Academic literature on the topic 'Checkpoints'

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Journal articles on the topic "Checkpoints"

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PAUN, MIHAELA, NICHAMON NAKSINEHABOON, RAJA NASSAR, CHOKCHAI LEANGSUKSUN, STEPHEN L. SCOTT, and NARATE TAERAT. "INCREMENTAL CHECKPOINT SCHEMES FOR WEIBULL FAILURE DISTRIBUTION." International Journal of Foundations of Computer Science 21, no. 03 (2010): 329–44. http://dx.doi.org/10.1142/s0129054110007283.

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Incremental checkpoint mechanism was introduced to reduce high checkpoint overhead of regular (full) checkpointing, especially in high-performance computing systems. To gain an extra advantage from the incremental checkpoint technique, we propose an optimal checkpoint frequency function that globally minimizes the expected wasted time of the incremental checkpoint mechanism. Also, the re-computing time coefficient used to approximate the re-computing time is derived. Moreover, to reduce the complexity in the recovery state, full checkpoints are performed from time to time. In this paper we pre
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Islam, Tanzima Zerin, Kathryn Mohror, Saurabh Bagchi, Adam Moody, Bronis R. de Supinski, and Rudolf Eigenmann. "McrEngine: A Scalable Checkpointing System Using Data-Aware Aggregation and Compression." Scientific Programming 21, no. 3-4 (2013): 149–63. http://dx.doi.org/10.1155/2013/341672.

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High performance computing (HPC) systems use checkpoint-restart to tolerate failures. Typically, applications store their states in checkpoints on a parallel file system (PFS). As applications scale up, checkpoint-restart incurs high overheads due to contention for PFS resources. The high overheads force large-scale applications to reduce checkpoint frequency, which means more compute time is lost in the event of failure. We alleviate this problem through a scalable checkpoint-restart system, mcrEngine. McrEngine aggregates checkpoints from multiple application processes with knowledge of the
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Rhind, Nicholas, and Paul Russell. "Roles of the Mitotic Inhibitors Wee1 and Mik1 in the G2 DNA Damage and Replication Checkpoints." Molecular and Cellular Biology 21, no. 5 (2001): 1499–508. http://dx.doi.org/10.1128/mcb.21.5.1499-1508.2001.

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ABSTRACT The G2 DNA damage and DNA replication checkpoints in many organisms act through the inhibitory phosphorylation of Cdc2 on tyrosine-15. This phosphorylation is catalyzed by the Wee1/Mik1 family of kinases. However, the in vivo role of these kinases in checkpoint regulation has been unclear. We show that, in the fission yeastSchizosaccharomyces pombe, Mik1 is a target of both checkpoints and that the regulation of Mik1 is, on its own, sufficient to delay mitosis in response to the checkpoints. Mik1 appears to have two roles in the DNA damage checkpoint; one in the establishment of the c
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Cai, Huiming, Ge Liu, Jianfeng Zhong, et al. "Immune Checkpoints in Viral Infections." Viruses 12, no. 9 (2020): 1051. http://dx.doi.org/10.3390/v12091051.

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As evidence has mounted that virus-infected cells, such as cancer cells, negatively regulate the function of T-cells via immune checkpoints, it has become increasingly clear that viral infections similarly exploit immune checkpoints as an immune system escape mechanism. Although immune checkpoint therapy has been successfully used in cancer treatment, numerous studies have suggested that such therapy may also be highly relevant for treating viral infection, especially chronic viral infections. However, it has not yet been applied in this manner. Here, we reviewed recent findings regarding immu
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Kappas, Nicholas C., Pamela Savage, Katherine C. Chen, Allan T. Walls, and Jill C. Sible. "Dissection of the XChk1 Signaling Pathway in Xenopus laevis Embryos." Molecular Biology of the Cell 11, no. 9 (2000): 3101–8. http://dx.doi.org/10.1091/mbc.11.9.3101.

