Journal articles on the topic 'Chemical process control. Quality of products. Multivariate analysis'

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1

Jin, Li Qiang, and Qing Hua Xu. "Application of near Infrared Spectroscopy and Multivariate Analysis in the Forest Products Industry." Advanced Materials Research 236-238 (May 2011): 1098–102. http://dx.doi.org/10.4028/www.scientific.net/amr.236-238.1098.

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Near infrared (NIR) spectroscopy has received a great deal of attention in forest products industry. The physical, mechanical and chemical properties of inorganic materials can be predicted using the NIR spectroscopy and multivariate analysis (MVA). NIR spectroscopy is suitable for quantitative analysis, especially the process monitoring and quality control. The present paper reviews the application of NIR spectroscopy and MVA in the forest products industry, such as tree improvement and silviculture, pulp and paper, lumber products and the online monitoring.
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Indrayanto, Gunawan. "Recent Development of Quality Control Methods for Herbal Derived Drug Preparations." Natural Product Communications 13, no. 12 (2018): 1934578X1801301. http://dx.doi.org/10.1177/1934578x1801301208.

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Pharmaceutical industries should apply rigorous QC (quality control) to ensure the consistency, safety, and efficacy of their herbal derived drug-preparations. QC must be performed at every stage of the production line i.e. incoming raw materials, extractions, in-process control, finished products and keeping samples. Due to the complex nature of the chemical content of herbal drugs, two approaches to QC should be taken, that is quantitative determination of the selected marker(s) compound(s), and metabolite profiling. Contamination of herbal medicines by heavy metals, pesticides, toxic metabo
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Pereira, Ana C., Marco S. Reis, and Pedro M. Saraiva. "Quality Control of Food Products using Image Analysis and Multivariate Statistical Tools." Industrial & Engineering Chemistry Research 48, no. 2 (2009): 988–98. http://dx.doi.org/10.1021/ie071610b.

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YAMADA, SHIGERU, and AKIHIRO KAWAHARA. "STATISTICAL ANALYSIS OF PROCESS MONITORING DATA FOR SOFTWARE PROCESS IMPROVEMENT." International Journal of Reliability, Quality and Safety Engineering 16, no. 05 (2009): 435–51. http://dx.doi.org/10.1142/s0218539309003484.

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In recent years, software development has become more large-scaled, complicated, and diversified. At the same time, customer requirement of high quality and shortened delivery has increased. Therefore, we have to manage process quality and control product quality in the early-stage of software development in order to produce highly quality software products during the limited period. In this paper, we conduct multivariate linear analyses by using process monitoring data, derive effective process factors affecting the final product quality, and discuss the significant process factors with respe
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Kristy, Nathasa Erdya, Mustafid Mustafid, and Sudarno Sudarno. "PENERAPAN IMPROVED GENERALIZED VARIANCE PADA PENGENDALIAN KUALITAS PAVING BLOCK SEGIENAM." Jurnal Gaussian 9, no. 1 (2020): 87–97. http://dx.doi.org/10.14710/j.gauss.v9i1.27526.

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In quality assurance of hexagonal paving block products, quality control is needed so the products that produced are in accordance with the specified standards. Quality control carried out involves two interconnected quality characteristics, that is thickness and weight of hexagonal paving blocks, so multivariate control chart is used. Improved Generalized Variance control chart is a tool used to control process variability in multivariate manner. Variability needs to be controlled because of in a production process, sometimes there are variabilities that caused by engine problems, operator er
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Prakhova, T. N., A. A. Gavshina, O. L. Lyubimtseva, and E. G. Yumatova. "ORGANIZATION OF QUALITY CONTROL AND DIAGNOSTICS PRODUCTION OF STYRENE-ACRYLIC DISPERSION USING ANALYSIS OF VARIANCE." Kontrol'. Diagnostika, no. 254 (2019): 42–47. http://dx.doi.org/10.14489/td.2019.08.pp.042-047.

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The production of styrene-acrylic dispersion is a complex technological process, which requires constant monitoring. The organization of product quality control has become the main part of the production process and is aimed not only at identifying defects or defective finished products, but also at diagnosing the quality of products in the process of their production, which ensures the advantage of the product in the market and also contributes to its successful marketing. competitive conditions. In various publications, the topic of controlling the process of styrene-acrylic dispersion produ
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Sensiani, Sensiani, Tatik Widiharih, and Rita Rahmawati. "GRAFIK PENGENDALI MULTIVARIATE EXPONENTIALLY WEIGHTED MOVING COVARIANCE MATRIX (MEWMC) PADA DATA SAMPEL ZAT KANDUNGAN BATU BARA (Studi Kasus : PT Bukit Asam (Persero) Tbk. Tahun 2016)." Jurnal Gaussian 9, no. 1 (2020): 1–15. http://dx.doi.org/10.14710/j.gauss.v9i1.27517.

