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Journal articles on the topic 'Characteristics of klebsiella pneumoniae'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Lee, Ji Yeon, Hyun Ah Kim, and Miri Hyun. "1318. Clinical and Molecular Characteristics of Hypermucoviscous Klebsiella pneumoniae Causing Pneumonia in Korea." Open Forum Infectious Diseases 8, Supplement_1 (2021): S747—S748. http://dx.doi.org/10.1093/ofid/ofab466.1510.

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Abstract Background Invasive Klebsiella pneumoniae (K. pneumoniae) was emerged in Asia, well-known for community-onset liver abscess. Healthcare-associated pneumonia caused by hypervirulent K. pneumoniae has been reported in recent studies. The purpose of this study was to evaluate the clinical and molecular characteristics of hypervirulent K. pneumoniae compared with classic K. pneumoniae in respiratory infection. Methods The study was performed on 163 K. pneumoniae isolates of respiratory infections collected from Keimyung University of Dongsan Medical Center from November 2013 to November 2

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2

Gelbíčová, Tereza, Kristýna Kořená, Lucie Pospíšilová-Hlucháňová, Nicol Straková, and Renáta Karpíšková. "Dissemination and characteristics of Klebsiella spp. at the processed cheese plant." Czech Journal of Food Sciences 39, No. 2 (2021): 113–21. http://dx.doi.org/10.17221/232/2020-cjfs.

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The genus Klebsiella is not generally considered as a major foodborne pathogen and with regard to food production it represents also a hygiene indicator. This study was focused on the monitoring of Klebsiella spp. dissemination at the processed cheese plant and determination of virulence determinants and antibiotic resistance of obtained strains. Klebsiella spp. were detected in 43% (37/87) of samples: swabs from the cheese processing environment (34/69), personnel (2/3) and raw material (milk powder) from an opened packaging (1/7). All tested samples of final processed cheeses were negative f

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3

Jung, Lae-Seung, Ara Jo, Jeongjin Kim, and Juhee Ahn. "Characteristics of Klebsiella pneumoniae exposed to serial antibiotic treatments." Korean Journal of Microbiology 52, no. 4 (2016): 428–36. http://dx.doi.org/10.7845/kjm.2016.6072.

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4

Zheng, Shuwei, Seow Yen Tan, and Helen ML Oh. "Klebsiella Pneumoniae Visceral Organ Abscesses – Clinical Characteristics." Annals of the Academy of Medicine, Singapore 48, no. 2 (2019): 48–54. http://dx.doi.org/10.47102/annals-acadmedsg.v48n2p48.

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Introduction: In recent years, Klebsiella pneumoniae (KP) has emerged as the predominant cause of pyogenic liver abscess in Asia. KP—as the causative microorganism in other visceral organ abscesses—is less described. In this study, we seeked to describe the clinical characteristics of KP visceral organ abscesses in our institution and evaluated the prescription practices of physicians with regard to antibiotic therapy. Materials and Methods: A retrospective analysis of patients with culture positive (blood or abscess aspirate) KP visceral organ abscesses from May 2014 to April 2016 requiring h

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Левченко, К. В., В. М. Мицура, Д. В. Тапальский, Е. В. Карпова, and В. Н. Бондаренко. "Pneumonia Caused by Klebsiella Pneumoniae Combined with COVID-19: Microbiological Characteristics, Clinical Peculiarities and Risk Factors of the Lethal Outcome." Клиническая инфектология и паразитология 13, no. 1 (2024): 99–110. http://dx.doi.org/10.34883/pi.2024.13.1.038.

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Введение. Klebsiella pneumoniae является наиболее распространенным в мире возбудителем инфекций, связанных с оказанием медицинской помощи, роль которых возросла в период пандемии COVID-19. Пациенты, в биоматериалах которых выявлена K. pneumoniae c экстремальной антибиотикорезистентностью (XDR), нуждаются в подборе эффективных комбинаций антибиотиков, определении факторов риска тяжелого течения и неблагоприятного исхода, мониторинге лечения. Цель. Оценить клинико-лабораторные показатели, факторы риска неблагоприятного исхода, чувствительность к антибиотикам и их комбинациям у пациентов с пневмо

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Lu, Linglong, Hainan Xu, Dongping Huang, and Shumei Peng. "Analysis of Clinical Characteristics of Severe Pneumonia in Children Under Regular COVID-19 Outbreak Prevention and Control." Journal of Clinical Medicine Research 3, no. 2 (2022): 72. http://dx.doi.org/10.32629/jcmr.v3i2.857.

