Academic literature on the topic 'Chemical abstracts'

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Journal articles on the topic "Chemical abstracts"

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OKA, Noriko, and Akio TANAKA. "The exploration of promising compounds linking to Chemical Abstracts®." Journal of Information Processing and Management 47, no. 3 (2004): 175–81. http://dx.doi.org/10.1241/johokanri.47.175.

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Dix, David J. "Abstracts." International Journal of Toxicology 27, no. 6 (November 2008): 405. http://dx.doi.org/10.1080/10915810802571781.

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The U.S. Environmental Protection Agency (EPA), National Toxicology Program (NTP), and National Institutes of Health (NIH) Chemical Genomics Center (NCGC) have complementary research programs designed to improve chemical toxicity evaluations by developing high throughput screening (HTS) methods that evaluate the impact of environmental chemicals on key toxicity pathways. These federal partners are coordinating an extension of the EPA’s ToxCast program, the NTP’s HTS initiative, and the NCGC’s Molecular Libraries Initiative into a collaborative research program focused on identifying toxicity pathways and developing in vitro assays to characterize the ability of chemicals to perturb those pathways. The goal is to develop new paradigm for high throughput toxicity testing that collects mechanistic and quantitative data from in vitro assays measuring chemical modulation of biological processes involved in the progression to toxicity. As toxicity pathways are identified, the in vitro assays can be optimized for comparison to in vivo animal studies, and for predicting effects in humans. Subsequent computational modeling of toxicity pathway responses and appropriate chemical dosimetry will need to be developed to make these predictions relevant for human health risk assessment. This work was reviewed by EPA and approved for publication but does not necessarily reflect official Agency policy. Index Terms: Toxicogenomics, High Throughput Screening/Testing, EPA ToxCast, Chemical Risk Assessment
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Baker, Dale B. "Chemical Abstracts Service's secondary chemical information services." Journal of Chemical Information and Modeling 25, no. 3 (August 1, 1985): 186–91. http://dx.doi.org/10.1021/ci00047a010.

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Wiggins, Gary. "Chemical information science coverage in Chemical Abstracts." Journal of Chemical Information and Modeling 27, no. 1 (February 1, 1987): 1–3. http://dx.doi.org/10.1021/ci00053a001.

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Hamill, Karen A., R. David Nelson, Gerald G. Vander Stouw, and Robert E. Stobaugh. "Chemical Abstracts Service Chemical Registry System. 10. Registration of substances from pre-1965 indexes of Chemical Abstracts." Journal of Chemical Information and Modeling 28, no. 4 (November 1, 1988): 175–79. http://dx.doi.org/10.1021/ci00060a002.

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Somerville, Arleen. "American Chemical Society/Chemical Abstracts Service: Instructional Issues." Issues in Science and Technology Librarianship, no. 6 (May 15, 1993): 829–1094. http://dx.doi.org/10.29173/istl2562.

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Martínez, Luis-Javier. "Chemical Abstracts cumple cien años." El Profesional de la Informacion 16, no. 5 (October 1, 2007): 481–88. http://dx.doi.org/10.3145/epi.2007.sep.11.

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Feather, John, Monica Blake, Stephanie Pilkington, Deborah Goodall, and Steve Morgan. "Book Reviews." Library and Information Research 19, no. 62 (October 26, 2013): 22–29. http://dx.doi.org/10.29173/lirg422.

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Council of Academic and Professional Publishers. University libraries: a report on book and journal spending I978/9 to 1992/93 Losee, Robert N Jr and Worley, Karen A. Research and evaluation for information professionals Allen, Barbara and Livesey, Brian. How to use Biological Abstracts, Chemical Abstracts and Index Chemicus 2nd ed. Strickland-Hodge, Barry. How to use Index Medicus, Psychological Abstracts and Excerpta Medica 2nd ed. Barker, Keith and Lonsdale, Ray (ed). Skills for life? The meaning of value of literacy. Prytherch, Ray. Information management and library science: a guide to the literature. Gurnsey, John. Copyright theft.
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BLACKWOOD, J. E., P. E. JUN BLOWER, S. W. LAYTEN, D. H. LILLIE, A. H. LIPKUS, J. P. PEER, C. QIAN, L. M. STAGGENBORG, and C. E. WATSON. "ChemInform Abstract: Chemical Abstracts Service Chemical Registry System. Part 13. Enhanced Handling of Stereochemistry." ChemInform 22, no. 34 (August 22, 2010): no. http://dx.doi.org/10.1002/chin.199134264.

