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Journal articles on the topic 'Childhood apraxia of speech'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Červenková, Barbora. "Childhood apraxia of speech." Pediatrie pro praxi 25, no. 5 (2024): 304–10. http://dx.doi.org/10.36290/ped.2024.058.

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Iuzzini-Seigel, Jenya, and Elizabeth Murray. "Speech Assessment in Children With Childhood Apraxia of Speech." Perspectives of the ASHA Special Interest Groups 2, no. 2 (2017): 47–60. http://dx.doi.org/10.1044/persp2.sig2.47.

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This article uses the International Classification of Functioning (ICF) framework to outline the assessment needs of children with apraxia of speech. Specifically, the level of breakdown for children with apraxia of speech—that of motor planning and programming at the level of body functions—is delineated using operationally defined criteria for greater diagnostic transparency.

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3

Toğram, Bülent. "How Do Families of Children with Down Syndrome Perceive Speech Intelligibility in Turkey?" BioMed Research International 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/707134.

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Childhood verbal apraxia has not been identified or treated sufficiently in children with Down syndrome but recent research has documented that symptoms of childhood verbal apraxia can be found in children with Down syndrome. But, it is not routinely diagnosed in this population. There is neither an assessment tool in Turkish nor any research on childhood verbal apraxia although there is a demand not only for children with Down syndrome but also for normally developing children. The study examined if it was possible to determine oral-motor difficulties and childhood verbal apraxia features in

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4

Wattanawongsawang, Worawan. "Speech Therapy for Childhood Apraxia of Speech." Ramathibodi Medical Journal 42, no. 1 (2019): 55–64. http://dx.doi.org/10.33165/rmj.2019.42.1.113728.

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Childhood apraxia of speech is a neurological speech sound disorder in which the child has inadequate the precision and consistency of movements underlying speech production in the absence of neuromuscular deficits. Children with apraxia of speech require intensive and specialized training in order to enable them to communicate effectively. The principles of the speech therapy program include stimulating speaking and communicating in daily life as well as practicing to speak clearly. The purpose of this article is to discuss the principles of speech therapy based on motor learning, speech stim

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5

Westby, Carol. "Diagnosing Childhood Apraxia of Speech." Word of Mouth 27, no. 1 (2015): 4–8. http://dx.doi.org/10.1177/1048395015598331a.

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6

Hall, Nancy E. "Fluency in Childhood Apraxia of Speech." Perspectives on Fluency and Fluency Disorders 17, no. 2 (2007): 9–14. http://dx.doi.org/10.1044/ffd17.2.9.

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7

Nakamura-Palacios, Ester Miyuki, Aldren Thomazini Falçoni Júnior, Gabriela Lolli Tanese, Ana Carla Estellita Vogeley, and Aravind Kumar Namasivayam. "Enhancing Speech Rehabilitation in a Young Adult with Trisomy 21: Integrating Transcranial Direct Current Stimulation (tDCS) with Rapid Syllable Transition Training for Apraxia of Speech." Brain Sciences 14, no. 1 (2024): 58. http://dx.doi.org/10.3390/brainsci14010058.

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Apraxia of speech is a persistent speech motor disorder that affects speech intelligibility. Studies on speech motor disorders with transcranial Direct Current Stimulation (tDCS) have been mostly directed toward examining post-stroke aphasia. Only a few tDCS studies have focused on apraxia of speech or childhood apraxia of speech (CAS), and no study has investigated individuals with CAS and Trisomy 21 (T21, Down syndrome). This N-of-1 randomized trial examined the effects of tDCS combined with a motor learning task in developmental apraxia of speech co-existing with T21 (ReBEC RBR-5435x9). The

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8

Chenausky, Karen, Amanda Brignell, Angela Morgan, and Helen Tager-Flusberg. "Motor speech impairment predicts expressive language in minimally verbal, but not low verbal, individuals with autism spectrum disorder." Autism & Developmental Language Impairments 4 (January 2019): 239694151985633. http://dx.doi.org/10.1177/2396941519856333.