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Objective — To investigate the clinical characteristics of severe pneumonia in childhood under the regular prevention and control of the COVID-19 epidemic in 2021. Methods — The clinical data of 132 children with severe pneumonia in our pediatric intensive care unit from January 1, 2021, to December 31, 2021, were counted. Results: There were 132 children diagnosed with severe pneumonia, including 49 with different underlying diseases: 12 with airway dysplasia, 13 with genetic metabolic diseases, 11 with congenital heart disease, 10 with malnutrition, 2 with drowning, and 1 with insecticide po

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Levchenko, K. V., V. М. Mitsura, D. V. Tapalski, E. V. Karpova, and V. N. Bondarenko. "Clinical and microbiological characteristics of viral-bacterial pneumonia caused by Klebsiella pneumoniae in SARS-CoV-2 infected patients." Proceedings of the National Academy of Sciences of Belarus, Medical series 22, no. 1 (2025): 17–25. https://doi.org/10.29235/1814-6023-2025-22-1-17-25.

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The object of study was to investigate the clinical and laboratory characteristics, the outcomes of the disease, the susceptibility to antibiotics and to different combinations in the patients with pneumonia caused by K. pneumoniae associated and not associated with COVID-19.We analysed 93 cases of pneumonia with K. pneumoniae detected in biological materials including 65 ones with COVID-19 and 28 ones without COVID-19.In the both groups, the diseases of the circulatory system and metabolic disorders were the most common concomitant conditions. The laboratory data were not statistically differ

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8

Yan, Kai, Changfu Li, Weiyu Wang, Juan Guo, and Haifeng Wang. "The Molecular Identification and Comprehensive Analysis of Klebsiella pneumoniae Isolated from Industrial Wastewater." Separations 11, no. 4 (2024): 121. http://dx.doi.org/10.3390/separations11040121.

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Industrial wastewater typically contains many organic and inorganic pollutants and is also contaminated by various microorganisms. Microbial species in industrial wastewater have not been extensively investigated. In this experiment, a Klebsiella pneumoniae strain was isolated for the first time from industrial wastewater containing a high concentration of sulfate and phosphate. Mass spectrometry, genetic analysis, and biochemical identification were conducted to understand the genetic and biochemical characteristics of this Klebsiella pneumoniae strain recovered from industrial wastewater. Gr

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9

EGUCHI, Masashi, Yuichi YOKOMIZO, and Chikara KUNIYASU. "Biochemical characteristics of Klebsiella pneumoniae derived from horses." Japanese Journal of Veterinary Science 49, no. 2 (1987): 279–83. http://dx.doi.org/10.1292/jvms1939.49.279.

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10

Vega, Silvio, Fermín Acosta, Iván Landires та ін. "Phenotypic and genotypic characteristics of carbapenemase- and extended spectrum β-lactamase-producing Klebsiella pneumoniae ozaenae clinical isolates within a hospital in Panama City". Therapeutic Advances in Infectious Disease 8 (січень 2021): 204993612110549. http://dx.doi.org/10.1177/20499361211054918.

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Klebsiella pneumoniae spp ozaenae is a versatile bacterial species able to acquire antimicrobial resistance; the species presents a higher antimicrobial resistance profile compared to Klebsiella pneumoniae spp pneumoniae. Carbapenemase and extended spectrum β-lactamase (ESBL)-producing bacteria commonly arise in clinical settings where antimicrobial stewardship is limited. Our study aims to report the phenotypical and genetic characteristics of nosocomial Klebsiella pneumoniae spp ozaenae isolates associated with mortality collected from a tertiary-level hospital in Panama City. In October 202

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11

Ichsanto Permadi, Tri Yudani M.Raras, and Sumarno Reto Prawiro. "Hypervirulent Klebsiella pneumoniae: Characteristic and clinical perspective." World Journal of Advanced Research and Reviews 19, no. 1 (2023): 625–30. http://dx.doi.org/10.30574/wjarr.2023.19.1.1361.

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Background: Hypervirulent K. pneumoniae (hvKP). A virulent pathogen that has the ability to infect individuals in various age, has multiple ports of entry and cause infectious syndromes. Therefore urges an increase awareness and perspective on the characteristics and clinical feature of hvKP, to better understanding and providing appropriate treatment in cases of infection caused by hvKP. Main Text: Hypervirulent K. pneumoniae (hvKP) was first reported in Taiwan in 1986. This bacteria was responsible for liver abscess with septic endophthalmitis, of these cases some of patient have extrahepati

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Ichsanto, Permadi, Yudani M.Raras Tri, and Reto Prawiro Sumarno. "Hypervirulent Klebsiella pneumoniae: Characteristic and clinical perspective." World Journal of Advanced Research and Reviews 19, no. 1 (2023): 625–30. https://doi.org/10.5281/zenodo.10254494.

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<strong>Background:</strong> <i>Hypervirulent K. pneumoniae</i> (hvKP). A virulent pathogen that has the ability to infect individuals in various age, has multiple ports of entry and cause infectious syndromes. Therefore urges an increase awareness and perspective on the characteristics and clinical feature of hvKP, to better understanding and providing appropriate treatment in cases of infection caused by hvKP.<strong>Main Text:</strong> <i>Hypervirulent K. pneumoniae </i>(hvKP) was first reported in Taiwan in 1986.  This bacteria was responsible for liver abscess with septic endophthalm

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13

Егоров, С. К., В. М. Семёнов, and Т. И. Дмитраченко. "Analysis of Klebsiella Pneumoniae Isolates with Extremely High Antibiotic Resistance." Педиатрия. Восточная Европа, no. 3 (November 3, 2022): 325–33. http://dx.doi.org/10.34883/pi.2022.10.3.004.