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Checkpoint pathways inhibit cyclin-dependent kinases (Cdks) to arrest cell cycles when DNA is damaged or unreplicated. Early embryonic cell cycles of Xenopus laevis lack these checkpoints. Completion of 12 divisions marks the midblastula transition (MBT), when the cell cycle lengthens, acquiring gap phases and checkpoints of a somatic cell cycle. Although Xenopus embryos lack checkpoints prior to the MBT, checkpoints are observed in cell-free egg extracts supplemented with sperm nuclei. These checkpoints depend upon the Xenopus Chk1 (XChk1)-signaling pathway. To understand why Xenopus embryos
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Nabieva, Malika. "DEVELOPMENT OF CUSTOMS SERVICE MECHANISMS IN THE CONTEXT OF INTELLIGENT CHECKPOINTS." Russian Journal of Management 12, no. 4 (2025): 703–15. https://doi.org/10.29039/2500-1469-2024-12-4-703-715.

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The paper presents the results of an analysis of the development of intelligent checkpoint technologies in the context of their potential impact on the development of customs services at an intelligent checkpoint. The analysis of the current state of research aimed at improving the efficiency of checkpoints shows the presence of only individual functional solutions that pointwise implement fragmented tasks of instrumental control at checkpoints outside of complex solutions that integrate well-known technical solutions and select and implement advanced technologies of instrumental control in th
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Heideker, Johanna, Ewa T. Lis, and Floyd E. Romesberg. "Phosphatases, DNA Damage Checkpoints and Checkpoint Deactivation." Cell Cycle 6, no. 24 (2007): 3058–64. http://dx.doi.org/10.4161/cc.6.24.5100.

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Belevich, A. S., M. I. Yarmolinskaya, S. A. Selkov та D. I. Sokolov. "Immune сheckpoints in the context of external genital endometriosis". Medical Immunology (Russia) 27, № 2 (2024): 245–64. https://doi.org/10.15789/1563-0625-ici-2923.

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Endometriosis is a chronic recurrent disease with insufficiently studied pathogenesis. Endometriosis is known to share similar features with tumors. Thus, the outgrowth of endometrium-like tissue outside the uterus is the main feature of this condition. The dysfunction of local immune response is required for cell proliferation and invasion in ectopic sites. The involvement of immune checkpoints is among the mechanisms allowing avoidance of immune surveillance shown for the tumors. Immune checkpoints are presented by proteins expressed on immune cells (most on T cells). The checkpoint binding
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GADE, EMILY KALAH. "Social Isolation and Repertoires of Resistance." American Political Science Review 114, no. 2 (2020): 309–25. http://dx.doi.org/10.1017/s0003055420000015.

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Checkpoints in the West Bank’s Hebron Governorate represent Israel’s ever-present power over Palestinian civilians. Drawing on 71 interviews conducted during the Intifada of Individuals (2015), this article inductively builds theory about the relationship between social isolation and different modalities of resistance. Rather than forcing civilians to comply with the state, checkpoint apparatus instead change the nature and texture of resistance. I suggest that checkpoints structure social connections for civilians on the ground. Checkpoint apparatus which inhibit social connection engender a
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Yamada, Ayumi, Brad Duffy, Jennifer A. Perry, and Sally Kornbluth. "DNA replication checkpoint control of Wee1 stability by vertebrate Hsl7." Journal of Cell Biology 167, no. 5 (2004): 841–49. http://dx.doi.org/10.1083/jcb.200406048.