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The progress of industrial business in the midst of global competition increased rapidly. A businessman should have special treatment for their products to compete of market quality. The quality of product is an important factor in choosing a product or service, particularly for the costumers. In technological development, the factors of failure in the product can be minimized by Statistical Quality Control. Besides to reducing diversity in product characteristics, statistical quality control can increase business income. The data source of this research is sekunder sample data of coal product
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Salleh, Rohayu Mohd, Ng Jin Chuan, and Sabariah Saharan. "Monitoring Process Variability and Root Cause Analysis in Paper Box Production." International Journal of Engineering & Technology 7, no. 4.30 (2018): 492. http://dx.doi.org/10.14419/ijet.v7i4.30.22377.

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In this paper, monitoring procedure for process variability in multivariate setting based on individual observations which is a combination of (i) Hotelling’s T2 control chart in detecting out of control signal and (ii) implementation of Mason, Young and Tracy (MYT) decomposition and structure analysis technique for root cause analysis is introduced. The advantages of this procedure will be shown by using the case of a paper box production process in one of the Malaysian manufacturing companies. The successful application of this multivariate approach could act as a stimulant for most industri
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Sany, Mifta Fara, Rukun Santoso, and Arief Rachman Hakim. "PENERAPAN PENGENDALIAN KUALITAS DENGAN MEWMA DAN FUNGSI DENSITAS KERNEL MULTIVARIAT (Studi Kasus: PT Sukorejo Indah Textile Kab. Batang)." Jurnal Gaussian 8, no. 1 (2019): 46–57. http://dx.doi.org/10.14710/j.gauss.v8i1.26621.

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In an era of industrial revolution 4.0, technology is increasingly sophisticated, requiring companies to be more creative. Product quality control is an effort to minimize the defective products produced by the company. The production of weaving sarongs at PT SUKORINTEX pays attention to the accuracy of the length and width of the sarong to conform to the standards set by the company. To find out the quality of woven sarong products at PT SUKORINTEX, analysis was performed using Multivariate Exponentially Weighted Moving Average (MEWMA) control charts and multivariate kernel control charts. Th
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Pavlovic, Aleksandar, Ljubisa Ignjatovic, Sasa Popov, Aleksandar Mladenovic, and Igor Stankovic. "Application of gas chromatography analysis to quality control of residual organic solvents in clopidogrel bisulphate." Journal of the Serbian Chemical Society 79, no. 10 (2014): 1279–93. http://dx.doi.org/10.2298/jsc131120013p.

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A direct-injection, split-mode capillary gas chromatographic procedure with a flame ionization detection is developed for the analysis of eight solvents used in the synthesis and purification of an anti-thrombotic drug clopidogrel bisulphate. The solvents analyzed were methanol, acetone, dichloromethane (DCM), 2-butanol, cyclohexane, toluene, acetic acid and N, N-dimethyl formamide (DMF). In addition, as a result of dehydration of 2-butanol during drying process, in clopidogrel bisulphate samples, significant amounts of 2-butanol dehydration products (1-butene, cis and trans isomers of 2-buten
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Arifa, Abdiyasti Nurul, Rukun Santoso, and Tatik Widiharih. "PERBANDINGAN DIAGRAM KONTROL MEWMA DAN DIAGRAM KONTROL T2 HOTELLING UNTUK PENGENDALIAN KUALITAS PRODUK KAIN POLYESTER (Studi Kasus : PT Daya Manunggal Kota Salatiga)." Jurnal Gaussian 8, no. 1 (2019): 12–23. http://dx.doi.org/10.14710/j.gauss.v8i1.26618.

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Fabrics is one of the most important needs of human life, so demand for clothing is greatly increased. Polyester fabric is a superior product at PT Daya Manunggal Salatiga because it has good quality. The quality of the fabric is very important because it is very influential in the competition to attract consumer interest. To maintain the consistency of the quality of the products produced in accordance with specifications, it is necessary to control the quality of the production process. The quality characteristics used in the production process of polyester fabric are thick layers, thin laye
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Lizarelli, Fabiane Letícia, Nayara Cristini Bessi, Pedro Carlos Oprime, Roniberto Morato do Amaral, and Subhabrata Chakraborti. "A bibliometric analysis of 50 years of worldwide research on statistical process control." Gestão & Produção 23, no. 4 (2016): 853–70. http://dx.doi.org/10.1590/0104-530x1649-15.

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Abstract An increasing number of papers on statistical process control (SPC) has emerged in the last fifty years, especially in the last fifteen years. This may be attributed to the increased global competitiveness generated by innovation and the continuous improvement of products and processes. In this sense, SPC has a fundamentally important role in quality and production systems. The research in this paper considers the context of technological improvement and innovation of products and processes to increase corporate competitiveness. There are several other statistical technics and tools f
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Kuchirka, Yu, and E. Volodarsky. "Cement Quality Control By Using Modern Radiation Methods Of Chemical Analysis In The Process Of Its Production." Methods and Objects of Chemical Analysis Vol. 14, No.1 (2019): 15–20. http://dx.doi.org/10.17721/moca.2019.15-20.