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Введение. Klebsiella pneumoniae – хорошо известный, традиционно считающийся условно-патогенным микроорганизм. K. pneumoniae способна служить причиной целого ряда тяжелых инфекций у пациентов с ослабленным иммунитетом, страдающих сахарным диабетом, злокачественными новообразованиями, алкогольной зависимостью, а также у лиц, подвергающихся медицинскому вмешательству, как правило, развивающихся в условиях стационара.Цель. Определение генетических характеристик и детерминант антибиотикорезистентности (генов, мутаций, однонуклеотидных полиморфизмов), обуславливающих широкую резистентность к антибио

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14

Esmaeel, Jameela Radi, and Jinan Nadhim Sadeq. "Detection virulence factors of Klebsiella pneumonia from cattle by using PCR tec." Kufa Journal For Veterinary Medical Sciences 8, no. 1 (2017): 231–39. http://dx.doi.org/10.36326/kjvs/2017/v8i14303.

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Identification of K. pneumoniae was avaluated using conventional microbiological characteristics and molecular assays .Milk specimens were collected from cattle suffered from clinical symptoms of mastitis from different farms of AL-Qadisyiah province.Out of 45 samples obtained, 20 isolates ( 44.4 %) were detected as K. pneumonia according to morphology of colonies and biochemical features.Molecular detection of Klebsiella pneumoniae based 16S rRNA gene for determination two virulence factor genes(rmpA,magA) by using specific primer.These genes potent the pathogenesis of Klebisella pneumonia. T

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15

Esmaeel, Jameela Radi, and Jinan Nadhim Sadeq. "Detection virulence factors of Klebsiella pneumonia from cattle by using PCR tec." Kufa Journal For Veterinary Medical Sciences 8, no. 1 (2017): 231–39. http://dx.doi.org/10.36326/kjvs/2017/v8i14303.

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Identification of K. pneumoniae was avaluated using conventional microbiological characteristics and molecular assays .Milk specimens were collected from cattle suffered from clinical symptoms of mastitis from different farms of AL-Qadisyiah province.Out of 45 samples obtained, 20 isolates ( 44.4 %) were detected as K. pneumonia according to morphology of colonies and biochemical features.Molecular detection of Klebsiella pneumoniae based 16S rRNA gene for determination two virulence factor genes(rmpA,magA) by using specific primer.These genes potent the pathogenesis of Klebisella pneumonia. T

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16

Brisse, Sylvain, Virginie Passet, and Patrick A. D. Grimont. "Description of Klebsiella quasipneumoniae sp. nov., isolated from human infections, with two subspecies, Klebsiella quasipneumoniae subsp. quasipneumoniae subsp. nov. and Klebsiella quasipneumoniae subsp. similipneumoniae subsp. nov., and demonstration that Klebsiella singaporensis is a junior heterotypic synonym of Klebsiella variicola." International Journal of Systematic and Evolutionary Microbiology 64, Pt_9 (2014): 3146–52. http://dx.doi.org/10.1099/ijs.0.062737-0.

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Strains previously classified as members of Klebsiella pneumoniae phylogroups KpI, KpII-A, KpII-B and KpIII were characterized by 16S rRNA (rrs) gene sequencing, multilocus sequence analysis based on rpoB, fusA, gapA, gyrA and leuS genes, average nucleotide identity and biochemical characteristics. Phylogenetic analysis demonstrated that KpI and KpIII corresponded to K. pneumoniae and Klebsiella variicola , respectively, whereas KpII-A and KpII-B formed two well-demarcated sequence clusters distinct from other members of the genus Klebsiella . Average nucleotide identity between KpII-A and KpI

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17

Osipova, E. V., and I. V. Shipitsyna. "Informational characteristics of microbial biofilms formed by clinical strains of Klebsiella pneumoniae in vitro on the surface of the cover glass." Genij Ortopedii 24, no. 4 (2018): 478–81. http://dx.doi.org/10.18019/1028-4427-2018-24-4-478-481.

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18

Liu, Yanquan, Hongquan Zhu, Yue Yin, and Zhimin Yan. "Left eye enucleation caused by multi-systemic Klebsiella pneumoniae invasive syndrome." Journal of International Medical Research 50, no. 1 (2022): 030006052110692. http://dx.doi.org/10.1177/03000605211069284.

