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Journal articles on the topic 'Chi jing zhai'

Author: Grafiati

Published: 27 July 2024

Last updated: 31 July 2025

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1

Zhao, Wen-Yu, Zhi-Lin Luan, Cheng-Peng Sun, et al. "Metabolites isolated from the human intestinal fungus Penicillium oxalicum SL2 and their agonistic effects on PXR and FXR." Phytochemistry 193 (January 31, 2022): 1–11. https://doi.org/10.1016/j.phytochem.2021.112974.

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Zhao, Wen-Yu, Luan, Zhi-Lin, Sun, Cheng-Peng, Zhang, Bao-Jing, Jin, Ling-Ling, Deng, Sa, Zhang, Hou-Li, Yu, Zhen-Long, Wang, Chao, Ma, Xiao-Chi (2022): Metabolites isolated from the human intestinal fungus Penicillium oxalicum SL2 and their agonistic effects on PXR and FXR. Phytochemistry (112974) 193: 1-11, DOI: 10.1016/j.phytochem.2021.112974, URL: http://dx.doi.org/10.1016/j.phytochem.2021.112974

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Wang, Wen-Jing, Lei Wang, Zhong Liu, et al. "Antiviral benzofurans from Eupatorium chinense." Phytochemistry 122 (February 29, 2016): 238–45. https://doi.org/10.1016/j.phytochem.2015.11.013.

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Wang, Wen-Jing, Wang, Lei, Liu, Zhong, Jiang, Ren-Wang, Liu, Zhi-Wen, Li, Man-Mei, Zhang, Qing-Wen, Dai, Yi, Li, Yao-Lan, Zhang, Xiao-Qi, Ye, Wen-Cai (2016): Antiviral benzofurans from Eupatorium chinense. Phytochemistry 122: 238-245, DOI: 10.1016/j.phytochem.2015.11.013, URL: http://dx.doi.org/10.1016/j.phytochem.2015.11.013

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Zhu, Chaodong, Arong Luo, Ming Bai, et al. "A joint call for actions to advance taxonomy in China." Zoological Systematics 47, no. 3 (2022): 188–97. https://doi.org/10.11865/zs.2022302.

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Zhu, Chaodong, Luo, Arong, Bai, Ming, Orr, Michael C., Hou, Zhonge, Ge, Siqin, Chen, Jun, Hu, Yibo, Zhou, Xuming, Qiao, Gexia, Kong, Hongzhi, Lu, Limin, Jin, Xiaohua, Cai, Lei, Wei, Xinli, Zhao, Ruilin, Miao, Wei, Wang, Qingfeng, Sha, Zhongli, Lin, Qiang, Qu, Meng, Jiang, Jianping, Li, Jiatang, Che, Jing, Jiang, Xuelong, Chen, Xiaoyong, Gao, Lianming, Ren, Zongxin, Xiang, Chunlei, Luo, Shixiao, Wu, Donghui, Liu, Dong, Peng, Yanqiong, Su, Tao, Cai, Chenyang, Zhu, Tianqi, Cai, Wanzhi, Liu, Xingyue, Li, Hu, Xue, Huaijun, Ye, Zhen, Chen, Xuexin, Tang, Pu, Wei, Shujun, Pang, Hong, Xie, Qiang, Zhang

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Zhao, Wen-Yu, Jing Yi, Yi-Bo Chang, Cheng-Peng Sun, and Xiao-Chi Ma. "Recent studies on terpenoids in Aspergillus fungi: Chemical diversity, biosynthesis, and bioactivity." Phytochemistry 193 (January 31, 2022): 1–25. https://doi.org/10.1016/j.phytochem.2021.113011.

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Zhao, Wen-Yu, Yi, Jing, Chang, Yi-Bo, Sun, Cheng-Peng, Ma, Xiao-Chi (2022): Recent studies on terpenoids in Aspergillus fungi: Chemical diversity, biosynthesis, and bioactivity. Phytochemistry (113011) 193: 1-25, DOI: 10.1016/j.phytochem.2021.113011, URL: http://dx.doi.org/10.1016/j.phytochem.2021.113011

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Chai, Jing, Chen-Qi Lu, Mu-Rong Yi, et al. "Discovery of a wild, genetically pure Chinese giant salamander creates new conservation opportunities." Zoological research 43, no. 3 (2022): 469–80. https://doi.org/10.24272/j.issn.2095-8137.2022.101.

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Chai, Jing, Lu, Chen-Qi, Yi, Mu-Rong, Dai, Nian-Hua, Weng, Xiao-Dong, Di, Ming-Xiao, Peng, Yong, Tang, Yong, Shan, Qing-Hua, Wang, Kai, Liu, Huan-Zhang, Zhao, Hai-Peng, Jin, Jie-Qiong, Cao, Ru-Jun, Lu, Ping, Luo, Lai-Chun, Murphy, Robert W, Zhang, Ya-Ping, Che, Jing (2022): Discovery of a wild, genetically pure Chinese giant salamander creates new conservation opportunities. Zoological research 43 (3): 469-480, DOI: 10.24272/j.issn.2095-8137.2022.101, URL: http://dx.doi.org/10.24272/j.issn.2095-8137.2022.101

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Wagan, Tufail Ahmed, Yueping He, Wanlun Cai, Jing Zhao, and Hongxia Hua. "Fumigant and contact toxicity and oviposition deterrent effects of plant essential oils on Bemisia tabaci (Hemiptera: Aleyrodidae)." Florida Entomologist 99, no. 4 (2016): 673–77. https://doi.org/10.1653/024.099.0414.