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An essential part of modern quality management system in cement production is state-of-the-art radiation measurement technologies based on methods of neutron activation, X-ray fluorescence and X-ray diffraction chemical analysis of substance. The high speed and accuracy of measuring the characteristics of raw materials and finished products can be achieved by their complex application, thereby ensuring an improving in the level of automation of cement production and the quality of cement in general. The main stages of the portlandcement production process by dry method are considered, includin
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Malwade, Chandrakant R., and Haiyan Qu. "Process Analytical Technology for Crystallization of Active Pharmaceutical Ingredients." Current Pharmaceutical Design 24, no. 21 (2018): 2456–72. http://dx.doi.org/10.2174/1381612824666180629111632.

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Background: Pharmaceutical industry is witnessing increased pressure to introduce innovative and efficient processes for manufacturing Active Pharmaceutical Ingredients (APIs) in order to be competitive as well as to meet the stringent product quality requirements set by regulatory authorities. Crystallization with its ability to engineer the final product to the desired qualities such as purity, polymorphic form, particle size and shape is one of the most important steps involved in the manufacturing of APIs. Therefore, development of crystallization processes with better understanding of pro
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Abubakar Adamu, Umar, Gulumbe Shehu Usman, and Dikko Hussaini Garba. "Multivariate statistical process control approach to monitor quality of chloroquine phosphate tablet (bp250mg) in Dana pharmaceutical company." International Journal of Advanced Statistics and Probability 5, no. 1 (2016): 1. http://dx.doi.org/10.14419/ijasp.v5i1.5713.

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Recently, much attention has been raised on effects of high increase in drugs counterfeiting and sub-standard quality which leads to many casualties in Nigeria. The Multivariate Statistical Process Control Charts approach was employed to examine such defects especially in assessing the official physico-chemical quality of chloroquine phosphate tablet (BP250mg) which claimed to contain the required quality properties. The Multivariate Exponentially Weighted Moving Average (MEWMA) Control Chart gives a powerful and reliable control chart than the widely used Hotelling’s T2˗Control Chart, which d
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Aubakirova, R. A., E. N. Ivashchenko, B. S. Saurbaeva, and G. K. Daumova. "Improvement of the quality of analytical control of metallurgical products as a means of uncertainty." BULLETIN of the L.N. Gumilyov Eurasian National University. Chemistry. Geography. Ecology Series 130, no. 1 (2020): 11–17. http://dx.doi.org/10.32523/2616-6771-2020-130-1-11-17.

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The entire technological process, starting from ore mining to ending with the release of finished products, it is closely connected with the analytical control of each stage. Currently, the practice of analytical laboratories of large metallurgical enterprises, which include the Oskemen Metallurgical Complex LLP "Kazzinc", has firmly entered the physical and chemical or instrumental methods. These methods, which are characterized by rapidity, high selectivity and the ability to simultaneously determine several components, have replaced in most cases chemical ones. The article presents experime
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Shi, Tiannv, Yongmei Guan, Lihua Chen, Shiyu Huang, Weifeng Zhu, and Chen Jin. "Application of Near-Infrared Spectroscopy Analysis Technology to Total Nucleosides Quality Control in the Fermented Cordyceps Powder Production Process." Journal of Analytical Methods in Chemistry 2020 (November 28, 2020): 1–9. http://dx.doi.org/10.1155/2020/8850437.

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Product quality control is a prerequisite for ensuring safety, effectiveness, and stability. However, because of the different strain species and fermentation processes, there was a significant difference in quality. As a result, they should be clearly distinguished in clinical use. Among them, the fermentation process is critical to achieving consistent product quality. This study aims to introduce near-infrared spectroscopy analysis technology into the production process of fermented Cordyceps powder, including strain culture, strain passage, strain fermentation, strain filtration, strain dr
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Huang, Chien-Yi, and Ching-Hsiang Chen. "Improve electromagnetic compatibility of electronic products with multivariate parametric design." Microelectronics International 34, no. 1 (2017): 45–55. http://dx.doi.org/10.1108/mi-11-2015-0088.

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Purpose Differing from previous studies trying to solve the electromagnetic compatibility (EMC) issue by addressing single factor, this study aims to combine measures of shielding, filtering and grounding to design parameters with the Taguchi method at the beginning of product design to come up with the optimal parameter combination. Design/methodology/approach EMC-related performance such as radiated emission, conduction interference and electrical fast transient/burst immunity (EFT) are response variables, whereas the printed circuit board and mechanic design-relevant parameters are consider
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Grevesmuehl, Bernard, Cynthia Kradjel, and Hanno Kellner. "Designing optimized industrial process analysers for closed loop control." Journal of Automatic Chemistry 13, no. 4 (1991): 139–42. http://dx.doi.org/10.1155/s1463924691000263.