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Klebsiella pneumoniae is generally considered the most common pathogenic bacterium causing community-acquired pneumonia. In recent years, cases of liver abscess caused by the bacterium and its spread have been reported in Asia and other parts of the world. This clinical symptom of liver abscess caused by hypervirulent K. pneumoniae and its migrating infection is also called invasive K. pneumoniae liver abscess syndrome (IKPLAS). This study explored the clinical characteristics, diagnosis, and treatment of an elderly patient with IKPLAS who experienced multi-organ failure caused by the infectio

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Ito, Ryota, Yuichiro Shindo, Daisuke Kobayashi, et al. "Molecular Epidemiological Characteristics of Klebsiella pneumoniae Associated with Bacteremia among Patients with Pneumonia." Journal of Clinical Microbiology 53, no. 3 (2015): 879–86. http://dx.doi.org/10.1128/jcm.03067-14.

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Some important virulence factors have been elucidated inKlebsiella pneumoniaeinfections. We investigated the relationship between virulence factors and multilocus sequence types (STs) and assessed the risk factors for bacteremia in patients with pneumonia due toK. pneumoniae. From April 2004 through April 2012, a total of 120K. pneumoniaeisolates from patients with pneumonia (23 with bacteremia and 97 without bacteremia) were collected from 10 medical institutions in Japan. Additionally, 10 strains ofK. pneumoniaeserotype K2 that were isolated >30 years ago were included in this study. Thes

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Bagley, Susan T. "Habitat Association of Klebsiella Species." Infection Control 6, no. 2 (1985): 52–58. http://dx.doi.org/10.1017/s0195941700062603.

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AbstractThe genus Klebsiella is seemingly ubiquitous in terms of its habitat associations. Klebsiella is a common opportunistic pathogen for humans and other animals, as well as being resident or transient flora (particularly in the gastrointestinal tract). Other habitats include sewage, drinking water, soils, surface waters, industrial effluents, and vegetation. Until recently, almost all these Klebsiella have been identified as one species, ie, K. pneumoniae. However, phenotypic and genotypic studies have shown that “K. pneumoniae” actually consists of at least four species, all with distinc

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Weber-Dąbrowska, Beata, Maciej Żaczek, Małgorzata Łobocka, et al. "Characteristics of Environmental Klebsiella pneumoniae and Klebsiella oxytoca Bacteriophages and Their Therapeutic Applications." Pharmaceutics 15, no. 2 (2023): 434. http://dx.doi.org/10.3390/pharmaceutics15020434.

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In recent years, multidrug-resistant (MDR) strains of Klebsiella pneumoniae have spread globally, being responsible for the occurrence and severity of nosocomial infections. The NDM-1-kp, VIM-1 carbapenemase-producing isolates as well as extended-spectrum beta lactamase-producing (ESBL) isolates along with Klebsiella oxytoca strains have become emerging pathogens. Due to the growing problem of antibiotic resistance, bacteriophage therapy may be a potential alternative to combat such multidrug-resistant Klebsiella strains. Here, we present the results of a long-term study on the isolation and b

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Ito, Ryota, Yuichiro Shindo, Daisuke Kobayashi, et al. "801Molecular Epidemiological Characteristics of Klebsiella pneumoniae Associated with Bacteremia among Patients with Pneumonia." Open Forum Infectious Diseases 1, suppl_1 (2014): S227. http://dx.doi.org/10.1093/ofid/ofu052.509.

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23

Candan, Esra Deniz, and Nilüfer Aksöz. "Klebsiella pneumoniae: characteristics of carbapenem resistance and virulence factors." Acta Biochimica Polonica 62, no. 4 (2015): 867–74. http://dx.doi.org/10.18388/abp.2015_1148.

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Peirano, Gisele, Dylan R. Pillai, André Pitondo-Silva, David Richardson, and Johann D. D. Pitout. "The characteristics of NDM-producing Klebsiella pneumoniae from Canada." Diagnostic Microbiology and Infectious Disease 71, no. 2 (2011): 106–9. http://dx.doi.org/10.1016/j.diagmicrobio.2011.06.013.

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25

Yang, Y. S., L. K. Siu, K. M. Yeh, et al. "Recurrent Klebsiella pneumoniae Liver Abscess: Clinical and Microbiological Characteristics." Journal of Clinical Microbiology 47, no. 10 (2009): 3336–39. http://dx.doi.org/10.1128/jcm.00918-09.

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26

MOVALIYA, PALAK, KRUNAL D. MEHTA, HIESH SHINGALA, and SWATI JETHAVA. "ANTIMICROBIAL RESISTANCE PATTERN OF KLEBSIELLA PNEUMONIAE STRAINS ISOLATED FROM URINE SAMPLE IN GOVERNMENT HOSPITAL, WESTERN GUJARAT." Asian Journal of Microbiology, Biotechnology & Environmental Sciences 26, no. 04 (2024): 507–12. https://doi.org/10.53550/ajmbes.2024.v26i04.010.

