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Journal articles on the topic 'Chemicals effects'

Author: Grafiati

Published: 8 June 2024

Last updated: 31 July 2025

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1

Rybak, Leonard P. "Hearing: The Effects of Chemicals." Otolaryngology–Head and Neck Surgery 106, no. 6 (1992): 677–86. http://dx.doi.org/10.1177/019459989210600611.

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Recent studies of human beings exposed to environmental chemicals, as well as experimental animal studies, have identified a number of chemical agents that are commercial products, chemical intermediaries, waste products, or contaminants that are potentially ototoxic. The classes of compounds discussed in this review include organic solvents, asphyxiant gases, and heavy metals that are present in the environment as Industrial pollutants or byproducts. Both human and animal investigations are summarized in discussing the actions of these ototoxic compounds. The suggested gaps in our knowledge a

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2

Giesy, J. P., L. A. Feyk, P. D. Jones, Kurunthachalam Kannan, and T. Sanderson. "Review of the effects of endocrine-disrupting chemicals in birds." Pure and Applied Chemistry 75, no. 11-12 (2003): 2287–303. http://dx.doi.org/10.1351/pac200375112287.

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There have been several case studies of the impact of chemical contaminants on birds at the level of individuals or populations. While many of the chemicals involved in these incidents have been classified as endocrine-disrupting chemicals or endocrine active substances (EASs) the mechanisms by which these chemicals affect birds are not clearly or fully understood.

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3

Braun, Georg, Gunda Herberth, Martin Krauss, et al. "Neurotoxic mixture effects of chemicals extracted from blood of pregnant women." Science 386, no. 6719 (2024): 301–9. http://dx.doi.org/10.1126/science.adq0336.

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Human biomonitoring studies typically capture only a small and unknown fraction of the entire chemical universe. We combined chemical analysis with a high-throughput in vitro assay for neurotoxicity to capture complex mixtures of organic chemicals in blood. Plasma samples of 624 pregnant women from the German LiNA cohort were extracted with a nonselective extraction method for organic chemicals. 294 of >1000 target analytes were detected and quantified. Many of the detected chemicals as well as the whole extracts interfered with neurite development. Experimental testing of simulated complex

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4

Wheeler, David C., Salem Rustom, Matthew Carli, Todd P. Whitehead, Mary H. Ward, and Catherine Metayer. "Assessment of Grouped Weighted Quantile Sum Regression for Modeling Chemical Mixtures and Cancer Risk." International Journal of Environmental Research and Public Health 18, no. 2 (2021): 504. http://dx.doi.org/10.3390/ijerph18020504.

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Individuals are exposed to a large number of diverse environmental chemicals simultaneously and the evaluation of multiple chemical exposures is important for identifying cancer risk factors. The measurement of a large number of chemicals (the exposome) in epidemiologic studies is allowing for a more comprehensive assessment of cancer risk factors than was done in earlier studies that focused on only a few chemicals. Empirical evidence from epidemiologic studies shows that chemicals from different chemical classes have different magnitudes and directions of association with cancers. Given incr

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Wheeler, David C., Salem Rustom, Matthew Carli, Todd P. Whitehead, Mary H. Ward, and Catherine Metayer. "Assessment of Grouped Weighted Quantile Sum Regression for Modeling Chemical Mixtures and Cancer Risk." International Journal of Environmental Research and Public Health 18, no. 2 (2021): 504. http://dx.doi.org/10.3390/ijerph18020504.

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Individuals are exposed to a large number of diverse environmental chemicals simultaneously and the evaluation of multiple chemical exposures is important for identifying cancer risk factors. The measurement of a large number of chemicals (the exposome) in epidemiologic studies is allowing for a more comprehensive assessment of cancer risk factors than was done in earlier studies that focused on only a few chemicals. Empirical evidence from epidemiologic studies shows that chemicals from different chemical classes have different magnitudes and directions of association with cancers. Given incr

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6

Pollis, Rebecca E., Andrew L. Reid, and Lenly J. Weathers. "Effects of chemicals microorganisms." Water Environment Research 70, no. 4 (1998): 915–21. http://dx.doi.org/10.2175/106143098x134532.

