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Journal articles on the topic 'Characterization of Microencapsulating Drug'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Pal, Pawan Chandrashekhar* Mrityunjay Kumar Yasir Akhbar Dar Faizan Jeelani Shergojri Nauneet Kumar Satyam Gulwani. "Preparation And Characterization of Microencapsulating Drug Delivery Systems of Few Anti-Hypertensive Drugs." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 3614–19. https://doi.org/10.5281/zenodo.15480350.

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The present study focuses on the preparation and characterization of microencapsulated drug delivery systems for selected antihypertensive agents. Microencapsulation is an advanced drug delivery approach that enhances the pharmacokinetic profile, stability, and controlled release of therapeutic agents. In this project, various antihypertensive drugs—such as amlodipine, atenolol, and enalapril cellulose and sodium alginate via techniques such as solvent evaporation and ionic gelation. The goal of developing microencapsulating drug delivery systems (DDS) for antihypertensive treatments is

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Loca, Dagnija, Osvalds Pugovics, Liga Berzina-Cimdina, and Janis Locs. "Preparation and Characterization of Highly Water Soluble Drug Loaded PLA Microcapsules." Advances in Science and Technology 57 (September 2008): 176–81. http://dx.doi.org/10.4028/www.scientific.net/ast.57.176.

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Microencapsulation of highly water soluble pharmaceutical substances (solubility more than 1g/ml), especially if high drug loading is required (more than 50%) is a big challenge. Biodegradable polylactide as coating material and polyvinyl alcohol as surfactant were found suitable for this purpose. Active substance was microencapsulated using slightly modified waterin- oil-in-water technique which involves dissolving of the drug in the water and polymer in methylene chloride and forming an emulsion in water using a surfactant. Procedure of microencapsulation was followed by filtration and dryin

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3

Faizan Asad, Faiza Fiaz, Amna Sheraz, Ayesha Nabi Ahmed, Irfan Javaid, and Talib Hussain. "Characterization and stability analysis of metformin HCl microcapsules formulated by complex coacervation technique." Journal of Contemporary Pharmacy 7, no. 1 (2023): 1–7. http://dx.doi.org/10.56770/jcp2023711.

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Objective: Metformin hydrochloride possesses a shorter sort of biological half-life of 1.5–1.6 h with having the absolute type of bioavailability that ranges between 50-60%, the moment it is administered orally. Reduced GIT disturbances and low bioavailability can be optimized by developing microencapsulation of metformin that could prove beneficial. Method: Paraffin oil had been used in obtaining specific types of primary emulsions, whereas the material that was used in the coating of microencapsulation had been identified as sodium alginate. In the process of complex coacervation, a substanc

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Asad, Faizan, Faiza Fiaz, Amna Sheraz, Ayesha Nabi Ahmed, Irfan Javaid, and Talib Hussain. "Characterization and stability analysis of metformin HCl microcapsules formulated by complex coacervation technique." Journal of Contemporary Pharmacy 7, no. 1 (2023): 1–7. http://dx.doi.org/10.56770/jcp.2023711.

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Objective: Metformin hydrochloride possesses a shorter sort of biological half-life of 1.5–1.6 h with having the absolute type of bioavailability that ranges between 50-60%, the moment it is administered orally. Reduced GIT disturbances and low bioavailability can be optimized by developing microencapsulation of metformin that could prove beneficial. Method: Paraffin oil had been used in obtaining specific types of primary emulsions, whereas the material that was used in the coating of microencapsulation had been identified as sodium alginate. In the process of complex coacervation, a substanc

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Đekić, Ljiljana, and Ana Ćirić. "Modeling of in vitro drug release from polymeric microparticle carriers." Arhiv za farmaciju 72, no. 6 (2022): 591–620. http://dx.doi.org/10.5937/arhfarm72-40229.

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Incorporation of active substances in polymeric microparticles (microencapsulation) is an important technological strategy used in the pharmaceutical industry to improve the functionality, quality, safety and/or therapeutic efficiency of pharmaceutical preparations for different routes of administration. The current focus of research in this field is on the encapsulation of small molecules and macromolecules into microparticles based on biocompatible synthetic polymers and biopolymers, such as polypeptides and polysaccharides, in order to achieve preferable drug release kinetics and many other

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Bano, Farheen, Mohd Kalim, and Pooja Yadav. "Formulations, Characterization and Evaluation of Clarithromycin loaded Mucoadhesive Microspheres for Peptic Ulcers." Journal of Neonatal Surgery 14, no. 12S (2025): 800–813. https://doi.org/10.52783/jns.v14.3373.

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Mucoadhesive formulations orally would achieve a substantial increase in the length of stay of the drug in GI tract. Mucoadhesive microsphere carrier systems are made from the biodegradable polymers in sustained drug delivery. Among all the fabricated formulations, F9 was optimized as final formulation showing first order release kinetics and extended drug release profile over a period of 10h (73.1%) and fitted to our desired target, with acceptable microencapsulation efficiency (78 %) and mucoadhesive property (76%). having good flow properties, and smaller particle size (204±09). the formula

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Sharma, Tanvi, Harpreet Kaur, Amandeep Kaur, et al. "Synthesis of Iron Based Biocompatible Metal Organic Frameworks for Microencapsulation of Docetaxel." Nano Hybrids and Composites 12 (November 2016): 74–78. http://dx.doi.org/10.4028/www.scientific.net/nhc.12.74.