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After respiratory tract infections, urinary tract infections (UTIs) are the second most common infection in the community and healthcare settings, including hospitals. Klebsiella pneumonie causes second most UTIs after Escherichia coli. This pathogen has many virulence characteristics and is producing more resistant strains, including ESBL and Carbapenem-resistant strains. These resistant infections raise morbidity, death, and healthcare expenses. In this work, Klebsiella pneumoniae is isolated from urine samples from a tertiary care hospital and assessed for antimicrobial susceptibility. A te

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WANG, Shuang, Dong LI, Yun-zhuo CHU, Li-ying ZHU, and Feng-zhi LIU. "Determination of oropharyngeal pathogenic colonization in the elderly community." Chinese Medical Journal 122, no. 3 (2009): 315–18. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.2009.03.015.

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Background Pneumonia has become the predominant cause of death for the elderly. It is critical to determine the status of oropharyngeal pathogen colonization in the elderly when treating pneumonia. To explore the efficient approaches to treat age-related pneumonia, we determined the status of oropharyngeal pathogenic colonization in the elderly community. Methods Throat swab cultures were used to isolate oropharyngeal pathogens from 706 residents older than 65 years living in the community of Shenyang City. Characteristics of bacterial strains were sorted and identified using drug sensitivity

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Zemko, V. Yu, and V. K. Okulich. "Influence of microbiological characteristics of infections caused by Klebsiella pneumoniae on antibiotic resistance and severity of the infection process." Сибирский научный медицинский журнал 45, no. 2 (2025): 88–93. https://doi.org/10.18699/ssmj20250209.

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The aim of the study was to investigate influence of microbiological characteristics of infections caused by Klebsiella pneumonia on formation of antibiotic resistance and severity of infectious process.Material and methods. A comparative analysis of biofilm mass, thickness of capsule of K. pneumonia isolated from 26 patients with sepsis and from 8 patients with chronic obstructive pulmonary disease was carried out. The influence of capsule thickness on severity of infectious process and antibiotic resistance was studied.Results and discussion. The mass of K. pneumoniae biofilm isolated from p

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Kim, So Yeon, Ji-Young Rhee, Sang Yop Shin, and Kwan Soo Ko. "Characteristics of community-onset NDM-1-producing Klebsiella pneumoniae isolates." Journal of Medical Microbiology 63, no. 1 (2014): 86–89. http://dx.doi.org/10.1099/jmm.0.067744-0.

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Multilocus sequence typing and in vitro antimicrobial susceptibility testing were performed for three community-onset New Delhi metallo-β-lactamase-1 (NDM-1)-producing Klebsiella pneumoniae isolates from Korea. The genetic structure surrounding the bla NDM-1 gene was determined in bla NDM-1-harbouring plasmids. Three NDM-1-producing K. pneumoniae isolates were found to belong to the same clone (sequence type 340). Each of these isolates showed the same genetic structure surrounding the bla NDM-1 gene. The genes bla NDM-1, ble MBL, trpF and dsbC were flanked by two intact insertion sequences, I

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Kang, Fuqiang, Zili Chai, Beiping Li, et al. "Characterization and Diversity of Klebsiella pneumoniae Prophages." International Journal of Molecular Sciences 24, no. 11 (2023): 9116. http://dx.doi.org/10.3390/ijms24119116.

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Klebsiella pneumoniae is a common human commensal and opportunistic pathogen. In recent years, the clinical isolation and resistance rates of K. pneumoniae have shown a yearly increase, leading to a special interest in mobile genetic elements. Prophages are a representative class of mobile genetic elements that can carry host-friendly genes, transfer horizontally between strains, and coevolve with the host’s genome. In this study, we identified 15,946 prophages from the genomes of 1437 fully assembled K. pneumoniae deposited in the NCBI database, with 9755 prophages on chromosomes and 6191 pro

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Tabriz, Nurlan, Zhanara Nurtazina, Alyona Lavrinenko, Zhumat Mutayhan, and Altynay Taishykova. "Subspecies typing on the example of klebsiella pneumoniae isolated from patients with pulmonary tuberculosis." Polski Merkuriusz Lekarski 53, no. 1 (2025): 67–74. https://doi.org/10.36740/merkur202501109.

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Aim: The purpose of this study was to evaluate sub-species typing by matrix-activated laser desorption/ionisation mass spectrometry on the example of Klebsiella pneumoniae isolated from patients with pulmonary tuberculosis in Karaganda region. Materials and Methods: This study evaluated the potential of MALDI-TOF MS for epidemiological identification of Klebsiella pneumoniae isolated from pulmonary tuberculosis patients in Karaganda region. A total of 47 strains of Klebsiella pneumoniae obtained between 2015 and 2019 were typed. Mass spectra were taken using Microflex LT MALDI-TOF (Bruker) acc

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Sydow, Katharina, Elias Eger, Michael Schwabe, et al. "Geno- and Phenotypic Characteristics of a Klebsiella pneumoniae ST20 Isolate with Unusual Colony Morphology." Microorganisms 10, no. 10 (2022): 2063. http://dx.doi.org/10.3390/microorganisms10102063.

