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1

Blaha, Jakub. "Výpočtová analýza zbytkových napětí u autofretovaných vysokotlakých zásobníků paliva." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2015. http://www.nusl.cz/ntk/nusl-231712.

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The master‘s thesis is aimed on numerical simulation of autofrettage of high pressure fuel vessel – rail in Common Rail system. First there is described Chaboche model, which is later used for simulation of autofrettage. There are described different approaches which can be used to obtain sufficient material model. Then there is observed influence of these different approaches on stress state of rail within the process of autofrettage. Suitability of Chaboche model for autofrettage and re-autofrettage simulations is assessed by comparing with more complex Jiang model. In the end there is a stu
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2

Paraska, Boris. "Studie vlivu složitosti Chabocheho modelu plasticity na napjatost a deformaci u vysokotlaké nádoby." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2014. http://www.nusl.cz/ntk/nusl-231183.

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The main aim of this thesis is to define material parameters of Chaboche model of plasticity. Adjustment of the parameters has to correspond to the experimental datas. These datas are represented by an uniaxial strain controlled test curve for fewer than two cycles and also by cyclic stress-strain curve. After that, an cyclic tension-compresion test for various parameters of Chaboche´s model of plasticity is simulated in an ANSYS software. Finally, the most suitable configuration of Chaboche´s model of plasticity is used for cylindrical thick-walled body. Cylindrical body represents a simplifi
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3

Tanbakuei, Kashani Majid. "Effect of Forming Process on the Deformational Behaviour of Steel Pipes." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/35914.

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Buried pipeline networks play a vital role in the transportation of oil and natural gas from centers of production to centers of consumption. A common manufacturing technique for such pipes is the UOE process, where a flat steel plate is first formed into a U shape, then into an O shape, welded at the seam, and mechanically expanded before being shipped on site. The UOE forming process deforms the pipe material plastically and induces residual strains in the pipe. Such pipes are commonly buried on side and then are pressurized under the high head of the fluids they convey which induce hoop st
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4

Djimli, Lynda. "Analyse du phénomène de rochet : essais et modélisation." Phd thesis, INSA de Rouen, 2010. http://tel.archives-ouvertes.fr/tel-00583729.

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Cette thèse s'inscrit dans le contexte de l'étude de l'effet de l'identification des paramètres matériau sur la prévision du comportement cyclique. Une étude de l'effet de la pré-déformation sur la réponse du matériau vis à vis le rochet est aussi présentée. Pour cela deux types d'expériences ont été menés au sein de l'équipe Mécanique du Groupe de Physique des Matériaux (GPM, UMR 6634) à l'INSA de Rouen sur un acier inoxydable de type 304L : Les essais EXP1 contenant des essais à déformation imposée axiale et multiaxiale et des essais de rochet en une et deux phases. Ces essais sont tirés de
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5

Sehnal, Dominik. "Nízkocyklová životnost v podmínkách jaderné energetiky." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-399581.

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Fatique life extension of nuclear powerplants lies in the search for project reserves. This work deals with the evaluation of low-cycle fatigue of nuclear installations of the VVER type and the assessment of the influence of the computational model level. Fatigue tests of austenitic steel using optical method of digital image correlation for which the evaluation procedure is designed and used is performed. Selected model of plasticity with kimenatic (Chaboche) and combinated hardening (Chaboche, Voce) are calibrated from the obtained data. Subsequently, the durability of the test specimen is d
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6

Rosenblad, Louise, and Filippa Hallbäck. "Low Cycle Fatigue Weld Optimization using Chaboche Material Model." Thesis, KTH, Hållfasthetslära (Avd.), 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-232520.

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In this master thesis a method for optimizing welds has been investigated. The method was developed by the use of a finite element (FE)-model of a silencer. The silencer is exposed to both dynamic and thermal loads. Focus has been on using topology optimization for the welds. The main driver for developing a method for weld optimization is to investigate whether the stresses close to the welds could be decreased if some weld material were to be removed. Another motive for conducting the study is to understand the potential for decreased computation time for modeling welds (continuous welds) sho
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7

Avanzi, Ariel. "Biophysical model of synaptic plasticity." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amslaurea.unibo.it/21967/.