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Tunable properties of porous metal organic frameworks (MOFs) make them a potential candidate for sustained release of functionally active biomolecules. Current study describes in situ encapsulation of anti-cancer drug, docetaxel in iron based MOFs for drug delivery applications. MOFs were synthesized using emulsification approach by mixing FeCl3.4H2Oand benzene tricarboxylate (BTC) in 1:1 molar ratio in the presence of cetyl trimethyl ammonium bromide (CTAB). Optical characterization of the NMOFs was done using UV-visible and FTIR spectroscopy. The peak obtained at 265 nm in the UV-visible spe

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Chinmaya Mahapatra, Padala Narasimha Murthy, Sudhir Kumar Sahoo, Anjan Kumar Mahapatra, and Prasanna Kumar Dixit. "Preparation iiand characterization of mucoadhesive microcapsules of paclitaxel." International Journal of Research in Pharmaceutical Sciences 11, no. 2 (2020): 2575–83. http://dx.doi.org/10.26452/ijrps.v11i2.2262.

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The objective of the present work was to develop paclitaxel encapsulated mucoadhesive microcapsules with an aim to enhance its efficacy and control the drug release in cancer patients. Paclitaxel microcapsules with a coat consisting of sodium alginate and mucoadhesive polymer such as acacia, Carbomer 941, Povidone K-30, Macrogol (PEG 6000) were prepared by ionotropic gelation technique and were evaluated for morphological characters, drug content, loading efficiency, drug–polymer interactions, swelling ratio, mucoadhesive properties and in vitro drug release. The resulting microcapsules were d

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Muhaimin, Muhaimin, Yusnaidar Yusnaidar, Wilda Syahri, Madyawati Latief, and Anis Yohana Chaerunisaa. "Microencapsulation of Macaranga gigantea Leaf Extracts: Production and Characterization." Pharmacognosy Journal 12, no. 4 (2020): 716–24. http://dx.doi.org/10.5530/pj.2020.12.104.

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Nanjwade, Basavaraj K. "Development of Nanocolloidosome Based Formulations and Characterization." Nanomedicine & Nanotechnology Open Access 8, no. 4 (2023): 1–19. http://dx.doi.org/10.23880/nnoa-16000268.

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Microencapsulation, 30 year old field is still growing with development of new materials and active ingredient. Encapsulation is an imperative technology used to deliver the component to targeted site in an intact manner with no effect from surrounding environment. Colloidosome a novel class of microcapsule generated from the concept Pickering emulsion which is used for production of microcapsule by fixing the particle assembly at interface. Colloidosomes are hollow spherical capsule developed from controlled self-assembly of colloidal particles on emulsion droplets which reduces total interfa

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M, Hariyadi D., Hendradi E, and Sharon N. "Development of Carrageenan Polymer for Encapsulation of Ciprofloxacin HCL: In Vitro Characterization." International Journal of Drug Delivery Technology 9, no. 01 (2019): 89–93. http://dx.doi.org/10.25258/ijddt.9.1.14.

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This study reported the properties of microspheres based Carrageenan polymers with Ciprofloxacin HCl antibiotic as a model for dry powder inhalation (DPI). Microspheres Ciprofloxacin-Carrageenan was prepared through ionic gelation process which is a widely used microencapsulation technique in the pharmaceutical industry. Microspheres formula consists of formula using 0.5 and 1% carragenan polymer and 0.2 and 0.6% KCl crosslinker which was named as F1, F2, F3 and F4. Microspheres were characterized for their yield, morphology, entrapment efficiency, drug loading and particle size. Results revea

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Dr., Archana D. Kajale, Shilpa R. Gawande Dr., Madhuri A. Channawar Dr., Raut Kalyani Junghari Pratiksha, and satpute Snehal. "Design, Characterization and Evaluation of Floating Microencapsules of Ilaprazole by Hot Melt Granulation Method." Pharmaceutical and Chemical Journal 9, no. 3 (2022): 150–59. https://doi.org/10.5281/zenodo.13972712.

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Microencapsulation is described as a process of enclosing micron-sized particles of solids or droplets of liquids or gasses in an inert shell, which in turn isolates and protects them from the external environment. Hot-melt granulation (HMG) has gained interest in the pharmaceutical field as a processing technology capable of producing solid dispersions with a high degree of drug-polymer interactions. The simultaneous mechanical and thermal shear of samples achieved by HMG can noticeably modify drug properties such as solubility, poor taste, and flow-ability, while producing sustained drug del

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Kifayat, Ullah Shah, Majid Khan Gul, and Dilawar Naz. "DILTIAZEM HCL MICROCAPSULES USING ETHYL CELLULOSE ETHER DERIVATIVE POLYMER AS RELEASE RETARDING AGENT: IN-VITRO CHAPTER." International Journal of Research - GRANTHAALAYAH 3, no. 8 (2017): 78–93. https://doi.org/10.5281/zenodo.847146.