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Klebsiella pneumoniae is a common member of the intestinal flora of vertebrates. In addition to opportunistic representatives, hypervirulent (hvKp) and antibiotic-resistant K. pneumoniae (ABR-Kp) occur. While ABR-Kp isolates often cause difficult-to-treat diseases due to limited therapeutic options, hvKp is a pathotype that can infect healthy individuals often leading to recurrent infection. Here, we investigated the clinical K. pneumoniae isolate PBIO3459 obtained from a blood sample, which showed an unusual colony morphology. By combining whole-genome and RNA sequencing with multiple in vitr

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Bramantono, Bramantono, Brian Eka Rachman, Erika Marfiani, Neneng Dewi Kurniati, Muhammad Vitanata Arifijanto, and Tuksin Jearanaiwitayakul. "The Bacterial Pneumonia Characteristics based on Climate and Meteorological Parameters in Indonesia, the Tropical Country: A Preliminary Study." Biomolecular and Health Science Journal 4, no. 1 (2021): 15. http://dx.doi.org/10.20473/bhsj.v4i1.26926.

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Introduction: As a tropical country, Indonesia has the potential to influence the characteristics of infectious diseases. The purpose of this study was to see how the pattern of pneumonia on various weather components such as rainfall, humidity, and temperature.Methods: This study was carried by retrospective screening in the infectious ward in one of the tertiary referral hospitals.Results: A total of 876 cases of pneumonia from eight treatment rooms were included in the study. The highest pneumonia cases occurred in February with 239 (27.2%) cases followed in April and May with 169 (19.2%) a

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Kryukov, Evgeniy V., Konstantin P. Golovko, Vitaly Yu Markevich, et al. "Characteristics of antibiotic resistance of infectious pathogens in the wounded." Bulletin of the Russian Military Medical Academy 25, no. 2 (2023): 193–202. http://dx.doi.org/10.17816/brmma207771.

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ABSTRACT. This study examines the etiological structure and antibiotic resistance features of pathogens causing infectious complications in wounded patients receiving specialized medical care are considered. A total of 3845 clinical isolates were analyzed from wounded individuals admitted t o a multidisciplinary hospital for treatment. The analysis revealed that polyresistant pathogens, namely, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii were predominant among the isolated microorganisms. The prevalence of Acinetobacter baumannii varied based on the type of clini

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Petrosillo, Taglietti, and Granata. "Treatment Options for Colistin Resistant Klebsiella pneumoniae: Present and Future." Journal of Clinical Medicine 8, no. 7 (2019): 934. http://dx.doi.org/10.3390/jcm8070934.

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Multidrug-resistant (MDR) Klebsiella pneumoniae represents an increasing threat to human health, causing difficult-to-treat infections with a high mortality rate. Since colistin is one of the few treatment options for carbapenem-resistant K. pneumoniae infections, colistin resistance represents a challenge due to the limited range of potentially available effective antimicrobials, including tigecycline, gentamicin, fosfomycin and ceftazidime/avibactam. Moreover, the choice of these antimicrobials depends on their pharmacokinetics/pharmacodynamics properties, the site of infection and the susce

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Goncharov, A. E., D. V. Azarov, A. S. Mokhov, et al. "Characteristics of hypervirulent multi-drug resistant Klebsiella pneumoniae strains in inpatients with severe COVID-19." Infekcionnye bolezni 20, no. 2 (2022): 33–40. http://dx.doi.org/10.20953/1729-9225-2022-2-33-40.

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Severe course of COVID-19 in inpatients can be caused by a number of reasons, including viral and bacterial superinfections. Empirical use of antibiotics, as well as poor infectious control stimulate the emergence and spread of multidrug-resistant bacteria. Klebsiella pneumoniae is the most common carbapenemase-producing bacterial pathogen causing nosocomial infections. These strains became significantly widespread during the COVID-19 pandemic. Objective. To analyze phenotypic and genetic characteristics of K. pneumoniae strains as the dominant bacterial pathogen in severe COVID-19 patients in

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Hwang, Joo-Hee, Jeong-Hwan Hwang, Seung Yeob Lee, and Jaehyeon Lee. "Prostatic Abscess Caused by Klebsiella pneumoniae: A 6-Year Single-Center Study." Journal of Clinical Medicine 11, no. 9 (2022): 2521. http://dx.doi.org/10.3390/jcm11092521.

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Hypervirulent Klebsiella pneumoniae (hvKp) is an important strain that can cause multiple organ infections. Although hvKp infection cases are increasing, there is limited information on the prostatic abscesses caused by K. pneumoniae. Furthermore, the clinical significance of hvKp associated with K1 or K2 capsular types or virulence genes in prostatic abscesses remains unclear. Therefore, we aimed to elucidate the clinical and microbiological characteristics of prostatic abscesses caused by K. pneumoniae in relation to various virulence genes. A retrospective study was performed at a 1200-bed

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Hussein, Khetam, Hanna Sprecher, Tania Mashiach, Ilana Oren, Imad Kassis, and Renato Finkelstein. "Carbapenem Resistance Among Klebsiella pneumoniae Isolates Risk Factors, Molecular Characteristics, and Susceptibility Patterns." Infection Control & Hospital Epidemiology 30, no. 7 (2009): 666–71. http://dx.doi.org/10.1086/598244.