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G2/M checkpoints prevent mitotic entry upon DNA damage or replication inhibition by targeting the Cdc2 regulators Cdc25 and Wee1. Although Wee1 protein stability is regulated by DNA-responsive checkpoints, the vertebrate pathways controlling Wee1 degradation have not been elucidated. In budding yeast, stability of the Wee1 homologue, Swe1, is controlled by a regulatory module consisting of the proteins Hsl1 and Hsl7 (histone synthetic lethal 1 and 7), which are targeted by the morphogenesis checkpoint to prevent Swe1 degradation when budding is inhibited. We report here the identification of X
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Dissertations / Theses on the topic "Checkpoints"

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Ho, Chui Chui. "Characterization of the regulation of p53 and checkpoint kinases in DNA integrity checkpoints /." View abstract or full-text, 2006. http://library.ust.hk/cgi/db/thesis.pl?BICH%202006%20HO.

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Fialho, de Queiroz Leonardo. "Fault Tolerance Configuration for Uncoordinated Checkpoints." Doctoral thesis, Universitat Autònoma de Barcelona, 2011. http://hdl.handle.net/10803/79095.

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La tendencia general de los computadores paralelos es crecer en complejidad y en número de componentes. La miniaturización y la concentración de dichos elementos es la principal causa de la aparición y aumento de los fallos en estos computadores. Asimismo, para permitir la ejecución correcta de las aplicaciones paralelas, existe la necesidad de proveer soporte y de tolerar fallos en estos entornos. Una estrategia amplamente utilizada es el rollback-recovery, que consiste en guardar periódicamente el estado de la aplicación y, en caso de fallos, reanudar la aplicación desde el último estado gu
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Martinsson, Hanna-Stina. "Single cell analysis of checkpoints in G₁ /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-455-4/.

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Thelakkad, Chathoth Keerthi. "An investigation of splicing-dependent transcriptional checkpoints." Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/17547.

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Pre-mRNA splicing and other RNA processing events occur co-transcriptionally. High resolution kinetic studies performed in our lab showed splicing-dependent RNA Pol II (RNA polymerase II) pausing near the 3’ splice site of a reporter gene. Pausing requires splicing, as mutations that block splicing lead to loss of pausing, and restoring splicing restores pausing. It was proposed that RNA Pol II pausing may occur at splicing-dependent transcriptional checkpoints. In this study, I aimed to search for splicing helicases that might couple splicing with transcription. The ts alleles prp5-1 and prp1
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Burgess, Andrew J. "Targeting cell cycle checkpoints to specifically kill cancer /." St. Lucia, Qld, 2004. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17890.pdf.

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Gauger, Michele Ann Sancar Aziz. "Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2007. http://dc.lib.unc.edu/u?/etd,971.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2007.<br>Title from electronic title page (viewed Dec. 18, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Biochemistry and Biophysics." Discipline: Biochemistry and Biophysics; Department/School: Medicine.
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Egger, Tom. "Mutations de la voie ATR-CHK1, réponse au stress réplicatif et cancer." Thesis, Montpellier, 2018. http://www.theses.fr/2018MONTT031.

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Le cancer colorectal est responsable de plus de 17500 décès par an et se situe à la 3ème place des cancers les plus fréquents en France. En altérant le processus de réplication de l’ADN des cellules cancéreuses, certaines des molécules utilisées en chimiothérapie induisent du stress réplicatif. Au niveau cellulaire, ce stress est géré par la voie ATR-CHK1. Quand elle est activée par des régions d’ADN simple brin protégées par RPA au niveau de fourches de réplication ralenties/bloquées, ATR déclenche l’activation du checkpoint intra-S via la phosphorylation de son effecteur CHK1. Ce checkpoint
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Groom, Joanna Ruth School of Medicine UNSW. "Loss of immune regulatory checkpoints in BAFF transgenic mice." Awarded by:University of New South Wales. School of Medicine, 2006. http://handle.unsw.edu.au/1959.4/27281.