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Wagan, Tufail Ahmed, He, Yueping, Cai, Wanlun, Zhao, Jing, Hua, Hongxia (2016): Fumigant and contact toxicity and oviposition deterrent effects of plant essential oils on Bemisia tabaci (Hemiptera: Aleyrodidae). Florida Entomologist 99 (4): 673-677, DOI: 10.1653/024.099.0414, URL: http://www.bioone.org/doi/10.1653/024.099.0414

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Cai, Hong-Xia, Jing Che, Jun-Feng Pang, Er-Mi Zhao, and Ya-Ping Zhang. "Paraphyly of Chinese Amolops (Anura, Ranidae) and phylogenetic position of the rare Chinese frog, Amolops tormotus." Zootaxa 1531, no. 1 (2007): 49–55. https://doi.org/10.11646/zootaxa.1531.1.4.

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Cai, Hong-Xia, Che, Jing, Pang, Jun-Feng, Zhao, Er-Mi, Zhang, Ya-Ping (2007): Paraphyly of Chinese Amolops (Anura, Ranidae) and phylogenetic position of the rare Chinese frog, Amolops tormotus. Zootaxa 1531 (1): 49-55, DOI: 10.11646/zootaxa.1531.1.4, URL: https://biotaxa.org/Zootaxa/article/view/zootaxa.1531.1.4

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Ushiroyama, Takahisa, Atsushi Ikeda, Kou Sakuma, and Minoru Ueki. "Chai-Hu-Gui-Zhi-Gan-Jiang-Tang Regulates Plasma Interleukin-6 and Soluble Interleukin-6 Receptor Concentrations and Improves Depressed Mood in Climacteric Women with Insomnia." American Journal of Chinese Medicine 33, no. 05 (2005): 703–11. http://dx.doi.org/10.1142/s0192415x05003338.

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This study was performed to compare the effects of Chai-hu-gui-zhi-gan-jiang-tang (Saiko-keishi-kankyo-to), an herbal medicine, in improving depressed mood and on plasma interleukin-6 (IL-6) and soluble interleukin-6 receptor (sIL-6R) concentrations with those of anti-depressants in peri- and post-menopausal women. Ninety patients complaining of menopausal symptoms including insomnia who were diagnosed with mood disorder based on DSM-IV were recruited and separated into two groups (Chai-hu-gui-zhi-gan-jiang-tang group was selected on the basis of SHO for 42 cases, while anti-depressants were u

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Cai, Lei, Shuai Peng, Jing Tian, et al. "Aspidistra austroyunnanensis (Asparagaceae), a new species from southern Yunnan, China." Phytotaxa 356, no. 3 (2018): 233–37. https://doi.org/10.11646/phytotaxa.356.3.5.

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Cai, Lei, Peng, Shuai, Tian, Jing, Dao, Zhi-Ling, Wei, Neng, Hu, Guang-Wan, Wang, Qing-Feng (2018): Aspidistra austroyunnanensis (Asparagaceae), a new species from southern Yunnan, China. Phytotaxa 356 (3): 233-237, DOI: 10.11646/phytotaxa.356.3.5, URL: http://dx.doi.org/10.11646/phytotaxa.356.3.5

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Deng, Lei, Jing-Xin Yao, Hai-Feng Liu, et al. "First report of Blastocystis in giant pandas, red pandas, and various bird species in Sichuan province, southwestern China." International Journal for Parasitology: Parasites and Wildlife 9 (August 31, 2019): 298–304. https://doi.org/10.1016/j.ijppaw.2019.06.007.

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Deng, Lei, Yao, Jing-Xin, Liu, Hai-Feng, Zhou, Zi-Yao, Chai, Yi-Jun, Wang, Wu-You, Zhong, Zhi-Jun, Deng, Jun-Liang, Ren, Zhi-Hua, Fu, Hua-Lin, Yan, Xia, Yue, Chan-Juan, Peng, Guang-Neng (2019): First report of Blastocystis in giant pandas, red pandas, and various bird species in Sichuan province, southwestern China. International Journal for Parasitology: Parasites and Wildlife 9: 298-304, DOI: 10.1016/j.ijppaw.2019.06.007, URL: http://dx.doi.org/10.1016/j.ijppaw.2019.06.007

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조성천. "The Translation and Annotation of Ten Pieces of Chi Du(尺牘) in Wang Fu-zhi's ≪Jiang Zhai Wen Ji≫". JOURNAL OF CHINESE STUDIES ll, № 46 (2014): 451–67. http://dx.doi.org/10.26585/chlab.2014..46.017.

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Wang, Mei-Hui. "Xiaolin: Un'esplorazione su barzellette e umorismo nella cultura cinese antica." Traduction et Langues 23, no. 2 (2024): 209–32. http://dx.doi.org/10.52919/translang.v23i2.1003.

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Xiaolin: An Exploration of Jokes and Humor in Ancient Chinese Culture This article is based on the study of the book "Xiaolin" (The Forest of Laughter) by Handan Chun 邯鄲淳 (ca.132-ca.221) of the Cao Wei 曹魏 period in the Eastern Han Dynasty 東漢 (25-220).The first book dedicated to jokes in ancient China. The realistic and satirical folk stories produced against the backdrop of the times, reflected the interest in life, humor and the educational sense of the literati, lower-class and common peopleof that period (Wang, 1981; Huang, 1999). Focusing on the only 29 jokes left in the book, the extracts

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Wang, Zengyuan, Mengjun Jiang, Afsar Khan, et al. "Epigynumgenane-type pregnane glycosides from Epigynum cochinchinensis and their immunosuppressive activity." Phytochemistry 168 (December 31, 2019): 1–8. https://doi.org/10.1016/j.phytochem.2019.112127.