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7

Rivera, Brianna N., Lindsay B. Wilson, Doo Nam Kim, et al. "A Comparative Multi-System Approach to Characterizing Bioactivity of Commonly Occurring Chemicals." International Journal of Environmental Research and Public Health 19, no. 7 (2022): 3829. http://dx.doi.org/10.3390/ijerph19073829.

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A 2019 retrospective study analyzed wristband personal samplers from fourteen different communities across three different continents for over 1530 organic chemicals. Investigators identified fourteen chemicals (G14) detected in over 50% of personal samplers. The G14 represent a group of chemicals that individuals are commonly exposed to, and are mainly associated with consumer products including plasticizers, fragrances, flame retardants, and pesticides. The high frequency of exposure to these chemicals raises questions of their potential adverse human health effects. Additionally, the possib

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8

Tomioka, Masahiro. "High-throughput assessment of the behavioral responses to toxic organic solvents in Caenorhabditis elegans." PLOS ONE 20, no. 4 (2025): e0311460. https://doi.org/10.1371/journal.pone.0311460.

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Novel chemical compounds are continuously being developed for use in various industries and daily life. Workers in these industries assess and avoid chemical hazards based on published information about chemical toxicities. However, avoiding the hazards associated with chemicals with unknown toxicity is difficult. Therefore, understanding the toxicities of chemicals in a high-throughput, multifaceted manner is essential. In this study, I developed a high-throughput method for assessing chemical toxicities through quantitative measurement of behavior in Caenorhabditis elegans. I determined the

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9

Liu, Tao, Lei Chen, and Xiaoyong Pan. "An Integrated Multi-Label Classifier with Chemical-Chemical Interactions for Prediction of Chemical Toxicity Effects." Combinatorial Chemistry & High Throughput Screening 21, no. 6 (2018): 403–10. http://dx.doi.org/10.2174/1386207321666180601075428.

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Aims and Objective: Chemical toxicity effect is one of the major reasons for declining candidate drugs. Detecting the toxicity effects of all chemicals can accelerate the procedures of drug discovery. However, it is time-consuming and expensive to identify the toxicity effects of a given chemical through traditional experiments. Designing quick, reliable and non-animal-involved computational methods is an alternative way. Method: In this study, a novel integrated multi-label classifier was proposed. First, based on five types of chemical-chemical interactions retrieved from STITCH, each of whi

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10

Czarnota, Jenna, David C. Wheeler, and Chris Gennings. "Evaluating Geographically Weighted Regression Models for Environmental Chemical Risk Analysis." Cancer Informatics 14s2 (January 2015): CIN.S17296. http://dx.doi.org/10.4137/cin.s17296.

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In the evaluation of cancer risk related to environmental chemical exposures, the effect of many correlated chemicals on disease is often of interest. The relationship between correlated environmental chemicals and health effects is not always constant across a study area, as exposure levels may change spatially due to various environmental factors. Geographically weighted regression (GWR) has been proposed to model spatially varying effects. However, concerns about collinearity effects, including regression coefficient sign reversal (ie, reversal paradox), may limit the applicability of GWR f

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11

Boxall, Alistair, Anthony Hardy, Sabine Beulke, et al. "Impacts of climate change on indirect human exposure to pathogens and chemicals from agriculture." Ciência & Saúde Coletiva 15, no. 3 (2010): 743–56. http://dx.doi.org/10.1590/s1413-81232010000300017.

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Climate change is likely to affect the nature of pathogens/ chemicals in the environment and their fate and transport. We assess the implications of climate change for changes in human exposures to pathogens/chemicals in agricultural systems in the UK and discuss the effects on health impacts, using expert input and literature on climate change; health effects from exposure to pathogens/chemicals arising from agriculture; inputs of chemicals/pathogens to agricultural systems; and human exposure pathways for pathogens/chemicals in agricultural systems. We established the evidence base for healt

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12

Huang, Zehao, Na Li, Kaifeng Rao, Cuiting Liu, Zijian Wang, and Mei Ma. "In vitro Cytotoxicity and Genotoxicity Analysis of Ten Tannery Chemicals Using SOS/umu Tests and High-content In vitro Micronucleus Tests." Combinatorial Chemistry & High Throughput Screening 21, no. 4 (2018): 262–70. http://dx.doi.org/10.2174/1386207321666180330120248.