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Multiple checkpoints control the survival and activation of auto-reactive B cells. The discovery of the TNF family cytokine BAFF has been crucial to understanding peripheral B cell tolerance mechanisms. Homeostatic levels of BAFF are tightly regulated to maintain tolerance in the periphery. Chronically increased levels of BAFF lead to the survival of autoreactive B cells. Autoimmune patients display elevated serum BAFF levels. BAFF Tg mice model this situation with systemically high levels of BAFF and the subsequent development of two separate but related autoimmune syndromes; systemic lupus e
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Sar, Funda Sancar Aziz. "Understanding the role of Claspin in DNA damage checkpoints." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2006. http://dc.lib.unc.edu/u?/etd,281.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2006.<br>Title from electronic title page (viewed Oct. 10, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Biochemistry and Biophysics." Discipline: Biochemistry and Biophysics; Department/School: Medicine.
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Khan, Salman. "Putting checkpoints to work in thread level speculative execution." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4676.

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With the advent of Chip Multi Processors (CMPs), improving performance relies on the programmers/compilers to expose thread level parallelism to the underlying hardware. Unfortunately, this is a difficult and error-prone process for the programmers, while state of the art compiler techniques are unable to provide significant benefits for many classes of applications. An interesting alternative is offered by systems that support Thread Level Speculation (TLS), which relieve the programmer and compiler from checking for thread dependencies and instead use the hardware to enforce them. Unfortunat
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Books on the topic "Checkpoints"

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Manfredi, James J., ed. Cell Cycle Checkpoints. Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1217-0.

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Li, Willis X., ed. Cell Cycle Checkpoints. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-273-1.

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Joyce, Tim. Cambridge checkpoints 2007. Cambridge University Press, 2006.

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Boydell, S. G. Cambridge checkpoints 2007. Cambridge University Press, 2006.

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Boydell, S. G. Cambridge checkpoints 2007. Cambridge University Press, 2006.

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Boydell, S. G. Cambridge checkpoints 2007. Cambridge University Press, 2006.

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Xu, Jie, ed. Regulation of Cancer Immune Checkpoints. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3266-5.

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Leslie, Taggart, ed. Checkpoints: Developing college English skills. 5th ed. Longman, 2003.

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Page, Jack. Checkpoints: Developing college English skills. 3rd ed. Longman, 1997.

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Page, Jack. Checkpoints: Developing college English skills. 4th ed. Longman, 2001.

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Book chapters on the topic "Checkpoints"

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Willis, Nicholas, and Nicholas Rhind. "Studying G2 DNA Damage Checkpoints Using the Fission Yeast Schizosaccharomyces pombe." In Cell Cycle Checkpoints. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-273-1_1.

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Srinivasan, Seetha V., and Jean Gautier. "Study of Cell Cycle Checkpoints Using Xenopus Cell-Free Extracts." In Cell Cycle Checkpoints. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-273-1_10.

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Day, Tovah A., Chris Sproul, Marila Cordeiro-Stone, and Cyrus Vaziri. "Analyzing DNA Replication Dynamics of Genotoxin-Treated Cells Using Velocity Sedimentation." In Cell Cycle Checkpoints. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-273-1_11.

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Tapia-Alveal, Claudia, and Matthew J. O’Connell. "Methods for Studying Checkpoint Kinases – Chk1." In Cell Cycle Checkpoints. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-273-1_12.

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Shiotani, Bunsyo, and Lee Zou. "A Human Cell Extract-Based Assay for the Activation of ATM and ATR Checkpoint Kinases." In Cell Cycle Checkpoints. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-273-1_13.

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Resnick-Silverman, Lois, and James J. Manfredi. "Analyzing p53 Regulated DNA Damage Checkpoints by Flow Cytometry." In Cell Cycle Checkpoints. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-273-1_14.

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Davidson, Jean M., and Robert J. Duronio. "Using Drosophila S2 Cells to Measure S phase-Coupled Protein Destruction via Flow Cytometry." In Cell Cycle Checkpoints. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-273-1_15.

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DeRan, Michael, Mary Pulvino, and Jiyong Zhao. "Assessing G1-to-S-Phase Progression After Genotoxic Stress." In Cell Cycle Checkpoints. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-273-1_16.