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Manufacturers are now looking closely at ways of optimizing ‘quality’ and increasing process efficiency while reducing manufacturing costs. Near infra-red (NIR) technology is a popular solution to this challenge: it provides manufacturers with rapid and reliable in-process analysis and thousands of systems have already been installed in the food, chemical, pharmaceutical and agricultural markets.For over 10 years, NIR has been successfully applied to at-line process analysis. Rugged and easy-to-operate filter analysers are traditionally located in the control room–process operators can then ‘g
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Steinbach, Julia C., Markus Schneider, Otto Hauler, Günter Lorenz, Karsten Rebner, and Andreas Kandelbauer. "A Process Analytical Concept for In-Line FTIR Monitoring of Polysiloxane Formation." Polymers 12, no. 11 (2020): 2473. http://dx.doi.org/10.3390/polym12112473.

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The chemical synthesis of polysiloxanes from monomeric starting materials involves a series of hydrolysis, condensation and modification reactions with complex monomeric and oligomeric reaction mixtures. Real-time monitoring and precise process control of the synthesis process is of great importance to ensure reproducible intermediates and products and can readily be performed by optical spectroscopy. In chemical reactions involving rapid and simultaneous functional group transformations and complex reaction mixtures, however, the spectroscopic signals are often ambiguous due to overlapping ba
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Stankov, Stanko. "Modern control of mineral wool production process." Chemical Industry 67, no. 2 (2013): 375–84. http://dx.doi.org/10.2298/hemind120428069s.

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In this paper, the control of the plant for mineral wool production consisting of a number of the technological units of different sizes and complexity is considered. The application of modern equipment based on PLC (Programmable Logic Controller) and SCADA (Supervisory Control And Data Acquisition) configuration provides optimal control of technological process. Described supervisory and control system is consisting of a number of units doing decentralized distributed control of technological entities where all possible situation are considered during work of machines and devices, which are i
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Kim, Ji Yeon, Myung Hee Chun, and Du Hyung Choi. "Control Strategy for Process Development of High-Shear Wet Granulation and Roller Compaction to Prepare a Combination Drug Using Integrated Quality by Design." Pharmaceutics 13, no. 1 (2021): 80. http://dx.doi.org/10.3390/pharmaceutics13010080.

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In this study, we developed a control strategy for a drug product prepared by high-shear wet granulation and roller compaction using integrated quality by design (QbD). During the first and second stages, we optimized the process parameters through the design of experiments and identified the intermediate quality attributes (IQAs) and critical quality attributes (CQAs) relationship, respectively. In the first stage, we conducted an initial risk assessment by selecting critical process parameters with high impact on IQAs and CQAs and confirmed the correlation between control and response factor
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Kim, Ji Yeon, Myung Hee Chun, and Du Hyung Choi. "Control Strategy for Process Development of High-Shear Wet Granulation and Roller Compaction to Prepare a Combination Drug Using Integrated Quality by Design." Pharmaceutics 13, no. 1 (2021): 80. http://dx.doi.org/10.3390/pharmaceutics13010080.

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In this study, we developed a control strategy for a drug product prepared by high-shear wet granulation and roller compaction using integrated quality by design (QbD). During the first and second stages, we optimized the process parameters through the design of experiments and identified the intermediate quality attributes (IQAs) and critical quality attributes (CQAs) relationship, respectively. In the first stage, we conducted an initial risk assessment by selecting critical process parameters with high impact on IQAs and CQAs and confirmed the correlation between control and response factor
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Amaliah, Nur, and Farida Farida. "Konsep Pengendalian Mutu Pada Pembuatan Permen Jelly Nenas (Ananas Comosus L.)." JSHP : Jurnal Sosial Humaniora dan Pendidikan 3, no. 1 (2019): 39–46. http://dx.doi.org/10.32487/jshp.v3i1.542.

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In the process of processing jelly candy pineapple requires supervision related to food safety and quality assurance. food quality control is one way to get safe and healthy products according to panelists' requests. The aim is to determine the effect of gelling agent on jelly pineapple candy products, to determine the process of making jelly pineapple candy by applying the concept of quality control, and knowing the level of product preference and quality from organoleptic testing. The method used is quantitative qualitative descriptive where the results of the analysis obtained will be descr
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Citraresmi, Ardaneswari Dyah Pitaloka, and F. P. Putri. "PENERAPAN HAZARD ANALYSIS AND CRITICAL CONTROL POINT (HACCP) PADA PROSES PRODUKSI WAFER ROLL [Implementation of Hazard Analysis and Critical Control Point (HACCP) in Production of Wafer Roll]." Jurnal Teknologi & Industri Hasil Pertanian 24, no. 1 (2019): 1. http://dx.doi.org/10.23960/jtihp.v24i1.1-14.

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The purpose of this study was to determine the application of Hazard Analysis and Critical Control Points (HACCP) to identify and prevent potential hazards in the production process of chocolate roll wafers at PT. X. The production process of wafer roll at PT. X consisted of mixing raw materials, filtering, roasting, rolling a wafer roll, filling cream, cutting, decreasing wafer roll temperature, packaging, and X-ray detection. The implementation of a quality assurance system must be carried out at every stage of processes to prevent microbiological chemical, and physical hazard pollution, and
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Rodionova, K. O., and A. P. Paliy. "Analysis and identification of hazardous factors in the technology of manufacture of raw cured sausages." Veterinary Medicine: inter-departmental subject scientific collection, no. 105 (August 7, 2019): 74–80. http://dx.doi.org/10.36016/vm-2019-105-14.