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Nel 1982 Elie Bienestock, Leon Cooper e Paul Munro scrissero ”Theory for the development of neuron selectivity” proponendo uno schema di evoluzione sinaptica nel quale competono i modelli in arrivo piuttosto che la convergenza degli afferenti. Brevemente divenne nota come teoria BCM e fu il trampolino di lancio per ulteriori lavori sulla modificazione delle sinapsi corticali. Durante le ultime due decadi sono state fatte nuove formulazioni, come la IBCM di Nathan Intrator e Leon Cooper del 1992, e nuovi metodi sono stati introdotti permettendo la creazione di reti neurali più complicate ed e
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8

Wohlgemuth, Jens. "Study of a model for reference-free plasticity." Doctoral thesis, Universitätsbibliothek Leipzig, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-113290.

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In meiner Doktorarbeit untersuche ich ein Kac-artiges Vielteilchen-Modell, das eine Beschreibung von plastischen Verformungen ohne Verwendung einer Referenz-Konfiguration ermöglicht. Im Rahmen des Modells wird die Verformung eines Körpers durch Angabe von Atompositionen beschrieben. Es wird eine Mesoskala zwischen der Mikroskala der Atom-Atom Abstände und der Makroskala des Körpers eingeführt. Um jeden Punkt wird die Konfiguration auf dieser Mesoscala mit einem Bravais-Gitters approximiert. Die Matrix, die dieses Gitter aufspannt, wird als Argument eines elastischen Energiefunktionals verwende
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9

Yeung, Luk Chong. "A mechanistic model of calcium-dependent synaptic plasticity /." View online version; access limited to Brown University users, 2005. http://wwwlib.umi.com/dissertations/fullcit/3174704.

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10

Arnold, F. J. L. "An experimental model of transcription-dependent synaptic plasticity." Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596164.

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A cell culture system was developed to study synaptic plasticity. Electrical activity across cultured hippocampal networks was monitored using an array of 60 microelectrodes (MEA). These networks demonstrated spontaneous low rate asynchronous electrical activity. the GABA-A receptor antagonist bicuculline (50μM) transformed this activity into synchronous repetitive bursts of action potentials across the network, accompanied by NMDA receptor-dependent sustained global calcium transients. A 15 minute bicuculline exposure induced a long-lasting increase in synaptic efficacy, and a dramatic change
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11

Triggs, Alison Mary. "Plasticity in immune responses in a model insect." Thesis, Queen Mary, University of London, 2011. http://qmro.qmul.ac.uk/xmlui/handle/123456789/1280.

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In order to understand how the environment, parental environment and inbreeding influence immune function and life history traits, I carried out a series of experiments using the Indian meal moth, Plodia interpunctella, as a model organism. Past studies have focused mainly on one aspect of environmental fluctuation at a time, so, to study the nature of the interactions between environmental variables in determining immunity, temperature, food quality and density were all varied together. There were interaction effects on immunity between all three environmental variables. The effect of density
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12

Ciavaglia, Francesca. "A bounding surface plasticity model for anisotropic soils." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.535195.

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13

Trommershäuser, Julia. "A semi-microscopic model of synaptic transmission and plasticity." [S.l.] : [s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=963474626.

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14

Tahar, Benabdellah. "C←2 continuous hardening/softening elasto-plasticity model for concrete." Thesis, University of Sheffield, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323061.

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15

Alankar, Alankar. "Development of a 3D microstructure sensitive crystal plasticity model for aluminum." Pullman, Wash. : Washington State University, 2010. http://www.dissertations.wsu.edu/Dissertations/Spring2010/A_Alankar_020910.pdf.

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16

Babu, Bijish. "Physically based model for plasticity and creep of Ti-6Al-4V /." Luleå : Division of Material Mechanics, Luleå University of Technology, 2008. http://epubl.ltu.se/1402-1757/2008/40/.

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17

White, Charles Samuel. "A combined isotropic-kinematic hardening model for large deformation metal plasticity." Thesis, Massachusetts Institute of Technology, 1988. http://hdl.handle.net/1721.1/14400.