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Isenberg, Allen C., Joann T. LeMasters, Abe F. Maxwell, and Gerald G. Vander Stouw. "Procedures for sorting chemical names for Chemical Abstracts' indexes." Journal of Chemical Information and Modeling 25, no. 4 (November 1, 1985): 410–12. http://dx.doi.org/10.1021/ci00048a009.

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Dissertations / Theses on the topic "Chemical abstracts"

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Little, James L., Curtis D. Cleven, and Stacy D. Brown. "Identification of “Known Unknowns” Utilizing Accurate Mass Data and Chemical Abstracts Service Databases." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etsu-works/5300.

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Seijas, Nogareda Jazmin. "Determinants of environmental innovation in the German and Swiss chemical industry : with special consideration of environmental regulation /." Zürich : ETH, 2007. http://e-collection.ethbib.ethz.ch/ecol-pool/diss/abstracts/p16918.pdf.

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Dittner, Mark [Verfasser]. "Globally Optimal Catalysts - Computational Optimization Of Abstract Catalytic Embeddings For Arbitrary Chemical Reactions / Mark Dittner." Kiel : Universitätsbibliothek Kiel, 2019. http://d-nb.info/1194929559/34.

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Foerstendorf, H., and R. Steudtner. "International Workshop on Advanced Techniques in Actinide Spectroscopy (ATAS 2012) - Abstract Book." Forschungszentrum Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:d120-qucosa-113379.

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Modern Societies have to consider diverse tasks strongly related to geochemistry sciences. Examples intensively discussed in the public are restoration measures for contaminated industrial fallow grounds, the safe storage of chemical-toxic and radioactive waste, carbon dioxide sequestration to reduce green-house gas emissions, the construction and operation of deep geothermal power plants, the geochemical exploration of natural resources or water and waste water treatments, including desalination efforts. Direct and urgent aspects to be dealt with are analytical and geochemical consequences of the Fukushima Daiichi nuclear disaster. All these cases have one in common – they require reliable thermodynamic data in order to forecast the fate of chemicals in the respective environment. Whereas a variety of standard methods, such as potentiometry, solubility studies, liquid-liquid extraction or electrochemical titrations, are in widespread use to generate thermodynamic data, it is far less straightforward to assign correct reaction pathways and structural patterns to the underlying chemical transformations. This especially holds for systems with strong tendencies to complexation and oligomerization. Here, it is essential to have proof of evidence for all involved species, which cannot be provided by the aforementioned methods, and is still lacking for various metal-containing systems. Spectroscopic techniques in combination with approaches from quantum chemistry can be of great benefit for such tasks. However, their application ranges are often restricted with respect to the type of element (and redox state) that can be probed. Further handicaps are imposed by detection limits or other parameters such as pH or salinity. Moreover, the spectroscopic results are often difficult to interpret in an unambiguous way. To overcome these complications at least partially, this workshop has been initiated. It shall significantly extend the application areas of spectroscopic tools important for lanthanide and actinide chemistry. Emphasis shall be placed on the development of spectroscopic methods towards more challenging environmental conditions – such as very basic pH values, elevated temperatures, pressures, or salinities – extending the range of covered elements and redox states. Furthermore, the exploration of options for lowering detection limits and increasing spatial resolution at sufficiently high signal-to-noise ratios will support future investigations on more complex systems. An approach combining the extension of spectroscopic tools with respect to elements and parameters, improvements of experimental setups, and applications of quantum chemical methods in predictive as well as interpretative ways certainly can be very beneficial. The workshop hopefully will bundle and strengthen respective research activities and ideally act as a nucleus for an international network, closely collaborating with international partners. I am confident that the workshop will deliver many exciting ideas, promote scientific discussions, stimulate new developments and in such a way be successful.
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Foerstendorf, H., and R. Steudtner. "International Workshop on Advanced Techniques in Actinide Spectroscopy (ATAS 2012) - Abstract Book." Helmholtz-Zentrum Dresden-Rossendorf, 2012. https://hzdr.qucosa.de/id/qucosa%3A22162.