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This study presents sustained releasemicroencapsulation of Diltiazem HCL. Its in-vitro dissolution study in phosphate buffer pH 7.4 as dissolution medium and in vivo behaviour in animal subjects. The microcapsules were prepared using polymers Ethocel 7P and Ethocel 7FP at two different drug to polymer (D: P) ratios i.e. 1:5 and 1:10 and the effect of concentration was observed on drug release behaviour. The prepared microcapsules were evaluated for different physical characteristics i.e. Bulk density, Tap density, Compressibility index, Hausner’s ratio and Angle of repose. Characterization of

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14

Madiyar, Foram, Liam Suskavcevic, Kaitlyn Daugherty, et al. "Optimizing Production, Characterization, and In Vitro Behavior of Silymarin–Eudragit Electrosprayed Fiber for Anti-Inflammatory Effects: A Chemical Study." Bioengineering 11, no. 9 (2024): 864. http://dx.doi.org/10.3390/bioengineering11090864.

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Inflammatory Bowel Disease (IBD) is a chronic condition that affects approximately 1.6 million Americans. While current polyphenols for treating IBD can be expensive and cause unwanted side effects, there is an opportunity regarding a new drug/polymer formulation using silymarin and an electrospray procedure. Silymarin is a naturally occurring polyphenolic flavonoid antioxidant that has shown promising results as a pharmacological agent due to its antioxidant and hepatoprotective characteristics. This study aims to produce a drug–polymer complex named the SILS100-Electrofiber complex, using an

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Safitri, Anna, and Nadiyah Zuhroh. "Microencapsulation Combination of Nigella sativa and Cosmos caudatus Kunth and In Vitro Protein Denaturation Inhibition Assay." JSMARTech 3, no. 1 (2022): 029–34. http://dx.doi.org/10.21776/ub.jsmartech.2022.003.01.29.

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Microencapsulation is a method of coating the active ingredients to form microparticles that can be used as a drug delivery agent. This study aims to determine the effect of sodium tripolyphosphate (Na-TPP) concentration and the stirring time in microencapsulation process of extract combination of N. sativa and C. caudatus K., as well as the ability to inhibit protein denaturation. Microencapsulation was carried out with various concentrations (w/v) of Na-TPP 0.2%; 0.4% and 0.6% and stirring time of 60, 90, and 120 min. The optimum conditions of microencapsulation were obtained at 0.2% Na-TPP

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Cárdenas-Triviño, Galo, Sebastián Monsalve-Rozas, and Luis Vergara-González. "Microencapsulation of Erlotinib and Nanomagnetite Supported in Chitosan as Potential Oncologic Carrier." Polymers 13, no. 8 (2021): 1244. http://dx.doi.org/10.3390/polym13081244.

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Microcapsules (MC) based on chitosan (CH) and including nano-magnetite and erlotinib were synthesized. The microparticles were characterized by SEM, FT-IR and TGA. The percentage of encapsulation was determined, as well as its microbiological activity. Finally, the effectiveness of the formulation was evaluated in terms of cell viability and/or toxicity when compared with the reference drug. The formulation used to prepare the microcapsules showed some bacteriostatic properties. The characterization of microcapsules exhibited amorphous spherical shape and average size of 1.29, 1.58 and 1.62 mm

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Faried, Ahmad, Achmad Adam, Wahyu Widowati, et al. "Characterization of Microencapsulation Human Adipose Tissue Mesenchymal Stem Cells (hAT-MSCs) and Nanoparticle of Conditioned Medium of AT-MSCs." Trends in Sciences 20, no. 6 (2023): 6425. http://dx.doi.org/10.48048/tis.2023.6425.

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This study aims to characterize the microencapsulated type of human Adipose Tissue Mesenchymal Stem Cells (hAT-MSCs) and nanoparticles containing a conditioned medium of hAT-MSCs (CM-hATMSCs). The hAT-MSCs microencapsulation was measured the cells viability on 1st, 7th, and 14th days, by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethylphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay, stability test was performed using magnetic stirrer at a speed of 300, 700, 1100, and 1200 rpm (revolutions per minutes) and applied on hAT-MSCs microencapsulation. The particle size of CM-hATMSCs nanoparticles

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Wati, Galuh Putri Erika, Rahmi Hayatunnufus, and Emil Budianto. "Characterization and Efficiency Test of Nifedipine (NIF) Microencapsulation Using Polyblend of Poly(Lactic Acid) and Poly(Ɛ-Caprolactone)." Materials Science Forum 947 (March 2019): 26–31. http://dx.doi.org/10.4028/www.scientific.net/msf.947.26.

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Hypertension, which often dubbed as “silent killer”, is a global health problem due to high prevalence worldwide and led to several diseases such as coronary heart attack and stroke. To treat this disease, nifedipine (NIF) is usually being consumed to reduce the high blood pressure into normal. However, the repetitive dosage of this drug may cause a side effect that can lower the effectiveness of this treatment. Thus, the controlled drug delivery system is utilized to increase the effectivity of NIF with the optimal daily dose. In this research, the polyblend of poly (lactic acid) (PLA) and po

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Rana Riyadh Al-ani and H. N. K. AL-Saman. "Formulation, Development and Characterization of Microspheres of Calcium Channel Blocker." Journal of Pharmaceutical Negative Results 13, no. 4 (2022): 820–25. http://dx.doi.org/10.47750/pnr.2022.13.04.110.