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Background and aims Developmental motor speech impairment has been suspected, but rarely systematically examined, in low- and minimally verbal individuals with autism spectrum disorder. We aimed to investigate the extent of motor speech impairment in this population and its relation to number of different words produced during a semi-structured language sample. Methods Videos of 54 low-verbal and minimally verbal individuals (ages 4;4–18;10) performing portions of a speech praxis test were coded for signs of motor speech impairment (e.g., childhood apraxia of speech). Age, autism spectrum diso

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9

Nijland, Lian, Hayo Terband, and Ben Maassen. "Cognitive Functions in Childhood Apraxia of Speech." Journal of Speech, Language, and Hearing Research 58, no. 3 (2015): 550–65. http://dx.doi.org/10.1044/2015_jslhr-s-14-0084.

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Purpose Childhood apraxia of speech (CAS) is diagnosed on the basis of specific speech characteristics, in the absence of problems in hearing, intelligence, and language comprehension. This does not preclude the possibility that children with this speech disorder might demonstrate additional problems. Method Cognitive functions were investigated in 3 domains: complex sensorimotor and sequential memory functions, simple sensorimotor functions, and nonrelated control functions. Seventeen children with CAS were compared with 17 children with normal speech development at 2 occasions within 15 mont

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10

Preston, Jonathan L., Peter J. Molfese, Nina Gumkowski, et al. "Neurophysiology of Speech Differences in Childhood Apraxia of Speech." Developmental Neuropsychology 39, no. 5 (2014): 385–403. http://dx.doi.org/10.1080/87565641.2014.939181.

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11

Macrae, Toby, Kaitlin Lansford, and Emily Berteau. "Speech variability and prosody in childhood apraxia of speech." Journal of the Acoustical Society of America 138, no. 3 (2015): 1944. http://dx.doi.org/10.1121/1.4934145.

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12

Baylis, Adriane L., and Lawrence D. Shriberg. "Estimates of the Prevalence of Speech and Motor Speech Disorders in Youth With 22q11.2 Deletion Syndrome." American Journal of Speech-Language Pathology 28, no. 1 (2019): 53–82. http://dx.doi.org/10.1044/2018_ajslp-18-0037.

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Purpose Speech sound disorders and velopharyngeal dysfunction are frequent features of 22q11.2 deletion syndrome (22q). We report the first estimate of the prevalence of motor speech disorders (MSDs) in youth with 22q. Method Seventeen children and adolescents with 22q completed an assessment protocol that included a conversational speech sample. Data reduction included phonetic transcription, perceptual speech ratings, prosody-voice coding, and acoustic analyses. Data analyses included 3 motor speech measures and a cross-classification analytic. Prevalence estimates of speech and MSDs in yout

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13

Namasivayam, Aravind K., Margit Pukonen, Debra Goshulak, et al. "Treatment intensity and childhood apraxia of speech." International Journal of Language & Communication Disorders 50, no. 4 (2015): 529–46. http://dx.doi.org/10.1111/1460-6984.12154.

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Velleman, Shelley L., and Carolyn B. Mervis. "Children With 7q11.23 Duplication Syndrome: Speech, Language, Cognitive, and Behavioral Characteristics and Their Implications for Intervention." Perspectives on Language Learning and Education 18, no. 3 (2011): 108–16. http://dx.doi.org/10.1044/lle18.3.108.

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7q11.23 duplication syndrome is a recently documented genetic disorder associated with severe speech delay, language delay, a characteristic facies, hypotonia, developmental delay, and social anxiety. Children with this syndrome demonstrate developmentally appropriate nonverbal pragmatic abilities in socially comfortable situations. Motor speech disorder (childhood apraxia of speech and/or dysarthria), oral apraxia, and/or phonological disorder, or symptoms of these disorders, are common, as are characteristics consistent with expressive language disorder. Intensive speech/language therapy is

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15

Vuolo, Janet, and Lisa Goffman. "Language Skill Mediates the Relationship Between Language Load and Articulatory Variability in Children With Language and Speech Sound Disorders." Journal of Speech, Language, and Hearing Research 61, no. 12 (2018): 3010–22. http://dx.doi.org/10.1044/2018_jslhr-l-18-0055.