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In Ukraine, the use of HACCP systems (Hazard Analysis and Critical Control Points) is mandatory for all enterprises, which are involved in the process of production or penetration of food products in everyday life. This system is based on the analysis of risks and on the analysis of critical identification of control points in order to prevent the emergence of hazardous situations at any technological stage in the production of meat products. Definition of critical control points and their regular monitoring allow to carry out corrective actions at work timely. The types of hazardous factors t
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Marinkovic, Valentina, Tatjana Sibalija, Vidosav Majstorovic, and Ljiljana Tasic. "Impact analysis of the implemented quality management system on business performances in pharmaceutical-chemical industry in Serbia." Chemical Industry 67, no. 3 (2013): 535–46. http://dx.doi.org/10.2298/hemind120425081m.

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International quality management standard (QMS) ISO 9001 became widely accepted as a framework for product and/or services quality improvement. There are recent research conducted in order to define relationships and effects between the applied QMS and financial and/or non-financial business parameters. The effects of the applied pharmaceutical quality system (PQS) on the business performances in Serbian pharmaceutical-chemical industry are analyzed in this paper using multivariate linear regression analysis. The empirical data were collected using a survey that was performed among experts fro
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Avula, Bharathi, Yan-Hong Wang, Giorgis Isaac, et al. "Metabolic Profiling of Hoodia, Chamomile, Terminalia Species and Evaluation of Commercial Preparations Using Ultrahigh-Performance Liquid Chromatography Quadrupole-Time-of-Flight Mass Spectrometry." Planta Medica 83, no. 16 (2017): 1297–308. http://dx.doi.org/10.1055/s-0043-109239.

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AbstractUltrahigh-performance liquid chromatography quadrupole-time-of-flight mass spectrometry (UHPLC-QToF-MS) profiling was used for the identification of marker compounds and generation of metabolic patterns that could be interrogated using chemometric modeling software. UHPLC-QToF-MS was used to generate comprehensive fingerprints of three botanicals (Hoodia, Terminalia, and chamomile), each having different classes of compounds. Detection of a broad range of ions was carried out in full scan mode in both positive and negative modes over the range m/z 100–1700 using high-resolution mass sp
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KOPONEN, ANTTI, HANNU ELORANTA, ARI JASBERG, MARKUS HONKANEN, and HARRI KIISKINEN. "Real-time monitoring of bubble size distribution in a foam forming process." August 2019 18, no. 8 (2019): 487–94. http://dx.doi.org/10.32964/tj18.8.487.

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Foam forming is an intricate option to lessen fiber flocculation and to get better energy and water efficiency when making fiber-based products. Developed during the 1970s, this approach has recently received renewed attention, mainly because it also offers possibilities to widen the fiber-based product portfolios with novel and more valuable products. In addition to air content, bubble size is the most important property of foam. Foam quality control is essential for building real-world foam forming processes. In this work, we show how bubble size can be monitored with direct optical imaging
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Aikozova, Laura, Ainur Tukibayeva, and Marat Satayev. "Research of the Obtaining Process of Protective Phosphate Nanocoatings." Oriental Journal of Chemistry 35, no. 1 (2019): 228–33. http://dx.doi.org/10.13005/ojc/350127.

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This article presents thermodynamic calculations of the interaction of zinc and iron chlorides with phosphoric acid. The influence of temperature and duration of the interaction on the degree of decomposition of metal chlorides is also determined. It is established that with increasing the temperature and the duration of interaction, the degree of conversion of zinc and iron chlorides to metal phosphates increases and the residual chlorine content in the product simultaneously decreases. The quality control of the obtained products was carried out using physical, chemical and crystal-optical m
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RAJAGOPAL, RAMKUMAR, and ENRIQUE DEL CASTILLO. "AN ANALYSIS AND MIMO EXTENSION OF A DOUBLE EWMA RUN-TO-RUN CONTROLLER FOR NON-SQUARED SYSTEMS." International Journal of Reliability, Quality and Safety Engineering 10, no. 04 (2003): 417–28. http://dx.doi.org/10.1142/s021853930300124x.

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The double EWMA (exponentially weighted moving average) control method is a popular algorithm for adjusting a process from run to run in semiconductor manufacturing. Until recently, the dEWMA controller had been applied only for the single controllable factor (or input), single quality charcteristic (or output) case. Recently, Del Castillo and Rajagopal4 propose a multivariate double EWMA controller for squared multiple-input, multiple-output (MIMO) processes, where there is an equal number of inputs and outputs. This paper extends the MIMO dEWMA controller for non-squared systems. Two differe
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Gao, Ye, Teng Zhang, Yiming Ma, et al. "Application of PAT-Based Feedback Control Approaches in Pharmaceutical Crystallization." Crystals 11, no. 3 (2021): 221. http://dx.doi.org/10.3390/cryst11030221.