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Keeling, Jacob W. P., and Rita K. Miller. "Indirect Immunofluorescence for Monitoring Spindle Assembly and Disassembly in Yeast." In Cell Cycle Checkpoints. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-273-1_17.

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Wang, Yucai, and Lei Li. "Detecting Recruitment of DNA Damage Response Factors Through the eChIP Approach." In Cell Cycle Checkpoints. Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-273-1_18.

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Conference papers on the topic "Checkpoints"

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Tang, Xinxin, and Xu Zhou. "An Optimized RDMA Scheme for Efficient VM Synchronization in QEMU Checkpoints." In 2025 4th International Symposium on Computer Applications and Information Technology (ISCAIT). IEEE, 2025. https://doi.org/10.1109/iscait64916.2025.11010374.

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Ault, J. Peter. "Coating Inspection Data Reproducibility." In Paint and Coatings Expo (PACE) 2010. SSPC, 2010. https://doi.org/10.5006/s2010-00001.

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Abstract An NSRP-sponsored project investigating the cost of coatings QA suggested that current QA/QC processes have a high tendency to lead to conflict. Survey data collected during the project indicates that one in 20 inspection checkpoints is likely to result in a dispute. Some of these disputes may simply arise from the expected variability in standard coating QA test methods. Data regarding the reproducibility of coating QA measurements is generally not well understood and, in some cases non-existent. The paper will discuss the reproducibility of various measurements used in the industria
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Garcia, Islene C., and Luiz E. Buzato. "Using Common Knowledge to Improve Fixed-Dependency-After-Send." In Workshop de Testes e Tolerância a Falhas. Sociedade Brasileira de Computação - SBC, 2000. http://dx.doi.org/10.5753/wtf.2000.23468.

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Checkpoint patterns that enforce the rollbak-dependency trackability (RDT) property allow effcient solutions to the determination of consistent global checkpoints that include a given set of checkpoints. Fixed-Dependency-After-Send (FDAS) is a well-known RDT protocol that forces the dependency vector of a process to remain unchanged during a checkpoint interval after the first message-send event. In this paper, we explore processes' common knowledge about their behavior to derive a more effcient condition to induce checkpoints under FDAS. We consider that our approach can be used to improve ot
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Goulart, Henrique, Álvaro Franco, and Odorico Mendizabal. "Checkpointing Techniques in Distributed Systems: A Synopsis of Diverse Strategies Over the Last Decades." In Workshop de Testes e Tolerância a Falhas. Sociedade Brasileira de Computação - SBC, 2023. http://dx.doi.org/10.5753/wtf.2023.785.

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This paper concisely reviews checkpointing techniques in distributed systems, focusing on various aspects such as coordinated and uncoordinated checkpointing, incremental checkpoints, fuzzy checkpoints, adaptive checkpoint intervals, and kernel-based and user-space checkpoints. The review highlights interesting points, outlines how each checkpoint approach works, and discusses their advantages and drawbacks. It also provides a brief overview of the adoption of checkpoints in different contexts in distributed computing, including Database Management Systems (DBMS), State Machine Replication (SM
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Pintor, Erick, and Fernando Luís Dotti. "SMaRtTrie: Reducing Checkpoint’s Impact in SMR Systems with a CTrie Data Structure." In Simpósio Brasileiro de Redes de Computadores e Sistemas Distribuídos. Sociedade Brasileira de Computação - SBC, 2021. http://dx.doi.org/10.5753/sbrc.2021.16751.