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Purpose The aim of the study was to investigate the relationship between language load and articulatory variability in children with language and speech sound disorders, including childhood apraxia of speech. Method Forty-six children, ages 48–92 months, participated in the current study, including children with speech sound disorder, developmental language disorder (aka specific language impairment), childhood apraxia of speech, and typical development. Children imitated (low language load task) then retrieved (high language load task) agent + action phrases. Articulatory variability was quan

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Shakibayi, Mersede Imani, Talieh Zarifian, and Nasibeh Zanjari. "Speech characteristics of childhood apraxia of speech: A survey research." International Journal of Pediatric Otorhinolaryngology 126 (November 2019): 109609. http://dx.doi.org/10.1016/j.ijporl.2019.109609.

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17

Tarshis, Nancy, Michelle Garcia Winner, and Pamela Crooke. "What Does It Mean to Be Social? Defining the Social Landscape for Children With Childhood Apraxia of Speech." Perspectives of the ASHA Special Interest Groups 5, no. 4 (2020): 843–52. http://dx.doi.org/10.1044/2020_persp-19-00116.

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Purpose What does it mean to be social? In addition, how is that different from behaving socially appropriately? The purpose of this clinical focus article is to tackle these two questions along with taking a deeper look into how communication challenges in childhood apraxia of speech impact social competencies for young children. Through the lens of early social development and social competency, this clinical focus article will explore how speech motor challenges can impact social development and what happens when young learners miss early opportunities to grow socially. While not the primar

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18

Grigos, Maria I., Aviva Moss, and Ying Lu. "Oral Articulatory Control in Childhood Apraxia of Speech." Journal of Speech, Language, and Hearing Research 58, no. 4 (2015): 1103–18. http://dx.doi.org/10.1044/2015_jslhr-s-13-0221.

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Purpose The purpose of this research was to examine spatial and temporal aspects of articulatory control in children with childhood apraxia of speech (CAS), children with speech delay characterized by an articulation/phonological impairment (SD), and controls with typical development (TD) during speech tasks that increased in word length. Method The participants included 33 children (11 CAS, 11 SD, and 11 TD) between 3 and 7 years of age. A motion capture system was used to track jaw, lower lip, and upper lip movement during a naming task. Movement duration, velocity, displacement, and variabi

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19

Cecilia dos Santos Marques, Maria, Silvana Griz, Kelly Cristina Lira de Andrade, Pedro de Lemos Menezes, and Denise Costa Menezes. "Frequency Following Responses in childhood apraxia of speech." International Journal of Pediatric Otorhinolaryngology 145 (June 2021): 110742. http://dx.doi.org/10.1016/j.ijporl.2021.110742.

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20

Tubul-Lavy, Gila. "Imitation and Naming in Childhood Apraxia of Speech." International Journal of Speech & Language Pathology and Audiology 3, no. 1 (2015): 32–39. http://dx.doi.org/10.12970/2311-1917.2015.03.01.5.

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21

Gretz, Sharon, and Kathy Bauer. "Michigan Insurer Rules on Childhood Apraxia of Speech." ASHA Leader 9, no. 10 (2004): 1–28. http://dx.doi.org/10.1044/leader.pa.09102004.1.

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22

Lewis, Barbara A., and Barbara L. Ekelman. "Literacy Problems Associated With Childhood Apraxia of Speech." Perspectives on Language Learning and Education 14, no. 3 (2007): 10–17. http://dx.doi.org/10.1044/lle14.3.10.

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23

VASHDI, Elad, Amit AVRAMOV, Špela FALATOV, Huang YI-CHEN, Jiang PEI-RU, and Paula Teodora MAMINA-CHIRIAC. "Childhood Apraxia of Speech. Developmental Speech Patterns. A Wide Retrospective Study." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 11, no. 3 Sup.1 (2020): 54–68. https://doi.org/10.18662/brain/11.3Sup1/122.

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Patterns of a phenomenon define the entity. If oneunderstands the patterns of the maze, he can find his way there. Patternsof colors on a dress will hold its characters and soul. Understanding theexpressive patterns of a developmental syndrome enables treating it withsuccess. It is true for treating Childhood Apraxia of speech (CAS) aswell. CAS as motor-speech disorder involves difficulties in soundsproduction for speech purposes. The difficulties can be demonstrated inpatterns that would be specific to CAS. These patterns can distinguishone phenomenon from another.A retrospective research was

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Cabral, C., and F. Fernandes. "Correlations between autism spectrum disorders and childhood apraxia of speech." European Psychiatry 64, S1 (2021): S209. http://dx.doi.org/10.1192/j.eurpsy.2021.557.