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Modern Societies have to consider diverse tasks strongly related to geochemistry sciences. Examples intensively discussed in the public are restoration measures for contaminated industrial fallow grounds, the safe storage of chemical-toxic and radioactive waste, carbon dioxide sequestration to reduce green-house gas emissions, the construction and operation of deep geothermal power plants, the geochemical exploration of natural resources or water and waste water treatments, including desalination efforts. Direct and urgent aspects to be dealt with are analytical and geochemical consequences of the Fukushima Daiichi nuclear disaster. All these cases have one in common – they require reliable thermodynamic data in order to forecast the fate of chemicals in the respective environment. Whereas a variety of standard methods, such as potentiometry, solubility studies, liquid-liquid extraction or electrochemical titrations, are in widespread use to generate thermodynamic data, it is far less straightforward to assign correct reaction pathways and structural patterns to the underlying chemical transformations. This especially holds for systems with strong tendencies to complexation and oligomerization. Here, it is essential to have proof of evidence for all involved species, which cannot be provided by the aforementioned methods, and is still lacking for various metal-containing systems. Spectroscopic techniques in combination with approaches from quantum chemistry can be of great benefit for such tasks. However, their application ranges are often restricted with respect to the type of element (and redox state) that can be probed. Further handicaps are imposed by detection limits or other parameters such as pH or salinity. Moreover, the spectroscopic results are often difficult to interpret in an unambiguous way. To overcome these complications at least partially, this workshop has been initiated. It shall significantly extend the application areas of spectroscopic tools important for lanthanide and actinide chemistry. Emphasis shall be placed on the development of spectroscopic methods towards more challenging environmental conditions – such as very basic pH values, elevated temperatures, pressures, or salinities – extending the range of covered elements and redox states. Furthermore, the exploration of options for lowering detection limits and increasing spatial resolution at sufficiently high signal-to-noise ratios will support future investigations on more complex systems. An approach combining the extension of spectroscopic tools with respect to elements and parameters, improvements of experimental setups, and applications of quantum chemical methods in predictive as well as interpretative ways certainly can be very beneficial. The workshop hopefully will bundle and strengthen respective research activities and ideally act as a nucleus for an international network, closely collaborating with international partners. I am confident that the workshop will deliver many exciting ideas, promote scientific discussions, stimulate new developments and in such a way be successful.
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Caumont-Potdevin, Audrey. "Synthèse par voie sol-gel et caractérisation de matériaux luminescents nanostructurés applicables dans une nouvelle génération de lampes propres." Phd thesis, Université Blaise Pascal - Clermont-Ferrand II, 2007. http://tel.archives-ouvertes.fr/tel-00718049.

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Des aluminates de formulation Ln3Al5O12 (Ln=Y ou Gd) purs ou dopés par les ions Tb3+ et / ou Ce3+ ont été synthétisés sous forme de poudres et de films minces à partir de précurseurs alcoxydes grâce au procédé sol-gel. Les études réalisées par DRX, spectroscopies IR et Raman ont montré que ces phases sont obtenues pures dès 800°C contre 1500°C par les voies de céramisation classiques. Les analyses EXAFS, SAXS et RMN 27Al menées sur les sols, xérogels et poudres cristallisées ont mis en évidence une organisation structurale plus précoce de la matrice aluminate en présence de l'acétylacétone, utilisé comme agent chélatant. Les propriétés optiques des différents échantillons ont été étudiées : les taux optimaux d'ions dopants ont été déterminés sous exitations VUV, UV et bleue. L'ensemble de ce travail montre clairement les potentialités d'applications de ces matériaux dans une nouvelle génération de lampes propres à excitation plasma ou basées sur la technologie des DELs
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Cesco, Arnaldo. "Una proposta di semantica di Go." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/16741/.

