145 (June 2017): 31–32. http://dx.doi.org/10.1016/j.ygyno.2017.03.084.

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Raffone, Antonio, Antonio Travaglino, Antonio D'Antonio, et al. "Immunohistochemistry for BAG3 in cervical precancerous lesions." Acta Obstetricia et Gynecologica Scandinavica 99, no. 2 (2019): 295–96. http://dx.doi.org/10.1111/aogs.13754.

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Auer, Melinda S., and David G. Mutch. "Diagnosis and Management of Precancerous Cervical Lesions." Current Obstetrics and Gynecology Reports 3, no. 2 (2014): 128–35. http://dx.doi.org/10.1007/s13669-014-0083-x.

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Zhao, Na, Yan Gao, Fang Li, Jingtian Shi, Yanni Huang, and Hongyun Ma. "Detection of precancerous lesions in cervical images of perimenopausal women using U-net deep learning." African Journal of Reproductive Health 29, no. 4 (2025): 108–19. https://doi.org/10.29063/ajrh2025/v29i4.10.

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Due to physiological changes during the perimenopausal period, the morphology of cervical cells undergoes certain alterations. Accurate cell image segmentation and lesion identification are of great significance for the early detection of precancerous lesions. Traditional detection methods may have certain limitations, thereby creating an urgent need for the development of more effective models. This study aimed to develop a highly efficient and accurate cervical cell image segmentation and recognition model to enhance the detection of precancerous lesions in perimenopausal women. based on U-s

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Manguilla, Maryse N. Akolbout, Maryse N. Akolbout Manguilla, and Fabien Mouamba. "Cytological Aspects of Cervico-Uterine Smears from HIV/HPV HR Coinfected Women Treated with Antiretrovirals." International Journal of Health Sciences and Research 14, no. 2 (2024): 262–70. http://dx.doi.org/10.52403/ijhsr.20240235.

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Introduction: Women living with HIV are at high risk of developing persistent HPV-HR infections. This favors the development of precancerous lesions that may progress to cervical cancer. With a view to improving management and taking preventive action against cervical lesions and cervical cancer in women living with HIV, our study aimed to describe cervical abnormalities and establish a relationship between lesion severity and HPV-HR genotypes in HIV/HPV-HR co-infected women. Methodology: This was a descriptive cross-sectional study conducted at the CTAB from March 2021-December 2022. Of 122 w

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Tirkaso, Birhanu Hailu, Tesfaye Hurgesa Bayisa, and Tewodros Wubshet Desta. "Histopathologic patterns and factors associated with cervical lesions at Jimma Medical Center, Jimma, Southwest Ethiopia: A two-year cross-sectional study." PLOS ONE 19, no. 4 (2024): e0301559. http://dx.doi.org/10.1371/journal.pone.0301559.

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Background The cervix is the lower portion of the uterus, which connects this organ to the vagina through the endocervical canal. Objective This study aimed to determine the histopathologic patterns and factors associated with cervical lesions at Jimma Medical Center from September 12, 2017, to September 12, 2019. Methods A 2-year facility-based cross-sectional study was conducted from May 1 to June 30, 2020. Result In this study, cervical cancer was the most common (71%) cause of cervical lesions. Squamous cell carcinoma was the most frequent cervical cancer diagnosed during the study, accoun

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Rakar, Stelio, Mojca Eržen, and Andrej Možina. "Treatment of precancerous cervival lesions and early stage cervical cancer." Kolposkopia 1, no. 4 (2002): 163–67. http://dx.doi.org/10.1066/s10014010112.

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Farras, Dinta Ayuda, Lintang Dian Saraswati, Praba Ginandjar, and Arie Wuryanto. "RISK OF PRECANCEROUS CERVICAL LESIONS A DESCRIPTIVE STUDY AT SAPURAN HEALTH CENTER, WONOSOBO CITY." Journal of Public Health for Tropical and Coastal Region 3, no. 1 (2020): 23–27. http://dx.doi.org/10.14710/jphtcr.v3i1.8402.

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Cervical cancer is a disease that attacks women caused by Human Paplilloma Virus. Early sign of this cancer is discovery precancerous cervical lesions. Early prevention of knowing the presence of these lesionss is by early detection of the Visual Inspection Acetic Acid (VIA) method. This study was an observational research using case control design. Samples were taken is 126 people, 63 people as total cases and 63 peoples as control. using simple random sampling. Univariate data analyzed and presented in frequency distribution. Characteristics of respondents in this study include the majority

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Macdonald, Mr Dike, Omotoso J. Ayodele, Odusolu Patience, et al. "Disparity in the incidence, prevalence, etiology, screening and presentation of cervical cancer between Africa and America." Obstetrics & Gynecology International Journal 12, no. 4 (2021): 212–16. http://dx.doi.org/10.15406/ogij.2021.12.00579.

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Cervical cancer represents a huge burden of non-infectious disease globally. It is the fourth most common cancer in women and accounts for over half a million deaths every year. In low and middle income countries (LMIC) it is the second most common cancer among women closely following breast cancer. The aetiological agent implicated in this disease is the human Papillomavirus. The high-risk human papilloma virus (HPV) has been mostly implicated. Worldwide, the most common high-risk human papillomavirus implicated in cervical cancer are type 16 and 18. The viral infection of the uterine cervica

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Jin, Long-Mei, Ling Xu, Jun Xu, et al. "Effects of Information Technology–Based Two-Way Referral on Diagnosis and Management of Cervical Lesions: A Cluster-Controlled Trial in China." Asia Pacific Journal of Public Health 30, no. 5 (2018): 491–99. http://dx.doi.org/10.1177/1010539518786635.

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This study investigates the effectiveness of information technology–based 2-way referral in the diagnosis and management of cervical lesions in Minhang District, Shanghai, China. Women who underwent screening for cervical lesions in 4 community health centers constituted the intervention group, whereas women from the other 9 community health centers were included as controls. The diagnosis rate of cervical lesions was higher in the intervention group (7.61%) than in the control group (0.36%; P = .000). The diagnosis rate of early cervical lesion was 97.11% in the intervention group and 85.71%

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