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Background: More than 2,000 chemicals have been used in the tannery industry. Although some tannery chemicals have been reported to have harmful effects on both human health and the environment, only a few have been subjected to genotoxicity and cytotoxicity evaluations. Objective: This study focused on cytotoxicity and genotoxicity of ten tannery chemicals widely used in China. Materials and Methods: DNA-damaging effects were measured using the SOS/umu test with Salmonella typhimurium TA1535/pSK1002. Chromosome-damaging and cytotoxic effects were determined with the high-content in vitro Micr

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13

Jain, Neha. "Terrorism at Rise with the Chemicals Insight: Use of Chemical Warfare Agents an Issue of Global Concern." Journal of Forensic Chemistry and Toxicology 9, no. 1 (2023): 47–51. http://dx.doi.org/10.21088/jfct.2454.9363.9123.3.

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Crime has led to a worldwide increase with a main weapon of offence including not only a physical object but show the incidences of involvement of chemicals also. Chemical warfare agents are one such example commonly employed by large group of people, mainly violent criminals who not only wants to create a terror or threat in the world but to cause war scale destruction. There are numerous of incidents reported from past showing the involvement of hazardous chemicals for committing crimes. Chemical Warfare Agents (CWA) are synthetic chemicals used in the warfare as weapons, which are highly to

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14

Slunge, Daniel, and Francisco Alpizar. "Market-Based Instruments for Managing Hazardous Chemicals: A Review of the Literature and Future Research Agenda." Sustainability 11, no. 16 (2019): 4344. http://dx.doi.org/10.3390/su11164344.

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We take stock of the lessons learned from using market-based instruments in chemicals management and discuss the potential for increased use of risk-based taxation in the management of pesticides and other hazardous chemicals. Many chemical substances cause significant diffuse emissions when emitted over wide areas at individually low concentrations. These emissions are typically very difficult and costly to control. The targeted chemical may exist in many products as well as in a wide variety of end uses. However, the current regulatory instruments used are primarily bans or quantitative rest

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15

Jarema, Kimberly A., Deborah L. Hunter, Bridgett N. Hill, et al. "Developmental Neurotoxicity and Behavioral Screening in Larval Zebrafish with a Comparison to Other Published Results." Toxics 10, no. 5 (2022): 256. http://dx.doi.org/10.3390/toxics10050256.

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With the abundance of chemicals in the environment that could potentially cause neurodevelopmental deficits, there is a need for rapid testing and chemical screening assays. This study evaluated the developmental toxicity and behavioral effects of 61 chemicals in zebrafish (Danio rerio) larvae using a behavioral Light/Dark assay. Larvae (n = 16–24 per concentration) were exposed to each chemical (0.0001–120 μM) during development and locomotor activity was assessed. Approximately half of the chemicals (n = 30) did not show any gross developmental toxicity (i.e., mortality, dysmorphology or non

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16

Kurita, Hisaka, Kazuki Ohuchi, and Masatoshi Inden. "Effects of Environmental Non-Essential Toxic Heavy Metals on Epigenetics During Development." Toxics 13, no. 3 (2025): 167. https://doi.org/10.3390/toxics13030167.

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We are exposed to a variety of environmental chemicals in our daily lives. It is possible that the effects of this daily chemical exposure could accumulate in the organism in some form and influence health and disease development. The exposure effects extend throughout the human lifetime, not only after birth, but also during the embryonic period. Epigenetics is an important target for the molecular mechanisms of daily environmental chemical effects. Epigenetics is a mechanism of gene transcription regulation that does not involve changes in DNA sequence. The Developmental Origins of Health an

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17

Xu, Hao, Jian Zhao, Yang Jing, Jingcong Xie, Ning Zhang, and Jianchun Jiang. "Effects of apple and pear wood vinegar components on Pleurotus ostreatus mycelium growth." BioResources 15, no. 2 (2020): 2961–70. http://dx.doi.org/10.15376/biores.15.2.2961-2970.