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"AIM"- Using a new drug delivery technology, such as Nifedipine microspheres, this study sought to increase the solubility of a particular calcium channel blocker."MATERIAL & METHODS"- Quasi-emulsion diffusion is used to create floating microspheres of Nifedipine. A magnetic stirrer at 50 rpm is used at room temperature to dissolve the predetermined weighted amount of Nifedipine, ethylcellulose, "polyethylene oxide, and hydroxy propylmethyl cellulose (HPMC K15M)". Particle size, bulk density, compressibility index, and attitude of repose are used to describe the microsphere's "values benef

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Zhang, Wen, Yan Gao, Ning Yang, et al. "Sinomenine-loaded microcapsules fabricated by phase reversion emulsification-drying in liquid method: An evaluation of process parameters, characterization, and released properties." Journal of Bioactive and Compatible Polymers 33, no. 4 (2017): 382–96. http://dx.doi.org/10.1177/0883911517751159.

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Sinomenine is a natural alkaloid with important biological activities (e.g. anti-cancer, anti-inflammatory, and anti-allergic). However, the unstability and short half-life absolutely limited its application to foods. Microencapsulation technology can offer a way to solve these issues. In this study, polylactic acid microcapsules loading sinomenine hydrochloride were fabricated by phase inversion emulsification-drying in liquid technique. The results showed that microcapsules had nice spherical shape, uniform particle size, and free flowing. The encapsulation efficiency was 89.2% and drug load

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Lestari, Sri Rahayu, Abdul Ghofur, Siti Imroatul Maslikah, et al. "Profiling of Single Garlic Extract Microencapsulation: Characterization, Antioxidant Activity, and Release Kinetic." Journal of Tropical Biodiversity and Biotechnology 8, no. 3 (2023): 79072. http://dx.doi.org/10.22146/jtbb.79072.

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Single garlic is known to have many benefits as an alternative therapy for various types of metabolic syndrome. The bioactive compounds, allicin and alliin, in garlic are unstable and easily degraded in digestion. Chitosan-alginate microencapsulation is thought to increase stability and protect active compound so its therapeutic effect is more optimal. This study aimed to characterize the microencapsulation chitosan-alginate of single garlic extract (MCA- SGE), as well as to examine the antioxidant activity and kinetic release of MCA-SGE in vitro. The research procedure includes the steps of s

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Nnamani, Petra O., Adaeze C. Echezona, Obialunamma C. Metu, et al. "Formulation and characterization of artemether-loaded sodium alginate microcapsules." Tropical Journal of Pharmaceutical Research 19, no. 7 (2020): 1341–49. http://dx.doi.org/10.4314/tjpr.v19i7.1.

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Purpose: To increase the solubility of artemether (ART) in Transcutol® HP through microencapsulation in sodium alginate polymer to achieve sustained in vivo release.Method: Graded concentrations of ART (0.00, 0.25, 0.50, 0.75, and 1.00 g) microcapsules were produced using Tween® 80 by the cold homogenization method at 24 x 1000 rpm for 15 min. Characterization based on yield, encapsulation efficiency (EE), particle size, pH stability, differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR) and in vivo release using Peter’s four-day suppressive protocol in Wistar

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Sarabia-Vallejo, Álvaro, María del Mar Caja, Ana I. Olives, M. Antonia Martín, and J. Carlos Menéndez. "Cyclodextrin Inclusion Complexes for Improved Drug Bioavailability and Activity: Synthetic and Analytical Aspects." Pharmaceutics 15, no. 9 (2023): 2345. http://dx.doi.org/10.3390/pharmaceutics15092345.

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Many active pharmaceutical ingredients show low oral bioavailability due to factors such as poor solubility and physical and chemical instability. The formation of inclusion complexes with cyclodextrins, as well as cyclodextrin-based polymers, nanosponges, and nanofibers, is a valuable tool to improve the oral bioavailability of many drugs. The microencapsulation process modifies key properties of the included drugs including volatility, dissolution rate, bioavailability, and bioactivity. In this context, we present relevant examples of the stabilization of labile drugs through the encapsulati

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Gunawan, Firza Rajasa, Siti Mariyah Ulfa, and Anna Safitri. "Freeze-Drying Microencapsulation of <i>Ruellia tuberosa</i> L. Extracts: A Comparative Study Using Different Polymers as Encapsulants." Indonesian Journal of Chemistry 25, no. 1 (2025): 37. https://doi.org/10.22146/ijc.95246.