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Wang, Zengyuan, Jiang, Mengjun, Khan, Afsar, Cai, Shengbao, Li, Xiaonian, Liu, Junqiu, Kai, Guoyin, Zhao, Tianrui, Cheng, Guiguang, Cao, Jianxin (2019): Epigynumgenane-type pregnane glycosides from Epigynum cochinchinensis and their immunosuppressive activity. Phytochemistry 168: 1-8, DOI: 10.1016/j.phytochem.2019.112127, URL: http://dx.doi.org/10.1016/j.phytochem.2019.112127

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Jiang, Xuan-Kong, Hui-Ming Chen, and Zhi-Cai Xie. "Description of two new species of the genus Glyphiulus Gervais, 1847 (Diplopoda: Spirostreptida: Cambalopsidae) from southern China." Zootaxa 5141, no. 4 (2022): 358–72. https://doi.org/10.11646/zootaxa.5141.4.4.

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Jiang, Xuan-Kong, Chen, Hui-Ming, Xie, Zhi-Cai (2022): Description of two new species of the genus Glyphiulus Gervais, 1847 (Diplopoda: Spirostreptida: Cambalopsidae) from southern China. Zootaxa 5141 (4): 358-372, DOI: 10.11646/zootaxa.5141.4.4

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Jiang, Xuan-Kong, Derek A. Hennen, Hui-Ming Chen, and Zhi-Cai Xie. "First description of the male of Glyphiulus formosus (Pocock, 1895) (Diplopoda Spirostreptida: Cambalopsidae) from China." Zootaxa 4861, no. 2 (2020): 281–89. https://doi.org/10.11646/zootaxa.4861.2.8.

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Jiang, Xuan-Kong, Hennen, Derek A., Chen, Hui-Ming, Xie, Zhi-Cai (2020): First description of the male of Glyphiulus formosus (Pocock, 1895) (Diplopoda Spirostreptida: Cambalopsidae) from China. Zootaxa 4861 (2): 281-289, DOI: 10.11646/zootaxa.4861.2.8

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Liang, Zhi-Qun, Hui Chai, Shuai Jiang, Zheng-Kun Ye, and Nian-Kai Zeng. "The genus Xanthoconium (Boletaceae, Boletales) in tropical China." Phytotaxa 295, no. 3 (2017): 246–54. https://doi.org/10.11646/phytotaxa.295.3.5.

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Liang, Zhi-Qun, Chai, Hui, Jiang, Shuai, Ye, Zheng-Kun, Zeng, Nian-Kai (2017): The genus Xanthoconium (Boletaceae, Boletales) in tropical China. Phytotaxa 295 (3): 246-254, DOI: 10.11646/phytotaxa.295.3.5, URL: http://dx.doi.org/10.11646/phytotaxa.295.3.5

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Jiang, Xuan-Kong, Zu-Xu Zhang, Hui-Ming Chen, and Zhi-Cai Xie. "Description of Hypocambala zizhongi sp. nov. and the new combination, Glyphiulus polytrichus (Golovatch et al., 2011) comb. nov., based on morphological and molecular data (Spirostreptida: Cambalidea: Cambalopsidae)." Zootaxa 4903, no. 3 (2021): 405–18. https://doi.org/10.11646/zootaxa.4903.3.6.

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Jiang, Xuan-Kong, Zhang, Zu-Xu, Chen, Hui-Ming, Xie, Zhi-Cai (2021): Description of Hypocambala zizhongi sp. nov. and the new combination, Glyphiulus polytrichus (Golovatch et al., 2011) comb. nov., based on morphological and molecular data (Spirostreptida: Cambalidea: Cambalopsidae). Zootaxa 4903 (3): 405-418, DOI: 10.11646/zootaxa.4903.3.6

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Cao, GuiPing, Ling Xu, YuLong Wang, FeiXiang Ma, Hua Yuan, and RongFang Tang. "Investigating mechanism of Jiang-zhi-dai-pao-cha for treatment of hyperlipidemia by network pharmacology." Drug Combination Therapy 4, no. 1 (2022): 4. http://dx.doi.org/10.53388/dct2022004.

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Yesiller, Nazli, and Kenneth R. Bell. "Editorial: 2024 Reviewer Thank Yous." Geotechnical Testing Journal 47, no. 6 (2024): 1179–80. http://dx.doi.org/10.1520/gtj20249998.

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Abstract The individuals listed here provided reviews for the papers in Volume 47 of the Geotechnical Testing Journal (GTJ). The Co-Editors of GTJ, Dr. Nazli Yesiller and Dr. Kenneth Bell, express their appreciation to the reviewers for their diligence, assiduity, and professionalism in conducting the reviews. Detailed input and constructive criticism from the reviewers allow for maintaining the high quality of the journal. The time and efforts of the reviewers are acknowledged and greatly appreciated. Asif Ahmed Pavan Akula Ceren Aydin Jean Benoit Tejo Bheemasetti Riya Bhowmik Nripojyoti Bisw

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Zhang, Qingyuan, Shusen Wang, Nanlin Li, et al. "Abstract PO1-27-01: Comparing the Efficacy and Safety of TQB2440 versus the Reference Pertuzumab for the Treatment of HER2-Positive Early or Locally Advanced Breast Cancer: A Multicenter, Randomized, Double-Blind, Parallel-Controlled Phase 3 Trial." Cancer Research 84, no. 9_Supplement (2024): PO1–27–01—PO1–27–01. http://dx.doi.org/10.1158/1538-7445.sabcs23-po1-27-01.