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IntroductionAutism Spectrum Disorder (ASD), is a neurodevelopmental disorder, characterized by inabilities in communication and social interaction. ¹ Childhood Apraxia of Speech (CAS) is a neurological disorder in which the consistency and precision of speech movements are impaired, in the absence of neuromuscular deficits.2 Research indicates that children with ASD do not have a higher prevalence of CAS.3 It is suggested that comorbid ASD and CAS would be expected to be extremely rare.ObjectivesVerify the occurrence of CAS in children with ASD.Methods The study included 22 children diagnosed

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Vashdi, Elad, Amit Avramov, Špela Falatov, Huang Yi-Chen, Jiang Pei-Ru, and Paula Teodora Mamina-Chiriac. "Childhood Apraxia of Speech. Developmental Speech Patterns. A Wide Retrospective Study." BRAIN. Broad Research in Artificial Intelligence and Neuroscience 11, no. 3sup1 (2020): 54–68. http://dx.doi.org/10.18662/brain/11.3sup1/122.

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Patterns of a phenomenon define the entity. If one understands the patterns of the maze, he can find his way there. Patterns of colors on a dress will hold its characters and soul. Understanding the expressive patterns of a developmental syndrome enables treating it with success. It is true for treating Childhood Apraxia of speech (CAS) as well. CAS as motor-speech disorder involves difficulties in sounds production for speech purposes. The difficulties can be demonstrated in patterns that would be specific to CAS. These patterns can distinguish one phenomenon from another. A retrospective res

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Tychyna, Kateryna, Natalia Babych, Yevheniia Lyndinа, and Olena Revutska. "The impact of Playdough games on the development of oral motor skills in preschool children with childhood apraxia of speech." Scientific Bulletin of Mukachevo State University Series “Pedagogy and Psychology” 10, no. 3 (2024): 51–60. http://dx.doi.org/10.52534/msu-pp3.2024.51.

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The relevant challenges are the use of innovative approaches that conserve both the speech therapist’s and the child’s resources while addressing multiple goals in speech therapy. The authors of this article have adopted such an approach to develop oral motor skills, which are crucial for speech development in preschoolers, particularly those with childhood apraxia of speech. This study aimed to evaluate the effectiveness of an author-developed therapy using Playdough games for preschool children with childhood apraxia of speech. A controlled design with repeated measures was employed. The pri

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Wang, Huili, Shurong Zhang, and Xueyan Li. "Visualizing the Knowledge Domain of Motor Speech Disorders: A Scientific Review (2000-2019)." Chinese Journal of Applied Linguistics 44, no. 4 (2021): 563–88. http://dx.doi.org/10.1515/cjal-2021-0035.

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Abstract This review visualizes the knowledge domain of motor speech disorders (MSDs) in linguistics between 2000 and 2019 by means of scientometric methods. With topic searches, the study collected 869 bibliographic records and 20, 411 references from Web of Science Core Collection (WoSCC) of Thomson Reuter. The clustered and visualized document co-citation network of the MSDs knowledge domain in CiteSpace identifies 15 research foci in different periods, including apraxia of speech, acoustics, children, technology, aphemia, childhood apraxia of speech, primary progressive aphasia, speech mot

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McKechnie, Jacqueline, Mostafa Shahin, Beena Ahmed, Patricia McCabe, Joanne Arciuli, and Kirrie J. Ballard. "An Automated Lexical Stress Classification Tool for Assessing Dysprosody in Childhood Apraxia of Speech." Brain Sciences 11, no. 11 (2021): 1408. http://dx.doi.org/10.3390/brainsci11111408.