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State Machine Replication (SMR) is a well-established approach for the development of fault tolerant systems through replication. Durable SMR systems rely on command logging and checkpoints for fast recovery upon failures. However, checkpoints are known to impact service&amp;apos;s throughput as traditional SMR architectures stop serving requests in order to ensure checkpoint consistency. In this paper, we present SMaRtTrie: a simple in-memory key-value storage built on a concurrent trie data structure that supports the creation of consistent checkpoints in parallel with command execution. Exp
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Sakata, Tiemi C., Islene C. Garcia, and Luiz E. Buzato. "Uso de Broadcast na Sincronização de Checkpoints em Protocolos Minimais." In Workshop de Testes e Tolerância a Falhas. Sociedade Brasileira de Computação - SBC, 2004. http://dx.doi.org/10.5753/wtf.2004.23387.

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Nos protocolos de checkpointing síncronos, a aplicação pode ser facilmente restabelecida após a ocorrência de uma falha, pois basta que todos os processos retornem ao seu último checkpoint salvo. Neste artigo, exploramos a classe de protocolos síncronos minimais na qual um número minimal de processos salva checkpoints a cada invocação do protocolo para a construção de um checkpoint global consistente. Cao e Singhal propuseram uma nova abordagem para desenvolver um protocolo minimal que utiliza broadcast para bloquear todos os processos e centralizar a um único processo a tarefa de determinar q
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Cardoso, Paulo Vinicus, Rhauani Weber Aita Fazul, and Patrícia Pitthan Barcelos. "Validação de Políticas para o Estabelecimento Dinâmico de Checkpoints no Apache Spark." In Simpósio Brasileiro de Redes de Computadores e Sistemas Distribuídos. Sociedade Brasileira de Computação, 2020. http://dx.doi.org/10.5753/sbrc.2020.12271.

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O Apache Spark é uma plataforma voltada ao processamento distribuído de dados em memória. Para uma persistência confiável e tolerante a falhas, o Spark usa a técnica de checkpoint. O estabelecimento de checkpoints, entretanto, precisa ser realizado manualmente através do código-fonte, o que dificulta uma configuração eficiente. Esse trabalho apresenta e valida uma arquitetura de configuração dinâmica para checkpoints no Spark. A arquitetura proposta inicia procedimentos de checkpoint automaticamente, com base em políticas de monitoramento que observam o sistema e suas aplicações. Os experiment
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Cardoso, Paulo Vinicius, and Patricia Pitthan Barcelos. "Impacto do Custo de Salvamento e dos Atributos de Configuração no Checkpoint do Apache Hadoop." In XXXVII Simpósio Brasileiro de Redes de Computadores e Sistemas Distribuídos. Sociedade Brasileira de Computação - SBC, 2019. http://dx.doi.org/10.5753/sbrc.2019.7384.

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O framework Apache Hadoop, usado para processar e armazenar grandes quantidades de dados, usa a técnica de Checkpoint and Recovery para auxiliar em recuperações pós-falha de seu sistema de arquivos distribuído. Porém, adaptações eficientes para período entre checkpoints do Hadoop dependem de observações apuradas do sistema. O objetivo deste trabalho é estimar o custo da realização de checkpoints e o tempo médio entre falhas do sistema a partir de um histórico de observações. Os fatores são observados e analisados com relação a diferentes variações de configuração do framework e do benchmark us
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Cao, Guohong, and Mukesh Singhal. "Mutable checkpoints." In the eighteenth annual ACM symposium. ACM Press, 1999. http://dx.doi.org/10.1145/301308.301371.

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Eischer, Michael, Markus Buttner, and Tobias Distler. "Deterministic Fuzzy Checkpoints." In 2019 38th Symposium on Reliable Distributed Systems (SRDS). IEEE, 2019. http://dx.doi.org/10.1109/srds47363.2019.00026.

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Reports on the topic "Checkpoints"

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Klundt, Ruth Ann, Matthew L. Curry, and H. Lee Ward. Using the Sirocco File System for high-bandwidth checkpoints. Office of Scientific and Technical Information (OSTI), 2012. http://dx.doi.org/10.2172/1039010.