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Background.Carbapenem resistance among isolates of Klebsiella pneumoniae has been unusual.Objectives.To identify risk factors for infection with carbapenem-resistant K. pneumoniae (CRKP) and to characterize microbiological aspects of isolates associated with these infections.Design.Retrospective case-control study.Setting.A 900-bed tertiary care hospital.Results.From January 2006 through April 2007, K. pneumoniae was isolated from 461 inpatients; 88 had CRKP infection (case patients), whereas 373 had carbapenem-susceptible K. pneumoniae infection (control subjects). The independent risk factor

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Lee, Yongwoo, and Young-Mok Song. "Ventriculitis Associated with Liver Abscess Caused by Klebsiella Pneumoniae." Journal of the Korean Neurological Association 38, no. 3 (2020): 210–13. http://dx.doi.org/10.17340/jkna.2020.3.7.

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<i>Klebsiella pneumoniae</i> has been recognized to cause an invasive syndrome characterized by liver abscess and its metastatic infection. The characteristics of metastatic infection involving the central nervous system in this invasive syndrome are poorly understood. The authors report an 84-year-old woman with diabetes mellitus who developed liver abscess caused by <i>K. pneumoniae</i>, complicated with ventriculitis. The patient died despite the antibiotic treatment. Ventriculitis is a rare CNS complication of <i>K. pneumoniae</i> invasive syndrome and r

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Yang, Weijian, Haijun Yao, Caihua Xi, et al. "Prevalence and Clinical Characteristics of Bacterial Pneumonia in Neurosurgical Emergency Center Patients: A Retrospective Study Spanning 13 Years at a Tertiary Center." Microorganisms 11, no. 8 (2023): 1992. http://dx.doi.org/10.3390/microorganisms11081992.

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Patients with brain injuries are at a heightened susceptibility to bacterial pneumonia, and the timely initiation of empiric antibiotic treatment has been shown to substantially reduce mortality rates. Nevertheless, there is a need for knowledge regarding the resistance and prevalence of pulmonary bacterial infections in this patient population. To address this gap, a retrospective study was conducted at a neurosurgical emergency center, focusing on patients with brain injuries. Among the entire patient population, a total of 739 individuals (18.23%) were identified as having bacterial pneumon

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Jung, Jiwon, Ki-Ho Park, Seong Yeon Park, et al. "Comparison of the clinical characteristics and outcomes of Klebsiella pneumoniae and Streptococcus pneumoniae meningitis." Diagnostic Microbiology and Infectious Disease 82, no. 1 (2015): 87–91. http://dx.doi.org/10.1016/j.diagmicrobio.2015.02.006.

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Patilaya, Popi, Dadang Irfan Husori, and Lany Marhafanny. "Susceptibility of Klebsiella Pneumoniae Isolated from Pus Specimens of Post-Surgery Patients in Medan, Indonesia to Selected Antibiotics." Open Access Macedonian Journal of Medical Sciences 7, no. 22 (2019): 3861–64. http://dx.doi.org/10.3889/oamjms.2019.520.

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AIM: This study was to determine the sensitivity of Klebsiella pneumonia isolated from pus specimens of post-surgery patients in Medan, Indonesia to selected antibiotics. METHODS: Samples were collected at the Laboratory of Microbiology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia. The isolated bacteria were identified by Gram’s stain, colony characteristics, and biochemical tests. Susceptibility of K. pneumoniae isolates were tested to selected antibiotics including amikacin, meropenem, levofloxacin, ciprofloxacin, co-trimoxazole, ceftazidime, cefoperazone, cefurox

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Zhao, Jiankang, Chao Liu, Yingmei Liu, et al. "Genomic characteristics of clinically important ST11 Klebsiella pneumoniae strains worldwide." Journal of Global Antimicrobial Resistance 22 (September 2020): 519–26. http://dx.doi.org/10.1016/j.jgar.2020.03.023.

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He, Meirong, Haoyang Li, Zhenxing Zhang, et al. "Microbiological Characteristics and Pathogenesis of Klebsiella pneumoniae Isolated from Hainan Black Goat." Veterinary Sciences 9, no. 9 (2022): 471. http://dx.doi.org/10.3390/vetsci9090471.

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K. pneumoniae is an opportunistic pathogen that leads to widespread infection in humans and animals, seriously threatening human health and animal husbandry development. In our research, we investigated the biological characteristics of the isolate by using a 16S rRNA gene sequencing, biochemical assay, and drug sensitivity test. Moreover, the pathogenicity study, including the bacteria load determination, the histopathology examination, and the RNA sequencing was carried out to explore whether the isolate could cause lung injury in mice through intraperitoneal injection. The results indicated

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Ye, Min, Lei Liu, Bin Liu, Xiangdong Zhou, and Qi Li. "RETRACTED: Ye et al. Drug Resistance and Molecular Characteristics of Carbapenem-Resistant OXA-48-Producing Klebsiella pneumoniae Strains in Hainan, China. Microorganisms 2023, 12, 49." Microorganisms 12, no. 4 (2024): 661. http://dx.doi.org/10.3390/microorganisms12040661.