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Abstract Background: Pertuzumab is a recombinant humanized monoclonal antibody targeting the extracellular dimerization domain II of HER2. On September 30, 2013, the FDA have granted accelerated approval of a pertuzumab regimen for neoadjuvant treatment of patients (pts) with high-risk, HER2-positive early stage breast cancer. TQB2440 is a pertuzumab (Perjeta®, Roche) biosimilar. This study aimed to compare the efficacy and safety of TQB2440 and the reference pertuzumab combined with trastuzumab and docetaxel in pts with HER2-positive early or locally advanced breast cancer. Methods: In this m

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ITOH, Tadanobu, Shigeo MURAI, Hiroko SAITO, Noboru OHKUBO, Hiroshi SAITO, and Seisuke MICHIJIRI. "The Effect of Saiko-ka-ryukotsu-borei-to(Chai-Hu-Jia-Long-Gu-Mu-Li-Tang) and Saiko-keishi kankyo-to(Chai-Hu-Gui-Zhi-Gan-Jiang-Tang) on the Monoamines and their Metabolism in Mouse Brains." Kampo Medicine 47, no. 4 (1997): 593–601. http://dx.doi.org/10.3937/kampomed.47.593.

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SUWANNAPOOM, CHATMONGKON, ZHI-YONG YUAN, JIN-MIN CHEN, et al. "Erratum: CHATMONGKON SUWANNAPOOM, ZHI-YONG YUAN, JIN-MIN CHEN, MIAN HOU, HAI-PENG ZHAO, LI-JUN WANG, TRUONG SON NGUYEN, TRUONG Q. NGUYEN, ROBERT W. MURPHY, JAQUELINE SULLIVAN, DAVID S. MCLEOD & JING CHE (2016) Taxonomic revision of the Chinese Limnonectes (Anura, Dicroglossidae) with the description of a new species from China and Myanmar. Zootaxa, 4093: 181–200." Zootaxa 4137, no. 4 (2016): 599. http://dx.doi.org/10.11646/zootaxa.4137.4.13.

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23

Takano, Fumihide, Yasuyuki Ohta, Tomoaki Tanaka, et al. "Oral Administration of Ren-Shen-Yang-Rong-Tang ‘Ninjin’yoeito’ Protects against Hematotoxicity and Induces Immature Erythroid Progenitor Cells in 5-Fluorouracil-Induced Anemia." Evidence-Based Complementary and Alternative Medicine 6, no. 2 (2009): 247–56. http://dx.doi.org/10.1093/ecam/nem080.

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The purpose of this study was to investigate the efficacy of four different Japanese and Chinese herbal prescriptions, Ren-Shen-Yang-Rong-Tang (Ninjin’yoeito, NYT), Chai-Hu-Gui-Zhi-Gan-Jiang-Tang (Saikokeishikankyoto, SKKT), Si-Jun-Zi-Tang (Shikunshito, SKT) and Si-Wu-Tang (Shimotsuto, SMT), which are traditionally used for anemia and fatigue, against hematotoxicity in mice treated with 5-fluorouracil (5-FU). NYT 1–100 mg kg–1day–1injected orally for 7 consecutive days before and after 5-FU injection significantly suppressed reductions in red blood cell, white blood cell and platelet counts in

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Artiushin, S., J. F. Timoney, J. Nally, and A. Verma. "Host-Inducible Immunogenic Sphingomyelinase-Like Protein, Lk73.5, of Leptospira interrogans." Infection and Immunity 72, no. 2 (2004): 742–49. http://dx.doi.org/10.1128/iai.72.2.742-749.2004.

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ABSTRACT Leptospira interrogans causes a variety of clinical syndromes in animals and humans. Although much information has accumulated on the importance of leptospiral lipopolysaccharide in protective antibody responses, relatively little is known about proteins that participate in immune responses. Identification of those proteins induced only in the host is particularly difficult. Using a novel double-antibody screen designed to identify clones in a gene library of L. interrogans serovar Pomona expressing host-inducible proteins, we have characterized a gene (lk75.3) encoding a sphingomyeli

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Li, Bingsi, Jing Su, Guangliang Zhang, et al. "Abstract 5116: Analytical performance of ELSA-seq, a blood-based test for early detection of multiple cancers." Cancer Research 82, no. 12_Supplement (2022): 5116. http://dx.doi.org/10.1158/1538-7445.am2022-5116.

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Abstract Introduction: Detection of cancer is its early stages can potentially improve therapeutic effectiveness. Previously, we demonstrated that ELSA-seq, a machine-learning-aided methylation profiling test, can detect and locate multiple cancers with high accuracy in plasma samples. Here, we evaluated the analytical performance of a refined test version of ELSA-seq, including analytical sensitivity, specificity, repeatability/reproducibility, and robustness. Methods: The classification algorithm and cut-offs for the ELSA-seq test were established in the THUNDER study (NCT04820868). Here, we

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Han, Fudong. "(Electrodeposition Division Early Career Investigator Award) Understanding and Controlling Electrodeposition of Li in Solid Electrolytes." ECS Meeting Abstracts MA2022-02, no. 24 (2022): 1007. http://dx.doi.org/10.1149/ma2022-02241007mtgabs.

