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Journal articles on the topic 'Chemlox'

Author: Grafiati

Published: 4 June 2021

Last updated: 4 February 2022

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1

Ulrich, Hannes, Dorit Grundmann, and Dirk Sander. "ChemSex." Ärztliche Psychotherapie 15, no. 2 (2020): 101–7. http://dx.doi.org/10.21706/aep-15-2-101.

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2

Barbier, Jacques. "Chemsex." Insistance 13, no. 1 (2017): 189. http://dx.doi.org/10.3917/insi.013.0189.

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3

Kumar, Sushil. "CHEMCON 2009." Indian Chemical Engineer 52, no. 1 (2010): 51–56. http://dx.doi.org/10.1080/00194501003759803.

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4

Glyde, Tania. "Chemsex exposed." Lancet 386, no. 10010 (2015): 2243–44. http://dx.doi.org/10.1016/s0140-6736(15)01111-3.

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5

Butenschön, Holger. "CHEMKON volljährig!" CHEMKON 21, no. 4 (2014): 161. http://dx.doi.org/10.1002/ckon.201410235.

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6

Chen, Zi, Chun Wang, and Weiwei Feng. "Comparison of 12-Month Treatment Costs for Patients with Advanced Phase Chronic Myeloid Leukemia (CML) in China: Imatinib (IM) vs. Chemotherapy (Chemo) Plus Interferon-(IFN) in Accelerated Phase (AP) CML and IM vs. Chemo in Blast Crisis (BC) CML." Blood 110, no. 11 (2007): 5169. http://dx.doi.org/10.1182/blood.v110.11.5169.5169.

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Abstract Background: IM, an oral molecular targeted therapy, has demonstrated impressive efficacy in treating advanced CML. In China, IM has been approved to treat all phases of CML. However, it was not considered for reimbursement at national level. Chemos such as Homoharringtonine combined with cytarabine (HA) or Theprucine in combination with cytarabine (TA) have been used and reimbursed to treat advanced CML patients. The objective of this study was to conduct a total cost of treatment analysis comparing IM with chemo (HA or TA) in combination with IFN in AP and IM vs. chemo in BC CML in China. Methods: Total cost of treatment contained drug cost, office visits, lab tests, hospitalizations, and cost of managing adverse events (AEs) and supportive care. The cost of managing AEs included the use of G-CSF, anti-infective medications, and blood transfusions. Treatment protocols for AP and BC CML from tier 3 hospitals in China were used to estimate the costs associated with treatment. Drug prices were based on the listed retail price in China. Dosages for IM and IFN were based on the approved product labels in China. Results: AP patients received on average 3 courses of chemo in the hospital during a year and were treated with interferon-while off the chemo. BC patients received one course chemo every two months. As shown in the table, the 12-month cost of treatment for an AP patient treated with IM was RMB119,850 vs. RMB153,900 with chemo plus IFN. The corresponding numbers for a BC patient were RMB133,450 with IM vs. RMB18,5400 with chemo. Hospitalizations and costs of managing adverse events and supportive care were the key drivers of the savings for IM. The health care costs savings related to taking IM outweigh the drug cost difference between IM and chemo plus IFN in AP or IM and chemo in BC. Conclusion: AP CML patients treated with IM incurred over RMB30,000 less health care costs in 1-year than those treated with chemo plus IFN. The savings were even more in BC: the 1-year cost of treatment with IM was over RMB50,000 lower than that with chemo. The cost of chemo used in this analysis was based on the 1st line chemo used in China. If patients failed the 1st line chemo, more expensive 2nd line chemos were usually used. Therefore, the total cost of treatment with chemo in advanced CML could be even more if 2nd line chemos were considered in this analysis. Providing advanced CML patients access to IM will not only improve clinical outcomes but also reduce the overall economic burden to the Chinese health care system. Total 12-month Cost of Treatment for Advanced Phase CML Patients (unit: RMB) AP BC Imatinib Chemo+IFN Imatinib Chemo *Other = Chemo + IFN in AP; Other = Chemo in BC Drug cost 114,750 75,000 114,750 42,000 Office visits 600 8,100 600 9,000 Lab tests 600 3,600 600 included in above office visits Hospitalizations 1,400 18,000 6,000 36,000 Cost of managing AEs and supportive care 2,500 49,200 11,500 98,400 Total cost of treatment 119,850 153,900 133,450 185,400 Difference in total cost of treatment (Imatinib - Other*) − 34,050 − 51,950

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7

Redondo Domínguez, David, Luis Picazo, María Luisa Docavo Barrenechea-Moxo, and Juan González del Castillo. "Chemsex: ¿estamos preparados?" Adicciones 30, no. 2 (2018): 158. http://dx.doi.org/10.20882/adicciones.1062.