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Pereira, Rito Santo, Vanessa Cordeiro Dias, Alessandra Barbosa Ferreira-Machado, et al. "Physiological and molecular characteristics of carbapenem resistance in Klebsiella pneumoniae and Enterobacter aerogenes." Journal of Infection in Developing Countries 10, no. 06 (2016): 592–99. http://dx.doi.org/10.3855/jidc.6821.

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Introduction: Bacterial resistance is a growing concern in the nosocomial environment in which Klebsiella pneumoniae and Enterobacter aerogenes play an important role due to their opportunism and carbapenemase-production. This work aimed to evaluate physiological and molecular characteristics of carbapenem-resistant K. pneumoniae and E. aerogenes isolated in a Brazilian tertiary hospital. Methodology: In total, 42 carbapenem-resistant bacteria isolated from clinical specimens were included (21 K. pneumoniae and 21 E. aerogenes). Drug-sensitive K. pneumoniae (n = 27) were also included. Antimic

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Polibin, R. V., E. B. Brusina, O. V. Kovalishena, et al. "Eepidemiological Interregional Multicenter Study of Healthcare-Associated Infections in the Intensive Care Units. First Results." Epidemiology and Vaccinal Prevention 24, no. 1 (2025): 4–9. https://doi.org/10.31631/2073-3046-2025-24-1-4-9.

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The intensive development of medical technologies is accompanied by equally rapid changes in the epidemic process of healthcare-associated infections (HAIs). According to experts, in order to increase the sensitivity of the surveillance system, official registration should be supplemented by multicenter targeted studies.Aim. To determine the prevalence and incidence of HAIs in the intensive care units (ICUs) of the Russian Federation, the dominant pathogens and their antibiotic resistance.Materials and Methods. A one-day epidemiological interregional multicenter cross-section survey of HAIs in

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Sergevnin, V. I., and L. G. Kudryavtseva. "Molecular genetic characteristics of antimicrobial resistance in Klebsiella pneumonia isolates from a cardiac surgical hospital." Medical alphabet, no. 5 (March 24, 2025): 43–47. https://doi.org/10.33667/2078-5631-2025-5-43-47.

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In recent years, there has been a significant increase in the prevalence of multidrug-resistant Klebsiella pneumoniae strains in nosocomial settings.Objectives To investigate the molecular genetic basis of resistance to beta-lactam antibiotics among K. pneumoniae isolates collected from a cardiac hospital in comparison to their phenotypic antibiotic resistance profiles.Methods. A total of 50 clinical K. pneumoniae isolates were obtained from patients with signs of hospital-acquired purulent-septic infections in a cardiac surgery hospital. These isolates were subjected to a bacterial culture an

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Lin, Di, Jian Chen, Yan Yang, Jun Cheng, and Changgui Sun. "Epidemiological study of carbapenem-resistant Klebsiella pneumoniae." Open Medicine 13, no. 1 (2018): 460–66. http://dx.doi.org/10.1515/med-2018-0070.

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AbstractBackgroundThis research is aimed to study the resistance and molecular epidemiological characteristics of carbapenem-resistant Klebsiella pneumoniae (CRKP).Methodology38 isolated CRKP strains were collected from clinical specimens.ResultsThe resistance rates were more than 70.0%. Ampicillin had the highest rates among them (100.0%). 34 strains (89.5%) among the 38 CRKP strains carried blaKPC-2 gene, and 3 strains (7.9%) carried blaIMP-4 gene. 36 strains (94.7%) among the 38 CRKP strains carried blaSHV gene, 29 strains (76.3%) carried blaTEM gene, and 26 strains (68.4%) carried blaCT-M

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Bashir Ismail Olawale, Hauwa Tahir, Sanusi Magaji, and Ayokunu Akinyemi Odewumi. "A Three-Tube Scheme for Same-Day Presumptive Identification of Klebsiella pneumoniae in Clinical Specimens." UMYU Scientifica 1, no. 1 (2022): 36–41. http://dx.doi.org/10.56919/usci.1122.006.

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A three-tube scheme that comprised a urease tube, motility tube and a gluconate-nitrate composite medium tube was evaluated for its reliability in correctly predicting the identity of Klebsiella pneumoniae after six hours of incubation. A total of 33 strains were used to assess the scheme, of which 17 were laboratory stock cultures, 14 were fresh clinical isolates, and two were environmental isolates from soil samples. The three tubes were heavily inoculated to give a density approximating McFarland No. 7 turbidity standard, which is roughly equivalent to a bacterial suspension with a concentr

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