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In order to facilitate the application of wood vinegar in the mushroom industry, a framework was developed to reveal the individual and interactive effects of chemical groups in wood vinegars on Pleurotus ostreatus mycelium growth. By a series of refining and separating methods, the crude wood vinegar samples were processed and separated into six subgroups with distinctive component concentrations in each. Adding the wood vinegar subgroups into the culturing medium resulted in differences in mycelium growth. Analysis of variance was performed on the differences to evaluate the effects of seven

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18

Welch, Samuel A., Taylor Lane, Alizée O. S. Desrousseaux, et al. "ECORISK2050: An Innovative Training Network for predicting the effects of global change on the emission, fate, effects, and risks of chemicals in aquatic ecosystems." Open Research Europe 1 (May 16, 2022): 154. http://dx.doi.org/10.12688/openreseurope.14283.2.

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By 2050, the global population is predicted to reach nine billion, with almost three quarters living in cities. The road to 2050 will be marked by changes in land use, climate, and the management of water and food across the world. These global changes (GCs) will likely affect the emissions, transport, and fate of chemicals, and thus the exposure of the natural environment to chemicals. ECORISK2050 is a Marie Skłodowska-Curie Innovative Training Network that brings together an interdisciplinary consortium of academic, industry and governmental partners to deliver a new generation of scientists

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19

Welch, Samuel A., Taylor Lane, Alizée O. S. Desrousseaux, et al. "ECORISK2050: An Innovative Training Network for predicting the effects of global change on the emission, fate, effects, and risks of chemicals in aquatic ecosystems." Open Research Europe 1 (December 20, 2021): 154. http://dx.doi.org/10.12688/openreseurope.14283.1.

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By 2050, the global population is predicted to reach nine billion, with almost three quarters living in cities. The road to 2050 will be marked by changes in land use, climate, and the management of water and food across the world. These global changes (GCs) will likely affect the emissions, transport, and fate of chemicals, and thus the exposure of the natural environment to chemicals. ECORISK2050 is a Marie Skłodowska-Curie Innovative Training Network that brings together an interdisciplinary consortium of academic, industry and governmental partners to deliver a new generation of scientists

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20

Bynum, Karina, Jared Lynn, and Lenly J. Weathers. "Effects of Chemicals on Microorganisms." Water Environment Research 72, no. 6 (2001): 1679–724. http://dx.doi.org/10.2175/106143000x144259.

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21

Clesceri, Lenore S. "Effects of chemicals on microorganisms." Water Environment Research 73, no. 6 (2001): 1573–80. http://dx.doi.org/10.2175/106143001x144500.

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22

Reish, Donald J., Philip S. Oshida, Alan J. Mearns, Thomas C. Ginn, and Michael Buchanan. "Effects of Chemicals on Microorganisms." Water Environment Research 73, no. 6 (2001): 1581–657. http://dx.doi.org/10.2175/106143001x144519.

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23

Clesceri, Lenore S. "Effects of Chemicals on Microorganisms." Water Environment Research 74, no. 6 (2002): 1496–506. http://dx.doi.org/10.2175/106143002x140738.

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24

Clesceri, Lenore S. "Effects of Chemicals on Microorganisms." Water Environment Research 75, no. 6 (2003): 1755–66. http://dx.doi.org/10.2175/106143003x145354.

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25

Clesceri, Lenore S. "Effects of Chemicals on Microorganisms." Water Environment Research 76, no. 6 (2004): 2386–98. http://dx.doi.org/10.2175/106143004x145858.

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26

Clesceri, Lenore S. "Effects of Chemicals on Microorganisms." Water Environment Research 77, no. 6 (2005): 2719–32. http://dx.doi.org/10.2175/106143005x54650.

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27

Clesceri, Lenore S. "Effects of Chemicals on Microorganisms." Water Environment Research 78, no. 10 (2006): 2028–32. http://dx.doi.org/10.2175/106143006x119495.

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28

Taylor, Aubrey E. "Cardiovascular Effects of Environmental Chemicals." Otolaryngology–Head and Neck Surgery 114, no. 2 (1996): 209–11. http://dx.doi.org/10.1016/s0194-59989670167-5.