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Ruellia tuberosa L. leaf and root extracts have been investigated for their biological activity and potential health advantages, including their antidiabetic, antioxidant, and antidiuretic qualities. This research evaluates the freeze-drying microencapsulation of R. tuberosa L. extracts using gum Arabic, maltodextrin, and their combination as coating materials. The resulting microcapsules were tested for encapsulation efficiency, biological activity, and controlled release. Characterization techniques included scanning electron microscopy (SEM), Fourier-transform infrared (FTIR) spectroscopy,

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Rahma, Amalia Nur, Dahniar Nur Aisyah, Yuslinda Annisa, Abdul Gofur, Siti Imroatul Maslikah, and Sri Rahayu Lestari. "Characterization and Hemocompatibility Assay of Microencapsulation Chitosan-Alginate Single Garlic Extract-loaded (MCA-SGE)." BIO Web of Conferences 117 (2024): 01011. http://dx.doi.org/10.1051/bioconf/202411701011.

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Single garlic is a tropical plant with high bioactive compounds. Most bioactive compound found in single garlic is allicin but it has low bioavailability. Allicin was classified to reactive sulfur species (RSS) and has the ability to damage eukaryotic cells, for example is red blood cells (RBC). The damaged of RBC was minimized with a specific mechanism using the drug delivery system (DDS) with Microencapsulation Chitosan- Alginate (MCA). The aim of this study is to characterize and test the hemocompatibility of RBC. Single garlic extraction method using maceration with 70% ethanol. Optimal fo

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Ain, Noor Ul, Shuye Wu, Xiang Li, Duxin Li, and Zhenqing Zhang. "Isolation, Characterization, Pharmacology and Biopolymer Applications of Licorice Polysaccharides: Review." Materials 15, no. 10 (2022): 3654. http://dx.doi.org/10.3390/ma15103654.

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Licorice is known as “Gan-Cao” in traditional Chinese Medicine (TCM), belonging to the genus Glycyrrhiza (Family: Fabaceae/Leguminosae). It has a long medicinal history and wide applications in China. Polysaccharides of licorice (LPs) are one of the key bioactive components. As herbal polysaccharides attracted increasing interest in the past several decades, their extraction, isolation, structural characterization, pharmacological activities, and medicinal application have been explored extensively. It is worth heeding that the method of extraction and purification effects LPs, apart from spec

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Mendes, Jessica Bitencourt Emilio, Manoela Klüppel Riekes, Viviane Matoso de Oliveira, et al. "PHBV/PCL Microparticles for Controlled Release of Resveratrol: Physicochemical Characterization, Antioxidant Potential, and Effect on Hemolysis of Human Erythrocytes." Scientific World Journal 2012 (2012): 1–13. http://dx.doi.org/10.1100/2012/542937.

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Microparticles of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and poly(ε-caprolactone) (PCL) containing resveratrol were successfully prepared by simple emulsion/solvent evaporation. All formulations showed suitable encapsulation efficiency values higher than 80%. PHBV microparticles revealed spherical shape with rough surface and presence of pores. PCL microparticles were spherically shaped with smooth surface. Fourier-transformed infrared spectra demonstrated no chemical bond between resveratrol and polymers. X-ray powder diffraction patterns and differential scanning calorimetry ana

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Zahara, Izaz Aqeiluz, Sutrisno Sutrisno, Siti Mariyah Ulfa, and Anna Safitri. "Microencapsulation by Spray drying of Cosmos caudatus Kunth. Extracts Using Gum Arabic: Influencing Factors and Controlled Release." Indonesian Food Science and Technology Journal 8, no. 1 (2024): 27–35. https://doi.org/10.22437/ifstj.v8i1.32818.

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Advanced drug delivery systems are required due to the increasing advancement in science and technology, with a common example being microencapsulation. This system is affected by the manufacturing conditions and slow release of bioactive compounds inside microcapsule. In general, phytochemicals in the edible plant, Cosmos caudatus Kunth, specifically flavonoids, offer several health benefits but are susceptible to degradation which reduces biological activities. Therefore, this study aimed to encapsulate extract using spray drying method, which can be used as wall material in Gum Arabic. Micr

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Valdes, Oscar, Daniel Bustos, Luis Guzmán, et al. "The Controlled Release of Abscisic Acid (ABA) Utilizing Alginate–Chitosan Gel Blends: A Synergistic Approach for an Enhanced Small-Molecule Delivery Controller." Gels 10, no. 3 (2024): 185. http://dx.doi.org/10.3390/gels10030185.

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The integration of abscisic acid (ABA) into a chitosan–alginate gel blend unveils crucial insights into the formation and stability of these two substances. ABA, a key phytohormone in plant growth and stress responses, is strategically targeted for controlled release within these complexes. This study investigates the design and characterization of this novel controlled-release system, showcasing the potential of alginate–chitosan gel blends in ABA delivery. Computational methods, including molecular dynamics simulations, are employed to analyze the structural effects of microencapsulation, of

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Razavi, Seyedehhamideh, Sajjad Janfaza, Nishat Tasnim, Deanna L. Gibson, and Mina Hoorfar. "Microencapsulating polymers for probiotics delivery systems: Preparation, characterization, and applications." Food Hydrocolloids 120 (November 2021): 106882. http://dx.doi.org/10.1016/j.foodhyd.2021.106882.