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8

Bader, Hans-Joachim. "25 Jahre CHEMKON." CHEMKON 25, no. 5 (2018): 175. http://dx.doi.org/10.1002/ckon.201800067.

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9

Dolengevich-Segal, Helen, Beatriz Rodríguez-salgado, Jesús Bellesteros-López, and Rocío Molina-Prado. "Chemsex. Un fenómeno emergente." Adicciones 29, no. 3 (2017): 207. http://dx.doi.org/10.20882/adicciones.894.

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10

Bianchi, Andrew. "Chemsex and the city." Lancet Infectious Diseases 16, no. 4 (2016): 419. http://dx.doi.org/10.1016/s1473-3099(16)00135-3.

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11

Srivastava, V. K. "Presidential Address: CHEMCON 2010." Indian Chemical Engineer 53, no. 1 (2011): 35–38. http://dx.doi.org/10.1080/00194506.2011.659542.

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12

Ganeshan, S. "Presidential Address: CHEMCON 2008." Indian Chemical Engineer 51, no. 1 (2009): 51–56. http://dx.doi.org/10.1080/00194500903122559.

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13

Adam, Horst. "ChemLab. Spielen im Labor?" Chemie in unserer Zeit 31, no. 4 (1997): 204. http://dx.doi.org/10.1002/ciuz.19970310413.

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14

Kreher, Richard P. "Leser fragen - CHEMKON antwortet." CHEMKON 6, no. 4 (1999): 202–3. http://dx.doi.org/10.1002/ckon.19990060411.

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15

Jansen, Walter. "Editorial: Zehn Jahre CHEMKON …" CHEMKON 10, no. 4 (2003): 169. http://dx.doi.org/10.1002/ckon.200390052.

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16

Montforts, Franz-Peter. "Contents: Chemkon 1/2004." CHEMKON 11, no. 1 (2004): 3. http://dx.doi.org/10.1002/ckon.200490000.

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17

Gertzen, Marcus, Moritz Strasburger, Jan Geiger, et al. "Chemsex." Der Nervenarzt, April 14, 2021. http://dx.doi.org/10.1007/s00115-021-01116-x.

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18

"ACS ChemWorx." Chemical & Engineering News Archive 91, no. 43 (2013): 32. http://dx.doi.org/10.1021/cen-09143-ad12.

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19

"ACS ChemWorx." Chemical & Engineering News Archive 92, no. 23 (2014): 18. http://dx.doi.org/10.1021/cen-09223-ad07.

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20

"ACS ChemWorx." Chemical & Engineering News Archive 92, no. 26 (2014): ibc. http://dx.doi.org/10.1021/cen-09226-ad08.

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21

"ACS ChemWorx." Chemical & Engineering News Archive 92, no. 27 (2014): obc. http://dx.doi.org/10.1021/cen-09227-ad17.

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22

"ACS ChemWorx." Chemical & Engineering News Archive 93, no. 29 (2015): ibc. http://dx.doi.org/10.1021/cen-09329-ad09.

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23

"ACS ChemWorx." Chemical & Engineering News Archive 91, no. 13 (2013): 37. http://dx.doi.org/10.1021/cen-09113-ad17.

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24

"ACS ChemWorx." Chemical & Engineering News Archive 91, no. 14 (2013): 25. http://dx.doi.org/10.1021/cen-09114-ad06.

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25

"ACS ChemWorx." Chemical & Engineering News Archive 91, no. 15 (2013): 44. http://dx.doi.org/10.1021/cen-09115-ad10.

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26

"ACS ChemWorx." Chemical & Engineering News Archive 91, no. 17 (2013): 9. http://dx.doi.org/10.1021/cen-09117-ad03.