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18

Dondeti, Piyush Prashant. "Rate-Dependent Homogenization based Continuum Plasticity Damage Model for Dendritic Cast Aluminum Alloys." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1308245866.

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19

Seidalinov, Gaziz. "A simple anisotropic bounding surface plasticity model for cyclic response of clays." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/43501.

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Natural clays are anisotropic in their in-situ state and have an undisturbed shear strength in excess of the remoulded strength. In addition, most of the structures founded on clay deposits must be designed to withstand cyclic loads such as seismic ground motions or ocean waves. When subjected to earthquake or wind induced cyclic loadings, clay exhibits complex response. A realistic modeling of clay response under irregular cyclic loading requires an appropriate description of the stress{strain relationship. This thesis extends the formulation of a Simple ANIsotropic CLAY plasticity (SANICLAY)
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20

Gomez, Rodolfo Andres. "Monotonic Plasticity-Damage and Fatigue Life Model Correlations on AISI 4140 Steel." MSSTATE, 2007. http://sun.library.msstate.edu/ETD-db/theses/available/etd-07052007-144738/.

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A microstructure-based plasticity-damage model is used to predict the mechanical behavior of commercially available AISI 4140 steel. Monotonic tension, compression and torsion tests were performed to obtain the set of plasticity and damage constants required for model calibration. Then, tension tests on Bridgman notched specimens were undertaken to study the damage-triaxiality dependence. Three different notch radii generated different levels of triaxiality at the notch. The modeled triaxiality-damage correlation was validated with SEM fracture surface analysis. Stress-strain correlations unde
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21

McKellar, Dougan Kelk. "A dislocation model of plasticity with particular application to fatigue crack closure." Thesis, University of Oxford, 2001. http://ora.ox.ac.uk/objects/uuid:45183b90-017f-4ac1-9550-94772a0ca88b.

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The ability to predict fatigue crack growth rates is essential in safety critical systems. The discovery of fatigue crack closure in 1970 caused a flourish of research in attempts to simulate this behaviour, which crucially affects crack growth rates. Historically, crack tip plasticity models have been based on one-dimensional rays of plasticity emanating from the crack tip, either co-linear with the crack (for the case of plane stress), or at a chosen angle in the plane of analysis (for plane strain). In this thesis, one such model for plane stress, developed to predict fatigue crack closure,
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22

Askari, Peyman. "A sense of place : a model of synaptic plasticity in the hippocampus." Thesis, University of Southampton, 2013. https://eprints.soton.ac.uk/352322/.

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Artificial synaptic plasticity is a programming approach used in artificial neural simulations to replicate the change in efficacy between two synapses observed in biological neurons. This biological synaptic plasticity is thought to enable neurons to control the connections between them. This control is then thought to lead to complex behaviour such as path integration. This stochastic process of activity dependent biological synaptic plasticity forces groups of neurons to operate together. The operation of large subsets of neurons underlies the cognition and memory formation in animals, with
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23

Mahmoody, Sam. "Micromechancal modeling of dual-phase steel using a rate-dependent crystal plasticity model." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=99778.

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Dual-phase (DP) steels consisting of a ferrite matrix with dispersed martensite particles have attracted a significant interest due to their combination of high work hardening and ductility. A great deal of experimental work has been done to obtain a better comprehension of the relation of their mechanical behaviour to their microstructural characteristics. In the present work, a micromechanical study of ferrite-martensite DP steels is conducted. The deformation of ferrite is described by a rate-dependent crystal plasticity theory, which relates the stress-strain field equations on the grain l
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24

Wu, Kun. "Long-lasting hippocampal plasticity in the kainic acid model of temporal lobe epilepsy." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0016/NQ58194.pdf.

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25

LeBlanc, Jocelyn Jacqueline. "Critical period plasticity and sensory function in a neuroligin-3 model of autism." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:10820.