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Kerbab, Khawla, Francesca Sansone, Lahcene Zaiter, et al. "Halimium halimifolium: From the Chemical and Functional Characterization to a Nutraceutical Ingredient Design." Planta Medica 85, no. 11/12 (2019): 1024–33. http://dx.doi.org/10.1055/a-0953-6007.

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Abstract Halimium halimifolium (Hh) is a shrub used in Algerian folk medicine to treat gastrointestinal pain. An UHPLC-PDA-ESI/MSn method was developed to identify the metabolic profile of the traditionally used infusion (Hh-A) from the aerial parts. The structures of flavanols were confirmed by NMR analysis after the isolation procedure from a hydrohalcolic extract (Hh-B) that also allowed for the identification of phenolic acids, an aryl butanol glucoside, and different derivatives of quercetin, myricetin, and kaempferol. Tiliroside isomers were the chemical markers of Hh-A and Hh-B (54.33 a

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Chowdary, KPR, P. Mohapatra, and MN Murali Krishna. "Evaluation of olibanum resin as microencapsulating agent for controlled drug delivery." Indian Journal of Pharmaceutical Sciences 68, no. 4 (2006): 461. http://dx.doi.org/10.4103/0250-474x.27818.

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Rajapaksha, Surakshi Wimangika, and Naoto Shimizu. "Development and Characterization of Functional Starch-Based Films Incorporating Free or Microencapsulated Spent Black Tea Extract." Molecules 26, no. 13 (2021): 3898. http://dx.doi.org/10.3390/molecules26133898.

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Antioxidant polyphenols in black tea residue are an underused source of bioactive compounds. Microencapsulation can turn them into a valuable functional ingredient for different food applications. This study investigated the potential of using spent black tea extract (SBT) as an active ingredient in food packaging. Free or microencapsulated forms of SBT, using a pectin–sodium caseinate mixture as a wall material, were incorporated in a cassava starch matrix and films developed by casting. The effect of incorporating SBT at different polyphenol contents (0.17% and 0.34%) on the structural, phys

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Leyva-Porras, César, María Zenaida Saavedra-Leos, Laura Araceli López-Martinez, et al. "Strawberry Juice Powders: Effect of Spray-Drying Conditions on the Microencapsulation of Bioactive Components and Physicochemical Properties." Molecules 26, no. 18 (2021): 5466. http://dx.doi.org/10.3390/molecules26185466.

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The drying of fruit juices has advantages such as easy handling of powders, reduction in volume, and preservation of the characteristics of the fruit. Thus, in this work, the effect of the spray drying conditions of strawberry juice (SJ) with maltodextrin (MX) as a carrying agent on the microencapsulation of bioactive compounds and physicochemical properties was studied. The content of phenolic compounds and antioxidant activity showed higher values at low concentrations of MX, while the effect of drying temperature was negligible. The thermal characterization showed that the low molecular wei

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Zhang, Qionglian, Yan Chen, Fang Geng, and Xiaoyun Shen. "Characterization of Spray-Dried Microcapsules of Paprika Oleoresin Induced by Ultrasound and High-Pressure Homogenization: Physicochemical Properties and Storage Stability." Molecules 28, no. 20 (2023): 7075. http://dx.doi.org/10.3390/molecules28207075.

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As an indispensable process in the microencapsulation of active substances, emulsion preparation has a significant impact on microencapsulated products. In this study, five primary emulsions of paprika oleoresin (PO, the natural colourant extracted from the fruit peel of Capsicum annuum L.) with different particle sizes (255–901.7 nm) were prepared using three industrialized pulverization-inducing techniques (stirring, ultrasound induction, and high-pressure homogenization). Subsequently, the PO emulsion was microencapsulated via spray drying. The effects of the different induction methods on

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Li, Mengjie, Puyu Chen, Yichen Lin, Song Miao, and Hairong Bao. "Preparation and Characterization of a Hypoglycemic Complex of Gallic Acid–Antarctic Krill Polypeptide Based on Polylactic Acid–Hydroxyacetic Acid (PLGA) and High-Pressure Microjet Microencapsulation." Foods 13, no. 8 (2024): 1177. http://dx.doi.org/10.3390/foods13081177.

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Gallic acid–Antarctic krill peptides (GA-AKP) nanocapsules (GA-AKP-Ns) were prepared using a dual delivery system with complex emulsion as the technical method, a high-pressure microjet as the technical means, polylactic acid–hydroxyacetic acid (PLGA) as the drug delivery vehicle, and GA-AKP as the raw material for delivery. This study aimed to investigate the effects of microjet treatment and the concentration of PLGA on the physicochemical properties and stability of the emulsion. Under optimal conditions, the physicochemical properties and hypoglycemic function of nano-microcapsules prepare

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Mawn, M. P., and R. W. Linton. "Cross-Sectional Imaging of Coated Drug Granules." Proceedings, annual meeting, Electron Microscopy Society of America 48, no. 2 (1990): 346–47. http://dx.doi.org/10.1017/s0424820100135332.