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Crystallization is one of the important unit operations for the separation and purification of solid products in the chemical, pharmaceutical, and pesticide industries, especially for realizing high-end, high-value solid products. The precise control of the solution crystallization process determines the polymorph, crystal shape, size, and size distribution of the crystal product, which is of great significance to improve product quality and production efficiency. In order to develop the crystallization process in a scientific method that is based on process parameters and data, process analys
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Zuo, Yamin, Jing Yang, Chen Li, Xuehua Deng, Shengsheng Zhang, and Qing Wu. "Near-Infrared Spectroscopy as a Process Analytical Technology Tool for Monitoring the Steaming Process of Gastrodiae rhizoma with Multiparameters and Chemometrics." Journal of Analytical Methods in Chemistry 2020 (November 4, 2020): 1–12. http://dx.doi.org/10.1155/2020/8847277.

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Steaming is a vital unit operation in traditional Chinese medicine (TCM), which greatly affects the active ingredients and the pharmacological efficacy of the products. Near-infrared (NIR) spectroscopy has already been widely used as a strong process analytical technology (PAT) tool. In this study, the potential usage of NIR spectroscopy to monitor the steaming process of Gastrodiae rhizoma was explored. About 10 lab scale batches were employed to construct quantitative models to determine four chemical ingredients and moisture change during the steaming process. Gastrodin, p-hydroxybenzyl alc
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Mellado-Carretero, J., N. García-Gutiérrez, M. Ferrando, C. Güell, D. García-Gonzalo, and S. De Lamo-Castellví. "Rapid discrimination and classification of edible insect powders using ATR-FTIR spectroscopy combined with multivariate analysis." Journal of Insects as Food and Feed 6, no. 2 (2020): 141–48. http://dx.doi.org/10.3920/jiff2019.0032.

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Insects are being proposed as an alternative way to ensure world’s food and feed security. Methods to determine edible insect powder’s origin and species will be needed for quality control purposes. Infrared spectroscopy has been extensively used in rapid chemical fingerprinting of food products. The present research explores a new approach to discriminate and classify commercial edible insect powders using attenuated total reflectance mid-infrared spectroscopy combined with multivariate analysis. Infrared spectra of seven commercial edible insect powders from different species (Tenebrio molit
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Dalievska, D. Ya, and O. S. Pokotylo. "Physico-chemical indicators of kefir with biologically active iodine in the process of fermentation." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 23, no. 95 (2021): 72–77. http://dx.doi.org/10.32718/nvlvet-f9512.

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Iodine is a natural trace element that is necessary for the human body. The function of iodine in the human body is the synthesis of thyroid hormones. Iodine deficiency has many negative consequences for the human body. Iodine deficiency is especially dangerous for pregnant women and children. Insufficient iodine in pregnant women increases the risk of miscarriage and birth of a child with cognitive impairment. Iodine deficiency in children has the following consequences: delayed physical development, delayed intellectual development, decreased mental activity, drowsiness, lethargy. Expanding
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J. Bowser, Timothy, Mwarumba Mwavita, Ahmed Al-Sakini, William McGlynn, and Niels O. Maness. "Quality and Shelf Life of Fermented Lamb Meat Sausage with Rosemary Extract." Open Food Science Journal 8, no. 1 (2014): 22–31. http://dx.doi.org/10.2174/1874256401408010022.

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Dry fermented lamb-meat sausages were manufactured with 70% lamb meat, 30% lamb fat and rosemary extract under a controlled fermentation and ripening process. The antioxidant effect of three rosemary extract concentrations (0.015, 0.030 and 0.045%) on the oxidation stability, chemical composition, color parameter and sensory acceptability during ripening/drying and storage periods (1, 10, 25, 40 55, 70, 85 and 100 days) was studied. The fermentation process significantly (p 0.05) reduced the moisture content, pH and water activity, while the components of protein, fat and ash increased during
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Loncar, Irma, and Janko Cvijanovic. "Analysis of the importance of drug packaging quality for end users and pharmaceutical industry as a part of the quality management system." Chemical Industry 67, no. 6 (2013): 951–59. http://dx.doi.org/10.2298/hemind121221013l.

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In this study, we collected and analyzed information on the importance of drug packaging quality to end users and pharmaceutical industry, as an indicator of the process of traceability and originality of drugs. Two surveys were conducted: one among the end users of drugs (252 patients) and the other among professionals working in seven pharmaceutical companies in Serbia. For most end users (82.5%) quality on the packaging of drugs was important, but only 41.8% of them thought that the appearance of the packaging could be an indicator of genuinity of drugs. The existence of the control marks (
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Mishra, Achyut, and Ganga Prasad Kharel. "Preservation and Quality Evaluation of Sisnu (Urtica plaviflora) by Making Gundruk like Fermented Product." Journal of Food Science and Technology Nepal 6 (June 29, 2013): 114–17. http://dx.doi.org/10.3126/jfstn.v6i0.8272.