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Extensive experience-dependent refinement of cortical circuits is restricted to critical periods of plasticity early in life. The timing of these critical periods is tightly regulated by the relative levels of excitatory and inhibitory (E/I) neurotransmission during development. Genetic disruption of synaptic proteins that normally maintain E/I balance can result in severe behavioral dysfunction in neurodevelopmental disorders like autism, but the mechanisms are unclear. We propose that abnormal critical periods of sensory circuit refinement could represent a key link between E/I imbalance and
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26

HASHMI, QUAZI SARWAR EHSAN. "NONASSOCIATIVE PLASTICITY MODEL FOR COHESIONLESS MATERIALS AND ITS IMPLEMENTATION IN SOIL-STRUCTURE INTERACTION." Diss., The University of Arizona, 1987. http://hdl.handle.net/10150/184024.

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A constitutive model based on rate-independent elastoplasticity concepts is developed and used to simulate the behavior of geologic materials under arbitrary three-dimensional stress paths. The model accounts for various factors such as friction, stress path and stress history that influence the behavior of geologic materials. A hierarchical approach is adopted whereby models of progressively increasing sophistication are developed from a basic isotropic-hardening associative model. Nonassociativeness is introduced as correction or perturbation to the basic model. Deviation of normality of the
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27

Otoshi, Chad Kuniyuki. "Receptor plasticity in the lumbar spinal cord a move to a simpler model /." Diss., Restricted to subscribing institutions, 2008. http://proquest.umi.com/pqdweb?did=1679374141&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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28

Gandhi, Reno. "Hippocampal Synaptic Plasticity in a Murine Knock-Out Model of Fragile X Syndrome." Thesis, Université d'Ottawa / University of Ottawa, 2014. http://hdl.handle.net/10393/31610.

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The dissertation is divided into two separate experiments that explore the effects of visual-spatial learning on PSD-95 dorsal hippocampal expression. Specifically, the aim of these studies was to explore the effect of learning an assay, the Hebb-Williams mazes, on the protein expression of PSD-95 in Fmr1 KO mice. PSD-95 is an important scaffolding protein hypothesized to be involved in learning and memory. In cellular models of Fragile X Syndrome it has been shown to be dysregulated but it has never been measured following behavioural learning. Establishment of a deficit using an ecologically
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Li, Xiaoshuang. "Identification and Phenotypic Plasticity of Metastatic Cells in a Mouse Model of Melanoma." FIU Digital Commons, 2017. http://digitalcommons.fiu.edu/etd/3472.

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Melanoma is the deadliest form of skin cancer due to its high propensity to metastasize and resistance to current therapies. We have created a spontaneous mouse model of metastatic melanoma (Dct-Grm1/K5-Edn3) where metastasis to the lungs is 80% penetrant. The primary tumors of these mice present cellular heterogeneity with cells at varying levels of differentiation. The main goal of this study was to determine the metastatic potential of the primary tumor resident Tyrosinase positive cells and evaluate the dynamic phenotypic changes as those cells move from the primary tumors to the sites of
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Corre, Grégoire. "Enriched elasto-plastic beam model." Thesis, Paris Est, 2018. http://www.theses.fr/2018PESC1031/document.

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Ce travail s'inscrit dans le cadre d'un partenariat scientifique entre le Laboratoire Navier et la société STRAINS. Convaincue du besoin de renouveler les méthodes actuelles de calcul de structures, STRAINS développe un nouveau logiciel dédié à l'analyse des ouvrages d'art. Dans ce contexte, cette thèse propose de nouveaux outils pour l'analyse des structures élancées. Le modèle élastique de poutre d'ordre supérieur développé par cite{Ferradi2016} est d'abord adapté au cas des déformations imposées, permettant ainsi au modèle de représenter un grand nombre de phénomènes physiques tels que le f
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Franklin, Francis James. "Modelling mild wear." Thesis, University of Sheffield, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312780.

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32

Graupner, Michael. "Induction and Maintenance of Synaptic Plasticity." Doctoral thesis, Technische Universität Dresden, 2007. https://tud.qucosa.de/id/qucosa%3A23857.

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Synaptic long-term modifications following neuronal activation are believed to be at the origin of learning and long-term memory. Recent experiments suggest that these long-term synaptic changes are all-or-none switch-like events between discrete states of a single synapse. The biochemical network involving calcium/calmodulin-dependent protein kinase II (CaMKII) and its regulating protein signaling cascade has been hypothesized to durably maintain the synaptic state in form of a bistable switch. Furthermore, it has been shown experimentally that CaMKII and associated proteins such as protein k
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33

Eadie, Brennan Daniel. "Neuronal plasticity in the dentate gyrus of a mouse model of Fragile X syndrome." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/25031.