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Bornmann, Lutz, Werner Marx, Hermann Schier, Erhard Rahm, Andreas Thor, and Hans-Dieter Daniel. "Convergent validity of bibliometric Google Scholar data in the field of chemistry: Citation counts for papers that were accepted by Angewandte Chemie International Edition or rejected but published elsewhere, using Google Scholar, Science Citation Index, Scopus, and Chemical Abstracts." 2009. https://ul.qucosa.de/id/qucosa%3A32360.

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Examining a comprehensive set of papers (n = 1837) that were accepted for publication by the journal Angewandte Chemie International Edition (one of the prime chemistry journals in the world) or rejected by the journal but then published elsewhere, this study tested the extent to which the use of the freely available database Google Scholar (GS) can be expected to yield valid citation counts in the field of chemistry. Analyses of citations for the set of papers returned by three fee-based databases – Science Citation Index, Scopus, and Chemical Abstracts – were compared to the analysis of citations found using GS data. Whereas the analyses using citations returned by the three fee-based databases show very similar results, the results of the analysis using GS citation data differed greatly from the findings using citations from the fee-based databases. Our study therefore supports, on the one hand, the convergent validity of citation analyses based on data from the fee-based databases and, on the other hand, the lack of convergent validity of the citation analysis based on the GS data.
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Ma, Wanli. "T-Cham : a programming language based on transactions and the Chemical Abstract Machine." Phd thesis, 2001. http://hdl.handle.net/1885/148085.

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Mathews, Joshua Benjamin. "Micro-probe for physical and chemical surface analysis /." 2001. http://www.library.umaine.edu/theses/theses.asp?Cmd=abstract&ID=CHE2001-001.

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Books on the topic "Chemical abstracts"

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Allan, Barbara. How to use Biological abstracts, Chemical abstracts, Index chemicus. 2nd ed. Aldershot: Gower, 1994.

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Allan, Barbara. How to use Biological abstracts, Chemical abstracts, and Index chemicus. 2nd ed. Aldershot, Hampshire, England: Gower, 1994.

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Chemistry, Royal Society of, ed. Chemical engineering abstracts, (incorporating Theoretical chemical engineering abstracts): Database user-aid manual. London: Royal Society of Chemistry, 1988.

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Livesey, Brian. How to use Chemical abstracts, Current abstracts of chemistry, and Index chemicus. Aldershot, Hants., England: Gower, 1987.

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Royal Society of Chemistry (Great Britain). Theoretical chemical engineering. Cambridge, UK: Royal Society of Chemistry, 1991.

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American Chemical Society. Chemical Abstracts Service., ed. Chemical abstracts : index guide, 1992-1996. Columbus, OH: American Chemical Society, Chemical Abstracts Service, 1997.

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Service, American Chemical Society Chemical Abstracts. Subject coverage and arrangement of abstracts by sections in Chemical abstracts. Columbus, Ohio: Chemical Abstracts Service, 1987.

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American Chemical Society Chemical Abstracts Service. Subject coverage and arrangement of abstracts by sections in Chemical abstracts. Columbus, Ohio: Chemical Abstracts Service, 1992.

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Chemistry, Royal Society of, ed. Chemical engineering abstracts: Database user-aid manual. London: Royal Society of Chemistry, 1987.

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Chemistry, Royal Society of, ed. Chemical engineering abstracts: Database user-aid manual. London: Royal Society of Chemistry, 1986.

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Book chapters on the topic "Chemical abstracts"

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Weisgerber, D. W. "Chemical Abstracts Service Chemical Substance Index nomenclature." In Chemical Nomenclature, 67–102. Dordrecht: Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-4958-7_3.