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The successful integration of Li metal anode with solid electrolytes seems to be a must for a high-energy-density solid-state battery. However, Li dendrites tend to form in solid electrolytes during Li plating. The formation of dendrites has been observed in solid electrolytes with various crystal structures from glass, glass-ceramic, poly-crystalline to single-crystalline materials, but the mechanism of such an unexpected dendrite growth remains elusive. In this presentation, I will introduce our understandings of lithium dendrite formation in solid electrolytes based on operando neutron dept

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Gou, Hongyan, Shang Guo, Xiaohong Wang, et al. "Abstract LB132: C8orf76 promotes colorectal tumorigenesis by promoting an immunosuppressive microenvironment and is a therapeutic target for boosting anti-PD-1 efficacy." Cancer Research 85, no. 8_Supplement_2 (2025): LB132. https://doi.org/10.1158/1538-7445.am2025-lb132.

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Abstract Immune checkpoint blockade (ICB) therapy demonstrated limited efficacy in colorectal cancer (CRC), and identification of intrinsic factors modulating immune suppression in CRC is an unmet need. Here, we revealed that Chromosome 8 open reading frame 76 (C8orf76) drives immunosuppression and is a molecular target to boost ICB therapy in CRC. C8orf76 is upregulated in primary CRCs compared to adjacent normal tissues in 2 independent CRC cohorts and its expression predicts poor patient survival. Intestine-specific C8orf76 knockin in mice exacerbated AOM/DSS-induced CRC, accompanied by inc

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Razak, Nurul Nadia, Moh Yasin, Zahriladha Zakaria, Anas A. Latiff, and Sulaiman Wadi Harun. "Q-switched fiber laser with tungsten disulfide saturable absorber prepared by drop casting method." Photonics Letters of Poland 9, no. 3 (2017): 103. http://dx.doi.org/10.4302/plp.v9i3.752.

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We experimentally demonstrate a passively Q-switched erbium-doped fiber laser (EDFL) operation by using a saturable absorber (SA) based on tungsten disulfide (WS2). By depositing WS2 thin film layer at the end of optical fiber ferrule, we fabricated a SA device. The SA is incorporated into an Erbium-doped fiber laser (EDFL) cavity to generate a Q-switching pulses train operating at 1559.8 nm. As a result, stable passively Q-switched EDFL pulses with maximum output pulse energy of 123.2 nJ, repetition rate of 104.1 kHz, and pulse width of 9.61 us are achieved when the input pump power is 142.1

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Zhou, Long-Xia, An-Ning Yang, Jiu-Kai Chen та ін. "Corrigendum to “Zhou LX, Yang AN, Chen JK, Zhao L, Wang YH, Liu XM, Cai X, Zhang MH, Jiang YD, Cao J. Endoplasmic reticulum oxidoreductin 1α mediates homocysteine-induced hepatocyte endoplasmic reticulum stress” [Shijie Huaren Xiaohua Zazhi 2014; 22(34): 5228-5234]". World Chinese Journal of Digestology 27, № 16 (2019): 1041–42. http://dx.doi.org/10.11569/wcjd.v27.i16.1041.

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Cai, Wenhan, Miao Jing, Jiaxin Wen, Yajun Gu, Xiaochen Zhao, and Zhiqiang Xue. "Abstract 6110: Immune cell infiltrative characteristics reveals the superior efficacy of neoadjuvant immunochemotherapy versus chemotherapy alone in a real-world cohort of resectable non-small cell lung cancer." Cancer Research 82, no. 12_Supplement (2022): 6110. http://dx.doi.org/10.1158/1538-7445.am2022-6110.

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Abstract We aimed to analyze the efficacy of neoadjuvant immunochemotherapy versus chemotherapy alone in the real-world settings, and to further explore tumor immune microenviroment (TIME), as well as its influence on response of neoadjuvant therapy in patients with NSCLC. Fifty-three patients with neoadjuvant therapy (immunochemotherapy, n=22; chemotherapy alone, n=31), resectable stage I~III, age≥18 years, and ECOG performance status 0-1 were recruited in the study. Fluorescent multiplex immunohistochemistry was performed by the automated quantitative pathology imaging system with tumor samp

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Guo, Shiying, Lingyu Song, Xin Qin, et al. "Abstract 5199: B7-H3 & PD-L1 double-humanized BALB/c mouse: a novel animal model for preclinical studies of human B7-H3 antibodies or bispecific antibodies." Cancer Research 83, no. 7_Supplement (2023): 5199. http://dx.doi.org/10.1158/1538-7445.am2023-5199.

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Abstract Immune checkpoint molecule B7-H3, also known as CD276, is a member of the B7-CD28 family of immunomodulatory proteins. It is a type I membrane protein with sequence similarities to the extracellular domain of programmed death-ligand 1 (PD-L1). B7-H3 is highly expressed in most human cancers, but has limited distribution in normal tissues, remaining elusive of its receptor. Due to its promising safety as a dominant tumor target, various strategies have been developed to modulate the effect of B7-H3 via monoclonal antibodies, bispecific antibodies, ADC, or CAR-T. To study the effect of

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Li, Yu-Wei, Ding Ma, Xiang-Rong Wu, et al. "Abstract PS09-09: Multiomics profiling and molecular classification refine precision treatment strategies for HER2-positive breast cancer." Cancer Research 84, no. 9_Supplement (2024): PS09–09—PS09–09. http://dx.doi.org/10.1158/1538-7445.sabcs23-ps09-09.

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Abstract Background: Anti-HER2 targeted therapy has achieved a series of breakthroughs. However, the current treatment strategy regarding HER2-positive breast cancer remains indiscriminate and lacks specificity, which limits the further improvement of overall treatment response and may lead to overtreatment and extra cost for some patients. Our study aims to reveal the molecular heterogeneity of HER2-positive breast cancer to guide a more precise treatment. Patients and methods: We selected HER2-positive breast cancer patients treated at Fudan University Shanghai Cancer Center between 2013 and

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La Monaca, Andrea, Valentina Pava, Anna Welburn, et al. "BiVO₄ Photoanodes for Photo-Assisted Electrochemical Water Splitting." ECS Meeting Abstracts MA2025-01, no. 39 (2025): 2090. https://doi.org/10.1149/ma2025-01392090mtgabs.