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Coatings on pharmaceutical products serve many purposes such as hiding an unpalatable drug taste, giving increased stability, and providing controlled-release dosage. The analysis of coatings on drug granules has been performed through “bulk” studies, such as dissolution tests, stability tests, and sieve analysis, which provide little direct structural information about the coating. Microstructural information such as coating thickness, uniformity, and porosity is necessary to help optimize processing conditions as well as to predict dissolution behavior and resultant biological activity. A sa

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Baranauskaite, Juste, Mehmet Ali Ockun, Burcu Uner, Cetin Tas, and Liudas Ivanauskas. "Effect of the Amount of Polysorbate 80 and Oregano Essential Oil on the Emulsion Stability and Characterization Properties of Sodium Alginate Microcapsules." Molecules 26, no. 20 (2021): 6304. http://dx.doi.org/10.3390/molecules26206304.

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Essential oils have a high volatility that leads to evaporation and loss of their pharmacological effect when exposed to the environment. The objectives of the present work were to prepare microcapsules with oregano essential oil by extrusion using sodium alginate as a shell material and non-ionic surfactant polysorbate 80 as an emulsifier to stabilize the emulsion. The present study was aimed to evaluate the physical parameters of microcapsules and to compare the influence of the amount of emulsifier and the essential oil-to-emulsifier ratio on the capsules’ physical parameters and encapsulat

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Petrulyte, Salvinija, Deimante Vankeviciute, and Donatas Petrulis. "Characterization of structure and air permeability of aromatherapic terry textile." International Journal of Clothing Science and Technology 28, no. 1 (2016): 2–17. http://dx.doi.org/10.1108/ijcst-01-2015-0013.

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Purpose – The purpose of this paper is to investigate the physical properties of smart aromatherapic ramie/cotton terry fabrics containing microcapsules (MC) with essential Eucalyptus oil. Design/methodology/approach – Terry fabrics are manufactured by changing the weft density. The air permeability is determined for grey and microencapsulated textile. The factorial designs are made. For informative experiment the linear type of regression is analysed. Development of physical properties of microencapsulated terry fabrics is discussed. Findings – The air permeability of aromatherapic terry fabr

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Pathak, Y. V., and A. K. Dorle. "Evaluation of Propylene Glycol Rosin Ester as Microencapsulating Material and Study of Dissolution Kinetics." Drug Development and Industrial Pharmacy 14, no. 15-17 (1988): 2557–65. http://dx.doi.org/10.3109/03639048809152032.

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Morkhade, Dinesh M. "Evaluation of gum mastic (Pistacia lentiscus) as a microencapsulating and matrix forming material for sustained drug release." Asian Journal of Pharmaceutical Sciences 12, no. 5 (2017): 424–32. http://dx.doi.org/10.1016/j.ajps.2017.05.002.

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E Silva, Thâmara Machado, Osvaldo Gomes Pinto, Lucas Leonardo Da Silva, Raissa Kelly Correa De Paiva, Leonardo Luiz Borges, and Samantha Salomão Caramori. "Gum of Terminalia argentea Mart. Et. Zucc. (Combretaceae) as a Resource in Biotechnology Processes: Chemistry and Toxicity." Fronteiras: Journal of Social, Technological and Environmental Science 8, no. 2 (2019): 52–72. http://dx.doi.org/10.21664/2238-8869.2019v8i2.p52-72.

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Biodegradable polymers are in areas such as pharmaceutical, food and bioremediation processes. Isolation, characterization (SEM, FTIR, TGA, Monosaccharide Composition, Zeta Potential), antimicrobial activity and toxicity to Artemia salina and Allium cepa L. from the in natura gummy exudate of Terminalia argentea (GTa) are presented herein. The data show irregular morphology and depressions, bands in 1770, 2112, 1354 cm-1, indicating groups of polysaccharides, amphiphilic character, thermo-degradation above 300 ° C and low water activity (0.6). The assays were negative for S. aureus and E. coli

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Barokah, Giri Rohmad, Bustami Ibrahim, and Tati Nurhayati. "Characterization Microencapsul Pepton from Spoiled By Catch Fish Using Spray Drying Methods." Jurnal Pengolahan Hasil Perikanan Indonesia 20, no. 2 (2017): 401. http://dx.doi.org/10.17844/jphpi.v20i2.18108.

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Spoiled by catch fish is one of catch produce that have low economic value. Utilization and how to increase the selling value of byproducts by making peptone. Peptone fish is a derivative product or derivative of a water-soluble protein hydrolyzate and does not undergo any coagulation process in hot water. This research aim is to produce peptone with spoiled by catch fish as raw materials using microencapsulation technique and maltodextrin as coating ingredients. Microencapsulate of peptone has a chemical composition with moisture content 8.95%, ash content 5.26%, protein content 62.79%, Fat c

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Souza, Aline Habibe de, Mylla F. C. de Moura, Rafaelle C. B. Franson, et al. "Selection of Yarrowia lipolytica Lipases for Efficient Ester Synthesis or Hydrolysis." Reactions 5, no. 4 (2024): 1027–41. https://doi.org/10.3390/reactions5040054.