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Fragile-X syndrome (FXS) is the most common form of inherited intellectual disability (ID), representing a considerable burden of health in our society. FXS is caused by repression of the transcription of one gene, Fmr1. Normally, expression of the Fmr1 gene leads to the production of one type of protein, the Fragile-X Mental Retardation Protein (FMRP). At the cellular level, FXS is caused by a lack of FMRP. The fact that mice and humans possess a nearly identical Fmr1 gene has permitted the generation of a mouse model of FXS using modern transgenesis techniques (Fmr1 knockout (KO) mice).
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Bartsch, Armin P. "Orientation maps in primary visual cortex a Hebbian model of intracortical and geniculocortical plasticity /." [S.l. : s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=962125733.

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35

Newman, Danielle. "Plasticity in the direct striato-nigral pathway in a rodent model of Parkinson's disease." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ42248.pdf.

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Bai, Jie. "A homogenization based continuum plasticity-damage model for ductile fracture of materials containing heterogeneities." Columbus, Ohio : Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1211910660.

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Li, Tianbai. "Stress integration strategies for a new hardening/softening elasto-plasticity model for structural concrete." Thesis, University of Sheffield, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425181.

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Johansson, Nils. "Estimation of fatigue life by using a cyclic plasticity model and multiaxial notch correction." Thesis, Linköpings universitet, Mekanik och hållfasthetslära, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-158095.

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Mechanical components often possess notches. These notches give rise to stress concentrations, which in turn increases the likelihood that the material will undergo yielding. The finite element method (FEM) can be used to calculate transient stress and strain to be used in fatigue analyses. However, since yielding occurs, an elastic-plastic finite element analysis (FEA) must be performed. If the loading sequence to be analysed with respect to fatigue is long, the elastic-plastic FEA is often not a viable option because of its high computational requirements. In this thesis, a method that estim
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Bai, Jie. "A Homogenization based Continuum Plasticity-Damage Model for Ductile Frature of Materials Containing Heterogeneities." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1211910660.

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Li, Lin. "A Quantized Crystal Plasticity Model for Nanocrystalline Metals: Connecting Atomistic Simulations and Physical Experiments." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1299605340.

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Altaee, Abdul Ameir. "Finite element implementation, validation, and deep foundation application of a bounding-surface plasticity model." Thesis, University of Ottawa (Canada), 1992. http://hdl.handle.net/10393/7882.

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The Bardet model requires nine parameters in order to describe the behavior of a soil. This thesis presents methods of determination of these parameters and the model sensitivity with respect to variation in values of its parameters. This sensitivity analysis illustrates the relative importance of each one of the model parameters in the overall performance of the model. The model parameters are grouped into three categories based on their relative effect on the model performance. The calculation of pore water pressure is achieved by considering an extremely small compressibility for the pore w
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Jackson, Adam. "Cellular and synaptic pathophysiology in a rat model of Fragile X syndrome." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/23600.

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Fragile X syndrome (FXS) is the most commonly inherited form of intellectual disability as well as a leading genetic cause of autism spectrum disorder. It is typically the result of a trinucleotide repeat expansion in the Fmr1 gene which leads to loss of the encoded protein, fragile X mental retardation protein (FMRP). Animal model studies over the past twenty years, mainly focusing on the Fmr1 knockout (KO) mouse, have uncovered several cellular and behavioural phenotypes associated with the loss of FMRP. Seminal work using the Fmr1 KO mouse found that metabotropic glutamate receptor mediated
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Kyakula, Michael. "An improved spread plasticity model for inelastic analysis of R.C. frames subject to seismic loading." Thesis, University of Newcastle Upon Tyne, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399361.

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Peterson, Daniel. "The Effects of Nicotine in the Neonatal Quinpirole Rodent Model of Schizophrenia: Neural Plasticity Mechanisms." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etd/3083.