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Among all the hydrogen generation technologies, electrolysis driven by clean energy is currently the sustainable technology of choice but is relatively costly hampering its wide adoption.1 Meanwhile, solar energy is ubiquitous and abundant; hence it could be the best candidate to drive the water splitting reaction. Photoelectrochemical (PEC) water splitting is currently gaining a lot of interest in the research field, however several challenges still need to be addressed to feasibly produce hydrogen on the large scale. The main limitation is of kinetic nature and stems from the oxidation of wa

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Wang, Nan, Zhuonan Wang та Hongyu Zheng. "Round Heaven and Square Earth, the Unity of the Pagoda and Statues—A Study on the Geometric Proportions of the Architectural Space, Statues, and Murals in Ying Xian Fogong Si Shijia Ta 應縣佛宮寺釋迦塔 (Sakyamuni Pagoda of Fogong Temple in Ying County)". Religions 15, № 7 (2024): 802. http://dx.doi.org/10.3390/rel15070802.

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In Ying Xian Fogong Si Shijia Ta 應縣佛宮寺釋迦塔 (Sakyamuni Pagoda of Fogong Temple in Ying County), Shanxi, there are statues set on each floor, and 26 exist in total, with six murals painted on the first floor. The pagoda was designed as a vertically rising Buddhist temple, and the interior space of each floor was customized for the statues. Based on previous research and through surveying and mapping of the architecture and statuary (including the murals on the first floor) combined with geometric design analysis, this paper proposes the following: First, there exists a clear geometric proportion

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Guo, Jing, Lijia Liu, Xiangyong Liu, et al. "Abstract 6511: BPI-520105, a highly potent, CNS-penetrant 4th generation EGFR inhibitor overcoming major EGFR resistance mutations in NSCLC." Cancer Research 84, no. 6_Supplement (2024): 6511. http://dx.doi.org/10.1158/1538-7445.am2024-6511.

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Abstract EGFR activating mutations are prevalent in 10-50% of NSCLC patients. The most common EGFR mutations, L858R (L) and Del19 (D), initially respond to first-, second-, or third-generation (1G, 2G and 3G) EGFR-TKIs. However, on-target resistance, primarily by T790M (T) and C797X(C), inevitably emerges post-treatment and leads to disease progression. Different treatment sequence give rise to different complex mutations. In patients resistant to the 3G TKI osimertinib, double mutations L858R/C797X or Del19/C797X (LC or DC) were observed at a frequency of up to 12% after first-line osimertini

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Zhao, Hui, Yujie Chang, Zhiyuan Jiang, Zhiyu Wang, and Shunyi Ruan. "Abstract CT543: 18F-FDG PET/CT detects potentially malignant bone metastases in patients with suspected lesions: A prospective clinical trial." Cancer Research 82, no. 12_Supplement (2022): CT543. http://dx.doi.org/10.1158/1538-7445.am2022-ct543.

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Abstract Tumor metastasis to the skeleton affects over 70% cancer patients, more than any other site of metastasis Skeletal related events (SREs) included spinal cord compression, fracture, bone radiation or surgery, and tumor-related hypercalcemia are severe complications of bone metastases, which impair patients life quality and require particular treatments The gold standard for the definitive diagnosis is still pathological examination, which needs pre-biopsy imaging review to improve the diagnosis efficacy Classic imaging review method for being CT (Computed Tomography) and 18F-FDG PET/CT

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Li, Yaqi, Chengcheng Li, Peng Cui, et al. "Abstract 4567: Circulating tumor DNA-based molecular residual disease guides treatment in metastatic colorectal cancer patients with no evidence of disease: An open-label, prospective, interventional phase II study." Cancer Research 85, no. 8_Supplement_1 (2025): 4567. https://doi.org/10.1158/1538-7445.am2025-4567.

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Abstract Patients with metastatic colorectal cancer (mCRC) can achieve no evidence of disease (NED) after curative treatment. However, the survival benefit of adjuvant chemotherapy (ACT) for these patients remains uncertain. Circulating tumor DNA (ctDNA)-based molecular residual disease (MRD) detection has shown to help predict recurrence risk in CRC. Recent retrospective studies have indicated that ACT offers no clinical benefit in surgically resected mCRC with negative ctDNA. In this study, we conducted a prospective, interventiaonal clinical trial (NCT05635630) to evaluate the efficacy of c

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Li, Qiao, Dan Lv, Xiaoying Sun, et al. "Abstract PO5-04-01: Inetetamab combined with sirolimus and chemotherapy in HER2 positive metastatic breast cancer patients with abnormal activation of Pi3k/Akt/mTOR pathway after trastuzumab treatment." Cancer Research 84, no. 9_Supplement (2024): PO5–04–01—PO5–04–01. http://dx.doi.org/10.1158/1538-7445.sabcs23-po5-04-01.