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27

"Sheffield Chemdex." Choice Reviews Online 45, no. 03 (2007): 45–1206. http://dx.doi.org/10.5860/choice.45-1206.

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28

"Lubrizol acquires Chemron." Focus on Surfactants 2002, no. 6 (2002): 7. http://dx.doi.org/10.1016/s1351-4210(02)00651-0.

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29

Slagstad, Ketil. "Chemsex på norsk." Tidsskrift for Den norske legeforening, 2019. http://dx.doi.org/10.4045/tidsskr.18.0875.

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30

"Sherry R. Chemler." C&EN Global Enterprise 95, no. 2 (2017): 35–37. http://dx.doi.org/10.1021/cen-09502-awards004.

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31

"Aktuelle Informationen: CHEMKON." CHEMKON, April 16, 2020. http://dx.doi.org/10.1002/ckon.202000021.

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32

"Aktuelle Informationen: CHEMKON." CHEMKON, November 17, 2020. http://dx.doi.org/10.1002/ckon.202000059.

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33

"HIV Prevention During Chemsex." Case Medical Research, May 21, 2019. http://dx.doi.org/10.31525/ct1-nct03956758.

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34

"Inhalt: Chemkon 2/2005." CHEMKON 12, no. 2 (2005): 51. http://dx.doi.org/10.1002/ckon.200590011.

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35

"Titelbild: Chemkon 4/2005." CHEMKON 12, no. 4 (2005): n/a. http://dx.doi.org/10.1002/ckon.200590040.

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36

"Inhalt: Chemkon 1/2006." CHEMKON 13, no. 1 (2006): 3. http://dx.doi.org/10.1002/ckon.200690000.

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37

"Titelbild (CHEMKON 5/2013)." CHEMKON 20, no. 5 (2013). http://dx.doi.org/10.1002/ckon.201390009.

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38

"Inhaltsverzeichnis: CHEMKON 5/2019." CHEMKON 26, no. 5 (2019): 175. http://dx.doi.org/10.1002/ckon.201980511.

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39

Soria, María Luisa. "Aspectos toxicológicos del chemsex." Revista Española de Medicina Legal, July 2020. http://dx.doi.org/10.1016/j.reml.2020.05.013.

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40

"Personalia: Chemkon 1/2003." CHEMKON 10, no. 1 (2002): 55–56. http://dx.doi.org/10.1002/ckon.200390012.

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41

"Leserforum: Chemkon 2/2004." CHEMKON 11, no. 2 (2004): 92–95. http://dx.doi.org/10.1002/ckon.200490013.

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42

"Inhaltsverzeichnis: CHEMKON 1/2014." CHEMKON 21, no. 1 (2014): 3. http://dx.doi.org/10.1002/ckon.201490001.

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43

"Inhalt: Chemkon 3/2004." CHEMKON 11, no. 3 (2004): 111. http://dx.doi.org/10.1002/ckon.200490015.

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44

"Inhalt: CHEMKON 1/2007." CHEMKON 14, no. 1 (2007): NA. http://dx.doi.org/10.1002/ckon.200790011.

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45

"Inhalt: CHEMKON 3/2007." CHEMKON 14, no. 3 (2007). http://dx.doi.org/10.1002/ckon.200790039.

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46

"Inhaltsverzeichnis: CHEMKON 2/2018." CHEMKON 25, no. 2 (2018): 55. http://dx.doi.org/10.1002/ckon.201880211.

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47

"Titelbild: (CHEMKON 3/2018)." CHEMKON 25, no. 3 (2018): 85. http://dx.doi.org/10.1002/ckon.201880301.

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48

"Inhaltsverzeichnis: CHEMKON 3/2018." CHEMKON 25, no. 3 (2018): 87. http://dx.doi.org/10.1002/ckon.201880311.

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49

"Schüleraufgabe: CHEMKON 5/2019." CHEMKON 26, no. 5 (2019): 215–16. http://dx.doi.org/10.1002/ckon.201980571.

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50

"Titelbild: CHEMKON 1/2009." CHEMKON 16, no. 1 (2009): n/a. http://dx.doi.org/10.1002/ckon.200990008.

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