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Wang, Bin, and Stephan Elledge. Involvement of 53BP1, a p53 Binding Protein, in Chk2 Phosphorylation of p53 and DNA Damage Cell Cycle Checkpoints. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada426338.

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Wang, Bin, and Stephen J. Elledge. Involvement of 53BP1, a p43 Binding Protein, in Chk2 Phosphorylation of p53 and DNA Damage Cell Cycle Checkpoints. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada417278.

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Zhou, Qingtian, Zewen Jiang, Xinying You, Pin Lin, and Yanfeng Shao. Platelet-to-lymphocyte ratio predicts survival of patients with hepatocellular carcinoma undergoing immune checkpoints inhibitors: A Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.5.0079.

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Berdiqulov, Aziz. ECMI Minorities Blog. Is Uzbekistan Not Ready to Let It Go? Unrest in Karakalpakstan. European Centre for Minority Issues, 2022. http://dx.doi.org/10.53779/kpsa1020.

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In July 2022, unprecedented demonstrations took place in Uzbekistan’s Autonomous Republic of Karakalpakstan. These demonstrations followed proposed constitutional amendments which would remove Karakalpakstan’s right to freely secede from the Uzbek Republic. Thousands of Karakalpaks joined together for peaceful demonstrations to protest against the changes concerning their homeland. Tashkent reacted in line with what seems to have become a Central Asian formula: military troops were sent to suppress the demonstrations, which led to multiple deaths and injuries; the Internet was shut down; curfe
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Buchanan, Randy, Christina Rinaudo, George Gallarno, and M. Lagarde. Early life-cycle prediction of reliability. Engineer Research and Development Center (U.S.), 2023. http://dx.doi.org/10.21079/11681/46919.

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The intent of this project is to investigate a variety of approaches for the development of a basic model for the early life-cycle prediction of reliability (pre-Milestone A). The United States Department of Defense (DoD) currently utilizes an acquisition framework in which system development advances through a series of checkpoints known as milestones. Each milestone represents a decision point, with Milestone A being the earliest in the life cycle. At Milestone A, also known as the risk-reduction decision, the DoD evaluates design concepts while also committing funds to the maturation of tec
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Tan, Kyle, Moana Waitoki, Justin Phillips, and Damian Scarf. Unpacking media narratives: Racism and problematic reasonings. The University of Waikato, 2025. https://doi.org/10.15663/j22.36090.

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In this research brief, we present summaries of four case studies of racism in mainstream and social media in Aotearoa. Through a series of carefully selected datasets sourced from TV episodes (Police TEN 7), print media such as news articles (including Northland checkpoints), and tweets (Three Waters reform), we outline how Māori are represented across these mediums. With an expert in language modelling on our team, we analysed large datasets that give us sufficient statistical power to infer specific Māori discourses on respective platforms. Further, we examined key themes that characterise
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Yan, Miao, Shuang Xia, and Yichang Zhao. Risk of sepsis in cancer patients treated with immune checkpoint inhibitors: a safety meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0174.

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Review question / Objective: The aim of this meta-analysis is to estimate the risk of sepsis in cancer patients treated with immune checkpoint inhibitors in randomized controlled trials (RCTs). Condition being studied: Sepsis-related toxicities in cancer patients received immune checkpoint inhibitors. Information sources: Electronic databases:Medline; Embase; Central; Trial registers: ClinicalTrails.gov. EU Clinical Trials Register. International Clinical Trials Registry Platform. Regarding RCTs for which we had neither available adverse events on ClinicalTrials.gov nor available adverse event
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Britt, Anne. G2 Checkpoint Responses in Arabidopsis. Office of Scientific and Technical Information (OSTI), 2013. http://dx.doi.org/10.2172/1116357.

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Duell, Jason, Paul H. Hargrove, and Eric S. Roman. Requirements for Linux Checkpoint/Restart. Office of Scientific and Technical Information (OSTI), 2002. http://dx.doi.org/10.2172/793773.

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