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The current study was designed to analyze the roles of both α7 and α4β2 nicotinic receptors (nAChRs) in behavioral sensitization and its effects on Brain Derived Neurotrophic Factors (BDNF) and the mammalian target of rapamycin (mTOR) in the neonatal quinpirole model of schizophrenia. Animals were treated neonatally with either quinpirole (1 mg/kg) or saline starting on P1 and treatment persisted through P21. Starting on P33, animals were sensitized to nicotine (0.5 mg/kg free base) every other day up to P49. Following sensitization, brains were harvested at 1 h and 24 h post-drug treatment an
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Toland, Andrew Hamilton. "Short-Term Plasticity at the Schaffer Collateral: A New Model with Implications for Hippocampal Processing." PDXScholar, 2012. https://pdxscholar.library.pdx.edu/open_access_etds/756.

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A new mathematical model of short-term synaptic plasticity (STP) at the Schaffer collateral is introduced. Like other models of STP, the new model relates short-term synaptic plasticity to an interaction between facilitative and depressive dynamic influences. Unlike previous models, the new model successfully simulates facilitative and depressive dynamics within the framework of the synaptic vesicle cycle. The novelty of the model lies in the description of a competitive interaction between calcium-sensitive proteins for binding sites on the vesicle release machinery. By attributing specific m
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Tedjaseputra, Erik Nugroho. "Numerical Simulations of Microstructure-based Crystal Plasticity Finite Element Model for Titanium and Nickel Alloys." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1325084673.

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47

Gurrutxaga, Lerma Beñat. "A dynamic discrete dislocation plasticity model for the study of plastic relaxation under shock loading." Thesis, Imperial College London, 2014. http://hdl.handle.net/10044/1/42360.

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This thesis concerns with Dynamic Discrete Dislocation Plasticity (D3P), a planar method of discrete dis- location dynamics aimed at the study of plastic relaxation processes in crystalline materials subjected to weak shock loading and high strain rates. Traditionally, the study of plasticity under these condi- tions was based on experimental measurement of the macroscopic response of the material. Using these data, well-known macroscopic constitutive laws and equations of state have been formulated. However, direct simulation of dislocations as the dynamic agents of plasticity in those circum
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Salman, Kehlan. "A new elasto-plasticity constitutive model for concrete under multiaxial compression based on experimental observations." Thesis, University of Sheffield, 2007. http://etheses.whiterose.ac.uk/10295/.

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This thesis comprises of two different kinds of work. The first part is focussed on existing experimental data. Investigations and observations of the behaviour of plain concrete under triaxial and multiaxial compression following cyclic loading and a variety of stress paths has been presented. The behaviour of concrete with different constituents was also investigated. The directions of the plastic strain vectors were identified. Two loading surface were also identified: (i) the Peak Nominal Stress surface (PNS) which was identified from the peak stresses recorded from stress control tests an
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Graupner, Michael. "Induction and Maintenance of Synaptic Plasticity." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2008. http://nbn-resolving.de/urn:nbn:de:bsz:14-ds-1221145787153-31869.

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Abstract:
Synaptic long-term modifications following neuronal activation are believed to be at the origin of learning and long-term memory. Recent experiments suggest that these long-term synaptic changes are all-or-none switch-like events between discrete states of a single synapse. The biochemical network involving calcium/calmodulin-dependent protein kinase II (CaMKII) and its regulating protein signaling cascade has been hypothesized to durably maintain the synaptic state in form of a bistable switch. Furthermore, it has been shown experimentally that CaMKII and associated proteins such as protein k
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50

Birget, Philip Laurent Guillaume. "Evolutionary ecology of parasites : life-history traits, phenotypic plasticity, and reproductive strategies." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/28805.

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Abstract:
Adaptive phenotypic plasticity, the ability of a genotype to give rise to different phenotypes in different environments, evolves to allow organisms to fine-tune their life-history traits according to the varying conditions they encounter during their lives. Reproductive investment - the manner in which organisms divide their resources between survival and reproduction - is well studied in evolutionary ecology because it is a key determinant of fitness. However, whilst plasticity in reproductive effort is well understood for free-living multicellular taxa (such as insects, birds, and mammals),
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