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Sisnu (nettle buds) of variety Urtica plaviflora, an under explored herb of Himalayan region, was preserved by fermentation followed by drying process and quality was evaluated. Chemical analyses of fresh Sisnu was found to be 84.4% moisture, 3.64g crude protein, 4.15g ash, 1.66g fiber, 0.52g fat, 64.10mg potassium, 23.65mg calcium, 17.17mg Sodium and 32.12mg iron per 100g samples on dry basis. The protein and potassium contents were found approximately six times higher than other leafy vegetables. In fermented product, ash, calcium and potassium contents were decreased significantly (p<0.0
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Motovilov, K. Ya, S. K. Volonchuk, I. V. Naumenko, and A. I. Rezepin. "Development of the quality and safety control system in the technology of producing a protein-carbohydrate composite." Siberian Herald of Agricultural Science 50, no. 3 (2020): 36–48. http://dx.doi.org/10.26898/0370-8799-2020-3-4.

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The analysis of information sources of HACCP system used in the food industry for assessment of quality and microbiological safety of products is presented. The applicability of the principles of the HACCP system in the technology of producing a protein-carbohydrate composite as a feed product for cattle is analyzed. The research was conducted in 2018–2019 in Novosibirsk region. A brief description of the technology for producing a protein-carbohydrate composite in raw or dried form is given. The technology based on the HACCP principles comprised the control of raw materials, intermediate prod
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Gao, Dan, Chong Woon Cho, Cheong Taek Kim, Won Seok Jeong, and Jong Seong Kang. "Evaluation of the Antiwrinkle Activity of Enriched Isatidis Folium Extract and an HPLC–UV Method for the Quality Control of Its Cream Products." Plants 9, no. 11 (2020): 1586. http://dx.doi.org/10.3390/plants9111586.

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Currently, many extracts from natural sources are added to cosmetic products for reducing facial aging and wrinkles. This study investigated the antiwrinkle activity of enriched extract of Isatidis Folium used for a novel antiwrinkle cream product. The result demonstrated that this enriched extract has excellent antiwrinkle activity by significantly inhibiting mRNA expression of matrix metalloproteinase-1, matrix metalloproteinase-3, and pro-inflammatory cytokines IL-1β and upregulating the mRNA expression of IL-4 and procollagen. Additionally, to implement effective quality control of the ent
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Fleischer, Heidi, Vinh Quang Do, and Kerstin Thurow. "Online Measurement System in Reaction Monitoring for Determination of Structural and Elemental Composition Using Mass Spectrometry." SLAS TECHNOLOGY: Translating Life Sciences Innovation 24, no. 3 (2019): 330–41. http://dx.doi.org/10.1177/2472630318813838.

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The monitoring of chemical reactions is an important task in chemical engineering, especially in quality control, pharmaceutical and biological processes, or industrial production. The development of new reactions such as catalyst-based procedures requires detailed knowledge about process steps and reaction kinetics. For qualitative and quantitative analysis of reactants and resulting products, proprietary online measurement systems are used, which were designed for special applications. A mobile online reaction monitoring system was developed for a flexible coupling to different mass selectiv
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Kamel, Khaled, and Eman Kamel. "PLC Batch Process Control Design and Implementation Fundamentals." September 2020 2, no. 3 (2020): 155–61. http://dx.doi.org/10.36548/jei.2020.3.001.

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Batch process control is typically used for repeated chemical reaction tasks. It starts with a measured liquid material filling operations followed by a controlled reaction leading to the discharge or transport of processed quantities of material. The input materials is contained in vessel reactor and subjected to a sequence of processing activities over a recipe predefined duration of time. Batch systems are designed to measure, process, and discharge a varying volume of liquid from drums, tanks, reactors, or other large storage vessel using a programmable logic controller (PLC). These system
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Lazareva, E. G., Kh Kh Gilmanov, A. V. Bigaeva, I. Yu Mikhailova, V. K. Semipyatny, and R. R. Vafin. "DNA authentication technologies for product quality monitoring in the wine industry." Food systems 3, no. 4 (2021): 11–14. http://dx.doi.org/10.21323/2618-9771-2020-3-4-11-14.

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Identification of wine product authenticity is a topical question in theRussian Federation. A solution to this problem can be DNA authentication of wines, which is a technological process of product authenticity control using genetic identification of the main plant ingredient — wine grape varieties. This type of wine verification is carried out by analyzing residual amounts of Vitis vinifera L. nucleic acids extracted from cell debris of final products by molecular genetic methods. The aim of this work is the analysis of the existing methods for extraction of nucleic acids from grapes, wine r
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Kamboj, Anjoo, Ishtdeep Kaur, and Narinder Kaur. "Recent Advances in Standardization of Herbal Drugs." Current Traditional Medicine 6, no. 4 (2020): 278–99. http://dx.doi.org/10.2174/2215083805666190613141613.