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This article presents recent data on several environmental toxins: lead, carbon disulfide, asbestos, arsenic, ozone, cadmium, vinyl chloride, fiuorocarbons, freon, and pesticides. These environmental toxins produce both hypertension and cardiac arrhythmias in most studies, and they are not necessarily related to primary lung disease and secondary heart disease. The possible mechanisms that could cause the cardiovascular diseases include (1) damage to the endothelial barrier in the vascular system, (2) activation of leukocytes and platelets, (3) initiation of plaque formation, (4) stimulation o

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29

Levine, Audrey D., and Jeffrey M. Black. "Effects of chemicals on microorganisms." Water Environment Research 68, no. 4 (1996): 768–76. http://dx.doi.org/10.2175/106143096x135632.

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30

Levine, Audrey D., and Jarrod D. Case. "Effects of chemicals on microorganisms." Water Environment Research 69, no. 4 (1997): 874–77. http://dx.doi.org/10.2175/106143097x135082.

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31

Beitler, Gloria V. "Unrecognized Health Effects of Chemicals." AAOHN Journal 58, no. 5 (2010): 207–11. http://dx.doi.org/10.3928/08910162-20100416-02.

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32

Greenberg, Michael R. "Health Effects of Environmental Chemicals." Journal of Planning Literature 1, no. 1 (1985): 1–13. http://dx.doi.org/10.1177/088541228500100102.

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"Polemical" is the best word to describe the voluminous literature about the health effects of environmental chemicals. The literature includes both lengthy scientific treatises that few read and brief emotional pleas heard by many; books that are one-sided representations and misdefinitions of important single words; and vitriolic attacks on subspecialities and people. Unfortunately, the literature does not include sufficient information to allow us to determine the risk posed by the majority of chemicals in the human environment. In light of this state of knowledge, planners must work with o

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33

Beitler, Gloria V. "Unrecognized Health Effects of Chemicals." AAOHN Journal 58, no. 5 (2010): 207–13. http://dx.doi.org/10.1177/216507991005800505.

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34

TAYLOR, A. "Cardiovascular effects of environmental chemicals." Otolaryngology - Head and Neck Surgery 114, no. 2 (1996): 209–11. http://dx.doi.org/10.1016/s0194-5998(96)70167-5.

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35

Vargová, M., D. Zeljenková, and M. Gajdová. "Estrogenic effects of environmental chemicals." Toxicology Letters 78 (August 1995): 82. http://dx.doi.org/10.1016/0378-4274(95)94971-i.

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36

Vargová, M. "Estrogenic Effects of Environmental Chemicals." Toxicology Letters 78 (August 1995): 82. http://dx.doi.org/10.1016/03784-2749(59)4972j-.

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37

Levine, Audrey D., and Manaskorn Rachakornkij. "Effects of chemicals on microorganisms." Water Environment Research 66, no. 4 (1994): 611–23. http://dx.doi.org/10.1002/j.1554-7531.1994.tb00126.x.

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38

Zieburtz, William B. "Effects of Chemicals on Microorganisms." Water Environment Research 75, no. 7 (2003): 1950–64. http://dx.doi.org/10.1002/j.1554-7531.2003.tb00215.x.

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39

Saganuwan, Saganuwan Alhaji. "Chemistry and Effects of Brainstem Acting Drugs." Central Nervous System Agents in Medicinal Chemistry 19, no. 3 (2019): 180–86. http://dx.doi.org/10.2174/1871524919666190620164355.

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Background: Brain is the most sensitive organ, whereas brainstem is the most important part of Central Nervous System (CNS). It connects the brain and the spinal cord. However, a myriad of drugs and chemicals affects CNS with severe resultant effects on the brainstem. Methods: In view of this, a number of literature were assessed for information on the most sensitive part of brain, drugs and chemicals that act on the brainstem and clinical benefit and risk assessment of such drugs and chemicals. Results: Findings have shown that brainstem regulates heartbeat, respiration and because it connect

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40

Khan, Yousaf. "Chemicals that Disrupt the Endocrine System and their Effects on Human Health." Open Access Journal of Endocrinology 7, no. 1 (2023): 1–4. http://dx.doi.org/10.23880/oaje-16000179.