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Childhood apraxia of speech (CAS) commonly affects the production of lexical stress contrast in polysyllabic words. Automated classification tools have the potential to increase reliability and efficiency in measuring lexical stress. Here, factors affecting the accuracy of a custom-built deep neural network (DNN)-based classification tool are evaluated. Sixteen children with typical development (TD) and 26 with CAS produced 50 polysyllabic words. Words with strong–weak (SW, e.g., dinosaur) or WS (e.g., banana) stress were fed to the classification tool, and the accuracy measured (a) against ex

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Preston, Jonathan L., Nickole Brick, and Nicole Landi. "Ultrasound Biofeedback Treatment for Persisting Childhood Apraxia of Speech." American Journal of Speech-Language Pathology 22, no. 4 (2013): 627–43. http://dx.doi.org/10.1044/1058-0360(2013/12-0139).

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Purpose The purpose of this study was to evaluate the efficacy of a treatment program that includes ultrasound biofeedback for children with persisting speech sound errors associated with childhood apraxia of speech (CAS). Method Six children ages 9–15 years participated in a multiple baseline experiment for 18 treatment sessions during which treatment focused on producing sequences involving lingual sounds. Children were cued to modify their tongue movements using visual feedback from real-time ultrasound images. Probe data were collected before, during, and after treatment to assess word-lev

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Brown, Taylor M., Becky S. Baas, Ruth E. Stoeckel, Lee A. Belf, and Gayla L. Poling. "Assessment of Children With Hearing Loss and Co-Occurring Medical Disorders: Challenging Cases." Perspectives of the ASHA Special Interest Groups 6, no. 2 (2021): 375–83. http://dx.doi.org/10.1044/2021_persp-20-00080.

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Purpose Assessing children with hearing loss and co-occurring medical disorders can be challenging. The purpose of this clinical focus article is to highlight multidisciplinary decision making and evaluation considerations when assessing communication skills of children with hearing loss and co-occurring disorders: velopharyngeal insufficiency, childhood apraxia of speech, and autism spectrum disorder. Method Case examples are described to illustrate multidisciplinary decision-making processes for assessing the communication skills of children with hearing loss who have co-occurring velopharyn

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Sayahi, Fatemeh, and Shohreh Jalaie. "Diagnosis of Childhood Apraxia of Speech: A Systematic Review." Journal of Diagnostics 3, no. 1 (2016): 21–26. http://dx.doi.org/10.18488/journal.98/2016.3.1/98.1.21.26.

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32

Bombonato, Clara, Claudia Casalini, Chiara Pecini, et al. "Implicit learning in children with Childhood Apraxia of Speech." Research in Developmental Disabilities 122 (March 2022): 104170. http://dx.doi.org/10.1016/j.ridd.2021.104170.

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Maas, Edwin, Christine E. Butalla, and Kimberly A. Farinella. "Feedback Frequency in Treatment for Childhood Apraxia of Speech." American Journal of Speech-Language Pathology 21, no. 3 (2012): 239–57. http://dx.doi.org/10.1044/1058-0360(2012/11-0119).

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Westby, Carol. "Literacy Skills of Children With Childhood Apraxia of Speech." Word of Mouth 36, no. 2 (2024): 8–12. http://dx.doi.org/10.1177/10483950241282889b.

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35

Caspari, Susan S., Edythe A. Strand, Suresh Kotagal, and Christina Bergqvist. "Obstructive Sleep Apnea, Seizures, and Childhood Apraxia of Speech." Pediatric Neurology 38, no. 6 (2008): 422–25. http://dx.doi.org/10.1016/j.pediatrneurol.2008.03.002.

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36

Chenausky, Karen V., Amanda Brignell, Angela Morgan, et al. "Factor analysis of signs of childhood apraxia of speech." Journal of Communication Disorders 87 (September 2020): 106033. http://dx.doi.org/10.1016/j.jcomdis.2020.106033.

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37

Ballard, Kirrie J., Donald A. Robin, Patricia McCabe, and Jeannie McDonald. "A Treatment for Dysprosody in Childhood Apraxia of Speech." Journal of Speech, Language, and Hearing Research 53, no. 5 (2010): 1227–45. http://dx.doi.org/10.1044/1092-4388(2010/09-0130).

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38

Knežević, Dora. "Motor abilities of children with childhood apraxia of speech." Hrvatska revija za rehabilitacijska istraživanja 58, no. 2 (2022): 81–91. http://dx.doi.org/10.31299/hrri.58.2.5.