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Background: Herbal drugs play a significant role to maintain the human healthiness and to treat the ailments since the dawn of civilization. Moreover, these plants have provided many lead compounds that culminated in modern medicine. A single herb is regarded as mini-combinatorial library of phytoconstituents hence the quality control of herbal drugs in an herbal formulation is not an easy task because a number of factors impact their pharmacological efficiency and consistent therapeutic effects. Hence, to provide consistent beneficial therapeutic effects, standardized herbal products of consi
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Chun, Myung-Hee, Ji Yeon Kim, Eun-Seok Park, and Du Hyung Choi. "Development of a Robust Control Strategy for Fixed-Dose Combination Bilayer Tablets with Integrated Quality by Design, Statistical, and Process Analytical Technology Approach." Pharmaceutics 13, no. 9 (2021): 1443. http://dx.doi.org/10.3390/pharmaceutics13091443.

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Control strategy and quality by design (QbD) are widely used to develop pharmaceutical products and improve drug quality; however, studies on fixed-dose combination (FDC) bilayer tablets are limited. In this study, the bilayer tablet consisted of high-dose metformin HCl in a sustained-release layer and low-dose dapagliflozin l-proline in an immediate-release layer. The formulation and process of each layer were optimized using the QbD approach. A d-optimal mixture design and response surface design were applied to optimize critical material attributes and critical process parameters, respectiv
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Michalski, Rajmund, Sebastian Szopa, Magdalena Jabłońska, and Aleksandra Łyko. "Application of Hyphenated Techniques in Speciation Analysis of Arsenic, Antimony, and Thallium." Scientific World Journal 2012 (2012): 1–17. http://dx.doi.org/10.1100/2012/902464.

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Due to the fact that metals and metalloids have a strong impact on the environment, the methods of their determination and speciation have received special attention in recent years. Arsenic, antimony, and thallium are important examples of such toxic elements. Their speciation is especially important in the environmental and biomedical fields because of their toxicity, bioavailability, and reactivity. Recently, speciation analytics has been playing a unique role in the studies of biogeochemical cycles of chemical compounds, determination of toxicity and ecotoxicity of selected elements, quali
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Kornyushko, V. F., O. M. Nikolaeva, A. V. Panov, R. R. Biglov, and A. S. Kuznetsov. "Quality management of the chemical-technological process for continuous synthesis of pharmaceutical substances of medicinal compounds in flow microreactors." Fine Chemical Technologies 16, no. 3 (2021): 252–66. http://dx.doi.org/10.32362/2410-6593-2021-16-3-252-266.

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Objectives. The introduction of digital tools for the development of medicines, intelligent management systems, and quality control is stipulated not only by modern requirements for the chemical and pharmaceutical industry but also by strict regulatory requirements for manufactured products. This principle ensures the release of a quality product on the first attempt. The aim of this study is to develop information support for the intelligent quality management system for the production of active pharmaceutical substances (APSs) for medicines using a fundamentally new technology: continuous sy
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Rosyadi, Susetyo Ilman, Eddy Afrianto, Achmad Rizal, and Rusky Intan Pratama. "ANALYSIS OF GOOD MANUFACTURING PRACTICE AT HOME INDUSTRY FOR CATFISH FLOSS IN PURWOSARI, KEDIRI REGENCY." Berkala Perikanan Terubuk 47, no. 2 (2019): 126. http://dx.doi.org/10.31258/terubuk.47.2.126-133.

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This study aims to study the application of Good Manufacturing Practice (GMP) at home industry for catfish floss in Purwosari, Kediri Regency. This research was conducted in May 2017, located in Purwosari Village Kandat Subdistrict Kediri Regency and Fisheries Processing Laboratory of Padjadjaran University. Laboratory testing was conducted at the Laboratory of Testing Services Faculty of Agricultural Industrial Technology Padjadjaran University and Laboratory of Control and Testing of Quality of Fishery Products of East Java. The method used is survey, by observing directly the flow of proces
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Battalov, A. F., R. T. Saetova, and Ya V. Denisova. "Improvement of organizational and methodological issues of analytical control of natural gas quality in Testing laboratory." Omsk Scientific Bulletin, no. 178 (2021): 29–33. http://dx.doi.org/10.25206/1813-8225-2021-178-29-33.

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The increased requirements for the quality of natural gas transported and used in industrial and domestic purposes have significantly increased the role of the analytical laboratory in the production process, since if the results of analyzes that determine the quality of products depend on the entire work of the gas transportation company as a whole, then the quality and reliability of the analysis results themselves are determined by the work of the testing laboratory. The basis of consumer confidence in the purchased products is ensured by the reliability of confirmation of the conformity of
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Stankov, Stanko. "A supervisory control system of a biodiesel production plant." Chemical Industry 72, no. 6 (2018): 315–28. http://dx.doi.org/10.2298/hemind180726024s.

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This paper describes a system for control and monitoring of plants for production of ecologically pure fuel biodiesel, which is obtained by transforming vegetable oils into fatty acid methyl esters by the reaction of transesterification. The automation provides synchronized operation of installed devices and equipment, protection and blockage of devices in the cases of irregularities, optimum energy consumption, elimination of subjective factor influences, increased efficiency of the plant and achievement of required product quality. It also enables prediction and diagnosis of faults, preventi
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