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Schulz, Hedda, and Ursula Georgy. "Literaturrecherchen in den Chemical Abstracts." In Von CA bis CAS online, 14–97. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-662-10811-6_2.

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Schulz, Hedda, and Ursula Georgy. "Das Informationssystem des Chemical Abstracts Service." In Von CA bis CAS online, 1–13. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-662-10811-6_1.

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Kircher, B., M. Lieser, and W. Reuss. "Chemical-Abstracts-Service-Registry-Number-Register." In Hagers Handbuch der Pharmazeutischen Praxis, 451–77. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-57008-7_5.

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Khudeir, Nasser, and Walter Reuß. "Chemical Abstracts Service Registry Number Register." In Hagers Handbuch, 927–97. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-57741-3_4.

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Schulz, Hedda, and Ursula Georgy. "Searching for Literature in Chemical Abstracts." In From CA to CAS online, 13–97. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78663-1_2.

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Hill, R. A., H. L. J. Makin, D. N. Kirk, G. M. Murphy, and F. M. Macdonald. "Chemical Abstracts Service Registry Number Index." In Dictionary of Steroids, 215–348. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4899-3310-2_3.

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Yuan, Shengang, Chongzhi Zheng, and Jianhua Yao. "Chemical Abstracts Index Names: Automatic Generation." In Industrial Information and Design Issues, 279–84. Berlin, Heidelberg: Springer Berlin Heidelberg, 1996. http://dx.doi.org/10.1007/978-3-642-80286-7_31.

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Schulz, Hedda, and Ursula Georgy. "The Information System of the Chemical Abstracts Service." In From CA to CAS online, 1–12. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-78663-1_1.

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Schulz, Hedda, and Ursula Georgy. "Die Datenbanken des Chemical Abstracts Service bei sechs Hosts." In Von CA bis CAS online, 275–89. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-662-10811-6_8.

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Conference papers on the topic "Chemical abstracts"

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Mohd Nazri Nur Ainaa, A., N. Ahmat, and S. Kamarozaman Aisyah. "Chemical Constituents of Shorea macroptera Dyer." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608219.

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Behrend, Sabine, Magda Spella, Mario A. A. Pepe, Marina Lianou, Ioanna Giopanou, and Georgios T. Stathopoulos. "Mapping of KRAS mutations during chemical carcinogenesis." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.918.

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Behrend, Sabine J., Magda Spella, Mario A. A. Pepe, Georgia A. Giotopoulou, Marina Lianou, Ioanna Giopanou, Anne-Sophie Lamort, and Georgios T. Stathopoulos. "Mapping of Kras mutations during chemical carcinogenesis." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa660.

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Behrend, S., M. Spella, M. A. A. Pepe, G. A. Giotopoulou, M. Lianou, I. Giopanou, A. Lamort, and G. T. Stathopoulos. "Mapping of Kras mutations during chemical carcinogenesis." In ERS Lung Science Conference 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/23120541.lsc-2021.14.

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Whuang, TY, YJ Wu, and PJ Sung. "Chemical Constituents from the Formosan Octocoral Nephthea columnaris." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608201.

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Jeon, JH, H. Seo Young, K. Jeon Won, MS Kim, D. Lee, M. Ryu Seung, S. Jang Dae, and J. Lee. "Chemical constituents from the groundnuts of Apios americana." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608262.

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Guezguez, Fatma, Sonia Dridi-Dhaouadi, Mohamed Abdelwaheb, Ichraf Anane, Slaheddine Rekik, Saad Saguem, and Sonia Rouatbi. "Chemical characterization of smokeless tobacco products available in Tunisia." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa1687.

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Sabine, Behrend, Magda Spella, Mario A. A. Pepe, Marina Lianou, Ioanna Giopanou, and Georgios T. Stathopoulos. "LSC - 2021 - Mapping of Kras mutations during chemical carcinogenesis." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa1115.

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Ko, HH, CC Chang, CH Lin, YH Kuo, IS Chen, and HS Chang. "Bioactive chemical constituents isolated from the root of Neolitsea acuminatissima." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608145.

