Academic literature on the topic 'CHEMIOTERAPIA E MICROBIOLOGIA'

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Journal articles on the topic "CHEMIOTERAPIA E MICROBIOLOGIA"

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Getinger-Panek, Agnieszka, and Ilona Bednarek. "Grzyby Endofityczne w Roli Potencjalnych Producentów Związków Przeciwnowotworowych." Postępy Mikrobiologii - Advancements of Microbiology 61, no. 2 (2022): 63–72. http://dx.doi.org/10.2478/am-2022-0006.

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Streszczenie Główną rolę w chemioterapii raka od ponad 50 lat, stanowią leki pochodzące w większości ze źródeł naturalnych. Przeciwko licznym dolegliwościom od stuleci rośliny służyły jako źródło związków bioaktywnych. Jednak to nie same rośliny, a mikroorganizmy z nimi związane oferują materiał i produkty o wysokim potencjale terapeutycznym. Endofity to organizmy, które kolonizują wewnętrzne tkanki roślin bez wywoływania objawów chorobowych. Stanowią endosymbiotyczną grupę drobnoustrojów, będących źródłem nowatorskich produktów naturalnych do wykorzystania we współczesnym przemyśle, rolnictwi
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Getinger-Panek, Agnieszka, and Ilona Bednarek. "GRZYBY ENDOFITYCZNE W ROLI POTENCJALNYCH PRODUCENTÓW ZWIĄZKÓW PRZECIWNOWOTWOROWYCH." Postępy Mikrobiologii - Advancements of Microbiology, June 9, 2022. http://dx.doi.org/10.2478/am-2022.0006.

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Streszczenie Główną rolę w chemioterapii raka od ponad 50 lat, stanowią leki pochodzące w większości ze źródeł naturalnych. Przeciwko licznym dolegliwościom od stuleci rośliny służyły jako źródło związków bioaktywnych. Jednak to nie same rośliny, a mikroorganizmy z nimi związane oferują materiał i produkty o wysokim potencjale terapeutycznym. Endofity to organizmy, które kolonizują wewnętrzne tkanki roślin bez wywoływania objawów chorobowych. Stanowią endosymbiotyczną grupę drobnoustrojów, będących źródłem nowatorskich produktów naturalnych do wykorzystania we współczesnym przemyśle, rolnictwi
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Dissertations / Theses on the topic "CHEMIOTERAPIA E MICROBIOLOGIA"

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GOMBAC, FRANCESCA. "RUOLO DEGLI INTEGRONI NELLA TRASMISSIONE DI ANTIBIOTICO- RESISTENZE IN ACINETOBACTER." Doctoral thesis, Università degli studi di Trieste, 2003. http://thesis2.sba.units.it/store/handle/item/12662.

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GIONECHETTI, FABRIZIA. "L' ANTIBIOTICO RESISTENZA NELL' AMBIENTE MONITORAGGIO IN BATTERI ISOLATI DA AVIFAUNA." Doctoral thesis, Università degli studi di Trieste, 2003. http://thesis2.sba.units.it/store/handle/item/12664.

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2001/2002<br>Development of antibiotic resistance in bacteria is mainly due to the presence of resistance genes and to the selective pressure exerted by antibiotic use. Resistance can result from spontaneous mutations or acquisition of genes coding for a resistance mechanism. Antibacterial agents are used in agricultural techniques, in human and animai therapy and prevention of bacteria infections, and are added continuously to animai feeds to promote growth. As a result of exposure to antibiotics, the level of antibiotic resistance of bacteria belonging to the normal intestina! flora of human
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Cvorovic, Jovana. "The role of anthocyanidins in the treatment of colorectal cancer." Doctoral thesis, Università degli studi di Trieste, 2009. http://hdl.handle.net/10077/3041.

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2007/2008<br>Colorectal cancer is among four most common malignancies and the second leading cause of cancer death in the western world. Although the standard treatment regimens have improved the prognosis, resistance to cytotoxic chemotherapy is still a common problem in these patients and a major obstacle to effective treatment of disseminated neoplasms. The subject of this study was to evaluate a possible role of anthocyanidins, natural products belonging to the group of flavonoids, in the treatment of colorectal cancer. Primary (CACO-2) and metastatic human colorectal carcinoma cell lines
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Maestro, Alessandra. "Trasporto di flavonoidi in cellule endoteliali: ruolo della bilitranslocasi e delle proteine ABC." Doctoral thesis, Università degli studi di Trieste, 2008. http://hdl.handle.net/10077/2569.

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2006/2007<br>I flavonoidi sono metaboliti secondari presenti in numerose piante commestibili che rappresentano una parte integrante dell’alimentazione umana. Numerosi studi epidemiologici hanno dimostrato che una dieta ricca di flavonoidi può avere un ruolo rilevante nella prevenzione di diverse patologie, come alcune neoplasie e le malattie cardiovascolari. L’endotelio vascolare svolge un ruolo fondamentale nel mantenimento dell’omeostasi vascolare e alterazioni a questo livello, in particolare se croniche, possono causare l’avvio di lesioni arteriosclerotiche. I flavonoidi esplicano le loro
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Zanette, Caterina. "Caratterizzazione dei meccanismi neuroprotettivi della guanosina e dei ligandi dei recettori sigma." Doctoral thesis, Università degli studi di Trieste, 2009. http://hdl.handle.net/10077/3044.

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2007/2008<br>Rispetto al ruolo svolto da nucleosidi e nucleotidi adeninici come neurotrasmettitori/neuromodulatori, quello delle purine a base guaninica è ancora largamente sconosciuto. In questo studio, è stato valutato l’effetto della guanosina sulle cellule SH-SY5Y, derivate da un neuroblastoma umano. In questa linea cellulare, la guanosina aumenta la proliferazione di cellule sottoposte a stress da deprivazione da siero per 24, 48 e 72h (MTT test), effetto che sembra coinvolgere la via delle MAPK e quella di PI3K, ma non quella dell’AMP ciclico (AMPc). Utilizzando [3H]Adenosina e [3H]Gua
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TUVERI, ROSSANA. "Identification & characterization of natural and synthetic compounds as new anticancer agents." Doctoral thesis, Università degli Studi di Cagliari, 2016. http://hdl.handle.net/11584/266770.

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This thesis collects the work I have done during the three-year PhD Course. During my first year I have started a path that has allowed me to acquire different techniques devoted to set up and maintain primary cell cultures and cancer derived cell lines as well as to evaluate the cytotoxicity of potential novel synthetic inhibitors of human cancer cells. Part of the second and all the third year was spent at the University of Cape Town, South Africa, in the laboratory of prof. Ariel Katz under the supervision of proff. Roger Hunter and Catherine H. Kaschula investigating the anticancer a
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PINNA, ELISABETTA. "Studies on the synergic activity of a three-drug cocktail active against cisplatin-resistant human leukemia and carcinoma cells." Doctoral thesis, Università degli Studi di Cagliari, 2016. http://hdl.handle.net/11584/266701.

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Objectives. At the light of properties and limits of cisplatin (CDDP) as an anticancer agent, and in view of the potential clinical relevance of the synergic effect of CDDP with the Cu(II)-phen complexes previously reported against T-leukemia cells (Pivetta et al.,Talanta, 2013), my research project was aimed at (1) extending the studies of CDDP-Cu(II)-phen combinations as such, as well as with the addition of a third drug component; (2) determining the potential degree of selectivity of the most synergic drug combinations. Methods. Most studies were focused on the most potent Cu(II)Phen comp
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