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Previous studies on fine and gross motor skills of children with childhood apraxia of speech (CAS) have reported inconclusive results. In this study, we investigate the motor abilities of children with CAS by focusing on three distinct motor factors: control during movement, fine motor skills/handwriting, and general coordination. Participants included 25 children with CAS and 20 age-matched typically developing (TD) children between the ages of 5 and 7 years. Motor abilities were evaluated using a parent questionnaire - the Croatian version of The Developmental Coordination Disorder Questionn

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Malmenholt, Ann, Anette Lohmander, and Anita McAllister. "Childhood apraxia of speech: A survey of praxis and typical speech characteristics." Logopedics Phoniatrics Vocology 42, no. 2 (2016): 84–92. http://dx.doi.org/10.1080/14015439.2016.1185147.

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40

Beiting, Molly, and Edwin Maas. "Autism-Centered Therapy for Childhood Apraxia of Speech (ACT4CAS): A Single-Case Experimental Design Study." American Journal of Speech-Language Pathology 30, no. 3S (2021): 1525–41. http://dx.doi.org/10.1044/2020_ajslp-20-00131.

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Purpose A subset of children with autism spectrum disorder (ASD) has speech sound disorders, including childhood apraxia of speech (CAS). To date, virtually all speech treatment studies consider ASD an exclusionary criterion, resulting in little scientific evidence for treatment of CAS for children who also have ASD. This study proposes and tests a novel approach, Autism-Centered Therapy for Childhood Apraxia of Speech (ACT4CAS), as a theoretically and clinically informed speech treatment option for this population. Method Using a multiple-baseline design within and across participants, three

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Murray, Elizabeth, Patricia McCabe, Robert Heard, and Kirrie J. Ballard. "Differential Diagnosis of Children with Suspected Childhood Apraxia of Speech." Journal of Speech, Language, and Hearing Research 58, no. 1 (2015): 43–60. http://dx.doi.org/10.1044/2014_jslhr-s-12-0358.

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Purpose The gold standard for diagnosing childhood apraxia of speech (CAS) is expert judgment of perceptual features. The aim of this study was to identify a set of objective measures that differentiate CAS from other speech disorders. Method Seventy-two children (4–12 years of age) diagnosed with suspected CAS by community speech-language pathologists were screened. Forty-seven participants underwent diagnostic assessment including presence or absence of perceptual CAS features. Twenty-eight children met two sets of diagnostic criteria for CAS (American Speech-Language-Hearing Association, 20

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Vuolo, Janet, and Alan Wisler. "Acoustic analysis of spatiotemporal variability in children with childhood apraxia of speech." Journal of the Acoustical Society of America 152, no. 4 (2022): A139. http://dx.doi.org/10.1121/10.0015814.

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Childhood apraxia of speech (CAS) is a pediatric neurological motor speech disorder characterized by impaired speech execution in the absence of neuromuscular deficits. Children with CAS show distinct speech features, including sequencing, coarticulation, and prosodic deficits, compared to children with other speech disorders. The core deficit in CAS is at the level of planning and programming the precise spatiotemporal parameters of movement sequences necessary to produce natural-sounding speech. This study will investigate spatiotemporal variability in children with CAS compared to children

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Swartz, Michelle T., Laura Koenig, and Elaine R. Hitchcock. "Acoustic analysis of voicing errors in children with childhood apraxia of speech." Journal of the Acoustical Society of America 153, no. 3_supplement (2023): A291. http://dx.doi.org/10.1121/10.0018890.

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Childhood apraxia of speech (CAS) is a complex neurological speech sound disorder (SSD) that involves impaired speech motor planning and programming. Speech characteristics of CAS include difficulty sequencing speech movements in the absence of muscle weakness resulting in segmental and suprasegmental speech deficits. Past work indicates that children with CAS are delayed in acquisition of voicing contrasts, and are often perceived to produce errors or distortions of voicing. However, not all past studies employed acoustic analyses to assess voicing characteristics in CAS. This study will use

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Stoeckel, Ruth, and Susan Caspari. "Childhood Apraxia of Speech: Clinical Decision Making From a Motor-Based Perspective." Perspectives of the ASHA Special Interest Groups 5, no. 4 (2020): 831–42. http://dx.doi.org/10.1044/2020_persp-19-00090.