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Endocrine glands are the important glands of human that performs certain functions and has specific characteristics. The main function of these glands is that they regulate the whole system by producing hormones which they produce indigenously and pours them directly in the blood for a targeted action and all of their functions are involuntary. They are specifically ductless glands and their course of action is regulated by a pea size Pituitary gland or sometimes referred as the Master Gland. Until now, very less has been known about these glands that their actions or functions are being inter

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41

Walker, John D., David Knaebel, Kelly Mayo, Jay Tunkel, and D. Anthony Gray. "Use of QSARs to Promote More Cost-Effective Use of Chemical Monitoring Resources. 1. Screening Industrial Chemicals and Pesticides, Direct Food Additives, Indirect Food Additives and Pharmaceuticals for Biodegradation, Bioconcentration and Aquatic Toxicity Potential." Water Quality Research Journal 39, no. 1 (2004): 35–39. http://dx.doi.org/10.2166/wqrj.2004.006.

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Abstract Monitoring studies are expensive to conduct. To promote more cost-effective use of chemical monitoring resources, quantitative structure activity relationships (QSARs) are proposed as methods to identify chemicals that could be found in, and cause adverse effects to, organisms in water, sediment and soil from the Great Lakes basin. QSARs were used to predict the biodegradation, bioconcentration and aquatic toxicity potential of 2697 industrial chemicals and pesticides, 1146 direct food additives, 967 indirect food additives and 282 pharmaceuticals that could be released to the Great L

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Faroon, Obaid M., Sam Keith, Dennis Jones, and Christopher De Rosa. "Carcinogenic effects of polychlorinated biphenyls." Toxicology and Industrial Health 17, no. 2 (2001): 41–62. http://dx.doi.org/10.1191/0748233701th098oa.

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As part of its mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) prepares toxicological profiles on hazardous chemicals found at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) National Priorities List (NPL) sites that have the greatest public health impact. These profiles comprehensively summarize toxicological and environmental information. This article constitutes the release of an important section of the Toxicological profile for polychlorinated biphenyls [ATSDR. 2000: Toxicological profile for polychlorinated biphenyls. Atlanta, GA: US D

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Zhang, Yinbing. "Research on Health Effects of Environmental Chemicals Based on Structure and Gene Association Analysis." Materials Physics and Chemistry 1, no. 4 (2019): 1. http://dx.doi.org/10.18282/mpc.v1i4.791.

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<p>China is a major producer and consumer of chemicals. The production and use of chemicals play a role in the development of the entire national economy. Therefore, effective chemical management has a huge impact on the development of the national economy. At present, chemical management guidelines have achieved a lot in chemical operations, but there are still many shortcomings. Relevant institutions should further improve the standard system, strengthen the coordination of subjective institutions, the supervision and management, establish information standards, complete information sh

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Manunayaka, G., and S. Ganesamoorthi. "Knowledge of Vegetable Growers on the Effects of Agricultural Chemicals." International Journal of Environment and Climate Change 13, no. 10 (2023): 784–90. http://dx.doi.org/10.9734/ijecc/2023/v13i102716.

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The present study was conducted in Kolar district of Karnataka state during 2018-19 to understand the knowledge level of vegetable growers on the effects of agricultural chemicals. The data was collected from 120 vegetable growing farmers in Kolar and Malur talukas by applying simple random sampling technique and pretested interview schedule. Results revealed that more than forty per cent of the vegetable growers (42.50 %) possessed medium level of knowledge on the effects of agricultural chemicals, more than three fourth of the vegetable growers. (77.50 %) knew that taking bath using soap imm

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Rogan, Walter J., and N. Beth Ragan. "Evidence of Effects of Environmental Chemicals on the Endocrine System in Children." Pediatrics 112, Supplement_1 (2003): 247–52. http://dx.doi.org/10.1542/peds.112.s1.247.