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Chaisawadi, Suchada, and Solot Suwanyeun. "PW 1452 Chemical laboratory safety in higher education: case study in kmutt thailand." In Safety 2018 abstracts. BMJ Publishing Group Ltd, 2018. http://dx.doi.org/10.1136/injuryprevention-2018-safety.585.

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Reports on the topic "Chemical abstracts"

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Taylor, John K. A collection of abstracts of selected publications related to quality assurance of chemical measurements. Gaithersburg, MD: National Bureau of Standards, January 1986. http://dx.doi.org/10.6028/nbs.ir.86-3352.

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Herron, John T., Wing Tsang, Stephen E. Stein, and David M. Golden. International Conference on Chemical Kinetics: Program and Abstracts Held in Gaithersburg, Maryland on 17-19 June 1985. Fort Belvoir, VA: Defense Technical Information Center, June 1985. http://dx.doi.org/10.21236/ada182285.

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Verronen, P. T:, ed. 11 th International Workshop on Long-Term Changes and Trends in the Atmosphere, Book of Abstracts. Finnish Meteorological Institute, May 2022. http://dx.doi.org/10.35614/isbn.9789523361577.

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The 11 th International Workshop on Long-Term Changes and Trends in the Atmosphere will be held between 30 May and 3 June, 2022, at the Finnish Meteorological Institute in Helsinki, Finland. The workshop is organised by the Finnish Meteorological Institute. The workshop gathers together more than 50 scientists from the EU, USA, India, Canada, Argentina, Norway, China, Switzerland, and UK. This report is the official abstract book of the workshop. The scientific topics include: ● Stratospheric and mesospheric observations ● Simulations and predictions of the stratosphere and mesosphere ● Changes in the ionosphere and thermosphere ● Dynamic, physical, chemical and radiative mechanisms ● Role of the stratosphere and mesosphere for climate The workshop is sponsored by the International Association of Geomagnetism and Aeronomy (IAGA) and the International Association of Meteorology and Atmospheric Sciences (IAMAS).
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Kennedy, Robert T. Bioinformatics Symposium of the Analytical Division of the American Chemical Society Meeting. Final Technical Report from 03/15/2000 to 03/14/2001 [sample pages of agenda, abstracts, index]. Office of Scientific and Technical Information (OSTI), March 2000. http://dx.doi.org/10.2172/806755.

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Peters, Vanessa, Deblina Pakhira, Latia White, Rita Fennelly-Atkinson, and Barbara Means. Designing Gateway Statistics and Chemistry Courses for Today’s Students: Case Studies of Postsecondary Course Innovations. Digital Promise, August 2022. http://dx.doi.org/10.51388/20.500.12265/162.

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Scholars of teaching and learning examine the impacts of pedagogical decisions on students’ learning and course success. In this report, we describes findings from case studies of eight innovative postsecondary introductory statistics and general chemistry courses that have evidence of improving student completion rates for minoritized and low-income students. The goal of the case studies was to identify the course design elements and pedagogical practices that were implemented by faculty. To identify courses, Digital Promise sought nominations from experts in statistics and chemistry education and reviewed National Science Foundation project abstracts in the Improving Undergraduate STEM Education (IUSE) program. The case studies courses were drawn from 2- and 4-year colleges and were implemented at the level of individual instructors or were part of a department or college-wide intervention. Among the selected courses, both introductory statistics (n = 5) and general chemistry (n = 3) involved changes to the curriculum and pedagogy. Curricular changes involved a shift away from teaching formal mathematical and chemical equations towards teaching that emphasizes conceptual understanding and critical thinking. Pedagogical changes included the implementation of peer-based active learning, formative practice, and supports for students’ metacognitive and self-regulation practices.
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Author, Not Given. Fifteenth Symposium on Biotechnology for Fuels and Chemicals: Program and Abstracts, May 10-14, 1993, Colorado Springs, Colorado. Office of Scientific and Technical Information (OSTI), April 1993. http://dx.doi.org/10.2172/10172911.