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Abstract Objective: To explore the efficacy and safety of Inetetamab Combined with Sirolimus and Chemotherapy in the treatment of human epidermal factor receptor 2 (HER2) positive metastatic breast cancer patients with abnormal activation of Pi3k/Akt/mTOR (PAM) pathway after Trastuzumab treatment. Methods: This prospective multicenter clinical study enrolled HER2 positive metastatic breast cancer patients at the National Cancer Center in China from July 2021 to September 2022 with PAM pathway mutation confirmed by histology or peripheral blood genetic testing. The inclusion criteria included:

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Zhou, W., M. He, R. Zhao, C. Dong, and Z. Gu. "AB1331-HPR ACTIVE DISEASE ACTIVITY IN ANKYLOSIS SPONDYLITIS: WORSE OUTCOMES AND POORER HR-QOL." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1954.2–1954. http://dx.doi.org/10.1136/annrheumdis-2020-eular.6288.

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Background:Ankylosing spondylitis (AS) is a chronic inflammatory disease that mainly affects the sacroiliac joints and the spine, resulting in decline in quality of life[1,2]. Poor QoL is significantly related to high disease activity[3]. However, there is no systematic report on which prognosis indicators are affected by disease activity in AS patients.Objectives:This study aimed to evaluate the patient-reported outcome measures and health-related quality of life (HR-QoL) in AS patients defined on the basis of the Bath Spondylitis Ankylosing Disease Activity Index (BASDAI).Methods:204 AS pati

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Pham, Thanh Binh, Thuy Van Nguyen, Thi Hong Cam Hoang, et al. "Synthesis and deposition of Silver nanostructures on the silica microsphere by laser-assisted photochemical method for SERS applications." Photonics Letters of Poland 12, no. 4 (2020): 97. http://dx.doi.org/10.4302/plp.v12i4.1049.

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The homogeneous distribution of nano-metallic structures on the surface-enhanced Raman (SERS) substrates plays an important factor for high-sensitive Raman scattering measurement. In this paper, we present a low-cost laser-assisted photochemical method for making a SERS probe based on silver nanostructures, which are one-timely synthesized nano-silver structures, homogeneously deposited on silica microsphere surfaces. Achieved SERS-activity substrates with a homogeneous distribution of Ag-nanostructures are verified by a mapping technique on the surface of Ag-coated microsphere for the detecti

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Perez-Sancristobal, I., L. León, M. P. Álvarez Hernandez, et al. "AB1171 PERSISTENT POST-DISCHARGE SYMPTOMS AFTER COVID-19 IN RHEUMATIC AND MUSCULOSKELETAL DISEASES." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1701.1–1701. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4699.

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BackgroundThe COVID-19 pandemic continues worldwide and has had a strong impact on public health. As the pandemic evolves, efforts have been intensified to identify persistent symptoms associated with the infection once resolved have intensified.ObjectivesWe aimed to describe persistent symptoms and sequelae in patients with rheumatic and musculoskeletal diseases (RMD) after admission due to Covid-19. We also compared the role of autoimmune rheumatic diseases (ARD) with that of non–autoimmune rheumatic and musculoskeletal diseases (NARD) in persistent symptoms and sequelae.MethodsWe performed

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Siddiqui, Abdur-Rahman, Jeanne N'Diaye, Kristin Martin, et al. "Monitoring Surface-Enhanced Infrared Absorption Spectroscopy on a Graphitic Electrode for in-Situ Surface-Sensitive Electrochemistry: Designing Electrode Interfaces for Carbon Capture." ECS Meeting Abstracts MA2024-02, no. 60 (2024): 4069. https://doi.org/10.1149/ma2024-02604069mtgabs.

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Combining spectroscopy with electrochemistry enables the monitoring of changes in bonding, molecular orientation, and chemical composition during electrochemical processes at the electrode/electrolyte interface. Surface-enhanced infrared absorption spectroscopy (ATR-SEIRAS) allows a direct in situ monitoring of electrochemical processes occurring at the electrode interface due plasmonic enhancement by surface plasmon polaritons (SPP).1 Electrochemical ATR-SEIRAS has been used extensively for investigating electrocatalysis2,3, characterizing adsorbed species4, and detecting reaction intermediat

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Zhu, Di, Fei Ma, Yiqun Li, et al. "Abstract PS8-01: ZN-1041, a potential best-in-class BBB Penetrable HER2 Inhibitor, has high antitumor activity in patients with Breast Cancer with CNS Metastases." Clinical Cancer Research 31, no. 12_Supplement (2025): PS8–01—PS8–01. https://doi.org/10.1158/1557-3265.sabcs24-ps8-01.

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Abstract Background: An estimated 50% of patients with HER2-positive metastatic breast cancer will develop brain metastases (BCBM). BCBM is associated with shortened overall survival and disruption of quality of life, representing an area of investigation for newer and more effective treatments. Previous studies, including Phase 1a and 1b, have demonstrated that ZN-1041, a HER2 TKI designed to penetrate the blood-brain barrier (BBB) with high selectivity and a broad safety margin, exhibits promising antitumor activity both as monotherapy and in combination with trastuzumab and capecitabine. Th

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Yan, Feng, Tao Jiang, Tao Liang, et al. "Abstract 3318: GFH375 (VS-7375): An oral, selective KRAS G12D (ON/OFF) inhibitor with potent anti-tumor efficacy." Cancer Research 84, no. 6_Supplement (2024): 3318. http://dx.doi.org/10.1158/1538-7445.am2024-3318.