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Purpose This article uses two case studies to illustrate clinical decision making using the best available evidence to approach the assessment and intervention for children with childhood apraxia of speech. The cases represent children seen in the authors' clinical practice, with personal information altered or omitted to protect the identity of the individuals. The case discussions exemplify choices that may be made for children of different ages, highlighting common elements across ages, as well as treatment aspects that may differ by age. Conclusions While research regarding best practice f

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Hildebrand, Michael S., Victoria E. Jackson, Thomas S. Scerri, et al. "Severe childhood speech disorder." Neurology 94, no. 20 (2020): e2148-e2167. http://dx.doi.org/10.1212/wnl.0000000000009441.

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ObjectiveDetermining the genetic basis of speech disorders provides insight into the neurobiology of human communication. Despite intensive investigation over the past 2 decades, the etiology of most speech disorders in children remains unexplained. To test the hypothesis that speech disorders have a genetic etiology, we performed genetic analysis of children with severe speech disorder, specifically childhood apraxia of speech (CAS).MethodsPrecise phenotyping together with research genome or exome analysis were performed on children referred with a primary diagnosis of CAS. Gene coexpression

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Swartz, Michelle T., Laura Koenig, and Elaine R. Hitchcock. "Acoustic analysis of vowel production in children with childhood apraxia of speech." Journal of the Acoustical Society of America 151, no. 4 (2022): A44—A45. http://dx.doi.org/10.1121/10.0010606.

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Childhood apraxia of speech (CAS) is a complex neurological subtype of speech sound disorder (SSD), involving impaired speech motor planning and programming. Speech characteristics of CAS include difficulty in sequencing speech movements in the absence of muscle weakness resulting in segmental (e.g., vowel/consonant distortions) and suprasegmental (e.g., inappropriate lexical stress) speech deficits. Acoustic analysis offers a robust objective diagnostic measurement of CAS for lexical stress and consonant accuracy/consistency. However, other reported CAS features, such as vowel errors and dist

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Kyra Skoog and Edwin Maas. "Predicting Intelligibility: An Investigation of Speech Sound Accuracy in Childhood Apraxia of Speech." CommonHealth 1, no. 2 (2020): 44–56. http://dx.doi.org/10.15367/ch.v1i2.397.

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Background: Childhood apraxia of speech (CAS) is a pediatric speech disorder that significantly affects communication and life participation. Most CAS treatment research uses speech accuracy as primary outcome measure, on the assumption that accuracy predicts communicative success. However, this relationship has not yet been examined in this population, limiting our understanding of the impact of available treatments. Purpose: The purpose of this study is to explore the relationship between speech accuracy and intelligibility in children with CAS. Intelligibility is defined here as the p

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Springle, Alisha P., Amber Breeden, and Anastasia M. Raymer. "Speech Intervention Effects for Childhood Apraxia of Speech: Quality Appraisal of Systematic Reviews." Perspectives of the ASHA Special Interest Groups 5, no. 3 (2020): 646–53. http://dx.doi.org/10.1044/2020_persp-19-00019.

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Purpose A number of justification have examined the effects of speech interventions on outcomes in childhood apraxia of speech (CAS). The findings have been summarized in the form of systematic reviews (SRs) and meta-analyses, which are used to support evidence-based clinical practice decisions. Yet without acceptable rigor, SRs/meta-analyses may be biased in their recommendations. We appraised the quality of existing SRs for CAS treatment using a tool developed within epidemiology, the AMSTAR-2 (A MeaSurement Tool to Assess Systematic Reviews). Method A search of five databases to identify pu

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Iuzzini-Seigel, Jenya. "Motor Performance in Children With Childhood Apraxia of Speech and Speech Sound Disorders." Journal of Speech, Language, and Hearing Research 62, no. 9 (2019): 3220–33. http://dx.doi.org/10.1044/2019_jslhr-s-18-0380.

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Terband, Hayo, Ben Maassen, Frank H. Guenther, and Jonathan Brumberg. "Computational Neural Modeling of Speech Motor Control in Childhood Apraxia of Speech (CAS)." Journal of Speech, Language, and Hearing Research 52, no. 6 (2009): 1595–609. http://dx.doi.org/10.1044/1092-4388(2009/07-0283).

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