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Dickman, Martin B., and Oded Yarden. Genetic and chemical intervention in ROS signaling pathways affecting development and pathogenicity of Sclerotinia sclerotiorum. United States Department of Agriculture, July 2015. http://dx.doi.org/10.32747/2015.7699866.bard.

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Abstract: The long-term goals of our research are to understand the regulation of sclerotial development and pathogenicity in S. sclerotior11111. The focus in this project was on the elucidation of the signaling events and environmental cues involved in the regulation of these processes, utilizing and continuously developing tools our research groups have established and/or adapted for analysis of S. sclerotiorum, Our stated objectives: To take advantage of the recent conceptual (ROS/PPs signaling) and technical (amenability of S. sclerotiorumto manipulations coupled with chemical genomics and next generation sequencing) developments to address and extend our fundamental and potentially applicable knowledge of the following questions concerning the involvement of REDOX signaling and protein dephosphorylation in the regulation of hyphal/sclerotial development and pathogenicity of S. sclerotiorum: (i) How do defects in genes involved in ROS signaling affect S. sclerotiorumdevelopment and pathogenicity? (ii) In what manner do phosphotyrosinephosphatases affect S. sclerotiorumdevelopment and pathogenicity and how are they linked with ROS and other signaling pathways? And (iii) What is the nature of activity of newly identified compounds that affect S. sclerotiori,111 growth? What are the fungal targets and do they interfere with ROS signaling? We have met a significant portion of the specific goals set in our research project. Much of our work has been published. Briefly. we can summarize that: (a) Silencing of SsNox1(NADPHoxidase) expression indicated a central role for this enzyme in both virulence and pathogenic development, while inactivation of the SsNox2 gene resulted in limited sclerotial development, but the organism remained fully pathogenic. (b) A catalase gene (Scatl), whose expression was highly induced during host infection is involved in hyphal growth, branching, sclerotia formation and infection. (c) Protein tyrosine phosphatase l (ptpl) is required for sclerotial development and is involved in fungal infection. (d) Deletion of a superoxidedismutase gene (Sssodl) significantly reduced in virulence on both tomato and tobacco plants yet pathogenicity was mostly restored following supplementation with oxalate. (e) We have participated in comparative genome sequence analysis of S. sclerotiorumand B. cinerea. (f) S. sclerotiorumexhibits a potential switch between biotrophic and necrotrophic lifestyles (g) During plant­ microbe interactions cell death can occur in both resistant and susceptible events. Non­ pathogenic fungal mutants S. sclerotior111n also cause a cell death but with opposing results. We investigated PCD in more detail and showed that, although PCD occurs in both circumstances they exhibit distinctly different features. The mutants trigger a restricted cell death phenotype in the host that unexpectedly exhibits markers associated with the plant hypersensitive (resistant) response. Using electron and fluorescence microscopy, chemical effectors and reverse genetics, we have established that this restricted cell death is autophagic. Inhibition of autophagy rescued the non-pathogenic mutant phenotype. These findings indicate that autophagy is a defense response in this interaction Thus the control of cell death, dictated by the plant (autophagy) סr the fungus (apoptosis), is decisive to the outcome of certain plant­ microbe interactions. In addition to the time and efforts invested towards reaching the specific goals mentioned, both Pls have initiated utilizing (as stated as an objective in our proposal) state of the art RNA-seq tools in order to harness this technology for the study of S. sclerotiorum. The Pls have met twice (in Israel and in the US), in order to discuss .נחd coordinate the research efforts. This included a working visit at the US Pls laboratory for performing RNA-seq experiments and data analysis as well as working on a joint publication (now published). The work we have performed expands our understanding of the fundamental biology (developmental and pathogenic) of S. sclerotioז111וז. Furthermore, based on our results we have now reached the conclusion that this fungus is not a bona fide necrotroph, but can also display a biotrophic lifestyle at the early phases of infection. The data obtained can eventually serve .נ basis of rational intervention with the disease cycle of this pathogen.
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