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Abstract Background: KRAS is the best-known oncogene but had long been considered ‘undruggable’ until the approval of the first KRAS G12C inhibitor sotorasib in 2021. However, most current clinical-stage KRAS inhibitors target the KRAS G12C mutation. Inhibitors of other KRAS mutants such as KRAS G12D, the most frequent KRAS mutation in human cancer, are needed for patients. We have developed GFH375 (VS-7375), an oral, selective KRAS G12D inhibitor targeting both “ON” (GTP-bound) and “OFF” (GDP-bound) states of KRAS proteins. The in vitro potency, selectivity, and in vivo efficacy of monotherap

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Dumble, Melissa, Ye Edward Tian, Ali Tabatabaei, et al. "Abstract 5719: Identification of EIK1004 (IMP1707), a CNS-penetrant, potent, and selective PARP1 inhibitor poised for testing in patients with HRD mutant tumors." Cancer Research 85, no. 8_Supplement_1 (2025): 5719. https://doi.org/10.1158/1538-7445.am2025-5719.

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Abstract INTRODUCTION: Nonselective poly(ADP-ribose) polymerase (PARP) inhibitors have proven to be effective in patients whose tumors harbor mutations in DNA repair proteins, although their efficacy is hampered by dose reductions and suspensions due to on-target toxicity resulting from PARP2-related hematologic suppression. Currently available PARP inhibitors have limited brain penetrance, limiting their utility for central nervous system (CNS) tumors or brain metastases. PARP1 inhibition alone can result in an antitumor effect similar to pan-PARP inhibition; therefore, development of PARP1-s

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Jiang, Vivian Changying, Lingzhi Li, Alexa Jordan, et al. "Abstract 3955: Targeting transcription elongation via CDK9 in mantle cell lymphoma patients with dual resistance to BTK inhibition and CAR T therapy." Cancer Research 82, no. 12_Supplement (2022): 3955. http://dx.doi.org/10.1158/1538-7445.am2022-3955.

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Abstract Introduction Clinical relapse following CD19 CAR T therapy after failure to BTK inhibitors (BTKi) is a novel and fast growing medical challenge in treating patients with mantle cell lymphoma (MCL). Thus, developing a novel therapy to overcome this BTKi-CAR T dual resistance (Dual-R) is an urgent need. Our unpublished data revealed MYC targets and cyclin-dependent kinase 9 (CDK9) are highly upregulated in the Dual-R compared to BTKi-R samples. CDK9 is a critical component of the positive transcription elongation factor b (P-TEFb) complex. Its inhibition induces acute decline of short-l

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Hsieh, Kang Lin, Tanjida Kabir, Luis Nunez-Rubiano, et al. "Abstract LB067: A confident and operator-independent deep segmentation model to measure residual tumor volume in the follow-up MRIs for glioblastoma." Cancer Research 83, no. 8_Supplement (2023): LB067. http://dx.doi.org/10.1158/1538-7445.am2023-lb067.

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Abstract Introduction: Magnetic resonance imaging (MRI) is the most common tool to examine glioblastoma. Preoperative MRI can be used to initial diagnosis, and surgery planning, while follow-up MRIs can be used to evaluate treatment responses, identify recurrency, and detect side effects. The follow-up MRIs are usually taken after the first-line therapy, such as maximal safe resection. In the past, radiologists manually segment the tumor regions from normal brain tissue on follow-up MRIs, which is time-consuming, error-prone, and challenging. Several deep-learning (DL) models have been develop

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Ghimire, Govinda, Archana Loganathan, Osama Awadallah, and Bilal El-Zahab. "Sulfurized Electrolyte Additives for Stable Lithium Metal Anodes." ECS Meeting Abstracts MA2022-02, no. 3 (2022): 187. http://dx.doi.org/10.1149/ma2022-023187mtgabs.

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Researchers around the world are striving to develop new materials for energy-efficient and high energy density lithium-ion batteries [1]. Lithium metal with a theoretical specific capacity of 3860 mAh/g, low density (0.534 g/cm3), and the lowest potential (−3.040 V vs. standard hydrogen electrode) is consider the ultimate anode material for high specific energy batteries [2]. However, various issues remain to be address that hinder its use in commercial batteries, namely, cycling stability, Coulombic efficiency, and safety aspects associated with dendritic growth [3]. Inactive lithium, also k

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Franklin, Giovanna Formiga, Omar Hassan, El-Mahdi Halim, Pierre-Louis Taberna, Patrice Simon, and Florence Duclairoir. "Electrochemical Development and Characterization By SECM of 2D Carbon-Based Materials Architectured for Energy Storage and Conversion." ECS Meeting Abstracts MA2022-01, no. 12 (2022): 840. http://dx.doi.org/10.1149/ma2022-0112840mtgabs.

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With the fastly-growing social and commercial demands for portable electronic devices and the need for developing environmentally friendly high-power energy sources, new non-critical, non-toxic materials are currently being widely studied [1]. Electrochemical Double Layer Capacitors, also termed as supercapacitors, store energy electrostatically by charge separation at the high-surface-area porous carbon / electrolyte interface, by charging the electrochemical double layer [2]. Carbon-based materials are the most widely used electrode materials for EDLCs because of their desirable physical-che

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Pirrone, Noemi, Sara Garcia Ballesteros, Simelys Hernandez, and Federico Bella. "Electrochemical Ammonia Production from Wastewater in a Flow Cell Reactor." ECS Meeting Abstracts MA2023-02, no. 47 (2023): 2322. http://dx.doi.org/10.1149/ma2023-02472322mtgabs.

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Although its high carbon footprint, the Haber-Bosh (HB) process mainly dominates the NH3 production market. Indeed, H2 is mainly produced by fossil fuels steam reforming processes and the catalytic reaction between N2 and H2 requires high energy input, being carried out at high temperatures and pressures. Moreover, it should be considered that HB plants are not evenly distributed in the world, thus NH3 and its derivates transportation to the final user is a large portion of the overall environmental impact.1 Moreover, as the population is growing, the NH3 demand is increasing fast to sustain t

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