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The species Yarrowia lipolytica is an aerobic yeast that produces different lipase isoforms, including extracellular, intracellular, and membrane-bound ones. The immobilization of lipases, such as those from Y. lipolytica, increases enzyme stability and lowers operational costs, through its reuse. The characterization of those biocatalysts is highly important to orientate their technological applications. The present work aims to obtain different Y. lipolytica lipases, through fermentation and immobilization techniques, and to evaluate the ester synthesis and hydrolysis activity of these bioca

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Yang, Yipeng, Emmanuel C. Opara, Yingbin Liu, Anthony Atala, and Weixin Zhao. "Microencapsulation of porcine thyroid cell organoids within a polymer microcapsule construct." Experimental Biology and Medicine 242, no. 3 (2016): 286–96. http://dx.doi.org/10.1177/1535370216673746.

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Hypothyroidism is a common condition of hormone deficiency, and oral administration of thyroid hormones is currently the only available treatment option. However, there are some disadvantages with this treatment modality including compliance challenges to patients. Therefore, a physiologically based alternative therapy for hypothyroidism with little or no side-effects is needed. In this study, we have developed a method for microencapsulating porcine thyroid cells as a thyroid hormone replacement approach. The hybrid wall of the polymer microcapsules permits thyroid hormone release while preve

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Hayatunnufus, Rahmi, Galuh Putri Erika Wati та Emil Budianto. "Preparation, Characterization, and Encapsulation Efficiency Test of Simvastatin Microencapsulation Using Polyblend of Poly(Lactic Acid)and Poly(ɛ-Caprolactone)". Materials Science Forum 947 (березень 2019): 21–25. http://dx.doi.org/10.4028/www.scientific.net/msf.947.21.

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Simvastatin is one of the most extensively used drugs to reduce blood cholesterol levels, which practically insoluble in water and not well absorbed from the gastrointestinal tract. In this study, simvastatin was encapsulated using polyblend of PLA and PCL in the composition of 60:40 by solvent evaporation technique (oil-in-water). The optimization of agitation rate, solvent removal time, emulsion time, and emulsifier concentration have been conducted to obtain the maximum efficiency to encapsulate simvastatin in the matrix polymer. The result showed that the optimum conditions to increase the

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Brito, Giovanna Oliveira de, Bruna Cabral Reis, Eduardo A. Ferreira, et al. "Phenolic Compound Profile by UPLC-MS/MS and Encapsulation with Chitosan of Spondias mombin L. Fruit Peel Extract from Cerrado Hotspot—Brazil." Molecules 27, no. 8 (2022): 2382. http://dx.doi.org/10.3390/molecules27082382.

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Taperebá (Spondias mombin L.) is a native species of the Brazilian Cerrado that has shown important characteristics such as a significant phenolic compound content and biological activities. The present study aimed to characterize the phenolic compound profile and antioxidant activity in taperebá peel extract, as well as microencapsulating the extract with chitosan and evaluating the stability of the microparticles. The evaluation of the profile of phenolic compounds was carried out by UPLC-MS/MS. The in vitro antioxidant activity was evaluated by DPPH and ABTS methods. The microparticles were

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Noviendri, Dedi. "Microencapsulation of Fucoxanthin by Water-in-Oil-in-Water (W/O/W) Double Emulsion Solvent Evaporation Method: A Review." Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology 9, no. 3 (2014): 137. http://dx.doi.org/10.15578/squalen.v9i3.114.

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Fucoxanthin is a major xanthophyll present in brown seaweeds such as Sargassum binderi, S. duplicatum, Turbinaria turbinata, Padina australis, Undaria pinnatifida and Hijkia fusiformis. This carotenoid has a unique structure including oxygenic functional group such as, two hydroxy, keto, epoxy (5,6-monoepoxide), and an allenic bond. Fucoxanthin has some anticancer activities such as, exhibits inhibitory property on colon cancer cells and human hepatic carcinoma HepG2 cell line. This xanthophyll also induces apoptosis of human leukemia cancer HL-60 cells, human prostate cancer PC-3 cell, human

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Kowalska, Ewa, Małgorzata Ziarno, Adam Ekielski, and Tomasz Żelaziński. "Materials Used for the Microencapsulation of Probiotic Bacteria in the Food Industry." Molecules 27, no. 10 (2022): 3321. http://dx.doi.org/10.3390/molecules27103321.

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Probiotics and probiotic therapy have been rapidly developing in recent years due to an increasing number of people suffering from digestive system disorders and diseases related to intestinal dysbiosis. Owing to their activity in the intestines, including the production of short-chain fatty acids, probiotic strains of lactic acid bacteria can have a significant therapeutic effect. The activity of probiotic strains is likely reduced by their loss of viability during gastrointestinal transit. To overcome this drawback, researchers have proposed the process of microencapsulation, which increases

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Berbel Manaia, Eloísa, Marina Paiva Abuçafy, Bruna Galdorfini Chiari-Andréo, Bruna Lallo Silva, João Augusto Oshiro-Júnior, and Leila Chiavacci. "Physicochemical characterization of drug nanocarriers." International Journal of Nanomedicine Volume 12 (July 2017): 4991–5011. http://dx.doi.org/10.2147/ijn.s133832.

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