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Pollutant chemicals that are widespread in the environment can affect endocrine signaling, as evidenced in laboratory experiments and in wildlife with relatively high exposures. Although humans are commonly exposed to such pollutant chemicals, the exposures are generally low, and clear effects on endocrine function from such exposures have been difficult to demonstrate. Several instances in which there are data from humans on exposure to the chemical agent and the endocrine outcome are reviewed, including age at weaning, age at puberty, and sex ratio at birth, and the strength of the evidence

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46

Park, Juyoung, Handule Lee, Dal-Woong Choi, and Kwangsik Park. "The mixture effect of propyl paraben and bisphenol A on the uterotrophic response in the ovariectomized rats after oral administration." Environmental Analysis Health and Toxicology 38, no. 1 (2023): e2023006. http://dx.doi.org/10.5620/eaht.2023005.

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Recent studies reported bisphenol A (BPA) and propyl paraben (PrP) are found in human urine, blood, and breast milk samples as well as in food, packaging, socks, and clothes. This means that the two chemicals co-exist in consumer products, and humans are exposed simultaneously to the mixture chemicals. However, the studies on the mixture effects of the two chemicals on human health are not enough. This study was designed to elucidate the effects of orally administered PrP, BPA, and their mixture effects on the uterotrophic response using ovariectomized rats. In addition, the correlation betwee

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47

Huang, Xiu-Ling, Jun Wang, Xiao-Hui Qu, Chong-Xing Huang, and Kit Yam. "A release model considering chemical loss from a double-layer material into food." Thermal Science 24, no. 4 (2020): 2419–26. http://dx.doi.org/10.2298/tsci2004419h.

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The migration of chemicals from packaging materials into food is predictable by various mathematical models. However, the loss of chemicals makes the predictions more complicated. In this article, a mathematical model considering chemical instability is developed to quantify the release of chemicals through double-layer packaging films based on Fick's diffusion and first order reaction. At the same time, two different loading modes are considered in the loss function. The release model is solved numerically to elucidate the effects of diffusivity value, distribution of chemical and mass transf

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48

Vuong, Ann M., Kimberly Yolton, Joseph M. Braun, Bruce P. Lanphear, and Aimin Chen. "Chemical mixtures and neurobehavior: a review of epidemiologic findings and future directions." Reviews on Environmental Health 35, no. 3 (2020): 245–56. http://dx.doi.org/10.1515/reveh-2020-0010.

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AbstractBackgroundEpidemiological studies have historically focused on single toxicants, or toxic chemicals, and neurodevelopment, even though the interactions of chemicals and nutrients may result in additive, synergistic, antagonistic, or potentiating effects on neurological endpoints. Investigating the impact of environmentally-relevant chemical mixtures, including heavy metals and endocrine disrupting chemicals (EDCs), is more reflective of human exposures and may result in more refined environmental policies to protect the public.ObjectiveIn this review, we provide a summary of epidemiolo

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Grandjean, P., S. H. Sandoe, and Renate D. Kimbrough. "Non-specificity of Clinical Signs and Symptoms Caused by Environmental Chemicals." Human & Experimental Toxicology 10, no. 3 (1991): 167–73. http://dx.doi.org/10.1177/096032719101000303.

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1 A review of the scientific literature revealed that 220 environmental chemicals had caused documented systemic toxicity in humans. This number is relatively small compared to the large number of industrial chemicals in the environment. 2 A total of 149 of these chemicals were verified as neurotoxins, thus emphasizing the sensitivity of this target organ. Despite the exclusion of chemicals that cause airway irritation only, 99 chemicals caused adverse effects on the respiratory system. Toxicity to the liver, kidneys and blood forming organs was less frequent. 3 Most of the individual clinical

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Escher, Beate I., Heather M. Stapleton, and Emma L. Schymanski. "Tracking complex mixtures of chemicals in our changing environment." Science 367, no. 6476 (2020): 388–92. http://dx.doi.org/10.1126/science.aay6636.

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Chemicals have improved our quality of life, but the resulting environmental pollution has the potential to cause detrimental effects on humans and the environment. People and biota are chronically exposed to thousands of chemicals from various environmental sources through multiple pathways. Environmental chemists and toxicologists have moved beyond detecting and quantifying single chemicals to characterizing complex mixtures of chemicals in indoor and outdoor environments and biological matrices. We highlight analytical and bioanalytical approaches to isolating, characterizing, and tracking

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